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In the context of the health risks of the COVID-19 pandemic, tourists' choices have shifted to reflect a subconscious psychological mechanism - the behavioral immune system - that facilitates human organisms to better identify plausible threats to ones' health through environment cues. This research draws upon this theoretical lens to assess tourists' pre-trip hotel evaluation in two 2 × 2 between-subject experiments. Experiment 1 (robot vs. human) tested the service provider's effect on hotel selection evaluation through the mediation of sense of control and the moderation of pandemic risk. Experiment 2 examined this chain of relationship through the moderation of hotel type. This research contributes to the literature by underscoring the pathogen-avoidance mechanism in tourist evaluation and the peril of robotization.

This study develops a multilevel framework that connects customer-to-customer (C2C) interaction quality to brand attachment through customer experience. Two food traits—uniqueness and taste—and service quality are posited to play different roles in this link. This research contributes to the literature on the effects of food traits and service on the experience creation process at upscale restaurants. By including both objective measures from user-generated ratings and subjective measures from customer evaluations of restaurant dining, this research sheds new light on the cross-level direct and moderating effects on the experience creation process, and thus answers the question of when and how this process is contingent on food traits and service of different dining outings. It further contributes to the brand attachment literature by revealing the cross-level moderated mediating effect of customer experience on customer emotional connection to a restaurant brand.

The COVID-19 pandemic aftermath has aggravated its traumatic effect to engender a mental health crisis. With increasingly worsened psychological wellbeing, it is the responsibility of tourism scholars and operators alike to explore how contemporary tourism offerings can enable individuals to rebuild hope and optimism through relishing tourism's restorative appeals amid rigid border lockdowns. However, it remains unclear whether tourists are able to restore themselves from staycation programs, since tourists have a tendency to favor a novel space, as opposed to a usual travel environment. To address this question, we relied upon a government-funded staycation campaign using a survey to assess a transformative process leading from travel motivation and restoration to fortifying psychological capital and wellbeing. Drawing on theories pertaining to attention restoration, psychological capital, and involvement, our findings unravel a travel transformative mechanism of staycation programs that build a linkage between travel motivation and favorable psychological outcomes amid adverse circumstances.

Post-transplantation cardiac xenograft growth in an orthotopic pig to baboon model is a life-limiting phenomenon that is poorly understood. Possible causes of growth include both intrinsic and extrinsic etiologies. Extrinsic causes are thought to be attributed to maladaptive hypertrophy as a result of increased mean arterial pressure experienced by the cardiac xenograft after transplantation. Intrinsic causes are thought to be a result of discordant growth between pig xenografts and recipients. This results in intrinsic xenograft growth that parallels the donor and continues in a recipient in which growth is relatively minimal, controlled in part by the growth hormone receptor, IGF-1 axis. Recently, Zaman, et al. published a study titled, “Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress,” in Immunity, Volume 54; Issue 9, pp. 2057–2071. They demonstrated that insulin growth factor-secreting resident macrophages that sense hypertensive stress are a mechanistic link to hypertension and maladaptive hypertrophy in the setting of hypertension. While notable in its own right, we comment on how this work may shed light on a new underlying mechanism for the use of growth hormone receptor knockout (GHRKO) pig donors and its role in addressing post-transplantation xenograft growth. We hypothesize that GHRKO pig donors contain syngeneic resident cardiac macrophages that abrogate IGF-1 mediated maladaptive hypertrophy from hypertension. Futures studies in post-transplantation cardiac xenotransplantation growth should examine this mechanism as a potential contributor.

Training is a vital means to continuously improve service quality. Although much literature has concentrated on the relationship between on-the-job training and job outcomes, these studies are usually static and cross-sectional in research design, which fails to capture the dynamic changes of training outcomes. This study attempted to address this issue by adopting a learning and development perspective. Drawing on psychological capital theory and self-determination theory, we examined how training progress facilitates trainees’ personal growth and psychological development. Specifically, we utilized the latent growth modeling approach to examine hotel employees’ trajectory of change regarding service knowledge, self-efficacy and job satisfaction over the pre-training, mid-training, and post-training stages. By surveying full-time trainees working in three luxury hotels, we found that the mean level of employees’ service knowledge would increase over time, while this improvisation would also result in gradual enhancement of self-efficacy and job satisfaction.

Dining in Internet-celebrity (or micro-celebrity) restaurants is an increasingly popular indulgence. Rooted in the micro-celebrity economy research, the present study draws on self-signaling and self-determination theories to propose an integrated research framework that examines how extrinsic and intrinsic factors impact customers’ intention to revisit micro-celebrity restaurants. External social needs (i.e., restaurant competence, signaling identity, and foodstagramming benefits) and internal personality traits (i.e., neophilic and neophobic tendencies) are synthesized to better understand their impacts on conative propensities. The findings indicate that foodstagramming benefits mediates the relationship between restaurant competence and intention to revisit, whereas neophilic renders a boundary condition suppressing this relationship. However, neophilic and neophobic tendencies positively moderate the effect of identity-signaling.

The analysis of tourism supply chains has traditionally focused on the two-party relationships between vertical suppliers. However, since a full supply chain is composed of horizontal, vertical and diagonal suppliers, there is a gap in literature regarding the dynamics of how these triadic relationships operate within a tourism supply chain. Using a multiple case study design involving four tour operators in Macau, this paper explores the interplay of relationships among horizontal, vertical and diagonal suppliers. We capture the evolutionary dynamics of how coopetitive relationships are formed between horizontal suppliers, the subsequent impact on both vertical and diagonal suppliers, and the resulting overall changes in the structure of the tourism supply chain. This paper contributes to tourism supply chain literature through a coopetitive lens by analyzing the triadic relational links among horizontal, vertical and diagonal suppliers.

Purpose This paper, from a marketing and management perspective, aims to review the relevant literature germane to casino studies. The review discusses the major findings from previous studies, provides a critique and identifies research gaps for future studies. In particular, the research foci presented in this paper rest on the service profit chain (SPC) model. The review involves studies relating to the constructs of the chain model and comprises sections that are categorized based on the internal link between management and employees, interaction between casino service employees and customers and profitability link. Design/methodology/approach The approach used in the current study involves a systematic review of the relevant academic literature with a focus on SPC studies in the casino industry, along with critical evaluation and analysis to identify research gaps. Google Scholar, EBSCOHost, Science Direct, Emerald and other academic databases were used to search relevant studies relating to casino and gambling research streams. Findings The review identifies several research gaps on the basis of the SPC link. Specifically, internal service quality needs more attention from both the practice and research points of view. Casino employee research should be extended to include personal traits and characteristics that may contribute to employee performance and loyalty. In the interaction between casino service providers and gamblers, more studies should be undertaken on the efficiency and effectiveness of marketing initiatives and promotions. Externally, the paper points out that more appropriate measurement of customer loyalty and casino profitability should be explored. Research limitations/implications This review provides references to focusing on key competitive advantages and presents guidelines on improving business growth and profitability for casino managers. The paper also identifies research areas that future studies should attend to. Originality/value The paper is the first thorough literature review of gaming research on marketing and management with a focus on the SPC model. This review represents a new era of gaming research, extending the problem gambling research focus into a broader scope embracing other disciplines.

This study investigates Generation Y employees' career choices and selection criteria as well as the underlying needs each criterion fulfills. A career choice ladder is presented to conceptualize the hierarchical nature of the criteria and career needs. This study also explores the relationship of the meaning of work to Generation Y employees' career choices and how it may influence their commitment outcomes. It adopts a longitudinal qualitative inquiry approach. This study bridges the gap in the literature between employee motivation and career/job choices. It offers a fuller understanding of the specific attributes and dimensions of career choices and their interrelationship with employee motivations.

Mindfulness has received considerable attention over the past few years in prior psychology literature. However, the role of mindfulness has yet to receive sufficient attention in the service sector, especially the casino service sector. The objective of the current study is to examine whether casino frontline employees’ perceptions of surface acting mediate the relationship between mindfulness and emotional exhaustion and to investigate the moderating role of a climate of authenticity in the process of their formation of emotional exhaustion. Hierarchical linear modeling results indicate that casino frontline employees’ perceived mindfulness has a significant negative influence on their surface acting, which ultimately has a significant positive effect on their emotional exhaustion. In addition, the significant positive association between surface acting and emotional exhaustion is moderated by the authentic climate. A higher degree of authenticity within the climate weakens the positive impact of surface acting on casino employees’ emotional exhaustion.

Families seek vacations as a means to improve family interaction and cohesion. Research on the effects of smartphones and other technology on the tourist experience has gained traction in recent years. Unfortunately, there still remains a void in understanding the role smartphones have on interaction and relationship dynamics during family vacations. Therefore, a qualitative research approach was employed to understand the extent to which smartphone usage influences the family vacation experience. The findings revealed that families relied on smartphones to foster a sense of family unity and retain a sense of individuality. Second, smartphones mediated families’ experience of a destination. Third, smartphones altered the traditional internalization and recollection process of family vacation memories.

This exploratory study challenges the predominant static view of travel motivation by providing new insights into the link between travel motivations and behaviors. It assesses when and how tourist travel motives change over time. It further explores the mediating role of travel involvement and the moderating role of economic performance using the time-variant travel motivational framework as a longitudinal, multilevel model. This study advances the literature by demonstrating that travel motivations and their effects on tourist travel involvement and behaviors vary over time, and that such a variation can be explained by the changes in economic conditions. In essence, this study sheds light on the traditional view of travel motivation and builds a dynamic multilevel model of pleasure travel motivation and behavior.

Purpose The aim of this study is to understand the knowledge-sharing structure and co-production of trip-related knowledge through online travel forums. Design/methodology/approach The travel forum threads were collected from TripAdvisor’s Sydney travel forum for the period from 2010 to 2014, which contains 115,847 threads from 8,346 conversations. The data analytical technique was based on a novel methodological approach – visual analytics, including semantic pattern generation and network analysis. Findings Findings indicate that the knowledge structure is created by community residents who camouflage as local experts and serve as ambassadors of a destination. The knowledge structure presents collective intelligence co-produced by community residents and tourists. Further findings reveal how these community residents associate with each other and form a knowledge repertoire with information covering various travel domain areas. Practical implications The study offers valuable insights to help destination-management organizations and tour operators identify existing and emerging tourism issues to achieve a competitive destination advantage. Originality/value This study highlights the process of social media mediated travel knowledge co-production. It also discovers how community residents engage in reaching out to tourists by camouflaging as ordinary users.

Wetland utilization generates economic savings: because they rely on more natural methods, they are less expensive to build and operate than conventional sewage treatment. Furthermore, the purified water is suitable for reuse. Purified water for reuse is a very valuable asset as clean water is a scarce resource that is critical for human existence, to focus on preserving or constructing manmade wetlands in order to increase water availability over time and gain benefits from the ecosystem services provided. Wetlands for wastewater treatment can be used for a wide variety of applications, including: • Domestic sewage treatment • Agricultural washings, wastewaters and field runoff buffers • Industrial effluents and yard runoff filtration • Group housing and municipal sewage schemes and sludge disposal • Landfill runoff and other long-term low maintenance situations • Urban and road storm-water runoff, for both flow buffering and water filtration • Mine tailings and metal reclamation • Stream, river and lake restoration • Recreational and amenity applications • Flood control and habitat enhancement

Objective The CYP2C19 loss-of-function (LoF) allele is present in half of the East Asian population and is associated with high on-treatment platelet reactivity (HTPR). This study aimed to investigate whether a rapid genotyping-guided approach is feasible and efficacious for selecting P2Y12 receptor blockers in Chinese patients suffering from acute coronary syndrome (ACS). Methods This was a single-centre, prospective, randomized, open-label study. A total of 132 patients with ACS were randomized to the rapid genotyping-guided treatment group (GG, N = 65) or the standard treatment group (SG, N = 67). Patients in the GG group were genotyped by the Verigene system. Patients with the CYP2C19 LoF allele were switched to ticagrelor and all remaining patients continued on clopidogrel. The endpoints were HTPR at 24 hours after the first loading dose of clopidogrel and 1 month afterwards. Results Forty patients in the GG group switched to ticagrelor, while others continued on clopidogrel. The incidence of HTPR in the GG vs SG groups was 9.2% vs 40.3% at 24 hours and 6.5% vs 32.3% at 1 month, respectively. Rapid point-of-care genotyping showed 100% concordance with conventional genotyping by real-time polymerase chain reaction. Conclusions In Chinese patients suffering from ACS, the rapid genotyping-guided approach for selecting P2Y12 receptor blockers is feasible and reduces the incidence of HTPR. Clinical Trial Registration URL: http://clinicaltrials.gov . Unique identifier: NCT01994941.

Renal cell carcinoma is the seventh most common cancer in the United States, and its metastatic form has a very poor prognosis due to a lack of effective treatment and thorough understanding on metastatic mechanism. This chapter will demonstrate a novel concept that intratumoral heterogeneity is essential for metastasis in renal cell carcinoma. We will first introduce the in vitro system and the mouse model that led to the finding of the cooperative mechanism for metastasis. Then, the results from the CAM model illustrate the cooperative interactions that lead to metastasis also occur in this model. We believe that the CAM model, as a unique and sustainable system, can open up new opportunities to study the metastatic disease.

Significance This manuscript describes a precise diel cycle carried out by airborne microbiota in the tropics. 795 metagenomes from air samples taken from a single site show that fungi, bacteria, and plants all adhere to a specific timing for their presence in the near-surface atmosphere. The airborne community composition thereby shows an unexpected robustness, with the majority of the dynamics in taxa composition occurring within 24 h, but not across days, weeks, or months. Environmental parameters are the main drivers for the observed phenomenon, with temperature being the most important one., The atmosphere is vastly underexplored as a habitable ecosystem for microbial organisms. In this study, we investigated 795 time-resolved metagenomes from tropical air, generating 2.27 terabases of data. Despite only 9 to 17% of the generated sequence data currently being assignable to taxa, the air harbored a microbial diversity that rivals the complexity of other planetary ecosystems. The airborne microbial organisms followed a clear diel cycle, possibly driven by environmental factors. Interday taxonomic diversity exceeded day-to-day and month-to-month variation. Environmental time series revealed the existence of a large core of microbial taxa that remained invariable over 13 mo, thereby underlining the long-term robustness of the airborne community structure. Unlike terrestrial or aquatic environments, where prokaryotes are prevalent, the tropical airborne biomass was dominated by DNA from eukaryotic phyla. Specific fungal and bacterial species were strongly correlated with temperature, humidity, and CO2 concentration, making them suitable biomarkers for studying the bioaerosol dynamics of the atmosphere.

Penicillium oxalicum strain SGAir0226 was isolated from a tropical air sample collected in Singapore. The complete genome was assembled from long reads obtained from single-molecule real-time sequencing and was further polished and error corrected using short read sequencing data. The assembly comprises 20 contigs with a total length of 30.7 Mb. The genome was predicted to contain 8310 protein-coding genes, 237 tRNAs and 83 rRNAs.

The complete genome sequence of Rhodococcus sp. strain SGAir0479 is presented here. This organism was isolated from an air sample collected in an indoor location in Singapore. The consensus assembly generated one chromosome of 4.86 Mb (G+C content of 69.8%) and one plasmid of 104,493 bp.

Lysinibacillus sp. strain SGAir0095 was isolated from tropical air samples collected in Singapore, and its complete genome was sequenced with a hybrid strategy using single-molecule real-time sequencing and short reads. The genome consists of one chromosome of 4.14 Mbp and encompasses 3,885 protein-coding genes, 39 rRNAs, and 101 tRNAs.

The Pontibacter bacterial genus has been detected in marine and soil environments. Here, we report the genome sequence of Pontibacter sp. strain SGAir0037, which was isolated from outdoor air samples collected in Singapore. The genome comprises one chromosome of 5.26 Mb and one plasmid of 127 kb.

The Pontibacter bacterial genus has been detected in marine and soil environments. Here, we report the genome sequence of Pontibacter sp. strain SGAir0037, which was isolated from outdoor air samples collected in Singapore. The genome comprises one chromosome of 5.26 Mb and one plasmid of 127 kb.

Pseudomonas sp. strain SGAir0191 was isolated from an air sample collected in Singapore, and its genome was sequenced using a combination of long and short reads to generate a high-quality genome assembly. The complete genome is approximately 5.07 Mb with 4,370 protein-coding genes, 19 rRNAs, and 73 tRNAs.

Microbacterium sp. strain SGAir0570 was isolated from air samples collected in Singapore. Its genome was assembled using single-molecule real-time sequencing and MiSeq short reads. It has one chromosome with a length of 3.38 Mb and one 59.2-kb plasmid. It contains 3,170 protein-coding genes, 48 tRNAs, and 6 rRNAs.

Enterococcus faecalis strain SGAir0397 was isolated from a tropical air sample collected in Singapore. Its genome was assembled using single-molecule real-time sequencing data and comprises one circular chromosome with a length of 2.69 Mbp. The genome contains 2,595 protein-coding genes, 59 tRNAs, and 12 rRNAs.

Agrococcus sp. strain SGAir0287 was isolated from tropical air samples collected in Singapore. Assembled using single-molecule real-time (SMRT) sequencing and MiSeq reads, the genome consists of one circular chromosome of 3,084,767 bp. The entire genome has 2,870 protein-coding genes, 45 tRNAs, and 3 rRNAs.

Brachybacterium sp. strain SGAir0954 was isolated from tropical air collected in Singapore, and its genome was sequenced and assembled using long reads generated by single-molecule real-time (SMRT) sequencing. The complete genome has a size of 3.41 Mb and consists of 2,955 protein coding genes, 50 tRNAs, and 9 rRNAs.

Acinetobacter indicus (Gammaproteobacteria) is a strict aerobic nonmotile bacterium. The strain SGAir0564 was isolated from air samples collected in Singapore. The complete genome is 3.1 Mb and was assembled using a combination of short and long reads. The genome contains 2,808 protein-coding genes, 80 tRNAs, and 21 rRNA subunits.

Lelliottia nimipressuralis type strain SGAir0187 was isolated from tropical air samples collected in Singapore. The genome was assembled with an average coverage of 180-fold using Pacific Biosciences long reads and Illumina MiSeq paired-end reads. The genome measures 4.8 Mb and contains 4,424 protein-coding genes, 83 tRNAs, and 25 rRNAs.

The associated article was published under the title Genome Announcements (ISSN: 2169-8287). In July 2018, Genome Announcements was renamed Microbiology Resource Announcements. Volume 6, no. 22, e00424-18, 2018, [https://doi.org/10.1128/genomeA.00424-18][1]. Page 1: The title should appear as given

Brevundimonas sp. strain SGAir0440 was isolated from indoor air samples collected in Singapore. Its genome was assembled using single-molecule real-time sequencing data, resulting in one circular chromosome with a length of 3.1 Mbp. The genome consists of 3,033 protein-coding genes, 48 tRNAs, and 6 rRNA operons.

Bacillus altitudinis strain SGAir0031 (Firmicutes) was isolated from tropical air samples collected in Singapore. Its genome was assembled using short reads and single-molecule real-time sequencing, comprising one chromosome with 3.81 Mb and one plasmid with 32 kb. The genome consists of 3,820 protein-coding genes, 81 tRNAs, and 24 rRNAs.

The associated article was published under the title Genome Announcements (ISSN: 2169-8287). In July 2018, Genome Announcements was renamed Microbiology Resource Announcements. Volume 6, no. 19, e00229-18, 2018, [https://doi.org/10.1128/genomeA.00229-18][1]. Page 1: The title should appear as given

A magnesium hydride cation [(L)MgH]

Curtobacterium sp. strain SGAir0471 was isolated from tropical air samples collected in Singapore. The genome was assembled using PacBio RS II long reads and Illumina MiSeq short paired-end reads. The complete genome measures 3.53 Mb and consists of 3,151 protein-coding genes, 49 tRNAs, and 12 rRNAs.

Nissabacter sp. strain SGAir0207 was isolated from a tropical air sample collected in Singapore. Its genome was assembled using a hybrid approach with long and short reads, resulting in one chromosome of 3.9 Mb and 7 plasmids. The complete genome consists of 4,403 protein-coding, 84 tRNA, and 22 rRNA genes.

Citricoccus sp. strain SGAir0253 was isolated from indoor air collected in Singapore. Its genome sequence was assembled using single-molecule real-time sequencing. It comprises one chromosome of 3.32 Mb and two plasmids of 137 kb and 99 kb. The genome consists of 2,950 protein-coding genes, 49 tRNAs, and 9 rRNAs.

Lysinibacillus sp. strain SGAir0095 was isolated from tropical air samples collected in Singapore, and its complete genome was sequenced with a hybrid strategy using single-molecule real-time sequencing and short reads. The genome consists of one chromosome of 4.14 Mbp and encompasses 3,885 protein-coding genes, 39 rRNAs, and 101 tRNAs.

Micrococcus luteus strain SGAir0127 was isolated from indoor air samples collected in Singapore. The assembly, based on single-molecule real-time sequencing reads, resulted in two contigs, one chromosomal contig with a length of 2.57 Mbp and one nonchromosomal contig of 8.68 kbp. The genome has a total of 2,564 genes.

Streptomyces sp. strain SGAir0924 was isolated from outdoor air collected in Singapore. Its genome was assembled using long reads generated by single-molecule real-time sequencing. The final assembly had one chromosome of 7.65 Mb and three plasmids with an average length of 142 kb. The genome contained 6,825 protein-coding genes, 68 tRNAs, and 18 rRNAs.

The complete genome sequence of Rhodococcus sp. strain SGAir0479 is presented here. This organism was isolated from an air sample collected in an indoor location in Singapore. The consensus assembly generated one chromosome of 4.86 Mb (G+C content of 69.8%) and one plasmid of 104,493 bp.

This study aims to reconcile two contrasting research perspectives on tourist decision making. The first perspective contends that tourists are constrained with limited resources and are inhibited to travel, whereas the second perspective contends that tourists search for means to develop a career in traveling and are thereby intrigued to travel to more destinations. This study employs a multilevel design by assessing the relationships of tourist travel frequencies among three outbound markets, namely, in-state, out-of-state domestic, and international markets, through a longitudinal study. By modeling a situational factor—unemployment rate—at the macro level, this study reveals a significant cross-level moderating effect on the relationship between the travel frequencies of domestic and international markets. The findings not only reveal which of these two perspectives is more applicable at a particular situation but also enrich the theories germane to travel career, destination choice, and distance decay.

Academics and practitioners are increasingly interested in how branding and service may affect consumer behaviors. In view of intensifying competition in the casino industry, understanding these relationships would help casino operators achieve competitive advantage. The current study draws on the relevant marketing literature, and examines the antecedents, moderators and consequences of consumer buying behaviors, with a focus on impulsive buying in the casino settings. The proposed antecedents are casino service environment and employee service. Customer brand attachment and loyalty behaviors are modeled as consequences, and casino brand equity as a cross-level moderator. A quantitative method was employed for the purpose of this study. The survey was undertaken at 22 major casinos in Macau through a multilevel design. Results show that the casino service environment indeed induces impulsive gambling. Whilst employee service has little influence on impulsive gambling, the effect is enhanced by casino brand equity. Employee service is particularly salient for casinos with low brand equity. Impulsive gambling does have significant influence on loyalty outcomes through the mediating effect of brand attachment. Brand equity also demonstrates cross-level linear and nonlinear effects on the chain relationship, with the linear effect significantly larger. Implications for practitioners and the literature are provided to conclude the paper.

Tourism research often encounters social phenomena and research problems that involve multiple levels. However, most researchers assume that the phenomena exist in a single level and perform analyses that do not reflect the hierarchical nature of social dynamics. This article heeds the call from Current Issues in Tourism by illustrating multilevel methods and proposing an agenda for multilevel research. In particular, this article seeks to reconcile the limitations of single-level analysis and to delineate how multilevel methods could be applied in tourism research. It further seeks to advance tourism theories by introducing more complex multilevel design with broader applications in various tourism settings. This article presents two common tourism research scenarios, critiques their limitations, and proposes how multilevel methods could not only address these limitations, but also how they could advance tourism theories. An empirical study is offered to demonstrate multilevel design and analytical techn...