151. Comparison of total splenic artery embolization and partial splenic embolization for hypersplenism.
- Author
-
He XH, Gu JJ, Li WT, Peng WJ, Li GD, Wang SP, Xu LC, and Ji J
- Subjects
- Adult, Chi-Square Distribution, China, Embolization, Therapeutic adverse effects, Female, Humans, Hypersplenism blood, Hypersplenism diagnosis, Length of Stay, Leukocyte Count, Male, Middle Aged, Patient Selection, Platelet Count, Prospective Studies, Risk Assessment, Risk Factors, Time Factors, Tomography, X-Ray Computed, Treatment Outcome, Embolization, Therapeutic methods, Hypersplenism therapy, Splenic Artery diagnostic imaging
- Abstract
Aim: To evaluate whether total splenic artery embolization (TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization (PSE)., Methods: Sixty-one patients with hypersplenism eligible for TSAE (n = 27, group A) or PSE (n = 34, group B) were enrolled into the trial, which included clinical and computed tomography follow-up. Data on technical success, length of hospital stay, white blood cell (WBC) and platelet (PLT) counts, splenic volume and complications were collected at 2 wk, 6 mo, and 1, 2, 3, 4 years postoperatively., Results: Both TSAE and PSE were technically successful in all patients. Complications were significantly fewer (P = 0.001), and hospital stay significantly shorter (P = 0.007), in group A than in group B. Post-procedure WBC and PLT counts in group A were significantly higher than those in group B from 6 mo to 4 years (P = 0.001), and post-procedure residual splenic volume in group A was significantly less than that observed in group B at 1, 2, 3 and 4 years post-procedure (P = 0.001). No significant differences were observed in red blood cell counts and liver function parameters between the two groups following the procedure., Conclusion: Our results indicate that TSAE for patients with hypersplenism not only delivers a better long-term outcome, but is also associated with lower complication rates and a shorter hospital stay than PSE.
- Published
- 2012
- Full Text
- View/download PDF