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1,233 results on '"Lee, Hye Jeong"'

204. Effect of chitinase‐3‐like protein 1 on glucose metabolism: In vitro skeletal muscle and human genetic association study

Author

Kwak, So‐Young, primary, Seo, Il Hyeok, additional, Chung, InHyeok, additional, Kim, Shin Ae, additional, Lee, Jung Ok, additional, Lee, Hye Jeong, additional, Kim, Sung Eun, additional, Han, Jeong Ah, additional, Kang, Min Ju, additional, Kim, Su Jin, additional, Lim, Soo, additional, Kim, Kyoung Min, additional, Chung, Ji Hyung, additional, Lim, Eunice, additional, Hwang, Jong‐Ik, additional, Kim, Hyeon Soo, additional, and Shin, Min‐Jeong, additional

Published
2020
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208. Cardiotoxicity evaluation using magnetic resonance imaging in breast Cancer patients (CareBest): study protocol for a prospective trial

Author

Hong, Yoo Jin, primary, Kim, Gun Min, additional, Han, Kyunghwa, additional, Kim, Pan Ki, additional, Lee, Su An, additional, An, Eunkyung, additional, Lee, Ji Yeon, additional, Lee, Hye-Jeong, additional, Hur, Jin, additional, Kim, Young Jin, additional, Kim, Min Jung, additional, and Choi, Byoung Wook, additional

Published
2020
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214. Tunable in-plane thermal conductivity of a single PEDOT:PSS nanotube

Author

Lee, Hye Jeong, primary, Shin, Hosun, additional, Anoop, Gopinathan, additional, Yoo, Tae Jin, additional, So, Soonsung, additional, Ryu, Jeongjae, additional, Lee, Byoung Hun, additional, Song, Jae Yong, additional, Lee, Eunji, additional, Hong, Seungbum, additional, Lee, Joo-Hyoung, additional, and Jo, Ji Young, additional

Published
2020
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215. Cohort Profile: Firefighter Research on the Enhancement of Safety and Health (FRESH), a Prospective Cohort Study on Korean Firefighters

Author

Kim, Yun Tae, primary, Kim, Woo Jin, additional, Choi, Jee Eun, additional, Bae, Mun-joo, additional, Jang, Heeseon, additional, Lee, Chan Joo, additional, Lee, Hye-Jeong, additional, Im, Dong Jin, additional, Ye, Byoung Seok, additional, Kim, Mi-Ji, additional, Jeong, Yeoju, additional, Oh, Sung Soo, additional, Jung, Young-Chul, additional, Kang, Eun Seok, additional, Park, Sungha, additional, Lee, Seung Koo, additional, Park, Ki Soo, additional, Koh, Sang Baek, additional, and Kim, Changsoo, additional

Published
2020
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223. Plant‐derived human recombinant growth factors and serum albumin maintain stemness of human‐induced pluripotent stem cells.

Author

Lee, Yukyeong, Lee, Hye Jeong, Ham, Seokbeom, Jeong, Dahee, Lee, Minseong, Lee, Uiil, Lee, Myungseok, Kwon, Tae‐Ho, and Ko, Kinarm

Subjects
*PLURIPOTENT stem cells, *GROWTH factors, *STEM cell culture, *FIBROBLAST growth factor 2, *EPIDERMAL growth factor, *FIBROBLAST growth factors, *REGENERATION (Biology)
Abstract

Stem cells are an important therapeutic source for recovery and regeneration, as their ability of self‐renewal and differentiation offers an unlimited supply of highly specialized cells for therapeutic transplantation. Growth factors and serum are essential for maintaining the characteristics of stem cells in culture and for inducing differentiation. Because growth factors are produced mainly in bacterial (Escherichia coli) or animal cells, the use of such growth factors raises safety concerns that need to be resolved for the commercialization of stem cell therapeutics. To overcome this problem, studies on proteins produced in plants have been conducted. Here, we describe the functions of plant‐derived fibroblast growth factor 2 (FGF2) and human serum albumin in the maintenance and differentiation of human‐induced pluripotent stem cells (hiPSCs). Plant‐derived FGF2 and human epidermal growth factor EGF were able to differentiate hiPSCs into neural stem cells (NSCs). These NSCs could differentiate into neuronal and glial cells. Our results imply that culturing stem cells in animal‐free culture medium, which is composed of plant‐derived proteins, would facilitate stem cell application research, for example, for cell therapy, by reducing contamination risk. [ABSTRACT FROM AUTHOR]

Published
2022
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237. Additional diagnostic value of tumor markers in cytological fluid for diagnosis of non-small-cell lung cancer

Author

Hur Jin, Lee Hye-Jeong, Nam Ji, Kim Young, Hong Yoo, Kim Hee, Kim Se, Chang Joon, Kim Joo-Hang, Chung Kyung, Lee Hye, and Choi Byoung

Subjects
Cytokeratin 19 fragments (CYFRA 21–1), Carcinoembryonic antigen (CEA), Squamous cell carcinoma antigen (SCC), Needle aspiration biopsy (NAB), Tumor marker, Cytological fluid, Non-small cell lung cancer (NSCLC), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Cytological fluid from a needle aspiration biopsy (NAB) is obtained directly from tumor tissue, therefore many biomarker candidates will be present in high concentrations. The aim of this study was to prospectively assess and validate the tumor markers CYFRA 21–1, CEA, and SCC in cytological fluid obtained from NAB samples to determine if they improved the performance of NAB for diagnosing non-small cell lung cancer (NSCLC). Methods A total of 194 patients (M:F = 128:66, mean age 63.7 years) with suspected malignant pulmonary lesions were prospectively enrolled and underwent percutaneous NAB. Levels of CYFRA 21–1, CEA, and SCC were measured by immunoassay in serum and cytological fluid obtained during aspiration biopsy. Cut-off values to determined malignancy were 3.3 ng/mL in serum and 15.7 ng/mL in cytological fluid for CYFRA 21–1, 5 ng/mL and 0.6 ng/mL for CEA, and 2 ng/mL and 0.86 ng/mL for SCC. Results Of 194 patients, 139 patients (71.6%) had NSCLC and 55 (28.4%) had benign lesions. Sensitivity increased significantly for NAB combined with cytological tumor markers compared with NAB alone (CYFRA 21–1: 95% versus 83.5%, p < 0.001, CEA: 92.1% versus 83.5%, p = 0.002, SCC: 91.4% versus 83.5%, p = 0.003). Accuracy improved significantly for NAB combined with cytological CYFRA 21–1 compared with NAB alone (95.9% versus 88.1%, p < 0.001). The area under curve (AUC) of NAB with cytological CYFRA 21–1 was significantly larger than for NAB alone (0.966 versus 0.917, p = 0.009). Conclusion Of the tested tumor markers, cytological fluid measurements of CYFRA 21–1 improved the diagnostic performance of NAB for NSCLC.

Published
2012
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238. Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: its assessment by cardiac magnetic resonance

Author

Kim Hyun, Kim Kwang, Lee Hye-Jeong, Yu Hee, Moon Jae, Kang Eun, Cha Bong, Lee Hyun, Lee Byung-Wan, and Kim Young

Subjects
Epicardial adipose tissue, Cardiovascular magnetic resonance, Silent ischemia, Coronary artery stenosis, Type 2 diabetes, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background We used cardiovascular magnetic resonance (CMR) to investigate the association between epicardial adipose tissue (EAT) thickness and silent myocardial ischemia, as well as coronary artery stenosis, in asymptomatic type 2 diabetic patients. Methods The study included 100 type 2 diabetic subjects (51 male and 49 female; mean age: 56 ± 7 years). Silent myocardial ischemia, as determined by CMR, was defined as evidence of inducible ischemia or myocardial infarction. Signal reduction or stenosis of ≥ 50% in the vessel diameter was used as the criteria for significant coronary artery stenosis on coronary magnetic resonance (MR) angiography. Results EAT thickness was positively correlated with body mass index (BMI), waist-to-hip ratio, systolic blood pressure, postprandial glucose, fasting/postprandial triglyceride (TG), serum glycated hemoglobin (HbA1c) level, and homeostasis model assessment of insulin resistance (HOMA-IR) score. Significant coronary artery stenosis was found in 24 patients, while 14 patients had silent myocardial ischemia in CMR (1 with silent myocardial infarction, 11 with inducible ischemia, and 2 with both). EAT thickness was greater in patients who had coronary artery stenosis (13.0 ± 2.6 mm vs. 11.5 ± 2.1 mm, p = 0.01), but did not differ between the subjects with or without silent myocardial ischemia on CMR images (12.8 ± 2.1 vs. 11.7 ± 2.3 mm, p = 0.11). Multivariate logistic regression analysis indicated that EAT thickness was an independent indicator for significant coronary artery stenosis after adjusting for traditional risk factors (OR 1.403, p = 0.026). Conclusions Increased EAT thickness assessed by CMR is an independent risk factor for significant coronary artery stenosis in asymptomatic type 2 diabetes. However, EAT thickness was not associated with silent myocardial ischemia.

Published
2012
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240. ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways

Author

Lee, Hye Jeong, primary, Moon, Jiyoung, additional, Chung, InHyeok, additional, Chung, Ji Hyung, additional, Park, Chan, additional, Lee, Jung Ok, additional, Han, Jeong Ah, additional, Kang, Min Ju, additional, Yoo, Eun Hye, additional, Kwak, So‐Young, additional, Jo, Garam, additional, Park, Wonil, additional, Park, Jonghoon, additional, Kim, Kyoung Min, additional, Lim, Soo, additional, Ngoei, Kevin R. W., additional, Ling, Naomi X. Y., additional, Oakhill, Jonathan S., additional, Galic, Sandra, additional, Murray‐Segal, Lisa, additional, Kemp, Bruce E., additional, Mantzoros, Christos S., additional, Krauss, Ronald M., additional, Shin, Min‐Jeong, additional, and Kim, Hyeon Soo, additional

Published
2019
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246. Structural Recovery of Highly Oxidized Single-Walled Carbon Nanotubes Fabricated by Kneading and Electrochemical Applications

Author

Han, Joong Tark, primary, Cho, Joon Young, additional, Kim, Jung Hoon, additional, Jang, Jeong In, additional, Kim, Jun Suk, additional, Lee, Hye Jeong, additional, Park, Jong Hwan, additional, Chae, Ji Su, additional, Roh, Kwang Chul, additional, Lee, Wonki, additional, Hwang, Jun Yeon, additional, Kim, Ho Young, additional, Jeong, Hee Jin, additional, Jeong, Seung Yol, additional, and Lee, Geon-Woong, additional

Published
2019
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247. LIF, a Novel Myokine, Protects Against Amyloid-Beta-Induced Neurotoxicity via Akt-Mediated Autophagy Signaling in Hippocampal Cells

Author

Lee, Hye Jeong, primary, Lee, Jung Ok, additional, Lee, Yong Woo, additional, Kim, Shin Ae, additional, Seo, Il Hyeok, additional, Han, Jeong Ah, additional, Kang, Min Ju, additional, Kim, Su Jin, additional, Cho, Yun-Ho, additional, Park, Joong-Jean, additional, Choi, Jong-Il, additional, Park, Sun Hwa, additional, and Kim, Hyeon Soo, additional

Published
2019
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