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677 results on '"Yao, Shunyu"'

157. Temperature Control and Monitoring of Mass Concrete in Flood Control Wall Floor

Author

PENG Qian, YAO Shunyu, LIU Zhanling, and YANG Wanlun

Subjects
mass concrete, temperature crack, temperature control, temperature monitoring, monitoring data analysis, River, lake, and water-supply engineering (General), TC401-506
Abstract

In the process of mass concrete construction,the crack temperature control directly affects the quality of construction.Taking the mass concrete construction of a flood control wall floor in Huangpu River as an example,in order to avoid the occurrence of harmful cracks,this paper takes the corresponding temperature control measures,and conducts the temperature monitoring.The measured data of typical measuring points show that the inner surface,surface and environmental temperature differences of each measuring point are within the limits,and no temperature cracks are found on the concrete surface after removal of form,which verifies the rationality of the design and temperature control construction measures,and provides guidance for the implementation of subsequent projects.

Published
2021
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163. The Current Progresses and Future Perspectives of Photoreactors and Catalysts Used in Photocatalytic Reduction of CO2

Author

Shu, Kaiyou, primary, Guan, Bin, additional, Guo, Jiangfeng, additional, Wu, Xingze, additional, Chen, Yujun, additional, Ma, Zeren, additional, Zhang, Jinhe, additional, Chen, JunYan, additional, Yao, ShunYu, additional, Bao, Shibo, additional, Jiang, Xing, additional, Chen, Lei, additional, Dang, Hongtao, additional, Guo, Zelong, additional, Li, Zekai, additional, Hu, JingQiu, additional, Yi, Chao, additional, and Huang, Zhen, additional

Published
2023
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165. Antibody–Calixarene Drug Conjugate: A General Drug Delivery Platform for Tumor-Targeted Therapy

Author

Wu, Xueyao, Yao, Shunyu, Huang, Qingqing, Ying, Ankang, Li, Qiushi, Cao, Xianghui, Wang, Chun, Xiao, Jian, Feng, Nana, Zhang, Zhanzhan, Guo, Dongsheng, and liu, Yang

Abstract

Antibody–drug conjugates (ADCs), which combine the precise targeting capabilities of antibodies with the powerful cytotoxicity of small-molecule drugs, have evolved into a promising approach for tumor treatment. However, the traditional covalent coupling method requires the design of a specific linker tailored to the properties of the small-molecule drugs, which greatly limits the development of ADCs and the range of drugs that can be used. Herein, a novel type of antibody–calixarene drug conjugates (ACDCs) that function similarly to ADCs by delivering drugs to their targets using antibodies but without the requirement of covalent conjugation of the drugs with antibodies is presented. By replacement of conventional linkers with supramolecular linkers, the ACDCs can load various chemotherapeutic drugs through host–guest interactions. Furthermore, ACDCs are readily reduced upon reaching the hypoxic microenvironment, resulting in rapid release of the drugs. With this precise drug encapsulation and controlled release mechanism, ACDCs deliver drugs to tumor tissues effectively and achieve a significantly enhanced antitumor effect. Considering that the ACDCs can be easily prepared by combining antibody–calixarene conjugates derived from tumor-targeting antibodies with various small-molecule drugs, ACDCs may provide a promising platform technology to accelerate ADC development and thus improve the therapeutic efficacy of chemotherapy.

Published
2024
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179. Research Status, Challenges, and Future Prospects of Carbon Dioxide Reduction Technology

Author

Dang, Hongtao, Guan, Bin, Chen, Junyan, Ma, Zeren, Chen, Yujun, Zhang, Jinhe, Guo, Zelong, Chen, Lei, Hu, Jingqiu, Yi, Chao, Yao, Shunyu, and Huang, Zhen

Abstract

The survival and sustainable development of humanity are gravely threatened by climate change, which has recently been elevated to the status of one of the greatest threats to humanity’s survival and security on a worldwide scale. In response to global climate change, how to obtain renewable and clean fuels is an important challenge for the sustainable development of human society. In order to reach the carbon peak and attain carbon neutrality, using CO2as a resource has become a crucial aim for human civilization. Converting CO2into chemical products with higher added value, that is, CO2resource utilization technology can not only achieve CO2emission reduction but also have certain economic benefits. The technologies of CO2resource utilization primarily include photocatalytic reduction, electrocatalytic reduction, thermal catalytic reduction, and relay catalysis. This paper mainly summarizes the mechanism of CO2catalytic conversion technologies and the research status of related catalysts, and summarizes and discusses prospects for the development of the CO2catalytic reduction system (catalyst modification, product selectivity improvement, etc.). The ideas and guidance are provided for the development of efficient and stable CO2reduction catalysts and the application of CO2catalytic reduction technology in the areas of environment and energy.

Published
2024
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182. A Case of Multiple Myeloma-Associated Systemic Amyloidosis with Multiple Skin Manifestations as the First Symptom

Author

Yao,Shunyu, Wang,Suxia, Yi,Runxi, Ran,Liwei, Zhang,Cang, Yao,Shunyu, Wang,Suxia, Yi,Runxi, Ran,Liwei, and Zhang,Cang

Abstract

Shunyu Yao,1,2 Suxia Wang,3,* Runxi Yi,1,4,* Liwei Ran,5 Cang Zhang2 1Chinese Traditional Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, People’s Republic of China; 3Laboratory of Electron Microscopy, Pathological Center, Peking University First Hospital, Beijing, People’s Republic of China; 4Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, People’s Republic of China; 5Department of Dermatology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Liwei Ran, Department of Dermatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, People’s Republic of China, Tel +86 010 85231374, Email wlbrlw@163.com Cang Zhang, Department of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, 23 Back Street of Art Gallery, Dongcheng District, Beijing, 100010, People’s Republic of China, Tel +86 13693219292, Email zhangcang@bjzhongyi.comAbstract: An 81-year-old woman presented with purpura, petechiae, ecchymoses, flesh or brown-colored waxy, smooth, papules, warty plaque, nail dystrophy and palmodigital erythematous swelling for more than 6 years. She was diagnosed as multiple myeloma-associated systemic amyloidosis after skin subcutaneous histopathological examinations and relevant examinations such as blood and bone marrow. Systemic amyloidosis is closely related with multiple myeloma (MM). Multiple and pleomorphic skin lesions are not usual among patients with multiple myeloma or systemic amyloidosis.Keywords: multiple myeloma, primary systemic amyloidosis, monoclonal immunoglobulin

Published
2023

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