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2,307 results on '"Xie, Ke"'

153. On the modelling and experimental study of CO2laser ablation on resin-bond diamond grinding wheels: Understanding the effect of processing parameters on the time-dependent temperature field

Author

Xie, Ke Ge, Rushworth, Adam George Antrum, Chen, Hao, and Li, Jinyi

Abstract

The need for the precise dressing of diamond abrasive tools by laser has been highly emphasised but determining controllable material removal strategies for precise laser processing remains challenging due to the complex interaction between the composite abrasive materials and the laser beam. To fill this gap, an innovative simulation model pertaining to the laser ablation process has been devised to study the temporal evolution of the temperature field distribution within the ablation zone during processing, alongside monitoring the alterations in ablation depth along the feed direction. The laser spot focus size and the cross-section laser energy intensity distribution along the beam propagation direction, as well as the dynamic, unsteady-state heat conduction and convection, are considered in this model. Based on the simulation results, the ablation law regarding temperature field distribution and ablation depth variation with laser power and feed rate is revealed. It is shown that the laser power has a limited impact on the shape of temperature field distribution, but the core temperature of the heat-affected zone increases with laser power. The feed rate affects mainly the distribution range of the heat-affected zone and the range shrinks with the feed rate. It is revealed that a higher laser power with a matched higher feed rate is highly expected to optimise the ablation. Finally, the simulation results are experimentally validated and reasonable agreements are obtained. The work provides numerical and experimental evidence to evaluate the time-dependent temperature distribution during the laser ablation process.

Published
2024
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154. Sector Bound-Dependent Matrix-Separation-Based Inequality and its Application to Stability Analysis of Discrete-Time Delayed Genetic Regulatory Networks

Author

Xie, Ke-You, Zhang, Chuan-Ke, Lee, Sangmoon, Liu, Yajuan, and Zhai, Chao

Abstract

In this brief, a class of sector bound-dependent matrix-separation-based inequality is proposed that can utilize the properties of nonlinear functions to overcome the weaknesses of existing estimation methods. Then, an expanded class of Lyapunov–Krasovskii functional is constructed to include some integral terms of the sector constraint of nonlinear functions. By applying the improved inequality, the stability criterion of genetic regulatory networks (GRNs) with stochastic perturbations and time-varying delay is established. The validity of presented criterion and the advancement of proposed method are analysed based on two examples.

Published
2024
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164. Cellular senescence in cancer: molecular mechanisms and therapeutic targets.

Author

Jin, Ping, Duan, Xirui, Li, Lei, Zhou, Ping, Zou, Cheng‐Gang, and Xie, Ke

Subjects
CELLULAR aging, GENE targeting, DRUG target, IMMUNOSENESCENCE, AGING, BIOLOGY, CELL communication
Abstract

Aging exhibits several hallmarks in common with cancer, such as cellular senescence, dysbiosis, inflammation, genomic instability, and epigenetic changes. In recent decades, research into the role of cellular senescence on tumor progression has received widespread attention. While how senescence limits the course of cancer is well established, senescence has also been found to promote certain malignant phenotypes. The tumor‐promoting effect of senescence is mainly elicited by a senescence‐associated secretory phenotype, which facilitates the interaction of senescent tumor cells with their surroundings. Targeting senescent cells therefore offers a promising technique for cancer therapy. Drugs that pharmacologically restore the normal function of senescent cells or eliminate them would assist in reestablishing homeostasis of cell signaling. Here, we describe cell senescence, its occurrence, phenotype, and impact on tumor biology. A "one‐two‐punch" therapeutic strategy in which cancer cell senescence is first induced, followed by the use of senotherapeutics for eliminating the senescent cells is introduced. The advances in the application of senotherapeutics for targeting senescent cells to assist cancer treatment are outlined, with an emphasis on drug categories, and the strategies for their screening, design, and efficient targeting. This work will foster a thorough comprehension and encourage additional research within this field. [ABSTRACT FROM AUTHOR]

Published
2024
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165. Body Freedom Flutter Investigation Using Different Commercial Softwares

Author

Xie, Ke, Gu, Yingsong, Liu, Jihai, Shi, Pengtao, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martin, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, and Zhang, Xinguo, editor

Published
2019
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166. Flutter Modeling, Analysis and Test for Blended-Wing-Body Flying Wing

Author

Liu, Jihai, Gu, Yingsong, Xie, Ke, Shi, Pengtao, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martin, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, and Zhang, Xinguo, editor

Published
2019
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180. Controlling the Supramolecular Architecture Enables High Lithium Cationic Conductivity and High Electrochemical Stability for Solid Polymer Electrolytes

Author

Xie, Ke, primary, Fu, Qiang, additional, Chen, Fangfang, additional, Zhu, Haijin, additional, Wang, Xiaoen, additional, Huang, Gongyue, additional, Zhan, Hualin, additional, Liang, Qinghua, additional, Doherty, Cara M., additional, Wang, Dawei, additional, Qiao, Greg G., additional, and Li, Dan, additional

Published
2024
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188. On the Accuracy of Hyper-local Geotagging of Social Media Content

Author

Flatow, David, Naaman, Mor, Xie, Ke Eddie, Volkovich, Yana, and Kanza, Yaron

Subjects
Computer Science - Information Retrieval, Computer Science - Social and Information Networks
Abstract

Social media users share billions of items per year, only a small fraction of which is geotagged. We present a data- driven approach for identifying non-geotagged content items that can be associated with a hyper-local geographic area by modeling the location distributions of hyper-local n-grams that appear in the text. We explore the trade-off between accuracy, precision and coverage of this method. Further, we explore differences across content received from multiple platforms and devices, and show, for example, that content shared via different sources and applications produces significantly different geographic distributions, and that it is best to model and predict location for items according to their source. Our findings show the potential and the bounds of a data-driven approach to geotag short social media texts, and offer implications for all applications that use data-driven approaches to locate content., Comment: 10 pages

Published
2014

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