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Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, From the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO ; Department of Internal Medicine, Saint Louis University School of Medicine; 1402 South Grand Blvd., St. Louis, MO 63104, New England Research Institutes, Watertown, MA, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA ; Department of Medicine, Harvard Medical School, Boston, MA, Liver Institute of Virginia, Bon Secours Health System, Newport News, VA, Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD ; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Department of Medicine, University of Connecticut Health Center, Farmington, CT ; Carolinas Medical Center,Charlotte, NC, Division of Virology, Department of Laboratory Medicine, University of Washington, Seattle, WA, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology, University of California, Irvine, Irvine, CA ; Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Bisceglie, Adrian M., Stoddard, Anne M., Dienstag, Jules L., Shiffman, Mitchell L., Seeff, Leonard B., Bonkovsky, Herbert L., Morishima, Chihiro, Wright, Elizabeth C., Snow, Kristin K., Lee, William M., Fontana, Robert J., Morgan, Timothy R., Ghany, Marc G., Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, From the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO ; Department of Internal Medicine, Saint Louis University School of Medicine; 1402 South Grand Blvd., St. Louis, MO 63104, New England Research Institutes, Watertown, MA, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA ; Department of Medicine, Harvard Medical School, Boston, MA, Liver Institute of Virginia, Bon Secours Health System, Newport News, VA, Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD ; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Department of Medicine, University of Connecticut Health Center, Farmington, CT ; Carolinas Medical Center,Charlotte, NC, Division of Virology, Department of Laboratory Medicine, University of Washington, Seattle, WA, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology, University of California, Irvine, Irvine, CA ; Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Bisceglie, Adrian M., Stoddard, Anne M., Dienstag, Jules L., Shiffman, Mitchell L., Seeff, Leonard B., Bonkovsky, Herbert L., Morishima, Chihiro, Wright, Elizabeth C., Snow, Kristin K., Lee, William M., Fontana, Robert J., Morgan, Timothy R., and Ghany, Marc G.

Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Division of Gastroenterology, University of California Irvine, Irvine, CA ; Gastroenterology Service, Veterans Affairs Long Beach Healthcare System, Long Beach, CA ; fax: 562-826-5436 ; VA Long Beach Healthcare System???11 (GI), 5901 East Seventh Street, Long Beach, CA 90822, Liver Diseases Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, New England Research Institutes, Watertown, MA, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Division of Gastroenterology and Hepatology, University of Colorado at Denver and Health Sciences Center, Denver, CO, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, Departments of Medicine and Molecular and Structural Biology and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, and the Department of Medicine, Harvard Medical School, Boston, MA, Division of Virology, Department of Laboratory Medicine, University of Washington, Seattle, WA, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Morgan, Timothy R., Ghany, Marc G., Kim, Hae-Young, Snow, Kristin K., Shiffman, Mitchell L., De Santo, Jennifer L., Lee, William M., Di Bisceglie, Adrian M., Bonkovsky, Herbert L., Dienstag, Jules L., Morishima, Chihiro, Lindsay, Karen L., Lok, Anna S. F., Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Division of Gastroenterology, University of California Irvine, Irvine, CA ; Gastroenterology Service, Veterans Affairs Long Beach Healthcare System, Long Beach, CA ; fax: 562-826-5436 ; VA Long Beach Healthcare System???11 (GI), 5901 East Seventh Street, Long Beach, CA 90822, Liver Diseases Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, New England Research Institutes, Watertown, MA, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Division of Gastroenterology and Hepatology, University of Colorado at Denver and Health Sciences Center, Denver, CO, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, Departments of Medicine and Molecular and Structural Biology and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, and the Department of Medicine, Harvard Medical School, Boston, MA, Division of Virology, Department of Laboratory Medicine, University of Washington, Seattle, WA, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Morgan, Timothy R., Ghany, Marc G., Kim, Hae-Young, Snow, Kristin K., Shiffman, Mitchell L., De Santo, Jennifer L., Lee, William M., Di Bisceglie, Adrian M., Bonkovsky, Herbert L., Dienstag, Jules L., Morishima, Chihiro, Lindsay, Karen L., and Lok, Anna S. F.

Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Division of Gastroenterology, University of California - Irvine, Irvine, CA, and Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Departments of Medicine and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, and Carolinas Medical Center, Charlotte, NC, New England Research Institutes, Watertown, MA, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Core Genotyping Facility, NCI/Division of Cancer Epidemiology and Genetics, Advanced Technology Program, SAIC-Frederick Inc., NCI-Frederick, Frederick, MD, Department of Medicine, Johns Hopkins University, Baltimore, MD, Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC-Frederick Inc., NCI-Frederick Inc., Frederick, MD, Computer Sciences Corp., Rockville, MD, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, Gastrointestinal Unit, Medical Services, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston, MA, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD ; fax: 301-480-1917. ; 6120 Executive Boulevard, Room 6111, MSC 7246, Rockville, MD 20892, Welzel, Tania Mara, Morgan, Timothy R., Bonkovsky, Herbert L., Naishadham, Deepa, Pfeiffer, Ruth M., Wright, Elizabeth C., Hutchinson, Amy A., Crenshaw, Andrew T., Bashirova, Arman, Carrington, Mary, Dotrang, Myhanh, Sterling, Richard K., Lindsay, Karen L., Fontana, Robert J., Lee, William M., Di Bisceglie, Adrian M., Ghany, Marc G., Gretch, David R., Chanock, Stephen J., Chung, Raymond T., O'Brien, Thomas R., Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Division of Gastroenterology, University of California - Irvine, Irvine, CA, and Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Departments of Medicine and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, and Carolinas Medical Center, Charlotte, NC, New England Research Institutes, Watertown, MA, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Core Genotyping Facility, NCI/Division of Cancer Epidemiology and Genetics, Advanced Technology Program, SAIC-Frederick Inc., NCI-Frederick, Frederick, MD, Department of Medicine, Johns Hopkins University, Baltimore, MD, Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC-Frederick Inc., NCI-Frederick Inc., Frederick, MD, Computer Sciences Corp., Rockville, MD, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, Gastrointestinal Unit, Medical Services, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston, MA, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD ; fax: 301-480-1917. ; 6120 Executive Boulevard, Room 6111, MSC 7246, Rockville, MD 20892, Welzel, Tania Mara, Morgan, Timothy R., Bonkovsky, Herbert L., Naishadham, Deepa, Pfeiffer, Ruth M., Wright, Elizabeth C., Hutchinson, Amy A., Crenshaw, Andrew T., Bashirova, Arman, Carrington, Mary, Dotrang, Myhanh, Sterling, Richard K., Lindsay, Karen L., Fontana, Robert J., Lee, William M., Di Bisceglie, Adrian M., Ghany, Marc G., Gretch, David R., Chanock, Stephen J., Chung, Raymond T., and O'Brien, Thomas R.

Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA ; fax: 206-744-9858. ; Department of Laboratory Medicine, University of Washington, Box 359690, Seattle, WA 98104, Division of Gastroenterology, University of California???Irvine, Irvine, CA, and Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Division of Digestive Diseases and Nutrition, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Section of Hepatology, Division of Gastroenterology and Hepatology, University of Colorado School of Medicine, Denver, CO, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Gastrointestinal Unit (Medical Services), Massachusetts General Hospital and the Department of Medicine, Harvard Medical School, Boston, MA, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, New England Research Institutes, Watertown, MA, Morishima, Chihiro, Morgan, Timothy R., Everhart, James E., Wright, Elizabeth C., Apodaca, Minjun C., Gretch, David R., Shiffman, Mitchell L., Everson, Gregory T., Lindsay, Karen L., Lee, William M., Lok, Anna S. F., Dienstag, Jules L., Ghany, Marc G., Curto, Teresa M., Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA ; fax: 206-744-9858. ; Department of Laboratory Medicine, University of Washington, Box 359690, Seattle, WA 98104, Division of Gastroenterology, University of California???Irvine, Irvine, CA, and Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, Division of Digestive Diseases and Nutrition, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, Section of Hepatology, Division of Gastroenterology and Hepatology, University of Colorado School of Medicine, Denver, CO, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, Gastrointestinal Unit (Medical Services), Massachusetts General Hospital and the Department of Medicine, Harvard Medical School, Boston, MA, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, New England Research Institutes, Watertown, MA, Morishima, Chihiro, Morgan, Timothy R., Everhart, James E., Wright, Elizabeth C., Apodaca, Minjun C., Gretch, David R., Shiffman, Mitchell L., Everson, Gregory T., Lindsay, Karen L., Lee, William M., Lok, Anna S. F., Dienstag, Jules L., Ghany, Marc G., and Curto, Teresa M.

Division of Gastroenterology, University of Michigan, Ann Arbor, MI ; fax: 734-936-7392 ; Division of Gastroenterology, University of Michigan Health System, 3912 Taubman Center, Ann Arbor, MI 48109-0362, INSERM, U271; Universit?? Lyon I; Hospices Civils de Lyon, Lyon, France, Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia, Liver Diseases Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, French National Reference Center for Viral Hepatitis B, C and delta, Department of Virology and INSERM U841, Hopital Henri Mondor, Universite Paris 12, Creteil, France, Liver Research Unit, Chang Gung University and Memorial Hospital, Taipei, Taiwan, Department of Clinical Molecular Informative Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, Theoretical Biology and Biophysics Group (T-10), Los Alamos National Laboratory, Los Alamos, NM, Lok, Anna S., Zoulim, Fabien, Locarnini, Stephen, Bartholomeusz, Angeline, Ghany, Marc G., Pawlotsky, Jean-Michel, Liaw, Yun-Fan, Mizokami, Masashi, Kuiken, Carla, Division of Gastroenterology, University of Michigan, Ann Arbor, MI ; fax: 734-936-7392 ; Division of Gastroenterology, University of Michigan Health System, 3912 Taubman Center, Ann Arbor, MI 48109-0362, INSERM, U271; Universit?? Lyon I; Hospices Civils de Lyon, Lyon, France, Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia, Liver Diseases Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, French National Reference Center for Viral Hepatitis B, C and delta, Department of Virology and INSERM U841, Hopital Henri Mondor, Universite Paris 12, Creteil, France, Liver Research Unit, Chang Gung University and Memorial Hospital, Taipei, Taiwan, Department of Clinical Molecular Informative Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, Theoretical Biology and Biophysics Group (T-10), Los Alamos National Laboratory, Los Alamos, NM, Lok, Anna S., Zoulim, Fabien, Locarnini, Stephen, Bartholomeusz, Angeline, Ghany, Marc G., Pawlotsky, Jean-Michel, Liaw, Yun-Fan, Mizokami, Masashi, and Kuiken, Carla

Department of Internal Medicine, University of Michigan, Ann Arbor, MI ; fax: 734-936-7392 ; 3912 Taubman Center, Ann Arbor, MI 48109-0362, National Cancer Institute, Bethesda, MD, University of Pittsburgh, Pittsburgh, PA, University of California San Francisco, San Francisco, CA, Beth Israel Deaconess Medical Center, Boston, MA, University of Miami, Miami, FL, National Institutes of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, Fontana, Robert J., Kleiner, David E., Bilonick, Richard, Terrault, Norah, Afdhal, Nezam, Belle, Steven H., Jeffers, Lennox J., Ramcharran, Darmendra, Ghany, Marc G., Hoofnagle, Jay H., Department of Internal Medicine, University of Michigan, Ann Arbor, MI ; fax: 734-936-7392 ; 3912 Taubman Center, Ann Arbor, MI 48109-0362, National Cancer Institute, Bethesda, MD, University of Pittsburgh, Pittsburgh, PA, University of California San Francisco, San Francisco, CA, Beth Israel Deaconess Medical Center, Boston, MA, University of Miami, Miami, FL, National Institutes of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, Fontana, Robert J., Kleiner, David E., Bilonick, Richard, Terrault, Norah, Afdhal, Nezam, Belle, Steven H., Jeffers, Lennox J., Ramcharran, Darmendra, Ghany, Marc G., and Hoofnagle, Jay H.

From the Section of Gastroenterology and Hepatology, and Hematology and Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana; Chiron Corporation, Emeryville, California; Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Box 0362, 48109, Ann Arbor, Michigan, From the Section of Gastroenterology and Hepatology, and Hematology and Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana; Chiron Corporation, Emeryville, California, Ann Arbor, Sanchez-Pescador, R., Leissinger, C., Lagier, R., Lok, A.S.F., Ghany, Marc G., From the Section of Gastroenterology and Hepatology, and Hematology and Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana; Chiron Corporation, Emeryville, California; Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Box 0362, 48109, Ann Arbor, Michigan, From the Section of Gastroenterology and Hepatology, and Hematology and Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana; Chiron Corporation, Emeryville, California, Ann Arbor, Sanchez-Pescador, R., Leissinger, C., Lagier, R., Lok, A.S.F., and Ghany, Marc G.