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1,906 results on '"D’Alton, Mary E"'

202. The National Children's Study: a 21-year prospective study of 100 000 American children

Author

Landrigan, Philip J., Trasande, Leonardo, Thorpe, Lorna E., Gwynn, Charon, Lioy, Paul J., D'Alton, Mary E., Lipkind, Heather S., Swanson, James, Wadhwa, Pathik D., Clark, Edward B., Rauh, Virginia A., Perera, Frederica P., and Susser, Erzra

Subjects
Environmental aspects, Child development -- Environmental aspects
Abstract

ENVIRONMENTAL EXPOSURES IN early life can influence development, impair health, and increase risk of disease and dysfunction. (1-3) Chemical, physical, and psychosocial factors have all been shown to exert great [...], Prospective, multiyear epidemiologic studies have proven to be highly effective in discovering preventable risk factors for chronic disease. Investigations such as the Framingham Heart Study have produced blueprints for disease prevention and saved millions of lives and billions of dollars. To discover preventable environmental risk factors for disease in children, the US Congress directed the National Institute of Child Health and Human Development, through the Children's Health Act of 2000, to conduct the National Children's Study. The National Children's Study is hypothesis-driven and will seek information on environmental risks and individual susceptibility factors for asthma, birth defects, dyslexia, attention-deficit/hyperactivity disorder, autism, schizophrenia, and obesity, as well as for adverse birth outcomes. It will be conducted in a nationally representative, prospective cohort of 100 000 US-born children. Children will be followed from conception to 21 years of age. Environmental exposures (chemical, physical, biological, and psychosocial) will be assessed repeatedly during pregnancy and throughout childhood in children's homes, schools, and communities. Chemical assays will be performed by the Centers for Disease Control and Prevention, and banks of biological and environmental samples will be established for future analyses. Genetic material will be collected on each mother and child and banked to permit study of gene-environment interactions. Recruitment is scheduled to begin in 2007 at 7 Vanguard Sites and will extend to 105 sites across the United States. The National Children's Study will generate multiple satellite studies that explore methodologic issues, etiologic questions, and potential interventions. It will provide training for the next generation of researchers and practitioners in environmental pediatrics and will link to planned and ongoing prospective birth cohort studies in other nations. Data from the National Children's Study will guide development of a comprehensive blueprint for disease prevention in children. Key Words National Children's Study, epidemiology, asthma, attention-deficit/hyperactivity disorder, autism, schizophrenia, obesity Abbreviations CVD--cardiovascular disease NICHD--National Institute of Child Health and Human Development CDC--Centers for Disease Control and Prevention NCS-- National Children's Study HPV-- high production volume NCPP--National Collaborative Perinatal Project CHDS--Child Health Development Study NIH--National Institutes of Health

Published
2006

209. First-trimester or second-trimester screening, or both, for Down's syndrome

Author

Malone, Fergal D., Ball, Robert H., Canick, Jacob A., Nyberg, David A., Comstock, Christine H., Bukowski, Radek, Gross, Susan J., Berkowitz, Ricahrd L., Dugoff, Lorraine, Rudnicka, Alicja R., Hackshaw, Allan K., Lambert-Messerlian, Geralyn, Wald, Nicholas J., and D'Alton, Mary E.

Subjects
Down syndrome -- Diagnosis, Down syndrome -- Care and treatment, Pregnant women -- Health aspects, Medical screening
Abstract

The First- and Second-Trimester Evaluation of Risk (FASTER) Trial is conducted with the aim of giving direct comparative data on lately available screening approaches to Down's syndrome from a large population followed prospectively. First-trimester combined screening at 11 weeks of gestation is found to be better than second-trimester quadruple screening however at 13 weeks has results similar to second-trimester quadruple screening.

Published
2005

214. Putting the “M” back in maternal–fetal medicine

Author

DʼAlton, Mary E., Bonanno, Clarissa A., Berkowitz, Richard L., Brown, Haywood L., Copel, Joshua A., Cunningham, Gary F., Garite, Thomas J., Gilstrap, Larry C., III, Grobman, William A., Hankins, Gary D.V., Hauth, John C., Iriye, Brian K., Macones, George A., Martin, James N., Jr, Martin, Stephanie R., Menard, Kathryn M., OʼKeefe, Daniel F., Pacheco, Luis D., Riley, Laura E., Saade, George R., and Spong, Catherine Y.

Published
2013
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218. Measurement of hemorrhage-related severe maternal morbidity with billing versus electronic medical record data.

Author

Friedman, Alexander M., Oberhardt, Matthew, Sheen, Jean-Ju, Kessler, Alan, Vawdrey, David, Green, Robert, D'Alton, Mary E., and Goffman, Dena

Abstract

Measurement of obstetric hemorrhage-related morbidity is important for quality assurance purposes but presents logistical challenges in large populations. Billing codes are typically used to track severe maternal morbidity but may be of suboptimal validity. The objective of this study was to evaluate the validity of billing code diagnoses for hemorrhage-related morbidity compared to data obtained from the electronic medical record. Deliveries occurring between July 2014 and July 2017 from three hospitals within a single system were analyzed. Three outcomes related to obstetric hemorrhage that are part of the Centers for Disease Control and Prevention definition of severe maternal morbidity (SMM) were evaluated: (i) transfusion, (ii) disseminated intravascular coagulation (DIC), and (iii) acute renal failure (ARF). ICD-9-CM and ICD-10-CM for these conditions were ascertained and compared to blood bank records and laboratory values. Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) with 95% confidence intervals (CI) were calculated. Ancillary analyses were performed comparing codes and outcomes between hospitals and comparing ICD-9-CM to ICD-10-CM codes. Comparisons of categorical variables were performed with the chi-squared test. T-tests were used to compare continuous outcomes. 35,518 deliveries were analyzed. 786 women underwent transfusion, 168 had serum creatinine ≥1.2 mg/dL, and 99, 40, and 16 had fibrinogen ≤200, ≤150, and ≤100 mg/dL, respectively. Transfusion codes were 65% sensitive (95% CI 62–69%) with a 91% PPV (89–94%) for blood bank records of transfusion. DIC codes were 22% sensitive (95% CI 15–32%) for a fibrinogen cutoff of ≤200 mg/dL with 15% PPV (95% CI 10–22%). Sensitivity for ARF was 33% (95% CI 26–41%) for a creatinine of 1.2 mg/dL with a PPV of 63% (95% CI 52–73%). Sensitivity of ICD-9-CM for transfusion was significantly higher than ICD-10-CM (81%, 95% CI 76–86% versus 56%, 95% CI 51–60%, p <.01). Evaluating sensitivity of codes by individual hospitals, sensitivity of diagnosis codes for transfusion varied significantly (Hospital A 47%, 95% CI 36–58% versus Hospital B 63%, 95% CI 58–67% versus Hospital C 80%, 95% CI 74–86%, p <.01). Use of administrative billing codes for postpartum hemorrhage complications may be appropriate for measuring trends related to disease burden and resource utilization, particularly in the case of transfusion, but may be suboptimal for measuring clinical outcomes within and between hospitals. [ABSTRACT FROM AUTHOR]

Published
2022
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222. CONTRIBUTORS

Author

Abrahams, Vikki M., primary, Aminoff, Michael J., additional, Beall, Marie H., additional, Benirschke, Kurt, additional, Blanchard, Daniel G., additional, Blum, Kristie, additional, Catalano, Patrick, additional, Chambers, Christina, additional, Clyman, Ronald, additional, Cohn, David, additional, Creasy, Robert K., additional, D'Alton, Mary E., additional, Davison, John M., additional, Deprest, Jan A., additional, Dombrowski, Mitchell P., additional, Donovan, Edward F., additional, Duff, Patrick, additional, Edwards, Rodney K., additional, Erkan, Doruk, additional, Fineman, Jeffrey R., additional, Foley, Michael Raymond, additional, Funai, Edmund F., additional, Gagnon, Robert, additional, Ghidini, Alessandro, additional, Gilstrap, Larry C., additional, Gratacos, Eduardo, additional, Greenberg, James M., additional, Haberman, Beth, additional, Hamilton, Bruce A., additional, Hanson, Mark, additional, Harman, Christopher R., additional, Hossain, Nazli, additional, Hull, Andrew D., additional, Iams, Jay D., additional, Jenkins, Thomas M., additional, Jobe, Alan H., additional, Kelly, Thomas F., additional, Khalek, Nahla, additional, Kilpatrick, Sarah J., additional, Kuczkowski, Krzysztof M., additional, Lawrence, Robert M., additional, Lawrence, Ruth A., additional, Lewi, Liesbeth, additional, Liu, James H., additional, Lockshin, Michael D., additional, Lockwood, Charles J., additional, Lye, Stephen J., additional, Mackillop, Lucy, additional, Macones, George A., additional, Malone, Fergal D., additional, Manning, Frank A., additional, Martin, Stephanie Rae, additional, Mercer, Brian M., additional, Meschia, Giacomo, additional, Moise, Kenneth J., additional, Monga, Manju, additional, Moore, Thomas R., additional, Mor, Gil, additional, Nader, Shahla, additional, Nageotte, Michael P., additional, Narendran, Vivek, additional, Norwitz, Errol R., additional, Paidas, Michael J., additional, Poston, Lucilla, additional, Ramaswamy, Bhuvaneswari, additional, Rapini, Ronald P., additional, Resnik, Jamie L., additional, Resnik, Robert, additional, Richardson, Bryan S., additional, Roberts, James M., additional, Romero, Roberto, additional, Ross, Michael G., additional, Salmon, Jane E., additional, Savides, Thomas J., additional, Schibler, Kurt R., additional, Shabetai, Ralph, additional, Silver, Robert M., additional, Sklansky, Mark, additional, Stotland, Naomi E., additional, Sweet, Richard L., additional, Thorp, John M., additional, Vergani, Patrizia, additional, Wapner, Ronald J., additional, Warner, Barbara B., additional, Weiner, Carl P., additional, Whitty, Janice E., additional, Wilkins, Isabelle, additional, Williams, David J., additional, Williamson, Catherine, additional, Wynshaw-Boris, Anthony, additional, and Yonkers, Kimberly A., additional

Published
2009
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235. 186 Cesarean hysterectomy for placenta accreta spectrum: comparison of two management strategies

Author

Mourad, Mirella, primary, Breslin, Noelle, additional, Syeda, Sbaa K., additional, Moroz, Leslie, additional, Nhan-Chang, Chia-Ling, additional, Booker, Whitney A., additional, Laifer-Narin, Sherelle, additional, Ring, Laurence, additional, Smiley, Richard, additional, Cimic, Adela, additional, Huang, Yongmei, additional, St. Clair, Caryn, additional, Melamed, Alexander, additional, Wright, Jason D., additional, D'Alton, Mary E., additional, and Collado, Fady Khoury, additional

Published
2021
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241. 953 Risk of cervical shortening and spontaneous preterm births during the COVID19 pandemic

Author

Ona, Samsiya, primary, Krenitsky, Nicole, additional, Chen, Cheng, additional, Hairston, Jacqueline, additional, Reed-Weston, Anne E., additional, Polin, Melanie, additional, Arditi, Brittany, additional, Vink, Joy-Sarah, additional, Mourad, Mirella, additional, Coletta, Jaclyn L., additional, Turitz, Amy, additional, Goffman, Dena, additional, D'Alton, Mary E., additional, and Gyamfi-Bannerman, Cynthia, additional

Published
2021
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246. Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City

Author

Dumitriu, Dani, primary, Emeruwa, Ukachi N., additional, Hanft, Erin, additional, Liao, Grace V., additional, Ludwig, Elizabeth, additional, Walzer, Lauren, additional, Arditi, Brittany, additional, Saslaw, Minna, additional, Andrikopoulou, Maria, additional, Scripps, Tessa, additional, Baptiste, Caitlin, additional, Khan, Adrita, additional, Breslin, Noelle, additional, Rubenstein, David, additional, Simpson, Lynn L., additional, Kyle, Margaret H., additional, Friedman, Alexander M., additional, Hirsch, Daniel S., additional, Miller, Russell S., additional, Fernández, Cristina R., additional, Fuchs, Karin M., additional, Keown, M. Kathleen, additional, Glassman, Melissa E., additional, Stephens, Ashley, additional, Gupta, Archana, additional, Sultan, Sally, additional, Sibblies, Caroline, additional, Whittier, Susan, additional, Abreu, Wanda, additional, Akita, Francis, additional, Penn, Anna, additional, D’Alton, Mary E., additional, Orange, Jordan S., additional, Goffman, Dena, additional, Saiman, Lisa, additional, Stockwell, Melissa S., additional, and Gyamfi-Bannerman, Cynthia, additional

Published
2021
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248. Nutrition during Pregnancy: Findings from the National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies–Singleton Cohort

Author

Hinkle, Stefanie N, primary, Zhang, Cuilin, additional, Grantz, Katherine L, additional, Sciscione, Anthony, additional, Wing, Deborah A, additional, Grobman, William A, additional, Newman, Roger B, additional, D’Alton, Mary E, additional, Skupski, Daniel, additional, Nageotte, Michael P, additional, Ranzini, Angela C, additional, Owen, John, additional, Chein, Edward K, additional, Craigo, Sabrina, additional, Yisahak, Samrawit F, additional, Liu, Aiyi, additional, Albert, Paul S, additional, Louis, Germaine M Buck, additional, and Grewal, Jagteshwar, additional

Published
2021
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