96,939 results on '"Carles A"'
Search Results
202. Biomarkers of axonal damage to favor early diagnosis in variant transthyretin amyloidosis (A-ATTRv)
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González-Moreno, Juan, Gragera-Martínez, Álvaro, Rodríguez, Adrián, Borrachero-Garro, Cristina, García-Garrido, Sandra, Barceló, Carles, Manovel-Sánchez, Ana, Ribot-Sansó, Maria Antonia, Ibargüen-González, Lesly, Gomila, Rosa, Muñoz-Beamud, Francisco, Losada-López, Inés, and Cisneros-Barroso, Eugenia
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- 2024
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203. Non-drinking and social life in adolescence: a qualitative study in Switzerland
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Lorraine Chok, Joan-Carles Suris, Lucie Vittoz, Diana Fernandes Palhares, and Yara Barrense-Dias
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Abstinence ,Alcohol consumption ,Non-drinkers ,Social life ,Youth ,Public aspects of medicine ,RA1-1270 ,Social Sciences - Abstract
Abstract Background Alcohol consumption is popular among adolescents and young people and adolescent non-drinkers may be socially excluded and/or stigmatized. The aim of this qualitative study was to explore the social life of young non-drinkers (14–20 years old), to understand how they live their non-drinking and how they are perceived by their drinking peers. Methods We conducted a qualitative research on non-consumption of alcohol in the French-speaking region of Switzerland. Our study included 63 young people divided into 12 focus groups aged 14 to 20 years. Results Overall, young non-drinkers would be a minority in their peer groups, leading some of them to feel out of the norm. Participants reported that not drinking alcohol is generally questioned and non-drinkers are almost always asked to justify their non-consumption. Finally, non-drinkers are sometimes automatically designated as resources who have to control the drinking of others and/or are the ones who help their drinking-peers if they are drunk and need help, a status that can put them under pressure. Conclusions It is important to normalize the non-consumption of alcohol and make non-drinkers visible by including them in school-based prevention interventions.
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- 2024
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204. Propiedades psicométricas de la Escala Gencat de Calidad de Vida en una muestra de personas sin hogar
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Eva María BENITO HERRÁEZ, Carles ALSINET MORA, and Araceli MACIÁ ANTÓN
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calidad de vida ,personas sin hogar ,teoría de respuesta al ítem ,Psychology ,BF1-990 ,Vocational rehabilitation. Employment of people with disabilities ,HD7255-7256 ,Social sciences (General) ,H1-99 - Abstract
El objetivo principal de esta investigación es analizar las propiedades psicométricas de la Escala Gencat de Calidad de Vida en una muestra de 72 personas usuarias de la Oficina Municipal de Atención para Personas en Situación de sin Hogar de la ciudad de Lleida. El análisis de los 69 ítems se ha basado en la Teoría Clásica de los Test y en la Teoría de Respuesta al Ítem. Los resultados del alfa de Cronbach muestran valores adecuados, situándose entre .749 y .853. Según el modelo de Escalas de Clasificación la confiabilidad es alta con valores superiores a .95 en todas las dimensiones. La mayoría de ítems se ajusta al modelo. La limitación más importante del estudio es el tamaño de la muestra, que disminuye su confiabilidad. A pesar de ello se puede concluir que la escala posee evidencias suficientes de fiabilidad para poder evaluar la calidad de vida de las personas sin hogar.
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- 2016
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205. La participación del alumnado en la vida del centro: una aproximación desde la comunidad educativa
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Carles ALSINET MORA, Aida URREA MONCLÚS, Ignacio GUADIX GARCÍA, and Oscar BELMONTE CASTELL
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participación infantil ,experiencias escolares ,Convención de los Derechos del Niño ,ciudadanía. ,Education ,Education (General) ,L7-991 - Abstract
La Convención de los Derechos del Niño (CDN, 1989) es actualmente el tratado internacional más ratificado. Distintos autores han puesto de relieve su potencialidad para una educación moral y en la ciudadanía. Aun así, paradójicamente, distintas investigaciones informan de su incorporación escasa u ocasional en las prácticas escolares. En este artículo se realiza una aproximación a las experiencias escolares sobre participación, la tercera P de la CDN, desde la pluralidad de voces y actores de la comunidad educativa, mediante 14 grupos de discusión en 11 comunidades autónomas del estado español. El análisis de los discursos evidencia bajos niveles de participación del alumnado en la vida escolar. Pero, a la vez, se constata un escenario educativo propicio para el desarrollo de proyectos que contribuyan a la participación infantil, así como a la incorporación de la CDN como elemento motor de la vida del centro y referente integrador de los distintos proyectos de centro.
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- 2016
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206. FACTORES ASOCIADOS AL SOBREPESO Y LA OBESIDAD EN ESCOLARES DE 8 A 9 AÑOS DE BARCELONA
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Francesca Sánchez-Martínez, Peter Torres Capcha, Gemma Serral Cano, Sara Valmayor Safont, Conxa Castell Abat, Carles Ariza Cardenal, and Grupo de Evaluación del Proyecto POIBA.
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Medicine ,Public aspects of medicine ,RA1-1270 - Abstract
Fundamentos: El sobrepeso y la obesidad infantil han aumentado progresivamente en las últimas décadas, especialmente en países del sur de Europa. El objetivo del estudio fue identificar la prevalencia de sobrepeso, obesidad y sus determinantes en escolares de 8-9 años de Barcelona. Métodos: Estudio transversal descriptivo de una muestra representativa de 3.262 escolares en 2011. Se calculó el Índice de Masa Corporal (IMC) siguiendo los criterios establecidos por la Organización Mundial de la Salud (z-scores). Se estudiaron variables sobre conducta alimentaria, actividad física y uso de nuevas tecnologías mediante 2 cuestionarios. Se ajustaron modelos de regresión logística, obteniendo odds ratio ajustadas e intervalos de confianza (95%). Resultados: La prevalencia de sobrepeso fue del 24,0% y de obesidad del 12,7%. La obesidad fue significativamente mayor en niños que en niñas (14,8% vs. 10,8%). No se observaron diferencias estadísticamente significativas según IMC en el cumplimiento de las recomendaciones de práctica de actividad física ni uso de nuevas tecnologías. Los factores asociados a la obesidad en niños fueron asistir a escuela situada en barrios de nivel socioeconómico desfavorable [ORa=1,88 (1,35-2,63)], pertenecer a familia inmigrante [ORa=1,57 (1,12- 2,20)], no comer en el colegio [ORa=1,76 (1,20-2,59)] y hacer alguna comida solo [ORa=1,95 (1,27-3,00)]. En niñas fueron pertenecer a familia monoparental [ORa=1,58 (1,06-2,34)] y familia inmigrante [ORa=1,53 (1,07-2,18)]. Conclusiones: La prevalencia de obesidad infantil en Barcelona es alta. Es más frecuente en niños, siendo los determinantes sociales los factores asociados de mayor relevancia.
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- 2016
207. Lexical Transfer as a Resource in Pedagogical Translanguaging
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Carles Fuster
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'Translanguaging' has become the most popular term in discussions about how to use learners' languages as resources for target language teaching/learning, but it has also become ambiguous because it is being developed in proposals adopting different perspectives on multilingualism. The first aim of this article is to offer an overview of the two main current proposals of translanguaging together: García and colleagues' 'spontaneous translanguaging' and Cenoz and Gorter's 'pedagogical translanguaging'. 'Spontaneous translanguaging' argues that languages in the mind are represented as one single system and that the notion of transfer, consequently, must be rejected. This article argues that this view may not be practical because it makes it difficult for teachers to conceptualise what they are doing when raising awareness of similarities between learners' languages. 'Pedagogical translanguaging', by contrast, centres around transfer. Whereas transfer is traditionally seen as unintentional 'interference', pedagogical translanguaging considers it a phenomenon that learners can use intentionally and creatively, and which teachers could promote by raising learners' awareness of similarities between their languages. However, very little is known about how learners use transfer unintentionally versus intentionally. This article discusses key findings and implications from Fuster's (2022) initial study on intentionality in lexical transfer within pedagogical translanguaging.
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- 2024
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208. Small RNAs Virome Characterization Reveals Arthropod-Associated Viruses in Anopheles atroparvus from the Ebro Delta, Spain
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Lotty Birnberg, Francisco M. Codoñer, Raúl Escosa, Carles Aranda, Ana Isabel Núñez, Sandra Talavera, and Núria Busquets
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Anopheles atroparvus ,small RNA ,Chaq virus ,Partiti-like viruses ,arthropod ,viruses ,General Works - Abstract
Even though malaria was eradicated from Europe after the mid-20th century, in 2017, more than 8000 imported cases were reported in the continent. Due to travel routes to endemic areas, climate change, and the presence of native vector mosquitoes (genus Anopheles), the re-establishment of autochthonous malaria transmission is a current concern. Anopheles atroparvus (Van Thiel, 1972) is one of the 11 sibling species within the Palearctic Anopheles maculipennis complex, which formerly were considered the main vectors of the disease in the European continent. The microbiota (bacteria and viruses) of vector species has been demonstrated to play a significant role in the biology of these organisms, including their infection susceptibility and their capacity to transmit disease-causing agents. Recently, with the improvement of metagenomics techniques, several viruses that naturally infect vector mosquitoes have been identified. The purpose of the present study was to characterize, for the first time, the virome present in An. atroparvus from the Ebro Delta and assess its evolution after ten generations in the laboratory. Small RNA sequencing was used to characterize the virome from wild-caught An. atroparvus females and from the tenth generation produced under controlled laboratory conditions. Through this approach, we were able to identify viral linages previously reported in other invertebrates, such as Chaq virus and several Partiti-like viruses. A reduction in the viral composition was observed during the colonization process. The present study contributes to the understanding of the viral diversity of a medically relevant vector species in its natural setting and under confinement, and sets a baseline for further studies to assess the potential implications of these viruses in the transmission of pathogens.
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- 2020
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209. Viromics on Honey-Baited FTA Cards as a New Tool for the Detection of Circulating Viruses in Mosquitoes
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Lotty Birnberg, Sarah Temmam, Carles Aranda, Florencia Correa-Fiz, Sandra Talavera, Thomas Bigot, Marc Eloit, and Núria Busquets
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fta cards ,ngs ,insect specific virus ,saliva ,alphamesonivirus ,quaranjavirus ,unclassified bunyavirales ,Microbiology ,QR1-502 - Abstract
Worldwide, emerging and re-emerging infectious diseases (EIDs) are a major burden on public and animal health. Arthropod vectors, with mosquitoes being the main contributors of global disease, transmit more than 70% of the recognized EIDs. To assess new alternatives for arthropod-borne viral diseases surveillance, and for the detection of new viruses, honey-baited Flinders Technology Associates (FTA) cards were used as sugar bait in mosquito traps during entomological surveys at the Llobregat River Delta (Catalonia, Spain). Next generation sequencing (NGS) metagenomics analysis was applied on honey-baited FTA cards, which had been exposed to field-captured mosquitoes to characterize their associated virome. Arthropod- and plant-infecting viruses governed the virome profile on FTA cards. Twelve near-complete viral genomes were successfully obtained, suggesting good quality preservation of viral RNAs. Mosquito pools linked to the FTA cards were screened for the detection of mosquito-associated viruses by specific RT-PCRs to confirm the presence of these viruses. The circulation of viruses related to Alphamesonivirus, Quaranjavirus and unclassified Bunyavirales was detected in mosquitoes, and phylogenetic analyses revealed their similarities to viruses previously reported in other continents. To the best our knowledge, our findings constitute the first distribution record of these viruses in European mosquitoes and the first hint of insect-specific viruses in mosquitoes’ saliva in field conditions, demonstrating the feasibility of this approach to monitor the transmissible fraction of the mosquitoes’ virome. In conclusion, this pilot viromics study on honey-baited FTA cards was shown to be a valid approach for the detection of viruses circulating in mosquitoes, thereby setting up an alternative tool for arbovirus surveillance and control programs.
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- 2020
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210. Movements and dispersal of brown trout (Salmo trutta Linnaeus, 1758) in Mediterranean streams: influence of habitat and biotic factors
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Enric Aparicio, Rafel Rocaspana, Adolfo de Sostoa, Antoni Palau-Ibars, and Carles Alcaraz
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River connectivity ,Headwaters ,Mark-recapture ,Salmonidae ,Management ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Dispersal is a critical determinant of animal distribution and population dynamics, and is essential information for management planning. We studied the movement patterns and the influence of habitat and biotic factors on Mediterranean brown trout (Salmo trutta) by mark-recapture methods in three headwater streams of the Ebro Basin (NE Iberian Peninsula). Fish were sampled by electrofishing on five occasions over 18–24 months and movements of over 3,000 individually tagged trout (age 1+ onwards) were recorded. Most of the tagged fish exhibited limited movement and were recaptured within 100 m from the initial capture section. Small seasonal differences in the movement pattern were observed, but in two of the streams, displacement distances increased prior the spawning period in autumn. The frequency distributions of dispersal distances were highly leptokurtic and skewed to the right and fitted well to a two-group exponential model, thus trout populations were composed of mobile and stationary individuals, the latter being the predominant component in the populations (71.1–87.5% of individuals). The mean dispersal distances, for fish captured at least in three sampling events, ranged 20.7–45.4 m for the stationary group and 229.4–540.5 m for the mobile group. Moving brown trout were larger than non-moving individuals and exhibited higher growth rates in two of the streams. Habitat features were not consistently linked to movement rates, but there were some interaction effects between stream and habitat characteristics such as depth, cover and water velocity.
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- 2018
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211. Derechos de la Infancia y Ciudadanía Global: una aproximación desde la comunidad educativa
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Aida Urrea Monclús, Jordi L. Coiduras Rodríguez, Carles Alsinet Mora, M. Àngels Balsells Bailón, Ignacio Guadix García, and Oscar Belmonte Castell
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derechos de la infancia ,ciudadanía global ,comunidad educativa ,enfoque de derechos ,participación infantil ,Sociology (General) ,HM401-1281 - Abstract
La Convención de los Derechos del Niño (CDN) es una herramienta fundamental para la educación de niños, niñas y adolescentes. Ésta debe entenderse como el marco de referencia universal que contribuye a formar niños y niñas capacitados para ejercer sus derechos de ciudadanía. Sin embargo, conocemos muy poco sobre cómo los derechos de la infancia y la ciudadanía global se integran en el sistema educativo español. El objetivo de este trabajo es identificar las necesidades formativas que tiene la comunidad educativa en relación a la CDN desde las dimensiones cognitiva, metodológica y actitudinal. Se trata de una investigación cualitativa que ha contado con la participación de 124 personas representantes de la comunidad educativa (alumnado, docentes, padres y madres) distribuidas en 14 grupos de discusión desarrollados en 11 Comunidades Autónomas del territorio español. El análisis de contenido muestra la escasa incorporación en los centros escolares de la CDN, así como una la visión parcial de ésta por parte de los integrantes de la comunidad educativa. Se observan necesidades en la falta de estrategias de enseñanza-aprendizaje que fomenten la autonomía y la participación infantil en el aula y el centro. Finalmente, se observa la dificultad de posicionar a la infancia como sujeto de derechos con facultades para ejercer su ciudadanía.
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- 2018
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212. A childhood obesity prevention programme in Barcelona (POIBA Project): Study protocol of the intervention
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Francesca Sánchez-Martínez, Olga Juárez, Gemma Serral, Sara Valmayor, Rosa Puigpinós, María Isabel Pasarín, Élia Díez, Carles Ariza, and Evaluation Group POIBA Project
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School-based intervention programme ,Evaluation ,Lifestyle ,Eating habits ,Physical activity ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Childhood obesity preventive interventions should promote a healthy diet and physical activity at home and school. This study aims to describe a school-based childhood obesity preventive programme (POIBA Project) targeting 8-to-12- year-old. Design and methods: Evaluation study of a school-based intervention with a pre-post quasi-experimental design and a comparison group. Schools from disadvantaged neighbourhoods are oversampled. The intervention consists of 9 sessions, including 58 activities of a total duration between 9 and 13 hours, and the booster intervention of 2 sessions with 8 activities lasting 3 or 4 hours. They are multilevel (individual, family and school) and multicomponent (classroom, physical activity and family). Data are collected through anthropometric measurements, physical fitness tests and lifestyle surveys before and after the intervention and the booster intervention. In the intervention group, families complete two questionnaires about their children’s eating habits and physical activity. The outcome variable is the cumulative incidence rate of obesity, obtained from body mass index values and body fat assessed by triceps skinfold thickness. The independent variables are socio-demographic, contextual, eating habits, food frequency, intensity of physical activity and use of new technologies. Expected impact for public health: It is essential to implement preventive interventions at early ages and to follow its effects over time. Interventions involving diet and physical activity are the most common, being the most effective setting the school. The POIBA Project intervenes in both the school and family setting and focuses on the most disadvantaged groups, in which obesity is most pronounced and difficult to prevent.
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- 2018
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213. Social Democracy and the Birth of Working-Class Representation in Europe
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Mor, Maayan and Boix, Carles
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- 2024
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214. Allogeneic hematopoietic cell transplantation with sequential conditioning regimen in relapsed refractory acute myeloid leukemia
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Tolosa-Ridao, Carles, Suárez-Lledó, María, Jiménez-Vicente, Carlos, Cortés-Bullich, Albert, Merchan, Beatriz, Martínez-Roca, Alexandra, Guijarro, Francisca, Castaño-Díez, Sandra, Rosiñol, Laura, Fernández-Avilés, Francesc, Martínez, Carmen, Díaz-Beya, Marina, Esteve, Jordi, Rovira, Montserrat, and Salas, María Queralt
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- 2024
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215. Effects of enhanced hydrological connectivity on Mediterranean salt marsh fish assemblages with emphasis on the endangered Spanish toothcarp (Aphanius iberus)
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Patricia Prado, Carles Alcaraz, Lluis Jornet, Nuno Caiola, and Carles Ibáñez
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Distance to the sea ,Connectivity ,Isolation ,Salt marsh rehabilitation ,Fish diversity ,Aphanius iberus ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
The hydrological connectivity between the salt marsh and the sea was partially restored in a Mediterranean wetland containing isolated ponds resulting from former salt extraction and aquaculture activities. A preliminary assessment provided evidence that ponds farther from the sea hosted very large numbers of the endangered Spanish toothcarp, Aphanius iberus, suggesting that individuals had been trapped and consequently reach unnaturally high densities. In order to achieve both habitat rehabilitation and toothcarp conservation, efforts were made to create a gradient of hydrologically connected areas, including isolated fish reservoirs, semi-isolated, and connected salt marsh-sea areas that could allow migratory movements of fish and provide some protection for A. iberus. The fish community was monitored prior to, and for three years after rehabilitation. Results showed an increase in the number of fish species within semi-isolated areas (Zone A), whereas areas adjacent to the sea (Zone B) increased the number of marine species and decreased that of estuarine species (ES). Yet overall differences in fish assemblages were much higher between zones than among study years. Generalized linear models (GLMs) evidenced that distance to the sea was the most important variable explaining the local diversity of the fish community after restoration, with occasional influence of other factors such as temperature, and depth. The abundance of A. iberus was consistently higher in semi-isolated areas at greater distances from the sea, but a decline occurred in both zones and in isolated reservoir ponds after restoration efforts, which may be attributable to interannual differences in recruitment success and, to a lesser extent, to dispersal into adjacent habitats. A negative effect of restoration works on fish population cannot be excluded, but the final outcome of the intervention likely needs a longer period.
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- 2017
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216. Structural identifiability analysis of linear reaction-advection-diffusion processes in mathematical biology
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Browning, Alexander P, Tască, Maria, Falcó, Carles, and Baker, Ruth E
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Quantitative Biology - Quantitative Methods ,Statistics - Methodology ,12H05, 35A24, 35Q92, 62F99 - Abstract
Effective application of mathematical models to interpret biological data and make accurate predictions often requires that model parameters are identifiable. Approaches to assess the so-called structural identifiability of models are well-established for ordinary differential equation models, yet there are no commonly adopted approaches that can be applied to assess the structural identifiability of the partial differential equation (PDE) models that are requisite to capture spatial features inherent to many phenomena. The differential algebra approach to structural identifiability has recently been demonstrated to be applicable to several specific PDE models. In this brief article, we present general methodology for performing structural identifiability analysis on partially observed reaction-advection-diffusion (RAD) PDE models that are linear in the unobserved quantities. We show that the differential algebra approach can always, in theory, be applied to such models. Moreover, despite the perceived complexity introduced by the addition of advection and diffusion terms, identifiability of spatial analogues of non-spatial models cannot decrease in structural identifiability. We conclude by discussing future possibilities and the computational cost of performing structural identifiability analysis on more general PDE models.
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- 2023
217. Recovering lost light: discovery of supernova remnants with integral field spectroscopy
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Martínez-Rodríguez, Héctor, Galbany, Lluís, Badenes, Carles, Anderson, Joseph P., Domínguez, Inmaculada, Kuncarayakti, Hanindyo, Lyman, Joseph D., Sánchez, Sebastián F., Vílchez, José M., Smith, Nathan, and Milisavljevic, Dan
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present results from a systematic search for broad ($\geq$ 400 \kms) \ha\ emission in Integral Field Spectroscopy data cubes of $\sim$1200 nearby galaxies obtained with PMAS and MUSE. We found 19 unique regions that pass our quality cuts, four of which match the locations of previously discovered SNe: one Type IIP, and three Type IIn, including the well-known SN 2005ip. We suggest that these objects are young Supernova Remnants, with bright and broad \ha\ emission powered by the interaction between the SN ejecta and dense circumstellar material. The stellar ages measured at the location of these SNR candidates are systematically lower by about 0.5 dex than those measured at the location of core collapse SNe, implying that their progenitors might be shorter lived and therefore more massive than a typical CC SN progenitor. The methods laid out in this work open a new window into the study of nearby SNe with Integral Field Spectroscopy., Comment: 16 pages, 10 figures, replaced with accepted version on 01/05/2024
- Published
- 2023
218. Leveraging Diversity in Online Interactions
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Osman, Nardine, Gui, Bruno Rosell i, and Sierra, Carles
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Computer Science - Artificial Intelligence ,68T01 ,H.0 - Abstract
This paper addresses the issue of connecting people online to help them find support with their day-to-day problems. We make use of declarative norms for mediating online interactions, and we specifically focus on the issue of leveraging diversity when connecting people. We run pilots at different university sites, and the results show relative success in the diversity of the selected profiles, backed by high user satisfaction.
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- 2023
219. On nonlinear effects in multiphase WKB analysis for the nonlinear Schrodinger equation
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Carles, Remi
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Mathematics - Analysis of PDEs ,Mathematical Physics - Abstract
We consider the Schrodinger equation with an external potential and a cubic nonlinearity, in the semiclassical limit. The initial data are sums of WKB states, with smooth phases and smooth, compactly supported initial amplitudes, with disjoint supports. We show that like in the linear case, a superposition principle holds on some time interval independent of the semiclassical parameter, in several regimes in term of the size of initial data with respect to the semiclassical parameter. For large data, we invoke properties of compressible Euler equations. For smaller data, we show that there may be no nonlinear interferences on some time interval independent of the semiclassical parameter, and interferences for later time, thanks to explicit computations available for particular phases., Comment: The version was uploaded on Hal on November 29, but failed to be forwarded to arXiv. Restatement of the main results (abstract changed), more explanations, generalized setting
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- 2023
220. Do Type Ia Supernovae Explode Inside Planetary Nebulae?
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Court, Travis, Badenes, Carles, Lee, Shiu-Hang, Patnaude, Daniel, García-Segura, Guillermo, and Bravo, Eduardo
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The nature of Type Ia Supernova (SN Ia) explosions remains an open issue, with several contending progenitor scenarios actively being considered. One such scenario involves a SN Ia explosion inside a planetary nebula (PN) in the aftermath of a stellar merger triggered by a common envelope (CE) episode. We examine this scenario using hydrodynamic and non-equilibrium ionization simulations of the interaction between the SN ejecta and the PN cocoon into the supernova remnant (SNR) phase, focusing on the impact of the delay between the CE episode and the SN explosion. We compare the bulk dynamics and X-ray spectra of our simulated SNRs to the observed properties of known Type Ia SNRs in the Milky Way and the Magellanic Clouds. We conclude that models where the SN explosion happens in the immediate aftermath of the CE episode (with a delay $\lesssim$1,000 yr) are hard to reconcile with the observations, because the interaction with the dense PN cocoon results in ionization timescales much higher than those found in any known Type Ia SNR. Models with a longer delay between the CE episode and the SN explosion ($\sim$10,000 yr) are closer to the observations, and may be able to explain the bulk properties of some Type Ia SNRs., Comment: 9 pages, 5 figures
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- 2023
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221. Ground-based and JWST Observations of SN 2022pul: I. Unusual Signatures of Carbon, Oxygen, and Circumstellar Interaction in a Peculiar Type Ia Supernova
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Siebert, Matthew R., Kwok, Lindsey A., Johansson, Joel, Jha, Saurabh W., Blondin, Stéphane, Dessart, Luc, Foley, Ryan J., Hillier, D. John, Larison, Conor, Pakmor, Rüdiger, Temim, Tea, Andrews, Jennifer E., Auchettl, Katie, Badenes, Carles, Barna, Barnabas, Bostroem, K. Azalee, Newman, Max J. Brenner, Brink, Thomas G., Bustamante-Rosell, María José, Camacho-Neves, Yssavo, Clocchiatti, Alejandro, Coulter, David A., Davis, Kyle W., Deckers, Maxime, Dimitriadis, Georgios, Dong, Yize, Farah, Joseph, Filippenko, Alexei V., Flörs, Andreas, Fox, Ori D., Garnavich, Peter, Gonzalez, Estefania Padilla, Graur, Or, Hambsch, Franz-Josef, Hosseinzadeh, Griffin, Howell, D. Andrew, Hughes, John P., Kerzendorf, Wolfgang E., Saux, Xavier K. Le, Maeda, Keiichi, Maguire, Kate, McCully, Curtis, Mihalenko, Cassidy, Newsome, Megan, O'Brien, John T., Pearson, Jeniveve, Pellegrino, Craig, Pierel, Justin D. R., Polin, Abigail, Rest, Armin, Rojas-Bravo, César, Sand, David J., Schwab, Michaela, Shahbandeh, Melissa, Shrestha, Manisha, Smith, Nathan, Strolger, Louis-Gregory, Szalai, Tamás, Taggart, Kirsty, Terreran, Giacomo, Terwel, Jacco H., Tinyanont, Samaporn, Valenti, Stefano, Vinkó, József, Wheeler, J. Craig, Yang, Yi, Zheng, Weikang, Ashall, Chris, Derkacy, James M., Galbany, Lluís, Hoeflich, Peter, Hsiao, Eric, De Jaeger, Thomas, Lu, Jing, Maund, Justyn, Medler, Kyle, Morrell, Nidia, Shappee, Benjamin J., Stritzinger, Maximilian, Suntzeff, Nicholas, Tucker, Michael, and Wang, Lifan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Nebular-phase observations of peculiar Type Ia supernovae (SNe Ia) provide important constraints on progenitor scenarios and explosion dynamics for both these rare SNe and the more common, cosmologically useful SNe Ia. We present observations from an extensive ground-based and space-based follow-up campaign to characterize SN 2022pul, a "super-Chandrasekhar" mass SN Ia (alternatively "03fg-like" SN), from before peak brightness to well into the nebular phase across optical to mid-infrared (MIR) wavelengths. The early rise of the light curve is atypical, exhibiting two distinct components, consistent with SN Ia ejecta interacting with dense carbon-oxygen rich circumstellar material (CSM). In the optical, SN 2022pul is most similar to SN 2012dn, having a low estimated peak luminosity ($M_{B}=-18.9$ mag) and high photospheric velocity relative to other 03fg-like SNe. In the nebular phase, SN 2022pul adds to the increasing diversity of the 03fg-like subclass. From 168 to 336 days after peak $B$-band brightness, SN 2022pul exhibits asymmetric and narrow emission from [O I] $\lambda\lambda 6300,\ 6364$ (${\rm FWHM} \approx 2{,}000$ km s$^{-1}$), strong, broad emission from [Ca II] $\lambda\lambda 7291,\ 7323$ (${\rm FWHM} \approx 7{,}300$ km s$^{-1}$), and a rapid Fe III to Fe II ionization change. Finally, we present the first-ever optical-to-mid-infrared (MIR) nebular spectrum of an 03fg-like SN Ia using data from JWST. In the MIR, strong lines of neon and argon, weak emission from stable nickel, and strong thermal dust emission (with $T \approx 500$ K), combined with prominent [O I] in the optical, suggest that SN 2022pul was produced by a white dwarf merger within carbon/oxygen-rich CSM., Comment: 23 pages, 11 figures, submitted to ApJ
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- 2023
222. Ground-based and JWST Observations of SN 2022pul: II. Evidence from Nebular Spectroscopy for a Violent Merger in a Peculiar Type-Ia Supernova
- Author
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Kwok, Lindsey A., Siebert, Matthew R., Johansson, Joel, Jha, Saurabh W., Blondin, Stephane, Dessart, Luc, Foley, Ryan J., Hillier, D. John, Larison, Conor, Pakmor, Ruediger, Temim, Tea, Andrews, Jennifer E., Auchettl, Katie, Badenes, Carles, Barna, Barnabas, Bostroem, K. Azalee, Newman, Max J. Brenner, Brink, Thomas G., Bustamante-Rosell, Maria Jose, Camacho-Neves, Yssavo, Clocchiatti, Alejandro, Coulter, David A., Davis, Kyle W., Deckers, Maxime, Dimitriadis, Georgios, Dong, Yize, Farah, Joseph, Filippenko, Alexei V., Flors, Andreas, Fox, Ori D., Garnavich, Peter, Gonzalez, Estefania Padilla, Graur, Or, Hambsch, Franz-Josef, Hosseinzadeh, Griffin, Howell, D. Andrew, Hughes, John P., Kerzendorf, Wolfgang E., Saux, Xavier K. Le, Maeda, Keiichi, Maguire, Kate, McCully, Curtis, Mihalenko, Cassidy, Newsome, Megan, O'Brien, John T., Pearson, Jeniveve, Pellegrino, Craig, Pierel, Justin D. R., Polin, Abigail, Rest, Armin, Rojas-Bravo, Cesar, Sand, David J., Schwab, Michaela, Shahbandeh, Melissa, Shrestha, Manisha, Smith, Nathan, Strolger, Louis-Gregory, Szalai, Tamas, Taggart, Kirsty, Terreran, Giacomo, Terwel, Jacco H., Tinyanont, Samaporn, Valenti, Stefano, Vinko, Jozsef, Wheeler, J. Craig, Yang, Yi, Zheng, WeiKang, Ashall, Chris, DerKacy, James M., Galbany, Lluis, Hoeflich, Peter, de Jaeger, Thomas, Lu, Jing, Maund, Justyn, Medler, Kyle, Morrell, Nidia, Shappee, Benjamin J., Stritzinger, Maximilian, Suntzeff, Nicholas, Tucker, Michael, and Wang, Lifan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present an analysis of ground-based and JWST observations of SN~2022pul, a peculiar "03fg-like" (or "super-Chandrasekhar") Type Ia supernova (SN Ia), in the nebular phase at 338d post explosion. Our combined spectrum continuously covers 0.4--14 $\mu$m and includes the first mid-infrared spectrum of an 03fg-like SN Ia. Compared to normal SN Ia 2021aefx, SN 2022pul exhibits a lower mean ionization state, asymmetric emission-line profiles, stronger emission from the intermediate-mass elements (IMEs) argon and calcium, weaker emission from iron-group elements (IGEs), and the first unambiguous detection of neon in a SN Ia. Strong, broad, centrally peaked [Ne II] line at 12.81 $\mu$m was previously predicted as a hallmark of "violent merger'' SN Ia models, where dynamical interaction between two sub-$M_{ch}$ white dwarfs (WDs) causes disruption of the lower mass WD and detonation of the other. The violent merger scenario was already a leading hypothesis for 03fg-like SNe Ia; in SN 2022pul it can explain the large-scale ejecta asymmetries seen between the IMEs and IGEs and the central location of narrow oxygen and broad neon. We modify extant models to add clumping of the ejecta to better reproduce the optical iron emission, and add mass in the innermost region ($< 2000$ km s$^{-1}$) to account for the observed narrow [O I]~$\lambda\lambda6300$, 6364 emission. A violent WD-WD merger explains many of the observations of SN 2022pul, and our results favor this model interpretation for the subclass of 03fg-like SN Ia., Comment: 20 pages, 10 figures, published in ApJ
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- 2023
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223. Decorrelating neurons using persistence
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Ballester, Rubén, Casacuberta, Carles, and Escalera, Sergio
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Computer Science - Machine Learning ,Mathematics - Algebraic Topology ,Statistics - Machine Learning ,55N31, 68T07 ,I.2.6 - Abstract
We propose a novel way to improve the generalisation capacity of deep learning models by reducing high correlations between neurons. For this, we present two regularisation terms computed from the weights of a minimum spanning tree of the clique whose vertices are the neurons of a given network (or a sample of those), where weights on edges are correlation dissimilarities. We provide an extensive set of experiments to validate the effectiveness of our terms, showing that they outperform popular ones. Also, we demonstrate that naive minimisation of all correlations between neurons obtains lower accuracies than our regularisation terms, suggesting that redundancies play a significant role in artificial neural networks, as evidenced by some studies in neuroscience for real networks. We include a proof of differentiability of our regularisers, thus developing the first effective topological persistence-based regularisation terms that consider the whole set of neurons and that can be applied to a feedforward architecture in any deep learning task such as classification, data generation, or regression., Comment: 15 pages, 4 figures
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- 2023
224. Generation of orchard and tree-child networks
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Cardona, Gabriel, Ribas, Gerard, and Pons, Joan Carles
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Quantitative Biology - Populations and Evolution - Abstract
Phylogenetic networks are an extension of phylogenetic trees that allow for the representation of reticulate evolution events. One of the classes of networks that has gained the attention of the scientific community over the last years is the class of orchard networks, that generalizes tree-child networks, one of the most studied classes of networks. In this paper we focus on the combinatorial and algorithmic problem of the generation of orchard networks, and also of tree-child networks. To this end, we use that these networks are defined as those that can be recovered by a reversing a certain reduction process. Then, we show how to choose a ``minimum'' reduction process among all that can be applied to a network, and hence we get a unique representation of the network that, in fact, can be given in terms of sequences of pairs of integers, whose length is related to the number of leaves and reticulations of the network. Therefore, the generation of networks is reduced to the generation of such sequences of pairs. Our main result is a recursive method for the efficient generation of all minimum sequences, and hence of all orchard (or tree-child) networks with a given number of leaves and reticulations. An implementation in C of the algorithms described in this paper, along with some computational experiments, can be downloaded from the public repository https://github.com/gerardet46/OrchardGenerator. Using this implementation, we have computed the number of orchard networks with at most 6 leaves and 8 reticulations., Comment: 13 pages, 4 figures
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- 2023
225. Density-polarity coupling in confined active polar films: asters, spirals, and biphasic orientational phases
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Dedenon, Mathieu, Dessalles, Claire A., Guillamat, Pau, Roux, Aurélien, Kruse, Karsten, and Blanch-Mercader, Carles
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Condensed Matter - Soft Condensed Matter ,Physics - Biological Physics - Abstract
Topological defects in active polar fluids can organise spontaneous flows and influence macroscopic density patterns. Both of them play, for example, an important role during animal development. Yet the influence of density on active flows is poorly understood. Motivated by experiments on cell monolayers confined to discs, we study the coupling between density and polar order for a compressible active polar fluid in presence of a +1 topological defect. As in the experiments, we find a density-controlled spiral-to-aster transition. In addition, biphasic orientational phases emerge as a generic outcome of such coupling. Our results highlight the importance of density gradients as a potential mechanism for controlling flow and orientational patterns in biological systems.
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- 2023
226. Competing effects in fourth-order aggregation-diffusion equations
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Carrillo, José Antonio, Esposito, Antonio, Falcó, Carles, and Fernández-Jiménez, Alejandro
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Mathematics - Analysis of PDEs ,35A01, 35A15, 35A21, 35D30, 35G20 - Abstract
We give sharp conditions for global in time existence of gradient flow solutions to a Cahn-Hilliard-type equation, with backwards second order degenerate diffusion, in any dimension and for general initial data. Our equation is the 2-Wasserstein gradient flow of a free energy with two competing effects: the Dirichlet energy and the power-law internal energy. Homogeneity of the functionals reveals critical regimes that we analyse. Sharp conditions for global in time solutions, constructed via the minimising movement scheme, also known as JKO scheme, are obtained. Furthermore, we study a system of two Cahn-Hilliard-type equations exhibiting an analogous gradient flow structure.
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- 2023
227. Particle realization of Bondi-Metzner-Sachs symmetry in 2+1 space-time
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Batlle, Carles, Campello, Víctor, and Gomis, Joaquim
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High Energy Physics - Theory - Abstract
We construct a Lorentz invariant massive particle model in (2+1) space-time with an enlarged set of symmetries which includes Bondi-Metzner-Sachs (BMS) translations (supertranslations), using the non-linear realization framework. The Hamiltonian formalism for the resulting Lagrangian is constructed, and the infinite phase-space constraints and the set of gauge transformations are analysed. We also compute the massless limit of the theory in phase-space. After eliminating the gauge degrees of freedom, the physical reduced space is left only with the degrees of freedom of a standard Poincar\'e particle but with a residual set of symmetries that we prove to be BMS. A similar result for the massless limit, including in this case superrotations, is pointed out., Comment: 30 pages, version accepted for publication in JHEP
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- 2023
228. PHOENI2X -- A European Cyber Resilience Framework With Artificial-Intelligence-Assisted Orchestration, Automation and Response Capabilities for Business Continuity and Recovery, Incident Response, and Information Exchange
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Fysarakis, Konstantinos, Lekidis, Alexios, Mavroeidis, Vasileios, Lampropoulos, Konstantinos, Lyberopoulos, George, Vidal, Ignasi Garcia-Milà, Casals, José Carles Terés i, Luna, Eva Rodriguez, Sancho, Alejandro Antonio Moreno, Mavrelos, Antonios, Tsantekidis, Marinos, Pape, Sebastian, Chatzopoulou, Argyro, Nanou, Christina, Drivas, George, Photiou, Vangelis, Spanoudakis, George, and Koufopavlou, Odysseas
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Computer Science - Cryptography and Security - Abstract
As digital technologies become more pervasive in society and the economy, cybersecurity incidents become more frequent and impactful. According to the NIS and NIS2 Directives, EU Member States and their Operators of Essential Services must establish a minimum baseline set of cybersecurity capabilities and engage in cross-border coordination and cooperation. However, this is only a small step towards European cyber resilience. In this landscape, preparedness, shared situational awareness, and coordinated incident response are essential for effective cyber crisis management and resilience. Motivated by the above, this paper presents PHOENI2X, an EU-funded project aiming to design, develop, and deliver a Cyber Resilience Framework providing Artificial-Intelligence-assisted orchestration, automation and response capabilities for business continuity and recovery, incident response, and information exchange, tailored to the needs of Operators of Essential Services and the EU Member State authorities entrusted with cybersecurity.
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- 2023
229. Summary characteristics for multivariate function-valued spatial point process attributes
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Eckardt, Matthias, Comas, Carles, and Mateu, Jorge
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Statistics - Methodology ,Statistics - Applications - Abstract
Prompted by modern technologies in data acquisition, the statistical analysis of spatially distributed function-valued quantities has attracted a lot of attention in recent years. In particular, combinations of functional variables and spatial point processes yield a highly challenging instance of such modern spatial data applications. Indeed, the analysis of spatial random point configurations, where the point attributes themselves are functions rather than scalar-valued quantities, is just in its infancy, and extensions to function-valued quantities still remain limited. In this view, we extend current existing first- and second-order summary characteristics for real-valued point attributes to the case where in addition to every spatial point location a set of distinct function-valued quantities are available. Providing a flexible treatment of more complex point process scenarios, we build a framework to consider points with multivariate function-valued marks, and develop sets of different cross-function (cross-type and also multi-function cross-type) versions of summary characteristics that allow for the analysis of highly demanding modern spatial point process scenarios. We consider estimators of the theoretical tools and analyse their behaviour through a simulation study and two real data applications., Comment: submitted for publication
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- 2023
230. Consumo de riesgo de alcohol y factores asociados en adolescentes de 15 a 16 años de la Cataluña Central: diferencias entre ámbito rural y urbano
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Núria Obradors-Rial, Carles Ariza, and Carles Muntaner
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Consumo de bebidas alcohólicas ,Binge drinking ,Adolescente ,Factores asociados ,Población rural ,Población urbana ,Public aspects of medicine ,RA1-1270 - Abstract
Objetivo: Conocer la prevalencia y los factores asociados al consumo de riesgo de alcohol entre los jóvenes de la Cataluña Central durante el curso 2011-2012 según el ámbito de residencia. Método: Estudio transversal, con una muestra de 1268 alumnos de 4° curso de ESO de la Cataluña Central. Resultados: El consumo de riesgo de alcohol es superior en los jóvenes que viven en un ámbito rural (59,6% versus 49,8%). Las borracheras de hermanos y amigos, tener expectativas positivas frente al consumo y haber comprado alcohol se asociaron al consumo de riesgo. En el ámbito rural se asociaron la situación familiar de convivencia diferente a la biparental y el bajo nivel académico, y en el ámbito urbano el alto nivel socioeconómico. Conclusiones: El consumo de riesgo de alcohol es muy superior entre los jóvenes del ámbito rural. Los principales factores asociados son los consumos de figuras del entorno familiar y escolar.
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- 2014
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231. Formación de la conciencia histórica y educación para el futuro
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Antoni Santisteban Fernández and Carles Anguera Cerarols
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historical thinking ,historical consciousness ,historical time ,education for the future ,prospectively ,Theory and practice of education ,LB5-3640 ,History (General) ,D1-2009 ,Latin America. Spanish America ,F1201-3799 - Abstract
In this article we pretend to prove the relations between two lines of research and inno-vation in the teaching of history and social sciences, both have important points of contact, although they belong to different scientific traditions. One is the development of historical consciousness; the other is the so called education for the future. The most obvious relation-ship between both traditions is their conception of the time and the importance that is given to the concept of future. Historical consciousness is temporal consciousness and helps us to relate the past with the present and with our ideas and ideals about the future. Education for the future aims to analyze the images that society has built for the future and at the same time, help to build capacities to think of alternative or desirable futures and act accordingly with responsibility and social commitment. In our opinion, both traditions are becoming more and more closer, as the historical–temporal consciousness points strongly to the future–present, and the education for the future needs to think about the past and the learning of temporality.
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- 2015
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232. La prevención de la obesidad infantil desde una perspectiva comunitaria
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Carles Ariza, Eduard Ortega-Rodríguez, Francesca Sánchez-Martínez, Sara Valmayor, Olga Juárez, and M. Isabel Pasarín
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Obesidad infantil ,Prevención universal ,Prevención selectiva ,Abordaje comunitario ,Medicine (General) ,R5-920 - Abstract
El porcentaje de fracasos y recaídas en el tratamiento de la obesidad es alto. Siempre que sea posible, la prevención de la obesidad para modificar hábitos alimentarios y estilos de vida ha de ser la conducta preferente. Este trabajo pretender ofrecer un marco de evidencia sobre los componentes más efectivos de las intervenciones para el abordaje de la obesidad infantil, tanto de su prevención como de su reducción, cuando esta ya está instaurada. A partir de la literatura científica, se presentan los aspectos que debe contemplar la prevención, tanto universal como selectiva, de la obesidad infantil. Habida cuenta también de la controversia sobre los instrumentos de registro y control del problema, se aportan algunos criterios clarificadores. Finalmente, se diferencia el abordaje de la prevención del sobrepeso y la obesidad con una perspectiva comunitaria, ofreciéndose 2 protocolos breves que esquematizan un procedimiento básico a seguir.
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- 2015
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233. Correction to: Ranking the Spanish regions according to their resilience capacity during 1965–2011
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Navinés, Ferran, Pérez-Montiel, José, Manera, Carles, and Franconetti, Javier
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- 2024
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234. Correction: The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium
- Author
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Bruin, Willem B, Abe, Yoshinari, Alonso, Pino, Anticevic, Alan, Backhausen, Lea L, Balachander, Srinivas, Bargallo, Nuria, Batistuzzo, Marcelo C, Benedetti, Francesco, Bertolin Triquell, Sara, Brem, Silvia, Calesella, Federico, Couto, Beatriz, Denys, Damiaan AJP, Echevarria, Marco AN, Eng, Goi Khia, Ferreira, Sónia, Feusner, Jamie D, Grazioplene, Rachael G, Gruner, Patricia, Guo, Joyce Y, Hagen, Kristen, Hansen, Bjarne, Hirano, Yoshiyuki, Hoexter, Marcelo Q, Jahanshad, Neda, Jaspers-Fayer, Fern, Kasprzak, Selina, Kim, Minah, Koch, Kathrin, Bin Kwak, Yoo, Kwon, Jun Soo, Lazaro, Luisa, Li, Chiang-Shan R, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Menchon, Jose M, Moreira, Pedro S, Morgado, Pedro, Nakagawa, Akiko, Nakao, Tomohiro, Narayanaswamy, Janardhanan C, Nurmi, Erika L, Zorrilla, Jose C Pariente, Piacentini, John, Picó-Pérez, Maria, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Reddy, Janardhan YC, Rodriguez-Manrique, Daniela, Sakai, Yuki, Shimizu, Eiji, Shivakumar, Venkataram, Simpson, Blair H, Soriano-Mas, Carles, Sousa, Nuno, Spalletta, Gianfranco, Stern, Emily R, Evelyn Stewart, S, Szeszko, Philip R, Tang, Jinsong, Thomopoulos, Sophia I, Thorsen, Anders L, Yoshida, Tokiko, Tomiyama, Hirofumi, Vai, Benedetta, Veer, Ilya M, Venkatasubramanian, Ganesan, Vetter, Nora C, Vriend, Chris, Walitza, Susanne, Waller, Lea, Wang, Zhen, Watanabe, Anri, Wolff, Nicole, Yun, Je-Yeon, Zhao, Qing, van Leeuwen, Wieke A, van Marle, Hein JF, van de Mortel, Laurens A, van der Straten, Anouk, van der Werf, Ysbrand D, Thompson, Paul M, Stein, Dan J, van den Heuvel, Odile A, and van Wingen, Guido A
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Biomedical and Clinical Sciences ,Biological Psychology ,Clinical and Health Psychology ,Clinical Sciences ,Psychology ,Machine Learning and Artificial Intelligence ,Mental Illness ,Serious Mental Illness ,Brain Disorders ,Anxiety Disorders ,Mental Health ,Good Health and Well Being ,ENIGMA-OCD Working Group ,Biological Sciences ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Psychiatry ,Clinical sciences ,Biological psychology ,Clinical and health psychology - Abstract
Correction to: Molecular Psychiatry, published online 2 May 2023 In this article Honami Arai, Irene Bollettini, Rosa Calvo Escalona, Ana Coelho, Federica Colombo, Leila Darwich, Martine Fontaine, Toshikazu Ikuta, Jonathan C. Ipser, Asier Juaneda-Seguí, Hitomi Kitagawa, Gerd Kvale, Mafalda Machado-Sousa, Astrid Morer, Takashi Nakamae, Jin Narumoto, Joseph O’Neill, Sho Okawa, Eva Real, Veit Roessner, Joao R. Sato, Cinto Segalàs, Roseli G. Shavitt, Dick J. Veltman, Kei Yamada were missing from the author list indexed under the ENIGMA-OCD Working Group. Additionally, there was an error regarding Tokiko Yoshida’s name, where the first name and last name were written in the wrong order. The original article has been corrected.
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- 2023
235. The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium.
- Author
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Bruin, Willem, Abe, Yoshinari, Alonso, Pino, Anticevic, Alan, Backhausen, Lea, Balachander, Srinivas, Bargallo, Nuria, Batistuzzo, Marcelo, Benedetti, Francesco, Bertolin Triquell, Sara, Brem, Silvia, Calesella, Federico, Couto, Beatriz, Denys, Damiaan, Echevarria, Marco, Eng, Goi, Ferreira, Sónia, Feusner, Jamie, Grazioplene, Rachael, Gruner, Patricia, Guo, Joyce, Hagen, Kristen, Hansen, Bjarne, Hirano, Yoshiyuki, Hoexter, Marcelo, Jahanshad, Neda, Jaspers-Fayer, Fern, Kasprzak, Selina, Kim, Minah, Koch, Kathrin, Bin Kwak, Yoo, Kwon, Jun, Lazaro, Luisa, Li, Chiang-Shan, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Menchon, Jose, Moreira, Pedro, Morgado, Pedro, Nakagawa, Akiko, Nakao, Tomohiro, Narayanaswamy, Janardhanan, Nurmi, Erika, Zorrilla, Jose, Picó-Pérez, Maria, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Reddy, Janardhan, Rodriguez-Manrique, Daniela, Sakai, Yuki, Shimizu, Eiji, Shivakumar, Venkataram, Simpson, Blair, Soriano-Mas, Carles, Sousa, Nuno, Spalletta, Gianfranco, Stern, Emily, Evelyn Stewart, S, Szeszko, Philip, Tang, Jinsong, Thomopoulos, Sophia, Thorsen, Anders, Yoshida, Tokiko, Tomiyama, Hirofumi, Vai, Benedetta, Veer, Ilya, Venkatasubramanian, Ganesan, Vetter, Nora, Vriend, Chris, Walitza, Susanne, Waller, Lea, Wang, Zhen, Watanabe, Anri, Wolff, Nicole, Yun, Je-Yeon, Zhao, Qing, van Leeuwen, Wieke, van Marle, Hein, van de Mortel, Laurens, van der Straten, Anouk, van der Werf, Ysbrand, Thompson, Paul, Stein, Dan, van den Heuvel, Odile, van Wingen, Guido, and Piacentini, John
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Humans ,Connectome ,Brain Mapping ,Magnetic Resonance Imaging ,Brain ,Obsessive-Compulsive Disorder ,Biomarkers ,Neural Pathways - Abstract
Current knowledge about functional connectivity in obsessive-compulsive disorder (OCD) is based on small-scale studies, limiting the generalizability of results. Moreover, the majority of studies have focused only on predefined regions or functional networks rather than connectivity throughout the entire brain. Here, we investigated differences in resting-state functional connectivity between OCD patients and healthy controls (HC) using mega-analysis of data from 1024 OCD patients and 1028 HC from 28 independent samples of the ENIGMA-OCD consortium. We assessed group differences in whole-brain functional connectivity at both the regional and network level, and investigated whether functional connectivity could serve as biomarker to identify patient status at the individual level using machine learning analysis. The mega-analyses revealed widespread abnormalities in functional connectivity in OCD, with global hypo-connectivity (Cohens d: -0.27 to -0.13) and few hyper-connections, mainly with the thalamus (Cohens d: 0.19 to 0.22). Most hypo-connections were located within the sensorimotor network and no fronto-striatal abnormalities were found. Overall, classification performances were poor, with area-under-the-receiver-operating-characteristic curve (AUC) scores ranging between 0.567 and 0.673, with better classification for medicated (AUC = 0.702) than unmedicated (AUC = 0.608) patients versus healthy controls. These findings provide partial support for existing pathophysiological models of OCD and highlight the important role of the sensorimotor network in OCD. However, resting-state connectivity does not so far provide an accurate biomarker for identifying patients at the individual level.
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- 2023
236. Endoscopic retrograde cholangiopancreatography for the management of choledocholithiasis in older patients
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Gardenyes, Julia, Roura, Pere, Vallverdu-Cartie, Helena, Hermoso-Bosch, Judit, Roca, Claudia, Espaulella, Mariona, Casals, Antoni, Marani, H. Ivo, Salo, Joan, Galdin, Martin, Gallach, Marta, and Leal, Carles
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- 2024
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237. Location of Coworking Spaces: Evidence from Spain
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Coll-Martínez, Eva, Méndez-Ortega, Carles, Mariotti, Ilaria, editor, Tomaz, Elisabete, editor, Micek, Grzegorz, editor, and Méndez-Ortega, Carles, editor
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- 2024
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238. Concluding Remarks on the Evolution of New Working Spaces
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Mariotti, Ilaria, Tomaz, Elisabete, Micek, Grzegorz, Méndez-Ortega, Carles, Mariotti, Ilaria, editor, Tomaz, Elisabete, editor, Micek, Grzegorz, editor, and Méndez-Ortega, Carles, editor
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- 2024
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239. Introduction to the Evolution of New Working Spaces
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Mariotti, Ilaria, Tomaz, Elisabete, Micek, Grzegorz, Méndez-Ortega, Carles, Mariotti, Ilaria, editor, Tomaz, Elisabete, editor, Micek, Grzegorz, editor, and Méndez-Ortega, Carles, editor
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- 2024
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240. Exploiting neural networks bit-level redundancy to mitigate the impact of faults at inference
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Catalán, Izan, Flich, José, and Hernández, Carles
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- 2025
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241. Hotel housekeepers in family hotel business: a perspective article
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Otegui Carles, Almudena
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- 2024
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242. The Timelessness of the Scar in the Borderline Personality Disorder BPD: A Systemic Intervention in a Case of Child Sexual Abuse
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Dominguez, Danilo, Pérez-Testor, Carles, Casarramona, Aina, and Aznar-Martínez, Berta
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- 2024
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243. Y-90 PET/MR imaging optimization with a Bayesian penalized likelihood reconstruction algorithm
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Calatayud-Jordán, José, Carrasco-Vela, Nuria, Chimeno-Hernández, José, Carles-Fariña, Montserrat, Olivas-Arroyo, Consuelo, Bello-Arqués, Pilar, Pérez-Enguix, Daniel, Martí-Bonmatí, Luis, and Torres-Espallardo, Irene
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- 2024
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244. Emerging and re-emerging infectious diseases in pregnant women in an amazonian region: a large retrospective study from French Guiana
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Hcini, Najeh, Lambert, Véronique, Carod, Jean-François, Mathieu, Meredith, Carles, Gabriel, Picone, Olivier, Sibiude, Jeanne, Pomar, Leo, and Nacher, Mathieu
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- 2024
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245. Differences in Subjective and Psychological Well-Being of Romanian Adolescents over a Four-Year Period and its Relationship with Free Time
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Tejada-Gallardo, Claudia, Bălţătescu, Sergiu, Alsinet, Carles, and Bacter, Claudia
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- 2024
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246. Characteristics of Young People Reporting a Low Sexual Desire in Switzerland
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Chok, Lorraine, Suris, Joan-Carles, and Barrense-Dias, Yara
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- 2024
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247. “Maybe They Don’t Necessarily Realize the Damage They Can Do…”: A Qualitative Study on Bystanders to Non-consensual Forwarding of Nudes Among Adolescents in Switzerland
- Author
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Barrense-Dias, Yara, Suris, Joan-Carles, and Chok, Lorraine
- Published
- 2024
- Full Text
- View/download PDF
248. Plant Names Encode Tašlḥit Knowledge of Morocco’s High Atlas Landscapes
- Author
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Soldal, Hanna, Múrcia, Carles, Ouhammou, Ahmed, Hawkins, Julie A., Martin, Gary J., Puri, Rajindra K., and Teixidor-Toneu, Irene
- Published
- 2024
- Full Text
- View/download PDF
249. White matter diffusion estimates in obsessive-compulsive disorder across 1653 individuals: machine learning findings from the ENIGMA OCD Working Group
- Author
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Kim, Bo-Gyeom, Kim, Gakyung, Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie, Anticevic, Alan, Arnold, Paul D., Balachander, Srinivas, Banaj, Nerisa, Bargalló, Nuria, Batistuzzo, Marcelo C., Benedetti, Francesco, Bertolín, Sara, Beucke, Jan Carl, Bollettini, Irene, Brem, Silvia, Brennan, Brian P., Buitelaar, Jan K., Calvo, Rosa, Castelo-Branco, Miguel, Cheng, Yuqi, Chhatkuli, Ritu Bhusal, Ciullo, Valentina, Coelho, Ana, Couto, Beatriz, Dallaspezia, Sara, Ely, Benjamin A., Ferreira, Sónia, Fontaine, Martine, Fouche, Jean-Paul, Grazioplene, Rachael, Gruner, Patricia, Hagen, Kristen, Hansen, Bjarne, Hanna, Gregory L., Hirano, Yoshiyuki, Höxter, Marcelo Q., Hough, Morgan, Hu, Hao, Huyser, Chaim, Ikuta, Toshikazu, Jahanshad, Neda, James, Anthony, Jaspers-Fayer, Fern, Kasprzak, Selina, Kathmann, Norbert, Kaufmann, Christian, Kim, Minah, Koch, Kathrin, Kvale, Gerd, Kwon, Jun Soo, Lazaro, Luisa, Lee, Junhee, Lochner, Christine, Lu, Jin, Manrique, Daniela Rodriguez, Martínez-Zalacaín, Ignacio, Masuda, Yoshitada, Matsumoto, Koji, Maziero, Maria Paula, Menchón, Jose M., Minuzzi, Luciano, Moreira, Pedro Silva, Morgado, Pedro, Narayanaswamy, Janardhanan C., Narumoto, Jin, Ortiz, Ana E., Ota, Junko, Pariente, Jose C., Perriello, Chris, Picó-Pérez, Maria, Pittenger, Christopher, Poletti, Sara, Real, Eva, Reddy, Y. C. Janardhan, van Rooij, Daan, Sakai, Yuki, Sato, João Ricardo, Segalas, Cinto, Shavitt, Roseli G., Shen, Zonglin, Shimizu, Eiji, Shivakumar, Venkataram, Soreni, Noam, Soriano-Mas, Carles, Sousa, Nuno, Sousa, Mafalda Machado, Spalletta, Gianfranco, Stern, Emily R., Stewart, S. Evelyn, Szeszko, Philip R., Thomas, Rajat, Thomopoulos, Sophia I., Vecchio, Daniela, Venkatasubramanian, Ganesan, Vriend, Chris, Walitza, Susanne, Wang, Zhen, Watanabe, Anri, Wolters, Lidewij, Xu, Jian, Yamada, Kei, Yun, Je-Yeon, Zarei, Mojtaba, Zhao, Qing, Zhu, Xi, Thompson, Paul M., Bruin, Willem B., van Wingen, Guido A., Piras, Federica, Piras, Fabrizio, Stein, Dan J., van den Heuvel, Odile A., Simpson, Helen Blair, Marsh, Rachel, and Cha, Jiook
- Published
- 2024
- Full Text
- View/download PDF
250. Frequency-Following Responses in Sensorineural Hearing Loss: A Systematic Review
- Author
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Jacxsens, Laura, Biot, Lana, Escera, Carles, Gilles, Annick, Cardon, Emilie, Van Rompaey, Vincent, De Hertogh, Willem, and Lammers, Marc J. W.
- Published
- 2024
- Full Text
- View/download PDF
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