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1,324 results on '"Warner T"'

151. Plasma microRNA levels in patients with acute coronary syndrome are associated with platelet function

Author

Bender, L., primary, Mayr, M., additional, Kaudewitz, D., additional, Skroblin, P., additional, Willeit, P., additional, Morton, A., additional, Gracio, F., additional, Dudek, K., additional, Langley, S., additional, Kiechl, S., additional, Warner, T., additional, De Rinaldis, E., additional, Zampetaki, A., additional, Saxena, A., additional, and Storey, R., additional

Published
2014
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155. Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors

Author

MITCHELL J. A., KOHLHAAS K. L., WARNER T. D., MURAD F. AND VANE J. R., SORRENTINO, RAFFAELLA, Mitchell, J. A., Kohlhaas, K. L., Sorrentino, Raffaella, Warner, T. D., and Murad, F. AND VANE J. R.

Abstract

Male Sprague-Dawley or Wistar rats were injected with bacterial lipopolysaccharide (LPS; 5 mg kg-1, i.p.) and killed after 1, 3, 6, 15, and 24 h. The brains, mesenteries, spleens, lungs, livers, kidneys, hearts, aortae and diaphragms were removed and frozen immediately. Control rats were injected with sterile saline and killed after 6 h. 2. The organs were homogenized in a semi-frozen state and NO synthase (NOS) activity measured in tissues from both LPS-treated and saline-treated groups by the ability of homogenates to convert [3H]-L-arginine to [3H]-L-citrulline in a NADPH-dependent manner. 3. The NOS activity in all organs taken from control animals was found to be calcium-dependent, with the highest activity being in the brain. After LPS-treatment an induced calcium-independent NOS was detected in all tissues tested, with the exception of the brain. The spleen, lung, mesentery and liver had the highest amounts of LPS-induced NOS activity. No induction of calcium-dependent NOS was detected. 4. Induction of NOS was maximum 6 h after administration of LPS and had returned to control levels in 24 h. 5. The constitutive NOS in brain and mesentery and the LPS-induced activities in the spleen, lung, liver and mesentery were inhibited by NG-monomethyl-L-arginine (L-NMMA) or NG-nitro-L-arginine methyl ester (L-NAME) according to concentration. The IC50 for L-NAME was 2.5 microM against the constitutive NOS from brain, and 20-25 microM against the inducible NOS. For L-NMMA the IC50 was 20-25 microM against either NOS isoform. 7. The vascular responses to endothelin-I (ET-1), the thromboxane A2-mimetic 11 alpha,9 alpha-epoxymethanoprostaglandin F2alpha (U46619), phenylephrine (PE) or 5-hydroxytryptamine (5-HT) were measured in the simultaneously perfused arterial and venous mesenteric vascular beds from both control and LPS-treated(6 h) rats. Vasoconstrictor responses to all agonists tested were unaffected by LPS treatment. In the presence of L-NAME (100 microM) vasoconstrictor responses were potentiated in both the arterial and venous portion of the mesenteric beds from both control and LPS-treated rats. The potentiation of responses to U46619 was significantly greater in beds from LPS-treated rats.8. Injection of LPS i.p. is associated with induction of NOS in all organs tested, except for the brain. In the mesentery this is not accompanied by a hyporesponsiveness to constrictor agents suggesting an increased sensitivity, particularly to U46619. This may explain the poor perfusion and tissue damage in the splanchnic circulation associated with sepsis

Published
1993

164. The dystonias

Author

Jarman, P R and Warner, T T

Subjects
Research Article
Published
1998

165. ARE PSYCHIATRIC SYMPTOMS A CORE PHENOTYPE OF MYOCLONUS DYSTONIA SYNDROME CAUSED BY SGCE MUTATIONS?

Author

Peall, K., primary, Smith, D., additional, Kurian, M., additional, Wardle, M., additional, Waite, A., additional, Hedderly, T., additional, Lin, J., additional, Smith, M., additional, Whone, A., additional, Pall, H., additional, White, C., additional, Lux, A., additional, Jardine, P., additional, Bajaj, N., additional, Lynch, B., additional, Kirov, G., additional, O'Riordan, S., additional, Samuel, M., additional, Lynch, T., additional, King, M., additional, Chinnery, P., additional, Warner, T., additional, Blake, D., additional, Owen, M., additional, and Morris, H., additional

Published
2013
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168. 265 PLASMA MICRORNAS AS BIOMARKERS FOR PLATELET INHIBITION

Author

Willeit, P, primary, Zampetaki, A, additional, Kaudewitz, D, additional, Lee, R, additional, Dudek, K, additional, King, A, additional, Kirkby, N S, additional, Markus, H S, additional, Warner, T D, additional, Kiechl, S, additional, Morton, A C, additional, Channon, K, additional, Storey, R F, additional, and Mayr, M, additional

Published
2013
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170. Luminosity of initial breakdown in lightning

Author

Stolzenburg, M., primary, Marshall, T. C., additional, Karunarathne, S., additional, Karunarathna, N., additional, Vickers, L. E., additional, Warner, T. A., additional, Orville, R. E., additional, and Betz, H.‐D., additional

Published
2013
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173. Digital forestry: a white paper

Author

Zhao, G., Shao, G., Reynolds, K.M., Wimberly, M.C., Warner, T., Moser, J.W., Rennolls, K., Magnussen, S., Köhl, M., Anderson, H.-E., Mendoza, G.A., Dai, L., Huth, Andreas, Zhang, L., Brey, J., Sung, Y., Ye, R., Martin, B.A., Li, F., Zhao, G., Shao, G., Reynolds, K.M., Wimberly, M.C., Warner, T., Moser, J.W., Rennolls, K., Magnussen, S., Köhl, M., Anderson, H.-E., Mendoza, G.A., Dai, L., Huth, Andreas, Zhang, L., Brey, J., Sung, Y., Ye, R., Martin, B.A., and Li, F.

Abstract

Digital Forestry has been proposed as "the science, technology, and art of systematically acquiring, integrating, analyzing, and applying digital information to support sustainable forests." Although rooted in traditional forestry disciplines, Digital Forestry draws from a host of other fields that, in the past few decades, have become important for implementing the concept of forest ecosystem management and the principle of sustainable forestry. Digital Forestry is a framework that links all facets of forestry information at local, national, and global levels through an organized digital network. It is anticipated that a new set of principles will be established when practicing Digital Forestry concept for the evolution of forestry education, research, and practices as the 21st century unfolds.

Published
2005

174. PRRT2 gene mutations: From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine

Author

Gardiner, A. R., primary, Bhatia, K. P., additional, Stamelou, M., additional, Dale, R. C., additional, Kurian, M. A., additional, Schneider, S. A., additional, Wali, G. M., additional, Counihan, T., additional, Schapira, A. H., additional, Spacey, S. D., additional, Valente, E.-M., additional, Silveira-Moriyama, L., additional, Teive, H. A. G., additional, Raskin, S., additional, Sander, J. W., additional, Lees, A., additional, Warner, T., additional, Kullmann, D. M., additional, Wood, N. W., additional, Hanna, M., additional, and Houlden, H., additional

Published
2012
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175. 1624 Myoclonus dystonia: a clinical and genetic description: Table 1

Author

Peall, K, primary, Waite, A J, additional, Kurian, M A, additional, Hedderly, T, additional, Smith, M, additional, Lin, J P, additional, Warner, T T, additional, Pall, H, additional, Chinnery, P, additional, Whone, A, additional, Owen, M J, additional, Blake, D J, additional, and Morris, H R, additional

Published
2012
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182. Effect of clopidogrel withdrawal on platelet reactivity and vascular inflammatory biomarkers 1 year after drug-eluting stent implantation: results of the prospective, single-centre CESSATION study

Author

Sambu, N., primary, Dent, H., additional, Englyst, N., additional, Warner, T. D., additional, Leadbeater, P., additional, Roderick, P., additional, Gray, H., additional, Simpson, I., additional, Corbett, S., additional, Calver, A., additional, Morgan, J., additional, and Curzen, N., additional

Published
2011
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197. Numerical simulations of a transverse indirect circulation and low-level jet in the exit region of an upper-level jet

Author

Brill, K. F, Uccellini, L. W, Burkhart, R. P, Warner, T. T, and Anthes, R. A

Subjects
Meteorology And Climatology
Abstract

A numerical study was performed of a severe weather event (tornado) which occurred on May 10, 1973 in the Ohio region. The situation was modeled with a primitive equation mesoscale dynamic formulation. Account was taken of precipitation, the planetary boundary layer parameters as bulk quantities, the vertical pressure gradient, and lateral boundary conditions based on radiosonde data. Two 12-hr simulations, adiabatic and nondivergent, respectively, were analyzed for relationships between upper and lower level jets. In the adiabatic formulation, a transverse circulation with a low level jet formed at the exit region of the upper level jet. The nondivergent situation led to similar, but weaker, phenomena. Both forms suggest that indirect circulation in the exit zone of an upper level jet is strongly influenced by the initial structure of the jet.

Published
1985
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198. The impact of data density and data error on the evolution of mesoscale forecast error

Author

Warner, T. T and Key, L. E

Subjects
Meteorology And Climatology
Abstract

The effects of data density and data errors on the accuracy of mesoscale weather forecasts were assessed by simulations of a period in February 1979 when a snowstorm occurred along the U.S. eastern seaboard. The simulations were initiated every 12 hr and the growth of the rms error was tracked as a function of time and varying data densities. A uniform grid of instrumentation separation and perfect boundary conditions were assumed for all the simulations. A bias error representation was defined to account for systematic measurement errors. A brief summary of features of the somewhat complex storm is provided, together with the parameters of the 11 different simulations with high, medium and low data densities. The accuracy of the forecasts were proportional to the data density, although the error decreased for all the simulations over a 24 hr period. The density of the vertical data had a significant impact on the accuracy of the forecast, whereas the horizontal data density did not. Finally, pathways by which errors were transferred among variables were identified.

Published
1985

199. Dynamic and static initialization of a mesoscale model using VAS satellite data

Author

Beauchamp, J. G and Warner, T. T

Subjects
Meteorology And Climatology
Abstract

Various mesoscale weather forecast model initialization procedures were tested in seven simulation forecasts for a 12 hr period in July 1981. Attention was given to the impacts of using as input radiosonde data, VISSR Atmospheric Sounder (VAS) data and a combination of VAS and data from a smoothed global analysis. The data were assimilated with successive correction objective analysis procedures. The model had a 60 km horizontal grid-length resolution, 14 layers in the vertical, and accounted for short- and long-wave energy in the surface energy budget but not in the atmosphere. Conventional data were used for the mass and moisture fields. The trials showed that VAS data enhanced the predictions of the temperature and mass variables, while winds were least accurately predicted when VAS data were entered in the initializations. Finally, statically initialized precipitation forecasts from radiosonde and/or VAS data exhibited equal skill.

Published
1985

200. The error associated with use of various forms of the divergence equation to diagnose geopotential and temperature

Author

Modica, G. M and Warner, T. T

Subjects
Meteorology And Climatology
Abstract

An experimental study was made of errors arising from diagnosing the geopotential and temperature for numerical weather prediction models by means of an inviscid divergence equation (DE). The experiment consisted of a simulation of a snow storm which occurred in 1979, with observational data being input for every point of the model grid and for the geopotential boundary condition, thereby eliminating errors in the horizontal and vertical analysis. The DE terms were recorded at each grid point, and were found to include synoptic-scale geopotential height errors up to 23 m and rms temperature errors exceeding 26 C in the PBL. The errors were minimal above 800 mb. The various unsuccessful attempts to reduce or eliminate the errors are described.

Published
1985

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