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8,303 results on '"Alarcón P"'

208. Genome-wide association study and polygenic risk scores of retinal thickness across the cognitive continuum: data from the NORFACE cohort

Author

Sáez, María Eugenia, García-Sánchez, Ainhoa, de Rojas, Itziar, Alarcón-Martín, Emilio, Martínez, Joan, Cano, Amanda, García-González, Pablo, Puerta, Raquel, Olivé, Clàudia, Capdevila, Maria, García-Gutiérrez, Fernando, Castilla-Martí, Miguel, Castilla-Martí, Luis, Espinosa, Ana, Alegret, Montserrat, Ricciardi, Mario, Pytel, Vanesa, Valero, Sergi, Tárraga, Lluís, Boada, Mercè, Ruiz, Agustín, and Marquié, Marta

Published
2024
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209. A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death

Author

Minnai, Francesca, Biscarini, Filippo, Esposito, Martina, Dragani, Tommaso A., Bujanda, Luis, Rahmouni, Souad, Alarcón-Riquelme, Marta E., Bernardo, David, Carnero-Montoro, Elena, Buti, Maria, Zeberg, Hugo, Asselta, Rosanna, Romero-Gómez, Manuel, Fernandez-Cadenas, Israel, Fallerini, Chiara, Zguro, Kristina, Croci, Susanna, Baldassarri, Margherita, Bruttini, Mirella, Furini, Simone, Renieri, Alessandra, and Colombo, Francesca

Published
2024
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215. Association of TLR8 Variants in Sex-Based Clinical Differences in Patients with COVID-19

Author

del Carmen Camacho-Rea, María, Martínez-Gómez, Laura Edith, Martinez-Armenta, Carlos, Martínez-Nava, Gabriela Angélica, Ortega-Peña, Silvestre, Olea-Torres, Jessel, Herrera-López, Brígida, Suarez-Ahedo, Carlos, Vázquez-Cárdenas, Paola, Vidal-Vázquez, Rosa P., Ramírez-Hinojosa, Juan Pablo, Vargas-Alarcón, Gilberto, Posadas-Sánchez, Rosalinda, Fragoso, José Manuel, De Jesús Martínez-Ruiz, Felipe, Zayago-Angeles, Dulce María, Mata-Miranda, Mónica Maribel, Vazquez-Zapien, Gustavo Jesús, Martínez-Cuazitl, Adriana, Garcia-Galicia, Armando, Granados, Julio, Ramos, Luis, Rodríguez-Pérez, José Manuel, Pineda, Carlos, and López-Reyes, Alberto

Published
2024
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217. OH as a probe of the warm-water cycle in planet-forming disks

Author

Zannese, Marion, Tabone, Benoît, Habart, Emilie, Goicoechea, Javier R., Zanchet, Alexandre, van Dishoeck, Ewine F., van Hemert, Marc C., Black, John H., Tielens, Alexander G. G. M., Veselinova, A., Jambrina, P. G., Menendez, M., Verdasco, E., Aoiz, F. J., Gonzalez-Sanchez, L., Trahin, Boris, Dartois, Emmanuel, Berné, Olivier, Peeters, Els, He, Jinhua, Sidhu, Ameek, Chown, Ryan, Schroetter, Ilane, Van De Putte, Dries, Canin, Amélie, Alarcón, Felipe, Abergel, Alain, Bergin, Edwin A., Bernard-Salas, Jeronimo, Boersma, Christiaan, Bron, Emeric, Cami, Jan, Dicken, Daniel, Elyajouri, Meriem, Fuente, Asunción, Gordon, Karl D., Issa, Lina, Joblin, Christine, Kannavou, Olga, Khan, Baria, Languignon, David, Le Gal, Romane, Maragkoudakis, Alexandros, Meshaka, Raphael, Okada, Yoko, Onaka, Takashi, Pasquini, Sofia, Pound, Marc W., Robberto, Massimo, Röllig, Markus, Schefter, Bethany, Schirmer, Thiébaut, Vicente, Sílvia, and Wolfire, Mark G.

Published
2024
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226. DES Y3 + KiDS-1000: Consistent cosmology combining cosmic shear surveys

Author

Survey, Dark Energy, Collaboration, Kilo-Degree Survey, Abbott, T. M. C., Aguena, M., Alarcon, A., Alves, O., Amon, A., Andrade-Oliveira, F., Asgari, M., Avila, S., Bacon, D., Bechtol, K., Becker, M. R., Bernstein, G. M., Bertin, E., Bilicki, M., Blazek, J., Bocquet, S., Brooks, D., Burger, P., Burke, D. L., Camacho, H., Campos, A., Rosell, A. Carnero, Kind, M. Carrasco, Carretero, J., Castander, F. J., Cawthon, R., Chang, C., Chen, R., Choi, A., Conselice, C., Cordero, J., Crocce, M., da Costa, L. N., Pereira, M. E. da Silva, Dalal, R., Davis, C., de Jong, J. T. A., DeRose, J., Desai, S., Diehl, H. T., Dodelson, S., Doel, P., Doux, C., Drlica-Wagner, A., Dvornik, A., Eckert, K., Eifler, T. F., Elvin-Poole, J., Everett, S., Fang, X., Ferrero, I., Ferté, A., Flaugher, B., Friedrich, O., Frieman, J., García-Bellido, J., Gatti, M., Giannini, G., Giblin, B., Gruen, D., Gruendl, R. A., Gutierrez, G., Harrison, I., Hartley, W. G., Herner, K., Heymans, C., Hildebrandt, H., Hinton, S. R., Hoekstra, H., Hollowood, D. L., Honscheid, K., Huang, H., Huff, E. M., Huterer, D., James, D. J., Jarvis, M., Jeffrey, N., Jeltema, T., Joachimi, B., Joudaki, S., Kannawadi, A., Krause, E., Kuehn, K., Kuijken, K., Kuropatkin, N., Lahav, O., Leget, P. -F., Lemos, P., Li, S. -S., Li, X., Liddle, A. R., Lima, M., Lin, C. -A, Lin, H., MacCrann, N., Mahony, C., Marshall, J. L., McCullough, J., Mena-Fernández, J., Menanteau, F., Miquel, R., Mohr, J. J., Muir, J., Myles, J., Napolitano, N., Navarro-Alsina, A., Ogando, R. L. C., Palmese, A., Pandey, S., Park, Y., Paterno, M., Peacock, J. A., Petravick, D., Pieres, A., Malagón, A. A. Plazas, Porredon, A., Prat, J., Radovich, M., Raveri, M., Reischke, R., Robertson, N. C., Rollins, R. P., Romer, A. K., Roodman, A., Rykoff, E. S., Samuroff, S., Sánchez, C., Sanchez, E., Sanchez, J., Schneider, P., Secco, L. F., Sevilla-Noarbe, I., Shan, H. -Y., Sheldon, E., Shin, T., Sifón, C., Smith, M., Soares-Santos, M., Stölzner, B., Suchyta, E., Swanson, M. E. C., Tarle, G., Thomas, D., To, C., Troxel, M. A., Tröster, T., Tutusaus, I., Busch, J. L. van den, Varga, T. N., Walker, A. R., Weaverdyck, N., Wechsler, R. H., Weller, J., Wiseman, P., Wright, A. H., Yanny, B., Yin, B., Yoon, M., Zhang, Y., and Zuntz, J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present a joint cosmic shear analysis of the Dark Energy Survey (DES Y3) and the Kilo-Degree Survey (KiDS-1000) in a collaborative effort between the two survey teams. We find consistent cosmological parameter constraints between DES Y3 and KiDS-1000 which, when combined in a joint-survey analysis, constrain the parameter $S_8 = \sigma_8 \sqrt{\Omega_{\rm m}/0.3}$ with a mean value of $0.790^{+0.018}_{-0.014}$. The mean marginal is lower than the maximum a posteriori estimate, $S_8=0.801$, owing to skewness in the marginal distribution and projection effects in the multi-dimensional parameter space. Our results are consistent with $S_8$ constraints from observations of the cosmic microwave background by Planck, with agreement at the $1.7\sigma$ level. We use a Hybrid analysis pipeline, defined from a mock survey study quantifying the impact of the different analysis choices originally adopted by each survey team. We review intrinsic alignment models, baryon feedback mitigation strategies, priors, samplers and models of the non-linear matter power spectrum., Comment: 40 pages, 21 figures, 15 tables, accepted Open Journal of Astrophysics. Download the chains from https://des.ncsa.illinois.edu/releases/y3a2/Y3key-joint-des-kids or create your own chains with CosmoSIS using https://github.com/joezuntz/cosmosis-standard-library/blob/main/examples/des-y3_and_kids-1000.ini Watch the core team discuss this analysis at https://cosmologytalks.com/2023/05/26/des-kids

Published
2023
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227. Allowing Wigner's friend to sequentially measure incompatible observables

Author

Utreras-Alarcón, Aníbal, Cavalcanti, Eric G., and Wiseman, Howard M.

Subjects
Quantum Physics
Abstract

The Wigner's friend thought experiment has gained a resurgence of interest in recent years thanks to no-go theorems that extend it to Bell-like scenarios. One of these, by us and co-workers, showcased the contradiction that arises between quantum theory and a set of assumptions, weaker than those in Bell's theorem, which we named "local friendliness". Using these assumptions it is possible to arrive at a set of inequalities for a given scenario, and, in general, some of these inequalities will be harder to violate than the Bell inequalities for the same scenario. A crucial feature of the extended Wigner's friend scenario in our aforementioned work was the ability of a superobserver to reverse the unitary evolution that gives rise to their friend's measurement. Here, we present a new scenario where the superobserver can interact with the friend repeatedly in a single experimental instance, either by asking them directly for their result, thus ending that instance, or by reversing their measurement and instructing them to perform a new one. We show that, in these scenarios, the local friendliness inequalities will always be the same as Bell inequalities., Comment: 12 pages, 3 figures. No observers were harmed in the conduct of this work

Published
2023

228. Mapping quantum circuits to modular architectures with QUBO

Author

Bandic, Medina, Prielinger, Luise, Nüßlein, Jonas, Ovide, Anabel, Rodrigo, Santiago, Abadal, Sergi, van Someren, Hans, Vardoyan, Gayane, Alarcon, Eduard, Almudever, Carmen G., and Feld, Sebastian

Subjects
Quantum Physics, Computer Science - Emerging Technologies
Abstract

Modular quantum computing architectures are a promising alternative to monolithic QPU (Quantum Processing Unit) designs for scaling up quantum devices. They refer to a set of interconnected QPUs or cores consisting of tightly coupled quantum bits that can communicate via quantum-coherent and classical links. In multi-core architectures, it is crucial to minimize the amount of communication between cores when executing an algorithm. Therefore, mapping a quantum circuit onto a modular architecture involves finding an optimal assignment of logical qubits (qubits in the quantum circuit) to different cores with the aim to minimize the number of expensive inter-core operations while adhering to given hardware constraints. In this paper, we propose for the first time a Quadratic Unconstrained Binary Optimization (QUBO) technique to encode the problem and the solution for both qubit allocation and inter-core communication costs in binary decision variables. To this end, the quantum circuit is split into slices, and qubit assignment is formulated as a graph partitioning problem for each circuit slice. The costly inter-core communication is reduced by penalizing inter-core qubit communications. The final solution is obtained by minimizing the overall cost across all circuit slices. To evaluate the effectiveness of our approach, we conduct a detailed analysis using a representative set of benchmarks having a high number of qubits on two different multi-core architectures. Our method showed promising results and performed exceptionally well with very dense and highly-parallelized circuits that require on average 0.78 inter-core communications per two-qubit gate., Comment: Submitted to IEEE QCE 2023

Published
2023
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229. Complete nonsingular holomorphic foliations on Stein manifolds

Author

Alarcon, Antonio and Forstneric, Franc

Subjects
Mathematics - Complex Variables, Primary 32M17, 32M25, secondary 32H02, 37F75
Abstract

Let $X$ be a Stein manifold of complex dimension $n>1$ endowed with a Riemannian metric $\mathfrak{g}$. We show that for every integer $k$ with $\left[\frac{n}{2}\right] \le k \le n-1$ there is a nonsingular holomorphic foliation of dimension $k$ on $X$ all of whose leaves are topologically closed and $\mathfrak{g}$-complete. The same is true if $1\le k<\left[\frac{n}{2}\right]$ provided that there is a complex vector bundle epimorphism $TX\to X\times\mathbb{C}^{n-k}$. We also show that if $\mathcal{F}$ is a proper holomorphic foliation on $\mathbb{C}^n$ $(n>1)$ then for any Riemannian metric $\mathfrak{g}$ on $\mathbb{C}^n$ there is a holomorphic automorphism $\Phi$ of $\mathbb{C}^n$ such that the image foliation $\Phi_*\mathcal{F}$ is $\mathfrak{g}$-complete. The analogous result is obtained on every Stein manifold with Varolin's density property., Comment: Mediterranean J. Math., to appear. This version includes the final corrections

Published
2023
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230. A giant thin stellar stream in the Coma Galaxy Cluster

Author

Román, Javier, Rich, R. Michael, Ahvazi, Niusha, Sales, Laura, Li, Chester, Golini, Giulia, Trujillo, Ignacio, Knapen, Johan H., Peletier, Reynier F., and Sánchez-Alarcón, Pablo M.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The study of dynamically cold stellar streams reveals information about the gravitational potential where they reside and provides important constraints on dark matter properties. However, their intrinsic faintness makes detection beyond Local environments highly challenging. Here we report the detection of an extremely faint stellar stream ($\mu_{g,max}=$ 29.5 mag arcsec$^{-2}$) with an extraordinarily coherent and thin morphology in the Coma Galaxy Cluster. This Giant Coma Stream spans ~510 kpc in length and appears as a free-floating structure located at a projected distance of 0.8 Mpc from the centre of Coma. We do not identify any potential galaxy remnant or core, and the stream structure appears featureless in our data. We interpret the Giant Coma Stream as being a recently accreted, tidally disrupting passive dwarf. Using the Illustris-TNG50 simulation, we identify a case with similar characteristics, showing that, although rare, these types of streams are predicted to exist in $\Lambda$-CDM. Our work unveils the presence of free-floating, extremely faint and thin stellar streams in galaxy clusters, widening the environmental context for their promising future applications in the study of dark matter properties., Comment: Accepted for publication in A&A

Published
2023
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231. Efficient Robot Skill Learning with Imitation from a Single Video for Contact-Rich Fabric Manipulation

Author

Huo, Shengzeng, Duan, Anqing, Han, Lijun, Hu, Luyin, Wang, Hesheng, and Navarro-Alarcon, David

Subjects
Computer Science - Robotics
Abstract

Classical policy search algorithms for robotics typically require performing extensive explorations, which are time-consuming and expensive to implement with real physical platforms. To facilitate the efficient learning of robot manipulation skills, in this work, we propose a new approach comprised of three modules: (1) learning of general prior knowledge with random explorations in simulation, including state representations, dynamic models, and the constrained action space of the task; (2) extraction of a state alignment-based reward function from a single demonstration video; (3) real-time optimization of the imitation policy under systematic safety constraints with sampling-based model predictive control. This solution results in an efficient one-shot imitation-from-video strategy that simplifies the learning and execution of robot skills in real applications. Specifically, we learn priors in a scene of a task family and then deploy the policy in a novel scene immediately following a single demonstration, preventing time-consuming and risky explorations in the environment. As we do not make a strong assumption of dynamic consistency between the scenes, learning priors can be conducted in simulation to avoid collecting data in real-world circumstances. We evaluate the effectiveness of our approach in the context of contact-rich fabric manipulation, which is a common scenario in industrial and domestic tasks. Detailed numerical simulations and real-world hardware experiments reveal that our method can achieve rapid skill acquisition for challenging manipulation tasks., Comment: 12 pages, 12 figures

Published
2023

232. No two without three: Modelling dynamics of the trio RNA virus-defective interfering genomes-RNA satellite

Author

Lázaro, J. T., Albó, A., Alarcón, T., Elena, S. F., and Sardanyés, J.

Subjects
Mathematics - Dynamical Systems
Abstract

Almost all viruses, regardless of their genomic material, produce defective viral genomes (DVG) as an unavoidable byproduct of their error-prone replication. Defective interfering (DI) elements are a subgroup of DVGs that have been shown to interfere with the replication of the wild-type (WT) virus. Along with DIs, other genetic elements known as satellite RNAs (satRNAs), that show no genetic relatedness with the WT virus, can co-infect cells with WT helper viruses and take advantage of viral proteins for their own benefit. These satRNAs have effects that range from reduced symptom severity to enhanced virulence. The interference dynamics of DIs over WT viruses has been thoroughly modelled at within-cell, within-host, and population levels. However, nothing is known about the dynamics resulting from the nonlinear interactions between WT viruses and DIs in the presence of satellites, a process that is frequently seen in plant RNA viruses and in biomedically relevant pathosystems like hepatitis B virus and its $\delta$ satellite. Here, we look into a phenomenological mathematical model that describes how a WT virus replicates and produces DIs in presence of a satRNA at the intra-host level. The WT virus is subject to mechanisms of complementation, competition, and various levels of interference from DIs and the satRNA. Examining the dynamics analytically and numerically reveals three possible stable states: (i) full extinction, (ii) satellite extinction and virus-DIs coexistence and (iii) full coexistence. Assuming DIs replicate faster than the satRNA owed to their smaller size drives to scenario (ii), which implies that DIs could wipe out the satRNA. In addition, a small region of the parameter space exists wherein the system is bistable (either scenarios (ii) or (iii) are concurrently stable)., Comment: 22 pages, 9 figures

Published
2023

233. The James Webb Space Telescope Mission

Author

Gardner, Jonathan P., Mather, John C., Abbott, Randy, Abell, James S., Abernathy, Mark, Abney, Faith E., Abraham, John G., Abraham, Roberto, Abul-Huda, Yasin M., Acton, Scott, Adams, Cynthia K., Adams, Evan, Adler, David S., Adriaensen, Maarten, Aguilar, Jonathan Albert, Ahmed, Mansoor, Ahmed, Nasif S., Ahmed, Tanjira, Albat, Rüdeger, Albert, Loïc, Alberts, Stacey, Aldridge, David, Allen, Mary Marsha, Allen, Shaune S., Altenburg, Martin, Altunc, Serhat, Alvarez, Jose Lorenzo, Álvarez-Márquez, Javier, de Oliveira, Catarina Alves, Ambrose, Leslie L., Anandakrishnan, Satya M., Andersen, Gregory C., Anderson, Harry James, Anderson, Jay, Anderson, Kristen, Anderson, Sara M., Aprea, Julio, Archer, Benita J., Arenberg, Jonathan W., Argyriou, Ioannis, Arribas, Santiago, Artigau, Étienne, Arvai, Amanda Rose, Atcheson, Paul, Atkinson, Charles B., Averbukh, Jesse, Aymergen, Cagatay, Bacinski, John J., Baggett, Wayne E., Bagnasco, Giorgio, Baker, Lynn L., Balzano, Vicki Ann, Banks, Kimberly A., Baran, David A., Barker, Elizabeth A., Barrett, Larry K., Barringer, Bruce O., Barto, Allison, Bast, William, Baudoz, Pierre, Baum, Stefi, Beatty, Thomas G., Beaulieu, Mathilde, Bechtold, Kathryn, Beck, Tracy, Beddard, Megan M., Beichman, Charles, Bellagama, Larry, Bely, Pierre, Berger, Timothy W., Bergeron, Louis E., Darveau-Bernier, Antoine, Bertch, Maria D., Beskow, Charlotte, Betz, Laura E., Biagetti, Carl P., Birkmann, Stephan, Bjorklund, Kurt F., Blackwood, James D., Blazek, Ronald Paul, Blossfeld, Stephen, Bluth, Marcel, Boccaletti, Anthony, Boegner Jr., Martin E., Bohlin, Ralph C., Boia, John Joseph, Böker, Torsten, Bonaventura, N., Bond, Nicholas A., Bosley, Kari Ann, Boucarut, Rene A., Bouchet, Patrice, Bouwman, Jeroen, Bower, Gary, Bowers, Ariel S., Bowers, Charles W., Boyce, Leslye A., Boyer, Christine T., Boyer, Martha L., Boyer, Michael, Boyer, Robert, Bradley, Larry D., Brady, Gregory R., Brandl, Bernhard R., Brannen, Judith L., Breda, David, Bremmer, Harold G., Brennan, David, Bresnahan, Pamela A., Bright, Stacey N., Broiles, Brian J., Bromenschenkel, Asa, Brooks, Brian H., Brooks, Keira J., Brown, Bob, Brown, Bruce, Brown, Thomas M., Bruce, Barry W., Bryson, Jonathan G., Bujanda, Edwin D., Bullock, Blake M., Bunker, A. J., Bureo, Rafael, Burt, Irving J., Bush, James Aaron, Bushouse, Howard A., Bussman, Marie C., Cabaud, Olivier, Cale, Steven, Calhoon, Charles D., Calvani, Humberto, Canipe, Alicia M., Caputo, Francis M., Cara, Mihai, Carey, Larkin, Case, Michael Eli, Cesari, Thaddeus, Cetorelli, Lee D., Chance, Don R., Chandler, Lynn, Chaney, Dave, Chapman, George N., Charlot, S., Chayer, Pierre, Cheezum, Jeffrey I., Chen, Bin, Chen, Christine H., Cherinka, Brian, Chichester, Sarah C., Chilton, Zachary S., Chittiraibalan, Dharini, Clampin, Mark, Clark, Charles R., Clark, Kerry W., Clark, Stephanie M., Claybrooks, Edward E., Cleveland, Keith A., Cohen, Andrew L., Cohen, Lester M., Colón, Knicole D., Coleman, Benee L., Colina, Luis, Comber, Brian J., Comeau, Thomas M., Comer, Thomas, Reis, Alain Conde, Connolly, Dennis C., Conroy, Kyle E., Contos, Adam R., Contreras, James, Cook, Neil J., Cooper, James L., Cooper, Rachel Aviva, Correia, Michael F., Correnti, Matteo, Cossou, Christophe, Costanza, Brian F., Coulais, Alain, Cox, Colin R., Coyle, Ray T., Cracraft, Misty M., Noriega-Crespo, Alberto, Crew, Keith A., Curtis, Gary J., Cusveller, Bianca, Maciel, Cleyciane Da Costa, Dailey, Christopher T., Daugeron, Frédéric, Davidson, Greg S., Davies, James E., Davis, Katherine Anne, Davis, Michael S., Day, Ratna, de Chambure, Daniel, de Jong, Pauline, De Marchi, Guido, Dean, Bruce H., Decker, John E., Delisa, Amy S., Dell, Lawrence C., Dellagatta, Gail, Dembinska, Franciszka, Demosthenes, Sandor, Dencheva, Nadezhda M., Deneu, Philippe, DePriest, William W., Deschenes, Jeremy, Dethienne, Nathalie, Detre, Örs Hunor, Diaz, Rosa Izela, Dicken, Daniel, DiFelice, Audrey S., Dillman, Matthew, Disharoon, Maureen O., van Dishoeck, Ewine F., Dixon, William V., Doggett, Jesse B., Dominguez, Keisha L., Donaldson, Thomas S., Doria-Warner, Cristina M., Santos, Tony Dos, Doty, Heather, Douglas Jr., Robert E., Doyon, René, Dressler, Alan, Driggers, Jennifer, Driggers, Phillip A., Dunn, Jamie L., DuPrie, Kimberly C., Dupuis, Jean, Durning, John, Dutta, Sanghamitra B., Earl, Nicholas M., Eccleston, Paul, Ecobichon, Pascal, Egami, Eiichi, Ehrenwinkler, Ralf, Eisenhamer, Jonathan D., Eisenhower, Michael, Eisenstein, Daniel J., Hamel, Zaky El, Elie, Michelle L., Elliott, James, Elliott, Kyle Wesley, Engesser, Michael, Espinoza, Néstor, Etienne, Odessa, Etxaluze, Mireya, Evans, Leah, Fabreguettes, Luce, Falcolini, Massimo, Falini, Patrick R., Fatig, Curtis, Feeney, Matthew, Feinberg, Lee D., Fels, Raymond, Ferdous, Nazma, Ferguson, Henry C., Ferrarese, Laura, Ferreira, Marie-Héléne, Ferruit, Pierre, Ferry, Malcolm, Filippazzo, Joseph Charles, Firre, Daniel, Fix, Mees, Flagey, Nicolas, Flanagan, Kathryn A., Fleming, Scott W., Florian, Michael, Flynn, James R., Foiadelli, Luca, Fontaine, Mark R., Fontanella, Erin Marie, Forshay, Peter Randolph, Fortner, Elizabeth A., Fox, Ori D., Framarini, Alexandro P., Francisco, John I., Franck, Randy, Franx, Marijn, Franz, David E., Friedman, Scott D., Friend, Katheryn E., Frost, James R., Fu, Henry, Fullerton, Alexander W., Gaillard, Lionel, Galkin, Sergey, Gallagher, Ben, Galyer, Anthony D., Marín, Macarena García, Gardner, Lisa E., Garland, Dennis, Garrett, Bruce Albert, Gasman, Danny, Gáspár, András, Gastaud, René, Gaudreau, Daniel, Gauthier, Peter Timothy, Geers, Vincent, Geithner, Paul H., Gennaro, Mario, Gerber, John, Gereau, John C., Giampaoli, Robert, Giardino, Giovanna, Gibbons, Paul C., Gilbert, Karolina, Gilman, Larry, Girard, Julien H., Giuliano, Mark E., Gkountis, Konstantinos, Glasse, Alistair, Glassmire, Kirk Zachary, Glauser, Adrian Michael, Glazer, Stuart D., Goldberg, Joshua, Golimowski, David A., Gonzaga, Shireen P., Gordon, Karl D., Gordon, Shawn J., Goudfrooij, Paul, Gough, Michael J., Graham, Adrian J., Grau, Christopher M., Green, Joel David, Greene, Gretchen R., Greene, Thomas P., Greenfield, Perry E., Greenhouse, Matthew A., Greve, Thomas R., Greville, Edgar M., Grimaldi, Stefano, Groe, Frank E., Groebner, Andrew, Grumm, David M., Grundy, Timothy, Güdel, Manuel, Guillard, Pierre, Guldalian, John, Gunn, Christopher A., Gurule, Anthony, Gutman, Irvin Meyer, Guy, Paul D., Guyot, Benjamin, Hack, Warren J., Haderlein, Peter, Hagan, James B., Hagedorn, Andria, Hainline, Kevin, Haley, Craig, Hami, Maryam, Hamilton, Forrest Clifford, Hammann, Jeffrey, Hammel, Heidi B., Hanley, Christopher J., Hansen, Carl August, Hardy, Bruce, Harnisch, Bernd, Harr, Michael Hunter, Harris, Pamela, Hart, Jessica Ann, Hartig, George F., Hasan, Hashima, Hashim, Kathleen Marie, Hashimoto, Ryan, Haskins, Sujee J., Hawkins, Robert Edward, Hayden, Brian, Hayden, William L., Healy, Mike, Hecht, Karen, Heeg, Vince J., Hejal, Reem, Helm, Kristopher A., Hengemihle, Nicholas J., Henning, Thomas, Henry, Alaina, Henry, Ronald L., Henshaw, Katherine, Hernandez, Scarlin, Herrington, Donald C., Heske, Astrid, Hesman, Brigette Emily, Hickey, David L., Hilbert, Bryan N., Hines, Dean C., Hinz, Michael R., Hirsch, Michael, Hitcho, Robert S., Hodapp, Klaus, Hodge, Philip E., Hoffman, Melissa, Holfeltz, Sherie T., Holler, Bryan Jason, Hoppa, Jennifer Rose, Horner, Scott, Howard, Joseph M., Howard, Richard J., Huber, Jean M., Hunkeler, Joseph S., Hunter, Alexander, Hunter, David Gavin, Hurd, Spencer W., Hurst, Brendan J., Hutchings, John B., Hylan, Jason E., Ignat, Luminita Ilinca, Illingworth, Garth, Irish, Sandra M., Isaacs III, John C., Jackson Jr., Wallace C., Jaffe, Daniel T., Jahic, Jasmin, Jahromi, Amir, Jakobsen, Peter, James, Bryan, James, John C., James, LeAndrea Rae, Jamieson, William Brian, Jandra, Raymond D., Jayawardhana, Ray, Jedrzejewski, Robert, Jeffers, Basil S., Jensen, Peter, Joanne, Egges, Johns, Alan T., Johnson, Carl A., Johnson, Eric L., Johnson, Patricia, Johnson, Phillip Stephen, Johnson, Thomas K., Johnson, Timothy W., Johnstone, Doug, Jollet, Delphine, Jones, Danny P., Jones, Gregory S., Jones, Olivia C., Jones, Ronald A., Jones, Vicki, Jordan, Ian J., Jordan, Margaret E., Jue, Reginald, Jurkowski, Mark H., Justis, Grant, Justtanont, Kay, Kaleida, Catherine C., Kalirai, Jason S., Kalmanson, Phillip Cabrales, Kaltenegger, Lisa, Kammerer, Jens, Kan, Samuel K., Kanarek, Graham Childs, Kao, Shaw-Hong, Karakla, Diane M., Karl, Hermann, Kassin, Susan A., Kauffman, David D., Kavanagh, Patrick, Kelley, Leigh L., Kelly, Douglas M., Kendrew, Sarah, Kennedy, Herbert V., Kenny, Deborah A., Keski-Kuha, Ritva A., Keyes, Charles D., Khan, Ali, Kidwell, Richard C., Kimble, Randy A., King, James S., King, Richard C., Kinzel, Wayne M., Kirk, Jeffrey R., Kirkpatrick, Marc E., Klaassen, Pamela, Klingemann, Lana, Klintworth, Paul U., Knapp, Bryan Adam, Knight, Scott, Knollenberg, Perry J., Knutsen, Daniel Mark, Koehler, Robert, Koekemoer, Anton M., Kofler, Earl T., Kontson, Vicki L., Kovacs, Aiden Rose, Kozhurina-Platais, Vera, Krause, Oliver, Kriss, Gerard A., Krist, John, Kristoffersen, Monica R., Krogel, Claudia, Krueger, Anthony P., Kulp, Bernard A., Kumari, Nimisha, Kwan, Sandy W., Kyprianou, Mark, Labador, Aurora Gadiano, Labiano, Álvaro, Lafrenière, David, Lagage, Pierre-Olivier, Laidler, Victoria G., Laine, Benoit, Laird, Simon, Lajoie, Charles-Philippe, Lallo, Matthew D., Lam, May Yen, LaMassa, Stephanie Marie, Lambros, Scott D., Lampenfield, Richard Joseph, Lander, Matthew Ed, Langston, James Hutton, Larson, Kirsten, Larson, Melora, LaVerghetta, Robert Joseph, Law, David R., Lawrence, Jon F., Lee, David W., Lee, Janice, Lee, Yat-Ning Paul, Leisenring, Jarron, Leveille, Michael Dunlap, Levenson, Nancy A., Levi, Joshua S., Levine, Marie B., Lewis, Dan, Lewis, Jake, Lewis, Nikole, Libralato, Mattia, Lidon, Norbert, Liebrecht, Paula Louisa, Lightsey, Paul, Lilly, Simon, Lim, Frederick C., Lim, Pey Lian, Ling, Sai-Kwong, Link, Lisa J., Link, Miranda Nicole, Lipinski, Jamie L., Liu, XiaoLi, Lo, Amy S., Lobmeyer, Lynette, Logue, Ryan M., Long, Chris A., Long, Douglas R., Long, Ilana D., Long, Knox S., López-Caniego, Marcos, Lotz, Jennifer M., Love-Pruitt, Jennifer M., Lubskiy, Michael, Luers, Edward B., Luetgens, Robert A., Luevano, Annetta J., Lui, Sarah Marie G. Flores, Lund III, James M., Lundquist, Ray A., Lunine, Jonathan, Lützgendorf, Nora, Lynch, Richard J., MacDonald, Alex J., MacDonald, Kenneth, Macias, Matthew J., Macklis, Keith I., Maghami, Peiman, Maharaja, Rishabh Y., Maiolino, Roberto, Makrygiannis, Konstantinos G., Malla, Sunita Giri, Malumuth, Eliot M., Manjavacas, Elena, Marini, Andrea, Marrione, Amanda, Marston, Anthony, Martel, André R, Martin, Didier, Martin, Peter G., Martinez, Kristin L., Maschmann, Marc, Masci, Gregory L., Masetti, Margaret E., Maszkiewicz, Michael, Matthews, Gary, Matuskey, Jacob E., McBrayer, Glen A., McCarthy, Donald W., McCaughrean, Mark J., McClare, Leslie A., McClare, Michael D., McCloskey, John C., McClurg, Taylore D., McCoy, Martin, McElwain, Michael W., McGregor, Roy D., McGuffey, Douglas B., McKay, Andrew G., McKenzie, William K., McLean, Brian, McMaster, Matthew, McNeil, Warren, De Meester, Wim, Mehalick, Kimberly L., Meixner, Margaret, Meléndez, Marcio, Menzel, Michael P., Menzel, Michael T., Merz, Matthew, Mesterharm, David D., Meyer, Michael R., Meyett, Michele L., Meza, Luis E., Midwinter, Calvin, Milam, Stefanie N., Miller, Jay Todd, Miller, William C., Miskey, Cherie L., Misselt, Karl, Mitchell, Eileen P., Mohan, Martin, Montoya, Emily E., Moran, Michael J., Morishita, Takahiro, Moro-Martín, Amaya, Morrison, Debra L., Morrison, Jane, Morse, Ernie C., Moschos, Michael, Moseley, S. H., Mosier, Gary E., Mosner, Peter, Mountain, Matt, Muckenthaler, Jason S., Mueller, Donald G., Mueller, Migo, Muhiem, Daniella, Mühlmann, Prisca, Mullally, Susan Elizabeth, Mullen, Stephanie M., Munger, Alan J, Murphy, Jess, Murray, Katherine T., Muzerolle, James C., Mycroft, Matthew, Myers, Andrew, Myers, Carey R., Myers, Fred Richard R., Myers, Richard, Myrick, Kaila, Nagle IV, Adrian F., Nayak, Omnarayani, Naylor, Bret, Neff, Susan G., Nelan, Edmund P., Nella, John, Nguyen, Duy Tuong, Nguyen, Michael N., Nickson, Bryony, Nidhiry, John Joseph, Niedner, Malcolm B., Nieto-Santisteban, Maria, Nikolov, Nikolay K., Nishisaka, Mary Ann, Nota, Antonella, O'Mara, Robyn C., Oboryshko, Michael, O'Brien, Marcus B., Ochs, William R., Offenberg, Joel D., Ogle, Patrick Michael, Ohl, Raymond G., Olmsted, Joseph Hamden, Osborne, Shannon Barbara, O'Shaughnessy, Brian Patrick, Östlin, Göran, O'Sullivan, Brian, Otor, O. Justin, Ottens, Richard, Ouellette, Nathalie N. -Q., Outlaw, Daria J., Owens, Beverly A., Pacifici, Camilla, Page, James Christophe, Paranilam, James G., Park, Sang, Parrish, Keith A., Paschal, Laura, Patapis, Polychronis, Patel, Jignasha, Patrick, Keith, Pattishall Jr., Robert A., Paul, Douglas William, Paul, Shirley J., Pauly, Tyler Andrew, Pavlovsky, Cheryl M., Peña-Guerrero, Maria, Pedder, Andrew H., Peek, Matthew Weldon, Pelham, Patricia A., Penanen, Konstantin, Perriello, Beth A., Perrin, Marshall D., Perrine, Richard F., Perrygo, Chuck, Peslier, Muriel, Petach, Michael, Peterson, Karla A., Pfarr, Tom, Pierson, James M., Pietraszkiewicz, Martin, Pilchen, Guy, Pipher, Judy L., Pirzkal, Norbert, Pitman, Joseph T., Player, Danielle M., Plesha, Rachel, Plitzke, Anja, Pohner, John A., Poletis, Karyn Konstantin, Pollizzi, Joseph A., Polster, Ethan, Pontius, James T., Pontoppidan, Klaus, Porges, Susana C., Potter, Gregg D., Prescott, Stephen, Proffitt, Charles R., Pueyo, Laurent, Neira, Irma Aracely Quispe, Radich, Armando, Rager, Reiko T., Rameau, Julien, Ramey, Deborah D., Alarcon, Rafael Ramos, Rampini, Riccardo, Rapp, Robert, Rashford, Robert A., Rauscher, Bernard J., Ravindranath, Swara, Rawle, Timothy, Rawlings, Tynika N., Ray, Tom, Regan, Michael W., Rehm, Brian, Rehm, Kenneth D., Reid, Neill, Reis, Carl A., Renk, Florian, Reoch, Tom B., Ressler, Michael, Rest, Armin W., Reynolds, Paul J., Richon, Joel G., Richon, Karen V., Ridgaway, Michael, Riedel, Adric Richard, Rieke, George H., Rieke, Marcia, Rifelli, Richard E., Rigby, Jane R., Riggs, Catherine S., Ringel, Nancy J., Ritchie, Christine E., Rix, Hans-Walter, Robberto, Massimo, Robinson, Michael S., Robinson, Orion, Rock, Frank W., Rodriguez, David R., del Pino, Bruno Rodríguez, Roellig, Thomas, Rohrbach, Scott O., Roman, Anthony J., Romelfanger, Frederick J., Romo Jr., Felipe P., Rosales, Jose J., Rose, Perry, Roteliuk, Anthony F., Roth, Marc N., Rothwell, Braden Quinn, Rouzaud, Sylvain, Rowe, Jason, Rowlands, Neil, Roy, Arpita, Royer, Pierre, Rui, Chunlei, Rumler, Peter, Rumpl, William, Russ, Melissa L., Ryan, Michael B., Ryan, Richard M., Saad, Karl, Sabata, Modhumita, Sabatino, Rick, Sabbi, Elena, Sabelhaus, Phillip A., Sabia, Stephen, Sahu, Kailash C., Saif, Babak N., Salvignol, Jean-Christophe, Samara-Ratna, Piyal, Samuelson, Bridget S., Sanders, Felicia A., Sappington, Bradley, Sargent, B. A., Sauer, Arne, Savadkin, Bruce J., Sawicki, Marcin, Schappell, Tina M., Scheffer, Caroline, Scheithauer, Silvia, Scherer, Ron, Schiff, Conrad, Schlawin, Everett, Schmeitzky, Olivier, Schmitz, Tyler S., Schmude, Donald J., Schneider, Analyn, Schreiber, Jürgen, Schroeven-Deceuninck, Hilde, Schultz, John J., Schwab, Ryan, Schwartz, Curtis H., Scoccimarro, Dario, Scott, John F., Scott, Michelle B., Seaton, Bonita L., Seely, Bruce S., Seery, Bernard, Seidleck, Mark, Sembach, Kenneth, Shanahan, Clare Elizabeth, Shaughnessy, Bryan, Shaw, Richard A., Shay, Christopher Michael, Sheehan, Even, Sheth, Kartik, Shih, Hsin-Yi, Shivaei, Irene, Siegel, Noah, Sienkiewicz, Matthew G., Simmons, Debra D., Simon, Bernard P., Sirianni, Marco, Sivaramakrishnan, Anand, Slade, Jeffrey E., Sloan, G. C., Slocum, Christine E., Slowinski, Steven E., Smith, Corbett T., Smith, Eric P., Smith, Erin C., Smith, Koby, Smith, Robert, Smith, Stephanie J., Smolik, John L., Soderblom, David R., Sohn, Sangmo Tony, Sokol, Jeff, Sonneborn, George, Sontag, Christopher D., Sooy, Peter R., Soummer, Remi, Southwood, Dana M., Spain, Kay, Sparmo, Joseph, Speer, David T., Spencer, Richard, Sprofera, Joseph D., Stallcup, Scott S., Stanley, Marcia K., Stansberry, John A., Stark, Christopher C., Starr, Carl W., Stassi, Diane Y., Steck, Jane A., Steeley, Christine D., Stephens, Matthew A., Stephenson, Ralph J., Stewart, Alphonso C., Stiavelli, Massimo, Stockman Jr., Hervey, Strada, Paolo, Straughn, Amber N., Streetman, Scott, Strickland, David Kendal, Strobele, Jingping F., Stuhlinger, Martin, Stys, Jeffrey Edward, Such, Miguel, Sukhatme, Kalyani, Sullivan, Joseph F., Sullivan, Pamela C., Sumner, Sandra M., Sun, Fengwu, Sunnquist, Benjamin Dale, Swade, Daryl Allen, Swam, Michael S., Swenton, Diane F., Swoish, Robby A., Litten, Oi In Tam, Tamas, Laszlo, Tao, Andrew, Taylor, David K., Taylor, Joanna M., Plate, Maurice te, Van Tea, Mason, Teague, Kelly K., Telfer, Randal C., Temim, Tea, Texter, Scott C., Thatte, Deepashri G., Thompson, Christopher Lee, Thompson, Linda M., Thomson, Shaun R., Thronson, Harley, Tierney, C. M., Tikkanen, Tuomo, Tinnin, Lee, Tippet, William Thomas, Todd, Connor William, Tran, Hien D., Trauger, John, Trejo, Edwin Gregorio, Truong, Justin Hoang Vinh, Tsukamoto, Christine L., Tufail, Yasir, Tumlinson, Jason, Tustain, Samuel, Tyra, Harrison, Ubeda, Leonardo, Underwood, Kelli, Uzzo, Michael A., Vaclavik, Steven, Valenduc, Frida, Valenti, Jeff A., Van Campen, Julie, van de Wetering, Inge, Van Der Marel, Roeland P., van Haarlem, Remy, Vandenbussche, Bart, Vanterpool, Dona D., Vernoy, Michael R., Costas, Maria Begoña Vila, Volk, Kevin, Voorzaat, Piet, Voyton, Mark F., Vydra, Ekaterina, Waddy, Darryl J., Waelkens, Christoffel, Wahlgren, Glenn Michael, Walker Jr., Frederick E., Wander, Michel, Warfield, Christine K., Warner, Gerald, Wasiak, Francis C., Wasiak, Matthew F., Wehner, James, Weiler, Kevin R., Weilert, Mark, Weiss, Stanley B., Wells, Martyn, Welty, Alan D., Wheate, Lauren, Wheeler, Thomas P., White, Christy L., Whitehouse, Paul, Whiteleather, Jennifer Margaret, Whitman, William Russell, Williams, Christina C., Willmer, Christopher N. A., Willott, Chris J., Willoughby, Scott P., Wilson, Andrew, Wilson, Debra, Wilson, Donna V., Windhorst, Rogier, Wislowski, Emily Christine, Wolfe, David J., Wolfe, Michael A., Wolff, Schuyler, Wondel, Amancio, Woo, Cindy, Woods, Robert T., Worden, Elaine, Workman, William, Wright, Gillian S., Wu, Carl, Wu, Chi-Rai, Wun, Dakin D., Wymer, Kristen B., Yadetie, Thomas, Yan, Isabelle C., Yang, Keith C., Yates, Kayla L., Yeager, Christopher R., Yerger, Ethan John, Young, Erick T., Young, Gary, Yu, Gene, Yu, Susan, Zak, Dean S., Zeidler, Peter, Zepp, Robert, Zhou, Julia, Zincke, Christian A., Zonak, Stephanie, and Zondag, Elisabeth

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit., Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figures

Published
2023
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234. Molecules with ALMA at Planet-forming Scales (MAPS). Complex Kinematics in the AS 209 Disk Induced by a Forming Planet and Disk Winds

Author

Galloway-Sprietsma, Maria, Bae, Jaehan, Teague, Richard, Benisty, Myriam, Facchini, Stefano, Aikawa, Yuri, Alarcón, Felipe, Andrews, Sean M., Bergin, Edwin, Cataldi, Gianni, Cleeves, L. Ilsedore, Czekala, Ian, Guzmán, Viviana V., Huang, Jane, Law, Charles J., Gal, Romane Le, Liu, Yao, Long, Feng, Ménard, François, Öberg, Karin I., Walsh, Catherine, and Wilner, David J.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

We study the kinematics of the AS 209 disk using the J=2-1 transitions of $^{12}$CO, $^{13}$CO, and C$^{18}$O. We derive the radial, azimuthal, and vertical velocity of the gas, taking into account the lowered emission surface near the annular gap at ~1.7 (200 au) within which a candidate circumplanetary disk-hosting planet has been reported previously. In $^{12}$CO and $^{13}$CO, we find a coherent upward flow arising from the gap. The upward gas flow is as fast as $150~{\rm m~s}^{-1}$ in the regions traced by $^{12}$CO emission, which corresponds to about 50% of the local sound speed or $6\%$ of the local Keplerian speed. Such an upward gas flow is difficult to reconcile with an embedded planet alone. Instead, we propose that magnetically driven winds via ambipolar diffusion are triggered by the low gas density within the planet-carved gap, dominating the kinematics of the gap region. We estimate the ambipolar Elsasser number, Am, using the HCO$^+$ column density as a proxy for ion density and find that Am is ~0.1 at the radial location of the upward flow. This value is broadly consistent with the value at which numerical simulations find ambipolar diffusion drives strong winds. We hypothesize the activation of magnetically-driven winds in a planet-carved gap can control the growth of the embedded planet. We provide a scaling relationship which describes the wind-regulated terminal mass: adopting parameters relevant to 100 au from a solar-mass star, we find the wind-regulated terminal mass is about one Jupiter mass, which may help explain the dearth of directly imaged super-Jovian-mass planets., Comment: This paper has been accepted for publication in the Astrophysical Journal (ApJ)

Published
2023
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235. Mapping quantum algorithms to multi-core quantum computing architectures

Author

Ovide, Anabel, Rodrigo, Santiago, Bandic, Medina, Van Someren, Hans, Feld, Sebastian, Abadal, Sergi, Alarcon, Eduard, and Almudever, Carmen G.

Subjects
Quantum Physics, Computer Science - Emerging Technologies
Abstract

Current monolithic quantum computer architectures have limited scalability. One promising approach for scaling them up is to use a modular or multi-core architecture, in which different quantum processors (cores) are connected via quantum and classical links. This new architectural design poses new challenges such as the expensive inter-core communication. To reduce these movements when executing a quantum algorithm, an efficient mapping technique is required. In this paper, a detailed critical discussion of the quantum circuit mapping problem for multi-core quantum computing architectures is provided. In addition, we further explore the performance of a mapping method, which is formulated as a partitioning over time graph problem, by performing an architectural scalability analysis.

Published
2023

236. Oka-1 manifolds

Author

Alarcon, Antonio and Forstneric, Franc

Subjects
Mathematics - Complex Variables, Primary 32E30, 32H02, 32Q56, secondary 14H55
Abstract

We introduce and study a new class of complex manifolds, Oka-1 manifolds, characterized by the property that holomorphic maps from any open Riemann surface to the manifold satisfy the Runge approximation and the Weierstrass interpolation conditions. We prove that every complex manifold which is dominable at most points by spanning tubes of complex lines in affine spaces is an Oka-1 manifold. In particular, a manifold dominable by $\mathbb C^n$ at most points is an Oka-1 manifold. We provide many examples of Oka-1 manifolds among compact complex surfaces, including all Kummer surfaces and all elliptic K3 surfaces. The class of Oka-1 manifolds is invariant under Oka maps inducing a surjective homomorphism of fundamental groups; this includes holomorphic fibre bundles with connected Oka fibres. In another direction, we prove that every bordered Riemann surface admits a holomorphic map with dense image in any connected complex manifold. The analogous result holds for holomorphic Legendrian immersions in an arbitrary connected complex contact manifold., Comment: Theorem 9.1 has been downgraded to the status of a conjecture since we were unable to verify the correctness of a preexisting result which is used in the proof

Published
2023

237. Scalable multi-chip quantum architectures enabled by cryogenic hybrid wireless/quantum-coherent network-in-package

Author

Alarcón, Eduard, Abadal, Sergi, Sebastiano, Fabio, Babaie, Masoud, Charbon, Edoardo, Bolívar, Peter Haring, Palesi, Maurizio, Blokhina, Elena, Leipold, Dirk, Staszewski, Bogdan, Garcia-Sáez, Artur, and Almudever, Carmen G.

Subjects
Quantum Physics, Computer Science - Emerging Technologies
Abstract

The grand challenge of scaling up quantum computers requires a full-stack architectural standpoint. In this position paper, we will present the vision of a new generation of scalable quantum computing architectures featuring distributed quantum cores (Qcores) interconnected via quantum-coherent qubit state transfer links and orchestrated via an integrated wireless interconnect., Comment: 5 pages, 2 figures, accepted for presentation at the IEEE International Symposium on Circuits and Systems (ISCAS) 2023

Published
2023

238. Dynamic generation of photonic spatial quantum states with an all-fiber platform

Author

Alarcón, A., Argillander, J., Spegel-Lexne, D., and Xavier, G. B.

Subjects
Quantum Physics
Abstract

Photonic spatial quantum states are a subject of great interest for applications in quantum communication. One important challenge has been how to dynamically generate these states using only fiber-optical components. Here we propose and experimentally demonstrate an all-fiber system that can dynamically switch between any general transverse spatial qubit state based on linearly polarized modes. Our platform is based on a fast optical switch based on a Sagnac interferometer combined with a photonic lantern and few-mode optical fibers. We show switching times between spatial modes on the order of 5 ns and demonstrate the applicability of our scheme for quantum technologies by demonstrating a measurement-device-independent (MDI) quantum random number generator based on our platform. We run the generator continuously over 15 hours, acquiring over 13.46 Gbits of random numbers, of which we ensure that at least 60.52% are private, following the MDI protocol. Our results show the use of photonic lanterns to dynamically create spatial modes using only fiber components, which due to their robustness and integration capabilities, have important consequences for photonic classical and quantum information processing., Comment: 11 pages, 4 figures

Published
2023
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239. Toward Standardized Performance Evaluation of Flow-guided Nanoscale Localization

Author

López, Arnau Brosa, Lemic, Filip, Struye, Jakob, Gómez, Jorge Torres, Municio, Esteban, Delgado, Carmen, Bartra, Gerard Calvo, Dressler, Falko, Alarcón, Eduard, Famaey, Jeroen, Abadal, Sergi, and Pérez, Xavier Costa

Subjects
Computer Science - Networking and Internet Architecture, Computer Science - Emerging Technologies, Electrical Engineering and Systems Science - Systems and Control
Abstract

Nanoscale devices with Terahertz (THz) communication capabilities are envisioned to be deployed within human bloodstreams. Such devices will enable fine-grained sensing-based applications for detecting early indications (i.e., biomarkers) of various health conditions, as well as actuation-based ones such as targeted drug delivery. Associating the locations of such events with the events themselves would provide an additional utility for precision diagnostics and treatment. This vision yielded a new class of in-body localization coined under the term "flow-guided nanoscale localization". Such localization can be piggybacked on THz communication for detecting body regions in which biological events were observed based on the duration of one circulation of a nanodevice in the bloodstream. From a decades-long research on objective benchmarking of "traditional" indoor localization, as well as its eventual standardization (e.g., ISO/IEC 18305:2016), we know that in early stages the reported performance results were often incomplete (e.g., targeting a subset of relevant performance metrics), carrying out benchmarking experiments in different evaluation environments and scenarios, and utilizing inconsistent performance indicators. To avoid such a "lock-in" in flow-guided localization, in this paper we propose a workflow for standardized performance evaluation of such localization. The workflow is implemented in the form of an open-source simulation framework that is able to jointly account for the mobility of the nanodevices, in-body THz communication between with on-body anchors, and energy-related and other technological constraints (e.g., pulse-based modulation) at the nanodevice level. Accounting for these constraints, the framework is able to generate the raw data that can be streamlined into different flow-guided localization solutions for generating standardized performance benchmarks., Comment: 10 pages, 9 figures, 34 references, code available at: https://bitbucket.org/filip_lemic/flow-guided-localization-in-ns3/src/sequential/

Published
2023

240. Observations of two super fast rotator NEAs: 2021 NY$_1$ and 2022 AB

Author

Licandro, J., Popescu, M., Tatsumi, E., Alarcon, M. R., Serra-Ricart, M., Medeiros, H., Morate, D., and de Leon, J.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

In the framework of the Visible NEAs Observations Survey (ViNOS) that uses several telescopes at the Canary Islands observatories since 2018, we observed two super fast rotator NEAs, 2021 NY$_1$ and 2022 AB. We obtained photometry and spectrophotometry of both targets and visible spectroscopy of 2022 AB. Light curves of 2021 NY$_1$ obtained in 4 different nights between Sept. 30 and Oct. 16, 2021 return a rotation period $P=13.3449\pm0.0013$ minutes and a light curve amplitude $A = 1.00$ mag. We found that 2021 NY$_1$ is a very elongated super fast rotator with an axis ratio $a/b \ge 3.6$. We also report colours $(g-r) = 0.664 \pm 0.013$, $(r-i) = 0.186 \pm 0.013$, and $(i-z_s) = -0.117 \pm 0.012$ mag. These are compatible with an S-type asteroid. The light curves of 2022 AB obtained on Jan. 5 and Jan. 8, 2021 show a rotation period $P=3.0304\pm0.0008$ minutes, with amplitudes $A = 0.52$ and $A =0.54$ mag. 2022 AB is also an elongated object with axis ratio $a/b \ge 1.6$. The obtained colours are $(g-r) = 0.400 \pm 0.017$, $(r-i) = 0.133 \pm 0.017$, and $(i-z_s) = 0.093 \pm 0.016$. These colours are similar to those of the X-types, but with an unusually high $(g-r)$ value. Spectra obtained on Jan. 12 and Jan. 14, 2022, are consistent with the reported colours. The spectral upturn over the 0.4 - 0.6 $\mu m $ region of 2022 AB does not fit with any known asteroid taxonomical class or meteorite spectrum, confirming its unusual surface properties., Comment: 9 pages, 7 figures

Published
2023
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241. Benefits of omega-3 fatty acid dietary supplementation on health-related quality of life in patients with meibomian gland dysfunction

Author

Oleñik A, Mahillo-Fernández I, Alejandre-Alba N, Fernández-Sanz G, Alarcón Pérez M, Luxan S, Quintana S, Martínez de Carneros Llorente A, García-Sandoval B, and Jiménez-Alfaro I

Subjects
Ophthalmology, RE1-994
Abstract

Andrea Oleñik, Ignacio Mahillo-Fernández, Nicolás Alejandre-Alba, Guillermo Fernández-Sanz, María Alarcón Pérez, Sol Luxan, Silvia Quintana, Alfonso Martínez de Carneros Llorente, Blanca García-Sandoval, Ignacio Jiménez-AlfaroDepartment of Ophthalmology, Fundación Jiménez Díaz, Madrid, SpainBackground: We assessed the impact of a dietary supplement based on the combination of omega-3 essential fatty acids and antioxidants on health-related quality of life in patients with meibomian gland dysfunction (MGD).Methods: Patients of either sex (aged 18–85 years) diagnosed with MGD according to criteria identified at a 2011 International Workshop on Meibomian Gland Dysfunction participated in this randomized, double-masked, placebo-controlled study. Group A patients (controls) received an oral placebo supplement and group B patients received the oral study supplement (Brudysec® 1.5 g; Brudy Laboratories, Barcelona, Spain). At baseline and at 3-month follow-up, the patients completed the 36-Item Short Form Health Survey questionnaire using a Spanish validated version. The Physical (PCS) and Mental (MCS) Component Summary scores were the main outcome variables.Results: A total of 61 patients completed the study (group A, n=31; group B, n=30). There were no significant differences in PCS and MCS scores at baseline between the two study groups, but after 3 months of treatment, significantly higher mean PCS and MSC scores were observed in patients treated with the active omega-3 dietary supplement as compared with controls (mean [standard deviation] PCS score 53.33±5.57 versus 47.46±7.31, P=0.008; mean MCS score 54.60±5.64 versus 47.80±8.45, P=0.0005). Moreover, mean differences between values at 3 months as compared with baseline were statistically significant for patients in group B (PCS score 7.14±5.81, 95% confidence interval 4.97–9.31, P=0.000; MCS score 5.96±7.64, 95% confidence interval 3.10–8.81, P=0.0002), whereas mean differences in patients assigned to group A were not statistically significant.Conclusion: Dietary supplementation with a combination of omega-3 essential fatty acids and antioxidants had a significant beneficial effect on HRQoL (health-related quality of life) in patients with MGD.Keywords: antioxidants, Brudysec®, nutraceuticals, polyunsaturated fatty acids

Published
2014

242. Cytokines profile in gingival crevicular fluid of subjects wearing fixed dental prostheses: a systematic review and meta-analysis

Author

Mario Alberto Alarcón-Sánchez and Artak Heboyan

Subjects
Dental fixed prostheses, Metal–ceramic, Ceramic free-metal, Cytokines, Systematic review, Medicine
Abstract

Abstract Background Fixed dental prostheses (FDP) can affect the production of inflammatory cytokines causing damage to periodontal tissues. A systematic review and meta-analysis was carried out with the following two objectives: (1) to determine the prevalence and function of the different inflammatory cytokines present in gingival crevicular fluid (GCF) of teeth with metal–ceramic (M/C) and all-ceramic (A-Cs) prostheses, and (2) to analyze and compare the levels of inflammatory cytokines in GCF of teeth with M/C and A-Cs prostheses. Methods The protocol followed PRISMA and Cochrane guidelines and was registered in the OSF:10.17605/OSF.IO/RBHJU. A digital search was conducted in the databases PubMed/MEDLINE, Cochrane Library, Dentistry & Oral Sciences Source, Scopus, Web of Science, ScienceDirect, and Google Scholar, from July 15th, 2000 to March 1st, 2024. Study quality was assessed using the JBI tool for cross-sectional and longitudinal studies. A meta-analysis was performed using a random-effects model to evaluate the concentration of IL-1β in GCF of teeth with FDP of M/C and A-Cs. Results The search strategy provided a total of 8,172 articles, of which 14 investigations met the inclusion criteria. The total number of patients studied was 468 of whom 53% were women and the rest (47%) were men. The ages of the patients ranged from 19 to 73 years, with a mean age ± standard deviation (SD) of 38,5 ± 12,8 years. A total of 843 fixed dental prostheses were studied, of which 407 (48,27%) were M/C prostheses and 410 (48,63%) were A-Cs prostheses. We found that the levels of IL-1β, IL-1α, PGE2, NKA, CGRP, and CX3CL1 were increased in teeth with M/C prostheses compared to teeth with A-Cs prostheses. Meta-analysis revealed that there are no significant differences between IL-1β levels in GCF in teeth with M/C prostheses compared to teeth with A-Cs prostheses (SMD = 13.89 pg/ml (CI = −14.29–42.08), p = > 0.05). Conclusions A trend toward increased levels of inflammatory cytokines was found in GCF of teeth with M/C prostheses compared to teeth with A-Cs prostheses.

Published
2024
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243. Expression of IL-33 in subjects with periodontitis: a systematic review and meta-analysis

Author

Mario Alberto Alarcón-Sánchez, Norma Samanta Romero-Castro, Salvador Reyes-Fernández, Edgar Uriel Sánchez-Tecolapa, and Artak Heboyan

Subjects
Interleukin-33, Chronic periodontitis, Serum, Plasma, Saliva, Biomarkers, Medicine
Abstract

Abstract Background Activation of the IL-33/ST2 axis leads to the production of proinflammatory cytokines and thus to the triggering of osteoclastogenesis, which is why it plays an important role in the immunopathogenesis of periodontitis. The aim of this study was to compare IL-33 levels in serum, plasma, saliva and gingival crevicular fluid (GCF) of subjects with chronic periodontitis (CP) in comparison with the control group (CG). Methods This systematic review and meta-analysis followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) and was registered in the Open Science Framework (OSF): https://doi.org/10.17605/OSF.IO/YHUWA . Six electronic databases were used for study identification; PubMed, Google Scholar, ScienceDirect, Web of Science, Scopus and Dentistry & Oral Sciences Source from March 10, 2012 to April 30, 2024. The Joanna Briggs Institute (JBI) tool was used to assess the quality of the included cross-sectional articles and clinical trials. Results Of the 949 articles identified, 14 were included according to the inclusion and exclusion criteria. The total number of individuals studied in the included investigations was 814 of whom 445 had CP and 369 were healthy. The reported age range was from 20 to 50 years, with a mean age ± standard deviation of 40.29 ± 7.83 years. Four hundred and twenty-six (52%) patients were men and 388 (48%) were women. Meta-analysis revealed that there is an increase in IL-33 levels in plasma, saliva and GCF of subjects with CP compared to CG (p = *

Published
2024
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244. Podoplanin immunoexpression in odontogenic lesions: a systematic review, meta-analysis, and integrated bioinformatic analysis

Author

Mario Alberto Alarcón-Sánchez, Getsemani Luna-Bonilla, Selenne Romero-Servin, and Artak Heboyan

Subjects
PDPN Protein, Human, Odontogenic Tumors, Odontogenic Cysts, Systematic Review, Pathology, RB1-214
Abstract

Abstract Background Podoplanin (PDPN) is a transmembrane glycoprotein implicated in the pathogenesis of odontogenic lesions (OL). It is localized at the membrane and cytoplasmic level, and its interaction with other proteins could trigger cell proliferation, invasion and migration. The main objective of this systematic review is to explore the immunoexpression pattern of podoplanin in OL. In addition, as secondary objectives, we aimed to compare the immunostaining intensity of PDPN in OL, to analyze its interaction networks by bioinformatic analysis and to highlight its importance as a potential diagnostic marker useful in the pathogenesis of OL. Methods The protocol was developed following PRISMA and Cochrane guidelines. The digital search was performed in the databases: PubMed/MEDLINE, ScienceDirect, Scopus, Web of Science and Google Schoolar from August 15, 2010 to June 15, 2023. We included cross-sectional and cohort studies that will analyze the pattern of PDPN immunoexpression in OL. Two investigators independently searched for eligible articles, selected titles and abstracts, analyzed full text, conducted data collection, and performed assessment of study quality and risk of bias. In addition, part of the results were summarized through a random-effects meta-analysis. STRING database was used for protein-protein interaction analysis. Results Twenty-nine relevant studies were included. The ages of the subjects ranged from 2 to 89 years, with a mean age of 33.41 years. Twenty-two point two percent were female, 21.4% were male, and in 56.4% the gender of the participants was not specified. A total of 1,337 OL samples were analyzed for PDPN immunoexpression pattern. Ninety-four (7.03%) were dental follicles and germs, 715 (53.47%) were odontogenic cysts, and 528 (39.49%) were odontogenic tumors. Meta-analysis indicated that the immunostaining intensity was significantly stronger in odontogenic keratocysts compared to dentigerous cysts (SMD=3.3(CI=1.85-4.82, p=0.000*). Furthermore, bioinformatic analysis revealed that PECAM-1, TNFRF10B, MSN, EZR and RDX interact directly with PDPN and their expression in OL was demonstrated. Conclusions The results of the present systematic review support the unique immunoexpression of PDPN as a potential useful diagnostic marker in the pathogenesis of OL.

Published
2024
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245. Increased of IL-18 levels are associated with periodontitis: a systematic review and meta-analysis

Author

Mario Alberto Alarcón-Sánchez, Norma Samanta Romero-Castro, Julieta Sarai Becerra-Ruiz, Selenne Romero-Servin, and Artak Heboyan

Subjects
Interleukin 18, Serum, Plasma, Saliva, Gingival tissue, Gingival crevicular fluid, Dentistry, RK1-715
Abstract

Abstract Background The presence of a polymicrobial dysbiotic film in direct and constant contact with periodontal tissues initiates the host immune response. Interleukin 18 (IL-18) triggers up-regulates the production of other proinflammatory cytokines (TNF-α, IL-1β, IL-6), creating a vicious cycle that expands the inflammatory and destructive process in the periodontal tissue. A systematic review and meta-analysis was carried out with the main propose to investigate IL-18 expression in different biological samples from subjects with chronic periodontitis. Methods The protocol followed PRISMA guidelines and was registered in Open Science Framework (OSF): https://doi.org/10.17605/OSF.IO/BS9GM . A digital search was conducted in the databases PubMed, ScienceDirect, Google Scholar, Web of Science and Dentistry & Oral Sciences Source databases were consulted from March 15th, 2005 to February 10th, 2023. Study quality was assessed using the JBI tool for cross-sectional studies and clinical trials. A meta-analysis was performed using a random/fixed effects model to evaluate the concentration of IL-18 in serum, plasma, saliva, gingival tissue and GCF of exposure group compared to control group. Results The search strategy provided a total of 3,156 articles, of which 18 investigations met the inclusion criteria and 15 articles were quantitatively analyzed. The total number of patients studied was 1,275 (682 cases and 593 controls). The meta-analysis revealed significantly elevated IL-18 levels of serum, saliva and GCF of subjects with chronic periodontitis compared to healthy subjects (Serum: SMD = 62.73, 95%CI: 25.43-100.03, Z = 3.29, p = 0.001*; Saliva: SMD = 243.63, 95%CI: 8.68-478.59, Z = 2.03, p = 0.042*; GCF: SMD = 150.26, 95%CI: 56.86-243.66, Z = 3.15, p = 0.02*). Conclusion IL-18 levels in serum, saliva and GCF could have the potential to be used as complementary diagnostic tools to the clinical and radiographic parameters in subjects with periodontitis.

Published
2024
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246. Fasting before contrast-enhanced CT and the incidence of acute adverse reactions: a single-center randomized clinical trial

Author

Laila Zitan Saidi, Maricela Moreira Cabrera, Teresa Góngora Lencina, Fuensanta Marín Morón, Raquel Alarcón Rodríguez, and Jessica García González

Subjects
Fasting, Spiral computed tomography, Contrast media, Nausea, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Abstract Objectives To evaluate the effect of eliminating the traditional preparatory fasting policy before contrast-enhanced CT on acute adverse reactions and to identify potential risk factors in a Spanish population sample, since many European patients still experience this unnecessary measure in clinical practice. Methods Outpatients who underwent non-emergency CT to either 6 h of solid food fasting (control group) or an unrestricted consumption of solids (intervention group). Adverse reactions during contrast media administration and up to 30 min afterward were recorded and their incidence was calculated. Using univariate and multivariate logistic regression analyses, various patient-related and technical factors were evaluated to identify risk factors for nausea and vomiting. Results One thousand one hundred three patients were evaluated, 560 patients in the control group, and 543 patients in the intervention group. Moderate and severe acute adverse reactions were not identified in either group. No statistical difference was found in the overall acute adverse reactions (hypersensitivity and chemotoxicity) incidence between groups (3.21% vs 2.30% p = 0.36). The total incidence of emetic adverse reactions (nausea and vomiting) was significantly lower in the intervention group than in the control group (0.92% vs 2.86% p = 0.02). Multivariate logistic regression analysis revealed that fasting, age, allergies, neurological diseases, and contrast media concentration were independent risk factors for nausea and vomiting. Conclusion Unrestricted food intake did not increase the overall incidence of acute adverse reactions and diminished the incidence of nausea and vomiting. Trial registration ANZCTR, ACTRN12623000071628. Registered 23 January 2023—retrospectively registered, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=384985&showOriginal=true&isReview=true . Critical relevance statement This randomized clinical trial carried out in adults undergoing a non-emergent CT scan demonstrates that fasting as a preparation before a contrast-enhanced CT scan should be discontinued and reserved only for certain specific imaging tests. Key Points Despite low osmolar CT contrast media becoming ubiquitous, preparatory fasting is still widely practiced. The overall incidence of acute adverse reactions was unchanged after abolishing preparative fasting. Traditional preparatory fasting should be discontinued and reserved only for certain specific imaging tests. Graphical Abstract

Published
2024
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247. Salivary 8-hydroxy-2′-deoxyguanosine levels in patients with oral cancer: a systematic review and meta-analysis

Author

Mario Alberto Alarcón-Sánchez, Lilibeth-Stephania Escoto-Vasquez, and Artak Heboyan

Subjects
8-hydroxy-2′-deoxyguanosine, Saliva, Biomarkers, Squamous cell carcinoma of head and neck, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background DNA is an important target for oxidative attack and its modification may increase the risk of mutagenesis. The aim of this study was to evaluate and compare salivary levels of the oxidative stress biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) in patients with oral cancer (OC) compared to the control group by a comprehensive search of the available literature. Methods The present systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and was registered in Open Science Framework (OSF): https://doi.org/10.17605/OSF.IO/X3YMR. Four electronic databases were used to identify studies for this systematic review: PubMed, Scopus, ScienceDirect, and Web of Science from January 15, 2005, to April 15, 2021. The Joanna Briggs Institute (JBI) tool was used to assess article quality. Results Of the 166 articles identified, 130 articles were excluded on the basis of title and abstract screening (duplicates, reviews, etc.). Thirty-six articles were evaluated at full text and 7 articles met the inclusion criteria. Of these, only 5 studies had compatible data for quantitative analysis. An increase in salivary 8-OHdG levels was found in patients with OC compared to healthy subjects, but without statistical significance. 8-OHdG: SMD = 2,72 (95%CI= -0.25–5.70); *p = 0.07. Conclusions This systematic review and meta-analysis suggests a clear trend of increased 8-OHdG levels in saliva of OC patients compared to the control group. However, further studies are required to clarify and understand the altered levels of this oxidative stress marker.

Published
2024
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248. 'The effects of non-surgical periodontal treatment plus zinc and magnesium supplementation on oxidative stress and antioxidants enzymes in type 2 diabetes patients: a quasi-experimental study'

Author

José Carlos Alarcón-Moreno, Mónica Flores-Muñoz, María Sobeida L. Blázquez-Morales, Miguel Eric García-Rivera, Juan Carlos Rodríguez-Alba, Claudio Rafael Castro-López, Francisco Javier Nachón-García, Víctor Hugo Muñoz-Muñoz, and María Gabriela. Nachón-García

Subjects
Type 2 diabetes mellitus, Periodontal diseases, Non-surgical periodontal treatment, Zinc and magnesium, Antioxidant, Oxidative stress, Dentistry, RK1-715
Abstract

Abstract Background Periodontal Disease (PD) associated with Type 2 Diabetes Mellitus (T2DM) is a chronic condition that affects the oral cavity of people living with T2DM. The mechanisms of the interaction between type 2 Diabetes Mellitus and Periodontal diseases are complex and involve multiple pathophysiological pathways related to the systemic inflammatory process and oxidative stress. Non-surgical periodontal treatment (NSTP) is considered the standard for the management of this disease; however, patients with systemic conditions such as type 2 Diabetes Mellitus do not seem to respond adequately. For this reason, the use of complementary treatments has been suggested to support non-surgical periodontal treatment to reduce the clinical consequences of the disease and improve the systemic conditions of the patient. The use of zinc gluconate and magnesium oxide as an adjunct to non-surgical periodontal treatment and its effects on periodontal clinical features and oxidative stress in patients with Periodontal diseases -type 2 Diabetes Mellitus is poorly understood. Methods A quasi-experimental study was performed in patients with periodontal diseases associated with T2DM. Initially, 45 subjects who met the selection criteria were included. 19 were assigned to a control group [non-surgical periodontal treatment] and 20 to the experimental group (non-surgical periodontal treatment + 500 mg of magnesium oxide and 50 mg of zinc gluconate for oral supplementation for 30 days) and the data of 6 patients were eliminated. Sociodemographic characteristics, physiological factors, biochemical parameters, and clinical features of periodontal diseases were assessed. Results In this research a change in periodontal clinical characteristics was observed, which has been associated with disease remission. Additionally, a shift in MDA levels was presented for both groups. Furthermore, the supplementation group showed an increase in antioxidant enzymes when compared to the group that only received NSPT. Conclusion The use of Zinc gluconate and magnesium oxide can serve as a complementary treatment to non-surgical periodontal treatment, that supports the remission of PD as a result of regulation-reduction of oxidative biomarkers and increase in antioxidant enzymes activity. Trial Registration https://www.isrctn.com ISRCTN 14,092,381. September 13º 2023. Retrospective Registration. Graphical Abstract

Published
2024
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249. Integrated photon pairs source in silicon carbide based on micro-ring resonators for quantum storage at telecom wavelengths

Author

P. M. C. Tavares Ramírez, J. S. S. Durán Gómez, G. J. Rodríguez Becerra, R. Ramírez-Alarcón, M. Gómez Robles, and R. Salas-Montiel

Subjects
Medicine, Science
Abstract

Abstract We present the design of an on-chip integrated photon pair source based on Spontaneous Four Wave Mixing (SFWM), implemented on a ring resonator in the 4H Silicon Carbide On Insulator (4H-SiCOI) platform, compatible with a solid state quantum memory in the telecommunications band. Through careful engineering of the waveguide dispersion and micro-ring resonator dimensions, we found solutions where the signal photons are emitted at 1536.48 nm with a bandwidth of $$\sim 150$$ ∼ 150 MHz, enabling the interaction with the hyperfine structure of Er $$^{3+}$$ 3 + ions. Simultaneously, the idler photons are generated at 1563.86 nm, matching the central wavelength of a specific channel in a commercial dense wavelength division multiplexing system. The proposed device fulfill all the spectral requirements in a simple ring-bus coupled waveguide configuration with design parameters within the range of reported values for similar resonators, making feasible its manufacturing with current fabrication capabilities.

Published
2024
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250. Impacto de la tecnología BIM en la eficiencia y sostenibilidad de proyectos arquitectónicos

Author

Patricio Fernando Pérez Suárez, Diego Francisco Solano Zambrano, Sofía Lorena Sornoza Alarcón, and Evelyn Andrea Chérrez Córdova

Subjects
modelado de información de construcción (bim), eficiencia, sostenibilidad, proyectos arquitectónicos, integración de sistemas, colaboración multidisciplinaria, Architecture, NA1-9428
Abstract

El Modelado de Información de Construcción (BIM, por sus siglas en inglés) ha transformado radicalmente la industria de la arquitectura al permitir una gestión integral de proyectos desde su concepción hasta su mantenimiento. Este artículo explora el impacto de BIM en la eficiencia y sostenibilidad de los proyectos arquitectónicos. A través de una investigación exhaustiva y el análisis de casos de estudio, se demuestra que BIM mejora la coordinación entre equipos, reduce errores de diseño y facilita la integración de sistemas sostenibles. La adopción de BIM resulta en una mayor precisión en la fase de diseño, lo que conduce a una disminución de costos y tiempos de construcción. Además, BIM facilita la identificación y resolución temprana de conflictos, lo que promueve la eficiencia en la ejecución del proyecto. Igualmente, BIM contribuye a la sostenibilidad al permitir la simulación de impactos ambientales y la optimización de recursos energéticos. La colaboración multidisciplinaria es clave para aprovechar al máximo los beneficios de BIM, subrayando la importancia de la educación continua y la estandarización de procesos en la industria de la construcción. En conclusión, BIM se consolida como una herramienta esencial para el diseño y la construcción de edificios eficientes y sostenibles. A pesar de los desafíos persistentes, como la interoperabilidad de datos y la resistencia al cambio, es fundamental abordarlos para lograr la plena implementación de BIM en la práctica arquitectónica y constructiva.

Published
2024
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