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205. The ethics of AI business practices: a review of 47 AI ethics guidelines

Author

Attard-Frost, Blair, De los Ríos, Andrés, and Walters, Deneille R.

Abstract

Many AI ethics guidelines have recently been published that center the fairness, accountability, sustainability, and transparency of algorithmic decision-making. Relatively few guidelines center the ethics of the business practices and political economies in which AI systems are situated. We present the findings of a semi-systematic literature review and thematic analysis aimed at determining the extent to which the ethics of AI business practices are considered in a large sample of guidelines. Our review reveals that the political and economic implications of AI business practices are greatly underrepresented in AI ethics guidelines. In its current state, AI ethics guidelines focus disproportionately on issues of algorithmic decision-making, while the fairness, accountability, sustainability, and transparency of the business decision-making contexts in which AI systems are situated remain seriously undermined by competitive and speculative norms, ethics washing, corporate secrecy, and other harmful business practices. We discuss these challenges, and we suggest that the ontological and disciplinary scope of future AI ethics guidelines should be expanded to better contend with them.

Published
2022
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208. Anatomy of soft body of Pugilina cochlidium (Linnaeus, 1758) and P. erecta (Vermeij & Raben, 2009) (Neogastropoda: Melongenidae) from Thondi Coast-Palk Bay in Tamil Nadu, India.

Author

De los Ríos-Escalante, P., Ragunathan, C., Kanagu, L., and Stella, C.

Subjects
NEOGASTROPODA, ANATOMY, GENITALIA, NERVOUS system, DIGESTIVE organs, FEMALE reproductive organs, PENIS
Abstract

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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209. La justicia de paz y las transformaciones en el gobierno de la ciudad (Rosario, 1852-1872).

Author

De los Ríos, Evangelina

Subjects
JUDICIAL process, LEGAL judgments, CONSTRUCTION industry, BUILDING permits, JUDGES
Abstract

Copyright of Revista de Indias is the property of Consejo Superior de Investigaciones Cientificas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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211. El préstamo hipotecario y el mercado del crédito en la Unión Europea

Author

de la Sierra Flores Doña, Mª, Gil, José Tomás Raga, Rodríguez, Carmen Callejo, Lanzarot, Ana Isabel Berrocal, Carrasco, Marta Blanco, Ruíz, Emilio Díaz, de los Ríos Flores, Miguel Díez, Gutiérrez, Cristóbal Espín, Morales, Antonio Fernández, de la Sierra Flores Doña, María, Naharro, Mónica Fuentes, de la Bárcena Garcimartín, Fernando Marín, Rosado, Javier Martínez, Toledano, María Cruz Mayorga, Pérez, Ana Felícitas Muñoz, Sánchez, María Rosa Tapia, Muiña, Tania Vázquez, de la Sierra Flores Doña, Mª, Gil, José Tomás Raga, Rodríguez, Carmen Callejo, Lanzarot, Ana Isabel Berrocal, Carrasco, Marta Blanco, Ruíz, Emilio Díaz, de los Ríos Flores, Miguel Díez, Gutiérrez, Cristóbal Espín, Morales, Antonio Fernández, de la Sierra Flores Doña, María, Naharro, Mónica Fuentes, de la Bárcena Garcimartín, Fernando Marín, Rosado, Javier Martínez, Toledano, María Cruz Mayorga, Pérez, Ana Felícitas Muñoz, Sánchez, María Rosa Tapia, and Muiña, Tania Vázquez

Published
2016
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212. René Zavaleta Mercado : Ensayos, testimonios y re-visiones

Author

Ibargüen, Maya Aguiluz, de los Ríos Méndez, Norma, Mercado, René Zavaleta, Feijóo, José Valenzuela, Nigrini, Giovanna Valenti, Mealla, Luis Tapia, Sala, Lucía, Contardo, Eduardo Ruiz, Morales, Hugo Rodas, Anyul, Martín Puchet, Oliver, Lucio, Pacheco, Mario Miranda, Mansilla, Jorge, Q., Mauricio Gil, Bórquez, Elvira Concheiro, Roa, Jorge Cadena, Bartra, Roger, J., Luis H. Antezana, Ibargüen, Maya Aguiluz, de los Ríos Méndez, Norma, Mercado, René Zavaleta, Feijóo, José Valenzuela, Nigrini, Giovanna Valenti, Mealla, Luis Tapia, Sala, Lucía, Contardo, Eduardo Ruiz, Morales, Hugo Rodas, Anyul, Martín Puchet, Oliver, Lucio, Pacheco, Mario Miranda, Mansilla, Jorge, Q., Mauricio Gil, Bórquez, Elvira Concheiro, Roa, Jorge Cadena, Bartra, Roger, and J., Luis H. Antezana

Published
2006

213. Spatial distribution and abundance of non-native barnacles of the genus AmphibalanusPitombo, 2004 (Cirripedia: Balanidae) in southern Iraq

Author

Naser, Murtada D, Yasser, Amaal Gh, De los Ríos-Escalante, Patricio R, and Essl, Franz

Abstract

Invasions of non-native species have been occurring across the globe, mostly due to human activities or climate change. Although most introduced species fail to expand or have slight impact on their new ecosystems, the large number of true invasive species has led to serious economic and ecological problems. Knowledge of the fundamental drivers shaping the current distribution and abundance of invasive species of barnacles of the genus AmphibalanusPitombo, 2004in Iraq are still poorly understood. We collected samples of barnacles from 21 sites from the lower reaches of the Shatt Al-Arab with salinities of 20–24 ppt to the upper part of the Shatt Al-Arab, and northwest to the Al-Hammar marshes and the Euphrates River with salinities of 0.9–2.8 ppt. Amphibalanus amphitrite(Darwin, 1854) was widely distributed, occurring at most sites. With the exception of a few sites close to the mouth of the Shatt Al-Arab, A. improvisus(Darwin, 1854) was restricted to sites with salinities of 22–37 ppt. Amphibalanus subalbidus(Henry, 1973) had an oligohaline distribution, occurring in moderately saline water. Redundancy analysis (RDA) revealed that the spatial distribution and abundance of all three species were influenced by salinity and temperature. Overall, our results confirm the importance of mapping the spatial distribution and abundance of invasive species in order to assess and manage the risks these species pose to native ecosystems.

Published
2024
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214. Ciudades inteligentes, más que tecnología.

Author

Guerra de los Ríos, Bibiana María

Abstract

Copyright of Revista Cultura Económica is the property of Pontificia Universidad Catolica Argentina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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215. Radular morphology by using SEM in Pugilina cochlidium (Gastropoda: Melongenidae) populations, from Thondi coast-Palk Bay in Tamil Nadu-South East coast of India.

Author

De los Ríos, Patricio, Kanagu, Laksmanan, Lathasumathi, Chokkalingam, and Stella, Chelladurai

Subjects
BICUSPIDS, MORPHOLOGY, DIAGNOSIS, TEETH, BAYS, GASTROPODA
Abstract

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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218. Antología del pensamiento crítico mexicano contemporáneo

Author

Bórquez, Elvira Concheiro, Jiménez, Alejandro Fernando González, Santiago, Aldo A. Guevara, Reyna, Jaime Ortega, Chávez, Víctor Hugo Pacheco, Semo, Enrique, Gilly, Adolfo, Casanova, Pablo González, Batalla, Guillermo Bonfil, Pereyra, Carlos, Monsiváis, Carlos, Tibol, Raquel, Castellanos, Rosario, Rojo, Enrique González, Ramírez, Ramón, Revueltas, José, Montemayor, Carlos, Poniatowska, Elena, de los Ríos, Marcela Lagarde y, Miranda, José Porfirio, de los Altos de Chiapas, Mujeres Zapatistas, Esther, Comandanta, Vázquez, Adolfo Sánchez, Echeverría, Bolívar, Kanoussi, Dora, Dussel, Enrique, Bórquez, Elvira Concheiro, Jiménez, Alejandro Fernando González, Santiago, Aldo A. Guevara, Reyna, Jaime Ortega, Chávez, Víctor Hugo Pacheco, Semo, Enrique, Gilly, Adolfo, Casanova, Pablo González, Batalla, Guillermo Bonfil, Pereyra, Carlos, Monsiváis, Carlos, Tibol, Raquel, Castellanos, Rosario, Rojo, Enrique González, Ramírez, Ramón, Revueltas, José, Montemayor, Carlos, Poniatowska, Elena, de los Ríos, Marcela Lagarde y, Miranda, José Porfirio, de los Altos de Chiapas, Mujeres Zapatistas, Esther, Comandanta, Vázquez, Adolfo Sánchez, Echeverría, Bolívar, Kanoussi, Dora, and Dussel, Enrique

Published
2015
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219. Sacrocolpopexia laparoscópica para el tratamiento del prolapso apical: resultados y seguimiento a largo plazo

Author

Ricardo Vásquez R, Carolina Cifuentes P, José F De los Ríos P, Luis Jiménez Z, Luis Almanza P., Gustavo Calle G, Juan Castañeda R, Claudia López R, and Adriana Arango M

Subjects
Sacrocolpopexy, prolapso de órganos pélvicos, pelvic organ prolapsed, laparoscopy, Sacrocolpopexia, prolapso de cúpula vaginal, Obstetrics and Gynecology, laparoscopia, vaginal vault prolapse
Abstract

Objetivos: Evaluar los resultados subjetivos, anatómicos y funcionales a largo plazo de las pacientes sometidas a sacrocolpopexia laparoscópica para manejo de prolapso apical. Métodos: Estudio observacional con pacientes a quienes se les hizo sacrocolpopexia laparoscópica entre febrero de 2006 y diciembre de 2012, en tres centros. El nivel de soporte del piso pélvico se midió mediante la escala de cuantificación del prolapso de órganos pélvicos (POP-Q). Los resultados funcionales se evaluaron mediante un cuestionario de síntomas intestinales, urinarios, sexuales y de molestias físicas. También se estimó la satisfacción global de las pacientes con una escala de uno a diez. Resultados: Se realizó sacrocolpopexia laparoscópica a 68 pacientes, pero el seguimiento fue posible sólo en 24. Ninguna paciente tuvo prolapso apical postoperatorio. El punto C medio del POP-Q fue -6,8 cm. Se observó mejoría importante con respecto a los síntomas subjetivos de prolapso con reducciones significativas en las puntuaciones del cuestionario en el seguimiento postoperatorio. La satisfacción fue en promedio de 9,1. La incontinencia urinaria preoperatoria se resolvió en el 35 % de las que la reportaron, sin necesidad de cirugía de continencia concomitante. No hubo complicaciones a corto plazo. A largo plazo hubo una hernia incisional en el sitio del trocar y una obstrucción intestinal por la malla. Conclusión: La sacrocolpopexia laparoscópica es un tratamiento quirúrgico seguro y eficaz para el prolapso apical post-histerectomía. Proporciona un excelente soporte apical y buen nivel de satisfacción, con una mejoría general de los síntomas de prolapso. Objective: To evaluate the long-term subjective, anatomical and functional outcomes after laparoscopic sacrocolpopexy for apical prolapse. Methods: An observational study of women undergoing laparoscopic sacrocolpopexy between February 2006 and December 2012 was undertaken, at three centers. Pelvic organ support was assessed objectively using the pelvic organ prolapse quantification scale (POP-Q). Functional outcomes were assessed using a questionnaire of bowel, urinary, sexual and physical discomfort symptoms postoperatively. Also was assessed the overall satisfaction of surgery with a scale of one to ten. Results: During the period of the study, sacrocolpopexy was done in 68 patients, but follow-up was possible only in 24. At a mean follow up of 34 months, all 24 women had stage 0 vault support with point C of the POP-Q score averaging -6.8 cm. Subjective improvements in prolapse symptoms were observed with significant reductions in the questionnaire scores. The satisfaction measured with visual scale averaged 9.1. Fifteen women reported stress urinary incontinence before sacrocolpopexy, and it was resolved in 35% without concomitant continence surgery. New onset incontinence was reported in two women. There were no intraoperative and perioperative complications. The long term complications were an incisional hernia on the trocar port site and bowel obstruction caused by the mesh that needed intestinal resection. Conclusions: Laparoscopic sacrocolpopexy is a safe and effective surgical treatment for post-hysterectomy apical prolapse. It provides excellent apical support and good level of satisfaction, with overall improvement in prolapse symptoms.

Published
2013
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220. Histerectomía laparoscópica total: manejo ambulatorio. Experiencia Clínica del Prado, Medellín, Colombia

Author

Adriana Arango M, Ana M Mejía B, Henry Muñoz S, Germán García S, José F De los Ríos P, Ricardo Vásquez R, Juan Castañeda R, Eduardo Serna A, Álvaro J Escobar F, and Gustavo Calle G

Subjects
Obstetrics and Gynecology
Abstract

Objetivo: Describir los resultados de la histerectomia laparoscopica total ambulatoria. Metodo: Se analizan 297 pacientes sometidas a histerectomia laparoscopica total y que fueron dadas de alta luego de la recuperacion anestesica, entre mayo de 2007 y marzo de 2008. Se requeria una puntuacion de menos de 5 en la escala visual analoga del dolor para el alta. Resultados: El promedio de edad fue de 42 anos, el tiempo quirurgico de 79,1 minutos, el sangrado estimado fue de 37,1 ml, el tiempo promedio de estancia total fue de 9,4 horas con un tiempo promedio de estancia postoperatoria de 5,4 horas. La tasa de complicaciones postoperatorias fue de 11,8% y la de readmisiones del 3,3%. El promedio de Escala Visual Analoga del dolor para la primera noche fue de 4,2 puntos. El 6% de las pacientes presentaron vomitos en su domicilio. El 99% de las pacientes recomendarian este tipo de manejo. Conclusiones: El manejo ambulatorio despues de histerectomia laparoscopica total es posible, seguro y bien evaluado por las pacientes. Este manejo no conlleva un mayor riesgo de complicaciones y la tasa de readmisiones es baja.

Published
2011
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221. Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation

Author

Calzaferri, Francesco, Narros-Fernández, Paloma, de Pascual, Ricardo, de Diego, Antonio M.G., Nicke, Annette, Egea, Javier, García, Antonio G., and de los Ríos, Cristóbal

Abstract

The ATP-gated P2X7 purinergic receptor (P2X7) is involved in the pathogenesis of many neurodegenerative diseases (NDDs). Several P2X7 antagonists have been developed, though none of them reached clinical trials for this indication. In this work, we designed and synthesized novel blood–brain barrier (BBB)-permeable derivatives as potential P2X7 antagonists. They comprise purine or xanthine cores linked to an aryl group through different short spacers. Compounds were tested in YO-PRO-1 uptake assays and intracellular calcium dynamics in a human P2X7-expressing HEK293 cell line, two-electrode voltage-clamp recordings in Xenopus laevisoocytes, and in interleukin 1β release assays in mouse peritoneal macrophages. BBB permeability was assessed by parallel artificial membrane permeability assays and P-glycoprotein ATPase activity. Dichloroarylpurinylethanones featured a certain P2X7 blockade, being compound 6(2-(6-chloro-9H-purin-9-yl)-1-(2,4-dichlorophenyl)ethan-1-one), named ITH15004, the most potent, selective, and BBB-permeable antagonist. Compound 6can be considered as a first non-nucleotide purine hit for future drug optimizations.

Published
2021
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222. Neurosarcoidosis: análisis de una serie de 20 pacientes

Author

Carazo Barrios, Lina, Abarca Costalago, Manuel, Hidalgo Conde, Ana, Arnedo Díez de los Ríos, Rocío, García Portales, Rosa, and García Martín, Guillermina

Abstract

La neurosarcoidosis es una rara complicación de la sarcoidosis. Existen series cortas de pacientes con esta afectación. En España son prácticamente inexistentes. Planteamos realizar un estudio retrospectivo sobre neurosarcoidosis en el Hospital Virgen de la Victoria a lo largo de 10 años.

Published
2020
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223. C-reactive protein at ICU admission as a marker of early graft dysfunction after liver transplant. A prospective, single-center cohort study

Author

Seller-Pérez, G., Barrueco-Francioni, J.E., Lozano-Sáez, R., Arrebola-Ramírez, M.M., Diez-de-los-Ríos, M.J., Quesada-García, G., and Herrera-Gutiérrez, M.E.

Abstract

To explore the behavior of C-reactive protein (CRP) after orthotopic liver transplantation (OLT) during the first postoperative days, and its usefulness as a marker of severe early allograft dysfunction (EAD).

Published
2020
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224. First report of inventory and role of macroinvertebrates and fish in Cautín river (38° S, Araucania region Chile).

Author

Vega, R., De los Ríos, P., Encina, F., Norambuena, J. A., Barile, J., and Mardones, A.

Subjects
AMPHIPODA, SNOWMELT, FRESHWATER crabs, INTRODUCED fishes, ENDEMIC fishes, RIVERS, SALMONIDAE
Abstract

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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225. Age and growth of two populations of Pugilina cochlidium (Gastropoda: Melongenidae), from Thondi coast-Palk Bay in Tamil Nadu-South East coast of India.

Author

De los Ríos, Patricio, Kanagu, Laksmanan, Lathasumathi, Chokkalingam, and Stella, Chelladurai

Subjects
GASTROPODA, COASTS, BAYS, FEMALES
Abstract

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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226. Benthic macroinvertebrate communities in sites with native forest presence and absence in north Patagonia.

Author

De los Ríos-Escalante, Patricio, Esse, Carlos, Santander-Massa, Rodrigo, Saavedra, Pablo, and Encina-Montoya, Francisco

Subjects
FORAGING behavior, INVERTEBRATES, BENTHIC animals, WATER quality, BIODIVERSITY, FORESTS & forestry
Abstract

Copyright of Iheringia. Série Zoologia is the property of Fundacao Zoobotanica do Rio Grande do Sul and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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227. Anticoagulation Therapy by Age and Embolic Risk for Nonvalvular Atrial Fibrillation in Mexico, an Upper-Middle-Income Country: The CARMEN-AF Registry.

Author

Márquez, Manlio F., Baños-González, Manuel A., Guevara-Valdivia, Milton E., Vázquez-Acosta, Jorge, de los Ríos Ibarra, Manuel O., Aguilar-Linares, Julio A., Jiménez-Cruz, Marcelo, Matadamas-Hernández, Norberto, Camacho-Casillas, Rocío, Magaña-Magaña, Reynaldo, Rojel-Martínez, Ulises, Alcocer-Gamba, Marco A., Lara-Vaca, Susano, Rodríguez-Reyes, Humberto, Islava-Gálvez, Marco A., Betancourt-Hernández, Lidia E., Reyes-Reyes, Nicolás, Beltrán-Gámez, Miguel E., Cantú-Brito, Carlos, and Baños-Velasco, Alberto Z.

Abstract

Background: Documenting the patterns of oral anticoagulation therapy (OAT) is essential to prevent thromboembolic complications of nonvalvular atrial fibrillation (NVAF). Objective: To report the patterns of OAT according to age and thromboembolic risk in patients included in CARMEN-AF, a nationwide registry of NVAF in Mexico, an upper middle-income country. Material and methods: There were 1,423 consecutive patients ≥18 years old and with at least one thromboembolic risk factor enrolled in the CARMEN-AF Registry at their regular clinical visit during a three-year period. They were analyzed according to 1) age, 2) AF type, and 3) CHA2DS2-VASc score. Results: Overall, 16.4% of patients did not receive antithrombotic treatment, 19.4% received antiplatelet drugs (APD), 29.2% vitamin K antagonists (VKA), and 34.6% direct oral anticoagulants (DOAC). With increasing age, the proportion of subjects treated with VKA decreased significantly from 36.2% in subjects <65 years to 22.5% in those ≥75 years old (P <0.0001). Concomitantly, an increase in both APD and no antithrombotic treatment was observed with increasing age. DOAC were prescribed equally among all age groups (34.2% in <65, 36.0% in 65-74, and 33.9% in ≥75). According to the type of AF, VKA use was more common in patients with permanent AF (32.7%). A lower use of DOAC was observed in high thromboembolic risk subjects (33.6% in CHA2DS2-VASc ≥2) compared with the moderate risk group (41% in CHA2DS2-VASc = 1). Conclusions: VKA use for NVAF in Mexico decreased in relation to increasing age. The proportion of DOAC therapy was the same in all age groups. Nevertheless, elderly patients with high thromboembolic risk received a suboptimal thromboprophylaxis. These data could help to improve gaps in the implementation of global guidelines. Highlights: ™ CARMEN-AF is a nationwide multi-centric registry seeking to bridge the data gap on anticoagulation therapy for NVAF in Mexico. ™ Elderly patients are more prone to receive suboptimal OAT for NVAF. ⊲ DOAC were less frequently used in high thromboembolic risk patients (CHA2DS2-VASc ≥2). [ABSTRACT FROM AUTHOR]

Published
2020
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228. Morbilidad dermatológica en pacientes atendidos por la Patrulla Aérea Civil Colombiana, 2008-2018.

Author

Aguilar Medina, Nicolás, Van Den Enden Medina, Lucía, Jaramillo Ayerbe, Felipe, and Carvajal De los Ríos, Eduardo

Abstract

Copyright of Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica is the property of Asociacion Colombiana de Dermatologia y Cirugia Dermatologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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229. Evaluation of survival and metamorphosis of larvae of Caligus rogercresseyi (Boxshall and Bravo, 2000) (Crustacea, Copepoda) in Chile, depending on temperature, salinity and oxygen.

Author

Mardones, A., Gajardo, V., Pizarro, M. I., Augsburger, A., Vega, R., Encina, F., Pichara, C., and De los Ríos Escalante, P.

Subjects
INSECT larvae, METAMORPHOSIS, LARVAE, TEMPERATURE, SALINITY
Abstract

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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230. Analysis of urban metabolism in an informal settlement using the MuSIASEM method in Lima

Author

Acevedo-De-los-Ríos, Alejandra, Chumpitaz-Requena, Favio R., and Rondinel-Oviedo, Daniel R.

Abstract

By 2050, 68% of the global population will reside in cities, driving rapid urban growth and intensifying demand for scarce ecological resources within the Water-Food-Energy nexus. Social metabolism quantifies energy and material transformations with a social focus, building upon urban metabolism. Its application in resource-scarce informal settlements (ISs) has the potential to enhance their sustainability significantly. As community dynamics evolve, acknowledging society as a dynamic variable within this framework becomes increasingly relevant. Our study employs the Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism (MuSIASEM) framework, focusing on key variables: human activity, land use, money, energy, water, waste, and food. Based on surveys, interviews, GIS datasets, and statistical information, the study investigates the Ciudad de Gosen IS in Lima, Peru. The results show that, in the socio-economic dimension, 43% of the time employed is directed to the unpaid work sector. Notably, 71% of women and 29% of men spend a mean of 44 h/week/person caring for children or elderly. In the paid work sector, there are gender asymmetries; men have a salary 54% higher than women. In the ecological dimension, more than 78% of the homes have access to basic services, unlike other informal settlements in Latin America and Africa.

Published
2024
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231. Coinfections and In-Hospital Mortality in a Group of Patients With HIV/AIDS: A Longitudinal Study

Author

Valladales-Restrepo, Luis Fernando, Oyuela-Gutiérrez, María Camila, Díaz-Arteaga, Catalina, Torres-Campo, María Alejandra, Rengifo-Montes, Allyson, Erazo-De Los Ríos, Alfonso Sebastián, Sabogal-Ortiz, Alejandra, Machado-Duque, Manuel Enrique, Gaviria-Mendoza, Andrés, and Machado-Alba, Jorge Enrique

Abstract

Human immunodeficiency virus (HIV) is a global public health problem. Coinfections in HIV patients are frequent complications that increase their mortality. The aim of this study was to assess coinfections and in-hospital mortality in a group of patients infected with HIV in Colombia. A retrospective longitudinal study was carried out. Patients treated in 4 highly complex clinics in Colombia between 2015 and 2023 were included. The cases were identified from International Classification of Diseases codes related to HIV. Sociodemographic, clinical, laboratory and pharmacological variables were collected. Descriptive, bivariate, and multivariable analyses were performed. Of the 249 patients identified, 79.1% were men, and the median age was 38.0 years. Approximately 81.1% had a diagnosis of acquired immune deficiency syndrome (AIDS). Coinfections caused by Mycobacterium tuberculosis(24.1%) and Treponema pallidum(20.5%) were the most frequent. A total of 20.5% of the patients had sepsis, 12.4% had septic shock, and the fatality rate was 15.7%. Antibiotics and antifungals were used in 88.8% and 53.8%, respectively, of the patients. Patients with a diagnosis of HIV before admission, those infected with M. tuberculosis, and those who presented with sepsis were more likely to die, whereas patients who received antiretroviral agent treatment before admission presented a lower risk. In this study, most HIV patients were in an advanced stage of the disease. Coinfection with M. tuberculosiswas common and was associated with an increased risk of death. Previous HIV diagnosis and sepsis also increased the risk. Approximately half of the patients with a previous HIV diagnosis were receiving antiretroviral therapy and had a better prognosis.

Published
2024
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237. Translating Theory to Practice: Exploring Teachers' Raciolinguistic Literacies in Secondary English Classrooms.

Author

Seltzer, Kate and de los Ríos, Cati V.

Subjects
TEACHING methods, ENGLISH language, TEACHER education, LANGUAGE & languages, CRITICAL discourse analysis, ENGLISH as a foreign language
Abstract

This case study of two secondary English teachers integrates a critical translingual approach in two urban classrooms. Our inquiry is guided by two questions: (1) How did two teachers engage critical translingual approaches in their classrooms? (2) How did their positionalities shape implementation of these approaches? This article illustrates how teachers' stances and practices can be affected by their identities, pointing to the ways that diverse teachers must approach their translanguaging pedagogies with an understanding of raciolinguistic ideologies. We end with a call for teacher educators to help teachers engage the transgressive elements of translanguaging in English classrooms and hone their raciolinguistic literacies so that they can design classroom learning in more humanizing ways. [ABSTRACT FROM AUTHOR]

Published
2018
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238. Caracterización de los mecanismos de desconexión moral en escolares que asisten a una Institución Educativa pública del Departamento de Sucre- Colombia.

Author

Canchila Arrieta, Esquelin Manuel, Hoyos de los Ríos, Olga Lucía, and Valega Mackenzie, Sandra Johana

Abstract

Copyright of Zona Próxima is the property of Fundacion Universidad del Norte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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239. Tratamiento laparoscópico de masas anexiales en el embarazo: reporte de dos casos.

Author

Calle-G, Gustavo, Clavijo-R, Juan Manuel, de los Ríos P., José F., Salazar, Susana, and López-Ruiz, Claudia Cristina

Subjects
ADNEXAL diseases, PREGNANCY complications, SECOND trimester of pregnancy, OVARIAN cancer diagnosis, TRANSVAGINAL ultrasonography
Abstract

Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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240. Enfermedad cardiovascular progresiva en paciente bajo tratamiento con nilotinib

Author

Roa-Chamorro, Ricardo, Torres-Quintero, Lucía, García de los Ríos, Carlos, Puerta-Puerta, José Manuel, González-Bustos, Pablo, and Mediavilla-García, Juan Diego

Abstract

El desarrollo de enfermedad cardiovascular suele presentarse en sujetos con varios factores de riesgo cardiovascular. Sin embargo, existen otros condicionantes que pueden estar relacionados con la aparición de enfermedad cardiovascular, como pueden ser los fármacos antineoplásicos. Presentamos el caso de un varón de 63 años con muy alto riesgo cardiovascular, con antecedente personal de leucemia mieloide crónica en tratamiento con nilotinib que, a pesar de buen control metabólico, desarrolló una enfermedad arterial periférica grave y acelerada. La enfermedad arterial periférica se ha descrito en el 5-20% de los pacientes bajo tratamiento con nilotinib, siendo más frecuente en los sujetos con varios factores de riesgo cardiovascular.

Published
2020
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242. New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

Author

Malek, Rim, Arribas, Raquel L., Palomino-Antolin, Alejandra, Totoson, Perle, Demougeot, Celine, Kobrlova, Tereza, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Diez-Iriepa, Daniel, Godyń, Justyna, Panek, Dawid, Malawska, Barbara, Głuch-Lutwin, Monika, Mordyl, Barbara, Siwek, Agata, Chabchoub, Fakher, Marco-Contelles, José, Kiec-Kononowicz, Katarzyna, Egea, Javier, de los Ríos, Cristóbal, and Ismaili, Lhassane

Abstract

New tritarget small molecules combining Ca2+channels blockade, cholinesterase, and H3 receptor inhibition were obtained by multicomponent synthesis. Compound 3phas been identified as a very promising lead, showing good Ca2+channels blockade activity (IC50= 21 ± 1 μM), potent affinity against hH3R (Ki= 565 ± 62 nM), a moderate but selective hBuChE inhibition (IC50= 7.83 ± 0.10 μM), strong antioxidant power (3.6 TE), and ability to restore cognitive impairment induced by lipopolysaccharide.

Published
2019
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243. Tetrabenazine Facilitates Exocytosis by Enhancing Calcium-Induced Calcium Release through Ryanodine Receptors

Author

de Pascual, Ricardo, Álvarez-Ortego, Nuria, de los Ríos, Cristóbal, Jacob-Mazariego, Gema, and García, Antonio G.

Abstract

Vesicular monoamine transporter-2 is expressed in the presynaptic secretory vesicles membrane in the brain. Its blockade by tetrabenazine (TBZ) causes depletion of dopamine at striatal basal ganglia; this is the mechanism underlying its long-standing use in the treatment of Huntington’s disease. In the frame of a project aimed at investigating the kinetics of exocytosis from vesicles with partial emptying of their neurotransmitter, we unexpectedly found that TBZ facilitates exocytosis; thus, we decided to characterize such effect. We used bovine chromaffin cells (BCCs) challenged with repeated pulses of high K+. Upon repeated K+pulsing, the exocytotic catecholamine release responses were gradually decaying. However, when cells were exposed to TBZ, responses were mildly augmented and decay rate delayed. Facilitation of exocytosis was not due to Ca2+entry blockade through voltage-activated calcium channels (VACCs) because, in fact, TBZ mildly blocked the whole-cell Ca2+current. However, TBZ mimicked the facilitatory effects of exocytosis elicited by BayK8644 (L-subtype VACC agonist), an effect blocked by nifedipine (VACC antagonist). On the basis that TBZ augmented the secretory responses to caffeine (but not those of histamine), we monitored its effects on cytosolic Ca2+elevations ([Ca2+]c) triggered by caffeine or histamine. While the responses to caffeine were augmented twice by TBZ, those of histamine were unaffected; the same happened in rat cortical neurons. Hence, we hypothesize that TBZ facilitates exocytosis by increasing Ca2+release through the endoplasmic reticulum ryanodine receptor channel (RyR). Confirming this hypothesis are docking results, showing an interaction of TBZ with RyRs. This is consonant with the existence of a healthy Ca2+-induced-Ca2+-release mechanism in BCCs.

Published
2019
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244. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial

Author

Bhatt, Deepak L, Steg, Philippe Gabriel, Mehta, Shamir R, Leiter, Lawrence A, Simon, Tabassome, Fox, Kim, Held, Claes, Andersson, Marielle, Himmelmann, Anders, Ridderstråle, Wilhelm, Chen, Jersey, Song, Yang, Diaz, Rafael, Goto, Shinya, James, Stefan K, Ray, Kausik K, Parkhomenko, Alexander N, Kosiborod, Mikhail N, McGuire, Darren K, Harrington, Robert A, Santos, Vladimir, Jain, Ashit, Lendel, Irina, Russo, Michael, Haught, W H, Bouza, Manuel, Gogia, Harinder, Banerjee, Supratim, Kichura, George, Kantaros, Louis, Padron, Francisco, Passi, Rakesh, Stone, Jay, Pursley, Michael, D'Urso, Michael, Gardner, Timothy, Bennett, James, Nour, Khaled, Saini, Satinder, Zhang, Wenwu, Kumbhani, Dharam, Thomas, Dustin, Angiolillo, Dominick, Bertolet, Barry, Roman-Miranda, Amaury, Black, Robert, Manshadi, Ramin, Vaca, Carlos, Blanco, Antonio, Napoli, Mark, Brabham, David, Akyea-Djamson, Ayim, Desai, Pratik, Prasada, Sudhir, Khaira, Ajit, Forgosh, Leslie, Lieber, Ira, Umpierrez, Guillermo, Singal, Dinesh, Londono, Juan, Fraser, Neil, Ruiz, Jose, Vega, Damaris, Rodriguez, Lilia, Brown, Christopher, Syed, Faizullah, Aggarwala, Guarav, Eaves, William, Foster, Michael, Gupta, Dinesh, Avino, David, Asfour, Wail, Tonnessen, Glen, Zhao, Xue-Qiao, Singh, Narendra, Brockmyre, Andrew, Lepor, Norman, Shammas, Nicolas, Blick, David, Hearne, Steven, Prodafikas, John, Carell, Edgar, Izzo, Mark, Karim, Amin, Zakhary, Bosh, Atieh, Mahmoud, Leichter, Steven, Meadows, Charles, Hotchkiss, David, Abu-Fadel, Mazen, Wiseman, Alan, Bander, Jeffrey, Shah, Mahesh, Banerjee, Subhash, Ganim, Ricky, Sopko, Karen, Khan, Misal, Lloret, Ramon, Weirick, Troy, Mehta, Rajendra, Thadani, Udho, Bhargava, Anuj, Kosiborod, Mikhail, Moya, Jaynier, Staniloae, Cezar, Guerra, Yamirka D, Chhabra, Anil, Kosmicki, Douglas, Shaheen, Wassim, Mohammed, Akber, Bitters, J'Cinda, Pattanayak, Jan, Javier, Julian, Srivastava, Sunny, Phillips, Roland, Al-Amin, Jessie, Lillestol, Michael, Simpson, Patrick, Hazan, Lydie, Amin, Amit, Shah, Gopi, Korpas, Denes, Platt, Bruce, Dickert, Jim, Puente, Orlando, Hiotis, Louis, Doyle, Timothy, Rajan, Raj, Meholick, Alan, Gring, Christian, Hage-Korban, Elie, Feldman, Robert, Colfer, Harry, Butman, Samuel, Foster, Malcolm, Hart, Terence, Huling, Randall, Eshaghian, Shervin, Quintana, Ofsman, Cheung, Deanna, Handel, Franklin, Rodriguez, Mara, Suh, David, Gordon, Paul, Pressman, Gregg, Bauer, Michael, French, William, Barettella, Mark, Chatrathi, Sridhar, Suresh, Damodhar, Goldberg, Ronald, Huth, Mark, Younis, Liwa, Rahman, Aref, Mascolo, Richard, Welch, Michelle, Suneja, Randeep, Smith, Stephen, Shurmur, Scott, Agaiby, John, Jingo, Ahmad, Johnston, Janice, Beth, Mary, Vlastaris, Anthony, Kemp, Susan, Taheri, Hamid, Pereira, Edward, Deyoung, Michael, Hawa, Zafir, Smith, Ray, Galski, Thomas, Garas, Samer, Reddy, M, Sharma, Susheel, Hargrove, Joeseph, Treasure, Charles, Emerson, Ronald, Haddad, Tariq, Rohr, Kathryn, Levinson, Larry, Gaona, Raul, Uretsky, Barry, Maheshwari, Hiralal, Lee, Denny, Kinnaman, Stephanie, Singal, Robert, Geohas, Jeffrey, Gigliotti, Osvaldo, Raisinghani, Ajit, Khurana, Charanjit, Hella, Brent, Kelberman, Michael, Voyce, Steven, Singh, Sanjay, Lo, Eric, Singh, Pradeep, Goodfellow, Ross, Fischer, Stuart, Lorraine, Richard, Turner, Traci, Shanes, Jeffrey, Busch, Robert, Broker, Robert, Zaniewski, Michelle, Pounds, Kevin, Debs-Perez, Giselle, Ong, Stephen, Frandsen, Brad, Fullington, Douglas, Jaffrani, Naseem, Khan, Ahtaram, Lee, Marcus, Pouzar, Joe, Revtyak, George, Gonzalez, Julian, Nakhle, Samer, Murillo, Abel, Young, Douglas, Makam, Sashi, Syed, Mushtaq, Woolf, Kevin, Grena, Paul, Alfata, Sarab, Mahal, Sharan, Hoffman, David, Kizhakekuttu, Tinoy, Deering, Joseph, Bhavsar, Janak, Mikesell, Scott, Wilson, William, Wilson, Vance, El, Salah, Spinale, Francis, Kannarkat, Vinod, Rao, Sunder, Hanson, Lenita, Bertsch, John, Gonzalez-Ortiz, Elena, Severino, Norma, Willis, John, Schock, Joel, Bakhtari, Ladan, Gazmuri, Raul, Ansari, Saadat, Hall, Jason, Mehta, Arvind, Shealy, Neal, Zarich, Stuart, Singh, Deovrat, Vora, Kishor, Andrawis, Nabil, Molter, Darron, Maron, David, Cardona, Jose, D'Agostino, Ronald, Arshad, Tamjeed, Samaan, Rodney, Jones, David, Presser, Dale, Heath, John, Green, Sandy, Bittar, George, Henry, Sheldon, Korn, David, Schmedtje, John, Nadar, Venkatesh, Graham, Bruce, Labroo, Ajay, Clavijo, Leonardo, Roseman, Hal, Ledesma, Gilbert, Rosen, Robert, Dor, Isaac, Kirby, William, Sutton, Jennefer, Eder, Frank, Iteld, Bruce, Gomez-Cortes, Jose, Buchbinder, Maurice, Kasper, Joseph, Terrelonge, Antonio, Torres, Gustavo, Jagielo, Ted, Alvarez, Jose, Handelsman, Yehuda, Guillen, Mario, Richwine, Randall, Lewy-Alterbaum, Lorena, Corder, Clinton, Arvind, Moogali, Bolshoun, David, Mikhail, Magdy, Minton, Stephen, Alvarado, Odilon, Abbott, J, Cauthen, Brett, Welter, Ryan, Mintz, Randy, Cox, John, Quick, Annette, Weiss, Melvin, Dy, Johnny, Zebrack, James, Gandelman, Glenn, Hegde, Vinayak, Silver, Marc, DeGregorio, Michele, Lawson, William, Paa, Christopher, Bortnick, Anna, Krolick, Merrill, Sotolongo, Rodolfo, Cheirif, Jorge, Kumar, Priya, Nadar, Venkatesh, Jetty, Preetham, Patel, Ambar, Kruk, Mariusz, Kobielusz-Gembala, Iwona, Rewerska, Barbara, Madrzejewski, Adam, Milewski, Krzysztof, Cygler, Jerzy, Petryka-Mazurkiewicz, Joanna, Jastrzebski, Waldemar, Korecki, Janusz, Fil, Wojciech, Prokopczuk, Janusz, Bochenek, Anna, Wujkowski, Marek, Witek, Robert, Konczakowski, Piotr, Miekus, Pawel, Szczasny, Marcin, Musial, Wlodzimierz, Cymerman, Krzysztof, Lampart, Jacek, Mikosinski, Jacek, Szynal, Slawomir, Fares, Issa, Opolski, Grzegorz, Mazur, Stanislaw, Wozakowska-Kaplon, Beata, Bijata-Bronisz, Renata, Wierucki, Lukasz, Losa, Beata, Drelich, Grzegorz, Konieczny, Marek, Starczewski, Pawel, Pawlowicz, Lidia, Jesionowski, Pawel, Jurowiecki, Jaroslaw, Gniot, Jacek, Czyzycki, Mariusz, Stania, Karol, Kucharczyk-Bauman, Izabela, Busz-Papiez, Benita, Karczmarczyk, Agnieszka, Sudnik, Wanda, Koszek, Alina, Kolodziej, Piotr, Skwarna, Bartosz, Jaramillo, Nicolás, Jankowski, Maciej, Czochra, Wojciech, Kinasz, Leszek, Miklaszewicz, Beata, Stasinska, Teresa, Pluta, Wladyslaw, Basiak, Marcin, Rusicka, Teresa, Niedbal-Yahfouf, Izabela, Popenda, Grazyna, Korzeniak, Romuald, Mirek, Agnieszka, Mariankowski, Rafal, Wojnowski, Lukasz, Korol, Marek, Baszak, Jacek, Podolec, Piotr, Piesiewicz, Wojciech, Zurakowski, Aleksander, Luengas, Carlos, Skura, Marek, Pilecki, Piotr, Majchrzak, Piotr, Krzyzagórska, Ewa, Drozd, Marcin, Kaczmarek, Barbara, Sliwinska, Teresa, Zelazowska, Katarzyna, Sztembis, Rafal, Landa, Katarzyna, Matyszczak-Toniak, Lidia, Strojek, Krzysztof, Piepiorka, Marek, Malinowski, Robert, Górska, Maria, Stolarczyk-Sowa, Edyta, Romanowski, Leszek, Zinka, Elzbieta, Reszka, Zygfryd, Skierkowska, Joanna, Uzunow, Anna, Laskowska-Derlaga, Ewa, Puntus, Ekaterina, Kosmacheva, Elena D, Koziolova, Natalia, Pavlov, Prokhor, Supryadkina, Tatiana, Didenko, Yury, Kopylov, Philipp, Kazakov, Andrei, Aksentiev, Sergei, Vishneva, Elena, Repin, Alexey, Smolenskaya, Olga, Mantserova, Olga, Khrustalev, Oleg, Privalova, Elena, Konstantinov, Vladimir, Boldueva, Svetlana, Ezhov, Andrey, Chernyavsky, Alexander, Kamalov, Gadel, Galyavich, Albert, Zubeeva, Galina, Nechaeva, Galina, Shustov, Sergey, Dzhaiani, Nino, Treshkur, Tatiana, Osokina, Nataliya, Panov, Alexey, Shutemova, Elena, Makukhin, Valeriy, Kropotina, Tatiana, Tsyba, Larisa, Karpov, Yuri, Sizova, J M, Ballyuzek, Marina, Tarasov, Nikolay, Demchenko, Elena, Barbarash, Olga, Moiseev, Valentin, Markov, Valentin, Kuznetsov, Vadim, Viktorova, Inna, Sergienko, Igor, Ermoshkina, Lyudmila, Khasanov, Niyaz, Khlevchuk, Tatiana, Baglikov, Andrey, Shalaev, Sergey, Zonova, Elena, Reznik, Elena, Haisheva, Larisa, Morugova, Tatyana, Lomakin, Nikita, Vishnevsky, Alexander, Shvarts, Yuri, Magnitskaya, Olga, Mikhailusova, Marina, Pavlysh, Elena, Libov, Igor, Zateyschikova, Anna, Kostenko, Victor, Edin, Anton, Khovaeva, Yaroslava, Zakharov, Konstantin, Stryuk, Raisa, Khirmanov, Vladimir, Kanorskiy, Sergey, Yakushin, Sergey, Barabashkina, Anna, Li, Hongwei, Zhao, Qiang, Zhang, Jian, Ma, Jianhua, He, Yong, Luo, Ming, Zhang, Aidong, Zhang, Ningru, Chai, Yingru, Ma, Genshan, Wang, Hao, Liu, Zhigang, He, Lanjie, Song, Zhifang, Dong, Xiaolin, Tao, Liang, Li, Zhanquan, Su, Xi, Kong, Xiangqing, Niu, Heping, Ge, Junbo, Luo, Zhurong, Huang, Wenjun, Peng, Daoquan, Yuan, Zuyi, Milanova, Maria, Tenev, Doncho, Gogov, Antoni, Karageorgiev, Dimitar, Kolchev, Todor, Rusev, Nikolay, Georgieva, Nikolina, Kondov, Rumen, Rusinov, Veselin, Petrov, Ivo, Stanchev, Georgi, Konteva, Mariana, Dincheva, Adriana, Yaneva, Zdravka, Vatova, Ralitsa, Ilieva, Katya, Runev, Nikolai, Kolomanov, Borislav, Petrov, Ivan, Iliev, Nikolay, Tisheva, Snezhanka, Chompalova, Boryana, Tokmakova, Maria, Raev, Dimitar, Byanov, Kolyo, Markov, Dimitar, Mihov, Lenko, Mihov, Atanas, Milcheva, Nora, Minchev, Milen, Mollov, Mihail, Borisov, Borislav, Tihchev, Tihomir, Karakolev, Venelin, Dimov, Bojidar, Georgiev, Svetoslav, Smilov, Lachezar, Koo, Bon K, Ahn, Taehoon, Hong, Soon J, Yoon, Junghan, Oh, Seok K, Jeong, Myung H, Kim, Doo-Il, Chang, Kiyuk, Kim, Weon, Hahn, Joo-Yong, Cha, Kwang S, Lee, Jung-Hee, Choi, Si-Wan, Nam, Chang-Wook, Chae, In-Ho, Park, Yong H, Tahk, Seung-Jea, Shin, Won-Yong, Chae, Jei-Keon, Kim, Byung J, Bae, Jang-Whan, Park, Woo J, Rha, Seung W, Choi, Young J, Hwang, Jin-Yong, Park, Hun S, Baracioli, Luciano, Guimaraes, Fabio, Vasconcellos, Eduardo, Saraiva, José, Pereira, Adamastor, Santos, Queulla, Rossi, Paulo, Maia, Lilia, Madeira, Miguel, Pereira, Marcio, Botelho, Roberto, Reis, Gilmar, Eliaschewitz, Freddy, Borges, Joao, Nascimento, Carlos, Fortes, Jose A, de Souza, Weimar, Pimentel, Pedro, Hissa, Miguel, Franchetti, Marcos, Precoma, Dalton, Ortiz, Costantino, Hernandes, Mauro, Saporito, Wladmir, dos Santos, Fabio R, Kormann, Adrian, Neuenschwander, Fernando, Dutra, Oscar, Rassi, Nelson, Tanajura, Luiz, Souza, Juliana, Junior, Delcio S, Leaes, Paulo, Forte, Adriana, Bonansea, Teresa C, Marin, Jose, Machado, Bruno, Cerqueira, Maria J, Silva, Frederico, Michalaros, Yorghos, Manenti, Euler, Cercato, Cintia, Figueiredo, Estevao, Liu, Ming-En, Wang, Yi-Chih, Lee, Tsung-Ming, Fang, Chih, Wu, Yen-Wen, Ueng, Kwo-Chang, Sheu, Huey-Herng, Lai, Wen T, Hsieh, I-Chang, Chen, Zhih-Cherng, Lee, Mu-Jang, Chiang, Chern, Shyu, Kou-Gi, Hsia, Chien-Hsun, Mar, Guang-Yuan, Chan, Shih-Hung, Wu, Chih-Cheng, Tseng, Wei-Kung, Chang, Kuan-Cheng, Yeh, Hung-I, Wang, Ji-Hung, Hou, Charles, Sorokina, Inna, Dolzhenko, Maryna, Horoshko, Olha, Karpenko, Oleksandr, Rudenko, Leonid, Vakaliuk, Igor, Kulyk, Anna, Levchenko, Olena, Prokhorov, Oleksandr, Reshotko, Dmytro, Sorokivskyy, Mykhaylo, Velichko, Nataliia, Maslovskyi, Valentyn, Teliatnikova, Zinaida, Dotsenko, Sergiy, Krakhmalova, Olena, Kraiz, Igor, Zharinova, Viktoria, Bula, Larysa, Kaydashev, Igor, Molodtsov, Valeriy, Rasputina, Lesya, Pidlisna, Viktoriya, Lysunets, Olena, Kravchenko, Anatoliy, Glushko, Liubomyr, Khomazyuk, Tetyana, Svyshchenko, Yevgeniya, Parkhomenko, Oleksandr, Mankovsky, Boris, Abrahamovych, Orest, Yagensky, Andriy, Stanislavchuk, Mykola, Vasilyeva, Larisa, Sokolova, Liubov, Sychov, Oleg, Tseluyko, Vira, Kyrychenko, Igor, Rishko, Mykola, Furkalo, Sergiy, Gallo, Richard, Bertrand, Olivier, Mehta, Shamir, Constance, Christian, Sussex, Bruce, Zadra, Remo, Kouz, Simon, Chehayeb, Raja, Pandey, Amritanshu, Dion, Danielle, Bailey, Gordon, Hill, Laurie, Ramanathan, Krishnan, Dorsch, Micha, Nanji, Alykhan, Babapulle, Mohan, Montigny, Martine, Gosselin, Gilbert, Dehghani, Payam, Rupka, Dennis, Le May, Michel, Pichette, Francis, St-Maurice, Francois, Teefy, Patrick, Mansour, Samer, Kassam, Saleem, Cheung, Stephen, Siega, Anthony D, O'Keefe, Dennis, Sabbah, Eric, Bell, Alan, Chouinard, Guy, Wong, Brian, Miller, Mark, Gaudet, Daniel, Lachance, Pierre, Bata, Iqbal, Petrella, Robert, Gossard, Denis, Dumas, Richard, Ing, Douglas, Boyrazian, Hagop, Bessoudo, Ricardo, Huynh, Thao T, Hart, Randy, Belle-Isle, Jasmin, Shukla, Dinkar, Kelly, Allan, Mazza, Giuseppe, Cha, James, Henein, Sam, Frechette, Andre, Vizel, Saul, Liutkus, Joanne F, O'Mahony, Michael, Halperin, Frank, Kooy, Jacobus, Graham, John, Bailey, Allan, Wojcik, Ronald, Wilderman, Igor, Turi, Tibor, Motyovszki, Ákos, Merkely, Béla, Király, Csaba, Andrássy, Péter, Sárszegi, Zsolt, Fülöp, Tibor, Zilahi, Zsolt, Édes, István, Papp, Andras, Müller, Gábor, Czigány, Anna, Zólyomi, Szilárd, Korányi, László, Takács, János, Juhász, Ferenc, Benczur, Bela, Kancz, Sándor, Földi, András, Nagy, András C, Bakai, Judit, Greschik, István, Püski, László, Nagy, László, Kirschner, Róbert, Kuchar, Roman, Hajek, Petr, Busak, Ladislav, Michalik, Daniel, Matyasek, Ivo, Marusincova, Ivana, Kucera, Dusan, Jerabek, Ondrej, Honkova, Michaela, Dedek, Vratislav, Rihacek, Ivan, Kos, Pavel, Slaby, Josef, Machkova, Martina, Zidkova, Eva, Elbl, Lubomir, Grunfeldova, Hana, Carda, Jiri, Mrozek, Vladimir, Maly, Jiri, Milkovic, Richard, Malecha, Jan, Skalicka, Hana, Oral, Ivo, Krcova, Eva, Lisa, Libor, Belohlavek, Jan, Miklik, Roman, Cermak, Ondrej, Bednarova, Jana, Peroutka, Zdenek, Spinar, Jindrich, Wilke, Andreas, Appel, Karl-Friedrich, Taggeselle, Jens, Förster, Andreas, Toursarkissian, Nicole, Schmidt, Ekkehard, Bott, Jochen, Al-Zoebi, Ayham, Hennig, Dirk, Fischer, Sabine, Schön, Norbert, Sauter, Joachim, Simonis, Gregor, Nischik, Ruth, Rieker, Werner, Schenkenberger, Isabelle, Behnke, Thomas, Klausmann, Gerhard, Jeserich, Michael, Trenk, Dietmar, Weigmann, Ingo, Reuter, Hannes, Rummel, Reinhard, von Münchhausen, Candy, von Engelhardt, Charlotte, Horibe, Eishun, Shibasaki, Taro, Sato, Tomohiko, Kakuta, Tsunekazu, Michishita, Ichiro, Tan, Michinao, Ishiki, Ryoji, Aoyama, Takahiko, Higashiue, Shinichi, Niijima, Yawara, Idogaki, Akira, Hasegawa, Toru, Kiyosue, Arihiro, Tomobuchi, Yoshiaki, Kawamitsu, Katsunori, Kawasaki, Satsuki, Hata, Yoshiki, Fukui, Kazuki, Seki, Kozaburo, Takenaka, Takashi, Abe, Mitsuru, Utsu, Noriaki, Oono, Atsuyuki, Mitsuo, Kazuhisa, Sueyoshi, Atsushi, Hirohata, Atsushi, Tsujimoto, Mitsuru, Ueda, Osamu, Takase, Shinichi, Suzuki, Masahiro, Sakuragi, Satoru, Yamamoto, Fumi, Fujimoto, Noritaka, Kakinoki, Shigeo, Sugiura, Tatsushi, Sugino, Hiroshi, Nakamura, Toshihiro, Goto, Shinya, Kadokami, Toshiaki, Uehara, Hiroki, Ono, Masahiro, Yokoya, Koichi, Koike, Akihiro, Komatsu, Sei, Sonoda, Masahiro, Ueno, Hideki, Doi, Tomofumi, Takagi, Yuichiro, Fujimoto, Kazuteru, Eki, Yutaka, Okubo, Munenori, Sasaki, Kenichiro, van Eck, Martijn, Ronner, Eelko, The, Salem, van de Wal, Ruud, Nierop, Pieter, de Nooijer, Cornelis, The, Salem, The, Salem, Werner, Henri, Westendorp, Iris, van der Zwaan, Coen, Crijns, Hendrikus, Cornel, Jan H, Strikwerda, Sipke, Bos, Robert, de Melker, Edwin, Kuijper, Adrianus, Louwerenburg, Hans, Plomp, Jacobus, Dantzig, Jan-Melle, Prins, Francisco, van Kesteren, Henricus, Willems, Frank, Amoroso, Giovanni, Carnero, Gabriela, Duronto, Ernesto, Besada, Diego, Chacon, Carolina, Zangroniz, Pedro, Solis, Silvana, Liberman, Alberto, Sernia, Virginia, Alvarisqueta, Andres, Maffei, Laura, Vilamajo, Oscar G, García, Celso, Sicer, Maximiliano, Muntaner, Juan, Bordonava, Anselmo, Albisu, Juan, Zanini, Alejandra, Rista, Lucas, Hominal, Miguel, Estrada, José N, Prado, Aldo, Gosparini, Diego M, Schiavi, Beatriz, Castillo, Armando G, Ruíz, José G, Martinez, Guillermo R, López, Víctor G, Rosas, Enrique L, Lopez, Gabriel R, Cantu, Elias G, de los Ríos Ibarra, Manuel, Padilla, Francisco P, Carrasco, Jose P, Carrillo, Luis V, García, Joel D, Askar, Alfredo N, Salinas, Carlos A, Gamba, Marco A, Sanchez, Carlos G, Cantú, Arnulfo G, Sánchez, Raul V, Madrigal, Jaime C, Urbano, Rafael H, Romo, Andrés Í, González Juanatey, José R, Racugno, Paolo, Fillat, Angel C, de la Torre Hernández, José M, Peláez, Juan A, Cortada, Jorge B, Pavia, Pablo G, Navarro, Manuel J, Asenjo, Roberto M, Díaz, Francisco F, Peligero, Eduard B, Manterola, Fernando A, Ortiz, Antonio F, Mediavilla García, Juan D, Ortuño, Francisco M, Vera, Tomás R, González, Alfonso S, Viñas, Jaime A, Fernández Portales, Francisco J, Mayordomo, Petra S, Ojeda, Francisco B, Domínguez, Antonio R, González, Rosa S, Guerrero, Diego B, Ruiz Nodar, Juan M, Marimon, Xavier G, Margáez, José G, Aguilera, Roberto M, Díaz Fernández, José F, Zamorano Gómez, José L, González, Vicente B, del Blanco, Bruno G, Pérez, Ignacio P, Moreno, Mercé R, Ereño, Ainhoa R, García Lledó, José A, Prieto, Juan, Villablanca, Alex, Raffo, Carlos, Pincetti, Christian, Conejeros, Carlos, Roman, Oscar, Rodriguez, Manuel, Varleta, Paola, Goldberg, Cindy, Sandoval, Jorge, Arriagada, German, Leon, Lucio, Potthoff, Sergio, Cobos, Jorge, Figueroa, Christian, Makotoko, Ellen, Fourie, Nyda, Burgess, Lesley, Nortje, Hendrik, Theron, Rust, Pillai, Perumal, Ranjith, Naresh, Trokis, Julien, Pillay, Soobramoney, Reddy, Jeevren, Nunkoo, Theema, Kapp, Cornelia, Urbach, Dorothea, Distiller, Lawrence, Horak, Adrian, van Zyl, Louis, Coetzee, Kathleen, Punt, Zelda, Bayat, Junaid, Dawood, Saleem, Mitha, Ismail, Padayachee, Trevenesan, Hoosen, Farzana, Dalby, Anthony, Prabhavathi, Gowdaiah, Prakash, Mehta, Vimal, Chag, Milan, Gadkari, Milind, Ramamurthee, Kannaiyan, Das, Asit, Sawhney, Jitendra S, Banerjee, Suvro, Sathe, Prachee, Adhyapak, Srilakshmi, Nguyen, Tuan, Pham, Vinh, Do, Huan, Nguyen, Anh, Nguyen, Hien, Truong, Binh, Jamil-Copley, Shahnaz, Lang, Chim, Pell, Alastair, Zaman, Azfar, Storey, Robert, Swanson, Neil, Smith, Simon, Sharman, David, Braganza, Denise, Hammond, Peter, Moriarty, Andrew, Bain, Stephen, Pye, Maurice, Sharp, Andrew, Blagden, Mark, Randeva, Harpal, Myhill, Timothy, Viswanathan, Girish, Keeling, Philip, Clifford, Piers, Saxena, Manish, Lyons, Kristopher, McMurray, John, Jaafar, Feeroz, Murphy, Clare, Cartwright, Simon, Abouglila, Kamal, Antalik, Lubomir, Krajci, Peter, Urban, Miroslav, Fazekas, Frantisek, Pella, Daniel, Koleny, Daniel, Vykoukalova, Tatiana, Macek, Vladimir, Vinanska, Daniela, Jamriskova, Livia, Such, Slavomir, Fulop, Peter, Farsky, Stefan, Bugan, Viliam, Strbova, Jaroslava, Micko, Karol, Palka Jr, Juraj, Sivak, Vladimir, Kristensen, Dalby, Refsgaard, Jens, Holmvang, Lene, Dixen, Ulrik, Nielsen, Henrik, Egstrup, Kenneth, Jensen, Lisette O, Sykulski, Roman, Rasmussen, Ole, Andries, Alin, Luckow, Anders, Nielsen, Gitte, Sørensen, Torben, Wongvipaporn, Chaiyasith, Chamnarnphol, Noppadol, Srimahachota, Suphot, Sansanayudh, Nakarin, Kuanprasert, Srun, Tresukosol, Damras, Sookananchai, Bancha, Kanadasi, Mehmet, Ozcan, Turkay, Kucuk, Murathan, Ongen, Zeki, Okuyan, Ertugrul, Arat, Alev, Acikel, Sadik, Yalcin, Ahmet, Guray, Umit, Ceyhan, Ceyhun, Ozer, Necla, Arslan, Sakir, Angerås, Oskar, Johnston, Nina, Weiderman, Ann-Charlotte, Bandh, Stellan, Hansen, Ole, Larnefeldt, Hans, Kusiak, Dawid, Lindholm, Carl-Johan, Hedman, Anders, Erlinge, David, Curiac, Dan, Lundman, Pia, Zucconi-Mazzini, Roberto, Aladellie, Layth, Jensen, Jens, Verwerft, Jan, Vrolix, Mathias, Faes, Dirk, Striekwold, Harry, Sinnaeve, Peter, Timmermans, Patrick, Guedes, Antoine, Delforge, Marc, Nimmegeers, Jan, Stammen, Francis, Buysschaert, Ian, Hoffer, Etienne, Hollanders, Geert, Vervoort, Geert, Coussement, Patrick, de Maeseneire, Stefan, Janssens, Luc, Gravdal, Stein A, Risberg, Knut, Gullestad, Lars, Hofseth, Ola D, Nilsen, Dennis, Lappegård, Knut T, van den Heuvel, Christian, Gibbs, Charlotte, Khusrawi, Alamdar, Arora, Satish, Tomala, Tadeusz, Kjærnli, Thorbjørn, Berg-Johansen, Jan, Hagemeier, Robert, Skjelvan, Gunnar, Colquhoun, David, Amerena, John, Morbey, Claire, Hammett, Christopher, Dart, Anthony, Lehman, Ronald, Hamilton, Andrew, Worthley, Matthew, Purnell, Peter, Whelan, Alan, MacIsaac, Richard, Arya, Ktut, Linjawi, Sultan, Proietto, Joseph, Prasad, Lakshman, Rodriguez, Aldo, Godoy, Armando, Rodriguez, Victor, Berrospi, Percy, Chavez, Carlos, Negron, Sandra, Heredia, Javier, Medina, Felix, Manrique, Helard, Cabrera, Walter, Cordova, Fernando, Quinteros, Trinidad, Haro, Jaime M, Regalado, Susana, Guitton, Javier, Arbanil, Hugo, Pansieri, Michel, Decoulx, Eric, Goube, Pascal, de Labriolle, Axel, Labeque, Jean N, Range, Gregoire, Cottin, Yves, Montalescot, Gilles, Cayla, Guillaume, Danchin, Nicolas, Angoulvant, Denis, Ferrario, Emile, Elbaz, Meyer, Dubreuil, Olivier, Steg, Philippe G, Fontaine, Caroline, Sorbets, Emmanuel, Omer, Hafiz, Al-Saif, Shukri, Al-Faleh, Hussam, Al-Shehri, Abdullah, Alshehri, Halia, Bazari, Rasha, Hei, Pak, Ying, Man, Chan, Michael, Wong, Michelle, Ma, Ronald, Siu, Shing C, Tsang, Chiu C, Ferrario, Maurizio, Assanelli, Emilio, Senni, Michele, Piatti, Piermarco, Calabrò, Paolo, Urbinati, Stefano, Michisanti, Massimo, Varbella, Ferdinando, de Cosmo, Salvatore, Trevisan, Roberto, Bellotti, Sandro, Di Pasquale, Giuseppe, Bongo, Angelo S, Uguccioni, Massimo, Mannucci, Edoardo, Mauro, Ciro, Ragonese, Mauro, Fresco, Claudio, Turturo, Maurizio, Marcucci, Rossella, Lievano Triana, Manuel J, Arana, Camilo, Accini, Jose, Botero, Rodrigo, Muzyk-Osikowicz, Marlena, Dada, Fredy T, Vallejo, Gregorio S, Manzur, Fernando, Isaza, Daniel, Molina, Dora, Mesa, Juan G, Quintero, Alvaro, Nyman, Kai, Mäkelä, Jyrki, Strand, Jorma, Nieminen, Sakari, Taurio, Jyrki, Kuusela, Matti, Valle, Timo, Pietilä, Mikko, Kekki, Sakari, Strandberg, Timo, Klutstein, Marc, Greenberg, Gabriel, Rozenman, Yoseph, Chorin, Ehud, Roguin, Ariel, Lewis, Basil, Bashkin, Amir, Tan, Edgar, Prado, Jose P, Ferrolino, Arthur, Babilonia, Noe, Barbas, Benny, Matiga, Generoso, Coching, Raul M, Drexel, Heinz, Brath, Helmut, Schnack, Christoph, Hanusch, Ursula, Fließer-Görzer, Evelyn, Paulweber, Bernhard, Ebenbichler, Christoph, Prager, Rudolf, Huber, Kurt, Wolzt, Michael, Auer, Johann, Berger, Rudolf, Schernthaner, Gerit-Holger, Stanciulescu, Gabriela, Creteanu, Mihai, Spiridon, Marilena, Dobreanu, Viorica, Vinereanu, Dragos, Iosipescu, Laura C, Istratoaie, Octavian, Coman, Ioan, Militaru, Constantin, Cinteza, Mircea, Bhatt, Deepak L, Fox, Kim, Harrington, Robert A, Leiter, Lawrence A, Mehta, Shamir R, Simon, Tabassome, Andersson, Marielle, Himmelmann, Anders, Steg, Philippe G, Diaz, Rafael, Amerena, John, Huber, Kurt, Sinnaeve, Peter R, Nicolau, José C, Kerr Saraiva, José F, Petrov, Ivo, Leiter, Lawrence A, Mehta, Shamir R, Corbalán, Ramón, Ge, Junbo, Zhao, Qiang, Botero, Rodrigo, Widimský, Petr, Kristensen, Steen D, Hartikainen, Juha, Danchin, Nicolas, Darius, Harald, Tse, Hung F, Kiss, Robert G, Pais, Prem, Lev, Eli, de Luca, Leonardo, Goto, Shinya, Ramos López, Gabriel A, Cornel, Jan H, Kontny, Frederic, Medina, Felix, Babilonia, Noe A, Opolski, Grzegorz, Vinereanu, Dragos, Zateyshchikov, Dmitry A, Ruda, Mikhail, Elamin, Omer, Kovář, František, Dalby, Anthony J, Jeong, Myung H, Bueno, Héctor, James, Stefan K, Chiang, Chern-En, Tresukosol, Damras, Ongen, Zeki, Ray, Kausik K, Parkhomenko, Alexander, McGuire, Darren K, Kosiborod, Mikhail N, Nguyen, Tuan Q, Andersson, Marielle, Chen, Jersey, Himmelmann, Anders, Leonsson-Zachrisson, Maria, and Ridderstråle, Wilhelm

Abstract

Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor.

Published
2019
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245. Delineation of the Olive Pollen Proteome and Its Allergenome Unmasks Cyclophilin as a Relevant Cross-Reactive Allergen

Author

San Segundo-Acosta, Pablo, Oeo-Santos, Carmen, Benedé, Sara, de los Ríos, Vivian, Navas, Ana, Ruiz-Leon, Berta, Moreno, Carmen, Pastor-Vargas, Carlos, Jurado, Aurora, Villalba, Mayte, and Barderas, Rodrigo

Abstract

Olive pollen is a major allergenic source worldwide due to its extensive cultivation. We have combined available genomics data with a comprehensive proteomics approach to get the annotated olive tree (Olea europaeaL.) pollen proteome and define its complex allergenome. A total of 1907 proteins were identified by LC–MS/MS using predicted protein sequences from its genome. Most proteins (60%) were predicted to possess catalytic activity and be involved in metabolic processes. In total, 203 proteins belonging to 47 allergen families were found in olive pollen. A peptidyl–prolyl cis–transisomerase, cyclophilin, produced in Escherichia coli, was found as a new olive pollen allergen (Ole e 15). Most Ole e 15-sensitized patients were children (63%) and showed strong IgE recognition to the allergen. Ole e 15 shared high sequence identity with other plant, animal, and fungal cyclophilins and presented high IgE cross-reactivity with pollen, plant food, and animal extracts.

Published
2019
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246. Psychometric properties of a Spanish translation of the Functionality Appreciation Scale (FAS) in adults from Colombia.

Author

Mebarak, Moisés, Todd, Jennifer, Coneo, Ana Maria Chamorro, Muñoz-Alvis, Andrés, Polo-Vargas, Jean David, De Los Reyes Aragón, Carlos, Herrera, Maura, Martínez, Martha, Hoyos De Los Ríos, Olga Lucía, Mendoza, Juan, Carrasquilla, Angélica, and Swami, Viren

Abstract

The 7-item Functionality Appreciation Scale (FAS) measures the extent of an individual's appreciation of their body for what it can do and is capable of doing. Although the FAS has been widely used in diverse linguistic contexts, it has not been previously translated into Spanish. Here, we examined the psychometric properties of a novel Spanish translation of the FAS in Colombian adults. A total of 1420 university students from Colombia (804 women, 616 men) completed the FAS, as well as additional validated measures. Exploratory and confirmatory factor analyses in separate subsamples supported a unidimensional model of FAS scores. The FAS evidenced scalar invariance across gender identity, with men having significantly higher FAS scores than women (Cohen's d = 0.18). FAS scores were also found to have adequate composite reliability, as well as adequate convergent (significant associations with body appreciation, appearance evaluation, and eating disorder psychopathology) and concurrent validity (significant associations with self-esteem, life satisfaction, and gratitude). Functionality appreciation incrementally predicted life satisfaction in women, but not in men. Overall, these results suggest that the Spanish FAS is a psychometrically valid and reliable tool for the assessment of functionality appreciation in university-aged populations from Colombia. • Functionality Appreciation Scale (FAS) has unidimensional structure in Colombian adults. • FAS is invariant across gender, with men having higher scores than women. • FAS scores have adequate composite reliability, and convergent and concurrent validity. • Evidence of incremental validity supported in women, but not men. [ABSTRACT FROM AUTHOR]

Published
2023
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248. Cistouretropexia laparoscópica tipo Burch para el tratamiento de la incontinencia urinaria de esfuerzos: seguimiento a largo plazo

Author

Carlos Buitrago D, José F De los Ríos P, Adriana Arango M, Gustavo Calle G, Juan Castañeda R, Eduardo Serna A, Henry Muñoz S, and Ricardo Vásquez R

Subjects
laparoscopic Burch colposuspension, Stress urinary incontinence, índice de Sandvik, Obstetrics and Gynecology, Incontinencia urinaria de esfuerzo, colposuspensión laparoscópica de Burch, Sandvik s index
Abstract

Objetivos: Conocer las complicaciones, las tasas de cura subjetiva y valoración con el índice de severidad de Sandvik a largo plazo de pacientes en quienes se realizó cistouretropexia laparoscópica tipo Burch para la corrección de su incontinencia urinaria de esfuerzo (IUE). Método: Análisis descriptivo, retrospectivo. Nivel de evidencia III. Se incluyeron las pacientes con diagnóstico de IUE tipo Blaivas IIB, a quienes se les practicó Burch laparoscópico en la Clínica del Prado y Profamilia Medellín, entre los años 2003 y 2007. Las variables principales a evaluar fueron edad, tiempo quirúrgico, cura subjetiva, índice de severidad de Sandvik y complicaciones. Resultados: Se analizaron 72 pacientes con promedio de edad de 46,57 ± 9,54 años. El tiempo promedio de seguimiento fue de 24,4 meses (rango: 9,0-55,8 meses). El tiempo quirúrgico promedio fue de 79,83 minutos (rango: 44-160 minutos). Refirieron cura subjetiva 56 pacientes (77,8%). El índice de severidad de Sandvik muestra que a largo plazo 56,9% pacientes estaban secas con remisión completa de los síntomas y el 13,8% pacientes tenían pérdidas leves. Conclusiones: El Burch laparoscópico es una opción efectiva para el manejo de la incontinencia urinaria de esfuerzo tipo Blaivas IIB. Provee tasas de curación subjetiva a largo plazo similares a otros tipos de tratamiento. Es una opción más a tener en cuenta en el manejo de la IUE, en especial aquellas pacientes con patologías asociadas que se beneficien del abordaje por laparoscopia. Objectives: To describe the subjective cure rate, the score of the Sandvik test and the complications after la-paroscopic Burch in patients with stress urinary incontinence (SUI). Methods: Prospective descriptive study. We included all patients diagnosed with SUI Blaivas type IIB, and operated on by laparoscopy in two reference institutions between 2003 and 2007. Results: We analyzed 72 patients with an average age of 46.57 ± 9.54 years. The average follow-up was 24.4 months, with a minimum of 9 and a maximum of 55.8. The average operating time in 29 patients in which we only performed laparoscopic Burch with or without colpo-rrhaphy was 93.7 minutes (55-180 minutes); 56 patients (77.8%) reported subjective cure. The Sandvik's severity index found 56.9% dry patients and 13.8% with mild losses. Conclusion: The laparoscopic management may be useful in some patients, especially those who will be carried to laparoscopy by some other indication. Subjective cure rates are similar to other types of surgery.

Published
2011

249. Histerectomía laparoscópica total: manejo ambulatorio. Experiencia Clínica del Prado, Medellín, Colombia

Author

Calle G, Gustavo, De Los Ríos P, José F, Castañeda R, Juan D, Serna A, Eduardo, Vásquez R, Ricardo A, Arango M, Adriana M, Muñoz S, Henry, Escobar F, Álvaro J, Mejía B, Ana M, and García S, Germán

Subjects
satisfacción de usuaria, surgical complication, user satisfaction, complicaciones quirúrgicas, Histerectomía laparoscópica ambulatoria, Outpatient laparoscopic hysterectomy
Abstract

Objetivo: Describir los resultados de la histerectomía laparoscópica total ambulatoria. Método: Se analizan 297 pacientes sometidas a histerectomía laparoscópica total y que fueron dadas de alta luego de la recuperación anestésica, entre mayo de 2007 y marzo de 2008. Se requería una puntuación de menos de 5 en la escala visual análoga del dolor para el alta. Resultados: El promedio de edad fue de 42 años, el tiempo quirúrgico de 79,1 minutos, el sangrado estimado fue de 37,1 ml, el tiempo promedio de estancia total fue de 9,4 horas con un tiempo promedio de estancia postoperatoria de 5,4 horas. La tasa de complicaciones postoperatorias fue de 11,8% y la de readmisiones del 3,3%. El promedio de Escala Visual Análoga del dolor para la primera noche fue de 4,2 puntos. El 6% de las pacientes presentaron vómitos en su domicilio. El 99% de las pacientes recomendarían este tipo de manejo. Conclusiones: El manejo ambulatorio después de histerectomía laparoscópica total es posible, seguro y bien evaluado por las pacientes. Este manejo no conlleva un mayor riesgo de complicaciones y la tasa de readmisiones es baja. Objective: To describe the results of a group of patients in which total laparoscopic hysterectomy was done as an outpatient procedure. Methods: We included 297 patients who were undergone to laparoscopic total hysterectomy, and were discharge to their home after recovery of anesthesia from may 2007 to march 2008. It was necessary to have a punctuation less than 5 in the analogue visual scale to be sent at home. Results: Mean age was 42 years, surgical time 79.1 minutes, estimated blood loss 37.1 ml, overall length of stay 9.4 hours, postoperative length of stay 5.4 hours. Postoperative complication rate was 11.8%, readmission rate was 3.3%. Mean VAS Score for pain during the first night was 4.2 points; 6% of patients vomited at home. Mean VAS Score for satisfaction with ambulatory management was 9.5, and 99% of the patients would recommend this type of management. Conclusions: Ambulatory management after total laparoscopic hysterectomy is possible, safe and well evaluated by patients. It does not impose a higher risk of complications and readmission rate is low.

Published
2011

250. HISTERECTOMÍA LAPAROSCÓPICA TOTAL, CURVA DE APRENDIZAJE: EXPERIENCIA DE CLÍNICA DEL PRADO, MEDELLÍN, COLOMBIA

Author

Adriana Arango M, Luis Almanza P., Ricardo Vásquez R, Ana Cristina Mejía B., Juan Castañeda R, Eduardo Serna A, Giovanni Riaño C., José F De los Ríos P, and Gustavo Calle G

Subjects
Laparoscopic hysterectomy, learning curve, Obstetrics and Gynecology, curva de aprendizaje, complicaciones quirúrgicas, surgical complications, Histerectomía laparoscópica total
Abstract

Objetivos: Comparar la curva de aprendizaje en histerectomía laparoscópica total (HLT) de 4 ginecólogos en la Clínica del Prado, Medellín, Colombia. Determinar el número de cirugías necesarias para alcanzar un tiempo quirúrgico promedio de 90 minutos, disminuir la laparoconversiones a un 3% o menos y disminuir las complicaciones totales a menos del 10%. Método: Se realizó un estudio de cohorte prospectivo que incluyó 626 pacientes operadas por 4 ginecólogos laparoscopistas con técnica y equipamiento quirúrgico similar. Se formaron 4 grupos de pacientes de acuerdo al orden en la casuística de cada uno de ellos. Resultados: El tiempo quirúrgico promedio de 93 minutos se logra con las primeras 50 HLT. El realizar entre 50-100 HLT baja las tasas de laparoconversión a 1,9%. La tasa de complicaciones en la sumatoria de la primera y segunda cohorte es de 19,4% y la tasa de complicaciones totales en la tercera cohorte es de 8,7% (RR: 0,45; IC95%: 0,26-0,78) la cual permanece en el límite deseado (10%) en la cuarta cohorte. Conclusiones: La curva de aprendizaje en HLT para lograr un promedio de tiempo de cirugía de 90 minutos se logra con las primeras 50 histerectomías. A pesar de las limitaciones metodológicas, el presente estudia revela que para lograr la destreza máxima toma entre 50-100 histerectomías para lograr laparoconversiones menores del 3% y entre 100-150 histerectomías para lograr complicaciones totales inferiores a 10%. Objective: To compare the learning curve in total laparoscopic hysterectomy (HLT) from four gynecologists in the Clínica del Prado, Medellín, Colombia. To determine the number of surgeries required to achieve an average surgical time of 90 minutes, to reduce laparoconversions to 3% or less and to reduce total complications to less than 10%. Method: We performed a prospective cohort study including 626 patients operated by four gynecologists laparoscopist with similar technique and surgical equipment. We made four groups of patients according to the order in the cases of each one. Results: The mean operative time of 93 minutes is achieved with the first 50 HLT. Doing 50-100 HLT, laparoconversions rates low to 1.9%. The complication rate in the sum of first and second cohort is 19.4% and the total complication rate in third cohort is 8.7% (RR: 0.45; 95%CI 0.26-0.78) which remains in the desired limit (10%) in fourth cohort. Conclusions: HLT learning curve to achieve an average surgical time of 90 minutes is achieved with the first 50 hysterectomies. Despite the methodological limitations this study, shows that to achieve máximum expertise, it takes between 50-100 hysterectomies to achieve laparoconversions less than 3%, and between 100-150 hysterectomies to achieve total complications lower than 10%.

Published
2010

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