170 results on '"Yi-Fan Wu"'
Search Results
152. Pulmonary function and incident bronchitis and asthma in children: a community-based prospective cohort study
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Yu An Chen, Yungling Leo Lee, Bing-Fang Hwang, Jer-Min Chen, and Yi-Fan Wu
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Male ,Pediatrics ,medicine.medical_specialty ,Environmental Engineering ,Pulmonology ,Adolescent ,Epidemiology ,Science ,Population ,Taiwan ,Pulmonary function testing ,symbols.namesake ,Engineering ,Medicine ,Humans ,Poisson regression ,Prospective Studies ,Prospective cohort study ,education ,Adverse effect ,Bronchitis ,Child ,Biology ,Lung ,Asthma ,education.field_of_study ,Multidisciplinary ,Population Biology ,business.industry ,medicine.disease ,Respiratory Function Tests ,symbols ,Earth Sciences ,Female ,Public Health ,business ,Environmental Sciences ,Cohort study ,Research Article - Abstract
BackgroundPrevious studies revealed that reduction of airway caliber in infancy might increase the risks for wheezing and asthma. However, the evidence for the predictive effects of pulmonary function on respiratory health in children was still inconsistent.MethodsWe conducted a population-based prospective cohort study among children in 14 Taiwanese communities. There were 3,160 children completed pulmonary function tests in 2007 and follow-up questionnaire in 2009. Poisson regression models were performed to estimate the effect of pulmonary function on the development of bronchitis and asthma.ResultsAfter adjustment for potential confounders, pulmonary function indices consistently showed protective effects on respiratory diseases in children. The incidence rate ratios of bronchitis and asthma were 0.86 (95% CI 0.79-0.95) and 0.91 (95% CI 0.82-0.99) for forced expiratory volume in 1 second (FEV₁). Similar adverse effects of maximal mid-expiratory flow (MMEF) were also observed on bronchitis (RR = 0.73, 95% CI 0.67-0.81) and asthma (RR = 0.85, 95% CI 0.77-0.93). We found significant decreasing trends in categorized FEV₁ (p for trend = 0.02) and categories of MMEF (p for trend = 0.01) for incident bronchitis. Significant modification effects of traffic-related air pollution were noted for FEV₁ and MMEF on bronchitis and also for MMEF on asthma.ConclusionsChildren with high pulmonary function would have lower risks on the development of bronchitis and asthma. The protective effect of high pulmonary function would be modified by traffic-related air pollution exposure.
- Published
- 2012
153. [Advances in parallel artificial membrane permeability assay and its applications]
- Author
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Yi-Fan, Wu, Hui, Liu, and Jing-Man, Ni
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Cell Membrane Permeability ,Intestinal Absorption ,Pharmaceutical Preparations ,Blood-Brain Barrier ,Gastric Mucosa ,Skin Absorption ,Animals ,Humans ,Membranes, Artificial ,Permeability ,Absorption - Abstract
With the development of drug discovery, more and more candidate compounds need to be studied. Methods that can screen compound rapidly received significant attention. Parallel artificial membrane permeability assay (PAMPA) as a powerful tool has been applied to drug studies. It uses an artificial lipid membrane to mimic the barrier for drug permeability studies. This article introduces the establishment and characteristics of PAMPA, as well as its applications in screening compounds. It can be used as models (e.g. predicting the ability of compound in gastro-intestinal absorption, blood-brain barrier transportation and skin penetration) by changing the component of artificial lipid membrane. PAMPA has advantages in high throughput selection of valuable compound with low cost, versatile, low dose, and good reproducibility.
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- 2011
154. Blind Identification of Noncausal ARNMA-Hammestein System
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Rong-yan Li, Yun-shi Xiao, and Yi-fan Wu
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Nonlinear system ,Identification (information) ,Mathematical optimization ,Generalization ,Kernel (statistics) ,Volterra series ,Autoregressive–moving-average model ,Blind signal separation ,Algorithm ,Linear least squares ,Mathematics - Abstract
A novel nonlinear model is proposed for nonlinear system blind identification with infinite memory. This model is a generalization and combination of both ARMA model and Volterra-Hammestein(NMA-Hammestein) model. In the process of blind identification, two steps are involved. First, we focused on the left part(AR) of model form,which could be identified by using the generalized BBR formula and MYW(modified Yule-Walker) normal equation. Then, the problem changes into the blind identification of Volterra-Hammestein model, thus several methods could be employed. The simulation results showed its good estimation performance for nonlinear system.
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- 2010
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155. [Analysis of Chinese medicine syndrome types in 156 patients undergoing maintenance peritoneal dialysis]
- Author
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Yi-fan, Wu, Xu-sheng, Liu, and Chun-lin, Huang
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Adult ,Aged, 80 and over ,Inflammation ,Male ,C-Reactive Protein ,Peritoneal Dialysis, Continuous Ambulatory ,Humans ,Female ,Medicine, Chinese Traditional ,Middle Aged ,Serum Albumin ,Aged - Abstract
To analyze the Chinese medicine syndrome types of patients undergoing maintenance peritoneal dialysis to provide some clinical reference for the treatment based on syndromes.According to the criterion made by the Nephropathy Branch of China Association of Chinese Medicine in 2006, the syndrome type of 156 patients were differentiated, and the related laboratory parameters, including serum albumin (ALB), C-reactive protein (CRP), hemoglobin (HB), total urea clearance rate (KT/Vt), residual kidney urea clearance (KT/Vr), blood flow mediated vascular endothelial dilatation (FMD) and volume overload (OH) were measured.Syndrome type presented in patients was different. Along with the progress of dialysis, it changed in the root syndromes from qi-deficiency to yang-deficiency and further to both yin-yang deficiency, while in the superficial syndromes it turned from turbid-damp to blood-stasis. ALB in patients with Pi-shen yang-deficiency type and both yin-yang deficiency type was significantly lower than that in patients with Pi-Shen qi-deficiency type and both qi-yin deficiency type (P0.05); KT/Vt in both yin-yang deficiency type was the lowest, significantly lower than that in Gan-Shen yin-deficiency type and both qi-yin deficiency (P0.05); OH in Pi-Shen yang-deficiency type and both yin-yang deficiency type was significantly higher than that in other types (P0.01). Comparison of patients' age showed that group of patients without superficial syndrome was the youngest and the group of patients with damp-heat syndrome type was the oldest (P0.01). CRP in damp-heat type was significantly higher than that in other types (P0.05); FMD was lower in blood-stasis type than in turbid-damp type and toxic heat type (P0.01); and OH was significantly higher in turbid-damp type than in other types (P0.01).Some rules of syndrome type distribution could be seen in patients undergoing peritoneal dialysis, which is related with some laboratory parameters to a certain extent, so may provide a few references for clinical treatment based on syndrome type.
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- 2010
156. Studies of Drug Delivery and Drug Release of Dendrimer by Dissipative Particle Dynamics
- Author
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Chun-Min Lin, Yi-Fan Wu, Heng-Kwong Tsao, Yu-Jane Sheng, Michio Tokuyama, Irwin Oppenheim, and Hideya Nishiyama
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chemistry.chemical_classification ,Partition coefficient ,Materials science ,Aqueous solution ,chemistry ,Chemical engineering ,Biomolecule ,Dendrimer ,Dissipative particle dynamics ,Drug delivery ,Organic chemistry ,Drug carrier ,Micelle - Abstract
Dendrimers, like unimolecular micelles, may encapsulate guest biomolecules (drug) and therefore are attractive candidates as carriers in drug delivery applications. Hydrophobic drugs can be complexed within the hydrophobic dendrimer interior to make them water‐soluble. The equilibrium partition of hydrophobic solutes into a dendrimer with hydrophobic interior from aqueous solutions is studied by dissipative particle dynamics. The drug is mainly distributed in the vicinity of the interface between hydrophobic interior and hydrophilic exterior within a dendrimer. The partition coefficient, which is defined as the concentration ratio of the drug distributed within dendrimer to aqueous phases, depends on the interaction between drug and hydrophilic dendrimer exterior. Increasing the repulsion between them reduces the solubilization ability associated with the dendrimer.
- Published
- 2008
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157. The feasibility of using manual segmentation in a multifeature computer-aided diagnosis system for classification of skin lesions: a retrospective comparative study
- Author
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Yin-Chun Chen, Yi-Fan Wu, Adam Huang, Gwo-Shing Chen, Chi-Wei Lin, Wen-Yu Chang, Chung-Kai Yang, Yin-Tseng Huang, and John Tsai
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Adult ,Male ,medicine.medical_specialty ,Skin Neoplasms ,Intraclass correlation ,Dermatology ,Malignancy ,Sensitivity and Specificity ,Skin Diseases ,Decision Support Techniques ,Diagnosis, Differential ,Image Interpretation, Computer-Assisted ,Photography ,medicine ,Humans ,Segmentation ,Aged ,Retrospective Studies ,Observer Variation ,Receiver operating characteristic ,business.industry ,Research ,General Medicine ,Gold standard (test) ,Middle Aged ,medicine.disease ,Surgery ,ROC Curve ,Feature (computer vision) ,Computer-aided diagnosis ,Feasibility Studies ,Female ,Radiology ,Differential diagnosis ,business ,Algorithms ,Software - Abstract
Objectives To investigate the feasibility of manual segmentation by users of different backgrounds in a previously developed multifeature computer-aided diagnosis (CADx) system to classify melanocytic and non-melanocytic skin lesions based on conventional digital photographic images. Methods In total, 347 conventional photographs of melanocytic and non-melanocytic skin lesions were retrospectively reviewed, and manually segmented by two groups of physicians, dermatologists and general practitioners, as well as by an automated segmentation software program, JSEG. The performance of CADx based on inputs from these two groups of physicians and that of the JSEG program was compared using feature agreement analysis. Results The estimated area under the receiver operating characteristic curve for classification of benign or malignant skin lesions based were comparable on individual segmentation by the gold standard (0.893, 95% CI 0.856 to 0.930), dermatologists (0.886, 95% CI 0.863 to 0.908), general practitioners (0.883, 95% CI 0.864 to 0.903) and JSEG (0.856, 95% CI 0.812 to 0.899). The agreement in the malignancy probability scores among the physicians was excellent (intraclass correlation coefficient: 0.91). By selecting an optimal cut-off value of malignancy probability score, the sensitivity and specificity were 80.07% and 81.47% for dermatologists and 79.90% and 80.20% for general practitioners. Conclusions This study suggests that manual segmentation by general practitioners is feasible in the described CADx system for classifying benign and malignant skin lesions.
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- 2015
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158. Left Ventricular Diastolic Dysfunction in Peritoneal Dialysis
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Jen Kuang Lee, Cho-Kai Wu, Kuan-Yu Hung, Jenq-Wen Huang, Jou-Wei Lin, Chia Ti Tsai, Jiunn Lee Lin, Fu-Tien Chiang, Yi Fan Wu, and Juey-Jen Hwang
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Observational Study ,Article ,Peritoneal dialysis ,Ventricular Dysfunction, Left ,Tissue Doppler echocardiography ,Diastole ,Risk Factors ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,Risk factor ,Proportional hazards model ,business.industry ,Hazard ratio ,Confounding ,General Medicine ,Middle Aged ,Prognosis ,Echocardiography, Doppler ,Confidence interval ,Surgery ,C-Reactive Protein ,Adipose Tissue ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Cardiology ,Female ,business ,Peritoneal Dialysis ,Mace - Abstract
Supplemental Digital Content is available in the text, Left ventricular diastolic dysfunction (LVDD) is common among patients undergoing peritoneal dialysis (PD). We examined the relationship between LVDD, major adverse cardiovascular events (MACE), and mortality in PD patients. A total of 149 patients undergoing PD with preserved left ventricular systolic function were included and followed for 3.5 years. LVDD was diagnosed (according to the European Society of Cardiology guidelines) by conventional and tissue Doppler echocardiography. Serum high-sensitivity C-reactive protein (hsCRP) was measured. The location and volume of adipose tissue were assessed by computed tomography (CT) at the level of the fourth lumbar vertebra. Subjects with LVDD had higher levels of hsCRP, and more visceral and peritoneal fat than controls. The relationship between adjusted visceral adipose tissue and LVDD became nonsignificant when hsCRP and baseline demographic data were introduced into the logistic regression model (odds ratio = 1.52, P = 0.07). Subsequent hierarchical multivariate Cox regression analysis showed that LVDD was one of the most powerful determinants of MACE and mortality after adjusting for all confounding factors (hazard ratio [HR]: 1.71, 95% confidence interval [CI]: 1.43–3.51, P = 0.02 and HR: 2.25, 95% CI: 1.45–2.91, P = 0.04, respectively). Systemic inflammation (hsCRP) was also significantly associated with MACE and mortality (HR: 2.03, P = 0.03 and HR: 2.16, P = 0.04, respectively). LVDD is associated with systemic inflammation and increased visceral fat in patients undergoing PD. LVDD is also a sensitive, independent indicator of future MACE and mortality in PD patients.
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- 2015
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159. Chloroquine inhibits Ca2+ permeable ion channels-mediated Ca2+ signaling in primary B lymphocytes.
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Yi-Fan Wu, Ping Zhao, Xi Luo, Jin-Chao Xu, Lu Xue, Qi Zhou, Mingrui Xiong, Jinhua Shen, Yong-Bo Peng, Meng-Fei Yu, Weiwei Chen, Liqun Ma, and Qing-Hua Liu
- Subjects
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CHLOROQUINE , *THAPSIGARGIN , *B cells - Abstract
Background: Chloroquine, a bitter tastant, inhibits Ca2+ signaling, resulting in suppression of B cell activation; however, the inhibitory mechanism remains unclear. Results: In this study, thapsigargin (TG), but not caffeine, induced sustained intracellular Ca2+ increases in mouse splenic primary B lymphocytes, which were markedly inhibited by chloroquine. Under Ca2+- free conditions, TG elicited transient Ca2+ increases, which additionally elevated upon the restoration of 2 mM Ca2+. The former were from release of intracellular Ca2+ store and the latter from Ca2+ influx. TG-induced release was inhibited by 2-APB (an inhibitor of inositol-3-phosphate receptors, IP3Rs) and chloroquine, and TG-caused influx was inhibited by pyrazole (Pyr3, an inhibitor of transient receptor potential C3 (TRPC3) and stromal interaction molecule (STIM)/Orai channels) and chloroquine. Moreover, chloroquine also blocked Ca2+ increases induced by the engagement of B cell receptor (BCR) with anti-IgM. Conclusions: These results indicate that chloroquine inhibits Ca2+ elevations in splenic B cells through inhibiting Ca2+ permeable IP3R and TRPC3 and/or STIM/Orai channels. These findings suggest that chloroquine would be a potent immunosuppressant. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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160. [Biological characteristics of mesenchymal stem cells in human umbilical cord blood and their supporting capacities in ex vivo expansion of CD34+ hematopoietic stem cells]
- Author
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Li-juan, Wang, Ye-ping, Zhang, Jin-fu, Wang, Yi-fan, Wu, Ying, Xiang, Chun-gang, Xie, Bing-bing, Jia, Jenny, Harrington, and Ian K, McNiece
- Subjects
Reverse Transcriptase Polymerase Chain Reaction ,Gene Expression ,Antigens, CD34 ,Cell Differentiation ,Enzyme-Linked Immunosorbent Assay ,Mesenchymal Stem Cells ,Fetal Blood ,Hematopoietic Stem Cells ,Coculture Techniques ,Cell Adhesion ,Cytokines ,Humans ,Collagen Type II ,Cells, Cultured ,Cell Proliferation - Abstract
To explore the biological characteristics of mesenchymal stem cells (MSC) derived from umbilical cord blood (UCB) and their supporting capacities in ex vivo expansion of hematopoietic stem/progenitor cells (HSPCs).Low-density mononuclear cells (MNCs) from UCB were cultured in IMDM containing 20% FBS to form confluent adherent cells through 15 passages. Some cytokines in the conditioned medium were determined with ELISA. UCB-derived adherent cells were displayed with antibodies and analyzed with flow cytometry. The supporting capacity of UCB-derived adherent cells for ex vivo expansion of CD34(+) cells was assayed by co-culture in a two step culture. UCB-derived adherent cells were induced for chondrogenic differentiation with chondrogenic medium, and the induced cells were analyzed for the type II pro-collagen gene expression with RT-PCR.The mean number of adherent fibroblast like colonies derived from UCB was (3.5 +/- 0.7)/10(6) MNCs. UCB-derived MSCs could survive for at least 15 passages of expansion. In their undifferentiated status, UCB-derived MSCs were CD13(+), CD29(+), CD90(+), CD105(+), CD166(+), SH2(+), SH3(+), SH4(+), CD45(-), CD34(-), and CD14(-). Stem cell factor (SCF), interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-alpha) could be detected in the supernatant of the cultures. The MSCs cultured in chondrogenic media could differentiate into chondrogenic cells and express type II pro-collagen mRNA. UCB-derived MSCs could support the proliferation and differentiation of UCB CD34(+) cells in vitro.UCB-derived MSCs are similar to those derived from adult bone marrow and can support the proliferation of hematopoietic stem/progenitor cells.
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- 2005
161. Mesenchymal stem/progenitor cells in human umbilical cord blood as support for ex vivo expansion of CD34(+) hematopoietic stem cells and for chondrogenic differentiation
- Author
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Jin-Fu, Wang, Li-Juan, Wang, Yi-Fan, Wu, Ying, Xiang, Chun-Gang, Xie, Bing-Bing, Jia, Jenny, Harrington, and Ian K, McNiece
- Subjects
Adult ,Stem Cells ,Antigens, CD34 ,Cell Differentiation ,Mesenchymal Stem Cells ,Fibroblasts ,Fetal Blood ,Hematopoietic Stem Cells ,Immunophenotyping ,Cartilage ,Cell Adhesion ,Humans ,Female ,Chondrogenesis ,Cells, Cultured - Abstract
Human mesenchymal stem/progenitor cells (MSPC) ar pluripotent, being the precursors for marrow stroma, bone, cartilage, muscle and connective tissues. Although the presence of hematopoietic stem/progenitor cells (HSPC) in umbilical cord blood (UCB) is well known, that of MSPC has been not fully evaluated.In this study, we examined the immunophenotype, the supporting function in relation to ex vivo expansion of hematopoietic stem progenitor cells and the chondrogenic differentiation of cultured cells with characteristics of MSPC from UCB. When UCB nucleated cells were isolated and 107 cells cultured in IMDM with 20% fetal bovine serum, the mean number of adherent fibroblastlike colonies was 3.5+/-0.7/10(6) monuclear cells.UCB-derived MSPC could be expanded for at least 15 passages. In their undifferentiated state, UCB-derived MSPC were CD13(+), CD29(+), CD90(+), CD105(+), CD166(+), SH2(+), SH3(+), SH4(+), CD45(-), CD34(-), and CD14(-); they produced stem cell factor, interleukin 6 and tumor necrosis factor alpha. UCB-derived MSPC cultured in chondrogenic media differentiated into chondrogenic cells. UCB-derived MSPC supported the proliferation and differentiation of CD34(+) cells from UCB in vitro.UCB-derived MSPC have the potential to support ex vivo expansion of HSPC and chondrogenic differentiation. UCB should not be regarded as medical waste. It can serve as an alternative source of mesenchymal stem cells and may provide a unique source of fetal cells for cellular and gene therapy.
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- 2004
162. Research on routing model for MANET based on quantum search algorithm
- Author
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Li-min, Meng, primary, Yi-fan, Wu, additional, Jing-yu, Hua, additional, and Zhi-jiang, Xu, additional
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- 2010
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163. Left Ventricular Diastolic Dysfunction in Peritoneal Dialysis A Forgotten Risk Factor.
- Author
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Cho-Kai Wu, Jen-Kuang Lee, Yi-Fan Wu, Chia-Ti Tsai, Fu-Tien Chiang, Juey-Jen Hwang, Jiunn-Lee Lin, Kuan-Yu Hung, Jenq-Wen Huang, and Jou-Wei Lin
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- 2015
- Full Text
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164. The feasibility of using manual segmentation in a multifeature computer-aided diagnosis system for classification of skin lesions: a retrospective comparative study.
- Author
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Wen-Yu Chang, Adam Huang, Yin-Chun Chen, Chi-Wei Lin, Tsai, John, Chung-Kai Yang, Yin-Tseng Huang, Yi-Fan Wu, and Gwo-Shing Chen
- Abstract
Objectives: To investigate the feasibility of manual segmentation by users of different backgrounds in a previously developed multifeature computer-aided diagnosis (CADx) system to classify melanocytic and non-melanocytic skin lesions based on conventional digital photographic images. Methods: In total, 347 conventional photographs of melanocytic and non-melanocytic skin lesions were retrospectively reviewed, and manually segmented by two groups of physicians, dermatologists and general practitioners, as well as by an automated segmentation software program, JSEG. The performance of CADx based on inputs from these two groups of physicians and that of the JSEG program was compared using feature agreement analysis. Results: The estimated area under the receiver operating characteristic curve for classification of benign or malignant skin lesions based were comparable on individual segmentation by the gold standard (0.893, 95% CI 0.856 to 0.930), dermatologists (0.886, 95% CI 0.863 to 0.908), general practitioners (0.883, 95% CI 0.864 to 0.903) and JSEG (0.856, 95% CI 0.812 to 0.899). The agreement in the malignancy probability scores among the physicians was excellent (intraclass correlation coefficient: 0.91). By selecting an optimal cut-off value of malignancy probability score, the sensitivity and specificity were 80.07% and 81.47% for dermatologists and 79.90% and 80.20% for general practitioners. Conclusions: This study suggests that manual segmentation by general practitioners is feasible in the described CADx system for classifying benign and malignant skin lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
165. Environmental and lifestyle factors of obesity.
- Author
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YI-WEN CHIEN, TAI-YIN WU, KUANG-YANG LIN, YI-FAN WU, KUAN-LIANG KUO, and WEI-CHU CHIE
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OBESITY risk factors ,ENVIRONMENTAL impact analysis ,SOCIAL factors ,SOCIAL status ,QUALITY of life ,STATURE ,FOOD habits ,SLEEP deprivation - Abstract
Obesity is the fifth leading risk factor of death globally. Obesity causes diseases related to metabolic syndrome individually and creates medical and financial burdens nationally. Many factors contribute to obesity including factors classified as hereditary or genetic, environmental, lifestyle, and endocrine or medical in nature. The aim of this paper is to explore the effects of environmental and lifestyle factors on the increasing obesity rates in Taiwan in recent years using three components. (1) Family component: to discuss the relationship between family socioeconomic status, quality of family life, parental body stature, changes in dietary habits and increased sedentary activity and obesity. (2) School component: to explore the relationship between decreased exercise and sleep deprivation due to academic pressure and obesity. (3) Societal component: to explore the relationship between Western-style fast food, sugar-sweetened beverages, the impact of mass media, fat tax and obesity. In this paper, we review existing literature and available statistics and propose potentially feasible solutions to the issue of obesity in hopes that through governmental policy implementation, this significant health problem in the people of Taiwan can be ameliorated. [ABSTRACT FROM AUTHOR]
- Published
- 2013
166. A Reconfigurable Quadri-Polarization Diversity Aperture-Coupled Patch Antenna.
- Author
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Yi-Fan Wu, Chun-Hsien Wu, Don-Yen Lai, and Fu-Chiarng Chen
- Subjects
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LOCAL area networks , *COMPUTER networks , *WIRELESS LANs , *FRAME relay (Data transmission) , *DIODES - Abstract
We present a novel reconfigurable quadri-polarization diversity aperture-coupled patch antenna which can provide four polarization states. By controlling the dc bias voltage of the pin-diodes on the feeding network, we can reconfigure the proposed antenna to provide a pair of orthogonal linear polarizations and a pair of orthogonal circular polarizations. Numerical and experimental results validate our design. This novel antenna provides potential polarization diversity features for wireless local area networks and multiple-input multiple-output systems. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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167. Adhering to a Tai Chi Chuan Exercise Program Improves Vascular Resistance and Cardiac Function
- Author
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Chun-Hsiung Wang, Yin-Tsen Huang, and Yi-Fan Wu
- Subjects
Cardiac function curve ,aged population ,medicine.medical_specialty ,Cardiac output ,Tai Chi Chuan ,Population ,Cardiac index ,Hemodynamics ,lcsh:Geriatrics ,Internal medicine ,medicine ,adherence ,education ,education.field_of_study ,Ejection fraction ,vascular resistance ,business.industry ,Stroke volume ,lcsh:RC952-954.6 ,medicine.anatomical_structure ,Vascular resistance ,Physical therapy ,Cardiology ,Geriatrics and Gerontology ,cardiac function ,business - Abstract
Summary Background Cardiac function is an important predictor for life expectancy in elderly subjects. Tai Chi Chuan (TCC) is a generalized tolerable exercise for the aged population. The current study evaluated the effects of TCC on the vascular compliance and resistance as well as cardiac function of a general healthy elderly population. Materials and methods A total of 122 consecutive subjects were enrolled from the general population. Yang style TCC was practiced three times a week for 1hour each session for a duration of 5 months. Subjects were categorized as "adherents" ( n =33) if they participated in >48 (80%) sessions, or as "non-adherents" ( n =34). Biochemistry data, including fasting glucose, serum cholesterol, triglycerides, uric acid, were recorded before and after the 5-month intervention. Hemodynamic variables, including vascular compliance, resistance, cardiac output, stroke volume, and left ventricular ejection fraction, were obtained before and after the program using a Dynapulse 200M monitor. Results Serum triglyceride levels declined after TCC practice (the changes in triglycerides were −3.12 mg/dL and 18.8 mg/dL for the adherent and non-adherent groups, respectively; p =0.03). Significant differences between the adherent and non-adherent groups existed in left ventricular contractility, cardiac output, cardiac index, stroke volume, and brachial artery compliance ( p p =0.01; p p p =0.02, respectively). Conclusion A 5-month TCC intervention can have a favorable impact on some biochemical indices of cardiovascular risk. This intervention can also have favorable effects upon hemodynamic parameters. These findings indicate that TCC intervention may offer enhanced cardioprotective effects in the aged population.
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168. Modeling shear-induced particle ordering and deformation in a dense soft particle suspension.
- Author
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Chih-Tang Liao, Yi-Fan Wu, Wei Chien, Jung-Ren Huang, and Yeng-Long Chen
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- 2017
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169. A two-stage stochastic programming model for rail-truck intermodal network design with uncertain customer demand.
- Author
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Shu-Xia Li, Si-Fan Sun, Yi-Fan Wu, and Li-Ping Liu
- Subjects
- *
RAILROAD design & construction , *STOCHASTIC programming , *CONTAINERIZATION , *SUPPLY chains , *COST effectiveness - Abstract
With the globalization of supply chains, intermodal operations have become a key player in transportation. In real life, the consumer's demands are often uncertain. The recent literature is rich of papers that either emphasizes on uncertain customer demands or intermodal transportation planning. In this paper, we combine these two fields in order to identify new potentials for saving cost and improving the efficiency of intermodal logistics network. A two stage stochastic programming model was proposed to decide the terminal location and transportation routes under uncertain customer demands. And the AP data set is used to test the presented model. The result is compared with the traditional counterparts, which shows superiority in solution quantity under uncertain environment. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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170. Between "Homeland" and "Foreign Country": Liminal Identity and Boundary Work of Taiwanese Students in China.
- Author
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Pei-Chia Lan and Yi-Fan Wu
- Subjects
STUDENTS ,HIGHER education ,GRADUATION (Education) ,EMIGRATION & immigration ,GROUP identity ,TAIWANESE people ,EDUCATION - Abstract
Based on 61 in-depth interviews with Taiwanese students who moved to China for higher education, our study examines how migratory experience impacts the configuration and transformation of national identities. In particular, we explore how migrant students negotiate their ambiguous subject positions in webs of discourses that are interwoven between Taiwan and China, between China-as-imagined and China-in reality, and between "homeland" and "foreign country." We demonstrate how students re-identify "us" and "them" during personal encounters while living in China, and how they utilize a variety of everyday practices to highlight or downplay the boundaries between themselves and locals. We propose a map of boundary work to analyze migrants' heterogeneous positions and multifarious experiences. We identify three major types of boundary work, as follows: (1) Some students are inclined to leave China after graduation and emphasize the existence of radical differences between Chinese and Taiwanese; this strategy is most common among those who emigrated to study for degrees. (2) Some students are inclined to stay in China and become incorporated into the local society to a higher degree, such as those whose parents work in China as professionals and those who came to China for job prospects. (3) The others choose to stay in China but highlight the boundaries between themselves and locals by deploying spatial and social segregation; examples include those whose parents run businesses in China and those who seek cross-region employment and mobility. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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