1,655 results on '"Ghosh, Arun K"'
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202. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry
203. Enantioselective synthesis of (+)-cryptophycin 52 (LY355703), a potent antimitotic antitumor agent
204. An enantioselective synthesis of a MEM-protected aetheramide A derivative
205. FeCl3-catalyzed tandem Prins and Friedel–Crafts cyclization: a highly diastereoselective route to polycyclic ring structures
206. Enantioselective Syntheses of FR901464 and Spliceostatin A: Potent Inhibitors of Spliceosome
207. Bifunctional cinchona alkaloid-squaramide-catalyzed highly enantioselective aza-Michael addition of indolines to α,β-unsaturated ketones
208. Enantioselective synthesis of spiro[cyclohexane-1,3′-indolin]-2′-ones containing multiple stereocenters via organocatalytic Michael/aldol cascade reactions
209. Chapter 13 - Design of the anti-HIV protease inhibitor darunavir
210. Enantioselective Syntheses of (-)-Alloyohimbane and (-)-Yohimbane by an Efficient Enzymatic Desymmetrization Process
211. Benzimidazole-Based FabI Inhibitors: A Promising Novel Scaffold for Anti-staphylococcal Drug Development
212. Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation
213. Correction to Enantioselective Total Synthesis of (+)-Amphirionin-4
214. Enantioselective Synthesis of Both Epimers at C-21 in the Proposed Structure of Cytotoxic Macrolide Callyspongiolide
215. ChemInform Abstract: Stereoselective Synthesis of Substituted Oxocene Cores by Lewis Acid Promoted Cyclization.
216. Defining Viral Defective Ribosomal Products: Standard and Alternative Translation Initiation Events Generate a Common Peptide from Influenza A Virus M2 and M1 mRNAs
217. Enantioselective Total Synthesis of (+)-Amphirionin-4
218. Development of an efficient structure‐based drug discovery platform for BACE1 Inhibitors for the treatment of Alzheimer's Disease
219. C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir
220. Stereoselective Synthesis of Substituted Oxocene Cores by Lewis Acid Promoted Cyclization
221. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS
222. Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
223. Achmatowicz reaction and its application in the syntheses of bioactive molecules
224. Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes
225. Design, synthesis and in vitro splicing inhibition of desmethyl and carba-derivatives of herboxidiene
226. Enantioselective total synthesis and structural assignment of callyspongiolide
227. Enantioselective Synthesis of a Cyclopropane Derivative of Spliceostatin A and Evaluation of Bioactivity.
228. Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition.
229. Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and Its Methyl Ester.
230. Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2′ Ligands of Darunavir.
231. Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitors
232. A tandem olefin migration and Prins cyclization using Cu(OTf)2–bisphosphine complexes: an improved synthesis of functionalized tetrahydropyrans
233. Synthesis of functionalized 4-methylenetetrahydropyrans by oxidative activation of cinnamyl or benzyl ethers
234. Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation.
235. Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors
236. Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Studies
237. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro)
238. Prospects of β‐Secretase Inhibitors for the Treatment of Alzheimer’s Disease
239. Structure-Based Design of Potent HIV-1 Protease Inhibitors with Modified P1-Biphenyl Ligands: Synthesis, Biological Evaluation, and Enzyme–Inhibitor X-ray Structural Studies
240. Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20
241. Novel Protease Inhibitors (PIs) Containing Macrocyclic Components and 3(R),3a(S),6a(R)-bis-Tetrahydrofuranylurethane That Are Potent against Multi-PI-Resistant HIV-1 Variants In Vitro▿
242. A Novel Tricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor, GRL-0739, Effectively Inhibits the Replication of Multidrug-Resistant HIV-1 Variants and Has a Desirable Central Nervous System Penetration Property In Vitro
243. Insights into the Mechanism of Inhibition of CXCR4: Identification of Piperidinylethanamine Analogs as Anti-HIV-1 Inhibitors
244. ChemInform Abstract: A Convergent Synthesis of Carbocyclic Sinefungin (Ia) and Its C-5 Epimer (Ib).
245. Inhibitor Recognition Specificity of MERS-CoV Papain-like Protease May Differ from That of SARS-CoV
246. Organic Carbamates in Drug Design and Medicinal Chemistry
247. Characterization of a Drosophila Ortholog of the Cdc7 Kinase
248. ChemInform Abstract: FeCl3-Catalyzed Tandem Prins and Friedel-Crafts Cyclization: A Highly Diastereoselective Route to Polycyclic Ring Structures.
249. Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands
250. Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs.
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