Search

Your search keyword '"Ferrannini, Eleuterio"' showing total 436 results
Start Over Author "Ferrannini, Eleuterio"
436 results on '"Ferrannini, Eleuterio"'

216. Disturbance of lymphocyte circulation by Pseudomonas aeruginosa infection in oxazolone-sensitized mice.

Author

Campa, Mario, Ferrannini, Eleuterio, Garzelli, Carlo, Colizzi, Vittorio, and Falcone, Giuseppe

Abstract

Pseudomonas aeruginosa infection depresses contact sensitivity to oxazolone in mice. To test whether an altered lymphocyte circulation plays a role in this depressionCr-labeled lymphocytes from P. aeruginosa-infected and oxazolone-sensitized donors were injected intravenously into infected and sensitized recipients, and the radioactivity uptake of several organs was determine. The controls consisted of normal mice receiving labeled lymphocytes from normal donors. While the radioactivity recovered from the liver, spleen, and mesenteric lymph nodes was similar in the test and the control group, significantly more radioactivity was recovered from the draining lymph nodes of infected and sensitized recipients. The concentration of labeled lymphocytes from sensitized donors in the draining lymph nodes of sensitized recipients was 18% greater than that of the controls but 31% lower than that of infected and sensitized animals receiving cells from infected and sensitized donors. P. aeruginosa infection enhances lymphocyte entrapment within the draining lymph nodes of oxazolone-sensitized mice. [ABSTRACT FROM AUTHOR]

Published
1979
Full Text
View/download PDF

217. Insulin Resistance in Essential Hypertension.

Author

Ferrannini, Eleuterio, Buzzigoli, Giuseppe, Bonadonna, Riccardo, Giorico, Maria Antonietta, Oleggini, Marco, Graziadei, Linda, Pedrinelli, Roberto, Brandi, Luigi, and Bevilacoua, Stefano

Published
1990

232. Sensitivity of insulin secretion to feedback inhibition by hyperinsulinaemia

Author

DeFronzo, Ralph A., Binder, Christian, Wahren, John, Felig, Philip, Ferrannini, Eleuterio, and Faber, Ole K.

Abstract

The ability of insulin to inhibit its own secretion was examined in 15 normal subjects given an intravenous infusion of insulin in a dose of 0.25, 0.50, 1.0, 5.0 or 10.0 mU/kg/min for two hours. Arterial plasma insulin concentration achieved during the infusion segregated into three levels of hyperinsulinaemia: 35 ± 1 (mean ± sem), 87 ± 15 and 828 ± 210 μU/ml. Plasma glucose concentration was kept constant at the basal level by a variable glucose infusion. Fasting C-peptide (0.29 ± 0.02 pmol/ml) fell significantly in all subjects during hyperinsulinaemia and reached a concentration of 0.19 ± 0.03 pmol/ml at 60 min and 0.14 ± 0.03 at 120 min after the start of the insulin infusion. The C-peptide response was not related to the infusion dose nor to the steady state plasma insulin concentration.It is concluded that (a) basal insulin secretion as evaluated from C-peptide measurements is inhibited by small (24 ± 3 μU/ml) physiological elevations in plasma insulin concentration independent of changes in plasma glucose, and (b) supraphysiological or even pharmacological elevations in plasma insulin do not result in a further decrease in endogenous insulin secretion above that achieved with mild hyperinsulinaemia.

Published
1981
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results