988 results on '"Clarke, David M."'
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202. Introduction of the Most Common Cystic Fibrosis Mutation (ΔF508) into Human P-glycoprotein Disrupts Packing of the Transmembrane Segments
203. Talking About Safety—An Interview with Trevor Kletz, Part 2: Hazop, Hazan and the Attitude of the Public to Technological Risk
204. Application of Chemical Chaperones to the Rescue of Folding Defects.
205. Letters to the Editor
206. Determining the Dimensions of the Drug-binding Domain of Human P-glycoprotein Using Thiol Cross-linking Compounds as Molecular Rulers
207. Talking About Safety—An Interview with Trevor Kletz, Part 1: Inherently Safer Design
208. Cross-linking of Human Multidrug Resistance P-glycoprotein by the Substrate, Tris-(2-maleimidoethyl)amine, Is Altered by ATP Hydrolysis
209. Defining the Drug-binding Site in the Human Multidrug Resistance P-glycoprotein Using a Methanethiosulfonate Analog of Verapamil, MTS-verapamil
210. Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane
211. Drug-stimulated ATPase Activity of Human P-glycoprotein Is Blocked by Disulfide Cross-linking between the Nucleotide-binding Sites
212. The Packing of the Transmembrane Segments of Human Multidrug Resistance P-glycoprotein Is Revealed by Disulfide Cross-linking Analysis
213. Location of high affinity Ca2-binding sites within the predicted transmembrane domain of the sarcoplasmic reticulum CA2-ATPase
214. Identification of Residues in the Drug-binding Domain of Human P-glycoprotein
215. Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques
216. The Transmembrane Domains of the Human Multidrug Resistance P-glycoprotein Are Sufficient to Mediate Drug Binding and Trafficking to the Cell Surface
217. Sex, Honesty and the Supervisory Relationship: a Response to Ryan
218. Measuring the Quality of Supervision and the Training Experience in Psychiatry
219. Psychological morbidity and quality of life in Australian women with early‐stage breast cancer: a cross‐sectional survey: In reply
220. How is Psychiatry Taught to Australian and New Zealand Medical Students?
221. Quality Control by Proteases in the Endoplasmic Reticulum
222. Modelling the frequency of psychiatric admissions
223. Monash Interview for Liaison Psychiatry (MILP) Development, Reliability, and Procedural Validity
224. Nonylphenol Ethoxylates, but Not Nonylphenol, Are Substrates of the Human Multidrug Resistance P-glycoprotein
225. Superfolding of the Partially Unfolded Core-glycosylated Intermediate of Human P-glycoprotein into the Mature Enzyme Is Promoted by Substrate-induced Transmembrane Domain Interactions
226. Consultation-Liaison Psychiatrists’ Management of Depression
227. Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate
228. Learning Safety Lessons from Mistakes: The Role of Trust
229. Drug-stimulated ATPase Activity of Human P-glycoprotein Requires Movement between Transmembrane Segments 6 and 12
230. Accurate confidence intervals for measures of test performance
231. Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators
232. Cytoplasmic Loop Three of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Regulation of Chloride Channel Activity
233. Comparing correlated kappas by resampling: Is one level of agreement significantly different from another?
234. Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates
235. The Minimum Functional Unit of Human P-glycoprotein Appears to be a Monomer
236. Mutational Analysis of the Predicted First Transmembrane Segment of Each Homologous Half of Human P-glycoprotein Suggests That They Are Symmetrically Arranged in the Membrane
237. Disease-associated Mutations in the Fourth Cytoplasmic Loop of Cystic Fibrosis Transmembrane Conductance Regulator Compromise Biosynthetic Processing and Chloride Channel Activity
238. Recognising drug and alcohol problems in patients referred to consultation‐liaison psychiatry
239. Rapid Purification of Human P-glycoprotein Mutants Expressed Transiently in HEK 293 Cells by Nickel-Chelate Chromatography and Characterization of their Drug-stimulated ATPase Activities
240. P-glycoprotein
241. Covalent Modification of Human P-glycoprotein Mutants Containing a Single Cysteine in Either Nucleotide-binding Fold Abolishes Drug-stimulated ATPase Activity
242. Consultation-Liaison Psychiatry in General Medical Units
243. Expression of a Functionally Active Human Renal Sodium-Calcium Exchanger Lacking a Signal Sequence
244. The recognition of depression in patients referred to a consultation-liaison service
245. Membrane Topology of a Cysteine-less Mutant of Human P-glycoprotein
246. Mutations to Amino Acids Located in Predicted Transmembrane Segment 6 (TM6) Modulate the Activity and Substrate Specificity of Human P-glycoprotein
247. Psychiatric disorders in and service use by young homeless people
248. A caution on the use of cut-points applied to screening instruments or diagnostic criteria
249. Learning approaches as a predictor of examination results in pre-clinical medical students
250. Psychosocial treatment approaches to difficult‐to‐treat depression.
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