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In recent years, with the development of society and economy, credit cards have been popularized due to their low interest rate and easy payment. However, with the advent of the epidemic era, the unemployment rate has increased, making the probability of credit card defaults rising. The prediction of credit card default helps banks and financial institutions balance the risk and economic interests, contributes to the stable and healthy development of the financial industry, and plays an important role in bank credit control. Therefore, this paper addresses the credit card default prediction problem by using Random forest, Decision tree, LightGBM, XGBoost, Logistic regression, and Adaboost models to make predictions and compare the results. The outcomes demonstrate that LightGBM algorithm has the most outstanding prediction score, and its AUC value can reach 0.78 and recall rate reaches 0.95.

Minority shareholders are important stakeholders of the company, which could influence the corporate innovation to a certain extent. This paper studies the impact of online voting by minority shareholders on corporate innovation, which could enrich the research and expand the theoretical mechanism of the voting role of small and medium shareholders. Taking the 2008-2020 years of China's A-share listed companies as a sample and using the relative proportion of minority shareholders to attend the general meeting to measure the online voting of minority shareholders and the rate of R&D investment to operating income to measure corporate innovation, we found that:(1)the degree of online voting participation of small and medium shareholders is significantly negatively associated to corporate innovation;(2) the degree of online voting participation of minority shareholders reduces the voice of the management , weakening the management's constraint on the interests of large shareholders (3) With the improvement of the shareholding balance, the impact of online voting participation of minority shareholders on enterprise innovation decreases significantly; the more the stake of the largest shareholder , the stronger the inhibitory effect of minority shareholders' online voting participation on enterprise innovation is.

To evaluate the associations of baseline and long-term trajectories of lifestyle with incident ischemic heart diseases (IHD).29,164 participants in the UK Biobank who had at least one follow-up assessment and were free of IHD at the last follow-up assessment were included. We constructed a weighted unhealthy lifestyle score though summing five lifestyle factors (smoking, physical activity, diet, BMI, and sleep duration). Lifestyle assessed at baseline (2006-2009), the first follow-up assessment (2012-2013) and the second follow-up assessment (since 2014) were used to derive the trajectories of each individual. The joint categories were created through cross-classifying three baseline lifestyle categories (ideal, intermediate and poor) by three lifestyle trajectory categories (improve, maintain and decline).During a median follow-up period of 4.2 years, 868 IHD events were recorded. The hazard ratio (HR) of incident IHD associated with per unit increase in unhealthy lifestyle trajectory was 1.08 (95% confidence interval (CI): 0.99-1.17). Subgroup analyses indicated such association was stronger among individuals with hypertension (HR: 1.13, 95%CI: 1.03-1.24), diabetes (HR: 1.23, 95%CI: 0.96-1.58) or hyperlipidemia (HR: 1.09, 95%CI: 0.97-1.22). Compared with participants consistently adhering to an ideal lifestyle (ideal-maintain), the HRs of incident IHD were: 1.30 (1.07-1.58) for intermediate-maintain, 1.52 (1.23-1.88) for poor-maintain, 1.25 (0.93-1.68) for intermedia-improve, 1.48 (1.17-1.88) for poor-improve, 1.46 (1.08-1.99) for intermedia-decline and 1.77 (1.21-2.59) for poor-decline.A declined lifestyle trajectory increased the risk of incident IHD, irrespective of baseline lifestyle levels. Individuals with hypertension, diabetes or hyperlipidemia were more predisposed to the influence of lifestyle change.It is known that unhealthy lifestyle at baseline was associated with increased risk of cardiovascular diseases (CVD), but the risk attributed to the lifestyle changes (or trajectories) over the long term has not been well quantified. Meanwhile, the effects of lifestyle, either in baseline level or trajectories, on different CVD subtypes such as ischemic heart diseases (IHD) and stroke varied. Thus, this study used the data from UK Biobank to construct a weighted unhealthy lifestyle score; then to evaluate the prospective associations of baseline and long-term trajectories of the unhealthy lifestyle score with the risk of incident IHD. A total of 352,251 and 29,164 participants were included in the unhealthy lifestyle construction and lifestyle trajectory analysis, respectively. We found a poorer lifestyle at baseline was significantly associated with an increased risk of incident IHD in a linear dose-response fashion. Besides, a declined lifestyle trajectory was associated with an increased risk of incident IHD, irrespective of baseline lifestyle levels, and such association was stronger among individuals with hypertension, diabetes or hyperlipidemia. Compared with the maintainers, risks of incident IHD attenuated when individuals improved their lifestyle and strengthened when declined their lifestyle. 1. A declined lifestyle trajectory increased the risk of incident IHD, irrespective of baseline lifestyle levels. Such association was stronger among participants with hypertension, diabetes or hyperlipidemia. 2. Compared with the maintainers of lifestyle, risks of incident IHD attenuated when individuals improved their lifestyle and strengthened when declined their lifestyle.

Luminescence intensity ratio and single-band ratiometric thermometries have been achieved in one material.

The scientific planning of urban future space layout improves the quality of the regional economy for the city's future development and has important guiding significance. Taking Shanghai as an example, this paper first quantifies the regional industrial cluster and regional economy, then constructs the artificial neural network-radial basis function (ANN-RBF) algorithm and sets the algorithm test index. Based on data collection, RBF is used for contribution analysis to explore the impact of regional industrial clusters on regional economic indicators in Shanghai, China. The results show that the ratio of foreign investment (11.4%), the percentage of the tertiary industry's added value to the secondary industry's (10%) to the regional economy of Shanghai, China is more prominent than the other indicators. The scientific and technological achievements, energy consumption per unit of GDP, and electricity consumption accounted relatively small. This paper's significance is conducive to analyzing the correlation between regional economic and industrial cluster indicators in Shanghai, China.

High-density semiconducting aligned carbon nanotube (A-CNT) arrays have been demonstrated with wafer-scale preparation of materials and have shown high performance in P-type field-effect transistors (FETs) and great potential for applications in future digital integrated circuits (ICs). However, high-performance N-type FETs (N-FETs) have not yet been implemented with A-CNTs, making development of complementary metal-oxide-semiconductor (CMOS) technology, a necessary component for modern digital ICs, impossible. In this work, we reveal the mechanism hindering the realization of A-CNT N-FETs contacted by low-work-function metals and develop corresponding solutions to promote the performance of N-FETs to that of P-type FETs (P-FETs). The fabricated scandium (Sc)-contacted A-CNT N-FET with a 100 nm gate length exhibits an on-state current (

In order to provide a basis for the prevention of RA, this systematic review and meta-analysis evaluated the association between passive smoking and the risk of developing RA. We searched electronic databases, including PubMed, Cochrane Central Register of Controlled Trials, Web of Science, and Embase, for published literature from the establishment to March 2022. Then we included subject-related cohort studies and case-control studies, and two researchers independently screened and extracted relevant data. Finally, we performed a meta-analysis, cumulative meta-analysis, and dose-response meta-analysis using the Stata software and evaluated the included literature for the level of evidence. This meta-analysis included three case-control and three cohort studies. There was only a small amount of statistical heterogeneity among the studies (I

Establishing an effective signal amplification strategy is the key to achieving sensitive detection of analytes by electrochemical immunoassay. In this work, a novel sandwich-type electrochemical immunosensor with dual-signal amplification was successfully constructed using PtPd/Cu-TCPP(Fe) as the sensing platform and mesoporous silicon dioxide as the signal amplifier. Firstly, two-dimensional wrinkled Cu-TCPP(Fe) nanomaterials loaded with PtPd nanoparticles have strong affinity for the immobilization of capture antibodies and can generate excellent electrochemical signals. Meanwhile, the mesoporous silicon dioxide with large steric hindrance was used as signal label to further improve the sensitivity of the immunosensor by increasing the difference of the current response signal. Under optimal experimental conditions, the electrochemical immunosensor exhibited a wide linear detection range from 0.1 pg/mL to 1.0 μg/mL, with a detection limit as low as 0.166 fg/mL. The experimental results showed that the constructed immunosensor has a great application prospect in clinical biomarker detection.

To evaluate the analgesic effect of pectoral nerve block in implant-based mammoplasty.EMbase, PubMed, Web of science, MEDLINE, CNKI, Wanfang Database, VIP and other databases were searched from establishment to February 2022 by computer to collect randomized controlled trials which applied pectoral nerve block in implant-based mammoplasty, and meta-analysis was conducted after data extraction and quality evaluation of the literature meeting the inclusion criteria.A total of 336 patients in seven RCT studies were included in this study. Pectoral nerve block has a significant effect on postoperative analgesia in patients with implant-based mammoplasty with 1h VAS score significantly reduced in the resting state (MD=-1.85, 95%CI: -2.64~-1.07, P0.00001); VAS score was significantly decreased 4-6 hours after operation (MD=-1.51, 95%CI: -2.47~-0.55, P=0.002); postoperative opioid consumption was reduced (SMD=-1.37, 95%CI: -2.51~-0.24, P=0.02) in PECS block group; and the incidence of postoperative nausea and vomiting in the PECS block group was significantly lower (RR: 0.30, 95 %CI: 0.19-0.38, P0.00001).The application of PECS block in submuscular implant-based mammoplasty can effectively reduce the degree of acute postoperative pain, opioid consumption and the incidence of postoperative nausea and vomiting, indicating its broad prospects in clinical application.This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .