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210. Free-Radical Yields in Proton Irradiation of Oriented DNA: Relationship to Energy Transfer Along DNA Chains

Author

ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD, Miller, J. H., Frasco, D. L., Ye, M., Swenberg, C. E., Myers, L. S., Jr, ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD, Miller, J. H., Frasco, D. L., Ye, M., Swenberg, C. E., and Myers, L. S., Jr

Abstract

Spatial patterns of energy deposition on the nanometer scale are currently believed to be a major factor in determining the biological effectiveness of ionizing radiation. If the most common precursors of biologically significant lesions are clusters of ionization in or near DNA, then intramolecular energy and charge transfer along DNA chains could be very important in lesion development. This paper describes investigations of these phenomena through model calculations and measurements of radical yields in oriented DNA exposed to proton irradiation.

Published
1993

212. AFRRI Reports Second Quarter, April-June 1991

Author

ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD, Brook, Itzhak, Chock, Stephen P., Cockerham, L. G., Dubois, Andre, Elliott, T. E., Liu, Y. X., Madonna, Gary S., Miller, J. H., Miller, John H., ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD, Brook, Itzhak, Chock, Stephen P., Cockerham, L. G., Dubois, Andre, Elliott, T. E., Liu, Y. X., Madonna, Gary S., Miller, J. H., and Miller, John H.

Abstract

Partial Contents: Oral ofloxacin therapy of Pseudomonas aeruginosa sepsis in mice after irradiation; Linking phospholipase A2 to phospholipid turnover and prostaglandin synthesis in mast cell granules; Effects of aminoguanidine on pre- and post-irradiation regional cerebral blood flow, systemic blood pressure and plasma histamine levels in the primate; Gastric injury and invasion of parietal cells by spiral bacteria in rhesus monkeys: Are gastritis and hyperchlorhydria infectious diseases? Quantitative study of wound infection in irradiated mice; Interaction of leukotriene C4 and Chinese hamster lung fibroblasts (V79A03 cells). 2. Subcellular distribution of binding and unlikely role of glutathione-S-transferase; Treatment of mice with sepsis following irradiation and trauma with antibiotics and synthetic trehalose dicorynomycolate (S-TDCM); Negative supercoiling increases the sensitivity of plasmid DNA to single-strand break induction by x-rays; Radical yields in DNA exposed to ionizing radiation: Role of energy and charge transfer; Characterization of human phagocytic cell receptors for C5A and platelet activating factor expressed in Xenopus oocytes; Role of cytokines (interleukin 1, tumor necrosis factor, and transforming growth factor Beta in natural and lipopolysaccharide-enhanced radioresistance; Administration of interleukin-6 stimulates multilineage hematopoiesis and accelerates recovery from radiation-induced hematopoeitic depression., Supplementary Note: Includes Rept. Nos. AFRRI-SR91-22 thru AFRRI-SR91-35 and AFRRI-TR-91-1. Antimicrobial Agents and Chemotherapy, Jul 1990, pp. 1387-1389.

Published
1991

215. Application of Multi-Frequency Modulation (MFM) for high-speed data communications to a voice frequency channel

Author

Moose, P.H., Miller, J. H., Naval Postgraduate School (U.S.), Department of Electrical and Computer Engineering, Salsman, Charles P., Moose, P.H., Miller, J. H., Naval Postgraduate School (U.S.), Department of Electrical and Computer Engineering, and Salsman, Charles P.

Abstract

Multi-Frequency Modulation (MFM) has been developed at NPS using both differential quadrature-phase-shift-keying (DQPSK) and differential-quadrature- amplitude-modulation (DQAM) encoding formats. Previous applications of these encoding formats were on industry standard computers (PC) over a 16-20 kHz channel. This report discusses the implementation of MFM to a voice frequency channel of 200-3400 Hz, for possible future use with high-speed modems over switched telephone networks. Research and testing for this report included the DQPSK and differential 16-quadrature-amplitude-modulation (D16-QAM) encoding formats implemented on PCs. Experimental results of the implemented MFM signal were comparable to theory with acceptable bit error rates for input signal-to-noise ratios (SNR) of 15 dB and higher.

Published
1990

218. Interlaboratory Study of the Analysis of Amoxicillin by Liquid Chromatography

Author

Yongxin, Zhu, primary, Roets, E., additional, Bruzzi, A., additional, Smelt, A. J. W., additional, Van der Vlies, C., additional, Betto, P., additional, Moreno, M. L., additional, Porqueras, E., additional, Wendebourg, H. H., additional, Sinivuo, K., additional, De Kaste, D., additional, Mayrhofer, A., additional, Graby, N., additional, Kister, G., additional, McB Miller, J. H., additional, Nap, C. J., additional, Spieser, J. M., additional, and Hoogmartens, J., additional

Published
1996
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220. lacrepressor: structure and genetics

Author

Lewis, M., primary, Kercher, M. A., additional, Chang, G., additional, Horton, N. C., additional, Miller, J. H., additional, Pace, H. C., additional, and Lu, P., additional

Published
1996
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240. Sb/GaSb heterostructures and multilayers

Author

Golding, T. D., primary, Dura, J. A., additional, Wang, W. C., additional, Vigliante, A., additional, Moss, S. C., additional, Chen, H. C., additional, Miller, J. H., additional, Hoffman, C. A., additional, and Meyer, J. R., additional

Published
1993
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