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151. Intra-hospital transport of critically ill patients with rapid response team and risk factors for cardiopulmonary arrest: A retrospective cohort study

Author

Min, Hyun Ju, primary, Kim, Hyung-Jun, additional, Lee, Dong Seon, additional, Choi, Yun Young, additional, Yoon, Miae, additional, Lee, Dayoon, additional, Cho, Jun Yeun, additional, Park, Jong Sun, additional, Cho, Young-Jae, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, and Lee, Yeon Joo, additional

Published
2019
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152. Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit

Author

Song, Jin Hwa, primary, Kim, Sooyeon, additional, Lee, Hyun Woo, additional, Lee, Yeon Joo, additional, Kim, Mi-jung, additional, Park, Jong Sun, additional, Kim, Yu Jung, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Jong Seok, additional, Lee, Choon-Taek, additional, and Cho, Young-Jae, additional

Published
2019
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153. The Ability of Different Scoring Systems to Predict Mortality in Chronic Obstructive Pulmonary Disease Patients: A Prospective Cohort Study

Author

Kim, Joohae, primary, Lee, Chang-Hoon, additional, Hwang, Seung-Sik, additional, Kim, Deog-Kyeom, additional, Yoon, Ho Il, additional, Lee, Sang Haak, additional, Kim, Ki Uk, additional, Kim, Eun Kyung, additional, Kim, Tae-Hyung, additional, Lee, Ji-Hyun, additional, Oh, Yeon-Mok, additional, and Lee, Sang-Do, additional

Published
2019
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160. Reviews and syntheses : Ocean iron fertilization experiments – past, present, and future looking to a future Korean Iron Fertilization Experiment in the Southern Ocean (KIFES) project

Author

Yoon, Joo-Eun, Yoo, Kyu-Cheul, Macdonald, Alison M., Yoon, Ho-Il, Park, Ki-Tae, Yang, Eun Jin, Kim, Hyun-Cheol, Lee, Jae Il, Lee, Min Kyung, Jung, Jinyoung, Park, Jisoo, Lee, Jiyoung, Kim, Soyeon, Kim, Seong-Su, Kim, Kitae, Kim, Il-Nam, Yoon, Joo-Eun, Yoo, Kyu-Cheul, Macdonald, Alison M., Yoon, Ho-Il, Park, Ki-Tae, Yang, Eun Jin, Kim, Hyun-Cheol, Lee, Jae Il, Lee, Min Kyung, Jung, Jinyoung, Park, Jisoo, Lee, Jiyoung, Kim, Soyeon, Kim, Seong-Su, Kim, Kitae, and Kim, Il-Nam

Abstract

© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Biogeosciences 15 (2018): 5847-5889, doi:10.5194/bg-15-5847-2018., Since the start of the industrial revolution, human activities have caused a rapid increase in atmospheric carbon dioxide (CO2) concentrations, which have, in turn, had an impact on climate leading to global warming and ocean acidification. Various approaches have been proposed to reduce atmospheric CO2. The Martin (or iron) hypothesis suggests that ocean iron fertilization (OIF) could be an effective method for stimulating oceanic carbon sequestration through the biological pump in iron-limited, high-nutrient, low-chlorophyll (HNLC) regions. To test the Martin hypothesis, 13 artificial OIF (aOIF) experiments have been performed since 1990 in HNLC regions. These aOIF field experiments have demonstrated that primary production (PP) can be significantly enhanced by the artificial addition of iron. However, except in the Southern Ocean (SO) European Iron Fertilization Experiment (EIFEX), no significant change in the effectiveness of aOIF (i.e., the amount of iron-induced carbon export flux below the winter mixed layer depth, MLD) has been detected. These results, including possible side effects, have been debated amongst those who support and oppose aOIF experimentation, and many questions concerning the effectiveness of scientific aOIF, environmental side effects, and international aOIF law frameworks remain. In the context of increasing global and political concerns associated with climate change, it is valuable to examine the validity and usefulness of the aOIF experiments. Furthermore, it is logical to carry out such experiments because they allow one to study how plankton-based ecosystems work by providing insight into mechanisms operating in real time and under in situ conditions. To maximize the effectiveness of aOIF experiments under international aOIF regulations in the future, we therefore suggest a design that incorporates several components. (1) Experiments conducted in the center of an eddy structure when grazing pressure is low and silicate levels are hig, This research was a part of the project titled the Korean Iron Fertilization Experiment in the Southern Ocean (KOPRI, PM 16060) funded by the Ministry of Oceans and Fisheries, Korea. This work was partly supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (no. 2015R1C1A1A01052051); the Korea-Arctic Ocean Observing System project (K-AOOS) (KOPRI, 20160245) funded by the MOF, Korea; and the KOPRI project (PE18200). Alison M. Macdonald was supported by NOAA grant no. NA11OAR4310063 and internal WHOI funding.

Published
2018

161. Reassessing the post-Last Glacial Maximum retreat history from the Southwest Ross Sea

Author

McKay, Robert, Lee, Jea Il, Golledge, Nicholas R., Dunbar, Gavin, Kuhn, Gerhard, Kim, Hyoung Jun, Levy, Richard H., Hong, Jong Kuk, Naish, Tim, Yoon, Ho Il, and Yoo, Kyu-Cheul

Abstract

Constraining the timing of the retreat of the Last Glacial Maximum (LGM) Antarctic Ice Sheet in the Ross Sea provides insights into the processes controlling marine-based ice sheet retreat. The over-deepened Ross Sea continental shelf is an ideal configuration for marine ice-sheet instability, and this region was thought to be one of the largest Antarctic contributors to post-LGM sea level rise. However, the chronology and pattern of retreat of the LGM ice sheet in the Ross Sea is largely constrained by coastal records along the Transantarctic Mountain front in the Western Ross Sea. Although these offer more reliable dating techniques than marine sediment cores, they may be influenced by local glaciers derived from East Antarctic outlet glaciers. Consequently, these coastal records may be ambiguous in the broader context of retreat in the central regions of the Ross Sea. However, previous studies have inferred that records in this region retreated in a north to south pattern, and was fed by ice sourced from the central Ross Sea – with the implication that broader ice sheet retreat in the central Ross Sea occurred as late as the mid Holocene. We present two lines of evidence that counter this established interpretation of the pattern of retreat in the Ross Sea: 1) a sedimentary facies succession and foraminifera-based radiocarbon chronology from within the Ross Sea embayment that indicates glacial retreat and open marine conditions to the east of Ross Island was already in place before 8.6 cal ka BP, at least 1 kyr earlier than indicated by terrestrial records in McMurdo Sound; and 2) a new multibeam swath bathymetry data that identifies well-preserved glacial features indicating thick (>700m) marine-based ice derived from the East Antarctic Ice Sheet (EAIS) coastal outlet glaciers dominated the ice sheet input into the southwestern Ross Sea during the last phases of glaciation – and thus may have acted independent of any ice in the central Ross Sea embayment. Comparing these data to new modelling experiments, we hypothesize that marine-based ice sheet retreat was triggered by oceanic forcings along most of the Pacific Ocean coastline of Antarctica, but continued early Holocene retreat into the inner shelf region of the Ross Sea occurred primarily as a consequence of marine ice sheet instability. Keywords: Ross Sea, deglaciation, Last Glacial Maximum, Holocene

Published
2017

163. Simultaneous reduction of flow and fraction of inspired oxygen (FiO2) versus reduction of flow first or FiO2 first in patients ready to be weaned from high-flow nasal cannula oxygen therapy: study protocol for a randomized controlled trial (SLOWH trial).

Author

Kim, Min Chul, Lee, Yeon Joo, Park, Jong Sun, Cho, Young-Jae, Yoon, Ho Il, Lee, Choon-Taek, Lee, Jae Ho, and Kim, Eun Sun

Subjects
NASAL cannula, OXYGEN therapy, RANDOMIZED controlled trials, HOSPITAL mortality
Abstract

Background: High-flow nasal cannula (HFNC) oxygen therapy has been widely used in critically ill patients. Despite the effectiveness of HFNC as a treatment, optimal methods to withdraw HFNC after recovery from preexisting conditions have not been investigated to date. In this study, we will evaluate the safety and efficacy of simultaneous reduction of flow and fraction of inspired oxygen (FiO2) compared with sequential reduction of either flow first or FiO2 reduction first in patients with HFNC.Methods/design: This is a prospective, investigator-initiated, randomized controlled trial with three experimental intervention groups. A total of 100 adult patients receiving HFNC and satisfying weaning criteria will be enrolled and randomly assigned to one of the following groups: flow reduction (FR) first, FiO2 reduction (OR) first, or simultaneous reduction (SR). In the FR group, flow will be reduced first by 10 L/min/h. When it reaches 20 L/min, FiO2 will then be reduced by 0.1 /h until it reaches 0.3. In the OR group, the FiO2 will be gradually reduced first by 0.1 /h until it reaches 0.3, then flow will be reduced by 10 L/min until it reaches 20 L/min. Finally, in the SR group, both the flow and FiO2 will be gradually reduced simultaneously by 10 L/min and 0.1/h, respectively. Weaning will proceed only when patients satisfy the weaning criteria at every weaning point. When the HFNC weaning-off targets are reached (20 L/min and 0.3 for flow and FiO2, respectively), the patient will be transferred to conventional oxygen therapy (mainly low-flow nasal prongs). The primary outcome is the time to successful weaning from HFNC for 24 h. Secondary outcomes will include the success or failure rate in weaning off HFNC and changes in arterial blood gas analyses, intolerance rate, length of hospital stay, and in-hospital mortality.Discussion: This study will be the first clinical trial to investigate the safety and efficacy of three different methods of weaning in adult patients receiving HFNC. Once this study is completed, we expect to be able to suggest the better strategy for withdrawal of HFNC based on the results.Trial Registration: ClinicalTrials.gov, NCT03845244. Registered on 19 February 2019. [ABSTRACT FROM AUTHOR]

Published
2020
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165. Reviews and syntheses: Ocean iron fertilization experiments – past, present, and future looking to a future Korean Iron Fertilization Experiment in the Southern Ocean (KIFES) project

Author

Yoon, Joo-Eun, primary, Yoo, Kyu-Cheul, additional, Macdonald, Alison M., additional, Yoon, Ho-Il, additional, Park, Ki-Tae, additional, Yang, Eun Jin, additional, Kim, Hyun-Cheol, additional, Lee, Jae Il, additional, Lee, Min Kyung, additional, Jung, Jinyoung, additional, Park, Jisoo, additional, Lee, Jiyoung, additional, Kim, Soyeon, additional, Kim, Seong-Su, additional, Kim, Kitae, additional, and Kim, Il-Nam, additional

Published
2018
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167. High Flow nasal OXygen therapy in high risk patients of hypoxia undergoing diagnostic BRONCHOscopy (HiFOXy-BRONCHO):a prospective, randomized, controlled study

Author

Park, Yeonkyung, primary, Kim, Youlim, additional, Park, Jisoo, additional, Kim, Eun Sun, additional, Lee, Sang Hoon, additional, Lee, Yeon Joo, additional, Park, Jong Sun, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, and Cho, Young-Jae, additional

Published
2018
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169. Evaluation of the SpO2/FiO2 ratio as a predictor of intensive care unit transfers in respiratory ward patients for whom the rapid response system has been activated

Author

Kwack, Won Gun, primary, Lee, Dong Seon, additional, Min, Hyunju, additional, Choi, Yun Young, additional, Yun, Miae, additional, Kim, Youlim, additional, Lee, Sang Hoon, additional, Song, Inae, additional, Park, Jong Sun, additional, Cho, Young-Jae, additional, Jo, You Hwan, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, and Lee, Yeon Joo, additional

Published
2018
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171. Holocene paleoceanography of Bigo Bay, west Antarctic Peninsula: Connections between surface water productivity and nutrient utilization and its implication for surface-deep water mass exchange

Author

Kim, Sunghan, primary, Yoo, Kyu-Cheul, additional, Lee, Jae Il, additional, Khim, Boo-Keun, additional, Bak, Young-Suk, additional, Lee, Min Kyung, additional, Lee, Jongmin, additional, Domack, Eugene W., additional, Christ, Andrew J., additional, and Yoon, Ho Il, additional

Published
2018
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173. Transcultural Adaptation and Validation of Quality of Dying and Death Questionnaire in Medical Intensive Care Units in South Korea

Author

Cho, Jun Yeun, primary, Lee, Jinwoo, additional, Lee, Sang-Min, additional, Park, Ju-Hee, additional, Kim, Junghyun, additional, Kim, Youlim, additional, Lee, Sang Hoon, additional, Park, Jong Sun, additional, Cho, Young-Jae, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, and Lee, Yeon Joo, additional

Published
2018
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177. Prognostic Impact of DNA Repair Protein Expression in Non-Small Cell Lung Cancers Treated with Platinum-Based Chemotherapy and Subsequent Curative Lung Resection

Author

Shin, Junghoon, primary, Lee, Kyu Sang, additional, Yoh, Kyung Ah, additional, Cho, Hyun Jin, additional, Choi, Moon Ki, additional, Kim, Se Hyun, additional, Kim, Yu Jung, additional, Chung, Jin-Haeng, additional, Cho, Sukki, additional, Kim, Kwhanmien, additional, Jheon, Sanghoon, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, and Lee, Jong Seok, additional

Published
2018
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181. Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

Author

LS IRAS EEPI GRA (Gezh.risico-analyse), dIRAS RA-2, Seow, Wei Jie, Matsuo, Keitaro, Hsiung, Chao Agnes, Shiraishi, Kouya, Song, Minsun, Kim, Hee Nam, Wong, Maria Pik, Hong, Yun-Chul, Hosgood, H. Dean, Wang, Zhaoming, Chang, I-Shou, Wang, Jiu-Cun, Chatterjee, Nilanjan, Tucker, Margaret, Wei, Hu, Mitsudomi, Tetsuya, Zheng, Wei, Kim, Jin Hee, Zhou, Baosen, Caporaso, Neil E, Albanes, Demetrius, Shin, Min-Ho, Chung, Lap Ping, An, She-Juan, Wang, Ping, Zheng, Hong, Yatabe, Yasushi, Zhang, Xu-Chao, Kim, Young Tae, Shu, Xiao Ou, Kim, Young-Chul, Bassig, Bryan A., Chang, Jiang, Ho, James Chung Man, Ji, Bu Tian, Kubo, Michiaki, Daigo, Yataro, Ito, Hidemi, Momozawa, Yukihide, Ashikawa, Kyota, Kamatani, Yoichiro, Honda, Takayuki, Sakamoto, Hiromi, Kunitoh, Hideo, Tsuta, Koji, Watanabe, Shun-Ichi, Nokihara, Hiroshi, Miyagi, Yohei, Nakayama, Haruhiko, Matsumoto, Shingo, Tsuboi, Masahiro, Goto, Koichi, Yin, Zhihua, Shi, Jianxin, Takahashi, Atsushi, Goto, Akiteru, Minamiya, Yoshihiro, Shimizu, Kimihiro, Tanaka, Kazumi, Wu, Tangchun, Wei, Fusheng, Wong, Jason Y Y, Matsuda, Fumihiko, Su, Jian, Kim, Yeul Hong, Oh, In-Jae, Song, Fengju, Lee, Victor Ho Fun, Su, Wu-Chou, Chen, Yuh-Min, Chang, Gee-Chen, Chen, Kuan-Yu, Huang, Ming-Shyan, Yang, Pan-Chyr, Lin, Hsien-Chih, Xiang, Yong-Bing, Seow, Adeline, Park, Jae Yong, Kweon, Sun-Seog, Chen, Chien-Jen, Li, Haixin, Gao, Yu Tang, Wu, Chen, Qian, Biyun, Lu, Daru, Liu, Jianjun, Jeon, Hyo-Sung, Hsiao, Chin-Fu, Sung, Jae Sook, Tsai, Ying-Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Wang, Wen-Chang, Chung, Charles C., Lawrence, Charles, Burdett, Laurie, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Berndt, Sonja I., He, Xingzhou, Wu, Wei, Wang, Junwen, Li, Yuqing, Choi, Jin Eun, Park, Kyong Hwa, Sung, Sook Whan, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung-Hsing, Yang, Tsung-Ying, Xu, Jun, Guan, Peng, Tan, Wen, Wang, Chih-Liang, Sihoe, Alan Dart Loon, Chen, Ying, Choi, Yi Young, Hung, Jen-Yu, Kim, Jun Suk, Yoon, Ho-Il, Cai, Qiuyin, Lin, Chien-Chung, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury-Perng, Chen, Chih-Yi, Vermeulen, Roel, Wu, Junjie, Lim, Wei-Yen, Chen, Kun-Chieh, Chan, John K C, Chu, Minjie, Li, Yao-Jen, Li, Jihua, Chen, Hongyan, Yu, Chong-Jen, Jin, Li, Lo, Yen-Li, Chen, Ying-Hsiang, Fraumeni, Joseph F., Liu, Jie, Yamaji, Taiki, Yang, Yang, Hicks, Belynda, Wyatt, Kathleen, Li, Shengchao A, Dai, Juncheng, Ma, Hongxia, Jin, Guangfu, Song, Bao, Wang, Zhehai, Cheng, Sensen, Li, Xuelian, Ren, Yangwu, Cui, Ping, Iwasaki, Motoki, Shimazu, Taichi, Tsugane, Shoichiro, Zhu, Junjie, Jiang, Gening, Fei, Ke, Wu, Guoping, Chien, Li-Hsin, Chen, Hui-Ling, Su, Yu-Chun, Tsai, Fang-Yu, Chen, Yi-Song, Yu, Jinming, Stevens, Victoria L, Laird-Offringa, Ite A, Marconett, Crystal N, Lin, Dongxin, Chen, Kexin, Wu, Yi-Long, Landi, Maria Teresa, Shen, Hongbing, Rothman, Nathaniel, Kohno, Takashi, Chanock, Stephen J., Lan, Qing, LS IRAS EEPI GRA (Gezh.risico-analyse), dIRAS RA-2, Seow, Wei Jie, Matsuo, Keitaro, Hsiung, Chao Agnes, Shiraishi, Kouya, Song, Minsun, Kim, Hee Nam, Wong, Maria Pik, Hong, Yun-Chul, Hosgood, H. Dean, Wang, Zhaoming, Chang, I-Shou, Wang, Jiu-Cun, Chatterjee, Nilanjan, Tucker, Margaret, Wei, Hu, Mitsudomi, Tetsuya, Zheng, Wei, Kim, Jin Hee, Zhou, Baosen, Caporaso, Neil E, Albanes, Demetrius, Shin, Min-Ho, Chung, Lap Ping, An, She-Juan, Wang, Ping, Zheng, Hong, Yatabe, Yasushi, Zhang, Xu-Chao, Kim, Young Tae, Shu, Xiao Ou, Kim, Young-Chul, Bassig, Bryan A., Chang, Jiang, Ho, James Chung Man, Ji, Bu Tian, Kubo, Michiaki, Daigo, Yataro, Ito, Hidemi, Momozawa, Yukihide, Ashikawa, Kyota, Kamatani, Yoichiro, Honda, Takayuki, Sakamoto, Hiromi, Kunitoh, Hideo, Tsuta, Koji, Watanabe, Shun-Ichi, Nokihara, Hiroshi, Miyagi, Yohei, Nakayama, Haruhiko, Matsumoto, Shingo, Tsuboi, Masahiro, Goto, Koichi, Yin, Zhihua, Shi, Jianxin, Takahashi, Atsushi, Goto, Akiteru, Minamiya, Yoshihiro, Shimizu, Kimihiro, Tanaka, Kazumi, Wu, Tangchun, Wei, Fusheng, Wong, Jason Y Y, Matsuda, Fumihiko, Su, Jian, Kim, Yeul Hong, Oh, In-Jae, Song, Fengju, Lee, Victor Ho Fun, Su, Wu-Chou, Chen, Yuh-Min, Chang, Gee-Chen, Chen, Kuan-Yu, Huang, Ming-Shyan, Yang, Pan-Chyr, Lin, Hsien-Chih, Xiang, Yong-Bing, Seow, Adeline, Park, Jae Yong, Kweon, Sun-Seog, Chen, Chien-Jen, Li, Haixin, Gao, Yu Tang, Wu, Chen, Qian, Biyun, Lu, Daru, Liu, Jianjun, Jeon, Hyo-Sung, Hsiao, Chin-Fu, Sung, Jae Sook, Tsai, Ying-Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Wang, Wen-Chang, Chung, Charles C., Lawrence, Charles, Burdett, Laurie, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Berndt, Sonja I., He, Xingzhou, Wu, Wei, Wang, Junwen, Li, Yuqing, Choi, Jin Eun, Park, Kyong Hwa, Sung, Sook Whan, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung-Hsing, Yang, Tsung-Ying, Xu, Jun, Guan, Peng, Tan, Wen, Wang, Chih-Liang, Sihoe, Alan Dart Loon, Chen, Ying, Choi, Yi Young, Hung, Jen-Yu, Kim, Jun Suk, Yoon, Ho-Il, Cai, Qiuyin, Lin, Chien-Chung, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury-Perng, Chen, Chih-Yi, Vermeulen, Roel, Wu, Junjie, Lim, Wei-Yen, Chen, Kun-Chieh, Chan, John K C, Chu, Minjie, Li, Yao-Jen, Li, Jihua, Chen, Hongyan, Yu, Chong-Jen, Jin, Li, Lo, Yen-Li, Chen, Ying-Hsiang, Fraumeni, Joseph F., Liu, Jie, Yamaji, Taiki, Yang, Yang, Hicks, Belynda, Wyatt, Kathleen, Li, Shengchao A, Dai, Juncheng, Ma, Hongxia, Jin, Guangfu, Song, Bao, Wang, Zhehai, Cheng, Sensen, Li, Xuelian, Ren, Yangwu, Cui, Ping, Iwasaki, Motoki, Shimazu, Taichi, Tsugane, Shoichiro, Zhu, Junjie, Jiang, Gening, Fei, Ke, Wu, Guoping, Chien, Li-Hsin, Chen, Hui-Ling, Su, Yu-Chun, Tsai, Fang-Yu, Chen, Yi-Song, Yu, Jinming, Stevens, Victoria L, Laird-Offringa, Ite A, Marconett, Crystal N, Lin, Dongxin, Chen, Kexin, Wu, Yi-Long, Landi, Maria Teresa, Shen, Hongbing, Rothman, Nathaniel, Kohno, Takashi, Chanock, Stephen J., and Lan, Qing

Published
2017

182. Spatial and temporal variabilities of spring Asian dust events and their impacts on chlorophyll-a concentrations in the western North Pacific Ocean

Author

Yoon, Joo-Eun, Kim, Kitae, Macdonald, Alison M., Park, Ki-Tae, Kim, Hyun-Cheol, Yoo, Kyu-Cheul, Yoon, Ho-Il, Yang, Eun Jin, Jung, Jinyoung, Lim, Jae-Hyun, Kim, Ju-Hyoung, Lee, Jiyoung, Choi, Tae-Jun, Song, Jae-Min, Kim, Il-Nam, Yoon, Joo-Eun, Kim, Kitae, Macdonald, Alison M., Park, Ki-Tae, Kim, Hyun-Cheol, Yoo, Kyu-Cheul, Yoon, Ho-Il, Yang, Eun Jin, Jung, Jinyoung, Lim, Jae-Hyun, Kim, Ju-Hyoung, Lee, Jiyoung, Choi, Tae-Jun, Song, Jae-Min, and Kim, Il-Nam

Abstract

Author Posting. © American Geophysical Union, 2017. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 44 (2017): 1474–1482, doi:10.1002/2016GL072124., As the western North Pacific Ocean is located downwind of the source regions for spring Asian dust, it is an ideal location for determining the response of open waters to these events. Spatial analysis of spring Asian dust events from source regions to the western North Pacific, using long-term daily aerosol index data, revealed three different transport pathways supported by the westerly wind system: one passing across the northern East/Japan Sea (40°N–50°N), a second moving over the entire East/Japan Sea (35°N–55°N), and a third flowing predominantly over the Siberian continent (>50°N). Our results indicate that strong spring Asian dust events can increase ocean primary productivity by more than 70% (>2-fold increase in chlorophyll-a concentrations) compared to weak/nondust conditions. Therefore, attention should be paid to the recent downturn in the number of spring Asian dust events and to the response of primary production in the western North Pacific to this change., Korean government (MSIP) Grant Numbers: 2015R1C1A1A01052051, NRF-C1ABA001-2011-0021064; Korea Polar Research Institute (KOPRI) Grant Number: PE17030; NOAA Grant Number: NA11OAR4310063; WHOI, 2017-08-15

Published
2017

183. Longitudinal changes in lung hyperinflation in COPD

Author

Park,Jimyung, Lee,Chang-Hoon, Lee,Yeon Joo, Park,Jong Sun, Cho,Young-Jae, Lee,Jae Ho, Lee,Choon-Taek, Yoon,Ho Il, Park,Jimyung, Lee,Chang-Hoon, Lee,Yeon Joo, Park,Jong Sun, Cho,Young-Jae, Lee,Jae Ho, Lee,Choon-Taek, and Yoon,Ho Il

Abstract

Jimyung Park,1 Chang-Hoon Lee,1 Yeon Joo Lee,2 Jong Sun Park,2 Young-Jae Cho,2 Jae Ho Lee,2 Choon-Taek Lee,2 Ho Il Yoon2 On behalf of the Korean Obstructive Lung Disease (KOLD) Study Group 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, 2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-Si, South Korea Purpose: COPD is characterized by an accelerated and progressive decline in forced expiratory volume in 1 second (FEV1) and lung hyperinflation. Although lung hyperinflation is the hallmark of COPD, data on the longitudinal changes in lung hyperinflation and any association with the decline in FEV1 are lacking. The aim of this study was to evaluate the longitudinal changes in lung hyperinflation and to investigate its relationship with FEV1 decline. Patients and methods: We conducted a prospective cohort study and studied 176 COPD patients with annual lung volume measurements over a period of 5 years or more. We used a random coefficient model to calculate the annual changes in lung volumes and to evaluate the factors associated with changes in lung hyperinflation. Additionally, the relationship between the change in lung hyperinflation and FEV1 was assessed. Results: Residual volume (RV), inspiratory capacity (IC), and total lung capacity (TLC) declined at a mean rate of 39.5, 49.6, and 63.8 mL/year, respectively. While IC/TLC declined at 0.70%/year, RV/TLC also declined at 0.35%/year. Changes in both IC/TLC and RV/TLC varied significantly. Frequent exacerbations led to an increase in RV/TLC and faster decline in IC/TLC over time. RV/TLC declined in 59.7% and increased in 40.3% of the patients. A significant negative correlation was found between the rates of change in FEV1 and RV/TLC, and the rate of decline in FEV1 was greater in patients with an increase in RV/TLC than in tho

Published
2017

184. Comparison of COPD Assessment Test and Clinical COPD Questionnaire to predict the risk of exacerbation

Author

Jo,Yong Suk, Yoon,Ho Il, Kim,Deog Kyeom, Yoo,Chul-Gyu, Lee,Chang-Hoon, Jo,Yong Suk, Yoon,Ho Il, Kim,Deog Kyeom, Yoo,Chul-Gyu, and Lee,Chang-Hoon

Abstract

Yong Suk Jo,1 Ho Il Yoon,2 Deog Kyeom Kim,3 Chul-Gyu Yoo,1 Chang-Hoon Lee1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, 2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi, 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea Background and objective: Guidelines recommend the use of simple but comprehensive tools such as COPD Assessment Test (CAT) and Clinical COPD Questionnaire (CCQ) to assess health status in COPD patients. We aimed to compare the ability of CAT and CCQ to predict exacerbation in COPD patients. Methods: We organized a multicenter prospective cohort study that included COPD patients. The relationships between CAT, CCQ, and other clinical measurements were analyzed by correlation analysis, and the impact of CAT and CCQ scores on exacerbation was analyzed by logistic regression analyses and receiver operating characteristic curve. Results: Among 121 COPD patients, CAT and CCQ score correlated with other symptom measures, lung function and exercise capacity as well. Compared with patients who did not experience exacerbation, those who experienced exacerbation (n=45; 38.2%) exhibited more severe airflow limitation, were more likely to have a history of exacerbation in the year prior to enrollment, and demonstrated higher CAT scores. CCQ scores were not significantly associated with exacerbations. A CAT score of ≥15 was an independent risk factor for exacerbation (adjusted odds ratio [aOR], 2.40; 95% CI, 1.03–6.50; P=0.04). Furthermore, CAT scores of ≥15 demonstrated an increased predictive ability for exacerbation compared with currently accepted guidelines for the use of CAT (≥10) and CCQ (≥1) in the assess

Published
2017

189. Effectiveness Analysis of a Part-Time Rapid Response System During Operation Versus Nonoperation*

Author

Kim, Youlim, primary, Lee, Dong Seon, additional, Min, Hyunju, additional, Choi, Yun Young, additional, Lee, Eun Young, additional, Song, Inae, additional, Park, Jong Sun, additional, Cho, Young-Jae, additional, Jo, You Hwan, additional, Yoon, Ho Il, additional, Lee, Jae Ho, additional, Lee, Choon-Taek, additional, Do, Sang Hwan, additional, and Lee, Yeon Joo, additional

Published
2017
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193. Spatial and temporal variabilities of spring Asian dust events and their impacts on chlorophyll‐ a concentrations in the western North Pacific Ocean

Author

Yoon, Joo‐Eun, primary, Kim, Kitae, additional, Macdonald, Alison M., additional, Park, Ki‐Tae, additional, Kim, Hyun‐Cheol, additional, Yoo, Kyu‐Cheul, additional, Yoon, Ho‐Il, additional, Yang, Eun Jin, additional, Jung, Jinyoung, additional, Lim, Jae‐Hyun, additional, Kim, Ju‐Hyoung, additional, Lee, Jiyoung, additional, Choi, Tae‐Jun, additional, Song, Jae‐Min, additional, and Kim, Il‐Nam, additional

Published
2017
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194. Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: study protocol for a prospective, multicenter, randomized, open-label, phase II trial

Author

Lee, Ji Yeon, primary, Kim, Deog Kyeom, additional, Lee, Jung-Kyu, additional, Yoon, Ho Il, additional, Jeong, Ina, additional, Heo, Eunyoung, additional, Park, Young Sik, additional, Lee, Jae Ho, additional, Park, Sung Soo, additional, Lee, Sang-Min, additional, Lee, Chang-Hoon, additional, Lee, Jinwoo, additional, Choi, Sun Mi, additional, Park, Jong Sun, additional, Joh, Joon-Sung, additional, Cho, Young-Jae, additional, Lee, Yeon Joo, additional, Kim, Se Joong, additional, Hwang, Young Ran, additional, Kim, Hyeonjeong, additional, Ki, Jongeun, additional, Choi, Hyungsook, additional, Han, Jiyeon, additional, Ahn, Heejung, additional, Hahn, Seokyung, additional, and Yim, Jae-Joon, additional

Published
2017
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200. Association between GWAS-identified lung adenocarcinoma susceptibility loci andEGFRmutations in never-smoking Asian women, and comparison with findings from Western populations

Author

Seow, Wei Jie, primary, Matsuo, Keitaro, additional, Hsiung, Chao Agnes, additional, Shiraishi, Kouya, additional, Song, Minsun, additional, Kim, Hee Nam, additional, Wong, Maria Pik, additional, Hong, Yun-Chul, additional, Hosgood, H. Dean, additional, Wang, Zhaoming, additional, Chang, I-Shou, additional, Wang, Jiu-Cun, additional, Chatterjee, Nilanjan, additional, Tucker, Margaret, additional, Wei, Hu, additional, Mitsudomi, Tetsuya, additional, Zheng, Wei, additional, Kim, Jin Hee, additional, Zhou, Baosen, additional, Caporaso, Neil E., additional, Albanes, Demetrius, additional, Shin, Min-Ho, additional, Chung, Lap Ping, additional, An, She-Juan, additional, Wang, Ping, additional, Zheng, Hong, additional, Yatabe, Yasushi, additional, Zhang, Xu-Chao, additional, Kim, Young Tae, additional, Shu, Xiao-Ou, additional, Kim, Young-Chul, additional, Bassig, Bryan A., additional, Chang, Jiang, additional, Ho, James Chung Man, additional, Ji, Bu-Tian, additional, Kubo, Michiaki, additional, Daigo, Yataro, additional, Ito, Hidemi, additional, Momozawa, Yukihide, additional, Ashikawa, Kyota, additional, Kamatani, Yoichiro, additional, Honda, Takayuki, additional, Sakamoto, Hiromi, additional, Kunitoh, Hideo, additional, Tsuta, Koji, additional, Watanabe, Shun-Ichi, additional, Nokihara, Hiroshi, additional, Miyagi, Yohei, additional, Nakayama, Haruhiko, additional, Matsumoto, Shingo, additional, Tsuboi, Masahiro, additional, Goto, Koichi, additional, Yin, Zhihua, additional, Shi, Jianxin, additional, Takahashi, Atsushi, additional, Goto, Akiteru, additional, Minamiya, Yoshihiro, additional, Shimizu, Kimihiro, additional, Tanaka, Kazumi, additional, Wu, Tangchun, additional, Wei, Fusheng, additional, Wong, Jason Y.Y., additional, Matsuda, Fumihiko, additional, Su, Jian, additional, Kim, Yeul Hong, additional, Oh, In-Jae, additional, Song, Fengju, additional, Lee, Victor Ho Fun, additional, Su, Wu-Chou, additional, Chen, Yuh-Min, additional, Chang, Gee-Chen, additional, Chen, Kuan-Yu, additional, Huang, Ming-Shyan, additional, Yang, Pan-Chyr, additional, Lin, Hsien-Chih, additional, Xiang, Yong-Bing, additional, Seow, Adeline, additional, Park, Jae Yong, additional, Kweon, Sun-Seog, additional, Chen, Chien-Jen, additional, Li, Haixin, additional, Gao, Yu-Tang, additional, Wu, Chen, additional, Qian, Biyun, additional, Lu, Daru, additional, Liu, Jianjun, additional, Jeon, Hyo-Sung, additional, Hsiao, Chin-Fu, additional, Sung, Jae Sook, additional, Tsai, Ying-Huang, additional, Jung, Yoo Jin, additional, Guo, Huan, additional, Hu, Zhibin, additional, Wang, Wen-Chang, additional, Chung, Charles C., additional, Lawrence, Charles, additional, Burdett, Laurie, additional, Yeager, Meredith, additional, Jacobs, Kevin B., additional, Hutchinson, Amy, additional, Berndt, Sonja I., additional, He, Xingzhou, additional, Wu, Wei, additional, Wang, Junwen, additional, Li, Yuqing, additional, Choi, Jin Eun, additional, Park, Kyong Hwa, additional, Sung, Sook Whan, additional, Liu, Li, additional, Kang, Chang Hyun, additional, Hu, Lingmin, additional, Chen, Chung-Hsing, additional, Yang, Tsung-Ying, additional, Xu, Jun, additional, Guan, Peng, additional, Tan, Wen, additional, Wang, Chih-Liang, additional, Sihoe, Alan Dart Loon, additional, Chen, Ying, additional, Choi, Yi Young, additional, Hung, Jen-Yu, additional, Kim, Jun Suk, additional, Yoon, Ho-Il, additional, Cai, Qiuyin, additional, Lin, Chien-Chung, additional, Park, In Kyu, additional, Xu, Ping, additional, Dong, Jing, additional, Kim, Christopher, additional, He, Qincheng, additional, Perng, Reury-Perng, additional, Chen, Chih-Yi, additional, Vermeulen, Roel, additional, Wu, Junjie, additional, Lim, Wei-Yen, additional, Chen, Kun-Chieh, additional, Chan, John K.C., additional, Chu, Minjie, additional, Li, Yao-Jen, additional, Li, Jihua, additional, Chen, Hongyan, additional, Yu, Chong-Jen, additional, Jin, Li, additional, Lo, Yen-Li, additional, Chen, Ying-Hsiang, additional, Fraumeni, Joseph F., additional, Liu, Jie, additional, Yamaji, Taiki, additional, Yang, Yang, additional, Hicks, Belynda, additional, Wyatt, Kathleen, additional, Li, Shengchao A., additional, Dai, Juncheng, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Song, Bao, additional, Wang, Zhehai, additional, Cheng, Sensen, additional, Li, Xuelian, additional, Ren, Yangwu, additional, Cui, Ping, additional, Iwasaki, Motoki, additional, Shimazu, Taichi, additional, Tsugane, Shoichiro, additional, Zhu, Junjie, additional, Jiang, Gening, additional, Fei, Ke, additional, Wu, Guoping, additional, Chien, Li-Hsin, additional, Chen, Hui-Ling, additional, Su, Yu-Chun, additional, Tsai, Fang-Yu, additional, Chen, Yi-Song, additional, Yu, Jinming, additional, Stevens, Victoria L., additional, Laird-Offringa, Ite A., additional, Marconett, Crystal N., additional, Lin, Dongxin, additional, Chen, Kexin, additional, Wu, Yi-Long, additional, Landi, Maria Teresa, additional, Shen, Hongbing, additional, Rothman, Nathaniel, additional, Kohno, Takashi, additional, Chanock, Stephen J., additional, and Lan, Qing, additional

Published
2016
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