Search

Made available in DSpace on 2018-11-26T17:55:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-02-01. Added 1 bitstream(s) on 2019-10-09T18:27:53Z : No. of bitstreams: 1 S0034-89102016000200306.pdf: 419935 bytes, checksum: d7fa2f48d7b9e477b060d8abf7ad79c6 (MD5) Brazilian Department of Science and Technology at the Secretariat of Science and Technology Strategic Inputs of the Ministry of Health (Departamento de Ciencia e Tecnologia da Secretaria de Ciencia e Tecnologia e Insumos Estrategicos do Ministerio da Saude - Decit/SCTIE/MS) Health Fund Sector (Fundo Setorial de Saude - CT-health) at the Ministry of science, Technology and Innovation (Ministerio da Ciencia, Tecnologia e Inovacao - MCTI) FINEP Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) hospital research incentive fund for Clinics in Porto Alegre (fundo de incentivo a Pesquisa do Hospital de Clinicas de Porto Alegre - HCPA) OBJECTIVE: To estimate the prevalence of arterial hypertension and obesity and the population attributable fraction of hypertension that is due to obesity in Brazilian adolescents. METHODS: Data from participants in the Brazilian Study of Cardiovascular Risks in Adolescents (ERICA), which was the first national school-based, cross-section study performed in Brazil were evaluated. The sample was divided into 32 geographical strata and clusters from 32 schools and classes, with regional and national representation. Obesity was classified using the body mass index according to age and sex. Arterial hypertension was defined when the average systolic or diastolic blood pressure was greater than or equal to the 95th percentile of the reference curve. Prevalences and 95% confidence intervals (95% CI) of arterial hypertension and obesity, both on a national basis and in the macro-regions of Brazil, were estimated by sex and age group, as were the fractions of hypertension attributable to obesity in the population. RESULTS: We evaluated 73,399 students, 55.4% female, with an average age of 14.7 years (SD = 1.6). The prevalence of hypertension was 9.6% (95% CI 9.0-10.3); with the lowest being in the North, 8.4% (95% CI 7.7-9.2) and Northeast regions, 8.4% (95% CI 7.6-9.2), and the highest being in the South, 12.5% (95% CI 11.0-14.2). The prevalence of obesity was 8.4% (95% CI 7.9-8.9), which was lower in the North region and higher in the South region. The prevalences of arterial hypertension and obesity were higher in males. Obese adolescents presented a higher prevalence of hypertension, 28.4% (95% CI 25.5-31.2), than overweight adolescents, 15.4% (95% CI 17.0-13.8), or eutrophic adolescents, 6.3% (95% CI 5.6-7.0). The fraction of hypertension attributable to obesity was 17.8%. CONCLUSIONS: ERICA was the first nationally representative Brazilian study providing prevalence estimates of hypertension in adolescents. Regional and sex differences were observed. The study indicates that the control of obesity would lower the prevalence of hypertension among Brazilian adolescents by 1/5. Univ Fed Rio de Janeiro, Inst Estudos Saude Colet, Rio De Janeiro, RJ, Brazil Fundacao Oswaldo Cruz, Escola Nacl Saude Publ Sergio Arouca, Dept Epidemiol & Metodos Quantitat Saude, Rio De Janeiro, RJ, Brazil Univ Estado Rio de Janeiro, Nucleo Estudos Saude Adolescente, Fac Ciencia Med, BR-20550011 Rio De Janeiro, RJ, Brazil Univ Estado Rio de Janeiro, Inst Med Social, Programa Posgrad Saude Colet, BR-20550011 Rio De Janeiro, RJ, Brazil Minist Saude, Secretaria Vigilancia Saude, Dept Vigilancia Doencas & Agravos Nao Transmiss &, Brasilia, DF, Brazil Univ Fed Rio de Janeiro, Inst Nutr Josue de Castro, Rio De Janeiro, RJ, Brazil Univ Fed Rio Grande do Sul, Fac Med, Dept Med Interna, Porto Alegre, RS, Brazil Hosp Clin Porto Alegre, Serv Endocrinol, Porto Alegre, RS, Brazil Fundacao Inst Brasileiro Geog & Estat, Escola Nacl Ciencias Estat, Rio De Janeiro, RJ, Brazil Fed Univ Para, Inst Ciencias Saude, BR-66059 Belem, Para, Brazil Univ Sao Paulo, Dept Enfermagem Saude Colet, Sao Paulo, SP, Brazil Univ Estadual Feira de Santana, Dept Saude, Feira De Santana, BA, Brazil Univ Fed Rio de Janeiro, Programa Posgrad Saude Colet, Rio De Janeiro, RJ, Brazil Univ Estado Rio de Janeiro, Dept Nutr, BR-20550011 Rio De Janeiro, RJ, Brazil Univ Fed Minas Gerais, Hosp Clin, Belo Horizonte, MG, Brazil Univ Estado Rio de Janeiro, Inst Nutr, Ctr Biomed, BR-20550011 Rio De Janeiro, RJ, Brazil Univ Fed Amapa, Macapa, AP, Brazil Inst Fed Educ Ciencia & Tecnol Tocantins, Palmas, TO, Brazil Univ Fed Amazonas, Fac Educ Fis & Fisioterapia, Manaus, Amazonas, Brazil Univ Fed Espirito Santo, Dept Enfermagem, Vitoria, ES, Brazil Univ Fed Santa Catarina, Ctr Ciencias Saude, Dept Nutr, Florianopolis, SC, Brazil Univ Fed Rio Grande do Norte, Ctr Biociencias, Dept Morfol, BR-59072970 Natal, RN, Brazil Univ Fed Mato Grosso, Dept Saude Colet, Inst Saude Colet, Cuiaba, MT, Brazil Univ Fed Bahia, Hosp Ana Neri, Salvador, BA, Brazil Pontificia Univ Catolica Parana, Escola Med, Curitiba, Parana, Brazil Univ Fed Pernambuco, Ctr Acad Vitoria, Recife, PE, Brazil Univ Brasilia, Dept Nutr, BR-70910900 Brasilia, DF, Brazil Univ Fed Rondonia, Nucleo Saude, Dept Educ Fis, Porto Velho, RO, Brazil Univ Estadual Campinas, Fac Enfermagem, Campinas, SP, Brazil Univ Fed Piaui, Ctr Ciencias Saude, Dept Nutr, Teresina, PI, Brazil Univ Fed Goias, Fac Med, Goiania, Go, Brazil Univ Fed Maranhao, Univ Hosp, Serv Cardiol, Sao Luis, MA, Brazil Univ Fed Ceara, Fac Med, Dept Saude Comunitaria, Fortaleza, Ceara, Brazil Univ Fed Sergipe, Ctr Ciencias Biol & Saude, Dept Med, Aracaju, SE, Brazil Univ Fed Paraiba, Ctr Ciencias Saude, Dept Nutr, BR-58059900 Joao Pessoa, Paraiba, Brazil Univ Fed Alagoas, Dept Nutr, Maceio, AL, Brazil Univ Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil Univ Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil FINEP: 01090421 CNPq: 2010/565037-2 hospital research incentive fund for Clinics in Porto Alegre (fundo de incentivo a Pesquisa do Hospital de Clinicas de Porto Alegre - HCPA): 405,009/FIPE-2012-7

We sought to determine if increased placental vascular impedance to flow is associated with changes in fetal cardiac function using spatiotemporal image correlation and virtual organ computer-aided analysis.A cross-sectional study was performed in fetuses with umbilical artery pulsatility index95th percentile (abnormal [ABN]). Ventricular volume (end-systole, end-diastole), stroke volume, cardiac output (CO), adjusted CO, and ejection fraction were compared to those of 184 normal fetuses.A total of 34 fetuses were evaluated at a median gestational age of 28.3 (range, 20.6-36.9) weeks. Mean ventricular volumes were lower for ABN than normal cases (end-systole, end-diastole) with a proportionally greater decrease for left ventricular volume (vs right). Mean left and right stroke volume, CO, and adjusted CO were lower for ABN (vs normal) cases. Right ventricular volume, stroke volume, CO, and adjusted CO exceeded the left in ABN fetuses. Mean ejection fraction was greater for ABN than normal cases. Median left ejection fraction was greater (vs right) in ABN fetuses.Increased placental vascular impedance to flow is associated with changes in fetal cardiac function.

The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL).A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters.The following results were found: (1) 184 STIC datasets; (2) with advancing gestation, ventricular volume, SV, CO, and adjusted CO increased, whereas EF decreased; (3) right ventricular (RV) volume was larger than the left ventricular (LV) volume in systole (0.50 vs 0.27 mL; P.001) and diastole (1.20 vs 1.03 mL; P.001); (4) there were no differences between the LV and RV in SV, CO, or adjusted CO; and (5) LV EF was greater than the RV EF (72.2 vs 62.4%; P.001).Normal fetal cardiovascular physiology is characterized by a larger RV volume and a greater LV EF, resulting in similar LV and RV SV and CO.