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201. Cardiovascular disease in kidney donors: matched cohort study

Author

Garg, Amit X, Meirambayeva, Aizhan, Huang, Anjie, Kim, Joseph, Prasad, G V Ramesh, Knoll, Greg, Boudville, Neil, Lok, Charmaine, McFarlane, Philip, Karpinski, Martin, Storsley, Leroy, Klarenbach, Scott, Lam, Ngan, Thomas, Sonia M, Dipchand, Christine, Reese, Peter, Doshi, Mona, Gibney, Eric, Taub, Ken, and Young, Ann

Published
2012

204. Pre-Operative Kidney Biomarkers and Risks for Death, Cardiovascular and Chronic Kidney Disease Events after Cardiac Surgery: The TRIBE-AKI Study

Author

Parikh, Chirag R., primary, Vasquez-Rios, George, additional, Moledina, Dennis G., additional, Jia, Yaqi, additional, McArthur, Eric, additional, Mansour, Sherry G., additional, Thiessen-Philbrook, Heather, additional, Shlipak, Michael G., additional, Koyner, Jay L., additional, Garg, Amit X., additional, and Coca, Steven G., additional

Published
2022
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205. Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada

Author

Oliver, Matthew J., primary, Thomas, Doneal, additional, Balamchi, Shabnam, additional, Ip, Jane, additional, Naylor, Kyla, additional, Dixon, Stephanie N., additional, McArthur, Eric, additional, Kwong, Jeff, additional, Perl, Jeffrey, additional, Atiquzzaman, Mohammad, additional, Singer, Joel, additional, Yeung, Angie, additional, Hladunewich, Michelle, additional, Yau, Kevin, additional, Garg, Amit X., additional, Leis, Jerome A., additional, Levin, Adeera, additional, Krajden, Mel, additional, and Blake, Peter G., additional

Published
2022
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206. Multifaceted Intervention to Increase the Use of Home Dialysis

Author

Manns, Braden J., primary, Garg, Amit X., additional, Sood, Manish M., additional, Ferguson, Thomas, additional, Kim, S. Joseph, additional, Naimark, David, additional, Nesrallah, Gihad E., additional, Soroka, Steven D., additional, Beaulieu, Monica, additional, Dixon, Stephanie N., additional, Alam, Ahsan, additional, Allu, Selina, additional, and Tangri, Navdeep, additional

Published
2022
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209. Additional file 9 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 9. POISE-3 informed consent form template (English).

Published
2022
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210. sj-docx-2-cjk-10.1177_20543581221129442 – Supplemental material for The Living Kidney Donor Safety Study: Protocol of a Prospective Cohort Study

Author

Garg, Amit X., Arnold, Jennifer B., Cuerden, Meaghan, Dipchand, Christine, Feldman, Liane S., Gill, John S., Karpinski, Martin, Klarenbach, Scott, Knoll, Greg A., Lok, Charmaine, Miller, Matthew, Monroy-Cuadros, Mauricio, Nguan, Christopher, Prasad, G. V. Ramesh, Sontrop, Jessica M., Storsley, Leroy, and Boudville, Neil

Subjects
Medicine
Abstract

Supplemental material, sj-docx-2-cjk-10.1177_20543581221129442 for The Living Kidney Donor Safety Study: Protocol of a Prospective Cohort Study by Amit X. Garg, Jennifer B. Arnold, Meaghan Cuerden, Christine Dipchand, Liane S. Feldman, John S. Gill, Martin Karpinski, Scott Klarenbach, Greg A. Knoll, Charmaine Lok, Matthew Miller, Mauricio Monroy-Cuadros, Christopher Nguan, G. V. Ramesh Prasad, Jessica M. Sontrop, Leroy Storsley and Neil Boudville in Canadian Journal of Kidney Health and Disease

Published
2022
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211. Additional file 9 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Author

Al-Jaishi, Ahmed A., Taljaard, Monica, Al-Jaishi, Melissa D., Abdullah, Sheikh S., Thabane, Lehana, Devereaux, P. J., Dixon, Stephanie N., and Garg, Amit X.

Abstract

Additional file 9. Details and results for applying our model on a dialysis-related dataset. Table S1. Number of relevant articles retrieved with and without machine learning algorithm using the demonstration dataset (n=882 records). The research objective was to review CRTs in the hemodialysis setting to report key methodological and ethical issues.

Published
2022
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213. Additional file 1 of Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1): a pragmatic stepped-wedge, cluster randomized controlled registry trial

Author

Li, Alvin Ho-ting, Garg, Amit X., Grimshaw, Jeremy M., Prakash, Versha, Dunnett, Alexie J., Dixon, Stephanie N., Taljaard, Monica, Mitchell, Joanna, Naylor, Kyla L., Faulds, Cathy, Bevan, Rachel, Getchell, Leah, Knoll, Greg, Kim, S. Joseph, Sontrop, Jessica, Tong, Allison, Bjerre, Lise M., Hyjek, Karyn, Currie, Donna, Edwards, Susan, Sullivan, Mike, Harvey-Rioux, Linda, and Presseau, Justin

Subjects
Data_FILES
Abstract

Additional file 1.

Published
2022
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214. sj-docx-2-cjk-10.1177_20543581221084502 – Supplemental material for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

Author

Yohanna, Seychelle, Wilson, Mackenzie, Naylor, Kyla L., Garg, Amit X., Sontrop, Jessica M., Belenko, Dmitri, Elliott, Lori, McKenzie, Susan, Macanovic, Sara, Mucsi, Istvan, Patzer, Rachel, Voronin, Irina, Lui, Iris, Blake, Peter G., Waterman, Amy D., Treleaven, Darin, and Presseau, Justin

Subjects
Medicine
Abstract

Supplemental material, sj-docx-2-cjk-10.1177_20543581221084502 for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial by Seychelle Yohanna, Mackenzie Wilson, Kyla L. Naylor, Amit X. Garg, Jessica M. Sontrop, Dmitri Belenko, Lori Elliott, Susan McKenzie, Sara Macanovic, Istvan Mucsi, Rachel Patzer, Irina Voronin, Iris Lui, Peter G. Blake, Amy D. Waterman, Darin Treleaven and Justin Presseau in Canadian Journal of Kidney Health and Disease

Published
2022
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215. Additional file 7 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Author

Al-Jaishi, Ahmed A., Taljaard, Monica, Al-Jaishi, Melissa D., Abdullah, Sheikh S., Thabane, Lehana, Devereaux, P. J., Dixon, Stephanie N., and Garg, Amit X.

Abstract

Additional file 7: Fig. S3. Probability plot for the CRTs in the first external data classified as a CRT (Figure A, 665 CRTs) and non-CRTs classified as a CRT (Figure B, 1251 non-CRTs). The x-axis depicts the stacked ensemble model's prediction of the article being classified as a CRT. The y-axis represents the proportion of all documents that had the corresponding probability.

Published
2022
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216. Effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury : a clinical research protocol for a substudy of the POISE-3 randomized clinical trial

Author

Garg, Amit X., Polanczyk, Carisi Anne, and Devereaux, Philip J.

Subjects
Pressão arterial, Antihypertensive medication, Anti-hipertensivos, Noncardiac surgery, Hipotensão, Hypotension, Injúria renal aguda, Acute kidney injury, Mean arterial pressure
Abstract

Background: Most patients who take antihypertensive medications continue taking them on the morning of surgery and during the perioperative period. However, growing evidence suggests this practice may contribute to perioperative hypotension and a higher risk of complications. This protocol describes an acute kidney injury substudy of the Perioperative Ischemic Evaluation-3 (POISE-3) trial, which is testing the effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy in patients undergoing noncardiac surgery. Objective: To conduct a substudy of POISE-3 to determine whether a perioperative hypotension-avoidance strategy reduces the risk of acute kidney injury compared with a hypertension-avoidance strategy. Design: Randomized clinical trial with 1:1 randomization to the intervention (a perioperative hypotension-avoidance strategy) or control (a hypertension-avoidance strategy). Intervention: If the presurgery systolic blood pressure (SBP) is

Published
2022

217. Additional file 7 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 7. POISE-3 interim analyses.

Published
2022
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218. sj-docx-1-cjk-10.1177_20543581221129442 – Supplemental material for The Living Kidney Donor Safety Study: Protocol of a Prospective Cohort Study

Author

Garg, Amit X., Arnold, Jennifer B., Cuerden, Meaghan, Dipchand, Christine, Feldman, Liane S., Gill, John S., Karpinski, Martin, Klarenbach, Scott, Knoll, Greg A., Lok, Charmaine, Miller, Matthew, Monroy-Cuadros, Mauricio, Nguan, Christopher, Prasad, G. V. Ramesh, Sontrop, Jessica M., Storsley, Leroy, and Boudville, Neil

Subjects
Medicine
Abstract

Supplemental material, sj-docx-1-cjk-10.1177_20543581221129442 for The Living Kidney Donor Safety Study: Protocol of a Prospective Cohort Study by Amit X. Garg, Jennifer B. Arnold, Meaghan Cuerden, Christine Dipchand, Liane S. Feldman, John S. Gill, Martin Karpinski, Scott Klarenbach, Greg A. Knoll, Charmaine Lok, Matthew Miller, Mauricio Monroy-Cuadros, Christopher Nguan, G. V. Ramesh Prasad, Jessica M. Sontrop, Leroy Storsley and Neil Boudville in Canadian Journal of Kidney Health and Disease

Published
2022
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221. Additional file 10 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Subjects
ComputingMilieux_THECOMPUTINGPROFESSION, Data_FILES, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

Additional file 10. List of investigators and committees.

Published
2022
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223. Additional file 8 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 8. POISE-3 organizational structure and oversight of trial conduct.

Published
2022
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224. sj-pdf-1-cjk-10.1177_20543581221131201 – Supplemental material for Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD): Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial

Author

Dixon, Stephanie N., Naylor, Kyla L., Yohanna, Seychelle, McKenzie, Susan, Belenko, Dmitri, Blake, Peter G, Coghlan, Candice, Cooper, Rebecca, Elliott, Lori, Getchell, Leah, Ki, Vincent, Mucsi, Istvan, Nesrallah, Gihad, Patzer, Rachel E., Presseau, Justin, Reich, Marian, Sontrop, Jessica M., Treleaven, Darin, Waterman, Amy D., Zaltzman, Jeffrey, and Garg, Amit X.

Subjects
Medicine
Abstract

Supplemental material, sj-pdf-1-cjk-10.1177_20543581221131201 for Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD): Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial by Stephanie N. Dixon, Kyla L. Naylor, Seychelle Yohanna, Susan McKenzie, Dmitri Belenko, Peter G Blake, Candice Coghlan, Rebecca Cooper, Lori Elliott, Leah Getchell, Vincent Ki, Istvan Mucsi, Gihad Nesrallah, Rachel E. Patzer, Justin Presseau, Marian Reich, Jessica M. Sontrop, Darin Treleaven, Amy D. Waterman, Jeffrey Zaltzman and Amit X. Garg in Canadian Journal of Kidney Health and Disease

Published
2022
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225. sj-docx-2-cjk-10.1177_20543581221111712 – Supplemental material for Using Administrative Health Care Databases to Identify Patients With End-Stage Kidney Disease With No Recorded Contraindication to Receiving a Kidney Transplant

Author

Wang, Carol, Naylor, Kyla L., Luo, Bin, Bota, Sarah E., Dixon, Stephanie N., Yohanna, Seychelle, Treleaven, Darin, Elliott, Lori, and Garg, Amit X.

Subjects
Medicine
Abstract

Supplemental material, sj-docx-2-cjk-10.1177_20543581221111712 for Using Administrative Health Care Databases to Identify Patients With End-Stage Kidney Disease With No Recorded Contraindication to Receiving a Kidney Transplant by Carol Wang, Kyla L. Naylor, Bin Luo, Sarah E. Bota, Stephanie N. Dixon, Seychelle Yohanna, Darin Treleaven, Lori Elliott and Amit X. Garg in Canadian Journal of Kidney Health and Disease

Published
2022
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226. Additional file 5 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 5. POISE-3 tertiary outcomes.

Published
2022
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228. sj-docx-1-cjk-10.1177_20543581211069225 ��� Supplemental material for Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial

Author

Garg, Amit X., Cuerden, Meaghan, Aguado, Hector, Amir, Mohammed, Belley-Cote, Emilie P., Bhatt, Keyur, Biccard, Bruce M., Borges, Flavia K., Chan, Matthew, Conen, David, Duceppe, Emmanuelle, Efremov, Sergey, Eikelboom, John, Fleischmann, Edith, Giovanni, Landoni, Gross, Peter, Jayaram, Raja, Kirov, Mikhail, Kleinlugtenbelt, Ydo, Kurz, Andrea, Lamy, Andre, Leslie, Kate, Likhvantsev, Valery, Lomivorotov, Vladimir, Marcucci, Maura, Mart��nez-Zapata, Maria Jos��, McGillion, Michael, McIntyre, William, Meyhoff, Christian, Ofori, Sandra, Painter, Thomas, Paniagua, Pilar, Parikh, Chirag, Parlow, Joel, Patel, Ameen, Polanczyk, Carisi, Richards, Toby, Roshanov, Pavel, Schmartz, Denis, Sessler, Daniel, Short, Tim, Sontrop, Jessica M., Spence, Jessica, Srinathan, Sadeesh, Stillo, David, Szczeklik, Wojciech, Tandon, Vikas, Torres, David, Van Helder, Thomas, Vincent, Jessica, Wang, C. Y., Wang, Michael, Whitlock, Richard, Wittmann, Maria, Xavier, Denis, and Devereaux, P. J.

Subjects
Medicine
Abstract

Supplemental material, sj-docx-1-cjk-10.1177_20543581211069225 for Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial by Amit X. Garg, Meaghan Cuerden, Hector Aguado, Mohammed Amir, Emilie P. Belley-Cote, Keyur Bhatt, Bruce M. Biccard, Flavia K. Borges, Matthew Chan, David Conen, Emmanuelle Duceppe, Sergey Efremov, John Eikelboom, Edith Fleischmann, Landoni Giovanni, Peter Gross, Raja Jayaram, Mikhail Kirov, Ydo Kleinlugtenbelt, Andrea Kurz, Andre Lamy, Kate Leslie, Valery Likhvantsev, Vladimir Lomivorotov, Maura Marcucci, Maria Jos�� Mart��nez-Zapata, Michael McGillion, William McIntyre, Christian Meyhoff, Sandra Ofori, Thomas Painter, Pilar Paniagua, Chirag Parikh, Joel Parlow, Ameen Patel, Carisi Polanczyk, Toby Richards, Pavel Roshanov, Denis Schmartz, Daniel Sessler, Tim Short, Jessica M. Sontrop, Jessica Spence, Sadeesh Srinathan, David Stillo, Wojciech Szczeklik, Vikas Tandon, David Torres, Thomas Van Helder, Jessica Vincent, C. Y. Wang, Michael Wang, Richard Whitlock, Maria Wittmann, Denis Xavier and P. J. Devereaux in Canadian Journal of Kidney Health and Disease

Published
2022
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229. sj-docx-1-cjk-10.1177_20543581221084502 – Supplemental material for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

Author

Yohanna, Seychelle, Wilson, Mackenzie, Naylor, Kyla L., Garg, Amit X., Sontrop, Jessica M., Belenko, Dmitri, Elliott, Lori, McKenzie, Susan, Macanovic, Sara, Mucsi, Istvan, Patzer, Rachel, Voronin, Irina, Lui, Iris, Blake, Peter G., Waterman, Amy D., Treleaven, Darin, and Presseau, Justin

Subjects
Medicine
Abstract

Supplemental material, sj-docx-1-cjk-10.1177_20543581221084502 for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial by Seychelle Yohanna, Mackenzie Wilson, Kyla L. Naylor, Amit X. Garg, Jessica M. Sontrop, Dmitri Belenko, Lori Elliott, Susan McKenzie, Sara Macanovic, Istvan Mucsi, Rachel Patzer, Irina Voronin, Iris Lui, Peter G. Blake, Amy D. Waterman, Darin Treleaven and Justin Presseau in Canadian Journal of Kidney Health and Disease

Published
2022
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231. sj-docx-4-cjk-10.1177_20543581221084502 – Supplemental material for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

Author

Yohanna, Seychelle, Wilson, Mackenzie, Naylor, Kyla L., Garg, Amit X., Sontrop, Jessica M., Belenko, Dmitri, Elliott, Lori, McKenzie, Susan, Macanovic, Sara, Mucsi, Istvan, Patzer, Rachel, Voronin, Irina, Lui, Iris, Blake, Peter G., Waterman, Amy D., Treleaven, Darin, and Presseau, Justin

Subjects
Medicine
Abstract

Supplemental material, sj-docx-4-cjk-10.1177_20543581221084502 for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial by Seychelle Yohanna, Mackenzie Wilson, Kyla L. Naylor, Amit X. Garg, Jessica M. Sontrop, Dmitri Belenko, Lori Elliott, Susan McKenzie, Sara Macanovic, Istvan Mucsi, Rachel Patzer, Irina Voronin, Iris Lui, Peter G. Blake, Amy D. Waterman, Darin Treleaven and Justin Presseau in Canadian Journal of Kidney Health and Disease

Published
2022
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232. sj-docx-1-cjk-10.1177_20543581221111712 – Supplemental material for Using Administrative Health Care Databases to Identify Patients With End-Stage Kidney Disease With No Recorded Contraindication to Receiving a Kidney Transplant

Author

Wang, Carol, Naylor, Kyla L., Luo, Bin, Bota, Sarah E., Dixon, Stephanie N., Yohanna, Seychelle, Treleaven, Darin, Elliott, Lori, and Garg, Amit X.

Subjects
Medicine
Abstract

Supplemental material, sj-docx-1-cjk-10.1177_20543581221111712 for Using Administrative Health Care Databases to Identify Patients With End-Stage Kidney Disease With No Recorded Contraindication to Receiving a Kidney Transplant by Carol Wang, Kyla L. Naylor, Bin Luo, Sarah E. Bota, Stephanie N. Dixon, Seychelle Yohanna, Darin Treleaven, Lori Elliott and Amit X. Garg in Canadian Journal of Kidney Health and Disease

Published
2022
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233. sj-docx-3-cjk-10.1177_20543581221084502 – Supplemental material for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

Author

Yohanna, Seychelle, Wilson, Mackenzie, Naylor, Kyla L., Garg, Amit X., Sontrop, Jessica M., Belenko, Dmitri, Elliott, Lori, McKenzie, Susan, Macanovic, Sara, Mucsi, Istvan, Patzer, Rachel, Voronin, Irina, Lui, Iris, Blake, Peter G., Waterman, Amy D., Treleaven, Darin, and Presseau, Justin

Subjects
Medicine
Abstract

Supplemental material, sj-docx-3-cjk-10.1177_20543581221084502 for Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial by Seychelle Yohanna, Mackenzie Wilson, Kyla L. Naylor, Amit X. Garg, Jessica M. Sontrop, Dmitri Belenko, Lori Elliott, Susan McKenzie, Sara Macanovic, Istvan Mucsi, Rachel Patzer, Irina Voronin, Iris Lui, Peter G. Blake, Amy D. Waterman, Darin Treleaven and Justin Presseau in Canadian Journal of Kidney Health and Disease

Published
2022
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234. Additional file 4 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Author

Al-Jaishi, Ahmed A., Taljaard, Monica, Al-Jaishi, Melissa D., Abdullah, Sheikh S., Thabane, Lehana, Devereaux, P. J., Dixon, Stephanie N., and Garg, Amit X.

Abstract

Additional file 4: Description of the gamma and c parameters. Fig. S2. This figure shows the decision boundaries and support vectors for different settings of the regularization parameter (C) and Kernel coefficient (gamma). We used the mglearn package to create this figure [27].

Published
2022
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235. Additional file 3 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 3. Rationale for POISE-3 study dosing regimen of tranexamic acid.

Published
2022
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236. Additional file 6 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author

Marcucci, Maura, Painter, Thomas W., Conen, David, Leslie, Kate, Lomivorotov, Vladimir V., Sessler, Daniel, Chan, Matthew T. V., Borges, Flavia K., Mart��nez Zapata, Maria J., Wang, C. Y., Xavier, Denis, Ofori, Sandra N., Landoni, Giovanni, Efremov, Sergey, Kleinlugtenbelt, Ydo V., Szczeklik, Wojciech, Schmartz, Denis, Garg, Amit X., Short, Timothy G., Wittmann, Maria, Meyhoff, Christian S., Amir, Mohammed, Torres, David, Patel, Ameen, Duceppe, Emmanuelle, Ruetzler, Kurtz, Parlow, Joel L., Tandon, Vikas, Wang, Michael K., Fleischmann, Edith, Polanczyk, Carisi A., Jayaram, Raja, Astrakov, Sergey V., Rao, Mangala, VanHelder, Tomas, Wu, William K. K., Cheong, Chao Chia, Ayad, Sabry, Abubakirov, Marat, Kirov, Mikhail, Bhatt, Keyur, de Nadal, Miriam, Likhvantsev, Valery, Iglesisas, Pilar Paniagua, Aguado, Hector J., McGillion, Michael, Lamy, Andre, Whitlock, Richard P., Roshanov, Pavel, Stillo, David, Copland, Ingrid, Vincent, Jessica, Balasubramanian, Kumar, Bangdiwala, Shrikant I., Biccard, Bruce, Kurz, Andrea, Srinathan, Sadeesh, Petit, Shirley, Eikelboom, John, Richards, Toby, Gross, Peter L., Alfonsi, Pascal, Guyatt, Gordon, Belley-Cote, Emily, Spence, Jessica, McIntyre, William, Yusuf, Salim, and Devereaux, P. J.

Abstract

Additional file 6. POISE-3 outcome definitions.

Published
2022
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240. Macrolide antibiotics and the risk of ventricular arrhythmia in older adults

Author

Trac, Mai H., McArthur, Eric, Jandoc, Racquel, Dixon, Stephanie N., Nash, Danielle M., Hackam, Daniel G., and Garg, Amit X.

Subjects
Arrhythmia -- Risk factors -- Research, Antibiotics -- Complications and side effects -- Research -- Dosage and administration, Health
Abstract

Background: Many respiratory tract infections are treated with macrolide antibiotics. Regulatory agencies warn that these antibiotics increase the risk of ventricular arrhythmia. We examined the 30-day risk of ventricular arrhythmia and all-cause mortality associated with macrolide antibiotics relative to nonmacrolide antibiotics. Methods: We conducted a population-based retrospective cohort study involving older adults (age > 65 yr) with a new prescription for an oral macrolide antibiotic (azithromycin, clarithromycin or erythromycin) in Ontario from 2002 to 2013. Our primary outcome was a hospital encounter with ventricular arrhythmia within 30 days after a new prescription. Our secondary outcome was 30-day all-cause mortality. We matched patients 1:1 using propensity scores to patients prescribed nonmacrolide antibiotics (amoxicillin, cefuroxime or levofloxacin). We used conditional logistic regression to measure the association between macrolide exposure and outcomes, and repeated the analysis in 4 subgroups defined by the presence or absence of chronic kidney disease, congestive heart failure, coronary artery disease and concurrent use of a drug known to prolong the QT interval. Results: Compared with nonmacrolide antibiotics, macrolide antibiotics were not associated with a higher risk of ventricular arrhythmia (0.03% v. 0.03%; relative risk [RR] 1.06, 95% confidence interval [CI] 0.83-1.36) and were associated with a lower risk of all-cause mortality (0.62% v. 0.76%; RR 0.82, 95% CI 0.78-0.86). These associations were similar in all subgroups. Interpretation: Among older adults, macrolide antibiotics were not associated with a higher 30-day risk of ventricular arrhythmia than nonmacrolide antibiotics. These findings suggest that current warnings from the US Food and Drug Administration may be overstated., Macrolide antibiotics (e.g., azithromycin, clarithromycin and erythromycin) are a common class of medication used to treat community-acquired respiratory tract infections. (1-3) In 2010, more than 57 million outpatient prescriptions were [...]

Published
2016
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241. Effects of remote ischemic preconditioning in high-risk patients undergoing cardiac surgery (Remote IMPACT): a randomized controlled trial

Author

Walsh, Michael, Whitlock, Richard, Garg, Amit X., Legare, Jean-Francois, Duncan, Andra E., Zimmerman, Robert, Miller, Scott, Fremes, Stephen, Kieser, Teresa, Karthikeyan, Ganesan, Chan, Matthew, Ho, Anthony, Nasr, Vivian, Vincent, Jessica, Ali, Imtiaz, Lavi, Ronit, Sessler, Daniel I., Kramer, Robert, Gardner, Jeff, Syed, Summer, VanHelder, Tomas, Guyatt, Gordon, Rao-Melacini, Purnima, Thabane, Lehana, and Devereaux, P.J.

Subjects
Heart -- Surgery, Ischemia -- Risk factors -- Care and treatment, Clinical trials -- Usage, Cardiac patients -- Care and treatment -- Health aspects, Health
Abstract

Background: Remote ischemic preconditioning is a simple therapy that may reduce cardiac and kidney injury. We undertook a randomized controlled trial to evaluate the effect of this therapy on markers of heart and kidney injury after cardiac surgery. Methods: Patients at high risk of death within 30 days after cardiac surgery were randomly assigned to undergo remote ischemic preconditioning or a sham procedure after induction of anesthesia. The preconditioning therapy was three 5-minute cycles of thigh ischemia, with 5 minutes of reperfusion between cycles. The sham procedure was identical except that ischemia was not induced. The primary outcome was peak creatine kinase-myocardial band (CK-MB) within 24 hours after surgery (expressed as multiples of the upper limit of normal, with log transformation). The secondary outcome was change in creatinine level within 4 days after surgery (expressed as log-transformed micromoles per litre). Patient-important outcomes were assessed up to 6 months after randomization. Results: We randomly assigned 128 patients to remote ischemic preconditioning and 130 to the sham therapy. There were no significant differences in postoperative CK-MB (absolute mean difference 0.15, 95% confidence interval [CI] -0.07 to 0.36) or creatinine (absolute mean difference 0.06, 95% CI -0.10 to 0.23). Other outcomes did not differ significantly for remote ischemic preconditioning relative to the sham therapy: for myocardial infarction, relative risk (RR) 1.35 (95% CI 0.85 to 2.17); for acute kidney injury, RR 1.10 (95% CI 0.68 to 1.78); for stroke, RR 1.02 (95% CI 0.34 to 3.07); and for death, RR 1.47 (95% CI 0.65 to 3.31). Interpretation: Remote ischemic preconditioning did not reduce myocardial or kidney injury during cardiac surgery. This type of therapy is unlikely to substantially improve patientimportant outcomes in cardiac surgery. Trial registration: ClinicalTrials.gov, no. NCT01071265., Each year, 2 million patients worldwide undergo cardiac surgery. For more than 25% of these patients, the surgery is complicated by myocardial infarction (MI) and/or acute kidney injury, both of [...]

Published
2016
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244. Physician Health Care Visits for Mental Health and Substance Use During the COVID-19 Pandemic in Ontario, Canada

Author

Myran, Daniel T., primary, Cantor, Nathan, additional, Rhodes, Emily, additional, Pugliese, Michael, additional, Hensel, Jennifer, additional, Taljaard, Monica, additional, Talarico, Robert, additional, Garg, Amit X., additional, McArthur, Eric, additional, Liu, Cheng-Wei, additional, Jeyakumar, Nivethika, additional, Simon, Christopher, additional, McFadden, Taylor, additional, Gerin-Lajoie, Caroline, additional, Sood, Manish M., additional, and Tanuseputro, Peter, additional

Published
2022
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246. Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

Author

Yohanna, Seychelle, primary, Wilson, Mackenzie, additional, Naylor, Kyla L., additional, Garg, Amit X., additional, Sontrop, Jessica M., additional, Belenko, Dmitri, additional, Elliott, Lori, additional, McKenzie, Susan, additional, Macanovic, Sara, additional, Mucsi, Istvan, additional, Patzer, Rachel, additional, Voronin, Irina, additional, Lui, Iris, additional, Blake, Peter G., additional, Waterman, Amy D., additional, Treleaven, Darin, additional, and Presseau, Justin, additional

Published
2022
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249. The Living Kidney Donor Safety Study: Protocol of a Prospective Cohort Study

Author

Garg, Amit X., primary, Arnold, Jennifer B., additional, Cuerden, Meaghan, additional, Dipchand, Christine, additional, Feldman, Liane S., additional, Gill, John S., additional, Karpinski, Martin, additional, Klarenbach, Scott, additional, Knoll, Greg A., additional, Lok, Charmaine, additional, Miller, Matthew, additional, Monroy-Cuadros, Mauricio, additional, Nguan, Christopher, additional, Prasad, G. V. Ramesh, additional, Sontrop, Jessica M., additional, Storsley, Leroy, additional, and Boudville, Neil, additional

Published
2022
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250. Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial

Author

Garg, Amit X., primary, Cuerden, Meaghan, additional, Aguado, Hector, additional, Amir, Mohammed, additional, Belley-Cote, Emilie P., additional, Bhatt, Keyur, additional, Biccard, Bruce M., additional, Borges, Flavia K., additional, Chan, Matthew, additional, Conen, David, additional, Duceppe, Emmanuelle, additional, Efremov, Sergey, additional, Eikelboom, John, additional, Fleischmann, Edith, additional, Giovanni, Landoni, additional, Gross, Peter, additional, Jayaram, Raja, additional, Kirov, Mikhail, additional, Kleinlugtenbelt, Ydo, additional, Kurz, Andrea, additional, Lamy, Andre, additional, Leslie, Kate, additional, Likhvantsev, Valery, additional, Lomivorotov, Vladimir, additional, Marcucci, Maura, additional, Martínez-Zapata, Maria José, additional, McGillion, Michael, additional, McIntyre, William, additional, Meyhoff, Christian, additional, Ofori, Sandra, additional, Painter, Thomas, additional, Paniagua, Pilar, additional, Parikh, Chirag, additional, Parlow, Joel, additional, Patel, Ameen, additional, Polanczyk, Carisi, additional, Richards, Toby, additional, Roshanov, Pavel, additional, Schmartz, Denis, additional, Sessler, Daniel, additional, Short, Tim, additional, Sontrop, Jessica M., additional, Spence, Jessica, additional, Srinathan, Sadeesh, additional, Stillo, David, additional, Szczeklik, Wojciech, additional, Tandon, Vikas, additional, Torres, David, additional, Van Helder, Thomas, additional, Vincent, Jessica, additional, Wang, C. Y., additional, Wang, Michael, additional, Whitlock, Richard, additional, Wittmann, Maria, additional, Xavier, Denis, additional, and Devereaux, P. J., additional

Published
2022
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