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In the title molecule, C26H18N2, the 9H-fluorene unit is almost planar, as the cyclopentadiene ring makes dihedral angles of 1.12 (6) and 1.46 (6)° with the fused benzene rings. The dihedral angle between the two phenyl rings of the diphenylmethylene residue is 61.78 (6)°.

In the title compound, C23H16N2·0.5C6H6, the benzimidazole unit [maximum deviation = 0.0258 (6) Å] and the naphthalene ring system [maximum deviation = 0.0254 (6) Å] are both essentially planar and make a dihedral angle of 61.955 (17)°. The imidazole ring makes dihedral angle of 61.73 (4)° with the phenyl ring. An intramolecular C—H...N hydrogen bond generates an S(6) ring motif. In the crystal, seven weak C—H...π interactions involving the fused ring system, the benzene solvent molecule, the imidazole phenyl rings are observed, leading to a three-dimensional architecture.

In the title molecule, C13H13ClN2OS, the heterocyclic ring adopts a flattened boat conformation with the plane through the four coplanar atoms making a dihedral angle of 85.6 (1)° with the benzene ring, which adopts an axial orientation. The thionyl, acetyl and methyl groups all have equatorial orientations. Intermolecular N—H...O, N—H...S and C—H...S hydrogen bonds are found in the crystal structure. A weak C—H...π interaction involving the benzene ring also occurs.

The asymmetric unit of the title compound, C21H23NO4, contains two crystallographically independent molecules A and B. In both molecules, the piperidine-4-one rings adopt a distorted twist-boat conformation. The formyl group at position 1, the methoxyphenyl ring at position 2 and the methyl group at position 3 are attached equatorially. The methoxy phenyl ring at position 6 has an axial orientation. The dihedral angle between the two benzene rings is 55.27 (8)° in molecule A, and 55.29 (8)° in molecule B. In the crystal, the molecules are linked by weak C—H...O intermolecular hydrogen-bond interactions. In addition, weak C—H...π intermolecular interactions involving the benzene rings at positions 6 and 2 of molecule B are also found in the crystal structure.

In the title compound, C17H13N, the dihedral angle between the two phenyl rings is 17.6 (1)°. An intermolecular C—H...N hydrogen bond is found in the crystal structure, also a C—H...π interaction involving the phenyl ring at position 5.

In the title compound, C(15)H(13)N(3)O·H(2)O, the dihedral angle between the pyridine and phenyl rings is 35.45 (7)°. Inter-molecular O-H⋯O, O-H⋯N, N-H⋯O and C-H⋯O hydrogen bonds are found in the crystal structure. In addition, C-H⋯π inter-actions involving the pyridine and phenyl rings are also found.

In the title molecule, C18H19NOS2·H2O, the piperidine ring adopts an envelope conformation with the methyl substituent in an equatorial position. Each of the olefinic double bonds has an E configuration. The dihedral angle between the two thiophene rings is 6.04 (14)°. The water molecule forms two donor interactions, one with the carbonyl O atom and the other to the hetero N atom. The centrosymmetric {C18H19NOS2·H2O}2 pairs thus formed are linked into a supramolecular chain via C—H...Owater contacts.

In the title molecule, C22H16N2, the pyrazine ring deviates very slightly from planarity [maximum deviation 0.044 (3) Å], tending towards a twist-boat conformation. The phenyl ring at position 3 makes dihedral angles of 64.0 (2) and 45.8 (2)°, respectively, with the phenyl rings at positions 2 and 5. The dihedral angle between the phenyl rings at positions 2 and 5 is 49.7 (2)°. A C—H...π interaction is found in the crystal structure, but no classical hydrogen bonds form.

Dimmock, J. R., Padmanilayam, M. P., Puthucode, R. N., Nazarali, A. J., Motaganahalli, N. L., Zello, G. A., Quail, J. W., Oloo, E. O., Kraatz, H. B., Prisciak, J. S., Allen, T. M., Santos, C. L., Balsarini, J., Clercq, E. D. & Manavathu, E. K. (2001). J. Med. Chem. 44, 586–593. Farrugia, L. J. (1997). J. Appl. Cryst. 30, 565. Flack, H. D. (1983). Acta Cryst. A39, 876–881. Gayathri, P., Thiruvalluvar, A., Manimekalai, A., Sivakumar, S. & Butcher, R. J. (2008). Acta Cryst. E64, o1973. Noller, C. & Baliah, V. (1948). J. Am. Chem. Soc. 70, 3853–3855. Oxford Diffraction (2008). CrysAlis CCD and CrysAlis RED. Oxford Diffraction Ltd, Abingdon, Oxfordshire, England. Perumal, R. V., Agiraj, M. & Shanmugapandiyan, P. (2001). Indian Drugs, 38, 156–159. Ponnuswamy, S., Venkatraj, M., Jeyaraman, R., Suresh Kumar, M., Kumaran, D. & Ponnuswamy, M. N. (2002). Indian J. Chem. Sect B, 41, 614–627. Sheldrick, G. M. (2008). Acta Cryst. A64, 112–122. Spek, A. L. (2003). J. Appl. Cryst. 36, 7–13. organic compounds

In the title molecule, C13H13ClN2O2, the heterocyclic ring adopts a flattened boat conformation with the plane through the four coplanar atoms making a dihedral angle of 89.16 (5)° with the benzene ring, which adopts an axial orientation. The carbonyl, acetyl and methyl groups each have an equatorial orientation. In the crystal structure, intermolecular N—H...O hydrogen bonds lead to a tape motif. The H atoms of the methyl group at position 6 are disordered over two positions of opposite orientation.

In the title molecule, C14H16N2O3, the heterocyclic ring adopts a flattened boat conformation, and the plane through its four coplanar atoms makes a dihedral angle of 89.65 (7)° with the benzene ring. The non-H atoms of the carbonyl, acetyl and methyl groups are nearly coplanar with the attached heterocyclic ring. Intermolecular N—H...O and C—H...O hydrogen bonds are present in the crystal structure.

The asymmetric unit of the title compound, C21H25NO3, contains two crystallographically independent molecules (A and B). In both molecules, the piperidine ring adopts a chair conformation, with the methoxyphenyl rings attached equatorially. The dihedral angle between the two benzene rings in molecule A is 73.79 (8)°; the corresponding value in molecule B is 77.71 (8)°. The molecules are linked by N—H...O hydrogen bonds. In addition, C—H...π interactions are also found in the crystal structure.

In the title molecule, C20H20Cl2N2O2, the piperidine ring adopts a chair conformation and the nitroso group at position 1 has a bisectional orientation. The two benzene rings and the isopropyl group attached to the piperidine ring in positions 2, 6 and 3, respectively, have axial orientations. The dihedral angle between the two benzene rings is 21.56 (13)°. One of the Cl atoms is disordered over two positions in a 0.281 (5):0.719 (5) ratio. In the crystal structure, molecules are linked by C—H...O hydrogen bonds and a short C—H...O contact occurs within the molecule.

The carbazole unit of the title molecule, C12H10ClNO, is not planar. The dihedral angle between the benzene and pyrrole rings is 1.35 (10)°. The cyclohexene ring adopts an envelope conformation. In the crystal structure, intermolecular N—H...O hydrogen bonds form centrosymmetric dimers.

In the title molecule, C16H14OS, the dihedral angle between the phenyl and benzene rings is 3.81 (15)°. The H atoms of the central enone group are trans. The propenone unit makes dihedral angles of 11.73 (18) and 11.62 (17)° with the benzene and phenyl rings, respectively. The crystal structure is stabilized by weak C—H...O and C—H...π interactions.

In the title molecule, C12H15NO2, the oxazole ring adopts an envelope conformation. Overall, the molecule is approximately planar, the dihedral angle between the mean plane through all but the methylene C atom of the five-membered ring and the aromatic ring being 8.6 (1)°. A weak C—H...O interaction contributes to the stabilization of the crystal structure.

In the title molecule, C15H17NO3, the piperidine ring adopts a chair conformation. The dihedral angle between the two furyl rings is 72.4 (1)°. The ethyl group and the furyl rings have equatorial orientations. Molecules are linked by N—H...O hydrogen bonds.

The title compound, C22H20N2, crystallizes with two independent molecules (A and B) in the asymmetric unit. The benzimidazole units are almost planar [maximum deviations = 0.0161 (8) Å for A and 0.0276 (8) Å for B]. The dihedral angles between the benzimidazole unit and the benzene rings of the 4-methylbenzyl and 4-methylphenyl groups are 76.64 (3) and 46.87 (4)°, respectively, in molecule A. The corresponding values in molecule B are 86.31 (2) and 39.14 (4)°. The dihedral angles between the planes of the two benzene rings are 73.73 (3) and 80.69 (4)° in molecules A and B, respectively. Pairs of weak intermolecular C—H...N hydrogen bonds link B molecules, forming centrosymmetric dimers with R22(8) ring motifs. There are no significant corresponding interactions involving the A molecules.

The title molecule consists of a piperidin-4-one ring fused to a cyclohexane moiety. The piperidine ring adopts a twisted conformation and the cyclohexane ring adopts a chair conformation. The crystal structure determination confirms the trans fusion of the two rings.

The crystal structure of the α form of bis(N,N-diethyldithiocarbamato-S,S')nickel(II), [Ni(C 5 H 10 NS 2 ) 2 ], has been redetermined at 290 K by single-crystal X-ray methods. The Ni atom assumes a four-coordinate square-planar geometry with two isobidentate dithiocarbamate groups. The results confirm those of a previous study [Bonamico, Dessy, Mariani, Vaciago & Zambonelli (1965). Acta Cryst. 19, 619-627] but are more precise

A molecule of the title compound, C 14 H 15 NO, consists of an isoxazole ring fused to norbornane. The conformation of the five-membered isoxazole ring is nearly planar and its fusion onto the norbornane moiety is exo

The diazepine ring adopts a slightly distorted chair conformation. The phenyl substituents adopt equatorial orientations. The unsymmetrical distortion arises from the torsional strains between the phenyl and isopropyl groups. The compound exists as a dimer exhibiting intermolecular N-H...O hydrogen bonding

In the title mol-ecule, C(14)H(14)ClNO, the cyclo-hexane ring adopts a chair conformation. The cyano group and the methyl group have axial and equatorial orientations, respectively. The benzene ring has an equatorial orientation. A C-H⋯π inter-action involving the benzene ring is found in the crystal structure.

In the title compound, C13H13NO, the dihedral angle between the benzene ring and the fused pyrrole ring is 0.96 (7)°. The cyclohexenone ring adopts an envelope conformation. Intermolecular N—H...O hydrogen bonds form R22(10) ring motifs in the crystal structure. Weak C—H...π interactions involving the benzene ring also occur.

In the title molecule, C13H13NO, the dihedral angle between the benzene ring and the fused pyrrole ring is 2.03 (5)°. The methyl group at the 3-position has an equatorial orientation. The cyclohexene ring adopts an envelope conformation. Three C atoms of the cyclohexene ring, with their attached H atoms, and all atoms of the methyl group are disordered over two positions, the site-occupancy factors being 0.883 (2) and 0.117 (2). In the crystal structure, molecules are stabilized by intermolecular N—H...O hydrogen bonds. A C—H...π interaction, involving the benzene ring, is also found.

In the title mol-ecule, C(13)H(13)ClN(2)OS, the heterocyclic ring adopts a flattened boat conformation, and the plane through the four coplanar atoms makes a dihedral angle of 87.92 (10)° with the benzene ring. The thione, acetyl and methyl groups have equatorial orientations with respect to the attached heterocyclic ring. The chloro-phenyl group has an axial orientation. Inter-molecular N-H⋯O, N-H⋯S and C-H⋯O hydrogen bonds are found in the crystal structure.

In the title molecule, C16H13FOS, the dihedral angle between the two benzene rings is 8.68 (6)°. The H atoms of the central enone group are trans and one H atom is involved in a close intramolecular C—H...O contact. The crystal structure is stabilized by weak C—H...π interactions.

In the title mol­ecule, C15H11F3N4O, the quinoline unit is nearly planar. The dihedral angle between the pyridine ring and the fused benzene ring is 2.45 (6)°. The triazole ring makes dihedral angles of 63.7 (1) and 64.7 (1)° with the pyridine and benzene rings, respectively. The ethanone group is coplanar with the attached triazole ring, except for the methyl H atoms. C—H⋯O, C—H⋯N and C—H⋯F hydrogen bonds are found in the crystal structure.

The heterofused carbazole unit of the title compound, C15H13N3O2, is not planar. The planar pyrazole ring forms dihedral angles of 2.52 (8)°, 3.18 (7)° and 2.22 (6)° with the pyrrole ring, the benzene ring and the attached carboxyl­ate group respectively. The cyclo­hexene ring adopts a half-chair conformation. In the crystal structure, the mol­ecules are stabilized by inter­molecular N—H⋯O and O—H⋯N hydrogen bonds.

The carbazole unit of the title mol­ecule, C14H11NO2, is planar. The hydr­oxy group at position 1, carbaldehyde group at position 2, and methyl group at position 3 (with the exception of two H atoms) are coplanar with the attached benzene ring. The dihedral angle between the two benzene rings is 3.57 (8)°. The pyrrole ring makes dihedral angles of 1.53 (9) and 2.06 (9)° with the unsubstituted and substituted benzene rings, respectively. The structure is stabilized by inter- and intra­molecular N—H⋯O and O—H⋯O hydrogen bonds.

In the title mol­ecule, C14H15NO, the cyclo­hexane ring adopts a chair conformation. The cyano group and the methyl group have axial and equatorial orientations, respectively. The phenyl ring has an equatorial orientation.

In the title molecule, C17H19NO, the piperidine ring adopts a chair conformation. The acetyl group in the 1-position and ethyl group in the 3-position each have an equatorial orientation. The furyl rings at positions 2 and 6 have axial orientations.