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204. 90th Annual Convention Poster Presentations and Abstracts

Author

Ellis, C. N., Coyle, D. J., Boggs, H. W., Slagle, G. W., Cole, P. A., Kuramoto, S., Ihara, O., Oohara, T., Nichols, J., Opelka, F., Gathright, J. B., Green, J. B., Poulard, J. B., Ott, A., Bank, S., Margolis, I. B., Meagher, A., Stuart, M., Heine, J. A., Rothenberger, D. A., Nemer, F. D., Christenson, C. E., Saad, R. C., Church, J. M., Fazio, V. W., Lavery, I. C., Oakley, J. R., Milsom, J. W., Schroeder, T. K., Påhlman, L., Frykholm, G., Glimelius, B., Kashtan, H., Papa, M., Wilson, B., Stern, H., Zelnick, R., Haas, P., Ajlouni, M., Fox, T., Szilagy, E., Cummings, B. J., Fleshman, J. W., Dreznick, Z., Fry, R. D., Kodner, I. J., Perry, R. E., Pemberton, J. H., Litchy, W. L., Ferrara, A., Levin, K. E., Hanson, R. B., Cali, R. L., Blatchford, G. J., Thorson, A. G., Christenson, M. A., Pitsch, R. M., Jensen, L. L., Lowry, A. C., Keighley, M. R. B., Oya, M., Oritz, J., Pinho, M., Asperer, J., Chattaphaday, G., Baeten, C., Konsten, J., Spaans, F., Soeters, P., Habets, A., Schouten, W. R., Ruseler van Embden, J. G. H., Auwerda, J. J. A., Sagar, P. M., Goodwin, P., Holdsworth, P. J., Johnston, D., Bundy, C. A., Jacobs, D. M., Bubrick, M. P., Kashiwagi, H., Konishi, F., Kanazawa, K., Woodland, D. O., Saclarides, T. J., Bapna, M. S., Kubota, Y., Sunouchi, K., Ono, M., Muto, T., Masaki, T., Suzuki, K., Adachi, M., Wong, W. D., Goldberg, S. M., Wexner, S. D., Daniel, N., Jagelman, D. G., Christiansen, J., Rasmussen, O., Zhu, B. -W., Williams, J. G., Schottler, J. L., Heyman, S., Marchetti, F., Timmcke, A. E., Hicks, T. C., Ray, J. E., Bernstein, M. A., Madoff, R. D., Caushaj, P. F., Zarbo, R. J., Ma, C. K., Shida, H., Yamamoto, T., Machida, T., Imanari, T., Wang, J. Y., You, Y. T., Tang, R. P., Chen, J. S., Chang-Chien, C. R., Sugihara, K., Hojo, K., Moriya, Y., Hasegawa, H., Krueger, B., Warren, W., Faber, L. P., Abel, M. E., Chiu, Y. S. Y., Russell, T. R., Volpe, P. A., Frazee, R. C., Roberts, J., Symmonds, S., Snyder, S., Hendricks, J., Smith, R., Merchant, N., Hashmi, H., Scalea, T., Whelan, R., Longo, W. E., Gusberg, B. J., Ballantyne, G. H., Davidson, T., Allen-Mersh, T. G., Gazzard, B., Miles, A. J. G., Wastell, C., Viponde, M., Stotter, A., Miller, R. F., Fieldman, N., Slack, W. W., Tjandra, J., Savoca, P. E., Flannery, J. T., Modlin, I. M., Tsukada, K., Tazawa, K., Lavery, E. C., Voeller, G. R., Bunch, G., Britt, L. G., Neto, J. A. Reis, Quilici, F. A., Cordeiro, F., Reis, Jr, J. A., Wojcik, J. B., Banerjee, S. R., Walters, D. L., Cherry, D. A., Bleday, R., Pena, J. P., Buls, J. G., Pascual, R., Tripodi, G., Padmanabhan, A., Schouter, W. R., Blankensteijn, J. D., Moenning, S., Huber, P., Simonton, C., Odom, C., Kaplan, E., Nightengale, S., Shah, P. C., Hashami, H. F., Kottmeier, P., Velcek, F., Klotz, D., Whelan, R. L., Sher, M. E., Bauer, J. J., Gelernt, I., Launer, D. P., Gerber, A., Nogueras, J. J., Finne, C. O., Sohn, N., Weinstein, M. A., Lugo, R. N., Eisenberg, M. M., Tsao, J., Galandiuk, S., Tuckson, W. B., Strong, S., Oakey, J. R., Ambroze, W. L., Dozois, R. R., Carpenter, H. A., Kartheuser, A. H., LaRusso, N. F., Wiesner, R. H., Ilstrup, D. M., Schleck, C. D., Ambroze, W., Beart, R., Dozois, R., Wolff, B., Pemberton, J., Kelly, K., Devine, R., Nivatvongs, S., Metzger, P., Phillips, S. F., Zinmeister, A. R., Pezim, M. E., Vignati, P., Cohen, J., Stahl, T. J., Roberts, P. L., Schoetz, Jr., D. J., Murray, J. J., Coller, J. A., Veidenheimer, M. C., Yamazaki, Y., Ribeiro, M. B., Sachar, D., Heimann, T. M., Aufses, A. H., Greenstein, A. J., Stryker, S. J., Green, D., McLeod, R. S., Cohen, Z., Cullen, J., Greenberg, G. R., Ho, C. S., Reznick, R., Wolff, B. G., Cangemi, J., Carryer, P., Jeejeebhoy, K. N., MacCarty, R., Weilland, L., Senagore, A. J., MacKeigan, J. M., Guillem, J., Ondrula, D. P., Prasad, M. L., Nelson, R. L., Abcarian, H., Coughlin, R. J., Corman, M. L., Prager, E. D., Borison, D. I., Bloom, A. D., Pritchard, T. J., McGannon, E., Sivak, M. V., van Stolk, R., Hull-Boiner, S., Milson, J. W., Sullivan, M., Rosato, G. O., Jorge, J. M., Durdey, P., Kennedy, M. J., Oster, M., Murray, J., Cirocco, W. C., Rusin, L. C., Brown, A. C., Reilly, J. C., Cataldo, P., Luchtefeld, M. A., Mazier, W. P., Wolkomir, A. F., Ruiz-Moreno, F., Alvarado-Cerna, R., Rodriguez, U., Amaro, J., Kerner, B. A., Oliver, G. C., Eisenstat, T. E., Rubin, R. J., Salvati, E. P., Dominguez, J. M., Coon, J. S., Weinstein, R. S., Kameyama, M., Fukuda, I., Imaoka, S., Iwanga, T., Kyzer, S., Mitmaker, B., Gordon, P. H., Wang, E., Grace, R. H., Gibbons, P., Scott, K. M. W., Berger, A., Mischinger, H. J., Arian-Schad, K., Davis, M., Miller, D., Fielding, L. P., Begin, L. R., Bell, A. M., Shafik, A., Abdel-Moneim, K., Khalid, A., Devine, R. M., Beart, Jr., R. W., Melton, L. J., Ngoi, S. S., Chia, J., Goh, P., Sim, E., Godwin, P., Quirke, P., Barrett, R. C., Koltun, W. A., Smith, R. J., Loehner, D., Roberts, P., Veidenheimer, M., Schoetz, D., Chattopadhyay, G., Kumar, D., Hosie, K., Kmiot, W., Mostaf, A., Tulley, N., Harding, I., Falcone, R. E., Wanamaker, S., Santanello, S. A., Carey, L. C., Rivera, D. E., Durdley, P., Gross, P. T., Sarles, J. C., Arnaud, A., Sielezneff, I., Orsoni, P., Joly, A., Limberg, B., Stolfi, V. M., Lavery, I., Oakley, J., Church, J., Fazio, V., Asbun, H. J., Castellanos, H., Asbun, J., Franko, E. R., Ivatury, R. R., Schwalb, D., Saad, R., Schroeder, T., Reis, Jr., J. A., Dziki, A. J., Duncan, M. D., Harmon, J. W., Saini, N., Malthaner, R. A., Fernicola, M. T., Hakki, F. Z., Trad, K. S., Ugarte, R. M., Ryan, P., Chang, H. R., Chavoshan, B., Barsoum, G., Bonardi, R., Scaramelo, A., Possebon, A., Peres, C., Röhrig, C., Kappas, A. M., Ortiz, J., Fan, H. A., Milsom, J., Lechner, P., Lind, P., Cesnik, H., Venkatesh, K. S., Larson, D. M., Morrison, D. N., Ramanujam, P. J., Rubbini, M., Mascoli, F., Mari, C., Bresadola, V., and Donini, I.

Published
1991
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215. Clinical and molecular findings in a cohort of ANO5‐related myopathy

Author

Silva, André M. S., primary, Coimbra-Neto, Antônio R., additional, Souza, Paulo Victor S., additional, Winckler, Pablo B., additional, Gonçalves, Marcus V. M., additional, Cavalcanti, Eduardo B. U., additional, Carvalho, Alzira A. D. S., additional, Sobreira, Cláudia F. D. R., additional, Camelo, Clara G., additional, Mendonça, Rodrigo D. H., additional, Estephan, Eduardo D. P., additional, Reed, Umbertina C., additional, Machado-Costa, Marcela C., additional, Dourado-Junior, Mario E. T., additional, Pereira, Vanessa C., additional, Cruzeiro, Marcelo M., additional, Helito, Paulo V. P., additional, Aivazoglou, Laís U., additional, Camargo, Leonardo V. D., additional, Gomes, Hudson H., additional, Camargo, Amaro J. S. D., additional, Pinto, Wladimir B. V. D. R., additional, Badia, Bruno M. L., additional, Libardi, Luiz H., additional, Yanagiura, Mario T., additional, Oliveira, Acary S. B., additional, Nucci, Anamarli, additional, Saute, Jonas A. M., additional, França-Junior, Marcondes C., additional, and Zanoteli, Edmar, additional

Published
2019
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224. Nuclear dependence of the 2p2h electroweak response in the Relativistic Fermi Gas model

Author

Maria Benedetta Barbaro, Amaro, J. E., Caballero, J. A., Pace, A., Donnelly, T. W., Megías, G. D., and Simo, I. Ruiz

Subjects
Condensed Matter::Quantum Gases, Nuclear Theory (nucl-th), Nuclear Theory, FOS: Physical sciences, Condensed Matter::Strongly Correlated Electrons, Nuclear Experiment
Abstract

We present the results of a recent study of meson-exchange two-body currents in lepton-nucleus inclusive scattering at various kinematics and for different nuclei within the Relativistic Fermi Gas model. We show that the associated nuclear response functions at their peaks scale as $A k_F^2$, for Fermi momentum $k_F$ going from 200 to 300 MeV/c and momentum transfer $q$ from $2k_F$ to 2 GeV/c. This behavior is different from what is found for the quasielastic response, which scales as $A/k_F$. This result can be valuable in the analyses of long-baseline neutrino oscillation experiments, which need to implement these nuclear effects in Monte Carlo simulations for different kinematics and nuclear targets., Comment: 11 pages, 6 figures, Proccedings of the Workshop "Advanced Aspects in Nuclear Structure and Reactions at Different Energy Scales", 25-28 April 2017, Arbanasi, Bulgaria

Published
2017

225. Electron- versus neutrino-nucleus scattering.

Author

Amaro, J E, Barbaro, M B, Caballero, J A, González-Jiménez, R, Megias, G D, and Simo, I Ruiz

Subjects
*NEUTRINO scattering, *INELASTIC scattering, *NUCLEAR models, *ELECTRON scattering, *NEUTRINO interactions, *FORECASTING, *NEUTRINOS
Abstract

We illustrate the connection between electron and neutrino scattering off nuclei and show how the former process can be used to constrain the description of the latter. After reviewing some of the nuclear models commonly used to study lepton-nucleus reactions, we describe in detail the SuSAv2 model and show how its predictions compare with the available electron- and neutrino-scattering data over the kinematical range going from the quasi-elastic peak to pion-production and highly inelastic scattering. [ABSTRACT FROM AUTHOR]

Published
2020
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230. INCREASED FUNCTIONAL CONNECTIVITY AFTER LISTENING TO FAVORED MUSIC IN ADULTS WITH ALZHEIMER DEMENTIA

Author

King, J.B., primary, Jones, K.G., additional, Goldberg, E., additional, Rollins, M., additional, MacNamee, K., additional, Moffit, C., additional, Naidu, S.R., additional, Ferguson, M.A., additional, Garcia-Leavitt, E., additional, Amaro, J., additional, Breitenbach, K.R., additional, Watson, J.M., additional, Gurgel, R.K., additional, Anderson, J.S., additional, and Foster, N.L., additional

Published
2018
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231. Charged-Current Quasielastic (Anti)Neutrino Cross Sections on 12C with Realistic Spectral Functions Including Meson-Exchange Contributions.

Author

Ivanov, M. V., Antonov, A. N., Megias, G. D., Caballero, J. A., Barbaro, M. B., Amaro, J. E., Simo, I. Ruiz, Donnelly, T. W., and Udías, J. M.

Subjects
QUASI-elastic scattering, NEUTRINOS, NUCLEAR cross sections, CARBON isotopes, MESONS, SPECTRUM analysis
Abstract

We present a detailed study of charged-current quasielastic (anti)neutrino scattering cross sections on a 12C target obtained using a spectral function S (p, ε) that gives a scaling function in accordance with the electron scattering data. The spectral function accounts for the nucleon-nucleon (NN) correlations, it has a realistic energy dependence and natural orbitals (NO’s) from the Jastrow correlation method are used in its construction. The results are compared with those when NN correlations are not included, namely harmonic-oscillator single-particle wave functions are used instead of NO’s. A comparison of the results with recent experiments, as well as to results from the superscaling approach is done. The contribution of two-particle two-hole meson-exchange currents on neutrino–nucleus interactions is also considered within a fully relativistic Fermi gas. The results show a good agreement with the experimental data over the whole range of neutrino energies. [ABSTRACT FROM AUTHOR]

Published
2019
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235. Density dependence of 2p-2h meson-exchange currents

Author

Massachusetts Institute of Technology. Center for Theoretical Physics, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Donnelly, T William, Amaro, J. E., Barbaro, M. B., Caballero, J. A., De Pace, A., Megias, G. D., Ruiz Simo, I., Massachusetts Institute of Technology. Center for Theoretical Physics, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Donnelly, T William, Amaro, J. E., Barbaro, M. B., Caballero, J. A., De Pace, A., Megias, G. D., and Ruiz Simo, I.

Abstract

United States. Department of Energy (DE-FC02-94ER40818)

Published
2017

236. Charged-current neutrino-nucleus reactions within the superscaling meson-exchange current approach

Author

Massachusetts Institute of Technology. Center for Theoretical Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Donnelly, T William, Megias, G. D., Amaro, J. E., Barbaro, M. B., Caballero, J. A., Simo, I. Ruiz, Massachusetts Institute of Technology. Center for Theoretical Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Donnelly, T William, Megias, G. D., Amaro, J. E., Barbaro, M. B., Caballero, J. A., and Simo, I. Ruiz

Abstract

We present a detailed study of charged-current neutrino-nucleus reactions in a fully relativistic framework and comparisons with recent experiments spanning an energy range from hundreds of MeV up to 100 GeV within the superscaling approach, which is based on the analysis of electron-nucleus scattering data and has been recently improved with the inclusion of relativistic mean field theory effects. We also evaluate and discuss the impact of two-particle two-hole meson-exchange currents on neutrino-nucleus interactions through the analysis of two-particle two-hole axial and vector contributions to weak response functions in a fully relativistic Fermi gas. The results show a fairly good agreement with experimental data over the whole range of neutrino energies., Spain. Dirección General de Investigación Científica y Técnica, Fonds Europeen de Developpement Economique et Regional (Grants FIS2014-59386-P and FIS2014-53448-C2-1), Agencia de Innovacion y Desarrollo de Andalucia (Grants FQM225 and FQM160), Istituto nazionale di fisica nucleare (INFN) (Project MANYBODY), United States. Dept. of Energy (Cooperative Agreement DE-FC02-94ER40818)

Published
2017

243. Culture and the Anxiety Disorders: Recommendations for DSM-V

Author

Roberto Lewis-Fernández, Dan J. Stein, Devon E. Hinton, Stefan G. Hofmann, B A Betty Liao, Elissa H. Patterson, Michelle G. Craske, Anu Asnaani, and Amaro J. Laria

Subjects
Nosology, medicine.medical_specialty, Generalized anxiety disorder, media_common.quotation_subject, Culture, Guidelines as Topic, Article, Prevalence of mental disorders, Epidemiology, medicine, Humans, Psychiatry, media_common, Panic disorder, Social anxiety, Classification of mental disorders, medicine.disease, Anxiety Disorders, Mental health, Diagnostic and Statistical Manual of Mental Disorders, Psychiatry and Mental health, Clinical Psychology, Anxiety, Worry, medicine.symptom, Psychology, Anxiety disorder, Clinical psychology
Abstract

Background: The anxiety disorders specified in the fourth edition, text revision, of The Diagnostic and Statistical Manual (DSM-IV-TR) are identified universally in human societies, and also show substantial cultural particularities in prevalence and symptomatology. Possible explanations for the observed epidemiological variability include lack of measurement equivalence, true differences in prevalence, and limited validity or precision of diagnostic criteria. One central question is whether, through inadvertent “over-specification” of disorders, the post-DSM-III nosology has missed related but somewhat different presentations of the same disorder because they do not exactly fit specified criteria sets. This review canvases the mental health literature for evidence of cross-cultural limitations in DSM-IV-TR anxiety disorder criteria. Methods: Searches were conducted of the mental health literature, particularly since 1994, regarding cultural or race/ethnicity-related factors that might limit the universal applicability of the diagnostic criteria for six anxiety disorders. Results: Possible mismatches between the DSM criteria and the local phenomenology of the disorder in specific cultural contexts were found for three anxiety disorders in particular. These involve the unexpectedness and 10-minute crescendo criteria in Panic Disorder; the definition of social anxiety and social reference group in Social Anxiety Disorder; and the priority given to psychological symptoms of worry in Generalized Anxiety Disorder. Limited evidence was found throughout, particularly in terms of neurobiological markers, genetic risk factors, treatment response, and other DSM-V validators that could help clarify the cross-cultural applicability of criteria. Conclusions :O n the basis of the available data, options and preliminary recommendations for DSM-V are put forth that should be further evaluated and tested. (This Article is being co-published by Depression & Anxiety and the American Psychiatric Association. This Article first appeared in

Published
2011
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244. THE EFFECT OF PROSPECTIVE HLA-A AND -B MATCHING IN 288 PENETRATING KERATOPLASTIES FOR HERPES SIMPLEX KERATITIS

Author

C. C. Kok-Van Alphen, H. J. M. Völker-Dieben, P. De Lange, and D'Amaro J

Subjects
Adult, Graft Rejection, Male, medicine.medical_specialty, Adolescent, medicine.medical_treatment, medicine.disease_cause, Keratitis, Cornea, Corneal Transplantation, HLA Antigens, Recurrence, Ophthalmology, medicine, Humans, Child, Survival rate, Corneal transplantation, Aged, Retrospective Studies, HLA-A Antigens, business.industry, Histocompatibility Testing, Graft Survival, Retrospective cohort study, General Medicine, Keratitis, Dendritic, Middle Aged, medicine.disease, eye diseases, Surgery, HLA-A, surgical procedures, operative, Herpes simplex virus, medicine.anatomical_structure, Penetrating Keratoplasties, HLA-B Antigens, Child, Preschool, Female, sense organs, business
Abstract

A retrospective review of 288 penetrating keratoplasties (PKP) for herpes simplex keratitis demonstrated a 60.4% survival rate of clear grafts at 3 years. A highly significant difference in corneal graft survival in severely vascularized corneas (57.1% at 3 years) versus non- or slightly vascularized corneas (82.8% at 3 years) was observed (P = 0.009). Prospectively HLA-A and -B matched grafts in vascularized corneas revealed a significantly improved graft survival when compared to unmatched grafts (P = 0.035). Corneal graft survival in eyes grafted 'à chaud' was not significantly below the graft survival of vascularized corneas with a clinically non-active herpetic corneal disease. Recurrence of herpes simplex in the graft was observed in an earlier postoperative period in HLA-A and -B matched grafts (P = 0.0004).

Published
2009
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245. DR Typing in Australian Aborigines. An Indication for a Second Locus in the HLA-D Region Defined by Serology

Author

B.A. Bradley, D'Amaro J, Jon J. van Rood, A. Leeuwen, Annemarie Termijtelen, and B. Boettcher

Subjects
Genetics, education.field_of_study, Native Hawaiian or Other Pacific Islander, Histocompatibility Testing, Immunology, Population, Histocompatibility Antigens Class II, Chromosome Mapping, Locus (genetics), General Medicine, Biology, Biochemistry, Epitope, Serology, Epitopes, Antigen, Humans, Immunology and Allergy, Typing, Allele, education, Antilymphocyte Serum
Abstract

A group of 43 Australian Aborigines was typed for HLA--DR determinants and other antigens on B cells, using pregnancy sera from Caucasoid women. The group could not be considered as random, since a selection was made for an equal number of Au antigen positive and Au antigen negative individuals The typing results showed that the specificities DRw2, 4 and 8 were as well defined in this population as in Caucasoids, whereas the specificities DRw1, 3, 5 and 7 could not be defined. Even more interesting was the finding that a cluster of six sera, defining the local B cell specificity LB12, gave positive reactions in 41 out of 43 Aborigines. Although LB12 is found to be highly associated with DRw1, 2 and 6 in the Caucasoid population, in 36 cases the LB12 positive Aborigines could not be demonstrated to carry the specificities DRw1 or 2. The recognition of DRw6 is difficult at the moment and for the reason its presence or absence in this material is uncertain. However, three individuals typed positive for DRw4 and 8 and for LB12 as well. These findings strongly support the hypothesis that the genes coding for LB12 and its postulated allele LB13 are separate from the genes coding for the known DR determinants. LB12 is very likely identical to the recently described determinants DC1 (Tosi & Tanigaki 1979) and MB1 (Duquesnoy et al. 1979a).

Published
2008
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246. An eight-year study of HLA typing proficiency in Eurotransplant

Author

G. F. J. Hendriks, D'Amaro J, Gmt Schreuder, and G. G. Persijn

Subjects
medicine.medical_specialty, International Cooperation, Immunology, Antigen-Presenting Cells, HLA-C Antigens, Tissue Banks, Human leukocyte antigen, Reference laboratory, Biochemistry, HLA Antigens, Internal medicine, Genetics, medicine, Humans, Immunology and Allergy, Typing, HLA-A Antigens, medicine.diagnostic_test, business.industry, Histocompatibility Testing, Histocompatibility Antigens Class II, HLA-DR Antigens, General Medicine, Kidney Transplantation, Tissue Donors, Europe, Multicenter study, Evaluation Studies as Topic, HLA-B Antigens, Transplanted Organs, business, Tissue typing
Abstract

The main purpose of Eurotransplant, an international organ exchange organisation, is to maximize the survival time of transplanted organs through tissue typing and matching. Regular proficiency testings are necessary to assess the repro-ducibility and the reliability of the HLA typings performed by the individual typing centres. Two different protocols have been used: 1) since 1978, 35 samples of blood and donor spleen were used for cell exchanges (CE) and typed by all participating laboratories; 2) since 1977 samples of donor spleen have been shipped to the reference laboratory in Leiden for retyping (RD) resulting in over 2600 comparable HLA typings. The disrepancy rates of the HLA-A, B, C and DR specificities were analysed over the years. A large number of discrepancies was due to false negative assignments which led to assumed homozygosity at one or more HLA-loci. The recognition of HLA-DR has improved dramatically but with much variation per DR specificity. The concordancy rates for HLA-AB + DR have improved from 40% in 1981 to 91% for CE and 80% for RD typings in 1984. The reproducibility of DR typings in individual laboratories also has improved greatly but there is still considerable variation between the different laboratories.

Published
2008
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247. A search for association of HLA antigens with paranoid schizophrenia: A9 appears as a possible marker

Author

J Dröes, Pavol Ivanyi, D'Amaro J, G.M.Th. Schreuder, and J.J. van Rood

Subjects
Genetic Markers, medicine.medical_specialty, Psychosis, Paranoid schizophrenia, Immunology, Population, Human leukocyte antigen, Biochemistry, Gene Frequency, Antigen, HLA Antigens, Genetics, medicine, Humans, Immunology and Allergy, Psychiatry, education, Association (psychology), education.field_of_study, business.industry, General Medicine, medicine.disease, Phenotype, Relative risk, Schizophrenia, Biological psychiatry, business
Abstract

Sixty-two Dutch patients with the diagnosis paranoid schizophrenia (SCH) were HLA-A-, -B- and -C-typed. An increase in the frequencies of A9 (P = 0.02, relative risk 1.8) and B5 (P = 0.04, relative risk 1.9) was found. Although these correlations do not remain significant after correction for the number of antigens tested, both findings confirm other data from the literature, including the first published report from a population in Sweden. From all hitherto published literature data, the combined relative risks for A9 and B5 is significantly increased. These data strongly indicate that the distribution of HLA antigens among SCH patients is different from the control population.

Published
2008
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