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155. Toward a Flexible Metadata Pipeline for Fish Specimen Images

Author

Jebbia, Dom, Wang, Xiaojun, Bakis, Yasin, Bart Jr., Henry L., Greenberg, Jane, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Garoufallou, Emmanouel, editor, and Vlachidis, Andreas, editor

Published
2023
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156. Research on the Selection of Cognitive Status Test Items and Indicators for Workers in Confined Spaces

Author

Wang, Chuan, Wang, Ting, Chen, Yi, Wang, Xiaojun, Wang, Ziying, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Long, Shengzhao, editor, and Dhillon, Balbir S., editor

Published
2023
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157. Research on the Evaluation of Abnormal Cognitive Status of Workers in Confined Spaces

Author

Wang, Chuan, Zhou, Qianxiang, Wang, Xiaojun, Wang, Ziying, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Long, Shengzhao, editor, and Dhillon, Balbir S., editor

Published
2023
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158. Impaired glycine neurotransmission causes adolescent idiopathic scoliosis

Author

Wang, Xiaolu, Yue, Ming, Cheung, Jason Pui Yin, Cheung, Prudence Wing Hang, Fan, Yanhui, Wu, Meicheng, Wang, Xiaojun, Zhao, Sen, Khanshour, Anas M., Rios, Jonathan J., Chen, Zheyi, Wang, Xiwei, Tu, Wenwei, Chan, Danny, Yuan, Qiuju, Qin, Dajiang, Qiu, Guixing, Wu, Zhihong, Zhang, Terry Jianguo, Ikegawa, Shiro, Wu, Nan, Wise, Carol A., Hu, Yong, Luk, Keith Dip Kei, Song, You-Qiang, and Gao, Bo

Subjects
Neural transmission -- Health aspects, Scoliosis -- Causes of -- Development and progression, Glycine -- Health aspects, Health care industry
Abstract

Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity, affecting millions of adolescents worldwide, but it lacks a defined theory of etiopathogenesis. Because of this, treatment of AIS is limited to bracing and/ or invasive surgery after onset. Preonset diagnosis or preventive treatment remains unavailable. Here, we performed a genetic analysis of a large multicenter AIS cohort and identified disease- causing and predisposing variants of SLC6A9 in multigeneration families, trios, and sporadic patients. Variants of SLC6A9, which encodes glycine transporter 1 (GLYT1), reduced glycine-uptake activity in cells, leading to increased extracellular glycine levels and aberrant glycinergic neurotransmission. Slc6a9 mutant zebrafish exhibited discoordination of spinal neural activities and pronounced lateral spinal curvature, a phenotype resembling human patients. The penetrance and severity of curvature were sensitive to the dosage of functional glyt1. Administration of a glycine receptor antagonist or a clinically used glycine neutralizer (sodium benzoate) partially rescued the phenotype. Our results indicate a neuropathic origin for 'idiopathic' scoliosis, involving the dysfunction of synaptic neurotransmission and central pattern generators (CPGs), potentially a common cause of AIS. Our work further suggests avenues for early diagnosis and intervention of AIS in preadolescents., Introduction Adolescent idiopathic scoliosis (AIS) is a condition in which the spine is deformed with a lateral curvature exceeding 10 degrees in otherwise healthy adolescents (1, 2). With a prevalence [...]

Published
2024
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198. Highly-robust reentrant superconductivity in CsV3Sb5 under pressure

Author

Chen, Xu, Zhan, Xinhui, Wang, Xiaojun, Deng, Jun, Liu, Xiao-bing, Chen, Xin, Guo, Jian-gang, and Chen, Xiaolong

Subjects
Condensed Matter - Superconductivity
Abstract

Here we present the superconducting property and structural stability of kagome CsV3Sb5 under in-situ high pressures. For the initial SC-I phase, its Tc is quickly enhanced from 3.5 K to 7.6 K and then totally suppressed at P~10 GPa. Further increasing the applied pressures, an SC-II phase emerges at P~15 GPa and persists up to 100 GPa. The Tc rapidly increases to the maximal value of 5.2 K at P=53.6 GPa and rather slowly decreases to 4.7 K at P=100 GPa. A two-dome-like variation of Tc in CsV3Sb5 is concluded here. The Raman measurements demonstrate that weakening of E2g model and strengthening of A1g model occur without phase transition as entering the SC-II phase, which is supported by the results of phonon spectra calculations. Electronic structure calculations reveal that exertion of pressure may bridge the gap of topological surface nontrivial states near EF, i. e. Z2 invariant. Meanwhile, it enlarges Fermi surface significantly, consistent with the increased carrier density. The findings here point out the change of electronic structure and strengthened electron-phonon coupling should be responsible for the pressure-induced reentrant SC., Comment: 10 pages, 4 figures

Published
2021
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