779 results on '"Zhang, Guanxin"'
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152. Fluorogenic Enhancement of an in Vitro-Selected Peptide Ligand by Replacement of a Fluorescent Group
153. Tuning the Solid State Emission of the Carbazole and Cyano-Substituted Tetraphenylethylene by Co-Crystallization with Solvents
154. Bio‐/Chemosensors and Imaging with Aggregation‐Induced Emission Luminogens
155. Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression
156. Self-Assembled Nanostructures Based on Activatable Red Fluorescent Dye for Site-Specific Protein Probing and Conformational Transition Detection
157. Remarkable enhancement of charge carrier mobility of conjugated polymer field-effect transistors upon incorporating an ionic additive
158. Essential Role of Pituitary Tumor Transforming Gene 1 (PTTG1) in Vascular Endothelial Cell Activation and Remodeling
159. N‐myc downstream regulated gene‐1 promotes vascular inflammation through activating both NF‐κB and c‐Jun/AP‐1 pathways in endothelial cells
160. Orphan Nuclear Receptors Nur77 and Nor1 Are Novel Regulators of Thrombotic Function in Vascular Endothelial Cells
161. Nur77 Inhibits Isoproterenol‐Induced Cardiac Fibrosis through Upregulation of Relaxin‐3
162. Characterizing the Adsorption of Poly(vinyl alcohol) on Colloidal Silica with Aggregation-Induced Emission Fluorophore
163. ChemInform Abstract: Molecular Materials That Can Both Emit Light and Conduct Charges: Strategies and Perspectives
164. An AIE based tetraphenylethylene derivative for highly selective and light-up sensing of fluoride ions in aqueous solution and in living cells
165. The adjustment of bandgap and coplanarity of diketopyrrolopyrrole-based copolymers through fine-tuning of the conjugated backbones and applications in thin film field effect transistors
166. Conjugated donor–acceptor terpolymers entailing the Pechmann dye and dithienyl-diketopyrrolopyrrole as co-electron acceptors: tuning HOMO/LUMO energies and photovoltaic performances
167. New π-conjugated polymers as acceptors designed for all polymer solar cells based on imide/amide-derivatives
168. A New Fluorometric Turn-on Assay for Carboxylesterase and Inhibitor Screening Based on Aggregation Induced Emission Behavior of Tetraphenylethylene Molecules
169. Conjugated terpolymers synthesized by incorporating anthracene units into the backbones of the diketopyrrolopyrrole-based polymers as electron donors for photovoltaic cells
170. Emissive nanoparticles from pyridinium-substituted tetraphenylethylene salts: imaging and selective cytotoxicity towards cancer cells in vitro and in vivo by varying counter anions
171. Significant Improvement of Semiconducting Performance of the Diketopyrrolopyrrole–Quaterthiophene Conjugated Polymer through Side-Chain Engineering via Hydrogen-Bonding
172. Organic nanoparticles formed by aggregation-induced fluorescent molecules for detection of hydrogen sulfide in living cells
173. Ultrasensitive detection of aliphatic nitro-organics based on “turn-on” fluorescent sensor array
174. Molecular Materials That Can Both Emit Light and Conduct Charges: Strategies and Perspectives
175. Highly Sensitive Thin-Film Field-Effect Transistor Sensor for Ammonia with the DPP-Bithiophene Conjugated Polymer Entailing Thermally Cleavable tert-Butoxy Groups in the Side Chains
176. Targeted and imaging-guided <italic>in vivo</italic> photodynamic therapy for tumors using dual-function, aggregation-induced emission nanoparticles.
- Abstract
Imaging-guided photodynamic therapy (PDT) has been regarded as a promising strategy for precise cancer treatment. Because of their excellent modifiability and drug-loading capacity, nanoparticles have played an important role in PDT. Nonetheless, when traditional photosensitizers are made into nanoparticles, both their fluorescence and reactive oxygen species generation efficacy decrease due to a phenomenon known as aggregation-caused quenching. Fortunately, in recent years, several kinds of organic dyes with “abnormal” properties (termed aggregation-induced emission, AIE) were developed. With enhanced fluorescence emission in the nanoaggregation state, the traditional obstacles mentioned above may be overcome by AIE luminogens. Herein, we provide a better combination of photosensitizers and nanoparticles, namely, dual-function AIE nanoparticles capable of producing reactive oxygen species, to implement targeted and imaging-guided
in vivo PDT. Good contrast ofin vivo imaging and obvious therapeutic efficacy were observed at a low dose of AIE nanoparticles and low irradiance of light, thus resulting in negligible side effects. Our work shows that AIE nanoparticles may play a promising role in imaging-guided clinical PDT for cancer in the near future.[ABSTRACT FROM AUTHOR]
177. A highly selective fluorescence turn-on detection of ClO− with 1-methyl-1,2-dihydropyridine-2-thione unit modified tetraphenylethylene.
178. Three-State Single-Molecule Naphthalenediimide Switch: Integration of a Pendant Redox Unit for Conductance Tuning
179. Tuning the Semiconducting Behaviors of New Alternating Dithienyldiketopyrrolopyrrole–Azulene Conjugated Polymers by Varying the Linking Positions of Azulene
180. Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation
181. A fluorescent turn-on low dose detection of gamma-radiation based on aggregation-induced emission
182. Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing
183. A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria
184. New conjugated molecules with four DPP (diketopyrrolopyrrole) moieties linked by [2,2]paracyclophane as electron acceptors for organic photovoltaic cells
185. Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics
186. Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells
187. Manipulation of the Aggregation and Deaggregation of Tetraphenylethylene and Silole Fluorophores by Amphiphiles: Emission Modulation and Sensing Applications
188. Highly Solid‐State Emissive Pyridinium‐Substituted Tetraphenylethylene Salts: Emission Color‐Tuning with Counter Anions and Application for Optical Waveguides
189. Identification of Bacteria in Water by a Fluorescent Array
190. New dithienyl-diketopyrrolopyrrole-based conjugated molecules entailing electron withdrawing moieties for organic ambipolar semiconductors and photovoltaic materials
191. Tetrathiafulvalene-based switchable architectures
192. A New Tetraphenylethylene-Derived Fluorescent Probe for Nitroreductase Detection and Hypoxic-Tumor-Cell Imaging.
193. A Tetrathiafulvalene-Based Electroactive Covalent Organic Framework
194. Arylacetylene-Substituted Naphthalene Diimides with Dual Functions: Optical Waveguides and n-Type Semiconductors
195. π-Extented Conjugated Polymers Entailing Pechmann Dye Moieties for Solution-Processed Ambipolar Organic Semiconductors
196. Targeted Bioimaging and Photodynamic Therapy of Cancer Cells with an Activatable Red Fluorescent Bioprobe
197. Effects of Sildenafil on Prognosis in Patients with Pulmonary Hypertension After Left-sided Valvular Surgery
198. Donor-Acceptor Molecules: A Cruciform Electron Donor-Acceptor Semiconductor with Solid-State Red Emission: 1D/2D Optical Waveguides and Highly Sensitive/Selective Detection of H2 S Gas (Adv. Funct. Mater. 27/2014)
199. Vibrationally Resolved Photoelectron Spectroscopy of the Model GFP Chromophore Anion Revealing the Photoexcited S1 State Being Both Vertically and Adiabatically Bound against the Photodetached D0 Continuum
200. New Conjugated Molecules with Two and Three Dithienyldiketopyrrolopyrrole (DPP) Moieties Substituted atmetaPositions of Benzene toward p- and n-Type Organic Photovoltaic Materials
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