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204. Morbus Addison als seltene Ursache für chronisch erhöhte Transaminasen

Author

V Stepan, M. Trauner, Vanessa Stadlbauer, H Warnkross, and G. C. Gurakuqi

Subjects
medicine.medical_specialty, medicine.diagnostic_test, Hyperkalemia, business.industry, Fatty liver, Gastroenterology, Autoimmune hepatitis, medicine.disease, Endocrinology, Addison's disease, Internal medicine, medicine, medicine.symptom, Viral hepatitis, business, Liver function tests, Hyponatremia, Adrenocortical Insufficiency
Abstract

Common causes of chronically elevated serum liver enzymes include fatty liver disease, chronic viral hepatitis, autoimmune hepatitis, or hereditary metabolic disorders. Adrenocortical insufficiency can also cause elevated liver enzymes. Since 1990 only 11 cases have been reported. We here report a 52-year-old man with elevated liver enzymes (1.5 x upper limit of normal) over the past 10 years. Furthermore, hyponatremia and hyperkalemia were noted. He complained of fatigue and low blood pressure over the past few years. At physical examination a dark complexion was noted. After ruling out chronic viral hepatitis, autoimmune disease, metabolic or hereditary disorders, rare causes of elevated liver enzymes were considered. The endocrinological work-up revealed Addison's disease as cause of serum electrolyte disturbance and elevated liver enzymes. The patient was successfully treated with hydrocortisol and fludrocortisol. After one week, liver enzymes, serum electrolytes and arterial blood pressure had normalized. In conclusion, for patients with constantly elevated liver enzymes also rare, extrahepatic diseases have to be considered. Addison's disease is a rare but fully reversible cause for elevated liver enzymes.

Published
2006

205. 1053 Bloom of Fecal Megamonas After a 4 Week High Oral Fructose Challenge Disturbs Energy and Lipid Metabolism: Linking Diet to Microbiota, Bile Acid and Host Metabolism Alterations

Author

Femke-Anouska Heinsen, Claudia D. Fuchs, Andre Franke, Werner Dolak, Michael Forster, Stefan Traussnigg, P Munda, Tatjana Stojakovic, Günter Fauler, Emina Halilbasic, Christian Kienbacher, M. Trauner, and Malte C. Rühlemann

Subjects
Hepatology, Bile acid, biology, medicine.drug_class, Host (biology), Gastroenterology, Lipid metabolism, Metabolism, biology.organism_classification, Biochemistry, medicine, Fructose challenge, Bloom, Feces, Megamonas
Published
2016

207. Sa1579 Durable Response in the Markers of Cholestasis through 18 Months of Open-Label Long Term Safety Extension Study of Obeticholic Acid in Primary Biliary Cirrhosis

Author

Giuseppe Mazzella, Jaroslaw Regula, Bettina E. Hansen, Paul J. Pockros, M. Trauner, Simone I. Strasser, David Shapiro, Pietro Invernizzi, Annarosa Floreani, Mitchell L. Shiffman, Simon Hohenester, Joost P.H. Drenth, Christopher L. Bowlus, Catherine Vincent, T. Marmon, Leigh MacConell, Frederik Nevens, Victor Vargas, Pietro Andreone, Velimir A. Luketic, and Karel J. van Erpecum

Subjects
medicine.medical_specialty, Hepatology, business.industry, Extension study, Gastroenterology, Obeticholic acid, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Primary biliary cirrhosis, Cholestasis, chemistry, 030220 oncology & carcinogenesis, Internal medicine, medicine, Long term safety, Open label, business, 030217 neurology & neurosurgery
Published
2016

208. The Non-Steroidal Fxr Agonist Gs-9674 Reduces Liver Fibrosis and Ameliorates Portal Hypertension in a Rat Nash Model

Author

M. Trauner, Eva Hambruch, Michael Burnet, Claus Kremoser, Philipp Schwabl, P Supper, Thomas Reiberger, and Markus Peck-Radosavljevic

Subjects
Agonist, Hepatology, medicine.drug_class, business.industry, Liver fibrosis, Pharmacology, medicine.disease, Non steroidal, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Portal hypertension, 030211 gastroenterology & hepatology, Nash model, business
Published
2016

209. High Risk for Hepatocellular Carcinoma in Cirrhotic Patients with SVR following IFN-Free Daa Treatment within 1 Year Follow-Up

Author

K. Kozbial, R. Stern, C. Freissmuth, S. Beinhardt, A.F. Stättermayer, P. Munda, M. Trauner, P. Ferenci, H. Hofer, and Viral Hepatitis

Subjects
0301 basic medicine, medicine.medical_specialty, Hepatology, business.industry, 1 year follow up, medicine.disease, Ifn free, Gastroenterology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Hepatocellular carcinoma, Internal medicine, medicine, 030211 gastroenterology & hepatology, business
Published
2016

210. Norursodeoxycholic Acid Improves Cholestasis in Primary Sclerosing Cholangitis: Results of a Phase II Dose Finding Study

Author

Peter Fickert, Roland Greinwald, M.P. Manns, Christoph Schramm, Roger W. Chapman, Hanns-Ulrich Marschall, Florian P. Reiter, Emina Halilbasic, E. Schrumpf, Annika Bergquist, Gideon M. Hirschfield, Frederik Nevens, Martti Färkkilä, István Altorjay, M. Trauner, Pröls Markus, and Ulrich Spengler

Subjects
medicine.medical_specialty, Hepatology, business.industry, medicine.disease, Gastroenterology, Primary sclerosing cholangitis, 03 medical and health sciences, Dose finding, 0302 clinical medicine, Cholestasis, 030220 oncology & carcinogenesis, Phase (matter), Internal medicine, Medicine, 030211 gastroenterology & hepatology, business
Published
2016

213. Gut-Liver Axis in Cystic Fibrosis: Lack of Association between Intestinal Inflammation and Liver Disease in Adult Cystic Fibrosis Patients after Lung Transplantation

Author

W. Klepetko, Katharina Staufer, P. Jaksch, M. Trauner, D. Schmidt, S. Schick, H. Vogelsang, Emina Halilbasic, A. Brichta, and Lili Kazemi-Shirazi

Subjects
Liver disease, medicine.medical_specialty, Hepatology, business.industry, Intestinal inflammation, Internal medicine, medicine.medical_treatment, medicine, Lung transplantation, medicine.disease, business, Cystic fibrosis, Gastroenterology
Published
2016

214. Effect of Fibrate-Add-On Treatment in Primary Biliary Cholangitis Patients with an Insufficient Response to Ursodeoxycholic Acid

Author

Emina Halilbasic, AF Stättermayer, R Stern, Harald Hofer, Peter Ferenci, Karin Kozbial, Sandra Beinhardt, M. Trauner, and C Freissmuth

Subjects
medicine.medical_specialty, Add on treatment, Primary (chemistry), Hepatology, medicine.drug_class, business.industry, Internal medicine, medicine, Fibrate, business, Gastroenterology, Ursodeoxycholic acid, medicine.drug
Published
2016

215. Interferon-Free Treatment with Sofosbuvir Plus Daclatasvir Achieves Sustained Virologic Response in 100% of Difficult-To-Treat HIV/HCV-Coinfected Patients and Decreases Liver Stiffness

Author

M. Mandorfer, on behalf of Vienna HIV & Liver Study Group, P. Schwabl, S. Steiner, B. Scheiner, D. Chromy, T. Bucsics, A.F. Staettermayer, M.C. Aichelburg, K. Grabmeier-Pfistershammer, M. Trauner, T. Reiberger, and M. Peck-Radosavljevic

Subjects
Daclatasvir, Hepatology, Sofosbuvir, business.industry, Liver stiffness, Interferon free, Virologic response, Medicine, business, Virology, medicine.drug
Published
2016

216. Heterozygous carriage of the alpha1-antitrypsin Z variant rs28929474 predisposes to the development of cirrhosis in the presence of alcohol misuse and non-alcohol-related fatty liver disease

Author

M. Trauner, Thomas Berg, Elmar Aigner, Marsha Y. Morgan, Jochen Hampe, Janett Fischer, I. Spivak, Bence Sipos, Pavel Strnad, Hans-Dieter Nischalke, Mattias Mandorfer, Jonas Rosendahl, Stephan Buch, Christian Datz, Sabina Janciauskiene, Clemens Schafmayer, Felix Stickel, Karim Hamesch, and Christian Trautwein

Subjects
medicine.medical_specialty, Pathology, Cirrhosis, Hepatology, business.industry, 05 social sciences, Fatty liver, Alcohol, Disease, medicine.disease, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Carriage, chemistry, Internal medicine, 0502 economics and business, medicine, 050211 marketing, 030211 gastroenterology & hepatology, business
Published
2017

217. A prospective study to evaluate the efficacy of a standardized low calorie diet according to PNPLA3 genotype in patients with Non Alcoholic Fatty Liver Disease (NAFLD) – 2 months data (interim analysis)

Author

R Winker, Helmuth Haslacher, Peter Ferenci, M. Trauner, Harald Hofer, B Meyer, S. Nistler, Thomas-Matthias Scherzer, C Rabitsch, B Mehl, and M Teufelhart

Subjects
medicine.medical_specialty, Hepatology, business.industry, Fatty liver, Non alcoholic, Disease, medicine.disease, Interim analysis, Gastroenterology, Internal medicine, Low calorie diet, Genotype, medicine, In patient, business, Prospective cohort study
Published
2017

218. Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2 -/- mice by modulating fecal bile acid composition and signaling

Author

Hanns-Ulrich Marschall, Marcus Ståhlman, Tatjana Stojakovic, Nadja Leditznig, M. Trauner, G Paumgartner, Annika Wahlström, Emina Halilbasic, and Christiane Fuchs

Subjects
0301 basic medicine, medicine.medical_specialty, Hepatology, Bile acid, medicine.drug_class, Chemistry, Bile duct, Colesevelam, Gastroenterology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Internal medicine, medicine, 030211 gastroenterology & hepatology, Composition (visual arts), Feces, medicine.drug
Published
2017

219. Soluble Axl identifies patients at higher risk for hepatocellular carcinoma development: results from a large scale multicenter analysis

Author

H. Toyoda, C. Lackner, Patrick Starlinger, Judith Stift, Christine Brostjan, Rudolf E. Stauber, Karl-Heinz Weiss, Katharina Staufer, Takashi Kumada, Heike Bantel, Thomas Gruenberger, M. Trauner, Daniel Gotthardt, Wolfgang Mikulits, Thomas S. Weiss, Peter Rauch, Petra Klöters-Plachky, Heidemarie Huber, Hannelore Pock, Mirko Dengler, and Toshifumi Tada

Subjects
Oncology, medicine.medical_specialty, Pathology, Hepatology, Scale (ratio), business.industry, Internal medicine, Hepatocellular carcinoma, medicine, medicine.disease, business
Published
2017

224. NorUDCA improves liver injury and metabolic situation in mouse models of obesity and steatosis

Author

W.E. Haubensak, J. Grießner, M. Trauner, Malte C. Rühlemann, E. Einwallner, Tatjana Stojakovic, Thierry Claudel, Henkjan J. Verkade, Onne A H O Ronda, Femke-Anouska Heinsen, Hubert Scharnagl, and Daniel Steinacher

Subjects
Liver injury, medicine.medical_specialty, Hepatology, business.industry, Internal medicine, medicine, Steatosis, medicine.disease, business, Gastroenterology, Obesity
Published
2017

228. O094 : The presence of echocardiographic abnormalities increases mortality in patients with spontaneous bacterial peritonitis

Author

Markus Peck-Radosavljevic, Thomas Horvatits, Mattias Mandorfer, Georg Goliasch, Arnulf Ferlitsch, W. Sieghart, Simona Bota, M. Trauner, Valentin Fuhrmann, Philipp Schwabl, Thomas Reiberger, and N. Pfisterer

Subjects
medicine.medical_specialty, Spontaneous bacterial peritonitis, Hepatology, business.industry, Internal medicine, medicine, In patient, medicine.disease, business, Gastroenterology
Published
2015

229. LP38 : Efficacy and safety of IFN-free antiviral therapy in patients with HCV recurrence after liver transplantation: real-life experience from austria

Author

Markus Peck-Radosavljevic, Peter Ferenci, Wolfgang Vogel, Ivo Graziadei, Rudolf E. Stauber, C Freissmuth, Katharina Staufer, R Stern, S Hametner, Karin Kozbial, M. Trauner, Andreas Maieron, R Al-Zoairy, Michael Strasser, Harald Hofer, Sandra Beinhardt, and Heinz Zoller

Subjects
Oncology, medicine.medical_specialty, Hepatology, business.industry, medicine.medical_treatment, Antiviral therapy, Hcv recurrence, Liver transplantation, Ifn free, Surgery, Internal medicine, medicine, In patient, business
Published
2015

232. Risk factors for development and mortality of spontaneous bacterial peritonitis in cirrhotic patients with ascites

Author

Mattias Mandorfer, M. Trauner, A Blacky, AM Hirschl, T Bucsics, Thomas Reiberger, K Soucek, Philipp Schwabl, Markus Peck-Radosavljevic, and Arnulf Ferlitsch

Subjects
medicine.medical_specialty, Pathology, Spontaneous bacterial peritonitis, business.industry, Internal medicine, Ascites, Gastroenterology, medicine, medicine.symptom, medicine.disease, business
Published
2013

234. A multi-center retrospective study of photodynamic therapy with polyhematoporphyrin for malignant biliary obstruction: results of 76 consecutive applications

Author

M. Trauner, Wolfgang Plieschnegger, I. Hinterberger, L Booz, Werner Dolak, Peter Knoflach, F Siebert, M Wasilewski, B Hellmich, Michael Gschwantler, B Stadler, M Fleischer, and Andreas Püspök

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Gastroenterology, medicine, Photodynamic therapy, Center (algebra and category theory), Retrospective cohort study, Radiology, business
Published
2013

235. High-field MR-Spectroscopy (MRS) allows novel insights in alterd hepatic lipid and energy metabolism in NAFLD with potential distinction of NASH and advanced fibrosis

Author

Emina Halilbasic, Martin Gajdošík, M. Trauner, J Stift, Christian Kienbacher, Ladislav Valkovič, Ahmed Ba-Ssalamah, Harald Hofer, Marek Chmelik, S. Trattnig, P Munda, Martin Krššák, Fritz Wrba, Peter Ferenci, and Stefan Traussnigg

Subjects
High field mr, Pathology, medicine.medical_specialty, Endocrinology, Hepatic lipid, business.industry, Internal medicine, Gastroenterology, medicine, Energy metabolism, business, Advanced fibrosis
Published
2013

241. Adalimumab (ADA) and Infliximab (IFX) therapy during pregnancy in IBD: a prospective assessment of outcome, safety and cord blood levels

Author

H. Vogelsang, Pavol Papay, Christian Primas, A Mikultis, M. Trauner, C. Gratzer, Gottfried Novacek, Stefan Traussnigg, Alexander Eser, S. Angelberger, Clemens Dejaco, and Walter Reinisch

Subjects
medicine.medical_specialty, Pregnancy, business.industry, Internal medicine, Cord blood, Gastroenterology, medicine, Adalimumab, medicine.disease, business, Infliximab, Surgery, medicine.drug
Published
2013

243. High Prevalence of Anti-Saccharomyces Cerevisiae Antibodies in Cystic Fibrosis Patients after Lung Transplantation

Author

S. Harm, M. Trauner, Emina Halilbasic, H. Vogelsang, P. Jaksch, W. Klepetko, C. Lichtenberger, Lili Kazemi-Shirazi, A. Niculescu, and Katharina Staufer

Subjects
High prevalence, biology, business.industry, medicine.medical_treatment, Saccharomyces cerevisiae, Gastroenterology, biology.organism_classification, medicine.disease, Cystic fibrosis, Immunology, medicine, biology.protein, Lung transplantation, Antibody, business
Published
2013

247. Durable response in the markers of cholestasis through 18 months of open-label extension with obeticholic acid in primary biliary cholangitis

Author

Catherine Vincent, A. Floreani, Frederik Nevens, Jaroslaw Regula, Christopher L. Bowlus, Leigh MacConell, P. Andreone, Velimir A. Luketic, Simon Hohenester, J.P.H. Drenth, David Shapiro, B.E. Hansen, Pietro Invernizzi, M. Trauner, Victor Vargas, Mitchell L. Shiffman, Paul J. Pockros, Simone I. Strasser, K.J. van Erpecum, Giuseppe Mazzella, and T. Marmon

Subjects
medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Obeticholic acid, medicine.disease, chemistry.chemical_compound, Cholestasis, chemistry, Internal medicine, medicine, Open label, business
Published
2016

248. Su1722 Risk Factors Cannot Explain the Sex Specific Difference in Detection Rates of Colorectal Adenomas and Advanced Adenomas

Author

Monika Ferlitsch, Irina Gessl, Philip Jeschek, Martha Britto-Arias, Arnulf Ferlitsch, Elisabeth Fasching, Bernd Jilma, Daniela Sallinger, Elisabeth Waldmann, Michael Kundi, Georg Heinze, and M. Trauner

Subjects
Oncology, medicine.medical_specialty, Advanced adenomas, business.industry, Internal medicine, Gastroenterology, medicine, Radiology, Nuclear Medicine and imaging, Detection rate, business, Sex specific
Published
2016

249. Su1255 Enteroscopy With a Confocal Laser Endomicroscope Detects Early Changes Related to Acute Gastrointestinal Graft-Versus-Host Disease in the Jejunum - A Prospective Study Involving 23 Consecutive Patients After Hematopoietic Stem Cell Transplantation

Author

Michael Häfner, M. Trauner, Werner Dolak, Barbara Tribl, Maximilian Schöniger-Hekele, Andreas Püspök, Yumiko Kamogawa, Werner Rabitsch, and Peter Kalhs

Subjects
Enteroscopy, medicine.medical_specialty, Pathology, business.industry, medicine.medical_treatment, Confocal, Gastroenterology, Hematopoietic stem cell transplantation, medicine.disease, Jejunum, Graft-versus-host disease, medicine.anatomical_structure, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Prospective cohort study, business
Published
2016

250. Tu1042 Cecal Intubation Rate Correlates With Adenoma Detection Rate But Has No Impact on Advanced Adenoma Detection Rate

Author

Philip Jeschek, Irina Gessl, Elisabeth Waldmann, M. Trauner, Monika Ferlitsch, Daniela Sallinger, Martha Britto-Arias, B Majcher, and A Dokladanska

Subjects
medicine.medical_specialty, Adenoma, business.industry, General surgery, Internal medicine, Gastroenterology, medicine, Cecal intubation, Radiology, Nuclear Medicine and imaging, Detection rate, business, medicine.disease
Published
2016

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