300 results on '"Fabrizio Bert"'
Search Results
202. New ways to promote public health: lessons from the international Ice Bucket Challenge
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Fabrizio Bert, Roberta Siliquini, Maria Rosaria Gualano, Giacomo Scaioli, Renata Gili, and Violetta Andriolo
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Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Internationality ,020205 medical informatics ,030508 substance abuse ,Fund Raising ,Health Promotion ,02 engineering and technology ,03 medical and health sciences ,Research Support as Topic ,Political science ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Humans ,Fund raising ,Social media ,business.industry ,Public health ,Amyotrophic Lateral Sclerosis ,Public Health, Environmental and Occupational Health ,General Medicine ,Public relations ,United States ,Health promotion ,Public Health ,0305 other medical science ,business ,Social Media - Published
- 2016
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203. Short-term Intraocular Pressure Spikes Induced by Pneumoperitoneum are Safe for the Optic Nerve in a Healthy Eye
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Luca Grasso, Beatrice Visentin Orthop, Roberta Piccini Orthop, Valentina Battaglino, Andrea Grosso, Giulio Piana Orthop, Piero Ceruti, Enrico Cavallo, Mario Morino, Roberta Siliquini, Marco E. Allaix, Jonathan Crowston, Alberto Bullano, and Fabrizio Bert more...
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medicine.medical_specialty ,Intraocular pressure ,genetic structures ,business.industry ,medicine.disease ,eye diseases ,Term (time) ,03 medical and health sciences ,0302 clinical medicine ,Pneumoperitoneum ,Ophthalmology ,030221 ophthalmology & optometry ,medicine ,Optic nerve ,030211 gastroenterology & hepatology ,sense organs ,business - Abstract
The aim of this study was to determine the effects of the pneumoperitoneum used in colorectal procedures on peripapillary retinal nerve fibre layer (RNFL) thickness. We also analysed the dynamics of ocular anterior segment structures. In this prospective clinical pilot study, 29 patients aged between 45 and 85 years old underwent laparoscopic surgery for selected colorectal diseases. The pneumoperitoneum induced a mean intraocular pressure (IOP) increase of 4 mmHg. Visual acuity, IOP, corneal thickness, angle opening distance (AOD) and the trabeculo-iris space area (TISA) at 500 microns and 750 microns anterior to the scleral spur, RNFL thickness and visual field were measured before and after surgery using Sloan charts, Visante™ optical coherence tomography (OCT) (Zeiss, Oberkochen, Germany), Spectralis® OCT (Heidelberg Engineering, Heidelberg, Germany) and Humphrey Visual Field System® (Zeiss, Oberkochen, Germany). Patients were categorised in two groups to understand the behaviour of IOP: in group one (n=17), patients were in Trendelenburg position; in group two (n=12), patients were in reverse Trendelenburg position. The IOP was measured during surgery by the Icare® Tonometer (Icare, Vantaa, Finland) according to a standardised protocol; the IOP was measured before and after surgery by Goldmann applanation tonometer (Haag-Streit, Koniz, Switzerland). Patients with previous diagnosis of both open or angle-closure glaucoma or anterior segment anomalies were excluded. No statistically significant differences in increase of IOP were found between the two groups (p>0.05); no statistically significant differences in RNFL thickness, visual field, AOD and TISA were found before and after surgery in all patients (p>0.05). In our study we have demonstrated that a mean IOP increase of 4 mmHg over a short period of time is safe for a healthy optic nerve. more...
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- 2018
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204. Association of Histologic Regression in Primary Melanoma With Sentinel Lymph Node Status: A Systematic Review and Meta-analysis
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E. Balagna, Fabrizio Bert, Simona Osella-Abate, Simone Ribero, Giuseppe Macripò, Pietro Quaglino, Anna Sapino, Maria Teresa Fierro, Maria Rosaria Gualano, Martina Sanlorenzo, Roberta Siliquini, and Giacomo Scaioli more...
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medicine.medical_specialty ,Funnel plot ,business.industry ,Sentinel lymph node ,Dermatology ,Publication bias ,Odds ratio ,Cochrane Library ,Surgery ,Internal medicine ,Meta-analysis ,Linear regression ,Medicine ,business ,Rank correlation - Abstract
Importance The prognostic significance of regression in primary melanoma has been debated for many years. There is no consensus regarding the need for sentinel lymph node (SLN) biopsy when regression is present within the primary tumor. Objective To review the evidence that regression may affect SLN status. Data Sources A systematic review was performed by searching in MEDLINE, Scopus, and the Cochrane Library from January 1, 1990, through June 2014. Study Selection All studies that reported an odds ratio (OR) or data on expected and observed cases of SLN positivity and histologic regression were included. Data Extraction and Synthesis Primary random-effects meta-analyses were used to summarize ORs of SLN positivity and histologic regression. Heterogeneity was assessed using the χ 2 test and I 2 statistic. To assess the potential bias of small studies, we used funnel plots, the Begg rank correlation test, and the Egger weighted linear regression test. The methodologic quality of the studies was assessed according to the Strengthening of Reporting of Observational studies in Epidemiology (STROBE) checklist, and 2 different meta-analyses were performed based on those criteria. Main Outcomes and Measures Summary ORs of histologic regression of primary melanoma and SLN status. Results Of the 1509 citations found in the search, 94 articles were reviewed, and 14 studies comprising 10 098 patients were included in the analysis. In the combined 14 studies, patients with regression had a lower likelihood to have SLN positivity (OR, 0.56; 95% CI, 0.41-0.77) than patients without regression. On the basis of study quality, we found that patients with regression enrolled in high-quality studies had a lower likelihood to have SLN positivity (OR, 0.48; 95% CI, 0.32-0.72) compared with results of low-quality studies (OR, 0.73; 95% CI, 0.53-1.00). Examination of the funnel plot did not provide evidence of publication bias. Conclusions and Relevance The results of this analysis showed that the risk of SLN positivity was significantly lower in patients with histologic regression compared with those without. Regression may be used in these cases to make a selection of which patients should be the most appropriate for this procedure. more...
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- 2015
205. What do parents know about antibiotics? A multicenter Italian survey on antibiotics knowledge
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Walter Ricciardi, Francesco Vitale, Italo F. Angelillo, Renata Gili, Gualano, Roberta Siliquini, Silvio Brusaferro, Lamberto Manzoli, G La Torre, E. De Vito, Fabrizio Bert, and Giacomo Scaioli
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medicine.medical_specialty ,medicine.drug_class ,business.industry ,Antibiotics ,Public Health, Environmental and Occupational Health ,medicine ,antibiotics parent ,Intensive care medicine ,business - Published
- 2015
206. Differences existing between USA and Europe in opioids purchase on Internet: An interpretative review
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Stefano Passi, Fabrizio Bert, Roberta Siliquini, Veronica Galis, and Maria Rosaria Gualano
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medicine.medical_specialty ,Internet ,Health (social science) ,business.industry ,Public health ,education ,Scopus ,Medicine (miscellaneous) ,Legislation ,Advertising ,Scientific literature ,Opioids ,Opioid ,Web of knowledge ,medicine ,The Internet ,Purchase ,business ,Inclusion (education) ,health care economics and organizations ,medicine.drug - Abstract
Background: Opioids e-commerce represents an important public health issue. While the literature describes this phenomenon in the USA, the studies about this topic are scarce in Europe. This review aims to describe the state of the art of the online opioids commerce and to explore the factors influencing the opioids e-commerce.Methods: Scientific literature available via four bibliographic databases (PubMed, Cochrane Collaboration, ISI Web of knowledge and Scopus) was screened on June 2012. Keywords used were “Internet and opioids”, “Online and opioids”, “Web and opioids”, “Opioid selling”, “Opioid business”, “Opioid buy”, and “Opioid sale”. After the selection, 31 articles were finally identified as meeting the inclusion criteria.Results: The online market of opioids had experienced a boom thanks to the discount prices, the poor monitoring actions, the quickness and easiness of acquiring of these drugs. Legislation on the sale of drugs online differs among the countries. We found that the opioids... more...
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- 2015
207. Repeated Suicide Attempts in Emergency Room Psychiatric Referrals
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Carla Gramaglia, Debora Marangon, Eugenio Torre, Luigi Mario Castello, Di Marco S, I. Coppola, Fabrizio Bert, A. Venesia, G.C. Avanzi, Roberta Siliquini, C. Delicato, Patrizia Zeppegno, and E. Gattoni more...
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Suicide attempters ,Psychiatry and Mental health ,medicine.medical_specialty ,Suicide behavior ,Suicide attempt ,business.industry ,Alternative medicine ,Medicine ,Omics ,business ,Psychiatry - Abstract
It is widely acknowledged that 16% to 34% of suicide attempters repeat a suicide behavior within 1-2 years after the first, “index”, attempt, and that a previous nonfatal suicide attempt is found in up to 40% of suicide deaths (Scoliers, Portzky, van Heeringen & Audenaert, 2009). Suicide attempt is defined as “a self inflicted, potentially injurious behavior with a nonfatal outcome for which there is evidence (either explicit or implicit) of intent to die; a suicide attempt may result in no injuries, or death” (Silverman, Berman Sanddal & O’carroll, 2007). more...
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- 2015
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208. Antibiotic use: a cross-sectional survey assessing the knowledge, attitudes and practices amongst students of a school of medicine in Italy
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Maria Rosaria Gualano, Renata Gili, Simona Masucci, Giacomo Scaioli, Roberta Siliquini, and Fabrizio Bert
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Genetics and Molecular Biology (all) ,Male ,medicine.medical_specialty ,Health Knowledge, Attitudes, Practice ,Multivariate analysis ,Students, Medical ,Adolescent ,Cross-sectional study ,education ,Drug Resistance ,MEDLINE ,lcsh:Medicine ,Biochemistry ,Young Adult ,Medical ,Health care ,Drug Resistance, Bacterial ,Medicine ,Humans ,Young adult ,Medical prescription ,Students ,lcsh:Science ,Prescription Drug Overuse ,Response rate (survey) ,Practice ,Multidisciplinary ,business.industry ,Health Knowledge ,Medicine (all) ,Public health ,lcsh:R ,Bacterial ,Anti-Bacterial Agents ,Cross-Sectional Studies ,Agricultural and Biological Sciences (all) ,Italy ,Attitudes ,Family medicine ,Female ,Biochemistry, Genetics and Molecular Biology (all) ,lcsh:Q ,business ,Research Article - Abstract
Background Since antibiotic resistance has become a worldwide public health concern and is in part related to physicians’ lack of knowledge, it is essential to focus our attention on healthcare profession students. The present study aims at evaluating the knowledge and attitudes of the School of Medicine’s students towards antibiotic usage and antibiotic resistance. Methods In December 2013, a cross sectional study was conducted amongst medical, dental, nursing and other health care profession students of the School of Medicine at the University of Torino. Students of all the academic years took part in this study. Questionnaires were submitted during regular lectures (only students who attended courses on one specific day were surveyed) and the data collected was analyzed using StataMP11 statistical software. Results Overall, 1,050 students were interviewed. The response rate was 100%. Around 20% of the sample stated that antibiotics are appropriate for viral infections and 15% of the students that they stop taking those drugs when symptoms decrease. Results of the multivariate analyses showed that females were more likely than males to take antibiotics only when prescribed (OR 1.43, 95% CI 1.04–1.98). Interestingly, students with a relative working in a health-related field, as well as those who took at least one course of antibiotics in the last year, had a lower probability of taking those drugs only under prescription (OR = 0.69 95% CI: 0.49–0.97 and OR = 0.38 95% CI: 0.27–0.53, respectively). Conclusion The present paper shows how healthcare profession students do not practice what they know. Since those students will be a behavioral model for citizens and patients, it is important to generate more awareness around this issue throughout their studies. It would be advisable to introduce a specific course and training on antibiotics in the core curriculum of the School of Medicine. more...
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- 2015
209. Socio-Demographic and Clinical Features of Patients Referred to Emergency Room Psychiatric Consultation Between 2006 and 2015. A Comparison Between Migrants and Natives
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G.C. Avanzi, Camilla Vecchi, P. Zeppegno, C. Gramaglia, Fabrizio Bert, Luigi Mario Castello, Eleonora Gambaro, and C. Delicato
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medicine.medical_specialty ,Suicide attempt ,business.industry ,media_common.quotation_subject ,Psychiatric assessment ,Immigration ,Emergency department ,Triage ,Mental health ,Psychiatry and Mental health ,Psychiatric consultation ,Medicine ,business ,Psychiatry ,media_common ,Psychopathology - Abstract
In recent decades, Italy has become a desirable destination for immigrants. It should be noted that the organization of mental health services in Italy strongly relies on outpatient services, while the psychiatric wards usually accommodate patients in acute phases of their disorder. Nonetheless, migrants’ first contact often happen in a psychiatry ward when they are in a severe and acute psychopathological condition. The research was performed in the Emergency Department (ED) of the Maggiore della Carità Hospital, Novara, Italy. We collected data about 3781 consecutive patients, 3247 Italian natives and 421 migrants, assessed in the ER of the Maggiore della Carità Hospital, and referred to psychiatric assessment after ER triage. From 1st January 2006 to 31st December 2007, only data for migrant patients were available. From 1st January 2008 to 31st December 2015, data were available for all consecutive patients assessed in the ER. An experienced psychiatrist assessed patients with a clinical interview, including the assessment of suicidal intent, suicidal behaviors and attempts. The psychiatrist filled in for each patient a data sheet, reporting demographic data and clinical features. The high frequency of substance use disorders was higher in the migrant population than in the native one. The request for psychiatric consultation for self-injury behaviors was more frequent in migrants and also suicide attempts were more common. Nonetheless, being a migrant was not a predictor of suicide attempt in our sample.Several differences were found between migrants and natives in socio-demographic, clinical and treatment variables. Clinical implications will be discussed.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2017
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210. A Descriptive Analysis of Psychological Factors and Childhood Trauma in a Sample of Suicide Attempters
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A. Venesia, Fabrizio Bert, Camilla Vecchi, P. Zeppegno, C. Gramaglia, S. Di Marco, E. Gattoni, and C. Delicato
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Suicide attempters ,medicine.medical_specialty ,Descriptive statistics ,Suicide attempt ,media_common.quotation_subject ,CTQ tree ,Protective factor ,Psychiatry and Mental health ,Sexual abuse ,medicine ,Temperament and Character Inventory ,Psychological resilience ,Psychiatry ,Psychology ,media_common ,Clinical psychology - Abstract
IntroductionChildhood trauma, especially sexual abuse, is associated with an increased risk of suicidal behavior. However, studies also show that according to the stress-vulnerability model, not all individual exposed to this kind of trauma exhibit suicidal behaviors as some protective factors could diminish the aforementioned risk, such as personality factors. Resilience might be one such a protective factor. Furthermore, there has been growing evidence to support the role of impulsive and aggressive behavior in the risk of suicide.ObjectivesTo compare suicide attempters to non-suicide attempters (patients admitted for any other reason) for as far as psychological features and childhood trauma. To verify the role of resilience and coping strategies as protective factor for suicide attempt, mitigating the risk of an individual who has experienced childhood trauma.MethodsWe recruited patients referred to the inpatient and outpatient facilities of psychiatry ward of “Maggiore della Carità” hospital in Novara during the period November 2015–December 2016. We included all patients from 18 to 65 years with a psychiatric disorder that met DSM–5 diagnostic criteria. For the analysis, we divided patients into two subgroups according to the presence/absence of suicidal behaviors. The assessment included: Resilience Scale for Adult (RSA), Brief cope, Rosenberg Self-esteem Scale (RSES), childhood trauma questionnaire (CTQ), temperament and character inventory (TCI).Results and discussionAlthough, the recruitment is still ongoing preliminary results seem to confirm the role of resilience and coping strategies as protective factor mitigating the risk of an individual who has experienced childhood trauma from making a suicide attempt.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2017
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211. Use of self-medication among adolescents: a systematic review and meta-analysis
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Stefano Passi, Veronica Galis, Fabrizio Bert, Maria Rosaria Gualano, Michela Stillo, Roberta Siliquini, and Lamberto Manzoli
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Male ,medicine.medical_specialty ,Pediatrics ,Internationality ,Adolescent ,Population ,MEDLINE ,Socio-culturale ,CHILDREN ,Nonprescription Drugs ,Self Medication ,DRUGS ,Medicine ,Humans ,HEALTH ,POPULATION ,STATEMENT ,KNOWLEDGE ,Sex Distribution ,education ,Adverse effect ,Female ,Observational Studies as Topic ,Public Health, Environmental and Occupational Health ,education.field_of_study ,business.industry ,Public health ,Environmental and Occupational Health ,Meta-analysis ,Family medicine ,Observational study ,Public Health ,business ,Self-medication ,Clinical psychology - Abstract
Background: We performed a systematic review and proportion meta-analysis in order to investigate the prevalence and the adverse effects of the self-medication among the teenagers. Methods: We selected observational studies published from January 1990 until January 2014 that examined the use of self-medication in the adolescents (aged from 13 to 18 years). Keywords used on PubMed, ISI Web of Knowledge and Scopus were ‘self medication’, ‘adolescent*’, ‘self prescription’, ‘over the counter preparations’ and ‘self administration’. Results: Finally, 15 articles met the inclusion criteria, for a total of 143 213 subjects involved. Overall, 50% of adolescents use to take drugs without consulting a physician. Further analyses stratified by number of drugs used demonstrated that in the studies reporting that adolescents use more than one type of drug the prevalence rises up to 63%. Only one study reported the possible adverse effects related to the inappropriate use of drugs, which were experienced by 31.1% of the females and 19.6% of the males. Conclusions: Self-medication use among adolescents is a widespread phenomenon. It would be advisable to give more attention on this public health concern and to promote initiatives, such as mass media campaigns and governmental actions, in order to make the citizens more aware to the risks related to the consumption of drugs without medical consultation. Further studies on adverse effects are urgently needed. more...
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- 2014
212. The reorganization of reception centers for asylum-seekers in Sicily: the validation of the new Italian guidelines for Health Impact Assessment
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S Fulvi, Quinto Tozzi, Vincenzo Restivo, Fabrizio Bert, Salvatore Scondotto, F. Di Stanislao, Gualano, Roberta Siliquini, and E Draghi
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Health services ,Refugee ,Political science ,Agency (sociology) ,Public Health, Environmental and Occupational Health ,Public administration ,Health impact assessment - Abstract
Issue/Problem The situation of humanitarian emergency affecting Sicily and the difficulties highlighted by the media in the reception of migrants have made this topic interesting for carrying out the validation of guidelines for Health Impact Assessment (HIA) introduced in 2013. In particular, the HIA regional working team, in collaboration with the National Agency for Regional Health Services, wanted to investigate the potential health impacts of the reorganization of non-medical support initiatives aimed at … more...
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- 2014
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213. Antibiotic use: knowledge, attitudes and practices among health profession students in Italy
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Giacomo Scaioli, Fabrizio Bert, S Masucci, Gualano, Roberta Siliquini, and Renata Gili
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medicine.medical_specialty ,Antibiotic resistance ,Nursing ,business.industry ,Public health ,Public Health, Environmental and Occupational Health ,Medicine ,Lack of knowledge ,Antibiotic use ,business ,Health professions ,Antibiotic misuse ,World health - Abstract
Background The threat of antibiotic resistance has become a worldwide public health concern, with a substantial economic and clinical burden. In this regard, the World Health Organization estimated that this problem leads, in the European hospitals, to an excess of mortality of 25 000 people every year. Antibiotic misuse, mainly related to physicians’ lack of knowledge and wrong prescribing behaviour, is one of the leading cause of antibiotic resistance. On account of this, it is essential to focus the … more...
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- 2014
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214. General population's knowledge and attitudes about antibiotics: a systematic review and meta-analysis
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Gualano, Roberta Siliquini, Fabrizio Bert, Giacomo Scaioli, and Renata Gili
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education.field_of_study ,medicine.medical_specialty ,Health Knowledge, Attitudes, Practice ,business.industry ,medicine.drug_class ,Pharmacoepidemiology ,Resistance ,Population ,Antibiotics ,Public Health, Environmental and Occupational Health ,Awareness ,Antibiotics, Attitude, Knowledge, Meta-analysis, Pharmacoepidemiology, Resistance ,Anti-Bacterial Agents ,Meta-analysis ,Knowledge ,Cross-Sectional Studies ,Attitude ,Family medicine ,Population Surveillance ,Medicine ,Humans ,education ,business - Abstract
Nowadays, the development of antibiotic resistance represents one of the most important issues of the global public health. The incorrect use of antimicrobial drugs is recognized as one of the leading causes of antibiotic resistance. Therefore, a better understanding of the existing pieces of evidence pertaining knowledge and attitudes about antibiotic and antibiotic resistance in the general population worldwide is advisable.A systematic review and proportion meta-analyses were performed through PubMed and Scopus scientific databases. Cross-sectional studies published from January 2000 to November 2013 and investigating knowledge about antibiotic use and antibiotic resistance were included.Overall, 26 studies have been selected for the systematic review, and 24 of these were included in the meta-analyses. A lack of knowledge about antibiotics was detected. In particular, 33.7% (95%CI 25.2-42.8) of the sample did not know that antibiotics can treat bacterial infections, and 53.9% (95%CI 41.6-66.0) of them did not know that antibiotics are not useful against viruses. Besides, although 59.4% (95%CI 45.7-72.4) of the sample was aware of antibiotic resistance, 26.9% (95%CI 16.6-38.7) of them did not know that misuse of antibiotics can lead to this problem. Finally, 47.1% (95%CI 36.1-58.2) of the subjects stop taking antibiotics when they start feeling better.It would be necessary to strengthen educational initiatives in the community and to push physicians to correctly inform patients in order to make them aware of the importance of a correct behavior concerning antibiotic consumption. more...
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- 2014
215. Anger Expression, Impulsivity And Expressed Emotion: a Comparison Between Patients With Eating Disorder And Schizophrenia
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Fabrizio Bert, P. Prosperini, Carla Gramaglia, Roberta Siliquini, V. Binda, Nunzia Chieppa, A. Lombardi, D. Cenci, C. Rizza, L. Girardi, Patrizia Zeppegno, Eleonora Gambaro, and C. Delicato
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medicine.medical_specialty ,media_common.quotation_subject ,Global Assessment of Functioning ,Hostility ,Anger ,medicine.disease ,Impulsivity ,Psychiatry and Mental health ,Barratt Impulsiveness Scale ,Schizophrenia ,medicine ,Anxiety ,Expressed emotion ,medicine.symptom ,Psychiatry ,Psychology ,Clinical psychology ,media_common - Abstract
IntroductionThe level of express emotion (EE) is a measure of the attitude of close relatives towards a patient and include dimensions as critical comments, hostility and emotional over-involvement. Anger and impulsivity may lead to self-injurious and aggressive behaviours, and often represent an obstacle to treatment.AimsTo compare anger expression, impulsivity and expressed emotion in ED and SCHZ, and to explore the different level of caregivers’ EE in the two groups.MethodsTwenty-five female with ED diagnosis and 25 patients with schizophrenia, were recruited at the Psychiatry Ward and outpatient Service of AOU – Novara, during one year period. Patient's assessment included Global Assessment of Functioning (GAF), Structured Clinical Interview (SCID 1-2), Level of Expressed Emotion Scale (LEE), Paykel scale, State and Trait Anxiety Inventory (STAY 1-2), State-Trait Anger Expression Inventory (STAXY), Barratt Impulsiveness Scale (BIS-11).ResultsLevels of anxiety (both state and trait) are higher in the ED group than in SCHZ. As far as the STAXY is concerned, SCHZ patients score higher than ED ones on control over anger, while general index of anger expression was higher in ED patients. We did not find significant differences in EE between two groups, except for the patient's emotional response of the patient to the disease, which was greater among SCHZ. Both SCHZ and ED patients scored higher on the LEE, Paykel and STAY than their caregivers.ConclusionsSCHZ and ED patients show different patterns of anxiety and anger, but similar profile as far as EE is concerned. Implications for treatment will be discussed.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2016
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216. Smartphones and health promotion: a review of the evidence
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Marika Giacometti, Fabrizio Bert, Roberta Siliquini, and Maria Rosaria Gualano
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medicine.medical_specialty ,Aging ,Patients ,Health Personnel ,Internet privacy ,Web applications ,Medicine (miscellaneous) ,Health Informatics ,Health informatics ,Health Information Management ,Nursing ,medicine ,Humans ,Confidentiality ,Digital divide ,Exercise ,Life Style ,Internet ,Public health ,business.industry ,Project team ,Diet ,Smartphones ,Health promotion ,Computers, Handheld ,M-Health ,Health education ,business ,Mobile device ,Cell Phone ,Information Systems ,Health promotion, M-Health, Public health, Smartphones, Web applications - Abstract
Communication via mobile phones has become an essential tool for health professionals. The latest generation of smartphones is comparable to computers, allowing the development of new applications in health field. This paper aims to describe the use of smartphones by health professionals and patients in the field of health promotion. We conducted a bibliographic search through Pubmed. Then, research results were analyzed critically in order to select the best experiences available. All searches were carried out on November 2012 and were not limited by date. Each item from the initial search was reviewed independently by members of the project team. Initial search returned 472 items with PubMed. After the removal of duplicates, 406 items were reviewed by all the members of the project team and 21 articles were identified as specifically centered on health promotion. In the nutrition field there are applications that allow to count calories and keep a food diary or more specific platforms for people with food allergies, while about physical activity many applications suggest exercises with measurement of sports statistics. Some applications deal with lifestyles suggestions and tips. Finally, some positive experiences are reported in the prevention of falls in elderly and of sexually-transmitted diseases. Smartphones are transforming the ways of communication but the lack of monitoring of contents, the digital divide, the confidentiality of data, the exclusion of the health professional from the management of patient, are the main risks related to their use. more...
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- 2014
217. Next generation of public health professionals: Networks and the EUPHAnxtintegration approach
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Giacomo Scaioli, Arjan van der Star, and Fabrizio Bert
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medicine.medical_specialty ,Career Mobility ,Diffusion of Innovation ,Education, Public Health Professional ,Humans ,Leadership ,Public Health ,Cooperative Behavior ,Professional Competence ,Medicine (all) ,Public Health, Environmental and Occupational Health ,Health administration ,Education ,Environmental health ,Medicine ,Health policy ,HRHIS ,Public Health Professional ,business.industry ,Public health ,Environmental and Occupational Health ,International health ,Public relations ,Young professional ,Health promotion ,Workforce ,Health education ,business - Abstract
In a commentary by Louise Boyle and Sofia Ribeiro, the authors urge on the importance of young professional networks in public health to train them on leadership competencies in a vibrant, international and multidisciplinary atmosphere.1 The Young Forum Gastein initiative is proposed then by the authors as an important tool and network to interact with high-level European health experts. In the past 20 years, giant strides have been made in terms of integration among citizens from different European countries, and new challenges for health sector are continuously arising, such as societal changes, patient-centred care, globalization, more assertive and informed patients.2 These challenges are particularly true considering how the economic crisis and increasing budgetary constraints have put additional pressures on health systems, with consequent reduced health spending in several countries.3 It is important, therefore, that the future public health professionals will be ready to deal with these evolving dares. As promoted in Health 2020 … more...
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- 2014
218. Microbiological contamination of radiological equipment
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D. Minniti, Marco Grosso, Marika Giacometti, Fabrizio Bert, Roberta Siliquini, F. Bistrot, and Maria Rosaria Gualano
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safety ,technical aspects ,Pathology ,medicine.medical_specialty ,Microbiological contamination ,Protective Clothing ,Environmental health ,Surveys and Questionnaires ,occupational/environmental hazards ,Medicine ,Infection control ,Humans ,Radiology, Nuclear Medicine and imaging ,Conventional radiography, equipment, occupational/environmental hazards, infection, safety, technical aspects ,Personal protective equipment ,Conventional radiography ,Cross Infection ,Radiological and Ultrasound Technology ,business.industry ,Public health ,General Medicine ,infection ,Northern italy ,Radiography ,Italy ,Radiological weapon ,Equipment Contamination ,business ,equipment - Abstract
Background: Important changes have occurred in radiological departments (RDs) over the past 30 years. The procedures have become more complex and the number of patients has increased. This scenario could have important implications for public health and infection control but, to date, the scientific literature has dealt little with matters relating to microbiological monitoring in RDs. Purpose: To examine the level of microbiological contamination in the main RDs of Turin, a city in northern Italy, in order to analyze the presence of a possible biological risk. Material and Methods: We analyzed data from 12 RDs. Samples were taken from X-ray tubes, control panels, radiographic cassettes, and imaging plates. We used the French guidelines “Standards NF S 90--351” in order to obtain the threshold values of reference. Through a questionnaire we investigated the use of personal protective equipment by the chiefs of the RDs. Results: We found values out of limits in 41.7% of the X-ray tubes sampled, in 91.7% of the control panels and imaging plates, while only 8% of the radiographic cassettes were contaminated. A total of 58.3% of RDs reported values above the threshold for three out of four samples. In 16.7% of the RDs only one surface presented acceptable values. Conclusion: Healthcare-associated infections are a cogent issue for the RDs, and knowledge of how to prevent them is increasingly required by health professionals. This study is meant to be a first analysis of the issue that highlights the need of further investigations, maybe with a more detailed monitoring through the characterization of the microbial species involved. Moreover, the development of shared and maybe official standards for the evaluation of microbiological contamination in RDs is strongly suggested. more...
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- 2013
219. Norovirus outbreaks on commercial cruise ships: a systematic review and new targets for the public health agenda
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Roberta Siliquini, Stefano Passi, Maria Lucia Specchia, Giacomo Scaioli, Chiara Cadeddu, Cristina Angela Viglianchino, Maria Rosaria Gualano, and Fabrizio Bert
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medicine.medical_specialty ,Epidemiology ,Health, Toxicology and Mutagenesis ,Cruise ,Food Contamination ,Cruises, Infectious diseases, Norovirus, Outbreaks ,Cruises ,medicine.disease_cause ,Disease Outbreaks ,Virology ,Environmental health ,medicine ,Humans ,Ships ,Caliciviridae Infections ,Travel ,business.industry ,Public health ,Norovirus ,Outbreaks ,Outbreak ,United States ,Europe ,Food ,Infectious diseases ,Public Health ,business ,Food Science ,Contaminated food - Abstract
Noroviruses are recognized as the leading cause of human acute viral gastroenteritis worldwide. The rate of outbreaks on cruise ships has grown significantly in recent years. Given the potentially harmful consequences of outbreaks for passengers and crewmembers and the subsequently high costs for cruise companies, disease outbreaks on cruise ships represent a serious public health issue. The aim of our study was to systematically review published studies related to Norovirus outbreaks on commercial cruise ships. We searched the PubMed and Scopus scientific databases. We included eligible studies published from January 1990 to July 2013 that were written in English and described infectious episodes involving at least two passengers and/or crewmembers on a commercial cruise ship. As a result, 15 studies and seven reviews met the inclusion criteria, describing a total of 127 outbreaks. The majority of the cases were reported in Europe and the USA, affecting more...
- Published
- 2013
220. The emerging use of electronic cigarettes: assessing efficacy and adverse effects through a systematic review of published studies
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Fabrizio Bert, Maria Rosaria Gualano, Stefano Passi, Giacomo Scaioli, and Roberta Siliquini
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medicine.medical_specialty ,business.industry ,Public Health, Environmental and Occupational Health ,Alternative medicine ,Medicine ,business ,Adverse effect ,Intensive care medicine - Published
- 2013
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221. The Health Impact Assessment about the introduction of a co-payment duty for health services: a validation of the new guidelines in Southern Italy
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Gualano, Roberta Siliquini, E Draghi, S Fulvi, Fabrizio Bert, and F. Di Stanislao
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Health services ,business.industry ,media_common.quotation_subject ,Environmental health ,Public Health, Environmental and Occupational Health ,Medicine ,business ,Health impact assessment ,Duty ,media_common ,Co-payment - Published
- 2013
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222. Smoking ban policies in Italy and the impact of the so-called Sirchia law: state of the art eight years after
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Stefano Passi, Gualano, Fabrizio Bert, Roberta Siliquini, G La Torre, and Giacomo Scaioli
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Work (electrical) ,State (polity) ,business.industry ,Law ,media_common.quotation_subject ,Public Health, Environmental and Occupational Health ,Medicine ,Christian ministry ,Smoking ban ,business ,health care economics and organizations ,media_common - Abstract
Background Currently, smokers in Italy are around 11 million: of them 43.5% are women. From January 2005 is into force the Law No 3 of January 2003 (the so called Sirchia Law named after the Health Ministry who promoted it) that banned smoking in all indoor public places. The aim of the present work is to describe the state of the art of tobacco habits in Italy, eight years after the law was introduced. Methods Based on a national survey conducted by the National … more...
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- 2013
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223. Norovirus outbreaks on commercial cruise ships: a systematic review and new targets for the public health agenda
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Maria Lucia Specchia, Chiara Cadeddu, Stefano Passi, Fabrizio Bert, Gualano, Roberta Siliquini, and Giacomo Scaioli
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medicine.medical_specialty ,business.industry ,Public health ,Cruise ,Public Health, Environmental and Occupational Health ,Outbreak ,medicine.disease_cause ,Norovirus Outbreaks ,Environmental health ,Public Health Agenda ,Norovirus ,Medicine ,Commercial Cruise Ships ,business ,Settore MED/42 - IGIENE GENERALE E APPLICATA - Published
- 2013
224. Humanisation in the emergency department of an Italian hospital: new features and patient satisfaction
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Bruno Barberis, D. Minniti, Roberta Siliquini, Riccardo Papalia, Marika Giacometti, Fabrizio Bert, Roberto Sacco, E Lovato, and Alberto Piolatto
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,emergency department ,patient satisfaction ,Psychological intervention ,Critical Care and Intensive Care Medicine ,Young Adult ,Sex Factors ,Patient satisfaction ,Surveys and Questionnaires ,Epidemiology ,medicine ,Humans ,In patient ,Humanisation ,Aged ,Quality of Health Care ,business.industry ,Process Assessment, Health Care ,Age Factors ,General Medicine ,Emergency department ,Middle Aged ,emergency department management ,epidemiology ,medicine.disease ,Triage ,Italy ,Emergency Medicine ,Educational Status ,Population study ,Female ,Observational study ,Medical emergency ,Emergency Service, Hospital ,business - Abstract
Objectives The goal of this study was to describe and analyse interventions performed in the emergency department (ED) of an Italian hospital with the aim of humanising the patient care pathway. The actions taken are described and the changes analysed to determine whether they resulted in an increased level of patient satisfaction. Methods An observational study was conducted between October 2010 and March 2011. The data were collected via a telephone questionnaire administered to patients who were admitted to the ED before and after humanisation interventions. The respondents were questioned about their general condition and their level of satisfaction. Results The study population included 297 patients (158 before and 139 after the interventions). The highest overall patient satisfaction after the interventions was highly correlated with the humanisation interventions and not with other factors such as gender, age, educational level or the severity code triage. Specifically, in patients who went to the ED after the changes had been made, there was a greater level of satisfaction regarding comfort in the waiting room, waiting time for the first visit and the privacy experienced during the triage. Conclusion The results demonstrate that the interventions implemented in this study, designed to humanise the ED, improved overall patient satisfaction. Interventions may be taken to reduce the depersonalisation of patients in the emergency room. more...
- Published
- 2013
225. Acute kidney injury after open and endovascular elective repair for infrarenal abdominal aortic aneurysms
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Simone Quaglino, Fabrizio Bert, Gianfranco Varetto, Claudio Castagno, Pietro Rispoli, Gitana Scozzari, and Edoardo Frola
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Male ,medicine.medical_specialty ,Time Factors ,030204 cardiovascular system & hematology ,urologic and male genital diseases ,Blood Vessel Prosthesis Implantation ,03 medical and health sciences ,Aortic aneurysm ,chemistry.chemical_compound ,0302 clinical medicine ,Aneurysm ,Risk Factors ,Odds Ratio ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,Creatinine ,Surgery ,Cardiology and Cardiovascular Medicine ,Chi-Square Distribution ,business.industry ,Incidence ,Endovascular Procedures ,Acute kidney injury ,Odds ratio ,Acute Kidney Injury ,Length of Stay ,medicine.disease ,Abdominal aortic aneurysm ,Logistic Models ,Treatment Outcome ,Italy ,chemistry ,Elective Surgical Procedures ,Multivariate Analysis ,Female ,Complication ,business ,Biomarkers ,Aortic Aneurysm, Abdominal ,Abdominal surgery - Abstract
The aim of this study was to evaluate the incidence of acute kidney injury (AKI) after open and endovascular abdominal aortic aneurysm repair according to the Aneurysm Renal Injury Score classification.We retrospectively evaluated 431 patients undergoing elective open aortic repair (OAR; n = 285) or endovascular repair (n = 146) for infrarenal aortic aneurysm. All data regarding preoperative and postoperative serum creatinine concentrations and postoperative outcomes were assessed. Univariate and multivariate logistic regression models investigated the association between AKI and different risk factors and complications.The incidence of AKI was significantly higher after OAR (26.3% vs 5.5%; P .001). A significant share of patients who experienced AKI were restored to preoperative renal function at discharge (62.5% vs 77.5% in the endovascular and OAR groups, respectively; P = .37). Preoperative serum creatinine concentration was significantly higher in those patients who further developed AKI (1.25 vs 1.04 mg/dL; P .001). At the multivariate analysis, AKI was significantly associated with current smoking (odds ratio [OR], 2.05; 95% confidence interval [CI], 1.19-3.52; P = .01), hypertension (OR, 2.46; 95% CI, 1.21-4.3; P = .01), chronic renal disease (OR, 2.53; 95% CI, 1.42-4.53; P .001), OAR (OR, 7.3; 95% CI, 3.25-16.42; P .001), and arrhythmias (OR, 3.16; 95% CI, 1.09-9.13; P = .03). AKI stage did not affect postoperative outcomes, except for a longer hospital stay in patients in stage 2 and stage 3 compared with stage 1.AKI is a common but often reversible complication, especially after OAR. There is an urgent need of a common classification for AKI after aortic surgery. New diagnostic markers for AKI should be evaluated in large-scale studies to assess their reliability. more...
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- 2016
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226. The Pedagogy of Nature according to Maria Montessori
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Fabrizio Bertolino and Manuela Filippa
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maria montessori ,nature ,childhood ,pedagogy ,education ,Education (General) ,L7-991 - Abstract
The aim of this paper is to examine the multiple concepts of nature expressed in the writings of Maria Montessori, in relation to children’s relationship with nature and salient educational practices. We analyze the multiple meanings that Montessori herself attributed to the term nature”, going on to explore the role of nature in her child pedagogy, as well as her thoughts on caring for nature, in keeping both gardens and animals, and on nature as the ideal setting for sensory education. We ultimately draw together a Montessorian Pedagogy of Nature that underscores the importance of child-nature interaction during the early stages of development. The study was conducted under the PRIN 2019-2021 program, as part of a leading research national project entitled “Maria Montessori from the past to the present”. more...
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- 2021
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227. Correlation between driving-related skill and alcohol use in young-adults from six European countries: the TEN-D by Night Project
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Roberta, Siliquini, Fabrizio, Bert, Francisco, Alonso, Paola, Berchialla, Alessandra, Colombo, Axel, Druart, Marcin, Kedzia, Valeria, Siliquini, Daniel, Vankov, Anita, Villerusa, Lamberto, Manzoli, and A, Villerusa more...
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Adult ,Male ,Automobile Driving ,Adolescent ,Alcohol Drinking ,Poison control ,Occupational safety and health ,Young Adult ,Saliva testing ,Surveys and Questionnaires ,Injury prevention ,Reaction Time ,Medicine ,Humans ,Young adult ,biology ,business.industry ,lcsh:Public aspects of medicine ,Driving simulator ,Public Health, Environmental and Occupational Health ,lcsh:RA1-1270 ,biology.organism_classification ,Europe ,Female ,Cannabis ,Biostatistics ,business ,Demography ,Research Article - Abstract
Background Only few studies with small experimental samples investigated the impact of psychoactive substances on driving performance. We conducted a multicenter international cross-sectional study to evaluate the correlation between alcohol use and driving-related skill as measured by brake reaction time (RT). Methods Before and after the entrance into randomly selected recreational sites from six European countries, all subjects aged 16-35 years, owning a driver license, were asked to compile a structured socio-demographic questionnaire and measure RT (SimuNomad3 driving simulator), breath alcohol concentration (BAC; Drager Alcoltest), and drug use (Oratect III saliva test, only at the exit). Mixed regression modeling was used to evaluate the independent association between RT and alcohol concentration or drug use. Results Before the entrance into the recreational site, 4534 subjects completed all assessments and composed the final sample. Their mean age was 23.1 ± 4.2y; 68.3% were males; 54.7% had BAC > 0 g/L (assumed alcoholics); 7.5% declared illegal drug assumption (mostly cannabis). After the exit, 3019 also completed the second assessment: 71.7% showed BAC > 0 g/L. Controlling for age, gender, educational level, occupation, driver license years, and drug use, BAC was positively associated with RT, achieving significance, however, only when BAC was higher than 0.49 g/L. Significant interaction terms were found between BAC and female gender or drug use, with highest RTs (> 1 sec.) recorded among drug users with BAC > = 1 g/L. Conclusions This field study confirms previous experimental data on the negative impact of alcohol use on driving-related skill, supporting regulations and educational campaigns aimed at discouraging driving after consumption of psychoactive substances. more...
- Published
- 2011
228. Surfing the internet for health information: an italian survey on use and population choices
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E Lovato, Giuseppe La Torre, Michele Ceruti, Gabriele Messina, Roberta Siliquini, Giorgio Liguori, D. Minniti, Stefania Bruno, Elisabetta De Vito, Fabrizio Bert, and Lamberto Manzoli
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,behavior ,cross-sectional ,cross-sectional health ,health ,internet ,Cross-sectional study ,Population ,education ,Sample (statistics) ,Health Informatics ,lcsh:Computer applications to medicine. Medical informatics ,Health informatics ,Cross-sectional Health ,Economica ,Patient Education as Topic ,Cross-sectional ,Environmental health ,medicine ,Humans ,Settore MED/42 - IGIENE GENERALE E APPLICATA ,Aged ,education.field_of_study ,Behavior ,Internet ,Health ,Descriptive statistics ,business.industry ,Public health ,Health Policy ,Middle Aged ,Health indicator ,Computer Science Applications ,Cross-Sectional Studies ,Italy ,lcsh:R858-859.7 ,The Internet ,Female ,Internet health ,business ,Research Article - Abstract
Background Recent international sources have described how the rapid expansion of the Internet has precipitated an increase in its use by the general population to search for medical information. Most studies on e-health use investigated either through the prevalence of such use and the social and income patterns of users in selected populations, or the psychological consequences and satisfaction experienced by patients with particular diseases. Few studies have been carried out in Europe that have tried to identify the behavioral consequences of Internet use for health-related purposes in the general population. The aims of this study are to provide information about the prevalence of Internet use for health-related purposes in Italy according to demographic and socio-cultural features, to investigate the impact of the information found on health-related behaviors and choices and to analyze any differences based on health condition, self-rated health and relationships with health professionals and facilities. Methods A multicenter survey was designed within six representative Italian cities. Data were collected through a validated questionnaire administered in hospital laboratories by physicians. Respondents were questioned about their generic condition, their use of the Internet and their health behaviors and choices related to Internet use. Data were analyzed using descriptive statistics and logistic regression to assess any differences by socio-demographic and health-related variables. Results The sample included 3018 individuals between the ages of 18 and 65 years. Approximately 65% of respondents reported using the Internet, and 57% of them reported using it to search for health-related information. The main reasons for search on the Internet were faster access and a greater amount of information. People using the Internet more for health-related purposes were younger, female and affected by chronic diseases. Conclusions A large number of Internet users search for health information and subsequently modify their health behaviors and relationships with their medical providers. This may suggest a strong public health impact with consequences in all European countries, and it would be prudent to plan educational and prevention programs. However, it could be important to investigate the quality of health-related websites to protect and inform users. more...
- Published
- 2011
229. La Legislazione Italiana in Materia di Impact Assessment: Regioni a Confronto
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Fabrizio, Bert, Michele, Cerruti, Alessandra, Colombo, Emanuela, Lovato, Stefania, Bruno, Giorgio, Liguori, Lamberto, Manzoli, DEL CIMMUTO, Angela, and Roberta, Siliquini
- Published
- 2010
230. Resilience, Coping, Personality Traits, Self-Esteem and Quality of Life in Mood Disorders
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A. Feggi, Roberta Siliquini, P. Zeppegno, Chiara Guerriero, C. Gramaglia, and Fabrizio Bert
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Coping (psychology) ,medicine.medical_specialty ,media_common.quotation_subject ,030501 epidemiology ,medicine.disease ,Mental health ,03 medical and health sciences ,Psychiatry and Mental health ,Mood ,Mood disorders ,Reward dependence ,Self-directedness ,medicine ,Personality ,Psychological resilience ,0305 other medical science ,Psychiatry ,Psychology ,media_common ,Clinical psychology - Abstract
IntroductionResilience is a dynamic, context- and time-specific process that refers to positive adaptation or ability to maintain or regain mental health despite experiencing adversity. Pathways to resilience include biological, psychological, social and dispositional attributes. In mood disorders, resilience may influence frequency of relapse, severity of episodes and response to treatment.AimsTo evaluate resilience as well as personality features, coping abilities, self-esteem and quality of life in a sample of mood disorder patients.MethodsWe recruited mood disorder patients at the Psychiatry institute AOU Maggiore della Carità, Novara. Socio-demographic data were gathered and patients filled in the following self-administered scales: Resilience Scale for Adult (RSA), Brief Cope, Rosenberg Self-Esteem Scale (RSES), Paykel list of stressful events, Temperamental and Character Inventory (TCI), Quality of life (SF-36).ResultsWe collected data from 61 patients. Statistical analysis was performed by calculating the Pearson Correlation Coefficient between the RSA and the other tests. We observed a positive correlation between RSA and coping “Emotion” and coping “Problem”. A negative correlation was found between RSA and coping “Avoidance”. Resilience was also positively related to self-esteem and physical, mental and general health. As far as personality traits are concerned, resilience was positively correlated with Reward dependence, persistence, self transcendence, self directedness and cooperativeness.ConclusionsSince higher resilience levels are related with better physical and mental health, constructive coping and self-esteem, strategies aimed at enhancing resilience could improve treatment and quality of life in patients with mood disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2016
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231. Risk factors for attempted suicide: A prospective study on psychiatric consultations in the emergency room
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A. Venesia, G.C. Avanzi, Fabrizio Bert, Maria Rosaria Gualano, Carla Gramaglia, S. Di Marco, I. Coppola, Eugenio Torre, C. Delicato, Patrizia Zeppegno, E. Gattoni, Roberta Siliquini, Debora Marangon, and Luigi Mario Castello more...
- Subjects
medicine.medical_specialty ,Multivariate analysis ,Data collection ,business.industry ,Psychiatric assessment ,Odds ratio ,Logistic regression ,Confidence interval ,Psychiatry and Mental health ,Statistical significance ,Medicine ,Prospective cohort study ,business ,Psychiatry - Abstract
IntroductionStudies conducted on Italian samples suggested that 70% of self-harms referred to the emergency room (ER) were suicide attempts. Suicide attempts are associated with societal, relationship and individual risk factors, which vary with age and gender, occur in combination, and may change over time. We conducted a previous study on a sample of psychiatric consultations in ER from 2008 to 2011. We observed that female gender, a permanent job and being in the warmer months of the year were risk factors for suicide attempts.AimTo update knowledge about risk factors for attempted suicide analyzing a larger sample of ER psychiatric consultations.MethodsDeterminants of emergency room visits for psychiatric reasons were studied prospectively in a period of 8 years, from 2008 to 2015 at the “Maggiore della Carità” Hospital in Novara. The psychiatric assessment of patients was performed by experienced psychiatrists with a clinical interview. For each patient, a data sheet was filled in order to gather demographic and clinical features. Comparison of qualitative data was performed by means of the Chi2 test while differences between groups for continuous variables were assessed through a t-test. Statistical significance was set at P ≤ 0.05. A multivariate analysis was performed using logistic regression in order to assess the potential predictors of attempted suicide. Results are expressed as odds ratio (OR) with 95% confidence intervals (95% CI).ConclusionsWe have collected data from more than 500 psychiatric consultations for attempted suicide. Data collection and statistical analyses are still ongoing. Implications will be discussed.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2016
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232. In a period of economical crisis who is at risk for attempted suicide?
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A. Venesia, Carla Gramaglia, Roberta Siliquini, G.C. Avanzi, S. Di Marco, Eugenio Torre, Debora Marangon, Patrizia Zeppegno, Fabrizio Bert, I. Coppola, E. Gattoni, Luigi Mario Castello, C. Delicato, and Maria Rosaria Gualano more...
- Subjects
Clinical interview ,medicine.medical_specialty ,media_common.quotation_subject ,Occupational prestige ,Declaration ,010501 environmental sciences ,01 natural sciences ,Clinical Practice ,03 medical and health sciences ,Psychiatry and Mental health ,0302 clinical medicine ,Social integration ,Statistical significance ,Unemployment ,medicine ,In patient ,030212 general & internal medicine ,Psychiatry ,Psychology ,0105 earth and related environmental sciences ,media_common - Abstract
IntroductionAccording to Durkheim's theory, suicide attempts increase during periods of rapid economic changes and decrease again when stability is achieved, due to the social integration in the community guaranteed by occupational status. Since 2009 in Europe, it was observed an increase in the suicide rates, in line with the increase of unemployment. Although unemployment is considered a risk factor for suicide, it was observed a noticeable increase in suicide rates among Italian employed men during the last years, probably related to the specific economic scenario and to emerging difficulties in keeping an income to adequately maintain one's own family standard of living.AimTo study attempted suicides with a specific focus and attention on the current Italian economic scenario.MethodsDeterminants of emergency room visits for psychiatric reasons in patients aged > 16 years were studied prospectively from 2008 to 2015 at the AOU Maggiore della Carità Hospital, Novara, Italy. Each patient was assessed by an experienced psychiatrist with a clinical interview and socio-demographic and clinical features were gathered. Statistical significance was set at P ≤ 0.05.ResultsPreliminary results suggest an increase in suicide attempts according to the rise of the unemployment rate in Novara. Although in absolute figures most attempters are unemployed, it seems that suicide attempts are more frequent in the group of employed subjects, which includes also people under redundancy fund. This subgroup may be considered halfway between employed and unemployed attempters.ConclusionsData collection and statistical analyses are still ongoing. Implications for clinical practice will be discussed.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
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- 2016
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233. Dual diagnosis patients at first admission in an acute psychiatric ward. Trend over a decade
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M. Cavanna, A. Lombardi, Fabrizio Bert, A. Rossi, Patrizia Zeppegno, Roberta Siliquini, and Carla Gramaglia
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Pediatrics ,medicine.medical_specialty ,First admission ,business.industry ,Medical record ,media_common.quotation_subject ,Retrospective cohort study ,medicine.disease ,Substance abuse ,Psychiatry and Mental health ,Medicine ,Dual diagnosis ,Personality ,Medical diagnosis ,business ,Psychiatry ,Psychiatric ward ,media_common - Abstract
IntroductionDual diagnosis (DD) is the coexistence of a Psychiatric Disorder (PD), and Substance Use Disorder (SUD). The increase of DD observed in recent years has caused serious problems to both public and private services organization.AimsOur aim is to assess the prevalence and features (including clinical and sociodemographic ones) of DD over a decade, comparing the period 2003–2004 and 2013–2014.MethodsWe performed a retrospective study retrieving the medical records of DD patients at their first admission to the Psychiatry Ward AOU “Maggiore della Carità”, Novara, Italy. Sociodemographic and clinical features were recorded. The two groups of patients (2003–2004 vs. 2013–2014) were compared.ResultsIn both periods DD patients are usually Italian male, aged 19–40, single. They have usually attended middle school, live with parents, have two or more brothers and/or sisters but no kids. DD patients in 2003–2004 and 2013–2014 showed differences as far as employment and diagnosis are concerned. The first were more frequently employed than the latter: moreover the 2003–2004 patients were more frequently diagnosed with a personality disorder while the 2013–2014 patients had mixed diagnoses. We have found differences in the possible predictors of substance abuse in the two periods, as well.ConclusionsThe identification of changes in the prevalence of first admission DD patients and their clinical and sociodemographic features may help to highlight an evolving pattern of substance use and to identify possible risk factors which may be the target of prevention and treatment approaches.Disclosure of interestThe authors have not supplied their declaration of competing interest. more...
- Published
- 2016
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234. Feline Parvovirus Lethal Outbreak in a Group of Adult Cohabiting Domestic Cats
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Maria Irene Pacini, Mario Forzan, Giovanni Franzo, Claudia Maria Tucciarone, Milena Fornai, Fabrizio Bertelloni, Micaela Sgorbini, Carlo Cantile, and Maurizio Mazzei
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Felis catus ,feline panleukopenia virus ,Protoparvovirus carnivoran1 ,lethal outbreak ,Medicine - Abstract
Feline panleukopenia is a highly contagious and often fatal disease in cats. The virus, known as feline panleukopenia virus (FPV), primarily affects kittens and unvaccinated cats. It is transmitted through contact with infected cats or their bodily fluids, as well as contaminated objects and environments. The diagnosis of FPV infection can be confirmed through a combination of clinical signs, blood tests, and fecal testing. Prevention through vaccination is recommended for all cats. This case report describes an outbreak of feline panleukopenia in a group of unvaccinated domestic cats that resulted in acute mortality. The lesions were evaluated using histopathology, and the specific viral strain was characterized using molecular techniques. The clinical course of the outbreak was peracute, with a hemorrhagic pattern and 100% of lethality. The observed clinical-pathological pattern was unusual; nevertheless, molecular studies did not highlight peculiar genomic features of the parvovirus isolate. The outbreak affected 3 out of 12 cats in a very short time. However, the prompt application of biosecurity measures and vaccination resulted in an effective interruption of virus spread. In conclusion, we could assume that the virus found the ideal conditions to infect and replicate at high titers, resulting in a particularly aggressive outbreak. more...
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- 2023
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235. Colistin Resistance Genes in Broiler Chickens in Tunisia
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Antonietta Di Francesco, Daniela Salvatore, Sonia Sakhria, Fabrizio Bertelloni, Elena Catelli, Salma Ben Yahia, and Aida Tlatli
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antimicrobial resistance ,colistin ,mcr genes ,chicken ,PCR ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Colistin is a polymyxin antibiotic that has been used in veterinary medicine for decades, as a treatment for enterobacterial digestive infections as well as a prophylactic treatment and growth promoter in livestock animals, leading to the emergence and spread of colistin-resistant Gram-negative bacteria and to a great public health concern, considering that colistin is one of the last-resort antibiotics against multidrug-resistant deadly infections in clinical practice. Previous studies performed on livestock animals in Tunisia using culture-dependent methods highlighted the presence of colistin-resistant Gram-negative bacteria. In the present survey, DNA extracted from cloacal swabs from 195 broiler chickens from six farms in Tunisia was tested via molecular methods for the ten mobilized colistin resistance (mcr) genes known so far. Of the 195 animals tested, 81 (41.5%) were mcr-1 positive. All the farms tested were positive, with a prevalence ranging from 13% to 93%. These results confirm the spread of colistin resistance in livestock animals in Tunisia and suggest that the investigation of antibiotic resistance genes by culture-independent methods could be a useful means of conducting epidemiological studies on the spread of antimicrobial resistance. more...
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- 2023
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236. Antimicrobial Resistant Coagulase-Negative Staphylococci Carried by House Flies (Musca domestica) Captured in Swine and Poultry Farms
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Fabrizio Bertelloni, Giulia Cagnoli, Flavio Bresciani, Bruno Scotti, Luca Lazzerini, Marco Marcucci, Giuseppe Colombani, and Valentina Virginia Ebani
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house fly (Musca domestica) ,Staphylococcus spp. ,coagulase-negative staphylococci ,antimicrobial resistance ,Therapeutics. Pharmacology ,RM1-950 - Abstract
House flies (Musca domestica) are very diffuse insects attracted by biological materials. They are abundantly present in farm environments and can frequently come in contact with animals, feed, manure, waste, surfaces, and fomites; consequently, these insects could be contaminated, carry, and disperse several microorganisms. The aim of this work was to evaluate the presence of antimicrobial-resistant staphylococci in house flies collected in poultry and swine farms. Thirty-five traps were placed in twenty-two farms; from each trap, 3 different kinds of samples were tested: attractant material present in the traps, the body surface of house flies and the body content of house flies. Staphylococci were detected in 72.72% of farms, 65.71% of traps and 43.81% of samples. Only coagulase-negative staphylococci (CoNS) were isolated, and 49 isolates were subjected to an antimicrobial susceptibility test. Most of the isolates were resistant to amikacin (65.31%), ampicillin (46.94%), rifampicin (44.90%), tetracycline (40.82%) and cefoxitin (40.82%). Minimum Inhibitory concentration assay allowed to confirm 11/49 (22.45%) staphylococci as methicillin-resistant; 4 of them (36.36%) carried the mecA gene. Furthermore, 53.06% of the isolates were classified as multidrug-resistant (MDR). Higher levels of resistance and multidrug resistance were detected in CoNS isolated from flies collected in poultry farms than in swine farms. Therefore, house flies could carry MDR and methicillin-resistant staphylococci, representing a possible source of infection for animals and humans. more...
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- 2023
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237. House Flies (Musca domestica) from Swine and Poultry Farms Carrying Antimicrobial Resistant Enterobacteriaceae and Salmonella
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Fabrizio Bertelloni, Flavio Bresciani, Giulia Cagnoli, Bruno Scotti, Luca Lazzerini, Marco Marcucci, Giuseppe Colombani, Stefano Bilei, Teresa Bossù, Maria Laura De Marchis, and Valentina Virginia Ebani more...
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house fly (Musca domestica) ,Enterobacteriaceae ,Salmonella spp. ,antimicrobial resistance ,Veterinary medicine ,SF600-1100 - Abstract
The house fly (Musca domestica) is a very common insect, abundantly present in farm settings. These insects are attracted by organic substrates and can easily be contaminated by several pathogenic and nonpathogenic bacteria. The aim of this survey was to evaluate the presence of Salmonella spp. and other Enterobacteriaceae in house flies captured in small-medium size farms, located in Northwest Tuscany, Central Italy, and to evaluate their antimicrobial resistance; furthermore, isolates were tested for extended spectrum β-lactamase and carbapenems resistance, considering the importance these antimicrobials have in human therapy. A total of 35 traps were placed in seven poultry and 15 swine farms; three different kinds of samples were analyzed from each trap, representing attractant substrate, insect body surface, and insect whole bodies. Enterobacteriaceae were isolated from 86.36% of farms, 82.87% of traps, and 60.95% of samples; high levels of resistance were detected for ampicillin (61.25% of resistant isolates) and tetracycline (42.5% of resistant isolates). One extended spectrum β-lactamase producer strain was isolated, carrying the blaTEM-1 gene. Salmonella spp. was detected in 36.36% of farms, 25.71% of traps, and 15.24% of samples. Five different serovars were identified: Kentucky, Kisarawe, London, Napoli, and Rubislaw; some isolates were in R phase. Resistance was detected mainly for ampicillin (31.21%) and tetracycline (31.21%). House flies could represent a serious hazard for biosecurity plans at the farm level, carrying and sharing relevant pathogenic and antimicrobial resistant bacteria. more...
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- 2023
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238. In Vitro Antimicrobial Activity of Thymus vulgaris, Origanum vulgare, Satureja montana and Their Mixture against Clinical Isolates Responsible for Canine Otitis Externa
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Valentina Virginia Ebani, Ylenia Pieracci, Giulia Cagnoli, Fabrizio Bertelloni, Chiara Munafò, Simona Nardoni, Luisa Pistelli, and Francesca Mancianti
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essential oil ,Origanum vulgare ,Satureja montana ,Thymus vulgaris ,antibacterial activity ,antifungal activity ,Veterinary medicine ,SF600-1100 - Abstract
Otitis externa is a frequent inflammation among dogs, mainly caused by bacteria and yeasts that are often resistant to conventional drugs. The aim of the present study was to evaluate the in vitro antibacterial and antifungal activities of commercial essential oils (EOs) from Origanum vulgare, Satureja montana, and Thymus vulgaris, as well as a mixture of these three components, against 47 clinical bacterial strains (Staphylococcus sp., Streptococcus sp., Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Serratia marcescens) and 5 Malassezia pachydermatis strains, previously cultured from the ears of dogs affected by otitis externa. The tested Gram-positive bacteria were sensible to the analysed EOs with MICs ranging from 1.25% (v/v) to v/v); Gram-negative isolates, mainly P. aeruginosa, were less sensitive with MICs from >10% (v/v) to 0.039% (v/v). M. pachydermatis isolates were sensitive to all EOs with MICs from 4.25% (v/v) to 2% (v/v). However, the mixture was active against all bacterial (except one P. aeruginosa strain) and fungal tested isolates. The three EOs and their mixture seem to be an interesting alternative for treating canine otitis externa when conventional antimicrobials are not active. more...
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- 2023
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239. Tetracycline Resistance Genes in Wild Birds from a Wildlife Recovery Centre in Central Italy
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Antonietta Di Francesco, Daniela Salvatore, Fabrizio Bertelloni, and Valentina Virginia Ebani
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wildlife ,free-living birds ,tetracycline resistance genes ,PCR ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Wild animals are less likely to be exposed directly to clinical antimicrobial agents than domestic animals or humans, but they can acquire antimicrobial-resistant bacteria through contact with humans, animals, and the environment. In the present study, 254 dead free-living birds belonging to 23 bird species were examined by PCR for the presence of tetracycline resistance (tet) genes. A fragment of the spleen was collected from each bird carcass. A portion of the intestine was also taken from 73 of the 254 carcasses. Extracted DNA was subjected to PCR amplification targeting the tet(L), tet(M), and tet(X) genes. In total, 114 (45%) of the 254 birds sampled belonging to 17 (74%) of the 23 bird species tested were positive for one or more tet genes. The tet(M) gene showed a higher frequency than the other tested genes, both in the spleen and in the intestine samples. These results confirm the potential role of wild birds as reservoirs, dispersers, or bioindicators of antimicrobial resistance in the environment. more...
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- 2022
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240. Retrospective Molecular Survey on Bacterial and Protozoan Abortive Agents in Roe Deer (Capreolus capreolus) from Central Italy
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Valentina Virginia Ebani, Chiara Trebino, Lisa Guardone, Fabrizio Bertelloni, Giulia Cagnoli, Iolanda Altomonte, Paolo Vignola, Paolo Bongi, and Francesca Mancianti
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Capreolus capreolus ,roe deer ,abortive agents ,Coxiella burnetii ,Toxoplasma gondii ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Bacterial and protozoan agents can determine abortion and other reproductive disorders in domestic ruminants, but data regarding their occurrence in wild ruminants are scanty worldwide, including in Italy. The aim of this retrospective study was to verify the occurrence of the main bacterial and protozoan abortive agents in 72 spleen samples previously collected from roe deer (Capreolus capreolus) living in mountain areas of Central Italy. All samples were collected and submitted to DNA extraction for other investigations. Molecular analyses were carried out on the DNA samples to detect Brucella spp., Chlamydia abortus, Coxiella burnetii, Salmonella enterica, Listeria monocytogenes, Neospora caninum, and Toxoplasma gondii. Three (4.16%) roe deer resulted PCR positive for C. burnetii and one (1.38%) for T. gondii. These findings suggest that roe deer living in the investigated areas do not act as important reservoirs of the searched agents. However, the tested animals lived in a closed area without contact with domestic animals that are usually involved in the epidemiology of the investigated pathogens. Monitoring of wild ruminants is pivotal to verify changes in the epidemiological scenario from a One Health perspective, too. more...
- Published
- 2022
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- View/download PDF
241. Occurrence of Bacterial and Protozoan Pathogens in Red Foxes (Vulpes vulpes) in Central Italy
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Valentina Virginia Ebani, Chiara Trebino, Lisa Guardone, Fabrizio Bertelloni, Giulia Cagnoli, Simona Nardoni, Emily Sel, Emily Wilde, Alessandro Poli, and Francesca Mancianti
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Vulpes vulpes ,red fox ,bacterial pathogens ,protozoan pathogens ,zoonoses ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Most surveys of pathogens in red foxes (Vulpes vulpes) have focused on particular agents. The aim of this study was to verify, with bacteriological and molecular analyses, the occurrence of the main bacterial and protozoan pathogens that are able to infect canids, in red foxes regularly hunted in Central Italy. Spleen, brain, kidney and fecal samples from red foxes were submitted to bacteriological and/or molecular analyses to detect Salmonella spp., Yersinia spp., Listeria monocytogenes, Brucella spp., Ehrlichia canis, Anaplasma phagocytophilum, Coxiella burnetii, Leptospira spp., Neospora caninum, Hepatozoon canis, Babesia spp. and microsporidia. Two (9.1%) strains of Yersinia enterocolitica biotype 1 and 2 (9.1%) of Yersinia frederiksenii were isolated from 22 fecal samples. Among the 22 spleen samples, seven (31.8%) were PCR-positive for H. canis and 3 (13.6%) for Babesia vulpes. Kidneys from two (2.9%) foxes, among 71 tested, were PCR-positive for L. interrogans. Even though the analyses were carried out on a small number of animals, the results suggested that red foxes from the selected geographic area may act as reservoirs of some investigated pathogens. more...
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- 2022
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242. Editorial for the Special Issue: Colistin Resistance—The Need for a One Health Approach
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Fabrizio Bertelloni and Barbara Turchi
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n/a ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Colistin is an “old” antimicrobial belonging to the class of polymyxins, initially discovered in 1947 [...]
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- 2022
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243. Virulence Genes of Pathogenic Escherichia coli in Wild Red Foxes (Vulpes vulpes)
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Fabrizio Bertelloni, Giulia Cagnoli, Fabrizio Biagini, Alessandro Poli, Carlo Bibbiani, and Valentina Virginia Ebani
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Escherichia coli ,virulence genes ,pathotypes ,STEC ,Vulpes vulpes ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Different pathotypes of Escherichia coli can cause severe diseases in animals and humans. Wildlife may contribute to the circulation of pathogenic pathotypes, including enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC), and enterohemorrhagic E. coli (EHEC). This study analyzed 109 DNA samples previously extracted from fecal specimens collected from red foxes (Vulpes vulpes) to detect E. coli virulence genes eaeA, hlyA, stx1, and stx2, that characterize the EPEC, STEC, and EHEC strains. Thirty-one (28.4%) samples were positive for at least one investigated virulence gene: eaeA gene was detected in 21 (19.2%) samples, hlyA in 10 (9.1%), stx1 in 6 (5.5%), and stx2 in 4 (3.6%). Nine DNA samples resulted positive for two or three virulence genes: five (4.6%) samples were positive for eaeA and hlyA genes, two (1.8%) for eaeA and stx1, one (0.9%) for hlyA and stx1, one (0.9%) for eaeA, hlyA and stx2. Red foxes seem to be involved in the epidemiology of these infections and their role could be relevant because they may be source of pathogenic E. coli for other wild animals, as well as domestic animals and humans. more...
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- 2022
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244. Presence of pathogenic Leptospira spp. in the reproductive system and fetuses of wild boars (Sus scrofa) in Italy.
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Giovanni Cilia, Fabrizio Bertelloni, Ivana Piredda, Maria Nicoletta Ponti, Barbara Turchi, Carlo Cantile, Francesca Parisi, Paolo Pinzauti, Andrea Armani, Bruna Palmas, Malgorzata Noworol, Domenico Cerri, and Filippo Fratini more...
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Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
Leptospirosis is a re-emerging and globally spread zoonosis caused by pathogenic genomospecies of Leptospira. Wild boar (Sus scrofa) are an important Leptospira host and are increasing in population all over Europe. The aim of this investigation was to evaluate Leptospira spp. infection in the reproductive systems of wild boar hunted in two Italian regions: Tuscany and Sardinia. From 231 animals, reproductive system tissue samples (testicles, epididymides, uteri) as well as placentas and fetuses were collected. Bacteriological examination and Real-Time PCR were performed to detect pathogenic Leptospira (lipL32 gene). Leptospires were isolated from the testicles and epididymides of one adult and two subadult wild boar. Four isolates from the two subadult males were identified as Leptospira interrogans serogroup Australis by MLST, whereas Leptospira kirschneri serogroup Grippotyphosa was identified from the adult testicles and epididymis. Using Real-Time PCR, 70 samples were positive: 22 testicles (23.16%) and 22 epididymides (23.16%), 10 uteri (7.35%), 3 placentas (6.66%), and 13 fetuses (28.88%). Amplification of the rrs2 gene identified L. interrogans and L. kirschneri species. The results from this investigation confirmed that wild boar represent a potential source of pathogenic Leptospira spp. Isolation of Leptospira serogroups Australis and Grippotyphosa from the male reproductive system and the positive Real-Time PCR results from both male and female samples could suggest venereal transmission, as already demonstrated in pigs. Furthermore, placentas and fetuses were positive for the lipL32 target, and this finding may be related to a possible vertical transmission of pathogenic Leptospira. more...
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- 2020
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245. Occurrence of Escherichia coli virulence genes in feces of wild birds from Central Italy
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Fabrizio Bertelloni, Errica Lunardo, Guido Rocchigiani, Renato Ceccherelli, and Valentina Viginia Ebani
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wild birds ,enteropathogenic escherichia coli ,enterohemorrhagic escherichia coli ,shiga-toxins producing escherichia ,coli ,Arctic medicine. Tropical medicine ,RC955-962 - Abstract
Objective: To investigate the potential role of wild birds as fecal spreaders of enteropathogenic, enterohemorrhagic and Shiga-toxins producing Escherichia coli (E. coli), enteropathogenic E. coli, enterohemorrhagic E. coli and Shiga toxin-producing E. coli strains. Methods: Fecal samples collected from 121 wild birds of different orders and species were submitted to molecular analyses. In particular, eaeA encoding intimin, hlyA encoding for hemolysin, stx1 and stx2 genes encoding Shiga-toxins 1 and 2, respectively, were investigated. Results: Overall, 21(17.35%) fecal samples resulted positive for at least one of the investigated genes. In detail, 12(9.91%) samples were positive for eaeA, 10(8.26%) for stx1, 4(3.31%) for hylA and 1(0.83%) for stx2. An owl (Athene noctua) positive for the four investigated genes suggesting that it harbored a STEC strain. However, virulence genes characterizing EPEC, and EHEC strains were mainly found among seagulls, waterfowl and feral pigeons. Conclusions: Seagulls, waterfowl and feral pigeons, which frequently reach and contaminate rural, urban and peri-urban areas with their droppings, may be important sources of E. coli infection for other animals and humans. more...
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- 2019
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246. Antimicrobial-Resistant Enterococcus spp. in Wild Avifauna from Central Italy
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Giulia Cagnoli, Fabrizio Bertelloni, Paolo Interrante, Renato Ceccherelli, Margherita Marzoni, and Valentina Virginia Ebani
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Enterococcus spp. ,antimicrobial resistance ,wild birds ,feces ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Bacteria of the genus Enterococcus are opportunistic pathogens, part of the normal intestinal microflora of animals, able to acquire and transfer antimicrobial resistance genes. The aim of this study was to evaluate the possible role of wild avifauna as a source of antimicrobial-resistant enterococci. To assess this purpose, 103 Enterococcus spp. strains were isolated from the feces of wild birds of different species; they were tested for antimicrobial resistance against 21 molecules, vancomycin resistance, and high-level aminoglycosides resistance (HLAR). Furthermore, genes responsible for vancomycin, tetracycline, and HLAR were searched. E. faecium was the most frequently detected species (60.20% of isolates), followed by E. faecalis (34.95% of isolates). Overall, 99.02% of the isolated enterococci were classified as multidrug-resistant, with 19.41% extensively drug-resistant, and 2.91% possible pan drug-resistant strains. Most of the isolates were susceptible to amoxicillin/clavulanic acid (77.67%) and ampicillin (75.73%), with only 5.83% of isolates showing an ampicillin MIC ≥ 64 mg/L. HLAR was detected in 35.92% of isolates, mainly associated with the genes ant(6)-Ia and aac(6′)-Ie-aph(2″)-Ia. Few strains (4.85%) were resistant to vancomycin, and the genes vanA and vanB were not detected. A percentage of 54.37% of isolates showed resistance to tetracycline; tet(M) was the most frequently detected gene in these strains. Wild birds may contribute to the spreading of antimicrobial-resistant enterococci, which can affect other animals and humans. Constant monitoring is essential to face up to the evolving antimicrobial resistance issue, and monitoring programs should include wild avifauna, too. more...
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- 2022
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247. Low Level of Colistin Resistance and mcr Genes Presence in Salmonella spp.: Evaluation of Isolates Collected between 2000 and 2020 from Animals and Environment
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Fabrizio Bertelloni, Giulia Cagnoli, Barbara Turchi, and Valentina Virginia Ebani
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Salmonella ,colistin resistance ,mcr ,animals ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Salmonellosis is one of the most important zoonoses in Europe and the world. Human infection may evolve in severe clinical diseases, with the need for hospitalization and antimicrobial treatment. Colistin is now considered an important antimicrobial to treat infections from multidrug- resistant Gram-negative bacteria, but the spreading of mobile colistin-resistance (mcr) genes has limited this option. We aimed to evaluate colistin minimum inhibitory concentration and the presence of mcr (mcr-1 to mcr-9) genes in 236 Salmonella isolates previously collected from different animals and the environment between 2000 and 2020. Overall, 17.79% of isolates were resistant to colistin; no differences were observed in relation to years of isolation (2000–2005, 2009–2014, and 2015–2020), Salmonella enterica subspecies (enterica, salamae, diarizonae, and houtenae), origin of samples (domestic animals, wildlife, and environment), or animal category (birds, mammals, and reptiles); only recently isolated strains from houseflies showed the most resistance. Few isolates (5.93%) scored positive for mcr genes, in particular for mcr-1, mcr-2, mcr-4, mcr-6, and mcr-8; furthermore, only 2.54% of isolates were mcr-positive and colistin-resistant. Detected resistance to colistin was equally distributed among all examined Salmonella isolates and not always related to the presence of mcr genes. more...
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- 2022
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248. Molecular Detection of Avipoxvirus in Wild Birds in Central Italy
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Fabrizio Bertelloni, Renato Ceccherelli, Margherita Marzoni, Alessandro Poli, and Valentina Virginia Ebani
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Avipoxvirus ,wild birds ,aquatic birds ,Anseriformes ,PCR ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Avipoxviruses (APVs) are important pathogens of both domestic and wild birds. The associated disease is characterized by skin proliferative lesions in the cutaneous form or by lesions of the first digestive and respiratory tracts in the diphtheritic form. Previous studies investigated these infections in symptomatic wild birds worldwide, including Italy, but data about the circulation of APVs in healthy avian wildlife are not available. The present study tested spleen samples from 300 wild birds without typical lesions to detect Avipoxvirus DNA. Overall, 43.33% of the samples scored positive. Aquatic birds were more frequently infected (55.42%) than other animals (26.40%), and in Anseriformes, high positivity was found (52.87%). The obtained results suggest that wild birds could be asymptomatic carriers of Avipoxviruses, opening new possible epidemiological scenarios. more...
- Published
- 2022
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249. Tear Production, Intraocular Pressure, Ultrasound Biometric Features and Conjunctival Flora Identification in Clinically Normal Eyes of Two Italian Breeds of Chicken (Gallus gallus domesticus)
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Samanta Nardi, Federico Puccini Leoni, Viola Monticelli, Valentina Virginia Ebani, Fabrizio Bertelloni, Margherita Marzoni, Francesca Mancianti, Simonetta Citi, and Giovanni Barsotti
- Subjects
tear production ,intraocular pressure ,ultrasound biometric features ,conjunctival microflora ,chicken ,Gallus gallus domesticus ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Given the abundance of chickens in Italy, it is important for veterinarians to know the normal state of chickens’ eyes in order to identify any ophthalmic pathological changes. The aim of this study was to determine the normal values of select ocular parameters and to evaluate conjunctival microflora in two Italian chicken breeds. Sixty-six healthy chickens underwent a complete ophthalmic examination, which included a phenol red thread test (PRTT) for the evaluation of tear production and the assessment of intraocular pressure by rebound tonometry. B-mode ultrasound biometric measurements and conjunctival microflora identification were also performed in twenty-seven chickens. Mean PRTT was 23.77 ± 2.99 mm/15 s in the Livorno breed and 19.95 ± 2.81 mm/15 s in the Siciliana breed. Mean intraocular pressure was 14.3 ± 1.17 mmHg in the Livorno breed and 14.06 ± 1.15 mmHg in the Siciliana breed. Reference ranges for morphometric parameters were reported in the two breeds. Twenty-three chickens (85.18%) were bacteriologically positive. Chlamydia spp. antigen was detected in 14.81% of chickens. No positive cultures were obtained for fungi. Normal reference range values for selected ophthalmic parameters were obtained in clinically healthy chickens, which could facilitate accurate diagnosis and better management of ophthalmic diseases in these animals. more...
- Published
- 2021
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250. Antimicrobial Activity and Composition of Five Rosmarinus (Now Salvia spp. and Varieties) Essential Oils
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Ylenia Pieracci, Daniela Ciccarelli, Silvia Giovanelli, Luisa Pistelli, Guido Flamini, Claudio Cervelli, Francesca Mancianti, Simona Nardoni, Fabrizio Bertelloni, and Valentina Virginia Ebani
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Rosmarinus officinalis ,Rosmarinus eriocalyx ,‘Boule’ ,‘Vicomte de Noailles’ ,‘Gorizia’ ,‘Joyce de Baggio’ ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Salvia rosmarinus Spenn. and Salvia jordanii J.B.Walker are aromatic evergreen shrubs belonging to the Lamiaceae family. Their aerial parts have been used since ancient times as natural preservatives. The present study reported the investigation of the chemical profile and the extraction yield of the essential oils (EOs) obtained from the dried aerial parts of four cultivars of Salvia rosmarinus (‘Boule’; ‘Vicomte de Noailles’; ‘Gorizia’; ‘Joyce de Baggio’) and the species S. jordanii, together with their antibacterial and antifungal activities. The phytochemical investigation evidenced a predominance of oxygenated monoterpenes in all the samples (57.5–77.1%), except in ‘Boule’, in which the hydrocarbon form prevailed (50.2%). Principal Component Analysis (PCA) of the matrix taxa × compounds showed that nine compounds have a significant discriminating function between the samples. ‘Vicomte de Noailles’ was characterized by high amounts of camphor and 14-hydroxy-9-epi-(E)-caryophyllene, while ‘Gorizia’ and Jord differed in their predominance of camphene, borneol, bornyl acetate, and α-humulene. Lastly, ‘Boule’ and ‘Joyce de Baggio’ segregated separately and were characterized by high amounts of α-pinene, myrcene, and verbenone. The selected EOs presented a moderate antibacterial activity on the tested bacterial strains and resulted not active on the tested yeast species. more...
- Published
- 2021
- Full Text
- View/download PDF
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