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A recent randomized controlled trial (RCT) of a dual parent and trainer-delivered qigong massage intervention for young children with autism resulted in improvement of measures of autism as well as improvement of abnormal sensory responses and self-regulation. The RCT evaluated the effects of the parent-delivered component of the intervention. Forty-seven children were randomly assigned to treatment and wait-list control groups. Treatment group children received the parent-delivered program for 4 mo. Trained therapists provided parent training and support. Improvement was evaluated in two settings--preschool and home--by teachers (blind to group) and parents. Results showed that the parent-delivered program was effective in improving measures of autism (medium effect size) and sensory and self-regulatory responses (large effect size). Teacher data on measures of autism were confirmed by parent data. Results indicate that the parent-delivered component of the program provided effective early intervention for autism that was suitable for delivery at home.

Objective: To present a model for autism showing that impairment of sensory and self-regulation is the core deficit that underlies delays in social/language skills and abnormal behavior in autism; and to demonstrate the efficacy of a treatment for autism based on Chinese medicine., Methods: Children with autism under 6 years of age were assigned to treatment or wait-list conditions. A total of 130 children were treated and the results compared with 45 wait-list controls. Treatment is a tuina methodology directed at sensory impairment--Kai Qiao Tuina. The treatment was a five-month protocol that was implemented daily by trained parents via trained support staff. The effects of treatment on the main symptoms, autistic behavior, social/language delay, sensory and self-regulatory impairment, as well as on parenting stress, were observed and compared., Results: The treatment had a large effect size (P<0.0001) on measures of sensory and self-regulation. The evaluations done by pre-school teachers demonstrated improvement in the measures of autism (P<0.003), and were confirmed by evaluations done by parents (P<0.0001). There was a large decrease (P<0.0001) in parenting stress., Conclusions: Sensory and self-regulatory impairment is a main factor in the development and severity of autism. Treatment of young children with autism with Kai Qiao Tuina resulted in a decrease in sensory and self-regulatory impairment and a reduction in severity of measures of autism.

Currently, there are no published studies about the impact on students of a structured, breast-cancer-specific advocacy internship. Our goal was to provide the student perspective of participation in a national breast cancer advocacy conference in Washington, D.C. as part of an internship. Both qualitative and quantitative data were collected in three waves: 1 month before the training, during the training, and 1 month post-training. Four themes emerged: (1) empowerment, (2) connection with breast cancer patients and advocates, (3) learning outside the classroom, and (4) action through advocacy and civilian lobbying. This study found strong support for the internship model described here and is recommended for replication at other universities and institutions.

Background: A significant number of college women are at risk for alcohol-exposed pregnancies because the ages of the heaviest alcohol consumption is typically 18 through 21 years, and contraception may be used ineffectively or not at all. These risks call for greater prevention efforts., Objective: Collaboration between a higher education institution and a government health agency to reduce alcohol-exposed pregnancies in Oregon., Methods: Health professionals from the Fetal Alcohol Syndrome (FAS) Prevention Program of the Oregon Public Health Division presented current research and explained the mission of a Center for Disease Control (CDC) cooperative agreement to university students in a Health Communication course. The students then developed social marketing messages that targeted alcohol use and/or contraception behavior., Results: At the end of the course, the students presented their campaigns campus-wide, and to the state agency. Four of the theory-based messages are illustrated in this article., Conclusion: The students brought to the state FAS Program a specific range of knowledge, vocabulary and creative skills to create messages for young adults. University students reported benefits of becoming familiar with government agencies and working on "real-life" projects that had the potential to be used in community settings.

A stable surface-enhanced Raman scattering (SERS) substrate is developed through immobilization of gold sols onto aminated silica beads. The plasmon resonance is established by spacing of gold sols on the bead surface and remains stable over extended periods of time due to the large number of amine groups that provide stable anchoring of gold to the surface. Unlike planar supports, this substrate can be dispersed in a sample, providing high surface area for detection and efficient transport of analytes to its surface. This substrate can be used to detect the binding of a molecule to ligands on the silica surface, which avoids the stability limitations of thiol-bound ligands on gold. Chemical modification of the amine groups on the silica surface with benzoic anhydride could be readily detected in Raman scattering enhanced by the neighboring gold sols, with nearly the same sensitivity as benzylthiol bound directly to the gold surfaces. This result suggests future work involving the immobilization of other ligands through the residual amine groups to the silica, which could be used to selectively attract target analytes to the SERS-active surface.

Effective instructional and behavioral support strategies implemented by trained educators can help mitigate the academic and behavioral challenges associated with childhood brain injury. However, the training provided by university teacher preparation programs is clearly inadequate, a problem that cuts across the professions that work with school-aged students. Educators need training in methods validated for students with traumatic brain injury (TBI) and in adapting strategies validated for students with other disabilities. Almost 10 years after Ylvisaker and colleagues proposed a research and professional development agenda in the area of teacher training, students with TBI continue to be underserved and underidentified for educational supports. Effective staff development practices for educators must include training in evidence-based interventions, supervised practice with new skills, and continued mentoring, feedback, and consultation in the school setting. Two models currently in use-the TBI Consulting Team and BrainSTARS models-incorporate those features. Preliminary evidence suggests that these models help teachers feel more prepared and knowledgeable in working with students with TBI. Given the urgent needs of students with TBI, validating these promising practices should be a high priority for the field of pediatric brain injury.

To determine the effectiveness of a single, 1-minute bout of whole-body vibration (WBV) as a viable warm-up activity, 90 subjects (30 men; 60 women, mean age = 19 ± 1 years) were recruited and randomly assigned to either a nonvibration control group or 1 of 8 WBV treatments (4 frequencies × 2 AMplitudes). Subjects stood with the feet shoulder width apart and the knees flexed 10° on a Next Generation Power Plate for 1 minute with the frequency (30, 35, 40, or 50 Hz) and amplitude (2-4 or 4-6 mm) settings at the assigned levels. Before, 1, 5, 10, 15, 20, 25, and 30 minutes after the WBV or control treatment, subjects performed a series of countermovement vertical jumps (CMJs) measured using a Vertec vertical jump tester. Comparisons were made of changes in the countermovement vertical jump height (CMJH) over time and between groups, frequencies, and amplitudes using repeated measures analysis of variance (α ≤ 0.05). There were significant differences in CMJH over time (p = 0.008); however, these were similar for all groups, frequencies, and amplitudes (p > 0.88). Some athletes may benefit from using WBV as a warm-up activity, if the timing of WBV is optimized. The effect of WBV on performance is likely variable and minimal, with a small window of effectiveness. Gender differences were not examined, and the optimal duration, intensity, and postural position are still unclear and warrant further study.

Reliability of high-resolution accelerometery (HRA) and mechanomyography (MMG) was evaluated for the assessment of single-leg balance. Subjects (5M/5F, 25+/-3 yr; 169.4+/-11.7 cm; 79.0+/-16.9 kg) participated in fifteen (three randomized bouts of five repetitions) 15-s dominant leg stances. A single HRA was fixed superficial to L3/L4 segment to capture motions relative to the center-of-mass, and three-uniaxial accelerometers were fixed on the surface of the dominant leg correspondent to the vastus medialis (VM), vastus lateralis (VL), and soleus (SOL) muscles to record MMG. Triaxial signals from the HRA (s.r.=625 Hz) were streamed to a base station, simultaneously with MMG (s.r.=1000 Hz). Signals were sampled, recorded and later analyzed. HRAs were recorded in g's for vertical (VT), medial/lateral (ML), anterior/posterior (AP) directions, and resultant (RES) scalar. Intraclass correlation coefficients (ICC) were computed for each and Pearson's r was calculated for the relationships between MMG and HRA (alpha < or =0.05). Except for RES (ICC=0.36), all measures demonstrated moderately strong reliability (ICC=0.75, 0.73, 0.63, 0.87, 0.89, and 0.86 for VM, VL, SOL, VT, ML, and AP, respectively). HRA and MMG provide reliable information pertaining to balance, and may have application in evaluating postural control and stability., (Copyright (c) 2010 Elsevier Ltd. All rights reserved.)

This article examines socio-economic determinants and inequality of health care utilization in Ecuador. Despite health reform efforts in Latin America, drastic socio-economic inequalities persist across the region, including Ecuador. Almost a third of Ecuador's population lack regular access to health services, while more than two-thirds have no health insurance and insufficient resources to pay for health care services. Using Andersen's model of health care utilization behaviour, relevant variables were selected from the 2004 National Demographic and Maternal & Child Health Survey (ENDEMAIN) household survey. Four outcomes were assessed: use of preventive services, number of curative visits, hospitalization, and use of antiparasitic medicines. Adjusting for various predisposing, enabling and need factors, a significant negative relationship was found between household economic status (as measured by assets and consumption quintiles) and utilization of preventive and curative services. The same was true for use of antiparasitic medicines. Further, indigenous ethnicity was found to be a significant negative predictor of health care utilization, regardless of economic status. These socio-economic inequalities in the use of health care services suggest the need for health care reform in Ecuador to address these issues more systematically. It is necessary for public health authorities to move forward on a reform that will expand coverage, particularly to indigenous and low- and middle-income households.

Background: There are few studies that have analyzed the context of health care utilization, particularly in Latin America. This study examines the context of utilization of health services in Ecuador; focusing on the relationship between provision of services and use of both preventive and curative services., Methods: This study is cross-sectional and analyzes data from the 2004 National Demographic and Maternal & Child Health dataset. Provider variables come from the Ecuadorian System of Social Indicators (SIISE). Global Moran's I statistic is used to assess spatial autocorrelation of the provider variables. Multilevel modeling is used for the simultaneous analysis of provision of services at the province-level with use of services at the individual level., Results: Spatial analysis indicates no significant differences in the density of health care providers among Ecuadorian provinces. After adjusting for various predisposing, enabling, need factors and interaction terms, density of public practice health personnel was positively associated with use of preventive care, particularly among rural households. On the other hand, density of private practice physicians was positively associated with use of curative care, particularly among urban households., Conclusions: There are significant public/private, urban/rural gaps in provision of services in Ecuador; which in turn affect people's use of services. It is necessary to strengthen the public health care delivery system (which includes addressing distribution of health workers) and national health information systems. These efforts could improve access to health care, and inform the civil society and policymakers on the advances of health care reform.

The most common tools for assessing grief and loss focus on death-related loss. The Reactions to Loss Scale (RTL) broadens the scope of bereavement measures to include reactions to non-death losses. The population targeted by this measure, emerging adults (college students), commonly experiences a myriad of both death-related and non-death losses. The validity of the Reactions to Loss Scale (RTL) is investigated in 4 studies. Factor analysis of the 65-item RTL (N=564) identified 3 subscales, each demonstrating good reliability. In the first 3 studies, the RTL was found to be related to depression, anxiety, negative affect, and positive measures of satisfaction with life, happiness, and positive affect. In Study 4, prospective data was utilized to evaluate predictive validity. These data found that the RTL was predictive of longitudinal changes in negative affect, perceived social support, satisfaction with life, and positive feelings about the specific loss.

Autism is commonly associated with sensory and self-regulatory disturbances. This article presents a randomized controlled study evaluating the effect of a 5-month intervention directed toward improving sensory impairment, digestion, and sleep in 46 children with autism < age 6. The intervention, Qigong Sensory Training (QST), is a qigong massage intervention based in Chinese medicine. It is two-pronged: Trainers work with children directly 20 times over 5 months, and parents give the massage daily to their children. Improvement was evaluated in two settings--preschool and home--by teachers (blind to group) and parents. Teacher evaluations showed that treated children had significant classroom improvement of social and language skills and reduction in autistic behavior compared with wait-list control participants. These findings were confirmed by parent data, indicating that the gains had generalized across contexts. A model and supporting data for understanding and treating sensory and self-regulation problems in autism is presented.

In this study, glass rods suspended at the air-water interface in the runoff channel of Fairy Geyser, Yellowstone National Park, WY, were used as a substratum to promote the development of biofilms that resembled multilayered mat communities in the splash zone at the geyser's source. This approach enabled the establishment of the temporal relationship between the appearance of Cyanobacteria, which ultimately formed the outer green layer, and the development of a red underlayer containing Roseiflexus-like Chloroflexi. This is the first study to define time-dependent successional events involved in the development of differently colored layers within microbial mats associated with many thermal features in Yellowstone National Park. Initial (1-month) biofilms were localized below the air-water interface (60 to 70 degrees C), and the majority of retrieved bacterial sequence types were similar to Synechococcus and Thermus isolates. Biofilms then shifted, becoming established at and above the air-water interface after 3 months. During winter sampling (6 to 8 months), distinct reddish orange microcolonies were observed, consistent with the appearance of Roseiflexus-like sequences and bacteriochlorophyll a pigment signatures. Additionally, populations of Cyanobacteria diversified to include both unicellular and filamentous cell and sequence types. Distinct green and red layers were observed at 13 months. Planctomycetes-like sequences were also retrieved in high abundance from final biofilm layers and winter samples. Finally, biomass associated with geyser vent water contained Roseiflexus-like sequence types, in addition to other high-abundance sequence types retrieved from biofilm samples, supporting the idea that geothermal water serves as an inoculum for these habitats.

Unlabelled: Attitudes and beliefs of health care providers, in conjunction with a nonthreatening physical environment, are important components in establishing a constructive and supportive climate for care of overweight and obese students., Objective: The authors explored providers' attitudes about obesity and assessed the physical environment in a student health clinic to identify areas that may be detrimental to the care of overweight and obese students., Participants: Eighteen direct care providers participated in the project., Methods: The authors conducted focus groups with direct care providers and assessed their experiences and perceived challenges in working with overweight and obese students. The authors also conducted a walk-through assessment of the physical environment., Results: Direct care providers expressed discomfort in deciding how and when to discuss weight with students. The authors found that elements of the physical environment could present barriers to care for overweight and obese students., Conclusions: The authors make recommendations for improving the health care climate for overweight and obese students.

Sensory impairment is a common and significant feature of children on the autism spectrum. In 2005, a qigong massage intervention based on Chinese medicine and delivered by a doctor of Chinese medicine was shown to improve sensory impairment and adaptive behavior in a small controlled study of young children with autism. In 2006, the Qigong Sensory Training (QST) program was developed to train early intervention professionals to provide the QST intervention. This article describes the preliminary evaluation of the QST program as piloted with 15 professionals and 26 children and outcomes testing using standardized tests of sensory impairment and adaptive behavior. Results of outcomes comparing delivery by QST-trained therapists with delivery by a doctor of Chinese medicine showed that both groups improved and that there was no difference in outcome between the two groups. The intervention and training program are described, and implications for future research are discussed.

The traffic in concubines flourished in Ming-Qing Jiangnan as a result of large scale interactions of political and socioeconomic contexts. How women were situated within the system is central to this study, which revolves around two major arguments. First, the traffic in concubines as a means for disaster relief during difficult times was legitimized as a benevolent policy. Second, women were not necessarily the victims of the commercialized market in concubines. To study concubinage in general and individual concubines in the market system in Jiangnan, the following issues command attention: the political and socioeconomic conditions fostering concubinage, the market system of women, the roles of brokers, the value indicators and resultant prices, the transaction procedures for the sale of women with specific contents of contracts, the effects of the market system on the concubines' lives, and the regulations of law and the judicial practice in penal cases.

Objective: There is a lack of empirical evidence of effectiveness for instructional interventions for children with traumatic brain injury (TBI). This article addresses this issue by providing an in-depth examination of instructional methodologies validated with other populations of students (with and without disability) and their potential for teaching children with TBI., Design: Literature review., Conclusions: Two instructional approaches--Direct Instruction and cognitive strategy intervention--have significant evidence supporting their use with many populations of children, with and without disabilities, and address many of the common needs and learning characteristics of students with TBI, thus showing particular promise for these students. Given the efficacy of these 2 approaches with students with similar learning and behavioral characteristics, the authors recommend establishing and funding a systematic research agenda to test their effectiveness with students with TBI.

This article examines the instructional research literature pertinent to teaching procedures or information to individuals with acquired memory impairments due to brain injury or related conditions. The purpose is to evaluate the available evidence in order to generate practice guidelines for clinicians working in the field of cognitive rehabilitation. A systematic review of the instructional literature from 1986 to 2006 revealed 51 studies meeting search criteria. Studies were analysed and coded within the following four key domains: Population Sample, Intervention, Study Design, and Treatment Outcomes. Coding included 17 characteristics of the population sample; seven intervention parameters; five study design features; and five treatment outcome parameters. Interventions that were evaluated included systematic instructional techniques such as method of vanishing cues and errorless learning. The majority of the studies reported positive outcomes in favour of systematic instruction. However, issues related to the design and execution of effective instruction lack clarity and require further study. The interaction between the target learning objective and the individual learner profile is not well understood. The evidence review concludes with clinical recommendations based on the instructional literature and a call to clinicians to incorporate these methods into their practice to maximise patient outcomes.

The Portulacaceae is one of the few terrestrial plant families known to have both C(4) and Crassulacean acid metabolism (CAM) species. There may be multiple origins of the evolution of CAM within the Portulacaceae but the only clear evidence of C(4) photosynthesis is found in members of the genus Portulaca. In the Portulaca, CAM succulent tissue is overlaid with the C(4) tissue in a unique fashion where both pathways are operating simultaneously. Earlier reports have shown that the clade containing the genera Anacampseros and Grahamia may also contain C(4) photosynthetic species similar to the Portulaca, which would indicate multiple origins of C(4) photosynthesis within the family. The aim of the present study was to ascertain the true photosynthetic nature of these genera. An initial survey of the carbon isotope composition of the Anacampseros ranged from -12.6 per thousand to -24.0 per thousand, indicating very little CAM activity in some species, with other values close to the C(4) range. Anacampseros (=Grahamia) australiana which had been previously identified as a C(4) species had a carbon isotope composition value of -24.0 per thousand, which is more indicative of a C(3) species with a slight contribution of CAM activity. Other Anacampseros species with C(4)-like values have been shown to be CAM plants. The initial isotope analysis of the Grahamia species gave values in the range of -27.1 per thousand to -23.6 per thousand, placing the Grahamia species well towards the C(3) photosynthetic range. Further physiological studies indicated increased night-time CO(2) uptake with imposition of water stress, associated with a large diurnal acid fluctuation and a marked increased phosphoenolpyruvate carboxylase activity. This showed that the Grahamia species are actually facultative CAM plants despite their C(3)-like carbon isotope values. The results indicate that the Grahamia and Anacampseros species do not utilize the C(4) photosynthetic pathway. This is the first to identify that the Grahamia species are facultative CAM plants where CAM can be induced by water stress. This work supports earlier physiological work that indicates that this clade containing Anacampseros and Grahamia species comprises predominantly facultative CAM plants. This report suggests there may be only one clade which contains C(4) photosynthetic members with CAM-like characteristics.

Effects of maternal eating behaviors and attitudes, maternal feedback to daughter about weight issues, mother-daughter relationship closeness, media influences, and mothers' perceptions of daughters shape on daughters' body image and eating pathology were examined using 91 pairs of mothers and college-aged daughters. Hierarchical multiple regressions using daughters' BMI as the first step were separately performed for daughters' body image and eating pathology. Variables predictive of daughters' body image included negative feedback from mother, mother's disapproval of daughter's figure, and mothers' eating behaviors and attitudes as perceived by daughters. A similar pattern was found for daughters' eating pathology scores with the addition of mothers' tendency to internalize media messages regarding thinness and beauty significantly adding to the prediction. Maternal influence through modeling may be best assessed by using the daughters' perceptions of their mothers because this corresponds to what the daughter was aware of in their mothers' eating attitudes and behaviors. Negative feedback from mothers about daughters' figures and eating patterns significantly increased daughters' difficulties in these areas. Mothers who showed a greater internalization of media messages about thinness were most likely to have daughters with eating pathologies.

Background: Four elementary (primary) school students with severe speech and physical impairments (SSPI) who used augmentative and alternative communication (AAC) aids were selected to take part in an intensive, 4-week summer intervention program. The program was designed to explore effective approaches, content and contexts for supporting communication (including oral language, literacy, and technology skills) among young people who require AAC., Method: Features of the intervention included (i) using an integrated approach to provide language and literacy opportunities intended to elicit the students' active involvement in meaningful, productive and expressive tasks in everyday contexts; (ii) constant modelling of AAC usage; (iii) requiring family involvement as a criterion for participation in the program; and (iv) follow-up visits to schools during which effective instructional strategies were shared with staff., Results: Formative and summative assessment measures revealed that all four participants made progress during intervention. However two of the students maintained these gains into the follow-up period, whereas the other two did not. Each pair seemed to share certain characteristics, which are illustrated in this paper by two case study synopses. One relates the story of a child whose successes continued into the follow-up period, and the other chronicles the experiences of the child whose successes quickly waned., Conclusions: This study provides a range of instructional approaches, curricula and contexts to promote communication for children with complex communication needs. These instructional supports are more likely to improve access to inclusion in schools that seek to work in partnership with parents, plan educational transitions, and implement adequate training and awareness-raising among their staff.

Nearly all older adults experience social losses, which can disrupt their social support networks and impair their quality of life. Events such as retirement, an inability to drive, death of a spouse and/or close life-long friends, or moving to an elder care facility may negatively affect the quality of older adults' social support networks. Low levels of perceived social support are associated with increased depression, impaired immune functioning and reduced life expectancy. Moreover, social interactions can be cognitively stimulating and may help older adults preserve their cognitive abilities. In the present study, institutionalized older adults were exposed to either a cognitive enhancement programme designed to enhance social networks or a control group. Measures of perceived social support and loneliness were administered before and after a 3-month, group-based intervention. There was a significant interaction between group and time. Those who did not participate in the intervention experienced a decrease in perceived social support and an increase in perceived loneliness. Participants in the intervention group stayed the same on the above measures. Helping older adults increase or maintain the quality of their social networks may lead to enhanced cognitive functioning, decreased depression and improved quality of life. Recommendations to help assisted living facilities, nursing homes, retirement communities and senior centres develop social and cognitive interventions are provided.

As the empirical literature on maladaptive eating patterns has grown, the importance of longitudinal studies in establishing causal risk factors has become apparent. The current study reports longitudinal data gathered from the first 20 months of college for female students (n=117). Eating pathology was assessed using a composite measure from the Eating Disorders Inventory. Variables examined as potential risk factors included depression, reassurance seeking, perfectionism, impulsiveness, body dissatisfaction, and stressful events. Eating symptoms were quite stable across the 20-month interval (r=0.68). Although all of the potential risk variables showed significant correlations with eating symptoms, hierarchical regressions controlling for eating symptoms at Time 1 indicated that perfectionism, impulsiveness, and body dissatisfaction failed to uniquely add to the prediction of eating symptoms at Time 2. Depression, reassurance seeking and stressful events did add to this prediction. Failure to find support for variables in a longitudinal design may be due to the age of participants and relative stability of eating symptoms. Perfectionism, and body dissatisfaction may play a causal role in developing eating symptoms at earlier ages, but do not continue to influence the course of these symptoms in late adolescence. Negative affect (depression), needing reassurance in social relationships, and having to deal with stressful events seem to be risk factors for increased eating symptoms in late adolescence.

In clinical research, sensory impairment is considered one of the core deficits in autism and is associated with impaired socialization, behavioral disturbances and bowel and sleep problems. The effectiveness of the Cignolini methodology, an original Qigong massage methodology, in treating sensory impairment in young children with autism was evaluated in a small, controlled study. Thirteen children with autism between the ages of three and six received daily treatment according to the methodology for 5 months. Compared with untreated children, treated children experienced significant improvement of their sensory impairment (p < 0.01), and demonstrated increased social skills (p < 0.04) and basic living skills (p < 0.02) on standardized measures. In addition, all of the children with bowel and sleep abnormalities demonstrated improvement after treatment.

Infants who start receiving immunizations on time are more likely to be up to date at age 2 years. Among 39708 infants aged 3 months covered by the Oregon Health Plan (expanded Medicaid), those who did not have health care coverage within the first month of life were less likely to start receiving immunizations on time. Also at risk were infants in foster care, in subadoptive care, who were blind or disabled, who were Native American or Black, or whose mothers were not covered by the Oregon Health Plan.

The deaf education profession faces a critical juncture. First, the 2006 leadership crisis that swept deaf education's flagship institution--Gallaudet University--will propel professionals to think deeply about promoting diversity, equity, and access in deaf education teacher and leadership preparation programs. Second, personnel shortages require attention: Teacher and leadership voids in university and K-12 programs loom if training efforts are not increased. Teaching and leadership needs center on three challenges: (a) understanding the changing demographic composition of the student, teacher, and leadership populations; (b) developing an evolving curriculum founded on research-based practices; (c) continuing to enlarge the knowledge base through applied research in the social sciences. Two case studies examine teacher training and leadership programs at universities that address these challenges. The importance of workplace deaf-hearing bicultural teams is examined. Implications for the preparation of teacher and leadership personnel in deaf education are discussed.

Primary Objective: The purpose of this pilot study was to evaluate an instructional package that facilitates learning and retention of multi-step procedures for persons with severe memory and executive function impairments resulting from traumatic brain injury., Research Design: The study used a multiple baseline across participants design., Methods and Procedures: Four participants, two males and two females, ranging in age from 36-58 years, were taught a 7-step e-mail task. The instructional package (TEACH-M) was the experimental intervention and the number of correct e-mail steps learned was the dependent variable., Main Outcomes and Results: Treatment effects were replicated across the four participants and maintained at 30 days post-treatment. Generalization and social validity data further supported the treatment programme., Conclusions: The results suggest that individuals with severe cognitive impairments are capable of learning new skills. Directions for future research include application of the instructional package to other multi-step procedures.

The primary objective of this study was to better understand the technology needs, barriers and strategies of individuals with acquired cognitive impairments (ACI) in order to design and modify technologies with potential for alleviating the diminished independence and social isolation common in this population. The authors hypothesized that (1) higher rates of computer use would be reported by younger, more highly educated individuals with ACI, those with less severe injuries and those with previous computer experience; (2) A low percentage of survey respondents would own their own computers; and (3) People with ACI would experience social isolation and report low frequency of connecting with important people who live far away. A total of 133 individuals with ACI, professionals and care providers completed the survey. To gain more specific information, seven focus groups were conducted with 66 individuals with ACI and 20 care providers. Finally, 10 current email users participated in structured conversations, detailing their strategies for using email. The survey revealed that 80% of subjects with ACI reported owning a computer. Age and education were not predictors of computer use, but individuals whose ACI was the result of more severe injuries were less likely to use computers. As expected, respondents reported that maintaining contact with distant loved ones is problematic. The focus groups and conversations provided more detail about the communication needs of the population and the relative advantages and disadvantages of email compared with telephone and mail. Participants also identified barriers to email use they had encountered or feared they would encounter when using email. A number of accommodations to overcome these barriers were suggested. The results of the survey, focus groups and conversations confirmed the utility of email and other technologies for people with ACI and the need to make these technologies more accessible. The results and suggestions provided by the focus groups and interviews are being used in the design of Think and Link, an email interface for use by individuals with ACI.

The effects of self evaluation on the P300 event-related potential (ERP) were explored with 56 participants (16 men, 40 women; M age = 23.4 yr., SD = 1.2) across three conditions. The conditions included (1) a standard ERP auditory oddball discrimination between a random target (15% occurrence) and standard stimuli (85% occurrence), (2) the oddball task followed by the additional cognitive task of maintaining a mental count of the target tones, and (3) the oddball task followed by the additional cognitive task of self-evaluating whether they felt surprised by the current occurrence of the target tone. The added cognitive requirements for Conditions 2 and 3 required the subjects to maintain a cognitive readiness for the secondary stimulus-related task during their sensory discrimination response for the standard oddball task. During the self-evaluation condition, the P300 amplitude was significantly larger across all recording locations than the regular oddball condition and the cognitive count condition.

Latina mothers in the United States enjoy surprisingly favorable birth outcomes despite their social disadvantages. This "Latina paradox" is particularly evident among Mexican-born women. The social and cultural factors that contribute to this paradox are maintained by community networks--informal systems of prenatal care that are composed of family, friends, community members, and lay health workers. This informal system confers protective factors that provide a behavioral context for healthy births. US-born Latinas are losing this protection, although it could be maintained with the support of community-based informal care systems. We recommend steps to harness the benefits of informal systems of prenatal care in Latino communities to meet the increasing needs of pregnant Latina women.

The purpose of this study was to assess the effects of water, lavender, or rosemary scent on physiology and mood state following an anxiety-provoking task. The nonsmoking participants, ages 18-30 years, included 42 women and 31 men who reported demographic information and measures of external temperature and heart rate were taken prior to introduction of an anxiety-eliciting task and exposure to lavender, rosemary, or water scents. Following the task, participants completed the Profile of Mood States to assess mood, and temperature and heart rate were reassessed. Participants rated the pleasantness of the scent received. When pleasantness ratings of scent were covaried, physiological changes in temperature and heart rate did not differ based on scent exposure, but mood ratings differed by scent condition. Participants in the rosemary condition scored higher on measures of tension-anxiety and confusion-bewilderment relative to the lavender and control conditions. The lavender and control conditions showed higher mean vigor-activity ratings relative to the rosemary group, while both rosemary and lavender scents were associated with lower mean ratings on the fatigue-inertia subscale, relative to the control group. These results suggest that, when individual perception of scent pleasantness is controlled, scent has the potential to moderate different aspects of mood following an anxiety-provoking task.

Context: A growing number of women are being diagnosed and successfully treated for breast cancer. Therefore, many women are living with a history of breast cancer. The use of complementary and alternative therapies within this patient population has increased., Objective: To determine post breast cancer treatment health behaviors with regard to use of complementary and alternative therapies., Design: Survey participants were asked about their use of 15 complementary and alternative medicine (CAM) therapies. In order to determine the relative importance of the hypothesized predictor variables, standard logistic regression was performed with CAM use as the dependent variable., Participants: 551 women who had been diagnosed with breast cancer and were post treatment., Intervention: Telephone Survey., Results: Telephone interviews were conducted with 551 females in the Portland, Oregon, metropolitan area who had been diagnosed with breast cancer an average of 3.5 years earlier. Two-thirds (66%) of the women used at least one CAM therapy during the previous 12 months, and the majority of them perceived that their CAM use was without the recommendation of their doctor. Relaxation/meditation, herbs, spiritual healing, and megavitamins were used most often. Significant predictors of CAM use included younger age, higher education, and private insurance. The majority of the CAM therapies were perceived by their users to be at least "moderately important" in remaining free of cancer. The reasons given for using CAM were to enhance overall quality of life, to feel more in control, to strengthen the immune system, and to reduce stress., Conclusions: Two-thirds of women in this study followed conventional treatment for breast cancer with one or more CAM therapies, which, they believed, could prevent cancer recurrence and/or improve their quality of life. CAM use did not reflect negative attitudes towards conventional medical care, but rather an orientation to self-care in the optimization of their health and well being.

Since 1991, when Traumatic Brain Injury (TBI) was established as a disability category under IDEA, educators nationwide have become increasingly aware of the unique and complex challenges these students present. Yet professionals, advocates and family members share a growing concern that the instructional needs of these students are not being met. School personnel serving these students need systematic support that includes both information about specific aspects of the student's disability and access to expert technical assistance. The goal of the TBI Team model, as developed and implemented in Iowa, Kansas, and Oregon, is to make available to schools statewide a group of well-trained peer consultants who can provide in-service training and ongoing consultation. The TBI Team model has four components: (a) needs assessment, (b) team recruitment, (c) team training, and (d) evaluation of both implementation and outcomes. Trained Team members provide in-service training, classroom consultation, and information and resources for school staff and parents. Team operations are maintained and supported through a central office at the Department of Education. Evaluation data suggest that the Team model is a cost effective and efficient approach to supporting teachers who work with students with TBI.

This paper originates from a presentation at the IIIrd International Congress on Crassulacean Acid Metabolism, Cape Tribulation, Queensland, Australia, August 2001. Portulaca grandiflora (Lind.) is a succulent species with C4 photosynthesis and crassulacean acid metabolism (CAM) cycling in leaves, and CAM-idling type photosynthesis in stems. We investigated the level and localization of carbon fixation enzymes and photosynthetic activity of leaves and stems of P. grandiflora under well-watered and drought conditions. As CAM activity increased during water stress, the leaf water-storage tissue collapsed, presumably transferring water to the bundle sheath and mesophyll cells, and so maintaining the C4 photosynthetic pathway. Tissue prints indicated an increase in phosphoenolpyruvate carboxylase (PEPC) in the water-storage tissue of leaves and the cortex of stems. Immunoblot analyses after 10 d of water stress showed that leaves had a slight decrease in the proteins of the C4-CAM pathway, while at the same time a new isoform of NADP-malic enzyme (NADP-ME) appeared. In contrast, the stem showed increases in proteins of the CAM pathway when water stressed. Under water stress, diurnal fluctuation in acidity in leaves was not accompanied by a net gain or loss of CO2 at night, and there was sustained, but decreased, fixation of CO2 during the day, characteristic of CAM cycling. High gross rates of O2 evolution were maintained during the day under water stress, suggesting induction of alternative electron sinks. With induced diurnal fluctuations in acidity in stems, there was no net carbon gain during the day or night. These results demonstrate, for the first time, that the stem of P. grandiflora is an inducible CAM-idling tissue. Our results also indicate that the C4 and CAM pathways operate independently of one another in P. grandiflora.

We have developed a ten-week curriculum for molecular biology that uses 16S ribosomal RNA genes to characterize and compare novel bacteria from hot spring communities in Yellowstone National Park. The 16S rRNA approach bypasses selective culture-based methods. Our molecular biology course offered the opportunity for students to learn broadly applicable methods while contributing to a long-term research project. Specifically, students isolated and characterized clones that contained novel 16S rRNA inserts using restriction enzyme, DNA sequencing, and computer-based phylogenetic methods. In both classes, students retrieved novel bacterial 16S rRNA genes, several of which were most similar to Green Nonsulfur bacterial isolates. During class, we evaluated student performance and mastery of skills and concepts using quizzes, formal lab notebooks, and a broad project assignment. For this report, we also assessed student performance alongside data quality and discussed the significance, our goal being to improve both research and teaching methods.

We characterized and compared five geographically isolated hot springs with distinct red-layer communities in Yellowstone National Park. Individual red-layer communities were observed to thrive in temperatures ranging from 35 to 60 degrees C and at pH 7 to 9. All communities were dominated by red filamentous bacteria and contained bacteriochlorophyll a (Bchl a), suggesting that they represented novel green nonsulfur (GNS) bacteria. The in vivo absorption spectra of individual sites were different, with two sites showing unusual Bchl a protein absorption bands beyond 900 nm. We prepared and analyzed 16S rRNA libraries from all of these sites by using a combination of general bacterial primers and new GNS-specific primers described here. These studies confirmed the presence of novel GNS-like bacteria in all five communities. All GNS-like clones were most similar to Roseiflexus castenholzii, a red filamentous bacterium from Japan that also contains only Bchl a. Phylogenies constructed by using GNS-like clones from Yellowstone red-layer communities suggest the presence of a moderately diverse new "red" cluster within the GNS lineage. Within this cluster, at least two well-supported subclusters emerged: YRL-A was most similar to Roseiflexus and YRL-B appeared to be novel, containing no known isolates. While these patterns showed some site specificity, they did not correlate with observed Bchl a spectrum differences or obvious features of the habitat.

Objective: Women entering college (N = 118) were longitudinally followed for 3 years with assessments of eating pathology (Restraint and Bulimia)., Method: Measures taken at Time 1 included timing of onset of puberty, Figure Dissatisfaction, Ineffectiveness, Public Self-Consciousness, and mood states (Profile of Mood States). Measures were evaluated as predictors of changes in Restraint and Bulimia scores across the three-year period., Results: Both Restraint (r = .69) and Bulimia (r = .50) were quite stable across the 3 years. Mean weight gain of 5.4 pounds (p < .001) was paralleled by an increase in "ideal weight" of 4.7 pounds. Hierarchical regressions controlling for Time 1 levels of eating disorder symptoms revealed that changes in Bulimia (R(2) = .38, p < .0001) were related to the psychological measures and to Figure Dissatisfaction. Changes in Restraint (R(2) = .61, p < .0001) were significantly related to Figure Dissatisfaction., Discussion: Findings are discussed in the context of the value of longitudinal designs in identifying risk factors. Dissatisfaction with one's figure seems to be consistently related to worsening eating pathology., (Copyright 2001 by John Wiley & Sons, Inc.)

The authors assessed eating behaviors and attitudes of 225 college freshman women on the bulimia and restraint scales at the beginning of the year. Seven months later, they reassessed 104 of the original students. Concurrent data regression analyses found that symptoms of eating pathology were associated with figure dissatisfaction, ineffectiveness, public self-consciousness, and vigor on the Profile of Mood States, and for bulimia, self-efficacy to control eating when experiencing negative feelings, and reward conditions. Both bulimia and restraint were highly stable across the 7 months. Prospective analyses, controlling for the initial level of eating pathology in hierarchical regressions, found that figure dissatisfaction, ineffectiveness, and alcohol use/abuse over the past year were significant predictors of worsening symptoms. Beginning levels of bulimia and restraint were the best predictors of eating pathology at the end of the study. The roles that self-image and alcohol use may play as vulnerabilities for eating pathology are also considered.

This study was designed to assess the differential value of several psychological variables with regard to predicting safe-sex behavior. A sample of 94 male and 179 female undergraduate students, ranging in age from 16 to 66 years, were surveyed about sexual issues related to safe-sex practices. The survey included scales measuring participants' knowledge of transmission of AIDS, self-perception of safe-sex communication, fear and concern about AIDS, attitudes toward AIDS victims, and self-report of risky behavior. Several interesting relationships among predictor variables were found. For instance, favorable attitudes toward AIDS victims were positively correlated with knowledge about AIDS transmission, perceived communication with partners about safe sex, and fear of acquiring AIDS. However, only two predictor variables were independently predictive of self-reports of risky sexual behavior; specifically, fear about AIDS transmission was positively correlated with risky behavior, while communication was negatively correlated with risky behavior. These data suggest a need for a model that allows for complex, reciprocal relationships between the cognitive, emotional, and behavioral components of safe-sex practice. Implications are applied to research with college populations.

The induction of Crassulacean acid metabolism in M:esembryanthemum crystallinum was investigated in response to foliar application of gibberellic acid (GA). After 5 weeks of treatment, GA-treated plants showed 1.7- to almost a 4-fold increase of phosphoenolpyruvate carboxylase (PEPcase) activity with a concomitant increase in acid metabolism when compared to control plants. Immunoblot analysis indicated an increase in the PEPcase protein similar to that of salt treatment while Rubisco did not show a similar rise. The results indicate that exogenously applied GA accelerates plant developmental expression of PEPcase and Crassulacean acid metabolism in M: crystallinum.

Reformulation of adolescent egocentrism suggests that personal fable and imaginary audience ideations extend into adulthood. To test this proposition, adolescents (aged 14-18) and adults (aged 20-89) completed subscales of the adolescent egocentrism, self-consciousness and interpersonal reactivity scales. An across scale comparison first ensured that adolescent egocentrism measures were comparable across age. Next, MANOVAs revealed higher egocentrism scores for adolescents vs. adults (p<0.05), but no difference between adolescents and younger (19-30) adults after splitting adults into younger (19-30), middle (31-59) and older (60+) subgroups. Results suggest that personal fable and imaginary audience are not confined to adolescence.

Using logistic regression to calculate odds ratios and confidence intervals, this secondary analysis determined statistically significant predictors and prevalence rates for high school students in the United States who carried a weapon, were threatened or injured with a weapon, or were involved in physical fighting on school property from 1993-1995. Geographic region, grade in school, race/ethnicity, and gender were the independent variables. Data regarding school-related violence among adolescents were collected in 1993 and 1995 using the Youth Risk Behavior Survey developed and implemented by the Centers for Disease Control and Prevention. Results indicated gender, race, and grade in school were predictors of school-related violence for students in grades 9-12 from 1993 to 1995. Males were involved in violent acts more often than females. Minority students, especially Hispanics and Blacks, and students in lower grades at school participate in and are victims of violence more often than other students.

Despite previous work showing that mothers, fathers, and siblings provide negative evidence regarding children's grammatical errors, the role of linguistic input remains controversial. Since most work in this area has concentrated on negative evidence in the mother-child dyad, this study extended prior work by comparing mothers', fathers' and siblings' corrective repetitions to children's errors across different family settings. Fourteen children (2;3) were videotaped interacting with their mothers, fathers, and siblings (4;1) in dyad, triad, and tetrad settings. Analyses revealed that mothers and fathers provided more corrective repetitions than siblings did. Although the size of the setting did not differentiate responding, when specific configurations were examined differences emerged. Analyses of individual families revealed that all children received feedback following syntax errors. These results are discussed in terms of current negative evidence research.

This study examined the response to acidic conditions of four gonococcal isolates -NRL38874 (Proto/IB-2), NRL38884 (Pro/IA-2), NRL38953 (Proto/IB-3) and NRL39029 (Pro/IA-3) - obtained from various sites in patients in whom a diagnosis of pelvic inflammatory disease had been made by laparoscopic examination. Acid tolerance of the clinical isolates was strain and growth phase dependent. Growth of the four strains on solid media was undetectable below pH 5.8. In liquid culture, strain NRL38884 did not survive below pH 5.2; strains NRL38874, NRL38953 and NRL39029 survived to pH 4.5. Between pH 4.2 and pH 5.1, the latter three strains exhibited a peak in survival at pH 4.6-4.7 during log phase, suggesting that there may be a distinct acid tolerance system operating at this pH. SDS-PAGE of whole-cell, total membrane and outer-membrane fractions of the four strains prepared from pH 7.2 and pH 6.1 plate cultures revealed numerous differences in protein composition. Acidic conditions reduced the expression of the reduction modifiable outer-membrane protein Rmp, and induced the expression of many membrane proteins, including gonococcal hsp63. Immunoblotting studies with matched serum samples and strains from patients with pelvic inflammatory disease indicated that IgG recognition of outer-membrane components from strains cultured in acidic and neutral conditions was quite different. The results suggest that the immune system interacts with unique outer-membrane constituents on gonococci colonising sites at different pH.

College students who reported recent weight fluctuations of 15 pounds represented 15% of the men (N = 161) and 22% of the women (N = 301) in the study. Comparisons were made with students whose weight had remained stable on 4 subscales of the Eating Disorders Inventory (Bulimia, Body Dissatisfaction, Drive for Thinness, and Interoceptive Awareness), on the Washington Self-Description Questionnaire, and on the Situational Appetite Measure. A MANOVA supported gender differences, with women showing greater levels of body dissatisfaction and concern for thinness. Students whose weight had fluctuated were differentiated from students whose weight had been stable, with weight fluctuations being most strongly related to greater body dissatisfaction and lower levels of self-efficacy for control of eating. Results support the use of a relapse model for weight fluctuation, emphasizing the potential importance of low self-efficacy as a moderator of repeated weight fluctuation.