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201. Interaction between [AT.sub.1] and [AT.sub.2] receptors during postinfarction left ventricular remodeling

Author

Voros, Szilard, Yang, Zequan, Bove, Christina M., Gilson, Wesley D., Epstein, Frederick H., French, Brent A., Berr, Stuart S., Bishop, Sanford P., Conaway, Mark R., Matsubara, Hiroaki, Carey, Robert M., and Kramer, Christopher M.

Subjects
Magnetic resonance imaging -- Research, Angiotensin -- Research, Angiotensin -- Health aspects, Heart attack -- Research, Biological sciences
Abstract

The relative contribution of the angiotensin II type 1 and 2 receptors ([AT.sub.1]-R and [AT.sub.2]-R) in postmyocardial infarction (MI) remodeling remains incompletely understood. We studied five groups of C57B1/6 mice after 1 h of left anterior descending artery occlusion-reperfusion: 1) wild type, untreated (n = 12); 2) wild type, treated with the [AT.sub.1]-R blocker losartan (10-20 mg x [kg.sup.-1] x [day.sup.-1] in drinking water) from day 1 to day 28 post-MI (n = 10); 3) cardiac overexpression of the [AT.sub.2]-R [[AT.sub.2]-transgenic (TG); n = 14]; 4) [AT.sub.2]-TG treated with losartan (n = 13); and 5) [AT.sub.2]-TG and null for the [AT.sub.1a]-R [[AT.sub.2]-TG/[AT.sub.1] knockout (KO); n = 10]. Cardiac magnetic resonance imaging (CMR) measured ejection fraction and left ventricular end-diastolic and end-systolic volume (EDVI and ESVI) and mass indexed to weight on days O, 1, 7, and 28 post-MI. Infarct size was measured on day 1 by late gadolinium-enhanced CMR. Regional myocyte hypertrophy and collagen content were measured on day 28 post-MI. Infarct size was similar among groups. Systolic blood pressure was lowest in [AT.sub.2]-TG/[AT.sub.1]KO. By day 28 post-MI, when corrected for baseline differences, EDVI and ESVI were higher and ejection fraction was lower in wild type than other groups. Ejection fraction was highest and EDVI and mass index were lowest in [AT.sub.2]-TG/[AT.sub.1]KO at day 28. The [AT.sub.2]-TG/[AT.sub.1]KO demonstrated less fibrosis in adjacent regions. Regional myocyte hypertrophy was similar in all groups. The [AT.sub.1]-R and [AT.sub.2]-R are intricately intertwined in post-MI remodeling. Pharmacological blockade of [AT.sub.1]-R is equivalent to [AT.sub.2]-R overexpression in attenuating post-MI remodeling. Genetic knockout of the [AT.sub.1a]-R is additive to [AT.sub.2]-R overexpression, due, at least in part, to blood pressure lowering. magnetic resonance imaging; angiotensin; myocardial infarction; receptors

Published
2006

208. List of Contributors

Author

Abdala, Ana P.L., primary, Adams, David H., additional, Alvarenga, Marlies, additional, Arnold, Amy C., additional, Axelrod, Felicia B., additional, Barbic, Franca, additional, Barnes, Peter J., additional, Bauer, Deborah, additional, Bell, Christopher, additional, Benarroch, Eduardo E., additional, Berry-Kravis, Elizabeth M., additional, Bernardi, Luciano, additional, Biaggioni, Italo, additional, Birder, Lori, additional, Brooks, Virginia L., additional, Heller Brown, Joan, additional, Burnstock, Geoffrey, additional, Camilleri, Michael, additional, Campbell, J.Preston, additional, Carey, Robert M., additional, Caron, Marc G., additional, Carter, Calvin, additional, Cassaglia, Priscila A., additional, Castillo, Javier G., additional, Chapleau, Mark W., additional, Charkoudian, Nisha, additional, David Charles, P., additional, Chelimsky, Gisela, additional, Chelimsky, Thomas, additional, Cheng, Pei-Wen, additional, Clément, Gilles, additional, Cortelli, Pietro, additional, Cowley, Allen W., additional, Crews, Leslie, additional, Davis, Stephen N., additional, Davis, Thomas L., additional, de Groat, William C., additional, DeMarco, Vincent G., additional, Diedrich, André, additional, DiPette, Donald J., additional, Diz, Debra I., additional, Drake, Marcus J., additional, Drew, Rachel C., additional, Dütsch, Matthias, additional, Eisenhofer, Graeme, additional, Elefteriou, Florent, additional, Elijovich, Fernando, additional, English, Brett A., additional, Esler, Murray, additional, Fang, John Y., additional, Fealey, Robert D., additional, Fernandez, Stanley, additional, Fink, Gregory D., additional, Floras, John S., additional, Freeman, Roy, additional, Fu, Qi, additional, Fu, Liang-Wu, additional, Furlan, Raffaello, additional, Gamboa, Alfredo, additional, Garland, Emily M., additional, Gibbons, Christopher H., additional, Gilbey, Michael P., additional, Gilden, Janice L., additional, Gilman, Sid, additional, Goldstein, David S., additional, Golombek, Diego A., additional, Graham, Robert M., additional, Grassi, Guido, additional, Grier, Mark D., additional, Groothuis, Jan T., additional, Grubb, Blair P., additional, Hahn, Maureen K., additional, Halcox, Julian P.J., additional, Hamill, Robert W., additional, Hande, Kenneth R., additional, Harati, Yadollah, additional, Harrison, David G., additional, Hart, Emma C., additional, Hastings, Jacqui, additional, Henderson, Luke A., additional, Hilz, Max J., additional, Hoeldtke, Robert, additional, Ho, Shung Tai, additional, Hunter, Peter, additional, Hyland, Keith, additional, Hyland, Lauren, additional, Izadyar, Shahram, additional, Izzo, Joseph L., additional, Jackson, Edwin K., additional, Jacob, Giris, additional, Jänig, Wilfrid, additional, Johnson, Megan S., additional, Jones, Carrie K., additional, Jones, James F.X., additional, Joos, Karen M., additional, Jordan, Jens, additional, Joyner, Michael J., additional, Kaler, Stephen G., additional, Kasparov, Sergey, additional, Kaufmann, Horacio, additional, Kaye, David, additional, Khurana, Ramesh K., additional, Kim, Chun-Hyung, additional, Kim, Kwang-Soo, additional, Kobayashi, Kazuto, additional, Kuntz, Nancy L., additional, Konecny, Tomas, additional, Kontak, Andrew, additional, Laffer, Cheryl L., additional, Lagrange, Andre H., additional, Laiken, Nora, additional, Lambert, Gavin, additional, Lenders, Jacques W.M., additional, Levine, Benjamin D., additional, Lipsitz, Lewis A., additional, Lombard, Julian H., additional, Longhurst, John C., additional, Low, David A., additional, Low, Phillip A., additional, Lu, Chih Cherng, additional, Luther, James M., additional, Macefield, Vaughan G., additional, McCully, Belinda H., additional, McLeod, James G., additional, Manger, William M., additional, Mano, Tadaaki, additional, Marvar, Paul J., additional, Masliah, Eliezer, additional, Mathias, Christopher J., additional, Melson, Mark R., additional, Milam, Douglas F., additional, Mohl, Marion C., additional, Molkov, Yaroslav I., additional, Morris, Margaret, additional, Morrison, Shaun F., additional, Nagatsu, Toshiharu, additional, Nichols, Charles D., additional, Norcliffe-Kaufmann, Lucy, additional, Novak, Vera, additional, Okamoto, Luis E., additional, Osborn, John W., additional, Parsons, Brian A., additional, Paton, Julian F.R., additional, Patwari, Pallavi P., additional, Phan, Cecile L., additional, Phibbs, Fenna T., additional, Prabhakar, Nanduri R., additional, Peltier, Amanda C., additional, Peterson, Sean M., additional, Pickering, Anthony E, additional, Pratt, J.Howard, additional, Rahmouni, Kamal, additional, Raj, Satish R., additional, Rand, Casey M., additional, Reichmann, Heinz, additional, Richards, Jeff, additional, Roberts, L.Jackson, additional, Robertson, David W., additional, Robertson, Rose Marie, additional, Robinson, Michael, additional, Rybak, Ilya A., additional, Sanders-Bush, Elaine, additional, Sandroni, Paola, additional, Sato, Kyoko, additional, Sato, Takayuki, additional, Schatz, Irwin J., additional, Schiffrin, Ernesto L., additional, Schondorf, Ronald, additional, Schwarz, Rosemary, additional, Seravalle, Gino, additional, Shapiro, Robert E., additional, Shibao, Cyndya, additional, Somers, Virend, additional, Stampfer, Michaela, additional, Stein, C.Michael, additional, Stemberger, Sylvia, additional, Stewart, Julian, additional, Sinoway, Lawrence I., additional, Sowers, James R., additional, Srikakarlapudi, Sirisha, additional, Sunagawa, Kenji, additional, Supowit, Scott C., additional, Taylor, Palmer, additional, Thompson, Jane, additional, Thijs, Roland D., additional, Touyz, Rhian M, additional, Tranel, Daniel, additional, Trikudanathan, Subbulaxmi, additional, Tseng, Ching-Jiunn, additional, Tung, Che-Se, additional, Ubhi, Kiren, additional, Urs, Nikhil, additional, Verbalis, Joseph G., additional, Vernino, Steven, additional, Victor, Ronald G., additional, Vizzard, Margaret A., additional, Vongpatanasin, Wanpen, additional, Wallin, B.Gunnar, additional, Wang, Tobias, additional, Wang, Qin, additional, Webster, Andrew A., additional, Weese-Mayer, Debra E., additional, Wenning, Gregor K., additional, Whaley-Connell, Adam, additional, Wieling, Wouter, additional, Williams, Gordon H., additional, Wood, Scott, additional, Ziegler, Michael G., additional, and Zoccal, Daniel B., additional

Published
2012
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218. List of Contributors

Author

Adell, Albert, primary, Andrade, Rodrigo, additional, Artigas, Francesc, additional, Azmitia, Efrain C., additional, Bailer, Ursula F., additional, Beck, Sheryl D., additional, Blue, Mary E., additional, Bockaert, Joël, additional, Bortolato, Marco, additional, Bortolozzi, Analía, additional, Canli, Turhan, additional, Carey, Robert J., additional, Carr, Gregory V., additional, Cassel, Jean-Christophe, additional, Celada, Pau, additional, Chen, Kevin, additional, Claeysen, Sylvie, additional, Clifton, Peter G., additional, Craig, Ian W., additional, Crockett, Molly J., additional, Cryan, John F., additional, D'Souza, Ursula M., additional, Ben, Cristina Marta Del, additional, Denys, Damiaan, additional, Descarries, Laurent, additional, Dîaz-Mataix, Llorenç, additional, Dohle, Carolin I., additional, Duman, Elif Aysimi, additional, Dumuis, Aline, additional, Duvvuri, Vikas, additional, Feenstra, Matthijs G.P., additional, Fornal, Casimir A., additional, Friedel, Eva, additional, Geyer, Mark A., additional, Graeff, Frederico Guilherme, additional, Guimarães, Francisco Silveira, additional, Guptarak, Jutatip, additional, Hale, Matthew W., additional, Hasegawa, Hiroyuki, additional, Heinz, Andreas, additional, Hensler, Julie G., additional, Hohmann, Christine F., additional, Hornung, Jean-Pierre, additional, Hoyer, Daniel, additional, Huston, Joseph P., additional, Jacobs, Barry L., additional, Kaye, Walter H., additional, Klompmakers, Andre, additional, Lee, Michelle D., additional, Linthorst, Astrid C.E., additional, Lowry, Christopher A., additional, Lucki, Irwin, additional, Marek, Gerard J., additional, Marin, Philippe, additional, Marsden, Charles A., additional, McBride, William J., additional, Mengod, Guadalupe, additional, Miczek, Klaus A., additional, Müller, Christian P., additional, Nakamura, Kazuhiro, additional, Nichols, David E., additional, O'Leary, Olivia F., additional, Oades, Robert D., additional, Parent, Martin, additional, Pum, Martin E., additional, Quadros, Isabel M., additional, Quednow, Boris B., additional, Reul, Johannes M.H.M., additional, Reynolds, Gavin P., additional, Riad, Mustapha, additional, Richerson, George B., additional, Robbins, Trevor W., additional, Santana, Noemí, additional, Schumann, Gunter, additional, Sharp, Trevor, additional, Shih, Jean C., additional, Sommer, Claudia, additional, Takahashi, Aki, additional, Uphouse, Lynda, additional, van der Plasse, Geoffrey, additional, van Dijk, Addy, additional, Vertes, Robert P., additional, Vilaró, M. Teresa, additional, Whitaker-Azmitia, Patricia M., additional, Yevtushenko, Olga O., additional, and Zangrossi, Hélio, additional

Published
2010
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219. Contributors

Author

Aiello, Lloyd Paul, primary, Alexander, Erik K., additional, Allan, Carolyn A., additional, Allolio, Bruno, additional, Angelos, Peter, additional, Appu, Sree, additional, Auchus, Richard J., additional, Avruch, Joseph, additional, Axelrod, Lloyd, additional, Bahn, Rebecca S., additional, Baker, H.W.G., additional, Barnes, Randall B., additional, Bastepe, Murat, additional, Baxter, John D., additional, Beck-Peccoz, Paolo, additional, Bell, Graeme I., additional, Bilezikian, John P., additional, Bloom, Stephen R., additional, Blum, Manfred, additional, Bonnema, Steen J., additional, Botero, Diego, additional, Bouillon, Roger, additional, Boulton, Andrew J.M., additional, Braunstein, Glenn D., additional, Bringhurst, F. Richard, additional, Broekmans, Frank J., additional, Bronstein, Marcello D., additional, Brown, Edward M., additional, Bui, Chuong, additional, Burch, Col. Henry B., additional, Burger, Henry G., additional, Burney, Richard O., additional, Buse, John B., additional, Butler, Peter C., additional, Cappabianca, Paolo, additional, Caramori, Maria Luiza Avancini, additional, Carey, Robert M., additional, Carlton, Esther, additional, Carmody, David, additional, Caro, Jose F., additional, Cavagnini, Francesco, additional, Cavallerano, Jerry, additional, Cavallo, Luigi M., additional, Chan, Shu Jin, additional, Chang, R. Jeffrey, additional, Chapurlat, Roland D., additional, Chatterjee, V. Krishna, additional, Chiovato, Luca, additional, Cho, Kyung J., additional, Christophe, Daniel, additional, Chung, Teng-Teng, additional, Cidlowski, John A., additional, Clark, Adrian J.L., additional, Clark, Peter E., additional, Clemmons, David R., additional, Considine, Robert V., additional, Copinschi, Georges, additional, Copps, Kyle D., additional, Courtney, C. Hamish, additional, Cuttler, Leona, additional, Daley, Melita L., additional, Dattani, Mehul, additional, Davis, Stephen N., additional, de Divitiis, Oreste, additional, De Felice, Mario, additional, DeFronzo, Ralph A., additional, J. De Groot, Leslie, additional, de Kretser, David, additional, Delli, Ahmed J., additional, Delmas, Pierre D., additional, Demay, Marie B., additional, Devroey, Paul, additional, Di Lauro, Roberto, additional, Dinneen, Sean F., additional, Dumont, Jacques E., additional, Dungan, Kathleen M., additional, Drucker, Daniel J., additional, Econs, Michael J., additional, Ehrmann, David A., additional, Eisenhofer, Graeme, additional, Erickson, Gregory F., additional, Eriksson, Barbro, additional, Espiner, Eric, additional, Esposito, Felice, additional, Esser, Victoria, additional, Eugster, Erica A., additional, Farooqi, Sadaf, additional, Fassnacht, Martin, additional, Fauser, Bart C.J.M., additional, Fenzi, Gianfranco, additional, Ferrannini, Ele, additional, Findlay, David M., additional, Finlayson, Courtney, additional, Fisher, Delbert A., additional, Forest, Maguelone G., additional, Foster, Daniel W., additional, Freeman, Mason Wright, additional, Frydenberg, Mark, additional, Fuller, Peter, additional, Gagel, Robert F., additional, Gaglia, Jason L., additional, Galizia, Gianluigi, additional, Gao, Chuanyun, additional, Gardella, Thomas J., additional, Gaylinn, Bruce D., additional, Genant, Harry K., additional, German, Michael S., additional, Ghatei, Mohammad A., additional, Giudice, Linda C., additional, Glasier, Anna, additional, Glorieux, Francis H., additional, González-Maeso, Javier, additional, Gooren, Louis J., additional, Gordon, David F., additional, Gregerson, Karen A., additional, Gross, Milton D., additional, Grossman, Ashley, additional, Guimarães, Valéria C., additional, Gurnell, Mark, additional, Haddad, Nadine, additional, Haisenleder, Daniel J., additional, Handelsman, David J., additional, Hanks, John B., additional, Hannon, Mark John, additional, Hayward, Simon W., additional, Hebrok, Matthias, additional, Hegedüs, Laszlo, additional, Hennemann, Georg, additional, Herndon, Maria K., additional, Hindmarsh, Peter, additional, Ho, Ken K.Y., additional, Horseman, Nelson D., additional, Horwitz, Mara J., additional, Hu, Mimi, additional, Hughes, Ieuan A., additional, Hupfeld, Christopher J., additional, Hussain, Hero K., additional, Illingworth, Peter, additional, Jameson, J. Larry, additional, Josso, Nathalie, additional, Jüppner, Harald, additional, Kalish, Jeffrey, additional, Kaplan, Edwin L., additional, Kerr, Jeffrey B., additional, Klein, Ronald, additional, Knobel, Meyer, additional, Kolibianakis, Efstratios, additional, Kopchick, John J., additional, Kopp, Peter, additional, Korbonits, Márta, additional, Korobkin, Melvyn, additional, Krane, Stephen M., additional, Krohn, Knut, additional, Kronenberg, Henry M., additional, Kyriakis, John M., additional, Lau, Sue Lynn, additional, Lazarus, John H., additional, Learoyd, Diana L., additional, Lebovitz, Harold E., additional, Lee, Paul, additional, Lernmark, Åke, additional, Lewis-Tuffin, Laura J., additional, Lu, Zhi-Liang, additional, Macchia, Paolo Emidio, additional, Maclaren, Noel K., additional, Maenhaut, Carine, additional, Maes, Christa, additional, Main, Katharina M., additional, Malchoff, Carl D., additional, Malchoff, Diana Mark, additional, Malik, Rayaz A., additional, Mandel, Susan J., additional, Mantzoros, Christos, additional, Maratos-Flier, Eleftheria, additional, Marchisotta, Stefania, additional, Marinò, Michele, additional, Marshall, John C., additional, Martin, Thomas F.J., additional, Martin, T. John, additional, Martos-Moreno, Gabriel Á., additional, Mathias, Christopher J., additional, Mauer, Michael, additional, McGee, Elizabeth A., additional, McKenna, Neil J., additional, McLachlan, Robert I., additional, Medeiros-Neto, Geraldo, additional, Meier, Juris J., additional, Melmed, Shlomo, additional, Metzger, Boyd E., additional, Millar, Robert, additional, Miller, Walter L., additional, Misra, Madhusmita, additional, Molitch, Mark E., additional, Moore, David D., additional, Morris, Damian G., additional, Munck, Allan U., additional, Nakamoto, Jon, additional, Náray-Fejes-Tóth, Anikó, additional, Nass, Ralf, additional, Nathan, David M., additional, New, Maria I., additional, Nguyen, Carolyn, additional, Nieman, Lynnette K., additional, Nilson, John H., additional, Norton, Jeffrey A., additional, Oakley, Robert H., additional, Öberg, Kjell, additional, Olefsky, Jerrold M., additional, O’Rahilly, Stephen, additional, Ozcan, Umut, additional, Pacak, Karel, additional, Pacini, Furio, additional, Padia, Shetal H., additional, Paschke, Ralf, additional, Pawson, Adam, additional, Peck, Alison C., additional, Giraldi, Francesca Pecori, additional, Persani, Luca, additional, Phelps, Richard L., additional, Philipson, Louis H., additional, Phillips, Kevin, additional, Pinchera, Aldo, additional, Pomposelli, Frank B., additional, Potts, John T., additional, Quigley, Charmian A., additional, Quinkler, Marcus, additional, Quirk, Christine Campion, additional, Rademaker, Miriam T., additional, Meyts, Ewa Rajpert-De, additional, Ravussin, Eric, additional, Ray, David W., additional, Reame, Nancy King, additional, Refetoff, Samuel, additional, Retnakaran, Ravi, additional, Rey, Rodolfo A., additional, Rhodes, Christopher J., additional, Ridgway, E. Chester, additional, Risbridger, Gail P., additional, Rizza, Robert A., additional, Robinson, Bruce, additional, Roger, Pierre P., additional, Rosenfeld, Michael G., additional, Rosenfield, Robert L., additional, Rosing, James H., additional, Rossing, Peter, additional, Rubin, Robert T., additional, Ruderman, Neil, additional, Russo, Irma H., additional, Russo, Jose, additional, Salameh, Wael Antoine, additional, Salusky, Isidoro B., additional, Samuels, Mary H., additional, Santen, Richard J., additional, Santoro, Nanette, additional, Sarapura, Virginia D., additional, Sealfon, Stuart C., additional, Sexton, Patrick M., additional, Shulman, Gerald I., additional, Silva, Paolo S., additional, Silverberg, Shonni J., additional, Singer, Frederick R., additional, Skakkebaek, Niels E., additional, Skowronska-Krawczyk, Dorota, additional, Smith, Carolyn L., additional, Smith, Philip W., additional, Smith, Roger, additional, Smith, Steven R., additional, Snyder, Peter J., additional, Stanhope, Richard, additional, St-Arnaud, René, additional, Steiner, Donald F., additional, Stevens, Adam, additional, Stewart, Andrew F., additional, Stewart, Paul M., additional, St. Germain, Donald L., additional, Stockigt, Jim, additional, Strauss, Jerome F., additional, Swiersz, Lillian Marie, additional, Tacon, Lyndal J., additional, Taheri, Shahrad, additional, Thakker, Rajesh V., additional, Thompson, Chris, additional, Thorner, Michael O., additional, Timmers, Henri J.L.M., additional, Toppari, Jorma, additional, Traggiai, Cristina, additional, Traub, Michael L., additional, Tseng, Yolanda, additional, Turek, Fred W., additional, Van Cauter, Eve, additional, Van den Berghe, Greet, additional, Van Steirteghem, André C., additional, Vassart, Gilbert, additional, Vilain, Eric, additional, Visser, Theo J., additional, Wajnrajch, Michael P., additional, Wand, Gary, additional, Webb, Paul, additional, Weetman, Anthony P., additional, Weigel, Nancy L., additional, Weir, Gordon C., additional, Weiss, Roy E., additional, Wesseling-Perry, Katherine, additional, White, Anne, additional, White, Kenneth E., additional, White, Morris F., additional, Whyte, Michael P., additional, Wiersinga, Wilmar M., additional, Wolfsdorf, Joseph I., additional, and Zinman, Bernard, additional

Published
2010
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227. List of Contributors

Author

Adler, Gail K., primary, Ayus, Juan Carlos, additional, Bakris, George, additional, Berl, Tomas, additional, Bollag, Wendy B., additional, Brown, Alex J., additional, Burnett, John C., additional, Cai, Zheqing, additional, Carey, Robert M., additional, Catanzaro, Daniel F., additional, Coghlan, John, additional, Dusso, Adriana S., additional, Ecelbarger, Carolyn A., additional, Ferrario, Carlos M., additional, Friedman, Peter A., additional, Galigniana, Mario, additional, Garg, Rajesh, additional, Gomez-Sanchez, Celso E., additional, Gomez-Sanchez, Elise P., additional, Isales, Carlos M., additional, Jüppner, Harald, additional, Ananth Karumanchi, S., additional, Keithi-Reddy, Sairam, additional, Ko, Benjamin, additional, Kraut, Jeffrey A., additional, Lam, Chun, additional, Lee, Candace Y.W., additional, Lim, Victoria S., additional, Lin, Herbert Y., additional, Macdougall, Iain C., additional, Mahan, John D., additional, Menard, Joel, additional, Mole, David R., additional, Moritz, Michael L., additional, Nagami, Glenn T., additional, Padia, Shetal H., additional, Palmer, Biff F., additional, Patel, Tejas, additional, Pendse, Shona, additional, Portale, Anthony A., additional, Rainey, William E., additional, Ratcliffe, Peter J., additional, Reudelhuber, Timothy L., additional, Sands, Jeff M., additional, Schlanger, Lynn E., additional, Schrier, Robert W., additional, Semenza, Gregg L., additional, Singh, Ajay K., additional, Sica, Domenic A., additional, Simonson, Donald C., additional, Suneja, Manish, additional, Tait, James F., additional, Tiwari, Swasti, additional, and Trask, Aaron J., additional

Published
2009
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233. Contributors

Author

Abramovitz, Blaise W., Agarwal, Rajiv, Ahmad, Sarah, Alexander, Matthew R., AlQassas, Ibrahim A., Arroyo, Juan P., Asuzu, Christopher, Ayesh, Ali, Bakris, George, Bali, Atul, Beckman, Joshua A., Bock, Fabian, Bugeja, Ann, Burgner, Anna, Carey, Robert M., Cohen, Jordana B., Concepcion, Beatrice P., Dillingham, Christine, Drager, Luciano F., Dresser, George K., Eknoyan, Garabed, Ellison, David, Erdbrugger, Uta, Farrell, Maureen C., Flood, Ryan P., Flynn, Joseph T., Georgianos, Panagiotis I., Gilligan, Sarah, McAuliffe, Christin Giordano, Hiremath, Swapnil, Holder, Tara A., Hu, Jiun-Ruey, Husain, Irma, Imran, Nashat, Judd, Eric, Kharadjian, Talar B., Kim, Esther S., Kovach, Cassandra, Kumar, Arun, Lerma, Edgar V., Lewis, Julia B., Libianto, Renata, Lloyd, Matthew, Luther, James M., Malhotra, Rakesh, Mehta, Hina N., Montford, John R., Mosley, Jonathan D., Munir, Bilal, Padwal, Raj, Patel, Trisha, Peixoto, Aldo J., Pradhan, Nishigandha, Pratt, J. Howard, Puar, Akshan, Rabkin, Simon W., Rahman, Mahboob, Raj, Satish R., Ramkumar, Nirupama, Rianto, Fitra, Ringrose, Jennifer, Ruzicka, Marcel, Schiavon, Carlos A., Shamy, Michel, Shawar, Saed, Shibao, Cyndya A., Sparks, Matthew A., Sternlicht, Hillel, Sussman, Craig, Terker, Andrew, Tezuka, Yuta, Tran, Karen C., Turcu, Adina F., Vaidya, Anand, and Yang, Jun

Published
2023
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241. Robert J. Carey: Department of Defense Principal Deputy Chief Information Officer

Author

Carey, Robert J.

Subjects
United States. Department of Defense, Chief information officers, Government, Political science
Abstract

Mr. Carey entered the Senior Executive Service in June 2003 as the DON Deputy Chief Information Officer (Policy and Integration) and was responsible for leading the DON CIO staff in [...]

Published
2012

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