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1,349 results on '"Kim, Soo Wan"'

205. Intensity of statin therapy and renal outcome in chronic kidney disease: Results from the Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease

Author

Jhee, Jong Hyun, primary, Joo, Young Su, additional, Park, Jung Tak, additional, Yoo, Tae-Hyun, additional, Park, Sue Kyung, additional, Jung, Ji Yong, additional, Kim, Soo Wan, additional, Oh, Yun Kyu, additional, Oh, Kook-Hwan, additional, Kang, Shin-Wook, additional, Choi, Kyu Hun, additional, Ahn, Curie, additional, and Han, Seung Hyeok, additional

Published
2020
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209. Alcohol Consumption and Progression of Chronic Kidney Disease: Results From the Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease

Author

Joo, Young Su, primary, Koh, Heebyung, additional, Nam, Ki Heon, additional, Lee, Sangmi, additional, Kim, Joohwan, additional, Lee, Changhyun, additional, Yun, Hae-Ryong, additional, Park, Jung Tak, additional, Kang, Ea Wha, additional, Chang, Tae Ik, additional, Yoo, Tae-Hyun, additional, Oh, Kook-Hwan, additional, Chae, Dong Wan, additional, Lee, Kyu-Beck, additional, Kim, Soo Wan, additional, Lee, Joongyub, additional, Kang, Shin-Wook, additional, Choi, Kyu Hun, additional, Ahn, Curie, additional, and Han, Seung Hyeok, additional

Published
2020
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216. Urinary chloride concentration and progression of chronic kidney disease: results from the KoreaN cohort study for Outcomes in patients With Chronic Kidney Disease

Author

Joo, Young Su, primary, Kim, Jinseok, additional, Park, Cheol Ho, additional, Yun, Hae-Ryong, additional, Park, Jung Tak, additional, Chang, Tae Ik, additional, Yoo, Tae-Hyun, additional, Sung, Su-Ah, additional, Lee, Joongyub, additional, Oh, Kook-Hwan, additional, Kim, Soo Wan, additional, Kang, Shin-Wook, additional, Choi, Kyu Hun, additional, Ahn, Curie, additional, and Han, Seung Hyeok, additional

Published
2019
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217. Efficacy and Safety of CKD-11101 (Proposed Biosimilar of Darbepoetin-Alfa) Compared with Darbepoetin-Alfa in Patients on Hemodialysis: A Randomized, Double-Blinded, Parallel-Group Phase III Study

Author

Kim, Yaerim, primary, Park, Su-Kil, additional, Cho, Won Yong, additional, Joo, Kwon Wook, additional, Shin, Sug Kyun, additional, Kim, Dae Joong, additional, Kim, Yong-Lim, additional, Son, Sung Hyun, additional, Chung, Wookyung, additional, Lee, Kwang Young, additional, Park, Sung Kwang, additional, Kim, Joong Kyung, additional, Kim, Soo Wan, additional, Kang, Duk-Hee, additional, Kim, Jin Kuk, additional, Jeon, Jin Seok, additional, Lee, Kang Wook, additional, Lee, Chang Hwa, additional, Oh, Dong-Jin, additional, An, Won Suk, additional, Lee, Jong Soo, additional, Kang, Gun Woo, additional, Do, Jun-young, additional, Lee, Jung Pyo, additional, and Jin, Kyubok, additional

Published
2019
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247. Urinary chloride concentration and progression of chronic kidney disease: results from the KoreaN cohort study for Outcomes in patients With Chronic Kidney Disease.

Author

Joo, Young Su, Kim, Jinseok, Park, Cheol Ho, Yun, Hae-Ryong, Park, Jung Tak, Chang, Tae Ik, Yoo, Tae-Hyun, Sung, Su-Ah, Lee, Joongyub, Oh, Kook-Hwan, Kim, Soo Wan, Kang, Shin-Wook, Choi, Kyu Hun, Ahn, Curie, and Han, Seung Hyeok

Subjects
CHRONIC kidney failure, CHRONICALLY ill, KIDNEY tubules, CHLORIDES, COHORT analysis
Abstract

Background Urinary chloride is regulated by kidney transport channels, and high urinary chloride concentration in the distal tubules can trigger tubuloglomerular feedback. However, little attention has been paid to urinary chloride as a biomarker of clinical outcomes. Here, we studied the relationship between urinary chloride concentration and chronic kidney disease (CKD) progression. Methods We included 2086 participants with CKD from the KoreaN cohort study for Outcomes in patients With Chronic Kidney Disease. Patients were categorized into three groups, according to baseline urinary chloride concentration tertiles. The study endpoint was a composite of ≥50% decrease in estimated glomerular filtration rate from baseline values, or end-stage kidney disease. Results During a median follow-up period of 3.4 years (7452 person-years), 565 participants reached the primary endpoint. There was a higher rate of CKD progression events in the lowest and middle tertiles than in the highest tertile. Compared with the lowest tertile, the highest tertile was associated with 33% [95% confidence interval (CI) 0.49–0.90] lower risk for the primary outcome in a cause-specific hazard model after adjustment for confounding variables. In addition, for every 25 mEq/L increase in urinary chloride concentration, there was 11% (95% CI 0.83–0.96) lower risk for CKD progression. This association was consistent in a time-varying model. Urinary chloride concentration correlated well with tubule function and kidney injury markers, and its predictive performance for CKD progression was comparable to that of these markers. Conclusions In this hypothesis-generating study, low urinary chloride concentration was associated with a higher risk for CKD progression. [ABSTRACT FROM AUTHOR]

Published
2021
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