758 results on '"Grimes, H. Leighton"'
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202. The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity
203. Contributions to Neutropenia from PFAAP5 (N4BP2L2), a Novel Protein Mediating Transcriptional Repressor Cooperation between Gfi1 and Neutrophil Elastase
204. The 3′ End of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to the 5′ Insulator Core and Is Necessary in Conjunction with the Core for Full Insulator Activity
205. The Ski oncoprotein regulates Hematopoietic Stem Cell Fitness and Functions as a Corepressor for Gfi1.
206. GFI1 Is a Tumor Suppressor in Myeloid Progenitors
207. Ajuba Functions as An HDAC-Dependent Co-Repressor for Autoregulation of the Growth Factor Independent-1 Transcription Factor
208. Gfi1 as a Regulator of Hematopoietic Differentiation.
209. Deregulation of MicroRNA Underlies Severe Congenital Neutropenia Pathogenesis
210. Ajuba Functions as a Histone Deacetylase-dependent Co-repressor for Autoregulation of the Growth Factor-independent-1 Transcription Factor
211. Hox and Senseless Antagonism Functions as a Molecular Switch to Regulate EGF Secretion in the Drosophila PNS
212. Mutations in Growth Factor Independent-1 Associated with Human Neutropenia Block Murine Granulopoiesis through Colony Stimulating Factor-1
213. A Conserved Mechanism of Transcription Factor Competition Controls Hematopoietic Progenitor Self-Renewal.
214. microRNA Control of Hematopoietic Stem Cell Fitness and Myelopoiesis.
215. The Human Severe Congenital Neutropenia-Associated Gfi1N382S Mutant Critically Requires Deregulated Expression of CSF1 To Block Granulopoiesis.
216. Epigenetic Regulation of Protein-Coding and MicroRNA Genes by the Gfi1-Interacting Tumor Suppressor PRDM5
217. Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
218. Loss of GFI1 impairs pulmonary neuroendorine cell proliferation, but the neuroendocrine phenotype has limited impact on post-naphthalene airway repair
219. Gfi1-N382S Mutants from Human Severe Congenital Neutropenia Patients Function through a Transcriptional Dominant Negative Mechanism.
220. A Gene Dosage Requirement for Transcription Factor Gfi1 in the Regulation of Myelopoiesis and Myeloproliferative Disorders.
221. miR-21 Is a Transcriptional Target of Growth Factor Independent -1; Implications for Transcriptional Regulation of microRNA.
222. T Cell Lymphopenia in Rhoh−/− Mice Results from Combined Defects of T Cell Migration and IL-7-Regulated Naïve T Cell Homeostasis.
223. The growth factor independence-1 transcription factor: New functions and new insights
224. Gfi1 Coordinates Epigenetic Repression of p21Cip/WAF1by Recruitment of Histone Lysine Methyltransferase G9a and Histone Deacetylase 1
225. Murine Modeling of Human Severe Congenital Neutropenia and Non-Immune Chronic Idopathic Neutropenia.
226. Growth Factor Independence-1 Is Expressed in Primary Human Neuroendocrine Lung Carcinomas and Mediates the Differentiation of Murine Pulmonary Neuroendocrine Cells
227. Graft facilitating cells are derived from hematopoietic stem cells and functionally require CD3, but are distinct from T lymphocytes
228. Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism
229. Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2
230. Growth Factor Independence-1B Expression Leads to Defects in T Cell Activation, IL-7 Receptor α Expression, and T Cell Lineage Commitment
231. The zinc finger transcription factorGfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival
232. Identification and Isolation of Hematopoietic Stem Cells and Progenitors with Discrete Developmental Gene Expression Programs
233. Graft tolerance and acceptance in xenotransplantation
234. A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes
235. pyInfinityFlow: optimized imputation and analysis of high-dimensional flow cytometry data for millions of cells.
236. Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
237. The Gfi-1B Proto-Oncoprotein Represses p21WAF1 and Inhibits Myeloid Cell Differentiation
238. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
239. The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death
240. MicroRNAs in the midst of myeloid signal transduction.
241. Distinct Roles of Cdc42 in Thymopoiesis and Effector and Memory T Cell Differentiation.
242. Gfi1 Coordinates Epigenetic Repression of p21Cip/WAF1 by Recruitment of Histone Lysine Methyltransferase G9a and Histone Deacetylase 1.
243. Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network
244. ATF3 is a novel regulator of mouse neutrophil migration
245. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms
246. Editorial introductions
247. Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress
248. The human GFI136N variant induces epigenetic changes at the Hoxa9locus and accelerates K-RAS driven myeloproliferative disorder in mice
249. Krüppel-Like Factor 5 Is Not Required for K-RasG12DLung Tumorigenesis, but Represses ABCG2 Expression and Is Associated with Better Disease-Specific Survival
250. Divisional Memory Drives Hematopoietic Stem Cell Functional Diversity
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