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Globally, in 2016, 1 out of 11 adults suffered from diabetes mellitus. Diabetic foot ulcers (DFU) are a major complication of this disease, which if not managed properly can lead to amputation. Current clinical approaches to DFU treatment rely on patient and clinician vigilance, which has significant limitations, such as the high cost involved in the diagnosis, treatment, and lengthy care of the DFU. We collected an extensive dataset of foot images, which contain DFU from different patients. In this DFU classification problem, we assessed the two classes as normal skin (healthy skin) and abnormal skin (DFU). In this paper, we have proposed the use of machine learning algorithms to extract the features for DFU and healthy skin patches to understand the differences in the computer vision perspective. This experiment is performed to evaluate the skin conditions of both classes that are at high risk of misclassification by computer vision algorithms. Furthermore, we used convolutional neural networks for the first time in this binary classification. We have proposed a novel convolutional neural network architecture, DFUNet, with better feature extraction to identify the feature differences between healthy skin and the DFU. Using 10-fold cross validation, DFUNet achieved an AUC score of 0.961. This outperformed both the traditional machine learning and deep learning classifiers we have tested. Here, we present the development of a novel and highly sensitive DFUNet for objectively detecting the presence of DFUs. This novel approach has the potential to deliver a paradigm shift in diabetic foot care among diabetic patients, which represent a cost-effective, remote, and convenient healthcare solution.

Micro-facial expressions are regarded as an important human behavioural event that can highlight emotional deception. Spotting these movements is difficult for humans and machines, however research into using computer vision to detect subtle facial expressions is growing in popularity. This paper proposes an individualised baseline micro-movement detection method using 3D Histogram of Oriented Gradients (3D HOG) temporal difference method. We define a face template consisting of 26 regions based on the Facial Action Coding System (FACS). We extract the temporal features of each region using 3D HOG. Then, we use Chi-square distance to find subtle facial motion in the local regions. Finally, an automatic peak detector is used to detect micro-movements above the newly proposed adaptive baseline threshold. The performance is validated on two FACS coded datasets: SAMM and CASME II. This objective method focuses on the movement of the 26 face regions. When comparing with the ground truth, the best result was an AUC of 0.7512 and 0.7261 on SAMM and CASME II, respectively. The results show that 3D HOG outperformed for micro-movement detection, compared to state-of-the-art feature representations: Local Binary Patterns in Three Orthogonal Planes and Histograms of Oriented Optical Flow.