Search

Background: Exercise interventions improve type 2 diabetes (T2D). Published randomised control trials and crossover control trials were systematically examined to establish the differences in the e...

The effects of breaking up sitting with resistance exercise on cardiometabolic health and cognitive function in young healthy adults are unknown. This study evaluated the acute effects of breaking up sitting with bodyweight resistance exercise on postprandial glucose, lipids, blood pressure and cognitive function. A randomised crossover design was used. Twelve normal-weight participants aged 25 ± 6 years took part in two, 5 h conditions: (1) uninterrupted sitting (SIT), and (2) sitting with 3 min of bodyweight resistance exercise breaks every 30 min (REX). Dietary intake was standardised across conditions. Linear mixed models were used to compare outcomes between conditions. Postprandial glucose was significantly higher in the REX condition than in SIT (incremental area under the curve 346.3 [95% confidence interval: 233.9, 458.7] and 256.9 [144.4, 369.3] mmol/L∙5 h, respectively, p = 0.045). Blood pressure, lipids and cognitive function outcomes were not different between conditions (p ≥ 0.05). This study suggests that breaking up sitting with bodyweight resistance exercise does not benefit cardiometabolic health or cognitive function acutely in young healthy adults. The longer-term effects of breaking up sitting with resistance exercise warrants investigation to appropriately inform public health guidelines.

Background. Cardiovascular disease (CVD) is closely related to arterial elasticity and hemodynamics. Exercises have been reported to immediately decrease arterial apparent elasticity and regulate hemodynamic variables. However, the relationship between them and exercise intensity remains elusive. The purpose of this study was to determine the acute effects of different intensities of acute cycling exercise on carotid arterial apparent elasticity and hemodynamics. Methods. 32 healthy men (age: 19.4 ± 0.6 years) attended the laboratory on five occasions and completed cycling acute exercise for 20 minutes at five intensities (40%, 50%, 60%, 70%, and 80% heart rate reserve (HRR)). At the right carotid artery, center-line velocity and arterial inner diameter waveforms were examined before and immediately after exercise. Based upon the measured data, the classical hemodynamic theory was used to calculate the apparent elasticity and the local hemodynamic variables. Results. The arterial apparent stiffness and the apparent elastic modulus following acute cycling exercise at 60% to 80% HRR were significantly higher than baseline. The mean center-line velocity accelerated from 50% to 80% HRR, but no intensity of intervention altered mean blood flow. Immediately after intervention, the mean wall shear stress and oscillatory shear index increased. Conclusions. Aerobic cycling intervention, with intensity from 40% to 80% HRR, did not change the brain blood supply. A bout of cycling intervention decreased apparent elasticity, and there was an intensity-dependent effect on apparent elasticity and hemodynamic variables. This study would provide referable data for the further study on the effects of aerobic exercise on arterial hemodynamics and elasticity and underlying physiological mechanisms.

Air pollution exposure leads to increased mortality and morbidity rates of respiratory diseases. Most of the evidence was founded on acute diseases such as acute lower respiratory diseases. However, limited studies have been conducted to evaluate the effects of air pollution on chronic respiratory diseases. This time-series study was conducted to examine the acute effects of 6 criteria ambient air pollutants on hospital outpatients with chronic rhinitis (CR) in Xinxiang, China. We retrieved 223,826 outpatient records of patients with respiratory diseases, of which 62,901 were those of patients with CR. Results showed that the current 10-μg/m3 increase in fine particulate matter (PM2.5), inhalable particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) corresponds to 0.67% (95% confidence interval [CI]: 0.15–1.18%), 0.58% (95% CI: 0.24–0.92%), 1.89% (95% CI: 0.52–3.27%), 3.01% (95% CI: 1.66–4.35%), and 0.06% (95% CI: 0.03–0.10%) increments in outpatients with CR, respectively. In addition, the effects in the male were stronger than those in the female. Higher effect estimates were observed in the old (≥ 65 years of age) and younger (

The acute effects of static stretching have been frequently studied, but the chronic effects have not been studied concurrently. Thus, this study aimed to investigate both the acute and chronic effects of static stretching at different intensities on flexibility. Twenty-three healthy men were randomly assigned to perform 1 min of static stretching 3 days/week for 4 weeks at 100% intensity (n = 12) or 120% intensity (n = 11). The acute effects of stretching were assessed by measuring the range of motion (ROM), peak passive torque, and passive stiffness before and after every stretching session; the chronic effects of stretching were assessed by measuring these outcomes at baseline and after 2 and 4 weeks of stretching. Compared with the 100% intensity group, the 120% intensity group had significantly greater acute increases in ROM after all 12 sessions, a significantly greater decrease in passive stiffness after 11 of 12 sessions, and a significantly greater increase in peak passive torque after six of 12 sessions. Regarding the chronic effects, ROM was significantly increased in both groups after 2 and 4 weeks of stretching. Peak passive torque significantly increased in the 100% intensity group after 2 and 4 weeks of stretching, and after 4 weeks in the 120% intensity group. Stretching at 120% intensity resulted in significantly greater acute improvements in ROM, peak passive torque, and stiffness than stretching at 100% intensity. Four weeks of stretching increased ROM and peak passive torque but did not decrease passive stiffness, regardless of the stretching intensity.

Members of socially marginalized communities have always suffered the most acute effects of natural disasters, and they have also been the slowest to recover. Thus, it is not surprising that the COVID-19 pandemic appears to be following a similar trajectory. This article details race disparities, social status and place, and their independent and combined effects on Americans' social and emotional health as COVID-19 infection rates began to accelerate across the country.

This study aimed to identify the acute effects of caffeinated chewing gum (CAF) on bicycle motocross (BMX) time-trial (TT) performance. In a randomized, placebo-controlled, double-blind cross-over design, 14 male BMX riders (age = 20.0 ± 3.3 years; height = 1.78 ± 0.04 m; body mass = 72 ± 4 kg), consumed either (300 mg; 4.2 ± 0.2 mg/kg) caffeinated (300 mg caffeine, 6 g sugars) or a placebo (0 mg caffeine, 0 g sugars) gum, and undertook three BMX TTs. Repeated-measure analysis revealed that CAF has a large ergogenic effect on TT time, F(1, 14) = 33.570, p = .001, ; −1.5% ± 0.4 compared with the placebo. Peak power and maximal power to weight ratio also increased significantly compared with the placebo condition, F(1, 14) = 54.666, p = .001, ; +3.5% ± 0.6, and F(1, 14) = 57.399, p = .001, ; +3% ± 0.3, respectively. Rating of perceived exertion was significantly lower F(1, 14) = 25.020, p = .001, in CAF (6.6 ± 1.3) compared with the placebo (7.2 ± 1.7). Administering a moderate dose (300 mg) of CAF could improve TT time by enhancing power and reducing the perception of exertion. BMX coaches and riders may consider consuming CAF before a BMX race to improve performance and reduce rating of perceived exertion.

Aims It is unclear whether night-time noise events, including from aeroplanes, could trigger a cardiovascular death. In this study, we investigate the potential acute effects of aircraft noise on mortality and the specific role of different night-time exposure windows by means of a case-crossover study design. Methods and results We selected 24 886 cases of death from cardiovascular disease (CVD) from the Swiss National Cohort around Zürich Airport between 2000 and 2015. For night-time deaths, exposure levels 2 h preceding death were significantly associated with mortality for all causes of CVD [OR = 1.44 (1.03–2.04) for the highest exposure group (LAeq > 50 dB vs., Graphical Abstract

We aimed to evaluate the acute physiological effects of high-load barbell back squat exercise on each lumbar intervertebral disk with varying squat depths. Thirteen subjects (age, 23.3 ± 3.5 years) performed parallel and half-squat exercises (80% of one repetition maximum, eight repetitions, five sets) using a Smith machine. Sagittal magnetic resonance diffusion-weighted and spin-echo images of lumbar intervertebral disks were obtained by using a 1.5-Tesla MR system before and after each squat exercise; apparent diffusion coefficient (ADC; an index of water movement) and T2 relaxation time (an index of water content level) of the nucleus pulposus were calculated at all lumbar intervertebral disks. Additionally, we measured the angles of lumbar lordosis and anterior pelvic tilt at the bottom position of each squat using a three-dimensional motion-capture system. The nucleus pulposus of L4/5 (-5.0%, P < .01) and L5/S1 (-6.6%, P < .01) intervertebral disks showed decreased ADC values after parallel squat exercise. Moreover, post-exercise ADC value in parallel squat exercise was lower than that in half-squat exercise at L5/S1 intervertebral disk (P < .05). In contrast, the nucleus pulposus of all lumbar intervertebral disks had no significant T2 change before and after both squat exercises. The angles of lumbar lordosis (P < .01) and anterior pelvic tilt (P < .01) were smaller in parallel squat than in half-squat. Lower lumbar intervertebral disks are subject to greater mechanical stress during high-load parallel back squat exercise, which may result from smaller lumbar lordosis and anterior pelvic tilt angles at the bottom position during parallel squat.

Background. The current study investigated the effect of dipping tobacco (DT) use on arterial wall stiffness which is a known marker of increased risk of cardiovascular events. Methods. A case-control study which included 101 adult males was carried out in Al-Shaab Teaching Hospital. Blood pressure and pulse wave analysis parameters were recorded in 51 DT users (study group) before and after 30 minutes of placing tobacco and in 50 nontobacco users (control group). Anthropometric measurements were collected using data collection sheet. Data were entered into a computer and analyzed by using the software Statistical Package for the Social Sciences (SPSS) version 20 (SPSS Inc., Chicago, IL, USA). Results. At baseline measurements, heart rate (HR) was significantly lower in the study group compared to the control group ( 66.15 ± 9.21 vs. 72.87 ± 10.13 beats/min; P value ≤ 0.001). Subendocardial viability ratio (SEVR) was significantly higher in the study group compared to the control group ( 203.44 ± 30.34 vs. 179.11 ± 30.51 % ; P value ≤ 0.001). Acute effects of DT compared to pretobacco dipping showed significant increase in HR ( 72.50 ± 10.89 vs. 66.15 ± 9.21 beats/min; P value ≤ 0.001) and significant decrease in augmentation pressure (AP) (4.30 (2.30-8.00) vs. 3.30 (0.60-6.3) mmHg; P value ≤ 0.001), ejection duration (ED) ( 271.65 ± 19.42 vs. 279.53 ± 20.47 ms ; P value ≤ 0.001), and SEVR ( 187.11 ± 29.81 vs. 203.44 ± 30.34 ; P value ≤ 0.001). Linear regression analysis for AP predictor showed that only HR and AIx@75 affect and predict the values of AP ( Beta ± SE ; − 0.242 ± 0.019 , P value ≤ 0.001; 0.685 ± 0.014 , P value ≤ 0.001). Conclusions. Long-term use of DT was not associated with permanent changes in heart rate and blood pressure. Acute tobacco dipping caused an acute increase in heart rate and oxygen demands of myocardium.

Post workout multi-ingredient admixtures are commonly used to maximize recovery after exercise. The present double-blind, cross-over study compared the acute effects of ingesting a protein-vegan multi-ingredient (VGMT) vs. maltodextrin (MALT) on indices of muscle function. Ten trained males, (26.8 ± 1.9 years) performed two identical, 3-day resistance training periods (one workout-session per day) while receiving either VGMT or MALT (10 min after the completion of each workout). Following a baseline evaluation, we conducted assessments at, 1-h, 24-h and 48-h after the 3-day training period. Primary outcome included the evoked tensiomyography contraction velocity (Vc) of vastus medialis (VM), biceps femoris long head (BFLH) and anterior deltoids (AD). Secondary outcomes involved strength and power performance while the other tensiomyography variables [muscle displacement (Dm), contraction time (Tc)] were considered as exploratory. After 1-h, all the tensiomyography variables measured at VM and BFLH were similarly depressed in both treatments. Only MALT showed a significantly lower Vc (-0.02 m.s-1, 95% CI, -0.04, -0.01) in the AD. After 24-h, the VGMT treatment normalized all tensiomyography values. Conversely, impaired scores were observed in Vc for the VM (-0.03 m.s-1, 95% CI, -0.06, -0.01) and BFLH (-0.02 m.s-1, 95% CI, -0.05, 0.01) in the MALT treatment. Particularly, the Vc in VM was lower (p = 0.043) in MALT compared to VGMT. Overall, both treatments required 48-h to regain their performance capacity; however, VGMT produced better vertical jump and squat performance at 24-h vs. MALT. Compared to MALT, a vegan-protein multi-ingredient appears to hasten the recovery of muscular function over a 24-h period. Sin financiación No data JCR 2020 0.526 SJR (2020) Q2, 122/332 Food Science No data IDR 2020 UEM

OBJECTIVE This three-armed randomized controlled feasibility trial tested the acceptability and acute effects of aerobic exercise and technology-guided mindfulness training (relative to standalone interventions) on cancer-related fatigue among breast cancer survivors (BCS). METHODS BCS recruited from Central Illinois completed pre- and post-testing using established measures and were randomized to one of three groups (combined aerobic exercise with guided-mindfulness relaxation, aerobic exercise only, and relaxation only), conducted in three 90 min sessions over the course of 7 days in a fitness room and research office on a university campus. RESULTS We enrolled 40 BCS (Mage = 57.33 ± 8.75), MBMI = 27.38 ± 5.27, Mfatigue = 4.56 ± 1.81 as measured by the Piper Fatigue Scale. More favorable post-intervention evaluations were reported by the combined group, compared to aerobic exercise or relaxation only (p < 0.05). Reductions in fatigue favoring the combined group (p = 0.05) showed a modest effect size (Cohen's d = 0.91) compared to aerobic exercise only. CONCLUSIONS These findings provide preliminary evidence for the feasibility of combining evidence-based techniques to address fatigue among BCS. The combined approach, incorporating mobile health technology, presents an efficacious and well-received design. If replicated in longer trials, the approach could provide a promising opportunity to deliver broad-reaching interventions for improved outcomes in BCS. Preregistered-ClinicalTrials NCT03702712.

In recent years there has been great interest in the effects of exercise on cognition, but few have investigated whether physical activity influences risk-taking. Purpose: To investigate the effect...

BACKGROUND: Patients with decreased consciousness are prone to prolonged bed rest and respiratory complications. If effective in reducing atelectasis, lung expansion maneuvers could be used to prevent these complications. In comatose, bedridden subjects, we aimed to assess the acute effect on regional lung aeration of 2 lung expansion techniques: expiratory positive airway pressure and the breath-stacking maneuver. Our secondary aim was to evaluate the influence of these lung expansion techniques on regional ventilation distribution, regional ventilation kinetics, respiratory pattern, and cardiovascular system. METHODS: We enrolled 10 subjects status post neurosurgery, unable to follow commands, and with prolonged bed rest. All subjects were submitted to both expansion techniques in a randomized order. Regional lung aeration, ventilation distribution, and regional ventilation kinetics were measured with electrical impedance tomography. RESULTS: Lung aeration increased significantly during the application of both expiratory positive airway pressure and breath-stacking (P < .001) but returned to baseline values seconds afterwards. The posterior lung regions had the largest volume increase (P < .001 for groups). Both maneuvers induced asynchronous inflation and deflation between anterior and posterior lung regions. There were no significant differences in cardiovascular variables. CONCLUSIONS: In comatose subjects with prolonged bed rest, expiratory positive airway pressure and breath-stacking promoted brief increases in lung aeration. (ClinicalTrials.gov registration NCT02613832.)

Aerosol particles have been shown to trigger cardiovascular and respiratory diseases in populations living in polluted regions, depending on their size and composition. Although fine aerosol particles have been found to reach the lungs and the blood stream, their acute effects are related to the fraction of ultrafine aerosol particles (i.e., UFPs, d 0.03 μm), PM10, PM2.5, criteria gases, and meteorological variables, were also monitored. The average UFPs concentration over the full sampling period was found to be 2,070 ± 1,831 cm-3, with events of peak concentrations as high as 55,117 cm−3. The average daily UFP profile is bimodal, with peak concentrations observed around 07:00 and 20:00 h LT. The correlation of the UFP with other measured variables suggests that the UFPs peaks observed in the morning and at night are likely caused by primary vehicular combustion particles. In contrast, atypical high concentrations of UFPs were occasionally observed around noon LT, which are likely of secondary origin and the result of new particle formation promoted by photochemistry. Overall, UFPs are the major contributor to the total particle number concentration, and they are likely an important contributor to PM2.5 in Merida during the morning hours, with clear anthropogenic sources.

Chen, WH, Yang, WW, Lee, YH, Wu, HJ, Huang, CF, and Liu, C. Acute effects of battle rope exercise on performance, blood lactate levels, perceived exertion, and muscle soreness in collegiate basketball players. J Strength Cond Res 34(10): 2857-2866, 2020-This study investigated the acute effects of battle rope (BR) exercise on basketball players' performance, blood lactate levels, rating of perceived exertion (RPE), and perceived muscle soreness. Fifteen well-trained Division-I male basketball players underwent the same test procedure at baseline, before BR exercise (30 minutes of rest after the baseline test), and after BR exercise. The 30-minute experimental protocol comprised 6 BR exercises at a work-to-rest ratio of 1:2 (20-second exercise and 40-second rest). Shooting accuracy, basketball chest pass speed, countermovement jump (CMJ) height, blood lactate levels, RPE (Borg Category-Ratio-10 scale), and perceived muscle soreness (visual analog scale, 0-100 mm) were measured in each test. The results indicated no change for any variables between baseline and before BR exercise. After BR exercise, performance decrements (p < 0.05) were recorded in shooting accuracy (16.9%) and basketball chest pass speed (9.1%), but no significant changes were observed for CMJ height. Battle rope exercise caused increases in blood lactate levels (13.6 mmol·L), RPE (9.9), and perceived muscle soreness (upper-limb: 63-67 mm; trunk: 43-68 mm; and lower-limb: 45-52 mm). In conclusion, BR exercise is physically demanding on the upper body, resulting in decreased performance in shooting accuracy and basketball chest pass speed. Battle rope exercise may not be beneficial before a practice or game because it triggers acute exercise-induced performance decrements and fatigue. However, BR exercise may be suitable for basketball training sessions in which the objective is to strengthen technical skills under fatiguing conditions.

BACKGROUND: Low-frequency oscillations (LFO) detected in the internal globus pallidus of dystonia patients have been identified as a physiomarker for adaptive Deep Brain Stimulation (aDBS), since LFO correlate with dystonic symptoms and are rapidly suppressed by continuous DBS (cDBS). However, it is as yet unclear how LFO should be incorporated as feedback for aDBS.OBJECTIVES: to test the acute effects of aDBS, using the amplitude of short-lived LFO-bursts to titrate stimulation, to explore the immediate effects of cDBS on LFO-modulation and dystonic symptoms, and to investigate whether a difference in the resting-state LFO is present between DBS-naïve patients and patients with chronic DBS.METHODS: seven patients were assessed during either DBS-implantation (n = 2) or battery replacement surgery (n = 5), and pseudorandomized in three conditions: no stimulation, cDBS, and aDBS. Additionally, resting-state LFP-recordings from patients undergoing battery replacement were compared to those obtained during DBS-implantation; LFP-recordings from a previous cohort of six dystonia patients undergoing DBS-implantation were incorporated into this analysis (total n = 8 newly implanted patients).RESULTS: we corroborated that a mild LFO-suppression rapidly occurs during cDBS. However, no acute changes in clinical symptoms were observed after cDBS or aDBS. Remarkably, we observed that resting-state LFO were significantly lower in patients who had been effectively treated with chronic cDBS compared to those of newly implanted patients, even when stimulation was suspended.CONCLUSIONS: our results indicate that LFO-suppression in dystonia, similar to symptom response to cDBS, might be gradual, and remain after stimulation is suspended. Therefore, tracking gradual changes in LFO may be required for aDBS implementation.

Complex regional pain syndrome (CRPS) is one of the common complications in stroke patients. Sympathetic dysfunction is usually considered underlying pathology. The evidence for contrast bath (CB) used in the treatment of CRPS is limited. The aim of the study is to investigate the possible effects of CB on the sympathetic activity in poststroke CRPS.Stroke patients with CRPS (CRPS group) and without CRPS (control group) were included in the study. Age, gender, duration of stroke, aetiology, plegic side, dominant hand, spasticity level, Brunnstrom stages, and comorbidities were recorded. CB was performed for one session to the plegic side of the CRPS and control groups. Sympathetic skin responses (SSR) was recorded from the plegic and healthy hands of participants at pre-CB and post-CB.Each group consisted of 20 participants. No significant difference was detected in stroke duration, aetiology, and Brunnstrom stages between groups. Elbow spasticity level was significantly higher in CRPS groupCB leads to a significant reduction in sympathetic activity of plegic side of stroke patients. Also, CB to the plegic side has an inhibitory effect on sympathetic activity of healty side in poststroke CRPS.

Eccentric quasi-isometric (EQI) contractions have been proposed as a novel training method for safely exposing the musculotendinous system to a large mechanical load/impulse, with few repetitions. However, understanding of this contraction type is rudimentary. We aimed to compare the acute effects of a single session of isotonic EQIs with isokinetic eccentric (ECC) contractions. Fifteen well-trained men performed a session of impulse-equated EQI and ECC knee extensions, with each limb randomly allocated to one contraction type. Immediately PRE, POST, 24/48/72 h, and 7 days post-exercise, regional soreness, quadriceps swelling, architecture, and echo intensity were evaluated. Peak concentric and isometric torque, rate of torque development (RTD), and angle-specific impulse were evaluated at each time point. There were substantial differences in the number of contractions (ECC: 100.8 ± 54; EQI: 3.85 ± 1.1) and peak torque (mean: ECC: 215 ± 54 Nm; EQI: 179 ± 28.5 Nm). Both conditions elicited similar responses in 21/53 evaluated variables. EQIs resulted in greater vastus intermedius swelling (7.1–8.8%, ES = 0.20–0.29), whereas ECC resulted in greater soreness at the distal and middle vastus lateralis and distal rectus femoris (16.5–30.4%, ES = 0.32–0.54) and larger echogenicity increases at the distal rectus femoris and lateral vastus intermedius (11.9–15.1%, ES = 0.26––0.54). Furthermore, ECC led to larger reductions in concentric (8.3–19.7%, ES = 0.45–0.62) and isometric (6.3–32.3%, ES = 0.18–0.70) torque and RTD at medium-long muscle lengths. A single session of EQIs resulted in less soreness and smaller reductions in peak torque and RTD versus impulse-equated ECC contractions, yet morphological shifts were largely similar. Long-term morphological, architectural, and neuromuscular adaptations to EQI training requires investigation.

The aim of this study was to investigate the acute effects of p-synephrine ingestion on substrate oxidation during exercise in elite cyclists. Fifteen elite cyclists volunteered to participate in a double blind, crossover, randomized and placebo-controlled experimental trial. During two different trials, participants either ingested a placebo (cellulose) or 3 mg/kg of p-synephrine. After 60 min for substances absorption, participants performed an incremental maximal cycle ergometer test until volitional fatigue (25 W/min). Breath-by-breath gas exchange data was continuously recorded during the entire test to estimate energy expenditure, carbohydrate oxidation, and fat oxidation rates by stoichiometric equations. Heart rate was continuously measured by using a heart rate monitor. The ingestion of p-synephrine had no significant effects on energy expenditure (F = 0.71, P = 0.40) or heart rate (F = 0.66, P = 0.43) during exercise. However, there was a main effect of p-synephrine to increase the rate of fat oxidation over the placebo (F = 5.1, P = 0.04) and the rate of fat oxidation was higher with p-synephrine in the following loads: 45 ± 2%, 51 ± 3%, 62 ± 3%, 67 ± 4%, 79 ± 5% and 85 ± 5% of the maximum wattage obtained in the test (all P

Long-term exposure to fine particulate matter (PM2.5) is associated with kidney dysfunction. However, few studies have investigated acute effects of PM2.5 elemental constituents on renal function. We evaluated associations between personal PM2.5 and its elemental constituents and kidney function, assessed by an estimated glomerular filtration rate (eGFR) in Biomarkers of Air Pollutants Exposure in the Chinese aged 60-69 study. Seventy one older individuals were visited monthly between September 2018 and January 2019. Each participant wore a PM2.5 monitor for 72 h, responded to a questionnaire, and underwent a physical examination with blood sampling. Linear mixed-effect models were used to estimate associations between personal PM2.5 elemental constituents and eGFR. We found that significant changes in eGFR from -1.69% [95% confidence interval (CI): -3.34%, -0.01%] to -3.27% (95% CI: -5.04%, -1.47%) were associated with interquartile range (IQR) increases in individual PM2.5 exposures at various lag periods (7-12, 13-24, 0-24, 25-48, and 49-72 h). An IQR increase in 72 h moving averages of copper, manganese, and titanium in personal PM2.5 corresponded to -2.34% (95% CI: -3.67%, -0.99%) to -4.56% (95% CI: -7.04%, -2.00%) changes in eGFR. Personal PM2.5 and some of its elemental constituents are inversely associated with eGFR in older individuals.

BackgroundPhysical exercise improves mental health and cognitive function. The purpose of this systematic review was to evaluate the current literature examining the acute effects of a single exercise workout on learning and memory functions in young adults. MethodsThe review was conducted in alignment with the PRISMA guidelines. Studies were included if they were indexed in PubMed, published between 2009 and 2019, used an experimental study design and conducted on young human adults. The MeSH terms "exercise," "learning," and "young adults" were used together with the filters Publication dates-10 years; Human Species; and Article types-Clinical Trial. ResultsThirteen studies met the inclusion criteria and were evaluated. The types of exercise stimulus that were used was walking, running, or bicycling. Several different test instruments were used such as Rey Auditory Verbal Learning Test, Trail Making Test A and B, and Stroop Color Word Test. Exercise for two minutes to one hour at moderate to high intensity had a favorable effect on learning and memory functions in the selected studies. ConclusionsThis systematic review shows that aerobic, physical exercise before encoding improves learning and memory functions in young adults.

Regular exercise in moderate intensities and for moderate durations has been very effective in promoting functional health and disease prevention capacity. However, in the recent past several motivated individuals are trying to involve in high intensity and very long duration aerobic dominant activities like marathon running, ultra-endurance cycling etc to enhance their health fitness and functional health. Though the general perception is that exercise is a positive tool in bringing positive changes in the health, the exercise seems a stressful activity which also promotes oxidative and inflammatory damages. Especially the high intensity and very long duration and sustained activities like marathon running may induce uncontrolled or excessive oxidative and inflammatory processes that might compromise the whole-body immunity and specially in acute conditions, the immediate effect may be on the respiratory tract physiology. Recreational runners who are taking up running as their favourite physical activity to promote health may not prepare adequately to tackle these negative pathological processes and may prone for frequent respiratory infections. It is more specifically important for the women recreational runners, as their immune suppression may be much aggressive due to these acute high intensity exercises like marathon training. It is important for the women recreational runners as most of them are aged, need to regularly monitor their upper respiratory tract health through credible quantification techniques and also should adopt excellent strategies of training and recovery like scientific physical training before the event and also the excellent nutritional strategies.

Stretching exercises conducted by oneself, herein referred to as self-stretching exercises, improve arterial stiffness in healthy people. Such exercises include voluntary contraction of peripheral muscles in addition to stretching of target muscles. However, the effects of static passive stretching without voluntary contraction of skeletal muscles on arterial stiffness remain unknown. In addition, it is important to verify the effects of stretching in the elderly lacking exercise habits with advanced arterial stiffness. Therefore, the purpose of the present study was to verify the acute effects of static passive stretching, without voluntary contraction of skeletal muscles, on the cardio-ankle vascular index (CAVI) in elderly individuals lacking exercise habits. The present study followed a pretest-posttest design without a control group. Twenty-nine elderly individuals (mean age, 77.8 ± 7.0 years; 24 female) recruited at an orthopedic clinic participated in the present study. The participants were subjected to static passive stretching of the neck, trunk, and extremities for 40 min by the same physical therapist. Stretching involved the shoulder flexors/extensors, elbow flexors/extensors, wrist palmar flexors/dorsal flexors, hip flexors/extensors/adductors, knee flexors/extensors, ankle plantar flexors/dorsal flexors, neck muscles, and trunk muscles. The CAVI (Rt, Lt, Ave), ankle-brachial index (ABI), blood pressure, and pulse rate were assessed before and after stretching. After stretching, both CAVI (Lt, Ave) and pulse rate were significantly decreased. In contrast, no significant changes in CAVI (Rt), ABI, or blood pressure were observed. The key new finding of the present study was that static passive stretching without voluntary contraction of skeletal muscles acutely improved the CAVI in elderly individuals lacking exercise habits.

Morawetz, D, Blank, C, Koller, A, Arvandi, M, Siebert, U, and Schobersberger, W. Sex-related differences after a single bout of maximal eccentric exercise in response to acute effects: a systematic review and meta-analysis. J Strength Cond Res 34(9): 2697-2707, 2020-The most prominent effects after unaccustomed eccentric exercise are muscle damage, muscle soreness, strength loss, and higher concentrations of muscle proteins in the plasma. The aim of this systematic review is to evaluate sex-related differences in these acute effects. A systematic literature search in MEDLINE following the PRISMA guidelines was performed. Inclusion criteria were the difference in absolute outcomes between sexes in eccentric muscle strength, strength loss after eccentric exercise, blood concentrations of creatine kinase (CK), and delayed onset muscle soreness (DOMS). Results for maximal eccentric torque and CK data were pooled using a random-effect meta-analysis. A meta-regression was conducted to explain heterogeneity. Based on the 23 included trials, men showed significantly higher absolute eccentric strength. No sex-related differences were detected when normalizing strength for body mass, cross-sectional area of the muscle, or fat-free mass. Women displayed a tendency toward greater relative strength loss immediately after exercise. The absolute CK concentrations of men were significantly higher after exercise-induced muscle damage. No significant difference was found between sexes in DOMS. Untrained men and women display similar responses in all measures of relative muscle strength and DOMS. Apart from the enzymatic activity after exercise and the levels of absolute eccentric torque, there is no evidence for sex-related differences immediately after eccentric exercise. Therefore, eccentric training might have the same impact on men and women. One potential sex difference with practical relevance would be the possible difference in fatigue pattern immediately after eccentric exercise.

Background and Study Aim: The aim of this study is to investigate acute effects of different warm-up and stretching protocols, on 30 m. sprint, flexibility, vertical jump, strength, balance and anaerobic power performances in junior male judokas. Material and Methods: Twenty sub-elite 11-14 year old judokas who volunteered to participate in the study (age: 12,25±0,96 years; height: 1,52±0,11cm; body mass: 48,06±14,22 kg). This study consist of four different stretching and warm up protocols; without stretching (WS); static stretching (SS); dynamic warm up (DW); dynamic+static warm up (DSW). Results: The effect of the four stretching and warm up protocols were analysed by an ANOVA for repeated measures (WS x SS x DW x DSW). After stretching and warm up protocols, 30 m. sprint values are statistically significance (p0.05). There was only significant difference is found between WS and SS (p0.05), there was found significant differences between WS and DSW, SS and DSW in favour of DSW (p

Photobiomodulation therapy (PBMT) has been used to improve the physical performance of individuals with advanced age; however, there are no studies in the literature that support the application of light-emitting diode (LED) therapy for the muscular performance of individuals with diabetes mellitus who show a decline in functionality. The aim of the study was to analyze the acute effects of PBMT on strength and functional performance in type 2 diabetic individuals. Sixty-three volunteers were recruited and randomized into five groups: control (C), sham (S), red LED (R), infrared LED (IR), and red LED + infrared LED (R + IR). On the first day, the volunteers were evaluated using the time up and go (TUG), the 6-min walk test (6MWT), and isokinetic dynamometer of the ankle. In the following 3 days, groups R, IR, R + IR, and S returned for application of PBMT bilaterally, with 180 J of energy on each leg. On the fifth day, a reassessment was performed. There was no statistical difference between groups for the variables of the isokinetic dynamometer, TUG, and 6MWT. Analysis of the size of the clinical effect for the isokinetic variables showed that there was no pattern among the effects observed. There is a moderate effect in favor of R, IR, and R + IR in relation to C for the TUG and a moderate effect of R + IR in relation to C for the 6MWT. The PBMT applied for a short period does not bring important gains for the muscular performance and functionality of diabetic individuals.

Aim: Early intravenous use of b-blockers within the first hours of STEMI is less firmly established. The aim of this study was to evaluate the effect of esmolol on left ventricular (LV) haemodynamic, rotational and strain parameters in intact myocardium and early post an experimental acute anterior myocardial infarction (MI). Methods: In 20 healthy pigs LV torsional and strain parameters were calculated from basal and apical short axis epicardial planes with speckle tracking technique using EchoPAC platform. LV measurements at baseline and during esmolol infusion (0.5 mg/kg for 1 min, then 0.05 mg/kg/min for 5 min) were compared in intact myocardium and repeated without b-blocker and during esmolol infusion 2 hours post LAD ligation. Results: LV function was highly dependent on the esmolol infusion, in the intact and even more in the infarcted myocardium. LV ejection fraction, LV dP/dtmax and LV end-systolic pressure decreased significantly, a deterioration produced by the administration of esmolol. Torsion-twist and untwisting rate also presented significant reduction in correlation with ejection fraction and cardiac output, appearing to affect especially the apex torsional and strain parameters. Conclusion: Esmolol infusion significantly reduces LV haemodynamic, torsional and strain parameters in intact myocardium and early post MI. These results suggest that early intravenous use of esmolol in patients with STEMI is risky and it is prudent to wait for the patient to stabilize before starting esmolol.

The purpose of the present study was to evaluate the acute effects of single session of body-weight resistance exercises on blood pressure (BP) and glycemia in middle-aged adults with hypertension.Twenty-three participants took part in this trial with crossover design and performed two experimental sessions in a random order: Body-weight resistance exercise session (BWR) and a control session without exercise. BWR was composed of four exercises: inverted row, squat, , and sit-ups. The participants performed 3 sets of 30 s, in which they were instructed to perform as much repetitions as possible and as fast as possible. After each session, BP and glycemia were measured continuously for 60 min.Systolic BP decreased after BWR when compared with control at post 45': -7 (95%CI:-11 to -2) mmHg,BWR acutely reduces BP in middle-aged adults with hypertension without effects on usual glycemia responses. This alternative form of resistance training could facilitate access, adherence, and reduce health costs related to exercise programs.

Background: Cannabidiol has potential therapeutic benefits for people with psychiatric disorders characterised by reward function impairment. There is existing evidence that cannabidiol may influence some aspects of reward processing. However, it is unknown whether cannabidiol acutely affects brain function underpinning reward anticipation and feedback. Hypotheses: We predicted that cannabidiol would augment brain activity associated with reward anticipation and feedback. Methods: We administered a single 600 mg oral dose of cannabidiol and matched placebo to 23 healthy participants in a double-blind, placebo-controlled, repeated-measures design. We employed the monetary incentive delay task during functional magnetic resonance imaging to assay the neural correlates of reward anticipation and feedback. We conducted whole brain analyses and region-of-interest analyses in pre-specified reward-related brain regions. Results: The monetary incentive delay task elicited expected brain activity during reward anticipation and feedback, including in the insula, caudate, nucleus accumbens, anterior cingulate and orbitofrontal cortex. However, across the whole brain, we did not find any evidence that cannabidiol altered reward-related brain activity. Moreover, our Bayesian analyses showed that activity in our regions-of-interest was similar following cannabidiol and placebo. Additionally, our behavioural measures of motivation for reward did not show a significant difference between cannabidiol and placebo. Discussion: Cannabidiol did not acutely affect the neural correlates of reward anticipation and feedback in healthy participants. Future research should explore the effects of cannabidiol on different components of reward processing, employ different doses and administration regimens, and test its reward-related effects in people with psychiatric disorders.

Context: People with patellofemoral pain (PFP) present altered lower-limb movements during some activities. Perhaps, joint misalignment in the hip is one of the reasons for altered movement patterns in people with PFP. Some mobilization techniques have been designed to address joint misalignments. Objective: To investigate the acute effects of hip mobilization with movement (MWM) technique on pain and biomechanics during squats and jumps in females with and without PFP. Design: Randomized, placebo-controlled trial. Setting: Movement analysis laboratory. Patients: Fifty-six physically active females (28 with PFP and 28 asymptomatic) were divided into 4 groups: experimental group with PFP, sham group with PFP, experimental group without PFP, and sham group without PFP. Intervention(s): The experimental groups received MWM for the hip, and the sham groups received sham mobilization. Main Outcome Measures: Pain, trunk, and lower-limb kinematics, and hip and knee kinetics during single-leg squats and landings. Results: After the interventions, no difference between groups was found for pain. The PFP experimental group decreased hip internal rotation during squats compared with the PFP sham group (P = .03). There was no other significant difference between PFP groups for kinematic or kinetic outcomes during squats, as well as for any outcome during landings. There was no difference between asymptomatic groups for any of the outcomes in any of the tasks. Conclusions: Hip mobilization was ineffective to reduce pain in people with PFP. Hip MWM may contribute to dynamic lower-limb realignment in females with PFP by decreasing hip internal rotation during squats. Therefore, hip MWM could be potentially useful as a complementary intervention for patients with PFP.

Background: Recent evidence has suggested that chronic physical activities including balance exercises have positive effects on cognition, but their acute effects are still unknown. In the present study, the authors tested the hypothesis that an acute bout of balance exercise would enhance cognitive performance compared with aerobic activity. Methods: A total of 20 healthy middle-aged adults completed 2 acute 30-minute balance and moderate-intensity aerobic exercise sessions on 2 counterbalanced separate occasions. To assess cognitive functions, performance tasks in executive control, perceptual speed, and simple reaction time were tested before and immediately after each exercise session. Results: Although there were no significant interactions (time × exercise condition, P > .05), the main effects of time were significant in executive control (P P P Conclusions: These findings highlight that both types of exercise (aerobic, more metabolic and less cognitively demanding; balance, more cognitively and less metabolically demanding) were able to positively affect simple reaction time performance, perceptual speed, and executive control independently of physiological adjustments occurring during aerobic or balance exercise.

Lockhart, C, Scott, BR, Thoseby, B, and Dascombe, BJ. Acute effects of interset rest duration on physiological and perceptual responses to resistance exercise in hypoxia. J Strength Cond Res 34(8): 2241-2249, 2020-This study aimed to determine whether manipulating interset rest periods during resistance training in hypoxia impacts on physiological and perceptual responses to exercise. Twelve healthy males completed 1 repetition maximum (1RM) testing for the bilateral leg extension, before completing 4 separate randomized trials comprising 5 × 10 repetitions of leg extensions at 70% 1RM. Experimental trials were completed in both moderate hypoxia (FIO2 = 15%) and normoxia (FIO2 = 21%), using interset rest periods of both 60 and 180 seconds for each environmental condition. Near-infrared spectroscopy was used to quantify muscle oxygenation of vastus lateralis , and surface electromyography assessed the activation of vastus lateralis and medialis. Blood lactate concentration ([BLa]) and midthigh circumference were assessed before and immediately after each trial. Heart rate (HR) responses, blood oxygen saturation, and rating of perceived exertion (RPE) were also assessed after each set and the whole session RPE (sRPE). Perceived quadriceps soreness was reported before, immediately after, and at 24 and 48 hours after each trial. Muscle activation (sets 4-5), RPE (sets 3-5), and sRPE were significantly (p < 0.05) higher in the 60-second trials of the resistance exercise protocol. Significant increases (p < 0.01) were observed for [BLa] and midthigh circumference across sets within each condition. No significant main effect was observed for interset rest duration or environmental condition for muscle oxygenation, HR, or perceived quadriceps soreness. These findings indicate that performing resistance exercise in hypoxia or normoxia with shortened interset rest periods increases muscle activation and perceived exertion, without exacerbating muscle soreness.

El ejercicio físico puede tener efectos beneficiosos sobre las funciones cognitivas y el rendimiento académico. Entre las funciones cognitivas, el estudio de la atención en escolares ha adquirido un especial interés por su posible influencia en aspectos concretos tales como el rendimiento académico o la integración social. El objetivo fue analizar el efecto agudo de una sesión de ejercicio físico aeróbico sobre la atención selectiva en una muestra de 48 niños y 40 niñas (Edad, M ± DT = 9.48 ± .505 años). Se empleó un diseño de estudio cuasi-experimental con un grupo control y otro experimental. El ejercicio físico consistió en recorrer una milla lo más rápidamente posible. Se midió la atención selectiva con el Test de Caras. El grupo experimental se dividió en dos subgrupos (menor v. mayor) según el tiempo empleado en la milla. Los resultados mostraron diferencias significativas en aciertos (p = .012), control inhibitorio (p = .020) y omisiones (p = .007) tras la intervención. Se detectó una correlación inversa entre el tiempo empleado en el ejercicio físico y aciertos (p = .022). El análisis de la varianza detectó registros superiores en aciertos (p = .047) en el grupo con menor tiempo empleado. Los resultados sugieren que la realización de una sesión de ejercicio físico aeróbico de corta duración podría tener efectos agudos positivos en la atención selectiva. La realización en menor tiempo de un ejercicio físico como la milla se relaciona con una mejor atención selectiva. Tener una mejor capacidad aeróbica podría relacionarse con una mayor atención selectiva. Abstract. Physical exercise can have beneficial effects on cognitive functions and academic performance. Among cognitive functions, the study of attention in schoolchildren has acquired special interest due to its possible influence on specific aspects such as academic performance or social integration. The objective was analyze the acute effect of an aerobic physical exercise session on selective attention in a sample of 48 boys and 40 girls (Age, M ± DT = 9.48 ± .505 years). A quasi-experimental study design with a control group and an experimental group was used. Physical exercise involves walking a mile as quickly as possible. Selective attention was measured with the Face Test. The experimental group was divided into two subgroups (minor v. major) according to the time spent in the mile. The results of the differences affected in correct answers (p = .012), inhibitory control (p = .020) and omissions (p = .007) after the intervention. An inverse correlation was detected between the time spent on physical exercise and correct answers (p = .022). The analysis of variance detected higher records in correct answers (p = .047) in the group with less time spent. The results suggest that performing a short duration aerobic exercise session could have positive acute effects on selective attention. Performing physical exercise like the mile in less time is related to better selective attention. A better aerobic capacity could be related to more selective attention.

Antecedentes: la intervención musical se considera una modalidad óptima para mejorar la motivación del ejercicio, el rendimiento del ejercicio y la capacidad de resistencia. El objetivo de este estudio es investigar los efectos agudos de la intervención musical autoseleccionada sobre la frecuencia cardíaca (FC) posterior al ejercicio, la variabilidad de la FC (VFC) y la ansiedad después de una intensidad submáxima del ejercicio en bicicleta. Métodos: Cincuenta y dos adultos sanos (hombres: n = 24, edad: 20.6 ± 2 años; mujeres: n = 28, 21.8 ± 2.1 años) participaron voluntariamente en este estudio. Se utilizó un diseño equilibrado para examinar la intensidad submáxima del ejercicio de ciclismo con ensayos musicales no musicales o autoseleccionados con al menos 48 horas de diferencia. Los participantes primero visitan el laboratorio para determinar la música individual seleccionada por ellos mismos y completar una prueba de ejercicio incremental hasta que la respuesta de FC investigue al 80% de la reserva de frecuencia cardíaca (HRreserve). El 80% HRreserve se utilizó para controlar la intensidad del ejercicio durante un ejercicio de ciclismo estacionario de 10 minutos. Al comienzo del experimento, los participantes realizaron un ejercicio de calentamiento en bicicleta de 5 minutos con ritmo propio. Posteriormente, los participantes descansaron sentados durante 5 minutos y luego realizaron 10 minutos de ejercicio en bicicleta con una intensidad de reserva de HR del 80%. Después del ejercicio de ciclismo, se midió la recuperación de la FC de 5 minutos (HRR) y la HRV de 10 minutos en una posición sentada durante 15 minutos. Se utilizó una escala de masa de ansiedad situacional (STAI-S) inmediatamente después del ejercicio de ciclismo. La intervención musical se aplicó durante 15 minutos después de la recuperación del ejercicio. Resultados: El HR de ejercicio y el HRV posterior al ejercicio no mostraron diferencias significativas entre el ensayo musical autoseleccionado y el ensayo no musical en ambos grupos. En la prueba musical autoseleccionada, la HRR fue significativamente más rápida después de la prueba musical autoseleccionada que la de la prueba no musical en mujeres. Además, las puntuaciones de STAI-S fueron significativamente más bajas en la prueba musical autoseleccionada que en la prueba no musical en ambos grupos. Conclusión: la intervención musical autoseleccionada puede mejorar la HRR en mujeres sanas. Se justifica la implementación de una intervención musical autoseleccionada después de la intensidad submáxima del ejercicio de ciclismo estacionario para reducir la ansiedad posterior al ejercicio en hombres y mujeres.

This study investigated the acute effects of seated and supine knee extension exercise on muscle swelling, torque, and work output. Twelve resistance-trained men performed two isokinetic concentric-only knee-extension training protocols at different hip positions in a counter-balanced order. They completed the knee extension exercise in the seated (hip angle at 85°) and supine (hip angle at 180°) positions. The torque and work output were assessed during each set. Moreover, muscle thickness of the middle and proximal vastus lateralis and rectus femoris were evaluated before and after each protocol and used as an indicator of muscle swelling. Middle rectus femoris and proximal vastus lateralis thickness increased significantly (p=0.01) with no difference between exercise variations. However, the middle vastus lateralis thickness increased (p=0.01) only after the seated knee extension exercise (~7%). Knee extensors’ peak torque and work output were approximately 8% higher (p=0.04) in the seated when compared to the supine hip position. There was a similar decrease in torque and work output throughout both protocols (p=0.98). In conclusion, seated knee extension exercises produced greater torque, work output, and muscle swelling in the vastus lateralis when compared to the supine knee extension exercise.

Introduction. Tartrazine is an azofood additive widely used in the pharmaceu-cal, cosmetic, food, and other industries. Objective. To assess the effects of tartrazineon the attitude to move and to eat, and histological changes in digestive, and renal sys-tem, after an acute treatment on a biological model the snail Helix aspersa. Material and Methods. Snails were exposed orally, and by contact to flour contaminated with this dye for 24 hours. Adult snails were divided into two groups of 20 animals each. The control group fed flour alone. The experimental group was administered orally with flour treated with tartrazine (200mg/g flour). Results. The observation of behaviour revealed inhibitory effects of tartrazine on locomotion, and nutrition of snails. Histolo-gical examination of intestines, hepatopancreas, and kidney of treated animals showed altered tissue structures, with advanced degeneration of digestive tubules, connective tissue, and smooth muscle fibers of the walls surrounding the three organs, in response to tartrazine, compared to controls. Conclusion. This study suggests that acute exposure to tartrazine may lead to disorders in locomotor, and nutritional behavior, in addition to tissue alterations. Therefore, this study on behavior, supported by histological changes in H. Aspersa can be used as potential biomarkers of exposure to other azodyes.

Background: Baseball pitching injuries are increasing at an alarming rate. While weighted ball throwing programs may be effective at increasing pitching velocity, previous research has identified a 24% injury rate and a 3.3° increase in shoulder external rotation (ER) range of motion (ROM) after performing a 6-week program. However, previous research has not investigated, separately, the immediate effects of throwing underloaded and overloaded balls on ROM. The purpose of this study was to examine the acute effects of throwing differently weighted baseballs on shoulder ROM. By analyzing these differences, it may be possible to determine the specific weight range that may lead to the greatest increase in ROM and potential injury risk. Hypothesis: Throwing with weighted balls will result in an increase in shoulder ER ROM. Study Design: Randomized controlled trial. Level of Evidence: Level 2. Methods: A total of 16 male high school baseball pitchers agreed to participate in this study. The participants were (mean ± SD) 17.1 ± 1.0 years of age, 1.81 ± 0.09 m tall, and had a mass of 79.2 ± 11.1 kg. Each participant was tested on 3 different days, 1 week apart, with 3 different conditions in random order: (1) underload throwing, using regulation 5-oz baseballs and 4- and 2-oz balls; (2) overload throwing, using 5-, 6-, and 9-oz balls; and (3) extreme overload throwing, using 5-, 16-, and 32-oz balls. Each testing session began by measuring passive shoulder ROM (external rotation and internal rotation) using standard goniometric measurements. Participants then performed 3 throws with each weighted ball from 3 different positions (kneeling, rocker, and run-and-gun) for a total of 27 throws each test session. ROM measurements were repeated at the end of each test session. The effect of each throwing condition on ROM was compared from pre- to posttraining using a paired t test ( P ≤ 0.05). Results: There was no significant difference in ER after throwing at underloaded weights. The overload condition showed a statistically significant increase of 3.3° in external rotation ( P = 0.05). The extreme overload condition showed a statistically significant increase in ER of 8.4° ( P < 0.001). There were no differences in internal rotation for any group. Conclusion: A significant increase in shoulder ER was observed immediately after throwing overload weighted balls. This effect increased as the weights of the balls increased. Clinical Relevance: Throwing with overload weighted baseballs causes an immediate increase in shoulder ER ROM. It is unknown why these changes occur; however, the results may explain both the increase in velocity and injury rates previously observed from throwing weighted balls. The current study results may be used to develop more scientifically validated weighted ball programs. Heavier balls should be used with caution, and ROM should be monitored during implementation of these programs.

Intense exercise promotes long-term gains in cognitive functions. On the other hand, intense exercise may result in acute effects not clearly determined for cognitive performance. A condition of stochastic intensity ranging from moderate to maximal efforts is part of sports like cycling, in which cognitive integrity is also important for fast decision making and information processing especially during high-speed performances. In this study we investigate the acute effect of cycling at intensities corresponding to 60%, 80% and 95% of the maximal power output (MP) on selective attention, reaction time and short-term memory in amateur trained cyclists. In this cross sectional study 20 male cyclists performed maximal and submaximal cycling tests under different exercise intensities. Cognitive measures were conducted before and after exercise. We found that short duration high intensity cycling (95%) improves selective attention but increases variability in simple reaction time responses, without significant effects on short-term memory. The high intensity exercise improves ability to manage more complex cognitive task especially when the variability in the task does not increase.

Purpose To compare the acute effects of passive movement combined with blood flow restriction (PM + BFR) to passive movement (PM) or blood flow restriction alone (BFR). Methods A total of 20 healthy participants completed: time control (TC), PM, BFR and PM + BFR (one per leg, over 2 days; randomized). For PM, a dynamometer moved the leg through 3 sets of 15 knee extensions/flexions (90° at 45°/second). For BFR, a cuff was inflated to 80% arterial occlusion pressure on the upper leg. Measurements consisted of anterior muscle thickness at 60% and 70% of the upper leg before and after (-0, -5 and -10 min) conditions, ratings of perceived effort and discomfort before conditions and after each set, and of the vastus lateralis during conditions. Data, presented as mean (SD), were compared using Bayesian RMANOVA, except for perceived effort and discomfort, which were compared using a Friedman's test (non-parametric). Results 60% (Δcm before-after-0: TC = 0.04 [0.09], PM = -0.01 [0.15], BFR = 0.00 [0.11], PM + BFR = 0.01 [0.22]) and 70% (Δcm before-after-0: TC = 0.01 [0.09], PM = -0.01 [0.15], BFR = 0.02 [0.11], PM + BFR = -0.03 [0.22]) muscle thickness did not change. Perceived effort was greater than TC following PM (p = .05) and PM + BFR (p = .001). Perceived discomfort was greater following BFR and PM + BFR compared to TC (all p ≤ .002) and PM (all p ≤ .010). Changes in deoxygenation (e.g. channel 1; ΔμM start set 1-end set 3: TC = 0.9 [1.2], PM = -1.2 [1.9], BFR = 10.3 [2.7], PM + BFR = 10.3 [3.0]) were generally greater with BFR and PM + BFR (BFinclusion = 1.210e + 13). Conclusion Acute muscular responses to PM + BFR are not augmented over the effect of BFR alone.

Pareja-Blanco, F, Pereira, LA, Freitas, TT, Alcaraz, PE, Reis, VP, Guerriero, A, Arruda, AFS, Zabaloy, S, De Villarreal, ES, and Loturco, I. Acute effects of progressive sled loading on resisted sprint performance and kinematics. J Strength Cond Res XX(X): 000-000, 2020-We examined the effects of 5 loading conditions (0, 20, 40, 60, and 80% of body-mass [BM]) on resisted sprint performance and kinematics in male rugby players over different distances. Ten players from the Brazilian National Team (20.1 ± 3.3 years; 88.7 ± 18.8 kg; 178.3 ± 6.2 cm) performed 20-m sprints under the 5 loading conditions. Sprint times in 5, 10, and 20 m were recorded. Stride length (SL), and hip, knee, and ankle angles were measured using an eight-sensor motion analysis system. The kinematic parameters were calculated over the different distances. Heavier loads led to significantly greater velocity loss (p < 0.001-0.05). Significant reductions in SL were also observed when comparing 0% BM and all resisted sprints in all assessed distances (p < 0.001-0.05, effect size [ES]: 1.35-4.99). Very heavy (80% BM) sled load provoked significantly greater decreases in SL than the rest of loading conditions (p < 0.01-0.05). Important kinematic alterations were observed for all loading conditions and sprint distances when compared with 0% BM (ES: 0.76-1.79, for hip-angle; 0.20-1.40, for knee-angle; and 0.73-1.88, for ankle-angle). Moreover, 80% BM induced significantly higher hip flexion, lower knee flexion, and higher ankle dorsiflexion than 20% BM condition at 5-10 and 10-20 m distances (p < 0.05). Lighter sled loads (

Merrigan, JJ, Tufano, JJ, Fields, JB, Oliver, JM, and Jones, MT. Rest redistribution does not alter hormone responses in resistance-trained women. J Strength Cond Res 34(7): 1867-1874, 2020-The purpose was to examine acute effects of rest redistribution (RR) on perceptual, metabolic, and hormonal responses during back squats. Twelve resistance-trained women (training age 5 ± 2 years; one repetition maximum [1-RM] per body mass, 1.6 ± 0.2) performed traditional (TS, 4 sets of 10 repetitions with 120 seconds interset rest) and RR sets (4 sets of two 5 repetition clusters with 30-second intraset rest and 90-second interset rest) in counterbalanced order, separated by 72 hours. Both conditions were performed at 70% 1RM with 360 seconds of total rest. Ratings of perceived exertion (RPE) were taken after each set. Blood was sampled at baseline, after each set, and at 5, 15, 30, and 60 minutes, as well as 24 and 48 hours after training. Alpha level was p ≤ 0.05. The RPE progressively increased throughout both conditions (p = 0.002) with a greater overall mean for TS (5.81 ± 0.14) than RR (4.71 ± 0.14; p = 0.003). Lactate increased above baseline and remained elevated through 15 minutes post in both conditions (4.00 ± 0.76; p = 0.001), with greater lactate levels for TS (6.33 ± 0.47) than RR (4.71 ± 0.53; p0.001). Total testosterone was elevated after set 2 (0.125 ± 0.02; p = 0.011), but no other time point, while free testosterone remained unchanged. Growth hormone continually rose from baseline to set 3 and returned to baseline by 60 minutes post (20.58 ± 3.19). Cortisol and creatine kinase did not change over time. No condition × time interactions existed for any hormone (p0.05). Use of rest redistribution resulted in lower perceived effort and lactate responses. Yet, hormone responses during rest redistribution were no different from TS.