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New research, 'Cloning and expression of medaka cholesterol side chain cleavage cytochrome P450 during gonadal development,' is the subject of a report. 'Cholesterol side chain cleavage cytochrome P450 (P450scc, Cyp11a) [...]

Investigators publish new data in the report 'Insulin-like growth factor-I activates extracellularly regulated kinase to regulate the p450 side-chain cleavage insulin-like response element in granulosa cells.' According to recent research [...]

'Ethanol neurobehavioural teratogenicity is a leading cause of developmental mental deficiency, in which the hippocampus is a target site of injury. The multi-faceted mechanism of ethanol teratogenicity is not completely [...]

A new study, 'Up-regulation of human CYP2J2 in HepG2 cells by butylated hydroxyanisole is mediated by c-Jun and Nrf2,' is now available. According to recent research from Australia, 'Cytochrome P450 [...]

Scientists discuss in 'Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450' new findings in life sciences. 'Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty [...]

Current study results from the report, 'Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3,' have been [...]

Fresh data on life sciences are presented in the report 'Novel application of 2D and 3D-similarity searches to identify substrates among cytochrome P450 2C9, 2D6, and 3A4.' According to recent [...]

A new study, 'Human cytochrome P450 oxidoreductase deficiency caused by the Y181D mutation: molecular consequences and rescue of defect,' is now available. According to recent research from the United States, [...]

'Interactions of acutely administered grapefruit juice (GFJ) with cytochrome P450 isoform 3A4 (CYP3A4) and P-glycoprotein (Pgp) function are well established. In this study, we investigated in vitro the effect of [...]

'The aryl hydrocarbon receptor (AhR), a client protein of heat shock protein 90 (HSP90), plays a significant role in polycyclic aromatic hydrocarbon (PAH)-induced carcinogenesis. Tobacco smoke, a source of PAHs, [...]

According to recent research published in the journal Hepatology Research, 'The curative effect of emodin (1,3,8-trihydroxy-6-methyl anthraquinone), an active compound of the plant species Ventilago maderaspatana Gaertn, was evaluated against [...]

'CYP1A1 and CYP1B1, members of the cytochrome P450 protein family, are regulated by fluid shear stress. This study describes the effects of duration, magnitude and pattern of shear stress on [...]

A report, 'Coplanar polychlorinated biphenyl-induced CYP1A1 is regulated through caveolae signaling in vascular endothelial cells,' is newly published data in Chemico-Biological Interactions. According to recent research from the United States, [...]

Investigators publish new data in the report 'Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling.' [...]

Investigators publish new data in the report 'Association study of the cytochrome P450 17 gene polymorphism with personality traits in healthy subjects.' 'There have been several studies suggesting that sex [...]

Research findings, 'Role of C-terminal sequence of cytochrome P450scc in folding and functional activity,' are discussed in a new report. In this recent study, researchers in Minsk, Belarus conducted a [...]

Cardiovascular data are the focus of recent research from Canada and the United States. Study 1: Cytochrome p450 2C inhibition reduces post-ischemic vascular dysfunction. According to a report from Canada, [...]