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201. Nasal symptoms, epithelial injury and neurogenic inflammation in elite swimmers

Author

Steelant, Brecht, primary, Hox, Valerie, additional, Van Gerven, Laura, additional, Dilissen, Ellen, additional, Dekimpe, Emily, additional, Kasran, Ahmad, additional, Aertgeerts, Sven, additional, Van Belle, Vincent, additional, Peers, Koen, additional, Dupont, Lieven J., additional, Hellings, Peter W., additional, Bullens, Dominique M., additional, and Seyes, Sven F., additional

Published
2018
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202. Rhinology Future Debates 2017 by EUFOREA: Novel treatments and surgical solutions in rhinology

Author

Fokkens, Wytske J., primary, Pugin, Benoit, additional, Bachert, Claus, additional, Bousquet, Jean, additional, Joos, Guy, additional, Louis, Renaud, additional, Pilette, Charles, additional, Pfaar, Oliver, additional, Price, David, additional, Prokopakis, Emmanuel, additional, Scadding, Glenis, additional, Strzembosz, Agnieszka, additional, Weilandt, Anders, additional, Seys, Sven, additional, and Hellings, Peter W., additional

Published
2018
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204. Atopic Comorbidities and Biomarkers of Type 2 Inflammation in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) Who Failed Intranasal Corticosteroids

Author

Bachert, Claus, primary, Hellings, Peter W., additional, Mullol, Joaquim, additional, Naclerio, Robert M., additional, Hamilos, Daniel L., additional, Gevaert, Philippe, additional, Zhang, Dongui, additional, Khan, Asif, additional, Fan, Chunpeng, additional, Amin, Nikhil, additional, Hamilton, Jennifer D., additional, Swanson, Brian N., additional, Pirozzi, Gianluca, additional, Graham, Neil M.H., additional, and Mannent, Leda, additional

Published
2018
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206. European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: report of the European Union Parliament Summit (29 March 2017)

Author

Hellings, Peter W., primary, Borrelli, David, additional, Pietikainen, Sirpa, additional, Agache, Ioana, additional, Akdis, Cezmi, additional, Bachert, Claus, additional, Bewick, Michael, additional, Botjes, Erna, additional, Constantinidis, Jannis, additional, Fokkens, Wytske, additional, Haahtela, Tari, additional, Hopkins, Claire, additional, Illario, Maddalena, additional, Joos, Guy, additional, Lund, Valerie, additional, Muraro, Antonella, additional, Pugin, Benoit, additional, Seys, Sven, additional, Somekh, David, additional, Stjärne, Pär, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, and Bousquet, Jean, additional

Published
2017
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207. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis : A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author

Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, Smit, HA, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, and Smit, HA

Published
2017

208. Allergen immunotherapy for allergic rhinoconjunctivitis : A systematic overview of systematic reviews

Author

Nurmatov, Ulugbek, Dhami, Sangeeta, Arasi, Stefania, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Durham, Stephen, van Wijk, Roy Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Larenas-Linnemann, Desiree, Lin, Sandra Y, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, Sheikh, Aziz, Nurmatov, Ulugbek, Dhami, Sangeeta, Arasi, Stefania, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Durham, Stephen, van Wijk, Roy Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Larenas-Linnemann, Desiree, Lin, Sandra Y, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, and Sheikh, Aziz

Published
2017

209. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology.

Author

UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hellings, Peter W, Klimek, Ludger, Cingi, Cemal, Agache, Ioana, Akdis, Cezmi, Bachert, Claus, Bousquet, Jean, Demoly, Pascal, Gevaert, Philippe, Hox, Valérie, Hupin, Cloé, Kalogjera, Livije, Manole, Felicia, Mösges, Ralf, Mullol, Joaquim, Bayar Muluk, Nuray, Muraro, Maria Antonella, Papadopoulos, Nikolaos, Pawankar, Ruby, Rondon, Carmen, Rundenko, Michael, Seys, Sven F, Toskala, Elina, Van Gerven, Laura, Zhang, Luo, Zhang, Nan, Fokkens, Wytske Johanna, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hellings, Peter W, Klimek, Ludger, Cingi, Cemal, Agache, Ioana, Akdis, Cezmi, Bachert, Claus, Bousquet, Jean, Demoly, Pascal, Gevaert, Philippe, Hox, Valérie, Hupin, Cloé, Kalogjera, Livije, Manole, Felicia, Mösges, Ralf, Mullol, Joaquim, Bayar Muluk, Nuray, Muraro, Maria Antonella, Papadopoulos, Nikolaos, Pawankar, Ruby, Rondon, Carmen, Rundenko, Michael, Seys, Sven F, Toskala, Elina, Van Gerven, Laura, Zhang, Luo, Zhang, Nan, and Fokkens, Wytske Johanna

Abstract

This EAACI position paper aims at providing a state-of-the-art overview on nonallergic rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined as nonallergic noninfectious rhinitis (NANIR) patients, often denominated in short as having NAR. NAR is defined as a symptomatic inflammation of the nasal mucosa with the presence of a minimum of two nasal symptoms such as nasal obstruction, rhinorrhea, sneezing, and/or itchy nose, without clinical evidence of endonasal infection and without systemic signs of sensitization to inhalant allergens. Symptoms of NAR may have a wide range of severity and be either continuously present and/or induced by exposure to unspecific triggers, also called nasal hyperresponsiveness (NHR). NHR represents a clinical feature of both AR and NAR patients. NAR involves different subgroups: drug-induced rhinitis, (nonallergic) occupational rhinitis, hormonal rhinitis (including pregnancy rhinitis), gustatory rhinitis, senile rhinitis, and idiopathic rhinitis (IR). NAR should be distinguished from those rhinitis patients with an allergic reaction confined to the nasal mucosa, also called "entopy" or local allergic rhinitis (LAR). We here provide an overview of the current consensus on phenotypes of NAR, recommendations for diagnosis, a treatment algorithm, and defining the unmet needs in this neglected area of research.

Published
2017

210. Multi-morbidities of allergic rhinitis in adults: European Academy of Allergy and Clinical Immunology Task Force Report.

Author

UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, Cingi, Cemal, Gevaert, Philippe, Mösges, Ralf, Rondon, Carmen, Hox, Valérie, Rudenko, Michael, Bayar Muluk, Nuray, Scadding, Glenis Kathleen, Manole, Felicia, Hupin, Cloé, Fokkens, Wytske Johanna, Akdis, Cezmi, Bachert, Claus, Demoly, Pascal, Mullol, Joaquim, Muraro, Maria Antonella, Papadopoulos, Nikolaos, Pawankar, Ruby, Rombaux, Philippe, Toskala, Elina, Kalogjera, Livije, Prokopakis, Manolis, Hellings, Peter W, Bousquet, Jean, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, Cingi, Cemal, Gevaert, Philippe, Mösges, Ralf, Rondon, Carmen, Hox, Valérie, Rudenko, Michael, Bayar Muluk, Nuray, Scadding, Glenis Kathleen, Manole, Felicia, Hupin, Cloé, Fokkens, Wytske Johanna, Akdis, Cezmi, Bachert, Claus, Demoly, Pascal, Mullol, Joaquim, Muraro, Maria Antonella, Papadopoulos, Nikolaos, Pawankar, Ruby, Rombaux, Philippe, Toskala, Elina, Kalogjera, Livije, Prokopakis, Manolis, Hellings, Peter W, and Bousquet, Jean

Abstract

This report has been prepared by the European Academy of Allergy and Clinical Immunology Task Force on Allergic Rhinitis (AR) comorbidities. The aim of this multidisciplinary European consensus document is to highlight the role of multimorbidities in the definition, classification, mechanisms, recommendations for diagnosis and treatment of AR, and to define the needs in this neglected area by a literature review. AR is a systemic allergic disease and is generally associated with numerous multi-morbid disorders, including asthma, eczema, food allergies, eosinophilic oesophagitis (EoE), conjunctivitis, chronic middle ear effusions, rhinosinusitis, adenoid hypertrophy, olfaction disorders, obstructive sleep apnea, disordered sleep and consequent behavioural and educational effects. This report provides up-to-date usable information to: (1) improve the knowledge and skills of allergists, so as to ultimately improve the overall quality of patient care; (2) to increase interest in this area; and (3) to present a unique contribution to the field of upper inflammatory disease.

Published
2017

211. TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells

Author

KU Leuven, Research Foundation - Flanders, Agency for Innovation by Science and Technology (Belgium), Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Commission, Alpizar, Yeranddy A., Boonen, Brett, Sánchez, Alicia, Jung, Carole, López-Requena, Alejandro, Naert, Robbe, Steelant, Brecht, Luyts, Katrien, Plata, Cristina, De Vooght, Vanessa, Vanoirbeek, Jeroen A. J., Meseguer, Víctor M., Voets, Thomas, Álvarez, Julio L., Hellings, Peter W., Hoet, Peter H.M., Nemery, Benoit, Valverde, Miguel A., Talavera, Karel, KU Leuven, Research Foundation - Flanders, Agency for Innovation by Science and Technology (Belgium), Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Commission, Alpizar, Yeranddy A., Boonen, Brett, Sánchez, Alicia, Jung, Carole, López-Requena, Alejandro, Naert, Robbe, Steelant, Brecht, Luyts, Katrien, Plata, Cristina, De Vooght, Vanessa, Vanoirbeek, Jeroen A. J., Meseguer, Víctor M., Voets, Thomas, Álvarez, Julio L., Hellings, Peter W., Hoet, Peter H.M., Nemery, Benoit, Valverde, Miguel A., and Talavera, Karel

Abstract

Lipopolysaccharides (LPS), the major components of the wall of gram-negative bacteria, trigger powerful defensive responses in the airways via mechanisms thought to rely solely on the Toll-like receptor 4 (TLR4) immune pathway. Here we show that airway epithelial cells display an increase in intracellular Ca2+ concentration within seconds of LPS application. This response occurs in a TLR4-independent manner, via activation of the transient receptor potential vanilloid 4 cation channel (TRPV4). We found that TRPV4 mediates immediate LPS-induced increases in ciliary beat frequency and the production of bactericidal nitric oxide. Upon LPS challenge TRPV4-deficient mice display exacerbated ventilatory changes and recruitment of polymorphonuclear leukocytes into the airways. We conclude that LPS-induced activation of TRPV4 triggers signaling mechanisms that operate faster and independently from the canonical TLR4 immune pathway, leading to immediate protective responses such as direct antimicrobial action, increase in airway clearance, and the regulation of the inflammatory innate immune reaction.

Published
2017

212. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis: A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author

Public Health Epidemiologie, Circulatory Health, Child Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, Smit, HA, Public Health Epidemiologie, Circulatory Health, Child Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, and Smit, HA

Published
2017

213. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic overview of systematic reviews

Author

CTI, MS Dermatologie/Allergologie, Infection & Immunity, Nurmatov, Ulugbek, Dhami, Sangeeta, Arasi, Stefania, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Durham, Stephen, van Wijk, Roy Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Larenas-Linnemann, Desiree, Lin, Sandra Y, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, Sheikh, Aziz, CTI, MS Dermatologie/Allergologie, Infection & Immunity, Nurmatov, Ulugbek, Dhami, Sangeeta, Arasi, Stefania, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Durham, Stephen, van Wijk, Roy Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Larenas-Linnemann, Desiree, Lin, Sandra Y, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, and Sheikh, Aziz

Published
2017

214. Erratum to: Allergen immunotherapy for allergic rhinoconjunctivitis: Protocol for a systematic review (Clinical and Translational Allergy (2016) 6 (12) DOI: 10.1186/s13601-016-0099-6)

Author

MS Dermatologie/Allergologie, CDL Celdiagnostiek, Infection & Immunity, CTI, Dhami, Sangeeta, Nurmatov, Ulugbek, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Demoly, Pascal, Durham, Stephen, van Wijk, Ronald Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Linnemann, Desiree Larenas, Lin, Sandra, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, Sheikh, Aziz, MS Dermatologie/Allergologie, CDL Celdiagnostiek, Infection & Immunity, CTI, Dhami, Sangeeta, Nurmatov, Ulugbek, Roberts, Graham, Pfaar, Oliver, Muraro, Antonella, Ansotegui, Ignacio J, Calderon, Moises, Cingi, Cemal, Demoly, Pascal, Durham, Stephen, van Wijk, Ronald Gerth, Halken, Susanne, Hamelmann, Eckard, Hellings, Peter W, Jacobsen, Lars, Knol, Edward, Linnemann, Desiree Larenas, Lin, Sandra, Maggina, Vivian, Oude Elberink, J Hanneke N G, Pajno, Giovanni Battista, Panwankar, Ruby, Pastorello, Elideanna, Pitsios, Constantinos, Rotiroti, Giuseppina, Timmermans, Frans, Tsilochristou, Olympia, Varga, Eva-Maria, Wilkinson, Jamie, Williams, Andrew, Worm, Margitta, Zhang, Luo, and Sheikh, Aziz

Published
2017

215. MACVIA Clinical Decision Algorithm in Allergic Rhinitis in adolescents and adults

Author

Bousquet, Jean, Schünemann, Holger J., Hellings, Peter W., Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl-Christian, Bosnic-Anticevich, Sinthia, Brozek, Jan, Calderon, Moises, Canonica, G. Walter, Casale, Thomas B., Chavannes, Niels H., Cox, Linda, Chrystyn, Henry, Cruz, Alvaro A., Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Philippe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J., Fonseca, Joao, Gonzalez-Diaz, Sandra N., Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas-Linnemann, Désirée, Lodrup Carlsen, Karin C., Meltzer, Eli O., Mullol, Joaquim, Muraro, Antonella, Naclerio, Robert, Palkonen, Susanna, Papadopoulos, Nikolaos G., Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K., Sheikh, Aziz, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Zuberbier, Torsten, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Saint Eloi (CHRU Montpellier), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Departments of Clinical Epidemiology and Biostatistics and Medicine [Ontario], McMaster University [Hamilton, Ontario], Laboratory of clinical immunology, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Kyomed, Upper Airways Research Laboratory, Universiteit Gent = Ghent University (UGENT), Secretary General of the Global Allergy and Asthma European Network (GA2LEN), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Woolcock Institute of Medical Research [Sydney], The University of Sydney, National Heart, Lung, and Blood Institute [Bethesda] (NHLBI), Allergy & Respiratory Diseases Clinic - DIMI, Università degli studi di Genova = University of Genoa (UniGe), Division of Allergy/Immunology, University of South Florida [Tampa] (USF), Department of Public Health and Primary Care [leiden], Leiden University Medical Center (LUMC), Universiteit Leiden-Universiteit Leiden, Department of Medicine [Floride], Nova Southeastern University (NSU), RiRL, ProAR – Nucleo de Excelencia em Asma, Universidade Federal da Bahia (UFBA), Department of Dermatology and Allergy Centre, Odense University Hospital, European Federation of Allergy (EFA), Airways Diseases Patients' Associations, ESIM - Déterminants Sociaux de la Santé et du Recours aux Soins (DS3), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service des Maladies Respiratoires [Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Arnaud de Villeneuve, Laboratoire de Pharmacologie Respiratoire UPRES EA220, UPRES EA 220, Pôle des maladies respiratoires, Hôpital Foch, IMT - MINES ALES (IMT - MINES ALES), Institut Mines-Télécom [Paris] (IMT), Education for Health, Department of Otorhinolaryngology [Amsterdam], Academic Medical Centre [Amsterdam], University of Amsterdam [Amsterdam] (UvA)-University of Amsterdam [Amsterdam] (UvA), Center of Research in Health Technologies and Information Systems (CINTESIS), Universidade do Porto = University of Porto, Universidad Autonoma de Nuevo Leon [Mexique] (UANL), Faculty of the Department of Neurology, University of Washington School of Medicine, Institute of Social Medicine, Epidemiology and Health Economics-Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Division of Internal Medicine, Asthma and Allergy, Medical University of Łódź (MUL)-Barlicki University Hospital, Clínica de Alergia- Asma y Pediatría, Hospital Medica Sur, Department of Paediatrics [Oslo], Oslo University Hospital [Oslo], Allergy & Asthma Medical Group & Research Center, University of California [San Diego] (UC San Diego), University of California (UC)-University of California (UC), Transverse group for research in primary care [Barcelona], Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Women and Child Health, Università degli Studi di Padova = University of Padua (Unipd), Section of Otolaryngology-Head & Neck Surgery (OHNS), University of Chicago, Center for Pediatrics and Child Health, Royal Manchester Children's Hospital, Academic Centre of Primary Care, University of Aberdeen, Allergy and Respiratory Research Group, University of Edinburgh, Department of Prevention of Envinronmental Hazards and Allergology, Medical University of Warsaw - Poland, The Royal National TNE Hospital, University College of London [London] (UCL), Centre for Population Health Sciences, Vilnius University Clinic of Children's Diseases, Dept. of Lung Diseases and Clinical Allergology, University of Turku, Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, (MRC), Guy's Hospital [London], The Institute of Environmental Medicine [Stockholm] (IMM), Karolinska Institutet [Stockholm], Department of Pulmonology, Manisa Celal Bayar University, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), CHU Saint-Eloi, Universiteit Gent = Ghent University [Belgium] (UGENT), University of Genoa (UNIGE), Universidade do Porto, University of California-University of California, and Universita degli Studi di Padova

Subjects
MACVIA-LR, allergic rhinitis, ARIA, clinical decision support system, ICT, conjunctivitis, [SDV.IMM]Life Sciences [q-bio]/Immunology
Abstract

International audience; The selection of pharmacotherapy for patients with allergic rhinitis depends on several factors, including age, prominent symptoms, symptom severity, control of allergic rhinitis, patient preferences and cost. Allergen exposure and resulting symptoms vary and treatment adjustment is required. Clinical decision support systems (CDSS) may be beneficial for the assessment of disease control. Clinical decision support systems should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine the treatment and its step-up or step-down strategy depending on AR control. MACVIA-LR (Fighting chronic diseases for active and healthy ageing) one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (MASK: MACVIA-ARIA Sentinel networK). A clinical decision support system is currently being developed to optimize allergic rhinitis control. An algorithm developed by consensus is presented in this paper. This algorithm should be confirmed by appropriate trials.

Published
2016

217. TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells

Author

Alpizar, Yeranddy A., primary, Boonen, Brett, additional, Sanchez, Alicia, additional, Jung, Carole, additional, López-Requena, Alejandro, additional, Naert, Robbe, additional, Steelant, Brecht, additional, Luyts, Katrien, additional, Plata, Cristina, additional, De Vooght, Vanessa, additional, Vanoirbeek, Jeroen A. J., additional, Meseguer, Victor M., additional, Voets, Thomas, additional, Alvarez, Julio L., additional, Hellings, Peter W., additional, Hoet, Peter H. M., additional, Nemery, Benoit, additional, Valverde, Miguel A., additional, and Talavera, Karel, additional

Published
2017
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218. Resumen ejecutivo de ARIA 2016: vías integradas de atención para la medicina predictiva a lo largo del ciclo de vida en Argentina

Author

Ivancevich, Juan Carlos, primary, Neffen, Hugo, additional, Zermotti, Mario E., additional, Asayag, Estrella, additional, Blua, Ariel, additional, Cicerán, Alberto, additional, Jares, Edgardo J., additional, Lavrut, Alberto J., additional, Máspero, Jorge F., additional, Agache, Ioana, additional, Bachert, Claus, additional, Bedbrook, Anna, additional, Canonica, Giorgio W., additional, Casale, Thomas B., additional, Cruz, Álvaro A., additional, Fokkens, Wytske J., additional, Hellings, Peter W., additional, Samolinski, Boleslaw, additional, and Bousquet, Jean, additional

Published
2017
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220. Abstracts from the 11th Symposium on Experimental Rhinology and Immunology of the Nose (SERIN 2017)

Author

Gracia, Ibon Eguiluz, primary, Rondón, Carmen, additional, Campo, Paloma, additional, Prieto, Ana, additional, Mayorga, Lina, additional, Galindo, Luisa, additional, Molina, Ana, additional, Blanca, Miguel, additional, Torres, Maria Jose, additional, Morikawa, Taiyo, additional, Fukuoka, Ayumi, additional, Matsushita, Kazufumi, additional, Fujieda, Shigeharu, additional, Yoshimoto, Tomohiro, additional, Iwasaki, Naruhito, additional, Smulders, Tamar, additional, Van Egmond, Danielle, additional, Van Drunen, Kees, additional, Van Der Schee, Marc, additional, Beule, Achim Georg, additional, Berings, Margot, additional, Jult, Anton, additional, Vermeulen, Hanne, additional, De Ruyck, Natalie, additional, Derycke, Lara, additional, Ucar, Hakan, additional, Ghekiere, Philip, additional, Temmerman, Robin, additional, Ellis, John, additional, Bachert, Claus, additional, Lambrecht, Bart, additional, Dullaers, Melissa, additional, Gevaert, Philippe, additional, Arasi, Stefania, additional, Perna, Serena, additional, Resch, Yvonne, additional, Lupinek, Christian, additional, Chen, Kuan-Wei, additional, Vrtala, Susanne, additional, Valenta, Rudolf, additional, Matricardi, Paolo Maria, additional, Gonçalves, Ivânia, additional, Jacinto, Tiago, additional, Amaral, Rita, additional, Pereira, Ana M., additional, Araújo, Luís M., additional, Couto, Mariana, additional, Fonseca, João A., additional, Stjarne, Par, additional, Kaulsay, Ranbir, additional, Pohl, Wolfgang, additional, Plaza, Maria Carmen, additional, Prieto, Ana Maria, additional, Mayorga, Cristobalina, additional, Herknerova, Magdalena, additional, Wang, Tengchin, additional, Wu, Chiejun, additional, Kilimajer, Jonathan, additional, Pujols, Laura, additional, Roca-Ferrer, Jordi, additional, Callejas, Borja, additional, Fuentes-Prado, Mireya, additional, Perez-Gonzalez, Maria, additional, Alobid, Isam, additional, Valero, Antonio, additional, Picado, Cesar, additional, Murray, Ruth, additional, Mullol, Joaquim, additional, Steelant, Brecht, additional, Martens, Katleen, additional, Boeckxstaens, Guy, additional, Seys, Sven F., additional, Hellings, Peter W., additional, Biggs, Timothy C., additional, Hayes, Stephen M., additional, Harries, Philip G., additional, Pender, Sylvia, additional, Salib, Rami J., additional, Kim, Jean, additional, Lee, Hyun Sil, additional, Kalogjera, Livije, additional, Vrkic, Nada, additional, Topic, Anita, additional, Tomljenovic, Dejan, additional, Greguric, Tomislav, additional, Radovanovic, Patricija Bankovic, additional, Jund, Rainer, additional, Haimerl, Pascal, additional, Chaker, Adam M., additional, Schober, Yvonne, additional, Schindela, Sonja, additional, Nockher, Andreas, additional, Schmidt-Weber, Carsten B., additional, Bieren, Julia Esser-Von, additional, Ickrath, Pascal, additional, Kleinsasser, Norbert, additional, Beyersdorf, Niklas, additional, Ding, Xin, additional, Hagen, Rudolf, additional, Hackenberg, Stephan, additional, Cangiano, Daniela, additional, Cinetto, Francesco, additional, Brescia, Giuseppe, additional, Marioni, Gino, additional, Zanotti, Claudia, additional, Schiavon, Franco, additional, Padoan, Roberto, additional, Caputo, Ilaria, additional, Neri, Raffaella, additional, Agostini, Carlo, additional, Kim, Ji Heui, additional, Jang, Yong Ju, additional, Lim, Ji Youn, additional, Kim, Sung Hee, additional, Savlevich, Elena, additional, Gaganov, Leonid, additional, Kochnova, Maria, additional, Egorov, Victor, additional, Fok, Jie Shen, additional, Hanif, Tanzeela, additional, Renkonen, Jutta, additional, Joenväärä, Sakari, additional, Kankainen, Matti, additional, Mäkelä, Mika, additional, Kauppi, Paula, additional, Pelkonen, Anna, additional, Mattila, Pirkko, additional, Renkonen, Risto, additional, Toppila-Salmi, Sanna, additional, Holtappels, Gabriele, additional, Lambrecht, Bart N., additional, Blanca-López, Natalia, additional, Gonzalez-Visiedo, Miguel, additional, Jurado, Raquel, additional, and Canto, Gabriela, additional

Published
2017
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224. Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial

Author

Naclerio, Robert M., primary, Hamilos, Daniel L., additional, Ferguson, Berrylin J., additional, Bachert, Claus, additional, Hellings, Peter W., additional, Mullol, Joaquim, additional, Gevaert, Philippe, additional, Zhang, Donghui, additional, Khan, Asif, additional, Fan, Chunpeng, additional, Joish, Vijay N., additional, Amin, Nikhil, additional, Pirozzi, Gianluca, additional, Graham, Neil MH., additional, Staudinger, Heribert W., additional, Grabher, Annette, additional, and Mannent, Leda, additional

Published
2017
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225. Uncontrolled rhinosinusitis

Author

Fokkens, Wystke J., Hellings, Peter W., Akdis, Cezmi A., Agache, Ioana, Amsterdam institute for Infection and Immunity, and Ear, Nose and Throat

Published
2015

227. The GALEN rhinosinusitis cohort: chronic rhinosinusitis with nasal polyps affects health-related quality of life.

Author

Khan, Asif, Thi Minh Thao Huynh, Vandeplas, Griet, Joish, Vijay N., Mannent, Leda P., Tomassen, Peter, van Zele, Thibaut, Cardell, Lars-Olaf, Arebro, Julia, Olze, Heidi, Förster-Ruhrmann, Ulrike, Kowalski, Marek L., Olszewska-Ziąber, Agnieszka, Fokkens, Wytske, van Drunen, Cornelis, Mullol, Joaquim, Alobid, Isam, Hellings, Peter W., Hox, Valérie, and Toskala, Elina

Published
2019
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229. The Global Allergy and Asthma European Network (GALEN) rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps.

Author

Khan, Asif, Vandeplas, Griet, Thi Minh Thao Huynh, Joish, Vijay N., Mannent, Leda, Tomassen, Peter, Van Zele, Thibaut, Cardell, Lars-Olaf, Arebro, Julia, Olze, Heidi, Förster-Ruhrmann, Ulrike, Kowalski, Marek L., Olszewska-Ziąber, Agnieszka, Holtappels, Gabriële, De Ruyck, Natalie, van Drunen, Cornelis, Mullol, Joaquim, Hellings, Peter W., Hox, Valerie, and Toskala, Elina

Published
2019
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230. Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document.

Author

Agache, Ioana, Miller, Rachel, Gern, James E., Hellings, Peter W., Jutel, Marek, Muraro, Antonella, Phipatanakul, Wanda, Quirce, Santiago, and Peden, David

Subjects
ALLERGIES, RHINITIS, ENVIRONMENTAL exposure, ASTHMA, CLINICAL immunology, LIFE spans
Abstract

Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the life span. The exposomic approach provides a risk profile instead of single predictors and thus is particularly applicable to allergic diseases and asthma. Under the PRACTALL collaboration between the European Academy of Allergy and Clinical Immunology (EAACI) and the American Academy of Allergy, Asthma, and Immunology (AAAAI), we evaluated the current concepts and the unmet needs on the role of the exposome in allergic diseases and asthma. [ABSTRACT FROM AUTHOR]

Published
2019
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232. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, Jean, Schünemann, Holger J, Hellings, Peter W, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl-Christian, Bosnic-Anticevich, Sinthia, Brozek, Jan, Calderon, Moises, Canonica, G Walter, Casale, Thomas B, Chavannes, Niels H, Cox, Linda, Chrystyn, Henry, Cruz, Alvaro A, Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J, Fonseca, Joao, Gonzalez-Diaz, Sandra N, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas-Linnemann, Désirée, Lodrup Carlsen, Karin C, Meltzer, Eli O, Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N, Palkonen, Susanna, Papadopoulos, Nikolaos G, Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K, Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, MASK study group*, Bousquet, Jean, Schünemann, Holger J, Hellings, Peter W, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl-Christian, Bosnic-Anticevich, Sinthia, Brozek, Jan, Calderon, Moises, Canonica, G Walter, Casale, Thomas B, Chavannes, Niels H, Cox, Linda, Chrystyn, Henry, Cruz, Alvaro A, Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J, Fonseca, Joao, Gonzalez-Diaz, Sandra N, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas-Linnemann, Désirée, Lodrup Carlsen, Karin C, Meltzer, Eli O, Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N, Palkonen, Susanna, Papadopoulos, Nikolaos G, Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K, Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, and MASK study group*

Published
2016

233. AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation.

Author

UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (MGD) Service de pneumologie, Bousquet, Jean, Barbara, Cristina, Bateman, Eric, Bel, Elisabeth, Bewick, Mike, Chavannes, Niels H, Cruz, Alvaro A, Haahtela, Tari, Hellings, Peter W, Khaltaev, Nikolai, Lodrup Carlsen, Karin, Muraro, Antonella, Cordeiro, Carlos Robalo, Rosado-Pinto, Jose, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, AIRWAYS-ICPs working group, Sibille, Yves, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (MGD) Service de pneumologie, Bousquet, Jean, Barbara, Cristina, Bateman, Eric, Bel, Elisabeth, Bewick, Mike, Chavannes, Niels H, Cruz, Alvaro A, Haahtela, Tari, Hellings, Peter W, Khaltaev, Nikolai, Lodrup Carlsen, Karin, Muraro, Antonella, Cordeiro, Carlos Robalo, Rosado-Pinto, Jose, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, AIRWAYS-ICPs working group, and Sibille, Yves

Published
2016

234. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, Jean J., Schünemann, Holger J., Hellings, Peter W., Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl Christian, Bosnic Anticevitch, Sinthia, Brozek, Jan L., Calderón, Moisés, Canonica, Giorgio Walter, Casale, Thomas B., Chavannes, Niels H., Cox, Linda, Chrystyn, Henry, Cruz, Álvaro A., Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J., Fonseca, Joao A., González Díaz, Sandra Nora, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas Linnemann, Désirée, Lodrup Carlsen, Karin C., Meltzer, E. O., Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N., Palkonen, Susanna, Papadopoulos, Nikolaos G., Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K., Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, Zuberbier, Torsten, Aberer, Werner, Adachi, Mitsuru, Agache, Ioana, Akdis, Cezmi, Akdis, Mubeccel, Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arshad, S. Hasan, Baiardini, Ilaria, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Bel, Elisabeth H., Ben Kheder, Ali, Bennoor, Kazi S., Benson, Michael, Bernstein, David, Michael, Bewick, Thomas, Bieber, Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Camargos, Paulo, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Sarabia, Alfonso Cepeda, Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Ciprandi, Georgio, Cirule, Ieva, Correia de Sousa, Jaime, Costa, David J., Crooks, George, Custovic, Adnan, Dahlen, Sven Erik, Darsow, Ulf, De Blay, Frédéric, De Manuel Keenoy, Esteban, Dedeu, Tony, Deleanu, Diana, Denburg, Judah, Didier, Alain, Dinh Xuan, Anh Tuan, Dokic, Dejan, Douagui, Habib B., Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, Regina, Fink Wagner, Antje H., Fiocchi, Alessandro, Forastiere, Francesco, Gamkrelidze, Amiran, Gemicioğlu, Bilun, Gereda, José E., Gerth van Wijk, Roy, Gotua, Maia, Grisle, Ineta, Guzmán Meléndez, María Antonieta, Heinrich, Joachim, Hellquist Dahl, Birthe, Horak, Friedrich, Howarth, Peter H., Humbert, Marc, Hyland, Michael E., Ivancevich, Juan Carlos, Jares, Edgardo José, Johnston, Sebastian L., Jonquet, Olivier, Joos, Guy, Jung, Ki Suck, Just, Jocelyne, Jutel, Marek, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, Fuat, Keith, Paul K., Khaltaev, Nikolai, Kleine Tebbe, Jorg, Klimek, Ludger, N'Goran, Bernard Koffi, Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Laune, Daniel, Le Thi Tuyet, Lan, Li, Jingmei, Lieberman, Phillipe, Lipworth, Brian J., Renaud, Louis, Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Majer, Ivan, Makela, Mika, Manning, Peter J., Masjedi, Mohamad R., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Mercier, Jacques, Merk, Hans, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Mösges, Ralph, Nadif, Rachel, Namazova Baranova, Leyla, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Niggemann, Bodo, Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Palmer, Stephen, Panzner, Petr, Papi, Alberto, Park, Hae-Sim, Pavord, Ian, Pawankar, Ruby, Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Pohl, Wolfgang, Popov, Todor A., Postma, Dirkje S., Potter, Paul, Poulsen, Lars K., Rabe, Klaus F., Raciborski, Filip, Pontal, Françoise Radier, Reitamo, Sakari, Repka Ramírez, Maria Susana, Robalo Cordeiro, Carlos, Roberts, Graham, Rodenas, Francisco, Rolland, Christine, Rodriguez, Miguel Roman, Romano, Antonino, Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Larry, Rottem, Menachem, Sánchez Borges, Mario, Sastre Dominguez, Joaquim, Schmid Grendelmeier, Peter, Serrano, Eli, Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Strandberg, Timo, Sunyer, Jordi, Thijs, C., Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Van Hage, Marianne, Vandenplas, Olivier, Vezzani, Giorgio, Vichyanond, Pakit, Viegi, Giovanni, Wagenmann, Martin, Wahn, Ulrich, De Yun, Wang, Williams, D. M., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, Bousquet, Jean J., Schünemann, Holger J., Hellings, Peter W., Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl Christian, Bosnic Anticevitch, Sinthia, Brozek, Jan L., Calderón, Moisés, Canonica, Giorgio Walter, Casale, Thomas B., Chavannes, Niels H., Cox, Linda, Chrystyn, Henry, Cruz, Álvaro A., Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J., Fonseca, Joao A., González Díaz, Sandra Nora, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas Linnemann, Désirée, Lodrup Carlsen, Karin C., Meltzer, E. O., Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N., Palkonen, Susanna, Papadopoulos, Nikolaos G., Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K., Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, Zuberbier, Torsten, Aberer, Werner, Adachi, Mitsuru, Agache, Ioana, Akdis, Cezmi, Akdis, Mubeccel, Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arshad, S. Hasan, Baiardini, Ilaria, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Bel, Elisabeth H., Ben Kheder, Ali, Bennoor, Kazi S., Benson, Michael, Bernstein, David, Michael, Bewick, Thomas, Bieber, Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Camargos, Paulo, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Sarabia, Alfonso Cepeda, Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Ciprandi, Georgio, Cirule, Ieva, Correia de Sousa, Jaime, Costa, David J., Crooks, George, Custovic, Adnan, Dahlen, Sven Erik, Darsow, Ulf, De Blay, Frédéric, De Manuel Keenoy, Esteban, Dedeu, Tony, Deleanu, Diana, Denburg, Judah, Didier, Alain, Dinh Xuan, Anh Tuan, Dokic, Dejan, Douagui, Habib B., Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, Regina, Fink Wagner, Antje H., Fiocchi, Alessandro, Forastiere, Francesco, Gamkrelidze, Amiran, Gemicioğlu, Bilun, Gereda, José E., Gerth van Wijk, Roy, Gotua, Maia, Grisle, Ineta, Guzmán Meléndez, María Antonieta, Heinrich, Joachim, Hellquist Dahl, Birthe, Horak, Friedrich, Howarth, Peter H., Humbert, Marc, Hyland, Michael E., Ivancevich, Juan Carlos, Jares, Edgardo José, Johnston, Sebastian L., Jonquet, Olivier, Joos, Guy, Jung, Ki Suck, Just, Jocelyne, Jutel, Marek, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, Fuat, Keith, Paul K., Khaltaev, Nikolai, Kleine Tebbe, Jorg, Klimek, Ludger, N'Goran, Bernard Koffi, Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Laune, Daniel, Le Thi Tuyet, Lan, Li, Jingmei, Lieberman, Phillipe, Lipworth, Brian J., Renaud, Louis, Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Majer, Ivan, Makela, Mika, Manning, Peter J., Masjedi, Mohamad R., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Mercier, Jacques, Merk, Hans, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Mösges, Ralph, Nadif, Rachel, Namazova Baranova, Leyla, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Niggemann, Bodo, Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Palmer, Stephen, Panzner, Petr, Papi, Alberto, Park, Hae-Sim, Pavord, Ian, Pawankar, Ruby, Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Pohl, Wolfgang, Popov, Todor A., Postma, Dirkje S., Potter, Paul, Poulsen, Lars K., Rabe, Klaus F., Raciborski, Filip, Pontal, Françoise Radier, Reitamo, Sakari, Repka Ramírez, Maria Susana, Robalo Cordeiro, Carlos, Roberts, Graham, Rodenas, Francisco, Rolland, Christine, Rodriguez, Miguel Roman, Romano, Antonino, Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Larry, Rottem, Menachem, Sánchez Borges, Mario, Sastre Dominguez, Joaquim, Schmid Grendelmeier, Peter, Serrano, Eli, Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Strandberg, Timo, Sunyer, Jordi, Thijs, C., Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Van Hage, Marianne, Vandenplas, Olivier, Vezzani, Giorgio, Vichyanond, Pakit, Viegi, Giovanni, Wagenmann, Martin, Wahn, Ulrich, De Yun, Wang, Williams, D. M., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, and Zidarn, Mihaela

Published
2016

235. Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

Author

Bousquet, Jean, Farrell, J., Crooks, George, Hellings, Peter W., Bel, Elisabeth H., Bewick, M., Chavannes, Niels H., Correia de Sousa, J., Cruz, A. A., Haahtela, Tari, Joos, Guy, Khaltaev, Nikolai, Malva, J., Muraro, Antonella, Nogues, M., Palkonen, Susanna, Pedersen, S., Robalo Cordeiro, Carlos, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Bedbrook, Anna, Aberer, Werner, Adachi, Mitsuru, Agusti, Alvar, Akdis, Cezmi, Akdis, Mubeccel, Ankri, J., Alonso, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arnavielhe, Sylvie, Arshad, S. Hasan, Bai, Chunxue, Baiardini, Ilaria, Bachert, Claus, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Kheder, A. Ben, Bennoor, Kazi S., Benson, Michael, Bergmann, Karl Christian, Bieber, T., Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Blasi, F., Boner, A. L., Bonini, Matteo, Bonini, Sergio, Bosnic Anticevitch, Sinthia, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Brozek, Jan L., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Canonica, G. Walter, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Carriazo, A., Casale, Thomas B., Cepeda Sarabia, A. M., Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Chung, K. F., Ciprandi, Georgio, Cirule, Ieva, Cox, Linda, Costa, D. J., Custovic, Adnan, Dahl, Ronald, Dahlen, Sven Erik, Darsow, Ulf, De Carlo, Giuseppe, De Blay, Frédéric, Dedeu, Tony, Deleanu, Diana, De Manuel Keenoy, Esteban, Demoly, Pascal, Denburg, J. A., Devillier, Phillipe, Didier, Alain, Dinh Xuan, Anh Tuan, Djukanovic, R., Dokic, D., Douagui, Habib B., Dray, Gérard, Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, R., Fabbri, L. Muller, Fletcher, Monica, Fiocchi, Alessandro, Fink Wagner, Antje H., Fonseca, Joao A., Fokkens, Wytske J., Forastiere, Francesco, Frith, P., Gaga, M., Gamkrelidze, Amiran, Garcés, J., García Aymerich, J., Gemicioğlu, Bilun, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Grisle, Ineta, Grouse, Lawrence, Gutter, Z., Guzmán, M. Antonieta, Heaney, L. G., Hellquist Dahl, Birthe, Henderson, D., Hendry, A., Heinrich, Joachim, Heve, D., Horak, F., Hourihane, J. O’. B., Howarth, P., Humbert, Marc, Hyland, M. E., Illario, M., Ivancevich, Juan Carlos, Jardim, José R., Jares, Edgardo José, Jeandel, C., Jenkins, C., Johnston, Sebastian L., Jonquet, Olivier, Julge, K., Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Klimek, Ludger, Koffi N'Goran, B., Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, M. L., Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Larenas Linnemann, Désirée, Laune, Daniel, Le, L. T. T., Lieberman, Phillipe, Lipworth, Brian J., Li, Jingmei, Lodrup Carlsen, Karin C., Louis, R., MacNee, W., Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Mair, A., Majer, Ivan, Makela, M. J., Manning, Peter J., Mara, S., Marshall, G. D., Masjedi, Mohamad R., Matignon, P., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Meltzer, E. O., Menzies Gow, A., Merk, Hans, Michel, J. P., Miculinic, N., Mihaltan, Florin, Milenkovic, Branislava, Mohammad, G. M. Y., Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Morgan, M., Mösges, Ralph, Mullol, Jaoquim, Nafti, S., Namazova Baranova, Leyla, Naclerio, Robert N., Neou, Angelos, Neffen, Hugo, Nekam, Kristof, Niggemann, Bodo, Ninot, G., Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Panzner, Petr, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae-Sim, Passalacqua, Giovanni, Pavord, Ian, Pawankar, Ruby, Pengelly, R., Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Poethig, D., Pohl, Wolfgang, Popov, Todor A., Portejoie, F., Potter, Paul, Postma, Dirkje S., Price, David, Rabe, Klaus F., Raciborski, Filip, Radier Pontal, F., Repka Ramirez, S., Reitamo, Sakari, Rennard, S., Rodenas, Francisco, Roberts, J., Roca, J., Rodriguez Mañas, L., Rolland, Christine, Roman Rodriguez, M., Romano, A., Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Lanny, Rottem, Menachem, Ryan, Dermot, Sánchez Borges, Mario, Scadding, Glenis K., Schünemann, Holger J., Serrano, Eli, Schmid Grendelmeier, Peter, Schulz, H., Sheikh, Aziz, Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Sterk, P. J., Sunyer, Jordi, Thijs, C., To, Teresa, Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Valia, E., Valovirta, Erkka, Van Ganse, E., Van Hage, Marianne, Vandenplas, Olivier, Vasankari, T., Vellas, B., Vestbo, J., Vezzani, G., Vichyanond, Pakit, Viegi, Giovanni, Vogelmeier, C., Vontetsianos, T., Wagenmann, Martin, Wallaert, B., Walker, Samantha, Wang, D. Y., Wahn, Ulrich, Wickman, Magnus, Williams, D. M., Williams, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zaidi, A., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, Mercier, Jacques, Bousquet, Jean, Farrell, J., Crooks, George, Hellings, Peter W., Bel, Elisabeth H., Bewick, M., Chavannes, Niels H., Correia de Sousa, J., Cruz, A. A., Haahtela, Tari, Joos, Guy, Khaltaev, Nikolai, Malva, J., Muraro, Antonella, Nogues, M., Palkonen, Susanna, Pedersen, S., Robalo Cordeiro, Carlos, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Bedbrook, Anna, Aberer, Werner, Adachi, Mitsuru, Agusti, Alvar, Akdis, Cezmi, Akdis, Mubeccel, Ankri, J., Alonso, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arnavielhe, Sylvie, Arshad, S. Hasan, Bai, Chunxue, Baiardini, Ilaria, Bachert, Claus, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Kheder, A. Ben, Bennoor, Kazi S., Benson, Michael, Bergmann, Karl Christian, Bieber, T., Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Blasi, F., Boner, A. L., Bonini, Matteo, Bonini, Sergio, Bosnic Anticevitch, Sinthia, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Brozek, Jan L., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Canonica, G. Walter, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Carriazo, A., Casale, Thomas B., Cepeda Sarabia, A. M., Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Chung, K. F., Ciprandi, Georgio, Cirule, Ieva, Cox, Linda, Costa, D. J., Custovic, Adnan, Dahl, Ronald, Dahlen, Sven Erik, Darsow, Ulf, De Carlo, Giuseppe, De Blay, Frédéric, Dedeu, Tony, Deleanu, Diana, De Manuel Keenoy, Esteban, Demoly, Pascal, Denburg, J. A., Devillier, Phillipe, Didier, Alain, Dinh Xuan, Anh Tuan, Djukanovic, R., Dokic, D., Douagui, Habib B., Dray, Gérard, Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, R., Fabbri, L. Muller, Fletcher, Monica, Fiocchi, Alessandro, Fink Wagner, Antje H., Fonseca, Joao A., Fokkens, Wytske J., Forastiere, Francesco, Frith, P., Gaga, M., Gamkrelidze, Amiran, Garcés, J., García Aymerich, J., Gemicioğlu, Bilun, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Grisle, Ineta, Grouse, Lawrence, Gutter, Z., Guzmán, M. Antonieta, Heaney, L. G., Hellquist Dahl, Birthe, Henderson, D., Hendry, A., Heinrich, Joachim, Heve, D., Horak, F., Hourihane, J. O’. B., Howarth, P., Humbert, Marc, Hyland, M. E., Illario, M., Ivancevich, Juan Carlos, Jardim, José R., Jares, Edgardo José, Jeandel, C., Jenkins, C., Johnston, Sebastian L., Jonquet, Olivier, Julge, K., Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Klimek, Ludger, Koffi N'Goran, B., Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, M. L., Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Larenas Linnemann, Désirée, Laune, Daniel, Le, L. T. T., Lieberman, Phillipe, Lipworth, Brian J., Li, Jingmei, Lodrup Carlsen, Karin C., Louis, R., MacNee, W., Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Mair, A., Majer, Ivan, Makela, M. J., Manning, Peter J., Mara, S., Marshall, G. D., Masjedi, Mohamad R., Matignon, P., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Meltzer, E. O., Menzies Gow, A., Merk, Hans, Michel, J. P., Miculinic, N., Mihaltan, Florin, Milenkovic, Branislava, Mohammad, G. M. Y., Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Morgan, M., Mösges, Ralph, Mullol, Jaoquim, Nafti, S., Namazova Baranova, Leyla, Naclerio, Robert N., Neou, Angelos, Neffen, Hugo, Nekam, Kristof, Niggemann, Bodo, Ninot, G., Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Panzner, Petr, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae-Sim, Passalacqua, Giovanni, Pavord, Ian, Pawankar, Ruby, Pengelly, R., Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Poethig, D., Pohl, Wolfgang, Popov, Todor A., Portejoie, F., Potter, Paul, Postma, Dirkje S., Price, David, Rabe, Klaus F., Raciborski, Filip, Radier Pontal, F., Repka Ramirez, S., Reitamo, Sakari, Rennard, S., Rodenas, Francisco, Roberts, J., Roca, J., Rodriguez Mañas, L., Rolland, Christine, Roman Rodriguez, M., Romano, A., Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Lanny, Rottem, Menachem, Ryan, Dermot, Sánchez Borges, Mario, Scadding, Glenis K., Schünemann, Holger J., Serrano, Eli, Schmid Grendelmeier, Peter, Schulz, H., Sheikh, Aziz, Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Sterk, P. J., Sunyer, Jordi, Thijs, C., To, Teresa, Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Valia, E., Valovirta, Erkka, Van Ganse, E., Van Hage, Marianne, Vandenplas, Olivier, Vasankari, T., Vellas, B., Vestbo, J., Vezzani, G., Vichyanond, Pakit, Viegi, Giovanni, Vogelmeier, C., Vontetsianos, T., Wagenmann, Martin, Wallaert, B., Walker, Samantha, Wang, D. Y., Wahn, Ulrich, Wickman, Magnus, Williams, D. M., Williams, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zaidi, A., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, and Mercier, Jacques

Published
2016

236. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Cardiometabolic Health, Circulatory Health, Child Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Public Health Epidemiologie, Other research (not in main researchprogram), Bousquet, Jean, Schünemann, Holger J, Hellings, Peter W, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl-Christian, Bosnic-Anticevich, Sinthia, Brozek, Jan, Calderon, Moises, Canonica, G Walter, Casale, Thomas B, Chavannes, Niels H, Cox, Linda, Chrystyn, Henry, Cruz, Alvaro A, Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J, Fonseca, Joao, Gonzalez-Diaz, Sandra N, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas-Linnemann, Désirée, Lodrup Carlsen, Karin C, Meltzer, Eli O, Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N, Palkonen, Susanna, Papadopoulos, Nikolaos G, Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K, Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, MASK study group*, Cardiometabolic Health, Circulatory Health, Child Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Public Health Epidemiologie, Other research (not in main researchprogram), Bousquet, Jean, Schünemann, Holger J, Hellings, Peter W, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bergmann, Karl-Christian, Bosnic-Anticevich, Sinthia, Brozek, Jan, Calderon, Moises, Canonica, G Walter, Casale, Thomas B, Chavannes, Niels H, Cox, Linda, Chrystyn, Henry, Cruz, Alvaro A, Dahl, Ronald, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Phillipe, Dray, Gérard, Fletcher, Monica, Fokkens, Wytske J, Fonseca, Joao, Gonzalez-Diaz, Sandra N, Grouse, Lawrence, Keil, Thomas, Kuna, Piotr, Larenas-Linnemann, Désirée, Lodrup Carlsen, Karin C, Meltzer, Eli O, Mullol, Jaoquim, Muraro, Antonella, Naclerio, Robert N, Palkonen, Susanna, Papadopoulos, Nikolaos G, Passalacqua, Giovanni, Price, David, Ryan, Dermot, Samolinski, Boleslaw, Scadding, Glenis K, Sheikh, Aziz, Spertini, François, Valiulis, Arunas, Valovirta, Erkka, Walker, Samantha, Wickman, Magnus, Yorgancioglu, Arzu, Haahtela, Tari, and MASK study group*

Published
2016

237. Precision medicine in patients with allergic diseases:Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

Author

Muraro, Antonella, Lemanske, Robert F, Hellings, Peter W, Akdis, Cezmi A, Bieber, Thomas, Casale, Thomas B, Jutel, Marek, Ong, Peck Y, Poulsen, Lars K, Schmid-Grendelmeier, Peter, Simon, Hans-Uwe, Seys, Sven F, Agache, Ioana, Muraro, Antonella, Lemanske, Robert F, Hellings, Peter W, Akdis, Cezmi A, Bieber, Thomas, Casale, Thomas B, Jutel, Marek, Ong, Peck Y, Poulsen, Lars K, Schmid-Grendelmeier, Peter, Simon, Hans-Uwe, Seys, Sven F, and Agache, Ioana

Abstract

In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration platform. PRACTALL is an initiative of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology aiming to harmonize the European and American approaches to best allergy practice and science. Precision medicine is of broad relevance for the management of asthma, rhinitis, and atopic dermatitis in the context of a better selection of treatment responders, risk prediction, and design of disease-modifying strategies. Progress has been made in profiling the type 2 immune response-driven asthma. The endotype driven approach for non-type 2 immune response asthma, rhinitis, and atopic dermatitis is lagging behind. Validation and qualification of biomarkers are needed to facilitate their translation into pathway-specific diagnostic tests. Wide consensus between academia, governmental regulators, and industry for further development and application of precision medicine in management of allergic diseases is of utmost importance. Improved knowledge of disease pathogenesis together with defining validated and qualified biomarkers are key approaches to precision medicine.

Published
2016

238. Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

Author

Bousquet, Jean J., Farrell, J., Crooks, George, Hellings, Peter W., Bel, Elisabeth H., Bewick, M., Chavannes, Niels H., Correia de Sousa, Jaime, Cruz, A. A., Haahtela, Tari, Joos, Guy, Khaltaev, Nikolai, Malva, J., Muraro, Antonella, Nogues, M., Palkonen, Susanna, Pedersen, S., Robalo Cordeiro, Carlos, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Bedbrook, Anna, Aberer, Werner, Adachi, Mitsuru, Agusti, Alvar, Akdis, Cezmi, Akdis, Mubeccel, Ankri, J., Alonso, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arnavielhe, Sylvie, Arshad, S. Hasan, Bai, Chunxue, Baiardini, Ilaria, Bachert, Claus, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Kheder, A. Ben, Bennoor, Kazi S., Benson, Michael, Bergmann, Karl Christian, Bieber, T., Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Blasi, F., Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic Anticevitch, Sinthia, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Brozek, Jan L., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Canonica, Giorgio Walter, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Carriazo, A., Casale, Thomas B., Cepeda Sarabia, A. M., Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Chung, K. F., Ciprandi, Georgio, Cirule, Ieva, Cox, Linda, Costa, David J., Custovic, Adnan, Dahl, Ronald, Dahlen, Sven Erik, Darsow, Ulf, De Carlo, Giuseppe, De Blay, Frédéric, Dedeu, Tony, Deleanu, Diana, De Manuel Keenoy, Esteban, Demoly, Pascal, Denburg, J. A., Devillier, Phillipe, Didier, Alain, Dinh Xuan, Anh Tuan, Djukanovic, R., Dokic, Dejan, Douagui, Habib B., Dray, Gérard, Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, R., Fabbri, L. Muller, Fletcher, Monica, Fiocchi, Alessandro, Fink Wagner, Antje H., Fonseca, Joao A., Fokkens, Wytske J., Forastiere, Francesco, Frith, P., Gaga, M., Gamkrelidze, Amiran, Garcés, J., García Aymerich, J., Gemicioğlu, Bilun, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Grisle, Ineta, Grouse, Lawrence, Gutter, Z., Guzmán Meléndez, María Antonieta, Heaney, L. G., Hellquist Dahl, Birthe, Henderson, D., Hendry, A., Heinrich, Joachim, Heve, D., Horak, Friedrich, Hourihane, J. O’. B., Howarth, Peter H., Humbert, Marc, Hyland, Michael E., Illario, M., Ivancevich, Juan Carlos, Jardim, José R., Jares, Edgardo José, Jeandel, C., Jenkins, C., Johnston, Sebastian L., Jonquet, Olivier, Julge, K., Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Klimek, Ludger, Koffi N'Goran, B., Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Larenas Linnemann, Désirée, Laune, Daniel, Le, L. T. T., Lieberman, Phillipe, Lipworth, Brian J., Li, Jingmei, Lodrup Carlsen, Karin C., Louis, R., MacNee, W., Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Mair, A., Majer, Ivan, Makela, M. J., Manning, Peter J., Mara, S., Marshall, G. D., Masjedi, Mohamad R., Matignon, P., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Meltzer, E. O., Menzies Gow, A., Merk, Hans, Michel, J. P., Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, G. M. Y., Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Morgan, M., Mösges, Ralph, Mullol, Jaoquim, Nafti, S., Namazova Baranova, Leyla, Naclerio, Robert N., Neou, Angelos, Neffen, Hugo, Nekam, Kristof, Niggemann, Bodo, Ninot, G., Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Panzner, Petr, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae-Sim, Passalacqua, Giovanni, Pavord, Ian, Pawankar, Ruby, Pengelly, R., Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Poethig, D., Pohl, Wolfgang, Popov, Todor A., Portejoie, F., Potter, Paul, Postma, Dirkje S., Price, David, Rabe, Klaus F., Raciborski, Filip, Radier Pontal, F., Repka Ramírez, Maria Susana, Reitamo, Sakari, Rennard, S., Rodenas, Francisco, Roberts, J., Roca, J., Rodriguez Mañas, L., Rolland, Christine, Roman Rodriguez, M., Romano, A., Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Lanny, Rottem, Menachem, Ryan, Dermot, Sánchez Borges, Mario, Scadding, Glenis K., Schünemann, Holger J., Serrano, Eli, Schmid Grendelmeier, Peter, Schulz, H., Sheikh, Aziz, Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Sterk, P. J., Sunyer, Jordi, Thijs, C., To, Teresa, Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Valia, E., Valovirta, Erkka, Van Ganse, E., Van Hage, Marianne, Vandenplas, Olivier, Vasankari, T., Vellas, B., Vestbo, J., Vezzani, Giorgio, Vichyanond, Pakit, Viegi, Giovanni, Vogelmeier, C., Vontetsianos, T., Wagenmann, Martin, Wallaert, B., Walker, Samantha, Wang, D. Y., Wahn, Ulrich, Wickman, Magnus, Williams, D. M., Williams, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zaidi, A., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, Mercier, Jacques, Bousquet, Jean J., Farrell, J., Crooks, George, Hellings, Peter W., Bel, Elisabeth H., Bewick, M., Chavannes, Niels H., Correia de Sousa, Jaime, Cruz, A. A., Haahtela, Tari, Joos, Guy, Khaltaev, Nikolai, Malva, J., Muraro, Antonella, Nogues, M., Palkonen, Susanna, Pedersen, S., Robalo Cordeiro, Carlos, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Bedbrook, Anna, Aberer, Werner, Adachi, Mitsuru, Agusti, Alvar, Akdis, Cezmi, Akdis, Mubeccel, Ankri, J., Alonso, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep M., Arnavielhe, Sylvie, Arshad, S. Hasan, Bai, Chunxue, Baiardini, Ilaria, Bachert, Claus, Baigenzhin, Abay K., Barbara, Cristina, Bateman, Eric D., Beghé, Bianca, Kheder, A. Ben, Bennoor, Kazi S., Benson, Michael, Bergmann, Karl Christian, Bieber, T., Bindslev Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Blasi, F., Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic Anticevitch, Sinthia, Boulet, Louis Philippe, Bourret, Rodolphe A., Bousquet, Philippe J., Braido, Fulvio, Briggs, Andrew H., Brightling, Christopher E., Brozek, Jan L., Buhl, Roland, Burney, Peter G., Bush, Andrew, Caballero Fonseca, Fernando, Caimmi, Davide P., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Canonica, Giorgio Walter, Camuzat, Thierry, Carlsen, Kai Hakon, Carr, Warner, Carriazo, A., Casale, Thomas B., Cepeda Sarabia, A. M., Chatzi, Leda, Chen, Yuzhi Z., Chiron, Raphaël, Chkhartishvili, Ekaterine, Chuchalin, Alexander G., Chung, K. F., Ciprandi, Georgio, Cirule, Ieva, Cox, Linda, Costa, David J., Custovic, Adnan, Dahl, Ronald, Dahlen, Sven Erik, Darsow, Ulf, De Carlo, Giuseppe, De Blay, Frédéric, Dedeu, Tony, Deleanu, Diana, De Manuel Keenoy, Esteban, Demoly, Pascal, Denburg, J. A., Devillier, Phillipe, Didier, Alain, Dinh Xuan, Anh Tuan, Djukanovic, R., Dokic, Dejan, Douagui, Habib B., Dray, Gérard, Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, Emuzyte, R., Fabbri, L. Muller, Fletcher, Monica, Fiocchi, Alessandro, Fink Wagner, Antje H., Fonseca, Joao A., Fokkens, Wytske J., Forastiere, Francesco, Frith, P., Gaga, M., Gamkrelidze, Amiran, Garcés, J., García Aymerich, J., Gemicioğlu, Bilun, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Grisle, Ineta, Grouse, Lawrence, Gutter, Z., Guzmán Meléndez, María Antonieta, Heaney, L. G., Hellquist Dahl, Birthe, Henderson, D., Hendry, A., Heinrich, Joachim, Heve, D., Horak, Friedrich, Hourihane, J. O’. B., Howarth, Peter H., Humbert, Marc, Hyland, Michael E., Illario, M., Ivancevich, Juan Carlos, Jardim, José R., Jares, Edgardo José, Jeandel, C., Jenkins, C., Johnston, Sebastian L., Jonquet, Olivier, Julge, K., Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor P., Khaitov, Musa R., Kalayci, Omer, Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Klimek, Ludger, Koffi N'Goran, B., Kolek, Vítězslav, Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Lambrecht, Bart, Lau, Susanne, Larenas Linnemann, Désirée, Laune, Daniel, Le, L. T. T., Lieberman, Phillipe, Lipworth, Brian J., Li, Jingmei, Lodrup Carlsen, Karin C., Louis, R., MacNee, W., Magard, Yves, Magnan, Antoine, Mahboub, Bassam, Mair, A., Majer, Ivan, Makela, M. J., Manning, Peter J., Mara, S., Marshall, G. D., Masjedi, Mohamad R., Matignon, P., Maurer, Marcus, Mavale Manuel, Sandra, Melén, Erik, Melo Gomes, Elisabete, Meltzer, E. O., Menzies Gow, A., Merk, Hans, Michel, J. P., Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, G. M. Y., Molimard, Mathieu, Momas, Isabelle, Montilla Santana, Anna, Morais Almeida, Mario, Morgan, M., Mösges, Ralph, Mullol, Jaoquim, Nafti, S., Namazova Baranova, Leyla, Naclerio, Robert N., Neou, Angelos, Neffen, Hugo, Nekam, Kristof, Niggemann, Bodo, Ninot, G., Nyembue, T. Dieudonné, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kim, Ouedraogo, Solange, Paggiaro, Pier Luigi, Pali Schöll, Isabella, Panzner, Petr, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae-Sim, Passalacqua, Giovanni, Pavord, Ian, Pawankar, Ruby, Pengelly, R., Pfaar, Oliver, Picard, Robert, Pigearias, Bernard, Pin, Isabelle, Plavec, Davor, Poethig, D., Pohl, Wolfgang, Popov, Todor A., Portejoie, F., Potter, Paul, Postma, Dirkje S., Price, David, Rabe, Klaus F., Raciborski, Filip, Radier Pontal, F., Repka Ramírez, Maria Susana, Reitamo, Sakari, Rennard, S., Rodenas, Francisco, Roberts, J., Roca, J., Rodriguez Mañas, L., Rolland, Christine, Roman Rodriguez, M., Romano, A., Rosado Pinto, José, Rosario, Nelson A., Rosenwasser, Lanny, Rottem, Menachem, Ryan, Dermot, Sánchez Borges, Mario, Scadding, Glenis K., Schünemann, Holger J., Serrano, Eli, Schmid Grendelmeier, Peter, Schulz, H., Sheikh, Aziz, Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Simons, F. Estelle R., Sisul Alvariza, Juan Carlos, Skrindo, Ingebjorg, Smit, Henriette A., Solé, Dirceu, Sooronbaev, Talant, Spranger, Otto, Stelmach, Raphael, Sterk, P. J., Sunyer, Jordi, Thijs, C., To, Teresa, Todo Bom, Ana Maria, Triggiani, Massimo, Valenta, Rudolf, Valero, Antonio L., Valia, E., Valovirta, Erkka, Van Ganse, E., Van Hage, Marianne, Vandenplas, Olivier, Vasankari, T., Vellas, B., Vestbo, J., Vezzani, Giorgio, Vichyanond, Pakit, Viegi, Giovanni, Vogelmeier, C., Vontetsianos, T., Wagenmann, Martin, Wallaert, B., Walker, Samantha, Wang, D. Y., Wahn, Ulrich, Wickman, Magnus, Williams, D. M., Williams, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Yusuf, Osman M., Zaidi, A., Zar, Heather J., Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, and Mercier, Jacques

Published
2016

239. Impaired barrier function in patients with house dust mite–induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression

Author

Steelant, Brecht, Farré, Ricard, Wawrzyniak, Paulina, Belmans, Jochen, Dekimpe, Emily, Vanheel, Hanne, Van Gerven, Laura, Kortekaas Krohn, Inge, Bullens, Dominique M A, Ceuppens, Jan L, Akdis, Cezmi A, Boeckxstaens, Guy, Seys, Sven F, Hellings, Peter W, Steelant, Brecht, Farré, Ricard, Wawrzyniak, Paulina, Belmans, Jochen, Dekimpe, Emily, Vanheel, Hanne, Van Gerven, Laura, Kortekaas Krohn, Inge, Bullens, Dominique M A, Ceuppens, Jan L, Akdis, Cezmi A, Boeckxstaens, Guy, Seys, Sven F, and Hellings, Peter W

Published
2016

240. Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

Author

Muraro, Antonella, Lemanske, Robert F, Hellings, Peter W, Akdis, Cezmi A, Bieber, Thomas, Casale, Thomas B, Jutel, Marek, Ong, Peck Y, Poulsen, Lars K, Schmid-Grendelmeier, Peter, Simon, Hans-Uwe, Seys, Sven F, Agache, Ioana, Muraro, Antonella, Lemanske, Robert F, Hellings, Peter W, Akdis, Cezmi A, Bieber, Thomas, Casale, Thomas B, Jutel, Marek, Ong, Peck Y, Poulsen, Lars K, Schmid-Grendelmeier, Peter, Simon, Hans-Uwe, Seys, Sven F, and Agache, Ioana

Published
2016

241. List of Contributors

Author

Agache, Ioana, Akdis, Cezmi A., Alvarez-Perea, Alberto, Amaral, Rita, Antolín-Amérigo, Darío, Bachert, Claus, Baiardini, Ilaria, Berkouk, Karim, Bewick, Mike, Bousquet, Jean, Canonica, Giorgio Walter, Cojanu, Catalina, Crisafulli, Aldo, Desrosiers, Martin, Dörr, Tamara, Endam, Leandra Mfuna, Ferrando, Matteo, Fokkens, Wytske, Fonseca, João A, Gajdanowicz, Paweł, Haahtela, Tari, Hanrahan, Finnian, Heffler, Enrico, Hellings, Peter W., Hofmaier, Stephanie, Hofman, Ingrid van, Hogan, Stéphane, Hopkins, Claire, Huang, Xinyuan, Jacinto, Tiago, Jácome, Cristina, Jones, Christina, Jutel, Marek, Kogan, Grigorij, Laang, Hannu, Lund, Valerie J., Lunjani, Nonhlanhla, Mäkelä, Mika J., Mariën, Gert, Matricardi, Paolo Maria, Matthiessen, Line, Nowak, Elisabeth, O’Mahony, Liam, Paoletti, Giovanni, Pereira, Ana Margarida, Popescu, Florin-Dan, Pugin, Benoit, Rogozea, Liliana, Ryan, Dermot, Saarinen, Kimmo, Schaub, Bianca, Schmidt-Weber, Carsten B., Sedillot, Eve, Seys, Sven F., Smith, Helen E., Sokolowska, Milena, Steelant, Brecht, Sugita, Kazunari, Tomassen, Peter, Tommila, Erja, Trzaska, Dominika, Valovirta, Erkka, Vasankari, Tuula, Vidal-Ragout, María, Wong, Gary W.K., Yorgancıoğlu, Arzu, and Zuberbier, Torsten

Published
2019
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243. Improvement of nasal breathing and patient satisfaction by the endonasal dilator Airmax®

Author

Hellings, Peter W., Nolst Trenite, G. J., Ear, Nose and Throat, and Other departments

Subjects
otorhinolaryngologic diseases, respiratory system
Abstract

Patients suffering from nasal obstruction due to external nasal valve dysfunction may benefit from either corrective surgery or a conservative approach with a nasal dilator. At present, devices for widening the external nasal valve region can be applied externally or endonasally. It remains unknown to what extent the en dona sal dilator Airmax® objectively improves the nasal flow and can be offered as an alternative for surgery. Thirty patients suffering from nasal obstruction due to external nasal valve problems were proposed to use the nasal dilator for 4 weeks as an alternative for corrective surgery. The improvement of nasal flow by the dilator was evaluated by measuring the peak nasal inspiratory flow (PNIF). Then, patients were asked for their willingness to continue to use the nasal dilator or to undergo nasal valve surgery. The endonasal dilator improved the mean PNIF from baseline values with a mean increase of 176.1 o/o. After a 4 week trial period, 19 of 30 patients expressed the intention to continue the use of the nasal dilator. Inappropriate size, local irritation and/or aesthetic nasal complaints were mentioned by the other patients as reasons for discontinuation of using the nasal dilator. The endonasal dilator Airmax® represents a powerful device to improve nasal breathing in the target patients and therefore represents a good alternative for corrective surgery

Published
2014

244. SCUAD and chronic rhinosinusitis. Reinforcing hypothesis driven research in difficult cases

Author

Prokopakis, Emmanuel P. Vlastos, Ioannis M. Ferguson, Berrylin J. Scadding, Glenis Kawauchi, Hideyuki Georgalas, Christos and Papadopoulos, Nikolaos Hellings, Peter W.

Abstract

Background: Our objective is to present recent research findings on recalcitrant chronic rhinosinusitis (CRS) in relation to “Severe Chronic Upper Airway Disease” (SCUAD). Methodology: Literature review using Medline and Embase databases (search ternns’chronic rhinosinusitis”,”chronic sinusitis”or “Severe Chronic Upper Airway Disease”) limited to articles published in the English language. Results: Complex pathophysiological mechanisms characterize various forms of chronic rhinitis and rhinosinusitis (CRS), where inflammation persists in spite of adequate medical treatment. In these cases, a multifactorial etiology often underlies the development of sino-nasal inflammation. The interaction between chronic upper and lower airway inflammation via neurogenic and systemic pathways may complicate the therapy of these patients, and lead to insufficient symptom control. Conclusion: The recently introduced definition of”Severe Chronic Upper Airway Disease” (SCUAD) increases awareness of those patients with persistent inflammation and symptoms despite guideline-driven pharmacologic treatment. The concept of SCUAD may prove helpful in directing research towards clarifying the definition, diagnosis and pathophysiology of rhinitis and rhinosinusitis, their limits and overlap. In this review, a hypothesis on SCUAD immunopathology is also presented.

Published
2014

246. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, Jean, primary, Schünemann, Holger J., additional, Hellings, Peter W., additional, Arnavielhe, Sylvie, additional, Bachert, Claus, additional, Bedbrook, Anna, additional, Bergmann, Karl-Christian, additional, Bosnic-Anticevich, Sinthia, additional, Brozek, Jan, additional, Calderon, Moises, additional, Canonica, G. Walter, additional, Casale, Thomas B., additional, Chavannes, Niels H., additional, Cox, Linda, additional, Chrystyn, Henry, additional, Cruz, Alvaro A., additional, Dahl, Ronald, additional, De Carlo, Giuseppe, additional, Demoly, Pascal, additional, Devillier, Phillipe, additional, Dray, Gérard, additional, Fletcher, Monica, additional, Fokkens, Wytske J., additional, Fonseca, Joao, additional, Gonzalez-Diaz, Sandra N., additional, Grouse, Lawrence, additional, Keil, Thomas, additional, Kuna, Piotr, additional, Larenas-Linnemann, Désirée, additional, Lodrup Carlsen, Karin C., additional, Meltzer, Eli O., additional, Mullol, Jaoquim, additional, Muraro, Antonella, additional, Naclerio, Robert N., additional, Palkonen, Susanna, additional, Papadopoulos, Nikolaos G., additional, Passalacqua, Giovanni, additional, Price, David, additional, Ryan, Dermot, additional, Samolinski, Boleslaw, additional, Scadding, Glenis K., additional, Sheikh, Aziz, additional, Spertini, François, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Walker, Samantha, additional, Wickman, Magnus, additional, Yorgancioglu, Arzu, additional, Haahtela, Tari, additional, Zuberbier, Torsten, additional, Aberer, Werner, additional, Adachi, Mitsuru, additional, Agache, Ioana, additional, Akdis, Cezmi, additional, Akdis, Mubeccel, additional, Annesi-Maesano, Isabella, additional, Ansotegui, Ignacio J., additional, Anto, Josep M., additional, Arshad, S. Hasan, additional, Baiardini, Ilaria, additional, Baigenzhin, Abay K., additional, Barbara, Cristina, additional, Bateman, Eric D., additional, Beghé, Bianca, additional, Bel, Elisabeth H., additional, Ben Kheder, Ali, additional, Bennoor, Kazi S., additional, Benson, Michael, additional, Bernstein, David, additional, Michael, Bewick, additional, Thomas, Bieber, additional, Bindslev-Jensen, Carsten, additional, Bjermer, Leif, additional, Blain, Hubert, additional, Boner, Attilio, additional, Bonini, Matteo, additional, Bonini, Sergio, additional, Bosse, Isabelle, additional, Bouchard, Jacques, additional, Boulet, Louis-Philippe, additional, Bourret, Rodolphe A., additional, Bousquet, Philippe J., additional, Braido, Fulvio, additional, Briggs, Andrew H., additional, Brightling, Christopher E., additional, Buhl, Roland, additional, Burney, Peter, additional, Bush, Andrew, additional, Caballero-Fonseca, Fernando, additional, Caimmi, Davide P., additional, Camargos, Paulo, additional, Camuzat, Thierry, additional, Carlsen, Kai-Hakon, additional, Carr, Warner, additional, Sarabia, Alfonso Cepeda, additional, Chatzi, Leda, additional, Chen, Yuzhi, additional, Chiron, Raphaël, additional, Chkhartishvili, Ekaterine, additional, Chuchalin, Alexander, additional, Ciprandi, Georgio, additional, Cirule, Ieva, additional, Correia de Sousa, Jaime, additional, Costa, David, additional, Crooks, George, additional, Custovic, Adnan, additional, Dahlen, Sven-Erik, additional, Darsow, Ulf, additional, De Blay, Frédéric, additional, De Manuel Keenoy, Esteban, additional, Dedeu, Tony, additional, Deleanu, Diana, additional, Denburg, Judah, additional, Didier, Alain, additional, Dinh-Xuan, Anh-Tuan, additional, Dokic, Dejan, additional, Douagui, Habib B., additional, Dubakiene, Ruta, additional, Durham, Stephen, additional, Dykewicz, Mark, additional, El-Gamal, Yehia, additional, Emuzyte, Regina, additional, Fink-Wagner, Antje, additional, Fiocchi, Alessandro, additional, Forastiere, Francesco, additional, Gamkrelidze, Amiran, additional, Gemicioğlu, Bilun, additional, Gereda, Jose E., additional, Gerth van Wijk, Roy, additional, Gotua, Maia, additional, Grisle, Ineta, additional, Guzmán, M. Antonieta, additional, Heinrich, Joachim, additional, Hellquist-Dahl, Birthe, additional, Horak, Friedrich, additional, Howarth, Peter H., additional, Humbert, Marc, additional, Hyland, Michael, additional, Ivancevich, Juan-Carlos, additional, Jares, Edgardo J., additional, Johnston, Sebastian L., additional, Jonquet, Olivier, additional, Joos, Guy, additional, Jung, Ki-Suck, additional, Just, Jocelyne, additional, Jutel, Marek, additional, Kaidashev, Igor P., additional, Khaitov, Musa, additional, Kalayci, Omer, additional, Kalyoncu, Fuat, additional, Keith, Paul, additional, Khaltaev, Nikolai, additional, Kleine-Tebbe, Jorg, additional, Klimek, Ludger, additional, N'Goran, Bernard Koffi, additional, Kolek, Vitezlav, additional, Koppelman, Gerard H., additional, Kowalski, Marek, additional, Kull, Inger, additional, Kvedariene, Violeta, additional, Lambrecht, Bart, additional, Lau, Susanne, additional, Laune, Daniel, additional, Le Thi Tuyet, Lan, additional, Li, Jing, additional, Lieberman, Phillipe, additional, Lipworth, Brian J., additional, Renaud, Louis, additional, Magard, Yves, additional, Magnan, Antoine, additional, Mahboub, Bassam, additional, Majer, Ivan, additional, Makela, Mika, additional, Manning, Peter J., additional, Masjedi, Mohamad R., additional, Maurer, Marcus, additional, Mavale-Manuel, Sandra, additional, Melén, Erik, additional, Melo-Gomes, Elisabete, additional, Mercier, Jacques, additional, Merk, Hans, additional, Miculinic, Neven, additional, Mihaltan, Florin, additional, Milenkovic, Branislava, additional, Mohammad, Yousser, additional, Molimard, Mathieu, additional, Momas, Isabelle, additional, Montilla-Santana, Anna, additional, Morais-Almeida, Mario, additional, Mösges, Ralph, additional, Nadif, Rachel, additional, Namazova-Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristof, additional, Neou, Angelos, additional, Niggemann, Bodo, additional, Nyembue, Dieudonné, additional, O'Hehir, Robyn, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Okubo, Kim, additional, Ouedraogo, Solange, additional, Paggiaro, Pier-Luigi, additional, Pali-Schöll, Isabella, additional, Palmer, Stephen, additional, Panzner, Petr, additional, Papi, Alberto, additional, Park, Hae-Sim, additional, Pavord, Ian, additional, Pawankar, Ruby, additional, Pfaar, Oliver, additional, Picard, Robert, additional, Pigearias, Bernard, additional, Pin, Isabelle, additional, Plavec, Davor, additional, Pohl, Wolfgang, additional, Popov, Todor, additional, Postma, Dirkje S., additional, Potter, Paul, additional, Poulsen, Lars K., additional, Rabe, Klaus F., additional, Raciborski, Filip, additional, Pontal, Françoise Radier, additional, Reitamo, Sakari, additional, Repka-Ramirez, Maria-Susana, additional, Robalo-Cordeiro, Carlos, additional, Roberts, Graham, additional, Rodenas, Francisco, additional, Rolland, Christine, additional, Rodriguez, Miguel Roman, additional, Romano, Antonino, additional, Rosado-Pinto, José, additional, Rosario, Nelson A., additional, Rosenwasser, Larry, additional, Rottem, Menachem, additional, Sanchez-Borges, Mario, additional, Sastre-Dominguez, Joaquim, additional, Schmid-Grendelmeier, Peter, additional, Serrano, Eli, additional, Simons, F. Estelle R., additional, Sisul, Juan-Carlos, additional, Skrindo, Ingebjorg, additional, Smit, Henriette A., additional, Solé, Dirceu, additional, Sooronbaev, Talant, additional, Spranger, Otto, additional, Stelmach, Rafael, additional, Strandberg, Timo, additional, Sunyer, Jordi, additional, Thijs, Carel, additional, Todo-Bom, Ana-Maria, additional, Triggiani, Massimo, additional, Valenta, Rudolf, additional, Valero, Antonio L., additional, van Hage, Marianne, additional, Vandenplas, Olivier, additional, Vezzani, Giorgio, additional, Vichyanond, Pakit, additional, Viegi, Giovanni, additional, Wagenmann, Martin, additional, Wahn, Ulrich, additional, De Yun, Wang, additional, Williams, Denis, additional, Wright, John, additional, Yawn, Barbara P., additional, Yiallouros, Panayiotis, additional, Yusuf, Osman M., additional, Zar, Heather J., additional, Zernotti, Mario, additional, Zhang, Luo, additional, Zhong, Nanshan, additional, and Zidarn, Mihaela, additional

Published
2016
Full Text
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248. Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

Author

Muraro, Antonella, primary, Lemanske, Robert F., additional, Hellings, Peter W., additional, Akdis, Cezmi A., additional, Bieber, Thomas, additional, Casale, Thomas B., additional, Jutel, Marek, additional, Ong, Peck Y., additional, Poulsen, Lars K., additional, Schmid-Grendelmeier, Peter, additional, Simon, Hans-Uwe, additional, Seys, Sven F., additional, and Agache, Ioana, additional

Published
2016
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249. Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

Author

Wouters, Mira M., primary, Balemans, Dafne, additional, Van Wanrooy, Sander, additional, Dooley, James, additional, Cibert-Goton, Vincent, additional, Alpizar, Yeranddy A., additional, Valdez-Morales, Eduardo E., additional, Nasser, Yasmin, additional, Van Veldhoven, Paul P., additional, Vanbrabant, Winde, additional, Van der Merwe, Schalk, additional, Mols, Raf, additional, Ghesquière, Bart, additional, Cirillo, Carla, additional, Kortekaas, Inge, additional, Carmeliet, Peter, additional, Peetermans, Willy E., additional, Vermeire, Séverine, additional, Rutgeerts, Paul, additional, Augustijns, Patrick, additional, Hellings, Peter W., additional, Belmans, Ann, additional, Vanner, Stephen, additional, Bulmer, David C., additional, Talavera, Karel, additional, Vanden Berghe, Pieter, additional, Liston, Adrian, additional, and Boeckxstaens, Guy E., additional

Published
2016
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250. Impaired barrier function in patients with house dust mite–induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression

Author

Steelant, Brecht, primary, Farré, Ricard, additional, Wawrzyniak, Paulina, additional, Belmans, Jochen, additional, Dekimpe, Emily, additional, Vanheel, Hanne, additional, Van Gerven, Laura, additional, Kortekaas Krohn, Inge, additional, Bullens, Dominique M.A., additional, Ceuppens, Jan L., additional, Akdis, Cezmi A., additional, Boeckxstaens, Guy, additional, Seys, Sven F., additional, and Hellings, Peter W., additional

Published
2016
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