8,417 results on '"Xin, Lin"'
Search Results
152. Behind the Screens: Exploring Eye Movement Visualization to Optimize Online Teaching and Learning.
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Marian Sauter, Tobias Wagner 0002, Teresa Hirzle, Bao Xin Lin, Enrico Rukzio, and Anke Huckauf
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- 2023
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153. Towards a Holistic Understanding of Mathematical Questions with Contrastive Pre-training.
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Yuting Ning, Zhenya Huang, Xin Lin 0005, Enhong Chen, Shiwei Tong, Zheng Gong 0001, and Shijin Wang 0001
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- 2023
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154. A Disentangled-Attention Based Framework with Persona-Aware Prompt Learning for Dialogue Generation.
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Pingsheng Liu, Zhengjie Huang, Xiechi Zhang, Linlin Wang, Gerard de Melo, Xin Lin 0001, Liang Pang, and Liang He 0001
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- 2023
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155. Leveraging Transferable Knowledge Concept Graph Embedding for Cold-Start Cognitive Diagnosis.
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Weibo Gao, Hao Wang 0076, Qi Liu 0003, Fei Wang 0063, Xin Lin 0005, Linan Yue, Zheng Zhang 0048, Rui Lv, and Shijin Wang 0001
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- 2023
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156. Approach for Along-Track Baseline Distribution Design in a Multi-Satellite Distributed Space-Based Radar System.
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Jiangyuan Chen, Penghui Huang, Peili Xi, Xin Lin 0002, Lihuan Huo, Yongyan Sun, Guozhong Chen, and Xingzhao Liu
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- 2023
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157. An Optimal Beam Design Algorithm for Space-Based Early Warning Radar Systems.
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Jiangyuan Chen, Penghui Huang, Xin Lin 0002, Donghong Wang, Peili Xi, Yongyan Sun, Guozhong Chen, and Xingzhao Liu
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- 2023
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158. F2DLNet: A Face Forgery Detection and Localization Network Based on SSIM Error Maps
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Peng, Fei, Zhang, Xin-lin, Long, Min, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Xu, Yuan, editor, Yan, Hongyang, editor, Teng, Huang, editor, Cai, Jun, editor, and Li, Jin, editor
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- 2023
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159. The role of miR1 and miR133a in new-onset atrial fibrillation after acute myocardial infarction
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Qingyi Zeng, Wei Li, Zhenghua Luo, Haiyan Zhou, Zhonggang Duan, and Xin Lin Xiong
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New-onset atrial fibrillation ,Acute myocardial infarction ,miR1 ,miR133a ,Inflammation ,Glasgow prognostic score ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background The development of new-onset atrial fibrillation (NOAF) after acute myocardial infarction (AMI) is a clinical complication that requires a better understanding of the causative risk factors. This study aimed to explore the risk factors and the expression and function of miR-1 and miR-133a in new atrial fibrillation after AMI. Methods We collected clinical data from 172 patients with AMI treated with emergency percutaneous coronary intervention (PCI) between October 2021 and October 2022. Independent predictors of NOAF were determined using binary logistic univariate and multivariate regression analyses. The predictive value of NOAF was assessed using the area under the receiver operating characteristic (ROC) curve for related risk factors. In total, 172 venous blood samples were collected preoperatively and on the first day postoperatively; the expression levels of miR-1 and miR-133a were determined using the polymerase chain reaction. The clinical significance of miR-1 and miR-133a expression levels was determined by Spearman correlation analysis. Results The Glasgow prognostic score, left atrial diameter, and infarct area were significant independent risk factors for NOAF after AMI. We observed that the expression levels of miR-1 and miR-133a were significantly higher in the NOAF group than in the non-NOAF group. On postoperative day 1, strong associations were found between miR-133a expression levels and the neutrophil ratio and between miR-1 expression levels and an increased left atrial diameter. Conclusions Our findings indicate that the mechanism of NOAF after AMI may include an inflammatory response associated with an increased miR-1-related mechanism. Conversely, miR-133a could play a protective role in this clinical condition.
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- 2023
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160. Engineering fine grains, dislocations and precipitates for enhancing the strength of TiB2-modified CoCrFeMnNi high-entropy alloy using laser powder bed fusion
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Zhao Chen, Xiaoli Wen, Weili Wang, Xin Lin, Haiou Yang, Ze Jiang, Lianyang Chen, Haibin Wu, Wenhui Li, and Nan Li
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Laser powder bed fusion ,CoCrFeMnNi+TiB2 composite ,Microstructures ,Mechanical properties ,Strengthening mechanisms ,Mining engineering. Metallurgy ,TN1-997 - Abstract
TiB2 nano-particle reinforced CoCrFeMnNi composite has been additively manufactured by using laser powder bed fusion (LPBF) technique. In comparison with the matrix CoCrFeMnNi sample, the average grain size of the TiB2 doped CoCrFeMnNi (CoCrFeMnNi + TiB2) sample reduces from 26.27 μm to 7.51 μm, appearing a morphological transformation from columnar grains to fine equiaxed grains and fine dendritic grains. Correspondingly, the compressive yield strength (σy) sharply increases from 484.41 ± 57.81 MPa of CoCrFeMnNi HEA to 952.62 ± 38.15 MPa of CoCrFeMnNi + TiB2, and the tensile yield strength increases from 480.27 ± 1.25 MPa to 834.21 ± 15.93 MPa, revealing a substantial enhancement of mechanical properties. The structural analysis unveils that the CoCrFeMnNi + TiB2 sample formed a tetragonal σ phase beside the FCC matrix and TiB2 phases compared with the single FCC phase of CoCrFeMnNi HEA. Especially, atomic resolution scanning transmission electron microscopy discloses that the TiB2 nanoparticles epitaxially grow onto the FCC matrix phase with [01–10]TiB2//[011]FCC orientation relationship. Theoretical calculations indicate that the enhancement mechanism of the CoCrFeMnNi + TiB2 sample should originate from a synergistic strengthening effect which is induced by grain refinement, TiB2 particles, σ phases and dislocations. Our work should provide a new view to utilize the rapid solidification process of LPBF and ceramic nano-particle reinforcement for the enhanced mechanical properties of HEAs with great potential.
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- 2023
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161. Uridine alleviates high-carbohydrate diet-induced metabolic syndromes by activating sirt1/AMPK signaling pathway and promoting glycogen synthesis in Nile tilapia (Oreochromis niloticus)
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Nan-Nan Zhou, Tong Wang, Yu-Xin Lin, Rong Xu, Hong-Xia Wu, Fei-Fei Ding, Fang Qiao, Zhen-Yu Du, and Mei-Ling Zhang
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Uridine ,High-carbohydrate diet ,Metabolism ,AMPK ,Nile tilapia ,Animal culture ,SF1-1100 - Abstract
Carbohydrates have a protein sparing effect, but long-term feeding of a high-carbohydrate diet (HCD) leads to metabolic disorders due to the limited utilization efficiency of carbohydrates in fish. How to mitigate the negative effects induced by HCD is crucial for the rapid development of aquaculture. Uridine is a pyrimidine nucleoside that plays a vital role in regulating lipid and glucose metabolism, but whether uridine can alleviate metabolic syndromes induced by HCD remains unknown. In this study, a total of 480 Nile tilapia (Oreochromis niloticus) (average initial weight 5.02 ± 0.03 g) were fed with 4 diets, including a control diet (CON), HCD, HCD + 500 mg/kg uridine (HCUL) and HCD + 5,000 mg/kg uridine (HCUH), for 8 weeks. The results showed that addition of uridine decreased hepatic lipid, serum glucose, triglyceride and cholesterol (P
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- 2023
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162. Effects of Dopamine on stem cells and its potential roles in the treatment of inflammatory disorders: a narrative review
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Guan-qiao Liu, Zi-xian Liu, Ze-xin Lin, Peng Chen, Yu-chi Yan, Qing-rong Lin, Yan-jun Hu, Nan Jiang, and Bin Yu
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Dopamine ,Neuron stem cell ,Mesenchymal stromal cell ,Hematopoietic stem cell ,Cancer stem cell ,Inflammatory disorders ,Medicine (General) ,R5-920 ,Biochemistry ,QD415-436 - Abstract
Abstract Inflammation is the host's protective response against harmful external stimulation that helps tissue repair and remodeling. However, excessive inflammation seriously threatens the patient's life. Due to anti-inflammatory effects, corticosteroids, immunosuppressants, and monoclonal antibodies are used to treat various inflammatory diseases, but drug resistance, non-responsiveness, and severe side effect limit their development and application. Therefore, developing other alternative therapies has become essential in anti-inflammatory therapy. In recent years, the in-depth study of stem cells has made them a promising alternative drug for the treatment of inflammatory diseases, and the function of stem cells is regulated by a variety of signals, of which dopamine signaling is one of the main influencing factors. In this review, we review the effects of dopamine on various adult stem cells (neural stem cells, mesenchymal stromal cells, hematopoietic stem cells, and cancer stem cells) and their signaling pathways, as well as the application of some critical dopamine receptor agonists/antagonists. Besides, we also review the role of various adult stem cells in inflammatory diseases and discuss the potential anti-inflammation function of dopamine receptors, which provides a new therapeutic target for regenerative medicine in inflammatory diseases.
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- 2023
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163. The influence of media use degree on public depressive symptoms: mediating role of big five personality
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Fangmin Gong, Yuhan Jia, Xinying Sun, Hewei Min, Xiaocen Jia, Fei Wang, Xincheng Huang, Xin Lin, Zheming Li, and Yibo Wu
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Media use ,Big five personality ,Depressive symptoms ,Mediation model ,Regression analysis ,Psychiatry ,RC435-571 - Abstract
Abstract Background Mixed results have been found regarding the relationship between media use degree and depressive symptoms. The purpose of this study is to explore the relationship between media use degree, big five personality and depressive symptoms with a mediation model. Method This was a cross-sectional study. With 9-item Patient Health Questionnaire (PHQ-9), 10-item Big Five Inventory (BFI-10) and self-designed media usage scale, 11,031 participants aged 12 and above in 120 cities in China were collected. Pearson correlation analysis and regression analysis were performed on the data. The Process plug-in was used to construct the mediation model and explore the relationship among media use degree, big five personality and depressive symptoms. The nonparametric percentile Bootstrap method was used to test the mediating effect of personality traits. Results The degree of media use was positively correlated with depressive symptoms (r = 0.20, P
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- 2023
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164. Heterozygous CARD9 mutation favors the development of allergic bronchopulmonary aspergillosis
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Xia Xu, Haiwen Lu, Jianxiong Li, Jielin Duan, Zhongwei Wang, Jiawei Yang, Shuyi Gu, Rongguang Luo, Shuo Liang, Wei Tang, Fengying Zhang, Jingqing Hang, Juan Ge, Xin Lin, Jieming Qu, Xinming Jia, Jinfu Xu, Xiangxiang Pan, and Peifang Wei
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Medicine - Abstract
Abstract. Background:. Previous research demonstrated that a homozygous mutation of g.136372044G>A (S12N) in caspase recruitment domain family member 9 (CARD9) is critical for producing Aspergillus fumigatus-induced (Af-induced) T helper 2 (TH2)-mediated responses in allergic bronchopulmonary aspergillosis (ABPA). However, it remains unclear whether the CARD9S12N mutation, especially the heterozygous occurrence, predisposes the host to ABPA. Methods:. A total of 61 ABPA patients and 264 controls (including 156 healthy controls and 108 asthma patients) were recruited for sequencing the CARD9 locus to clarify whether patients with this heterozygous single-nucleotide polymorphisms are predisposed to the development of ABPA. A series of in vivo and in vitro experiments, such as quantitative real-time polymerase chain reaction, flow cytometry, and RNA isolation and quantification, were used to illuminate the involved mechanism of the disease. Results:. The presence of the p.S12N mutation was associated with a significant risk of ABPA in ABPA patients when compared with healthy controls and asthma patients, regardless of Aspergillus sensitivity. Relative to healthy controls without relevant allergies, the mutation of p.S12N was associated with a significant risk of ABPA (OR: 2.69 and 4.17 for GA and AA genotypes, P = 0.003 and 0.029, respectively). Compared with patients with asthma, ABPA patients had a significantly higher heterozygous mutation (GA genotype), indicating that p.S12N might be a significant ABPA-susceptibility locus (aspergillus sensitized asthma: OR: 3.02, P = 0.009; aspergillus unsensitized asthma: OR: 2.94, P = 0.005). The mutant allele was preferentially expressed in ABPA patients with heterozygous CARD9S12N, which contributes to its functional alterations to facilitate Af-induced TH2-mediated ABPA development. In terms of mechanism, Card9 wild-type (Card9WT) expression levels decreased significantly due to Af-induced decay of its messenger RNA compared to the heterozygous Card9S12N. In addition, ABPA patients with heterozygous CARD9S12N had increased Af-induced interleukin-5 production. Conclusion:. Our study provides the genetic evidence showing that the heterozygous mutation of CARD9S12N, followed by allele expression imbalance of CARD9S12N, facilitates the development of ABPA.
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- 2023
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165. Association of preoperative CA-125 levels with early POAF after heart valve surgery: a single-center, retrospective study
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Xiaoqin Liao, Sailan Li, Xin Yan, Xin Lin, Liangwan Chen, and Yanjuan Lin
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Postoperative atrial fibrillation ,Cancer antigen-125 ,Cardiac surgery ,Valve surgery ,Surgery ,RD1-811 - Abstract
Abstract Objective Cancer antigen-125 (CA-125), a tumor marker, has received increasing attention in recent years for its role in the cardiovascular field. However, no study has reported the association of CA-125 with early postoperative atrial fibrillation (POAF) after heart valve surgery. Therefore, the aim of this study was to assess whether there is a correlation between CA-125 and early postoperative POAF after heart valve surgery. Methods Patients who underwent valve surgery at Fujian Heart Medical Center from January 2020 to August 2022 were retrospectively analyzed and divided into postoperative atrial fibrillation group (POAF group) and postoperative non-atrial fibrillation group (NO-POAF), and the differences in clinical data between the two groups were compared, and the variables with statistical significance in the univariate analysis were included in the COX regression analysis, and finally the receivers’ operating characteristics (ROC) curves were drawn. Results From January 2020 to August 2022, a total of 1653 patients underwent valve surgery. A total of 344 patients were finally included, including 52 patients (15.1%) in the POAF group and 292 patients (84.9%) in the NO-POAF group. Univariate analysis showed higher CA-125 levels in patients in the POAF group than in those in the NO-POAF group [27.89 (13.64, 61.54), 14.48 (9.87, 24.08), P = 0.000]. Analysis of the incidence of POAF based on CA-125 quartiles showed an incidence of up to 29.2% in the highest quartile (> 27.88). Multivariate COX regression analysis showed that CA-125 [OR = 1.006, 95% CI (1.002, 1.010), P = 0.001] was an independent predictor of POAF. The final ROC curve plot showed that the area under the curve for CA-125 was 0.669, with an optimal cut-off value of 27.08 U/ml, and the difference in the area under the curve between the two groups was statistically significant (P = 0.000). Conclusion Elevated preoperative CA-125 levels can affect the incidence of POAF and have a predictive value for the occurrence of POAF in the early stage after valve surgery. However, due to the small sample size and single-center retrospective study, further validation of this result is needed.
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- 2023
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166. Genomic and immune characteristics of HER2‐mutated non‐small‐cell lung cancer and response to immune checkpoint inhibitor‐based therapy
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Hai‐Yan Tu, Kai Yin, Xiaotian Zhao, E‐E Ke, Si‐Pei Wu, Yang‐Si Li, Mei‐Mei Zheng, Si‐Yang Maggie Liu, Chong‐Rui Xu, Yue‐Li Sun, Jia‐Xin Lin, Xiao‐Yan Bai, Yi‐Chen Zhang, Qing Zhou, Jin‐Ji Yang, Wen‐Zhao Zhong, Bing‐Chao Wang, Xu‐Chao Zhang, Dongqin Zhu, Lingling Yang, Qiuxiang Ou, and Yi‐Long Wu
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advanced NSCLC ,exon 20 insertion ,human epidermal growth factor receptor 2 ,immune checkpoint inhibitor ,non‐exon 20 insertion ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
The efficacy of immunotherapy in advanced HER2‐mutated non‐small‐cell lung cancer (NSCLC) remains incomprehensively studied. A total of 107 NSCLC patients with de novo HER2 mutations were retrospectively studied at Guangdong Lung Cancer Institute [GLCI cohort, exon 20 insertions (ex20ins): 71.0%] to compare clinical/molecular features and immune checkpoint inhibitor (ICI)‐based therapy efficacy between patients with ex20ins and non‐ex20ins. Two external cohorts (TCGA, n = 21; META‐ICI, n = 30) were used for validation. In the GLCI cohort, 68.2% of patients displayed programmed death‐ligand 1 (PD‐L1) expression
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- 2023
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167. Ocean acidification has a strong effect on communities living on plastic in mesocosms
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Xu Zhang, Ping Zhang, Zichao Deng, Ruiping Huang, Di Zhang, Yang Tian, Na Wang, He Li, Xuyang Wang, Xiaowen Jiang, Jiazhen Sun, Qianqian Fu, Xiangqi Yi, Liming Qu, Cong Zhou, Yuming Rao, Xiaorong Zeng, Jason M. Hall‐Spencer, Guang Gao, Kunshan Gao, and Xin Lin
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Oceanography ,GC1-1581 - Abstract
Abstract We conducted a mesocosm experiment to examine how ocean acidification (OA) affects communities of prokaryotes and eukaryotes growing on single‐use drinking bottles in subtropical eutrophic waters of the East China Sea. Based on 16S rDNA gene sequencing, simulated high CO2 significantly altered the prokaryotic community, with the relative abundance of the phylum Planctomycetota increasing by 49%. Under high CO2, prokaryotes in the plastisphere had enhanced nitrogen dissimilation and ureolysis, raising the possibility that OA may modify nutrient cycling in subtropical eutrophic waters. The relative abundance of pathogenic and animal parasite bacteria also increased under simulated high CO2. Our results show that elevated CO2 levels significantly affected several animal taxa based on 18S rDNA gene sequencing. For example, Mayorella amoebae were highly resistant, whereas Labyrinthula were sensitive to OA. Thus, OA may alter plastisphere food chains in subtropical eutrophic waters.
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- 2023
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168. Solidification texture dependence of the anisotropy of mechanical properties and damping capacities of an AZ31 Mg-based alloy fabricated via wire-arc additive manufacturing
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Zihong Wang, Jingfeng Wang, Xin Lin, Tianchi Zhang, Cong Dang, Yanfang Wang, Weidong Huang, and Fushen Pan
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Wire-arc additive manufacturing ,Magnesium alloy ,Anisotropy ,Mechanical properties ,Damping capacities ,Mining engineering. Metallurgy ,TN1-997 - Abstract
Wire-arc additive manufacturing (WAAM) offers a brand-new method for short process and rapid manufacturing of large magnesium alloy components, which can avoid the formability dilemma faced by Mg alloys due to their poor plasticity. In this study, the relationships between the solidification texture and the anisotropy of mechanical properties/damping capacities of an AZ31 Mg-based alloy fabricated by the WAAM process were studied. The results revealed that the crystallographic texture with the (0001) basal plane along the building direction was promoted by the preferential growth of dendrite arms along the direction of the HCP crystal structure. The (0001) basal texture had a strong influence on the anisotropy of mechanical properties and damping capacities. Compared to the sample with a tensile axis perpendicular to the building direction, the sample with a tensile axis along the building direction displays a simultaneous increase in tensile strength and ductility, which is related to the smaller Schmid factor (SF) for basal slip and better plasticity deformation via non-basal slip and twinning. However, the smaller SF for basal slip also results in a smaller resolved shear stress factor for the breakaway stress during the damping response testing, resulting in lower damping capacities. This work is helpful for further optimizing the mechanical properties and damping capacities of WAAM-processed Mg-based alloys.
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- 2023
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169. Risk factors for the recurrence in pulmonary tuberculosis patients with massive hemoptysis
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Qiong Lin, Jian Chen, Tianxing Yu, Bing Gao, Kaijin Kuang, Yong Fan, Junping Xu, Xiaohua Li, Xin Lin, and Liyu Xu
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embolization ,massive hemoptysis ,prognosis ,pulmonary tuberculosis ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Objectives To evaluate the outcomes of bronchial artery embolization (BAE) for the treatment of massive hemoptysis in patients with pulmonary tuberculosis and identify risk factors that influence recurrence. Methods A total of 81 patients with massive hemoptysis who underwent BAE between January 2014 and December 2017 were retrospectively reviewed. All of the patients had either a history of pulmonary tuberculosis or a current diagnosis of pulmonary tuberculosis. Follow‐up ranged from 18 to 66 months. Results Hemoptysis was stopped or markedly decreased, with subsequent clinical improvement in 73 patients, while 11 patients experienced recurrence during the follow‐up period. Systemic‐pulmonary shunts and clinical failure showed a statistically significant correlation with the recurrence rate. The cumulative non‐recurrence rate was 95.3% for 3 months and 81.9% for more than 24 months. Complications were common (12.5%), but self‐limiting. Conclusions BAE is a safe and effective treatment option for the control of massive hemoptysis in pulmonary tuberculosis patients. Systemic‐pulmonary shunts and clinical failure are the risk factors for recurrence.
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- 2023
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170. Anal fistulotomy with one-stage shaped skin grafting for intersphincter anal fistulas: study protocol on a multicentre randomised controlled trial
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Yongchang Zhao, Wei Xie, Xiaoshuo Wu, Xiaolan Li, Jinyan Guo, Qiurui Cao, Jiadi Liang, Xin-lin Chen, Wentao Zhao, Feng Sun, Hongjie Li, Weimin Luo, and Yuying Li
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Anal fistula ,Anal fistulotomy ,Randomised controlled trial ,Skin graft ,Medicine (General) ,R5-920 - Abstract
Abstract Background Anal fistulas are mainly treated via surgery. They can be difficult to treat without surgical intervention. Numerous procedures, such as fistulectomy and fistulotomy, are performed to treat anal fistulas and achieve good effects. However, the wounds created through fistulectomy and fistulotomy take a long time to heal. Therefore, a multicentre randomised controlled trial (RCT) is proposed to study the efficacy of one-stage shaped skin grafting at the surgical wound to heal low simple intersphincter anal fistulas. Methods This study is a multicentre, hospital-based RCT. It will be performed at three hospitals. A total of 104 patients with low simple intersphincter anal fistulas who meet the inclusion criteria will be included in this trial and will be allocated randomly to two groups (test and control groups). The patients in the test group will receive one-stage anal fistulotomy surgery combined with shaped skin grafting, and those in the control group will undergo anal fistulotomy only. All the operations will be performed by attending colorectal surgeons or surgeons of a higher level. Effectiveness and safety indicators will be observed, recorded and analysed. Discussion Anal fistulotomy can heal low simple intersphincter anal fistulas effectively and safely with a low recurrence rate. Skin grafts promote wound epithelisation significantly. We believe that skin grafting can treat low simple intersphincter fistulas with a short healing time. Trial registration Chinese Clinical Trial Register, ChiCTR2000039174. Registered on 28 October 2020.
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- 2023
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171. A Daubechies wavelet analysis on coupled radiation and conduction in absorbing and scattering medium under pulsed laser
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Shi, Yu, Xia, Xin-Lin, Chen, Xue, and Chuang, Sun
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- 2024
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172. Prevalence and factors associated with depression and anxiety among older adults: A large-scale cross-sectional study in China
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He, Zhen-fan, Tan, Wen-yan, Ma, Huilin, Shuai, Yuxing, Shan, Zejun, Zhai, Jiaxiang, Qiu, Yifeng, Zeng, Honghao, Chen, Xin-lin, Wang, Shi-bin, and Liu, Yu
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- 2024
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173. Experimental characterization of Al2O3 foam based on high temperature thermal response experiments
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Shi, Yu, Chen, Xue, and Xia, Xin-Lin
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- 2024
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174. Hydrogel electrolyte membrane with regulated pore effect to stabilize zinc anode in aqueous zinc-ion batteries
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Yan, Lei, Zhang, Qi, Zhang, Ze, Li, Gui-Jie, Jin, Yi, Zhang, Xin-Lin, and Sun, Yan-Yun
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- 2024
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175. Composite solid-state electrolytes with fast ion channels constructed from in-situ hydrogen bonding and coupling/crosslinking effects for dendrite-free solid-state lithium batteries
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Zhang, Qi, Yan, Lei, Fan, Lei, Jin, Yi, Zhang, Xin-Lin, and Sun, Yan-Yun
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- 2024
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176. A multispectral radiometry method for measuring the normal spectral emissivity and temperature
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Li, Jia-Qi, Xia, Xin-Lin, Sun, Chuang, Chen, Xue, and Wang, Qin-Yang
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- 2024
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177. Deterministic Localization for Fully Automatic Operation: A Survey and Experiments
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Wan-Ning He and Xin-Lin Huang
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deterministic localization ,certainty ,interference mitigation ,anchor deployment ,Chemical technology ,TP1-1185 - Abstract
With the rapid development of fully automatic operation (FAO) and location-based services, the evaluation criteria of average localization accuracy can no longer meet our demands, in favor of deterministic localization. However, most localization researches modeled localization performance function and enhanced it by minimizing average localization root mean square error (RMSE). The performance degradation in a small region was not considered. In this paper, we present a survey of deterministic localization and analyze the relationship between accuracy and certainty. In this paper, two common solutions of localization enhancement are presented and their localization certainties are discussed. Furthermore, we carry out related localization enhancement experiments in rail transit line and analyze their improvement on deterministic localization. The experimental results show that the overall localization performance is improved, while the deterministic localization requires the stricter solution to promote.
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- 2024
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178. Integrated ATAC-seq and RNA-seq Analysis of In Vitro Cultured Skeletal Muscle Satellite Cells to Understand Changes in Cell Proliferation
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Zeyu Ren, Siyi Zhang, Liangyu Shi, Ao Zhou, Xin Lin, Jing Zhang, Xiusheng Zhu, Lei Huang, and Kui Li
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pig ,satellite cells ,cell proliferation ,ATAC-seq ,Cytology ,QH573-671 - Abstract
Skeletal muscle satellite cells, the resident stem cells in pig skeletal muscle, undergo proliferation and differentiation to enable muscle tissue repair. The proliferative and differentiative abilities of these cells gradually decrease during in vitro cultivation as the cell passage number increases. Despite extensive research, the precise molecular mechanisms that regulate this process are not fully understood. To bridge this knowledge gap, we conducted transcriptomic analysis of skeletal muscle satellite cells during in vitro cultivation to quantify passage number-dependent changes in the expression of genes associated with proliferation. Additionally, we explored the relationships between gene transcriptional activity and chromatin accessibility using transposase-accessible chromatin sequencing. This revealed the closure of numerous open chromatin regions, which were primarily located in intergenic regions, as the cell passage number increased. Integrated analysis of the transcriptomic and epigenomic data demonstrated a weak correlation between gene transcriptional activity and chromatin openness in expressed genic regions; although some genes (e.g., GNB4 and FGD5) showed consistent relationships between gene expression and chromatin openness, a substantial number of differentially expressed genes had no clear association with chromatin openness in expressed genic regions. The p53-p21-RB signaling pathway may play a critical regulatory role in cell proliferation processes. The combined transcriptomic and epigenomic approach taken here provided key insights into changes in gene expression and chromatin openness during in vitro cultivation of skeletal muscle satellite cells. These findings enhance our understanding of the intricate mechanisms underlying the decline in cellular proliferation capacity in cultured cells.
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- 2024
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179. Conversion of Phosphogypsum into Porous Calcium Silicate Hydrate for the Removal and Recycling of Pb(II) and Cd(II) from Wastewater
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Gangan Wang, Chaoyi Chen, Junqi Li, Yuanpei Lan, Xin Lin, and Jiahang Chen
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phosphogypsum ,porous calcium silicate hydrate ,competitive interaction ,adsorption mechanism ,stepwise desorption ,Organic chemistry ,QD241-441 - Abstract
The discharge of lead and cadmium wastewater, along with the pollution caused by phosphogypsum, represents a particularly urgent environmental issue. This study employed a straightforward hydrothermal method to convert phosphogypsum into porous calcium silicate hydrate (P-CSH), which was then used to remove and recover Pb(II) and Cd(II) from wastewater. The adsorption capacities of P-CSH for Pb(II) and Cd(II) were notably high at 989.3 mg/g and 290.3 mg/g, respectively. The adsorption processes adhered to the pseudo-second-order kinetics model and the Langmuir isotherm model. Due to identical adsorption sites on P-CSH for both Pb(II) and Cd(II), competitive interaction occurred when both ions were present simultaneously. Additionally, the adsorption efficacy was minimally impacted by the presence of common coexisting cations in wastewater. The dominant mechanisms for removing Pb(II) and Cd(II) via P-CSH were chemical precipitation and surface complexation. Moreover, the adsorbed heavy metals were efficiently separated and reclaimed from the wastewater through a stepwise desorption process. The primary components of the residue from stepwise desorption were quartz and amorphous SiO2. Following dissolution via pressurized alkaline leaching, this residue could be recycled for synthesizing P-CSH. This research offered a new strategy for the resourceful use of phosphogypsum and heavy metal wastewater.
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- 2024
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180. Biogenic Phosphonate Utilization by Globally Distributed Diatom Thalassiosira pseudonana
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Huilin Shu, Yuan Shen, Hongwei Wang, Xueqiong Sun, Jian Ma, and Xin Lin
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phosphonate ,bioavailability ,diatom ,2-AEP ,2-AP3 ,Biology (General) ,QH301-705.5 - Abstract
Phosphonates are a class of organic phosphorus (P) compounds that contribute ~25% of dissolved organic P. Recent studies reveal the important role of phosphonates mediated by prokaryotes in the marine P redox cycle. However, its bioavailability by eukaryotic phytoplankton is under debate. 2-Aminoethylphosphonic acid (2-AEP) and 2-amino-3-phosphonopropionic acid (2-AP3) are two biogenic phosphonates in the marine environment. Here, Thalassiosira pseudonana, a common diatom species in the ocean, is able to recover growth from P starvation when provided with 2-AEP and 2-AP3. Moreover, 2-AEP cultures exhibited a more similar growth rate at 12 °C than at 25 °C when compared with inorganic P cultures. The cellular stoichiometry of 2-AEP groups was further determined, the values of which are in-between the P-depleted and DIP-replete cultures. This study provides evidence that biogenic phosphonates could be adopted as alternative P sources to support diatom growth and may provide physiological adaptation.
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- 2024
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181. Mineralogy and a New Fertility Index of Alunite in the Fanshan Lithocap, Luzong Basin, Anhui Province, China
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Xuanxuan Li, Qingling Xiao, Xin Lin, Shuangfei Li, and Mingying Tang
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alunite ,lithocap ,FT-IR ,DTA ,prospecting ,Mineralogy ,QE351-399.2 - Abstract
Alunite is used as a representative mineral for indicating deposits in lithocaps, and lithocaps are generally related to the porphyry–(high-sulfidation) epithermal mineralization system. The study of alunite is of theoretical and exploration significance for prospecting potential underlying porphyry and epithermal deposits. Studies on alunite geochemistry have made breakthroughs, but there is little research on alunite mineralogy, for example, using scanning electron microscopy (SEM) images, differential thermal analysis (DTA), and Fourier-transform infrared spectroscopy (FT-IR). This study mainly focuses on alunite micromorphological characteristics, weight loss changes with temperature, and ionic group structure, aiming to identify the relationship between these features and indications for prospecting. The Fanshan lithocap is located in the northwest part of the Luzong basin, Anhui province of China, and it can potentially be used for exploring porphyry and epithermal deposits. Fanshan alunite is formed in two stages with three types of alunite. IA alunite is formed in the early hydrothermal stage and replaces felsic minerals in the Zhuanqiao Formation, IB alunite is formed in the later hydrothermal stage and fills in open spaces with bladed particles, and II alunite is the product of pyrite oxidation and reaction with other minerals in the supergene stage. Alunite electron microprobe data and energy-dispersive spectroscopy data further confirm temperature decreases with hydrothermal evolution, and the presence of a high-sulfidation epithermal system in the Luzong basin. Aside from the forming environment, SWIR, and geochemistry of alunite, there are other indication indexes; for example, the larger peak values at 3480 cm−1 and smaller peak values at 1080 cm−1 in FT-IR spectra and the deeper exothermic valleys at 750 °C and steeper weight loss slopes in the DTA curve suggest a favorable formation environment for alunite and provide valuable indications for deposit exploration and assessments of mineralization potential.
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- 2024
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182. UAV-Assisted Image Acquisition: 3D UAV Trajectory Design and Camera Control
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Tang, Xiao-Wei, Zhang, Shuowen, You, Changsheng, Huang, Xin-Lin, and Zhang, Rui
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Computer Science - Multimedia - Abstract
In this paper, we consider a new unmanned aerial vehicle (UAV)-assisted oblique image acquisition system where a UAV is dispatched to take images of multiple ground targets (GTs). To study the three-dimensional (3D) UAV trajectory design for image acquisition, we first propose a novel UAV-assisted oblique photography model, which characterizes the image resolution with respect to the UAV's 3D image-taking location. Then, we formulate a 3D UAV trajectory optimization problem to minimize the UAV's traveling distance subject to the image resolution constraints. The formulated problem is shown to be equivalent to a modified 3D traveling salesman problem with neighbourhoods, which is NP-hard in general. To tackle this difficult problem, we propose an iterative algorithm to obtain a high-quality suboptimal solution efficiently, by alternately optimizing the UAV's 3D image-taking waypoints and its visiting order for the GTs. Numerical results show that the proposed algorithm significantly reduces the UAV's traveling distance as compared to various benchmark schemes, while meeting the image resolution requirement., Comment: This paper has been accepted by IEEE VTC2022-Fall and will appear soon!
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- 2020
183. Re-operation for incidental gallbladder carcinoma: When is the optimal time interval?
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Fei Liu, Qiao Huang, Yi-Xin Lin, and Fu-Yu Li
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Surgery ,RD1-811 - Published
- 2024
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184. Temperature-Dependent Thermal Conductivity and Absorption Coefficient Identification of Quartz Window up to 1100 K
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Shi, Yu, Chen, Xue, Sun, Chuang, and Xia, Xin-Lin
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- 2023
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185. Dietary sodium/potassium intake and cognitive impairment in older patients with hypertension: Data from NHANES 2011–2014
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Chengkun Kou, Xu Zhao, Xin Fan, Xin Lin, Qiongying Wang, and Jing Yu
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cognition ,dietary sodium ,hypertension ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract This study aimed to assess the relationship between dietary sodium/potassium intake and cognition in elderly individuals with hypertension. We designed a cross‐sectional study based on the 2011–2014 National Health and Nutrition Examination Survey (NHANES) 2011–2014. A multivariable‐logistic regression analysis was performed to analyze the relationship between sodium/potassium intake and cognitive impairment. Restricted cubic spline (RCS) based on regression analysis to assess the nonlinear dose‐response relationship between dietary sodium intake and cognitive performance. Out of the 2276 participants included in this study, 1670 patients had hypertension. Compared with the lowest quartile of dietary sodium intake, the lowest weighted odds ratio of cognitive impairment in DSST was observed in Q4 (OR = 0.45, 0.29–0.70), and a similar trend was observed in AFT (OR = 0.34, 0.18–0.65). After adjusting the covariates, the lowest weighted multivariable‐adjusted OR of cognitive impairment in DSST were also observed in Q4 (OR = 0.47, 0.26‐0.84) compared with the lowest quartile of dietary sodium intake. The RCS results showed that dietary sodium intake was U‐shaped and associated with the risk of cognitive impairment in the DSST (Pnon–linearity = 0.0067). In addition, no significant association was observed between dietary potassium intake and different dimensions of cognitive performance. In conclusion, excessively high and low low dietary sodium were associated with impairment of specific processing speed, sustained attention, and working memory for elderly patients with hypertension in the United States. However, no association was observed between dietary potassium intake and cognition.
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- 2023
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186. Transcriptome sequencing and miRNA-mRNA network construction in exosome of macrophage M2 in stomach adenocarcinoma
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Dun Pan, Zhipeng Li, Xin Lin, and Liangqing Li
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Stomach adenocarcinoma ,Exosome ,Macrophage M2 ,RNA sequencing ,miRNA ,mRNA ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Stomach adenocarcinoma (STAD) is the most common histological type of gastric cancer (GC). Macrophages are an essential part of the tumor microenvironment. We attempted to search for potential molecular markers associated with macrophages, which might be helpful for STAD diagnosis and treatment. Methods Firstly, exosome in macrophages was extracted for RNA sequencing to identify differentially expressed microRNAs (miRNAs) (DEmiRNAs). Then, DEmiRNAs and differentially expressed mRNAs (DEmRNAs) were screened in the Cancer Genome Atlas (TCGA) database. The miRNAs related to macrophage M2 polarization were obtained by intersecting the DEmiRNAs obtained from the sequencing data and TCGA data. Using the Pearson correlation coefficient method, the mRNAs significantly related to macrophage M2 were screened out, followed by construction of the macrophage M2-miRNA-mRNA network. Subsequently, real-time-polymerase chain reaction (RT-PCR) and online datasets were applied to validate the expression of DEmiRNAs and DEmRNAs. Results A total of 6 DEmiRNAs were identified in RNA sequencing; 59 DEmiRNAs and 1838 DEmRNAs were identified in TCGA database. Among which, a common miRNA (hsa-miR-133a-3p) associated with the M2 polarization of macrophages was identified. Fifteen common mRNAs were obtained between DEmRNAs and mRNAs targeted by DEmiRNAs. Eventually, a core macrophage M2-1 down-regulated miRNA-7 and up-regulated mRNAs network was constructed, including hsa-miR-133a-3p, SLC39A1, TTYH3, HAVCR2, TPM3, XPO1, POU2F1, and MMP14. The expression of miRNA and mRNAs was in line with the validation results of RT-PCR and online datasets. Conclusion In this study, the screening of biomarkers in exosome of macrophage M2 may contribute to the prognosis of STAD patients.
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- 2023
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187. Young Sca-1+ bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization
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Yuan Wang, Wan-yun Qin, Qi Wang, Xin-na Liu, Xiang-hui Li, Xin-qi Ye, Ying Bai, Yan Zhang, Pan Liu, Xin-lin Wang, Yu-hang Zhou, Hui-ping Yuan, and Zheng-bo Shao
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Exosomes ,Bone marrow Sca-1+ cell ,Ischemia/reperfusion injury ,miR-150-5p ,MEKK3 ,Biotechnology ,TP248.13-248.65 ,Medical technology ,R855-855.5 - Abstract
Abstract Background Polarization of microglia, the resident retinal immune cells, plays important roles in mediating both injury and repair responses post-retinal ischemia–reperfusion (I/R) injury, which is one of the main pathological mechanisms behind ganglion cell apoptosis. Aging could perturb microglial balances, resulting in lowered post-I/R retinal repair. Young bone marrow (BM) stem cell antigen 1-positive (Sca-1+) cells have been demonstrated to have higher reparative capabilities post-I/R retinal injury when transplanted into old mice, where they were able to home and differentiate into retinal microglia. Methods Exosomes were enriched from young Sca-1+ or Sca-1− cells, and injected into the vitreous humor of old mice post-retinal I/R. Bioinformatics analyses, including miRNA sequencing, was used to analyze exosome contents, which was confirmed by RT-qPCR. Western blot was then performed to examine expression levels of inflammatory factors and underlying signaling pathway proteins, while immunofluorescence staining was used to examine the extent of pro-inflammatory M1 microglial polarization. Fluoro-Gold labelling was then utilized to identify viable ganglion cells, while H&E staining was used to examine retinal morphology post-I/R and exosome treatment. Results Sca-1+ exosome-injected mice yielded better visual functional preservation and lowered inflammatory factors, compared to Sca-1−, at days 1, 3, and 7 days post-I/R. miRNA sequencing found that Sca-1+ exosomes had higher miR-150-5p levels, compared to Sca-1− exosomes, which was confirmed by RT-qPCR. Mechanistic analysis found that miR-150-5p from Sca-1+ exosomes repressed the mitogen-activated protein kinase kinase kinase 3 (MEKK3)/JNK/c-Jun axis, leading to IL-6 and TNF-α downregulation, and subsequently reduced microglial polarization, all of which contributes to reduced ganglion cell apoptosis and preservation of proper retinal morphology. Conclusion This study elucidates a potential new therapeutic approach for neuroprotection against I/R injury, via delivering miR-150-5p-enriched Sca-1+ exosomes, which targets the miR-150-5p/MEKK3/JNK/c-Jun axis, thereby serving as a cell-free remedy for treating retinal I/R injury and preserving visual functioning.
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- 2023
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188. Numerical simulation study on the impact of high intensity mining activities on groundwater
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Qingxu LYU, Junzhen DI, Guo LI, and Xin LIN
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coal mining ,numerical simulation of groundwater ,groundwater flow field ,gms ,Mining engineering. Metallurgy ,TN1-997 - Abstract
In order to explore the impact of high-intensity mining activities on groundwater, a mine field in Shendong Coal Mine Area of Inner Mongolia is selected as the research object. This mine is characterized by a large proportion of mining area on the plane, a large mining size in space and a fast mining speed in time. Based on the collection of relevant hydrometeorological and survey data, the Groundwater Modeling System numerical simulation software was used to establish a Groundwater flow model in accordance with the hydrogeological conditions of the study area. The Groundwater level and flow field under the influence of mining in the study area in the next 10 years were predicted and analyzed. The equilibrium state of groundwater is also analyzed. The results show that the disturbance of Zhiluo group Aquifer is most affected by high intensity mining, and several water level drop funnels are formed in the mining area. The water level in the center of the drop funnels increases from 105 m at the end of the first year to 351 m at the end of the tenth year, and the overall groundwater level and runoff conditions of this layer are changed. The influence of high intensity mining on the aquifer of Zhidan Group is small, and the water flow field changes only in the local position above the mine. In 10 years, the water level at the mining center decreases from 20 m to 116 m. According to the water balance analysis, the total groundwater recharge is 357 589.74 m3/d, and the total excretion is 357 563.62 m3/d, with an error of 0.0073%. Rainfall infiltration is the main recharge source in the study area, accounting for 51.90%, followed by river recharge, accounting for 45.21%. River drainage was the main way of discharge, accounting for 78.24%, followed by phreatic evaporation, accounting for 9.82%, and mine drainage, accounting for 4.52%. The recharge and discharge of the Zhidan group and Zhiluo group account for 12.0% and 5.7% of the total mean measurement in the region, respectively, and mine drainage is the main discharge mode of the Zhiluo Formation aquifers, accounting for 71.3%. The research results provide some basis for the protection of production safety and sustainable development in mining areas.
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- 2023
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189. Effects of Acute Freshwater Stress on Tissue Structure of Gill, Heart, Spleen and Liver of Juvenile Eleutheronema tetradactylum
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Shuyu XU, Youjun OU, Jiufu WEN, Xin LIN, and Jia'er LI
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eleutheronema tetradactylum ,freshwater stress ,gill ,heart ,spleen ,liver ,tissue structure ,Agriculture - Abstract
【Objective】To investigate the effects of acute fresh water stress on the morphological changes of gill, heart, spleen and liver of juvenile Eleutheronema tetradactylum, in order to provide reference for exploring low salinity culture techniques and selection of good breeds.【Methods】Juvenile E. tetradactylum, temporarily reared at salinity 9, with an average overall length of 2.31 cm and an average body mass of 3.81 g, were placed directly into an aquarium with a salinity of 0. Live samples were taken at 2, 6, 12, 24, 48 and 72 h. Histological methods were used to study the gill, heart, spleen and liver structures of juvenile E. tetradactylum under different durations of acute fresh water stress.【Results】In juvenile E. tetradactylum, the length of the gill lamellae tended to increase gradually, the spacing of the gill lamellae increased and then decreased, the width of the gill lamellae decreased and then increased, and the number of mitochondria-rich cells continued to increase when exposed to acute freshwater stress. The number of mitochondria-rich cells continued to increase. The size of the myocardial transverse muscle, the size of the myocardial cell gap and the size of the interstitial vessels all showed a trend of increasing and then decreasing. The peak of myocardial transverse muscle size was 12 h, and the peak of myocardial interstitial and interstitial vessel size was 24 h. The white marrow area and marginal zone area gradually increased from 0 to 24 h, and the colour of melanin macrophages also gradually deepened, reaching a peak at 24 h and then gradually decreasing. 72 h later, the red marrow, marginal zone, white marrow and melanin macrophages were roughly restored to the level of the control group. In the control group, the hepatocytes were large, polyhedral, with rounded nuclei and centrally located, and some hepatocytes had 2-3 nuclei; the hepatic plate was clearly defined; the hepatic blood sinusoids were normally distributed among the hepatocytes. During 24h of stress, the hepatic plate structure was gradually blurred and the gap between the hepatic blood sinusoids was gradually widened, reaching a peak at 24h of stress; during 24-72h of stress, the hepatic plate structure gradually regained clarity, the gap between the hepatic blood sinusoids was gradually reduced and some nuclei lost their intrinsic morphology.【Conclusion】Some tissues of juvenile E. tetradactylum showed stress reaction during 0-24 h, but adapted to the low-salt environment after 24 h. However, there were still some tissues that had difficulty in recovering to the control level after being subjected to low salt stress. This indicates that juvenile E. tetradactylum have some ability to adapt to low salt stress.
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- 2023
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190. 生物柴油低温过滤阻塞性能的影响因素及评价方法Influencing factors and evaluation methods of low-temperature filtration blocking performance of biodiesel
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夏鑫,蔺建民,李妍,杨鹤,陶志平,丁晓亮 XIA Xin, LIN Jianmin, LI Yan, YANG He, TAO Zhiping, DING Xiaoliang
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生物柴油;低温过滤阻塞性能;影响因素;冷浸过滤试验法 ,biodiesel ,low-temperature filtration blocking performance ,influencing factor ,cold soak filtration test ,Oils, fats, and waxes ,TP670-699 - Abstract
生物柴油低温过滤阻塞性能差是阻碍生物柴油发展的重要原因之一。为了加强生物柴油行业规范化,促进生物柴油产业健康发展,综述了生物柴油低温过滤阻塞性能的影响因素和评价方法,并根据不同影响因素提出了建议。生物柴油中饱和脂肪酸甲酯、脂肪酸甘油酯、游离甘油、甾醇糖苷均会影响生物柴油低温过滤阻塞性能。可通过调变生物柴油分子结构,添加流动性改进剂和冷冻分离饱和脂肪酸甲酯等方法,减少饱和脂肪酸甲酯对生物柴油低温过滤阻塞性能的负面影响。ASTM D7501是评价生物柴油低温过滤阻塞性能的有效方法。在ASTM D7501基础上,制定的适用于我国生物柴油低温过滤阻塞性能评价的试验方法,对于促进我国生物柴油产品品质提升具有现实意义。 Poor biodiesel low-temperature filtration blocking performance is one of the important reasons hindering the development of biodiesel. In order to strengthen the standardization of biodiesel industry and promote the healthy development of biodiesel industry, the influencing factors and evaluation methods of low-temperature filtration blocking performance of biodiesel were reviewed, and suggestions were made according to different influencing factors. Saturated fatty acid methyl esters, fatty acid glycerides, free glycerol, sterol glycosides in biodiesel can affect the low-temperature filtration blocking performance of biodiesel. The negative effect of saturated fatty acid methyl esters on the low-temperature filtration blocking performance of biodiesel can be reduced by modifying the molecular structure of biodiesel, adding flow improver and freezing separation of saturated fatty acid methyl esters. ASTM D7501 is an effective method to evaluate the low-temperature filtration blocking performance of biodiesel. The standard method of evaluating the low-temperature filtration blocking performance of biodiesel in China developed on the basis of ASTM D7501, is of practical significance to promote the quality improvement of biodiesel products in China.
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- 2023
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191. Association between chronic pain and risk of incident dementia: findings from a prospective cohort
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Jing Tian, Graeme Jones, Xin Lin, Yuan Zhou, Anna King, James Vickers, and Feng Pan
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Chronic pain ,Musculoskeletal pain ,Multisite pain ,Incidence ,Dementia ,Medicine - Abstract
Abstract Background Chronic musculoskeletal pain has been linked to dementia; however, chronic pain typically occurs in multiple sites; therefore, this study was to investigate whether greater number of chronic pain sites is associated with a higher risk of dementia and its subtypes. Methods Participants (N = 356,383) in the UK Biobank who were dementia-free at baseline were included. Pain in the hip, knee, back, and neck/shoulder or ‘all over the body’ and its duration were assessed. Participants were categorised into six groups: no chronic pain; chronic pain in 1, 2, 3, and 4 sites, and ‘all over the body’. All-cause dementia and its subtypes were ascertained using hospital inpatient and death registry records. Cox regression was used to investigate the associations between the number of chronic pain sites and the incidence of all-cause dementia and its subtypes. Results Over a median follow-up of 13 years, 4959 participants developed dementia. After adjustment for sociodemographic, lifestyle, comorbidities, pain medications, psychological problems, and sleep factors, greater number of chronic pain sites was associated with an increased risk of incident all-cause dementia (hazard ratio [HR] = 1.08 per 1 site increase, 95% CI 1.05–1.11) and Alzheimer’s disease (AD) (HR = 1.09 per 1-site increase, 95% CI 1.04–1.13) in a dose–response manner but not vascular and frontotemporal dementia. No significant association was found between the number of chronic pain sites and the risk of incident all-cause dementia among a subsample that underwent a fluid intelligence test. Conclusions Greater number of chronic pain sites was associated with an increased risk of incident all-cause dementia and AD, suggesting that chronic pain in multiple sites may contribute to individuals’ dementia risk and is an underestimated risk factor for dementia.
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- 2023
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192. Effect of arc oscillation on porosity and mechanical properties of 2319 aluminum alloy fabricated by CMT-wire arc additive manufacturing
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Yuhan Wei, Fencheng Liu, Fenggang Liu, Dong Yu, Qifan You, Chunping Huang, Zhitai Wang, Wugui Jiang, Xin Lin, and Xiaoan Hu
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Wire arc additive manufacturing ,Arc oscillation: 2319 aluminum alloy ,Porosity ,Mechanical properties ,Mining engineering. Metallurgy ,TN1-997 - Abstract
In this paper, arc oscillation is applied in the fabrication of 2319 aluminum alloy samples by cold metal transition wire arc additive manufacturing process (CMT-WAAM). The porosity, microstructure and mechanical properties of 2319 aluminum alloy under different arc oscillation patterns were discussed. The results showed that the stirring of arc oscillation can influence the molten pool shape and improve the fluidity, change the thermal distribution and the growth direction of columnar crystal. Arc oscillation has a obvious effect on reducing the grain size and proportion of pores. After using the spiral arc oscillation pattern and asymmetrical trapezoid arc oscillation pattern, the volume fraction of pores reduced from 2.64% to 1.09% and 1.22%, and the size of pores was mainly smaller than 40 μm, respectively. The tensile strength in vertical direction and plasticity were improved with arc oscillation, but its effect on the horizontal tensile strength was not noticeable. After solid solution-aging treatment, the tensile strength of the sample with spiral arc oscillation pattern increased to 277 MPa, with a cross-section reduction of 3.6%.
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- 2023
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193. Cultural inclusion and corporate sustainability: evidence from food culture and corporate total factor productivity in China
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Guangfan Sun, Xin Lin, Junyi Chen, Nuo Xu, Ping Xiong, and Hanqi Li
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History of scholarship and learning. The humanities ,AZ20-999 ,Social Sciences - Abstract
Abstract This article constructed a food taste deviation index using text analysis based on food culture as a measure of cultural inclusion. Cultural inclusion was related to corporate total factor productivity, aiming to investigate whether the cultural inclusion affects corporate sustainability. The findings showed uneven distribution of cultural inclusion in various areas of China, contributing to the unbalanced sustainable development of firms in different regions, as reflected by the higher total factor productivity of firms located in regions with higher cultural inclusion. A test using mountainous undulation as an instrumental variable verified the causal relationship between cultural inclusion and firm sustainability. Besides, a regression discontinuity design was employed to mitigate the impacts of the bidirectional causality. Moreover, a high level of cultural inclusion in top managers’ hometown significantly improved corporate sustainability, suggesting that executives can transmit cultural inclusion in society. In addition, firms in more inclusive regions are more motivated to increase their social responsibility to staff as a way to promote their total factor productivity, suggesting that cultural inclusion promotes firm sustainability by increasing firms’ care for staff. This article also found that cultural inclusion has heterogeneous effects across firms of different levels of industry competition, and different levels of analyst attention. The research reveals the impact of cultural inclusion on the real economy and help academics dissect the informal institutional reasons behind the sustainable development of firms in different geographies from a new perspective, contributing to the promotion of economic sustainability at the regional level and related policy formulation.
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- 2023
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194. Generator Versus Segmentor: Pseudo-healthy Synthesis
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Yunlong, Zhang, Chenxin, Li, Xin, Lin, Liyan, Sun, Yihong, Zhuang, Yue, Huang, Xinghao, Ding, Xiaoqing, Liu, and Yizhou, Yu
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Computer Science - Computer Vision and Pattern Recognition - Abstract
This paper investigates the problem of pseudo-healthy synthesis that is defined as synthesizing a subject-specific pathology-free image from a pathological one. Recent approaches based on Generative Adversarial Network (GAN) have been developed for this task. However, these methods will inevitably fall into the trade-off between preserving the subject-specific identity and generating healthy-like appearances. To overcome this challenge, we propose a novel adversarial training regime, Generator versus Segmentor (GVS), to alleviate this trade-off by a divide-and-conquer strategy. We further consider the deteriorating generalization performance of the segmentor throughout the training and develop a pixel-wise weighted loss by muting the well-transformed pixels to promote it. Moreover, we propose a new metric to measure how healthy the synthetic images look. The qualitative and quantitative experiments on the public dataset BraTS demonstrate that the proposed method outperforms the existing methods. Besides, we also certify the effectiveness of our method on datasets LiTS. Our implementation and pre-trained networks are publicly available at https://github.com/Au3C2/Generator-Versus-Segmentor., Comment: Accepted by MICCAI2021
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- 2020
195. QoE-Driven UAV-Enabled Pseudo-Analog Wireless Video Broadcast: A Joint Optimization of Power and Trajectory
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Tang, Xiao-Wei, Huang, Xin-Lin, and Hu, Fei
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Computer Science - Multimedia ,Electrical Engineering and Systems Science - Signal Processing - Abstract
The explosive demands for high quality mobile video services have caused heavy overload to the existing cellular networks. Although the small cell has been proposed to alleviate such a problem, the network operators may not be interested in deploying numerous base stations (BSs) due to expensive infrastructure construction and maintenance. The unmanned aerial vehicles (UAVs) can provide the low-cost and quick deployment, which can support high-quality line-of-sight communications and have become promising mobile BSs. In this paper, we propose a quality-of-experience (QoE)-driven UAV-enabled pseudo-analog wireless video broadcast scheme, which provides mobile video broadcast services for ground users (GUs). Due to limited energy available in UAV, the aim of the proposed scheme is to maximize the minimum peak signal-to-noise ratio (PSNR) of GUs' video reconstruction quality by jointly optimizing the transmission power allocation strategy and the UAV trajectory. Firstly, the reconstructed video quality at GUs is defined under the constraints of the UAV's total energy and motion mechanism, and the proposed scheme is formulated as a complex non-convex optimization problem. Then, the optimization problem is simplified to obtain a tractable suboptimal solution with the help of the block coordinate descent model and the successive convex approximation model. Finally, the experimental results are presented to show the effectiveness of the proposed scheme. Specifically, the proposed scheme can achieve over 1.6dB PSNR gains in terms of GUs' minimum PSNR, compared with the state-of-the-art schemes, e.g., DVB, SoftCast, and SharpCast.
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- 2020
196. Human-Perception-Oriented Pseudo Analog Video Transmissions with Deep Learning
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Tang, Xiao-Wei, Huang, Xin-Lin, Hu, Fei, and Shi, Qingjiang
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Computer Science - Multimedia ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
Recently, pseudo analog transmission has gained increasing attentions due to its ability to alleviate the cliff effect in video multicast scenarios. The existing pseudo analog systems are sorely optimized under the minimum mean squared error criterion without taking the perceptual video quality into consideration. In this paper, we propose a human-perception-based pseudo analog video transmission system named ROIC-Cast, which aims to intelligently enhance the transmission quality of the region-of-interest (ROI) parts. Firstly, the classic deep learning based saliency detection algorithm is adopted to decompose the continuous video sequences into ROI and non-ROI blocks. Secondly, an effective compression method is used to reduce the data amount of side information generated by the ROI extraction module. Then, the power allocation scheme is formulated as a convex problem, and the optimal transmission power for both ROI and non-ROI blocks is derived in a closed form. Finally, the simulations are conducted to validate the proposed system by comparing with a few of existing systems, e.g., KMV-Cast, SoftCast, and DAC-RAN. The proposed ROIC-Cast can achieve over 4.1dB peak signal- to-noise ratio gains of ROI compared with other systems, given the channel signal-to-noise ratio as -5dB, 0dB, 5dB, and 10dB, respectively. This significant performance improvement is due to the automatic ROI extraction, high-efficiency data compression as well as adaptive power allocation.
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- 2020
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197. A Design of SDR-based Pseudo-Analog Wireless Video Transmission System
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Tang, Xiao-Wei and Huang, Xin-Lin
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Electrical Engineering and Systems Science - Signal Processing ,Computer Science - Multimedia ,Computer Science - Networking and Internet Architecture - Abstract
The pseudo-analog wireless video transmission technology can improve the effectiveness, reliability, and robustness of the conventional digital system in video broadcast scenarios. Although some prototypes of IEEE 802.11 series have been developed for researchers to do simulations and experiments, they are usually expensive and provide very limited access to the physical layer. More importantly, these prototypes cannot be used to verify the correctness of the new proposed pseudo-analog wireless video transmission algorithms directly due to limited modulation modes they can support. In this paper, we present a novel design of software radio platform (SDR)-based pseudo-analog wireless video transceiver which is completely transparent and allows users to learn all the implementation details. Firstly, we prove that the analog method can also achieve the optimal performance as the digital method from the perspective of the rate-distortion theory. Then, we describe the two hardware implementation difficulties existed in the designing process including the data format modification and the non-linear distortion. Next, we introduce the implementation details of the designed transceiver. Finally, we analyze the performance of the designed transceiver. Specifically, the results show that the designed system can work effectively in both simulations and experiments.
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- 2020
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198. Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway
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Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, and Liyu Xu
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asthma ,umbilical cord blood mesenchymal stem cells ,Hedgehog pathway ,inflammation ,Biology (General) ,QH301-705.5 - Abstract
This study aimed to explore the role and mechanism of umbilical cord mesenchymal stem cells (UCMSCs) in regulating inflammation of bronchial epithelial cells. Transforming growth factor beta-1 (TGF-β1) was used to induce inflammation in human bronchial epithelial cells. Cell proliferation was detected through CCK8 and cell apoptosis was detected by Annexin V and propidium iodide double staining. E-cadherin and α-smooth muscle actin (α-SMA) were detected by immunofluorescence, and tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) in culture medium supernatant were detected by ELISA. The expression of E-cadherin, α-SMA, Sonic hedgehog (Shh), Gli1 and Snail was detected by Western blot analysis. Compared with the control group, bronchial epithelial cells treated with TGF-β1 showed significantly decreased proliferation, increased apoptosis, increased secretion of TNF-α and IL-6, increased expression of α-SMA, Shh, Gli1 and Snail and decreased E-cadherin expression. However, co-culture with UCMSCs inhibited TGF-β1-induced changes in human bronchial epithelial cell proliferation, apoptosis, secretion of TNF-α and IL-6 and activation of the Hedgehog pathway. In conclusion, UCMSCs have protective effects on TGF-β1-induced inflammation in human bronchial epithelial cells by regulating the Hedgehog pathway.
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- 2023
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199. DESIGN AND EXPERIMENT OF A COMBINED TYPE SPATIALLY LAYERED PROPORTIONAL FERTILIZATION DEVICE
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Hang Li, Xin Lin, Jin He, Caiyun Lu, and Wenchao Yang
- Subjects
wheat ,layered fertilization device ,structure optimization ,element distinct method ,response surface experiment ,Agriculture (General) ,S1-972 - Abstract
ABSTRACT To solve the problems of low efficiency, poor fertilizer application, and low fertilizer utilization rate of existing wheat layered fertilization devices (LFD). This paper proposed a layered fertilization mode combining shallow fertilizer application based on rotary tillage and middle/deep fertilizer application of layered fertilizer shovel (LFS), and designed a combined spatial layered fertilization device with a fixed proportion. A discrete element simulation model consisting of soil, LFS and fertilizer was established. Taking the variation coefficients of fertilization amount as the evaluation indicator and changing the sidewall deflection angle, rear inclination angle, upper channel length of LFS, a three-factor three-level quadratic rotational orthogonal experiment was carried out. The optimal parameter combination was obtained: the deflection angle was 9.5°, the inclination angle was 57°, and the channel length was 280 mm. The corresponding variation coefficients of fertilizer application depth were 4.55%, 8.44%, and 6.93% while working stably under the optimal combination, which is consistent with the simulation results. The results showed that LFD can apply fertilizer underground in three layers: 0~10, 15, and 20 cm, with the proportion of shallow, middle, and deep fertilizers being 30%, 35%, and 35%, which can meet the agronomic requirements for winter wheat growth.
- Published
- 2023
- Full Text
- View/download PDF
200. High-resolution assessment of coal mining methane emissions by satellite in Shanxi, China
- Author
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Shushi Peng, Clément Giron, Gang Liu, Alexandre d’Aspremont, Antoine Benoit, Thomas Lauvaux, Xin Lin, Hugo de Almeida Rodrigues, Marielle Saunois, and Philippe Ciais
- Subjects
Atmospheric science ,Atmospheric chemistry ,Atmospheric observation ,Science - Abstract
Summary: Accurate assessment of coal mine methane (CMM) emissions is a prerequisite for defining baselines and assessing the effectiveness of mitigation measures. Such an endeavor is jeopardized, however, by large uncertainties in current CMM estimates. Here, we assimilated atmospheric methane column concentrations observed by the TROPOMI space borne instrument in a high-resolution regional inversion to estimate CMM emissions in Shanxi, a province representing 15% of the global coal production. The emissions are estimated to be 8.5 ± 0.6 and 8.6 ± 0.6 Tg CH4 yr−1 in 2019 and 2020, respectively, close to upper bound of current bottom-up estimates. Data from more than a thousand of individual mines indicate that our estimated emission factors increase significantly with coal mining depth at prefecture level, suggesting that ongoing deeper mining will increase CMM emission intensity. Our results show robustness of estimating CMM emissions utilizing TROPOMI images and highlight potential of monitoring methane leakages and emissions from satellites.
- Published
- 2023
- Full Text
- View/download PDF
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