201. Progress towards elimination of rubella and congenital rubella syndrome in Singapore: Are we there yet?
- Author
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L. W. Ang and Y.X. Chua
- Subjects
Microbiology (medical) ,Congenital rubella syndrome ,Pediatrics ,medicine.medical_specialty ,business.industry ,Economic shortage ,General Medicine ,medicine.disease ,Intradermal vaccination ,Rubella ,Virology ,lcsh:Infectious and parasitic diseases ,Serology ,Infectious Diseases ,Immunity ,Cohort ,medicine ,lcsh:RC109-216 ,Rabies ,business - Abstract
Methods M 83,3% (734) of subjects had a long-lasting immunity whit RFFIT above 10 IU/ml; 96.6% (851) of subjects had a RFFIT above 3.0 IU/ml. We observed a delay in days of serology testing (mean=145 (SD 6,3/range 7–1603). Conclusion: The Classical (day 0, 7, 28, 365) Intradermal PreexposureVaccination is Immunogenic andVery Promising to tackle the problem of Volume Shortage in Biologicals worldwide. Neutralizing Antibodies after four intradermal rabies injections are considered to be boostable in 100% of cases and protective in 96,6% of subjects in this largest cohort of intradermal vaccination worldwide.
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