201. Evaluation of right and left ventricular function using pulsed-wave tissue Doppler echocardiography in patients with subclinical hypothyroidism
- Author
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Yüksel Aksoy, N. Turan, Ergun Topal, Ibrahim Sahin, Feridun Kosar, and Cagatay Taskapan
- Subjects
Adult ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Diastole ,Thyrotropin ,Ventricular Function, Left ,Endocrinology ,Tissue Doppler echocardiography ,Hypothyroidism ,Internal medicine ,medicine ,Humans ,In patient ,Endothelial dysfunction ,Isovolumetric contraction ,Subclinical infection ,Echocardiography, Doppler, Pulsed ,Ventricular function ,business.industry ,Heart ,medicine.disease ,Thyroxine ,medicine.anatomical_structure ,Ventricle ,Cardiology ,Ventricular Function, Right ,Triiodothyronine ,Female ,business - Abstract
Previous studies showed that subclinical hypothyroidism (SH) was associated with cardiovascular disorders, such as endothelial dysfunction, atherosclerosis and myocardial dysfunction. Only one study investigated left ventricular (LV) function using pulsed tissue Doppler echocardiography (TDE) in patients with SH. However, no study has used this technique in the identification of right ventricular (RV) function in these patients. We aimed to investigate the effect of SH on RV and LV function using TDE technique. The present study included 36 newly diagnosed SH patients and 28 healthy controls. For each subjects, serum free T3 (FT3), free T4 (FT4), total T3 (TT3), total T4 (TT4), TSH, peroxidase antibody (TPOab) and thyroglobulin antibody (TGab) levels were measured, and standard echocardiography and TDE were performed. In patients with SH, TSH levels were significantly higher, and TPOab and TGab levels were significantly higher when compared to healthy controls. TDE showed that the patients had significantly lower early diastolic mitral and tricuspid annular velocity (Ea) and early/late (Ea/Aa) diastolic mitral and tricuspid annular velocity ratio (p
- Published
- 2005