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The aim of this community service activity is to enhance the scientific literacy skills of lower-grade students in Kesetnana village through educational game-based lessons. The activity is conducted in several stages, including planning, preparation, implementation, evaluation, and reporting. The outcome of this initiative is the development of educational game media and its utilization in the teaching process, resulting in a significant increase in scientific literacy skills of over 65%. Additionally, students' interest in learning has risen by 68.8% according to indicators of learning motivation, demonstrating their positive response to the educational game-based approach. Therefore, efforts to promote scientific literacy among lower-grade elementary school students in Kesetnana village can be effectively carried out through regular lesson activities over a three-week period, leading to improved scientific literacy skills and increased learning motivation.

In the European Union (EU) a new framework was established in December of 2022, the “Safe and Sustainable-by-Design” framework. This framework was created to enhance the risk assessment of new chemicals in order to avoid regrettable substitutions, and integrate sustainable development goals in the invention of new thechnologies. To implement SSbD, interpretations of the framework were developed to facilitate its implementation. An example is the European Joint Research Centre (JRC) that developed an interpretation of SSbD. Perovskite are a broad class of crystalline materials of ABX3 chemical composition, where A and B are metal cations and X is a anion. The application of perovskites nowadays is very extensive from ferroelectrics, superconductors, solar cells and automotive catalysts. Oxide-perovskites are more specifically formed in the ABO3 formation. This thesis aims at presenting a case study of automotive catalysts oxide-perovskites LanthanumCobalt-Nickel (LaCoNi) and providing an overview of the JRC interpretation of the SSbD framework using the LaCoNi case study with a focus on environmental safety. For this, ecotoxic studies on the metal ions composing the perovskites and the material itself were conducted. The results were related to the JRC framework and a discussion on the relevance of the results was done to provide some insight of the application of the JRC SSbD framework. The ecotoxic study was conducted on R. subcapitata freshwater algae as well as D. magna freshwater daphids. The results showed an EC50 of 30.2 mg/L for LaCoNi on the algae and no effects on the daphnids in concentrations up-to 100 mg/L. These results showed that LaCoNi could be potentially harmful to the environment because of the leachability of nickel and cobalt, and that many more studies on the effect on human would be needed as required by the JRC framework. The applicability of the JR

Salah satu tanaman yang digunakan secara tradisional adalah tanaman Faloak. Tanaman faloak banyak digunakan dalam pengobatan tradisional di Nusa Tenggara Timur. Daun faloak diduga memiliki efek hepatoprotektif berdasarkan kemampuannya sebagai antioksidan, yaitu salah satu mekanisme hepatoprotektif untuk melawan radikal bebas yang berkontribusi terhadap kerusakan jaringan hati. Penelitian ini bertujuan Untuk Mengetahui dosis fraksi daun faloak (Sterculia quadrifida R. Br.) yang efektif terhadap hepatoprotektor dengan parameter makropatologi pada organ hati pada tikus. Penelitian ini merupakan penelitian eksperimen yang menggunakan hewan uji tikus putih jantan sebanyak 30 ekor yang dibagi dalam 6 kelompok perlakuan. Pada penelitian ini dilakukan penimbangan berat badan tikus pada hari ke 0 sampai hari ke-15 untuk mengetahui perubahan berat badan tikus yang terjadi. Hasil penimbangan berat badan tikus menunjukan bahwa tidak ada perbedaan secara signifikan. kerusakan pada organ hati ini tidak ditemukan pada kelompok yang diberikan kurkumin, fraksi air daun faloak dosis 50mg/kgBB, 100mg/kg/BB, 200mg/KgBB tetapi ditemukan dalam kelompok kontrol CMC 1%. Fraksi air daun faloak dosis 50mg/kgBB, 100mg/kgBB, 200mg/kgBB secara makroskopik mampu melindungi kerusakan hati akibat pemberian paracetamol dosis toksik.

Abrasion of tire tread, caused by friction between vehicle tires and road surfaces, causes release of tire wear particles (TWPs) into various environmental compartments. TWPs contribute to chemical-, microplastic-, and particulate matter pollution. Their fate remains largely unknown, especially regarding the extent and form in which they persist in the environment. This study investigated 1) the biodegradability of tread particles (TPs) in the form of ground tire tread, 2) how accelerated UV-weathering affect their biodegradability, and 3) which TP constituents are likely contributors to TP biodegradability based on their individual biodegradability. A series of closed bottle tests, with aerobic aqueous medium inoculated with activated sludge, were carried out for pristine TPs, UV-weathered TPs, and selected TP constituents; natural rubber (NR), isoprene rubber (IR), butadiene rubber (BR), and treated distillate aromatic extracts (TDAE). Biodegradation was monitored by manometric respirometry quantifying biological oxygen consumption over 28 days. Pristine TP biodegradability was found to be 4.5%. UV-weathered TPs showed higher biodegradability of 6.7% and 8.0% with similar and increased inoculum concentration, respectively. The observed TP biodegradation was mainly attributed to biodegradation of NR and TDAE, with individual biodegradability of 35.4% and 8.0%, respectively. IR and BR showed negligible biodegradability. These findings indicate biodegradability of individual constituents is decreased by a factor of 2 to 5 when compounded into TPs. Through scanning electron microscope (SEM) analysis, biodegradation was found to cause surface erosion. Processes of TP biodegradation are expected to change throughout their lifetime as new constituents are incorporated from the road and others degrade and/or leach out. Tire emissions likely persist as particles with an increased fraction of synthetic rubbers and carbon black.