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Objective To investigate the situation of acute exacerbation readmission in elderly patients with Chronic Obstructive Pulmonary Disease (COPD) within 30 days, and to explore the influencing factors of readmission by structural equation model, so as to provide evidence for medical staff to take effective intervention measures. Methods Convenience sampling method was used to select 1120 elderly COPD patients from respiratory department of 13 general hospitals in Ningxia region from April 2019 to August 2020 for questionnaire survey. The participants completed the questionnaire containing general data questionnaire, Modified Medical Research Council (mMRC), Activities of Daily Living (ADL), the Geriatric Depression Scale (GDS), and COPD Assessment Test (CAT) scale. Results The readmission rate of acute exacerbation within 30 days in elderly COPD patients was 21.52%; The modified model fits well. Fitting results showed that seasonal factors, family rehabilitation, age factors and overall status were the direct influencing factors of acute exacerbation readmission in elderly COPD patients within 30 days. Smoking status is not only a direct factor for acute exacerbation of readmission within 30 days, but also an indirect effect through disease status; Disease status and chronic disease are not only direct factors for acute exacerbation of readmission within 30 days, but also indirectly through overall status. Conclusions The rate of acute exacerbation readmission within 30 days in elderly patients with COPD is high, While taking measures to prevent readmission based on direct influencing factors, attention should be paid to the interaction between factors.

Zn(II) and Cd(II) coordination polymers constructed from a new angular bis-pyridyl-bis-amide ligand and naphthalene-1,4-dicarboxylic acid (1,4-H2NDC), {[Zn2(L)(1,4-NDC)2]·2H2O} [L = 4,4′-oxybis(N-(pyridin-3-ylmethyl)benzamide)], 1, and {[Cd2(L)(1,4-NDC)2]·EtOH}, 2, have been solvothermally synthesized and structurally characterized by using single-crystal X-ray diffraction. While complex 1 displays a 2D double layer with the rare (46·64)-5 L4 topology, complex 2 shows a 3D framework with a new (4·5·6)(45·55·69·7·8) topology. Both complexes 1 and 2 display luminescence properties and 2 exhibits a high sensitivity toward the detection of Fe3+ ions with a Ksv value of 1.9 × 104 M−1. The quenching effect can most probably be ascribed to the interactions between the metal ions and the amide carbonyl oxygen atoms.

Herein, we report the synthesis of 2-spirocyclohexylindolines based on a Lewis acid mediated cyclization. This diastereoselective procedure provides the target structures in a straightforward way via dual activation.

Hydrothermal reactions of N,N′-di-3-pyridyladipoamide (L) with 1,2,4,5-benzenetetracarboxylic acid (1,2,4,5-H2btec) in water without and with NaOH afforded [Co(L)(1,2,4,5-btec)0.5]n, 1, and [Co(L)(...

The aim of this study was to investigate and analyze the content of 62 organic solvents in 110 liquid pesticide formulations. The study would provide a basis and reference for the promulgation of the relevant limits of organic solvents in pesticide formulations. The pesticide formulation was diluted with solvent, and the supernatant was filtered through a 0.22 μm membrane. After separation on a VF-1701 MS column, the analytes were detected by gas chromatography-mass spectrometry (GC-MS) in the selected ion monitoring (SIM) mode and quantified using the external standard method. A total of 110 pesticide formulation samples were analyzed. The results showed that 28 kinds of organic solvents, including xylene, N,N-dimethylformamide, methanol, methylbenzene, naphthalene, and ethylbenzene, were detected in 108 samples with content ranging from 0.07% to 77.23%. Among the 94 emulsifiable concentrate (EC) samples in which organic solvents had been detected, 76 violated the relevant state regulations on the limits of organic solvents in pesticide formulations. Liquid pesticide formulations generally contained high concentration of organic solvents and had great safety risks. We suggest that government departments should promulgate relevant standard on organic solvents in pesticide formulations as soon as possible.

One-pot solvothermal reactions of 2-aminopyridine, triethylorthoformate and sodium hydroxide with CuX (X = Br, and I) in dimethylformamide (DMF) and methanol (MeOH) afforded extended metal chains based on the linear tetracopper units, {[Cu4Br2(Dpyf)2]·DMF}n, 1, and [Cu4I2(Dpyf)2]n, 2, which were structurally identified by X-ray crystallography. Complexes 1 and 2 present closed-shell Cu(I)–Cu(I) interactions that are supported by formamidinate ligands, resulting in a face-to-side configuration and a face-to-face configuration, respectively, for the tetranuclear units. Complexes 1 and 2 represent the first example of one-dimensional (1D) coordination polymers that are based on linear tetracopper units. Moreover, complexes 1 and 2 can be regarded as copper(I) halide aggregates with the unique Cu4Br22+ and Cu4I22+ cations extending into a 1D zigzag chain and a looped chain, respectively. Complexes 1 and 2 show broad emissions at 570 and 549 nm, respectively, which can most probably be ascribed to 3d(Cu) → π* metal to ligand charge transfer. Reversible crystal-to-crystal transformation and luminescence change were observed for complex 1 upon solvent exchange, which can be regarded as a potential luminescent sensor for selective detection of water and methanol.

Solvothermal reactions of Cd(CH3COO)2 and 2,2′-(1,3-phenylene)-bis(N-pyridin-3-yl)acetamide (1,3-pbpa) with 1,3-phenylenediacetic acid (1,3-H2PDA), 4,4′-oxybis(benzoic acid) (4,4′-H2OBA) and 1,4-benzenedicarboxylic acid (1,4-H2BDC) afforded [Cd(1,3-pbpa)(1,3-PDA)]n, 1, [Cd(1,3-pbpa)(OBA)·2H2O]n, 2, and [Cd(1,3-pbpa)(1,4-BDC)(H2O)·EtOH·H2O]n, 3, respectively, which were structurally characterized as two-dimensional (2D) coordination polymers. Complexes 1 and 2 show the rare {84·122}{8}2-2,4L2 topology, whereas complex 3 adopts a new topology with a point symbol of {12}{4·125}{4}, which can be further simplified as the 44-sql topology and the 63-hcb topology, respectively. Desolvated product of 2 shows a moderate uptake of CO2 and a good selectivity over N2, which also exhibits a better H2 and CO2 sorption compared to the activated product of 1, indicating the effect of ligand type on the adsorption properties of 2D complexes with the 44-sql topology. Thermal gravimetric analysis (TGA) and the solid state luminescence properties of 1–3 have also been investigated.

Reactions of divalent metal salts with 4,4-oxybis(N-(pyridine-4-yl)-benzamide), L, and naphthalene-1,4-dicarboxylic acid (1,4-H2NDC) in various solvents gave [Zn(L)(1,4-NDC)·H2O]n, 1, [Cd(L)(1,4-NDC)(H2O)·MeOH]n, 2, and [Co(L)(1,4-NDC)(H2O)0.5·MeOH]n, 3, which have been structurally characterized. Complexes 1–3 show eight-fold interpenetrating frameworks with the dia topology, which exhibit porosities substantiated by CO2 adsorption, whereas 1 and 2 manifest stability in aqueous environments and show high selectivity toward sensing of mesitylene molecules and Fe3+ ions with low detection limits and good reusability up to five cycles.