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599 results on '"Valle, Giorgio"'

158. A deep survey of alternative splicing in grape reveals changes in the splicing machinery related to tissue, stress condition and genotype

Author

Vitulo, Nicola, primary, Forcato, Claudio, additional, Carpinelli, Elisa Corteggiani, additional, Telatin, Andrea, additional, Campagna, Davide, additional, D'Angelo, Michela, additional, Zimbello, Rosanna, additional, Corso, Massimiliano, additional, Vannozzi, Alessandro, additional, Bonghi, Claudio, additional, Lucchin, Margherita, additional, and Valle, Giorgio, additional

Published
2014
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161. RNA Sequencing of the Exercise Transcriptome in Equine Athletes

Author

Capomaccio, Stefano, primary, Vitulo, Nicola, additional, Verini-Supplizi, Andrea, additional, Barcaccia, Gianni, additional, Albiero, Alessandro, additional, D'Angelo, Michela, additional, Campagna, Davide, additional, Valle, Giorgio, additional, Felicetti, Michela, additional, Silvestrelli, Maurizio, additional, and Cappelli, Katia, additional

Published
2013
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164. A database of transcripts expressed in human skeletal muscle

Author

Valle, Giorgio, Toppo, S., Cannata, N., Pallavicini, A., Laveder, P., Ievolella, C., Stanchi, F., Pacchioni, B., Trevisan, S., Salamon, M., Bortoletto, G., Dioguardi, R., Scannapieco, P., Frigimelica, E., Zimbello, R., Simionati, B., and Lanfranchi, Gerolamo

Published
2000

165. Multi-Tasking Role of the Mechanosensing Protein Ankrd2 in the Signaling Network of Striated Muscle

Author

Belgrano, Anna, Rakićević, Ljiljana, Mittempergher, Lorenza, Campanaro, Stefano, Martinelli, Valentina C., Mouly, Vincent, Valle, Giorgio, Kojić, Snežana, Faulkner, Georgine, Belgrano, Anna, Rakićević, Ljiljana, Mittempergher, Lorenza, Campanaro, Stefano, Martinelli, Valentina C., Mouly, Vincent, Valle, Giorgio, Kojić, Snežana, and Faulkner, Georgine

Abstract

Background: Ankrd2 (also known as Arpp) together with Ankrd1/CARP and DARP are members of the MARP mechanosensing proteins that form a complex with titin (N2A)/calpain 3 protease/myopalladin. In muscle, Ankrd2 is located in the I-band of the sarcomere and moves to the nucleus of adjacent myofibers on muscle injury. In myoblasts it is predominantly in the nucleus and on differentiation shifts from the nucleus to the cytoplasm. In agreement with its role as a sensor it interacts both with sarcomeric proteins and transcription factors. Methodology/Principal Findings: Expression profiling of endogenous Ankrd2 silenced in human myotubes was undertaken to elucidate its role as an intermediary in cell signaling pathways. Silencing Ankrd2 expression altered the expression of genes involved in both intercellular communication (cytokine-cytokine receptor interaction, endocytosis, focal adhesion, tight junction, gap junction and regulation of the actin cytoskeleton) and intracellular communication (calcium, insulin, MAPK, p53, TGF-beta and Wnt signaling). The significance of Ankrd2 in cell signaling was strengthened by the fact that we were able to show for the first time that Nkx2.5 and p53 are upstream effectors of the Ankrd2 gene and that Ankrd1/CARP, another MARP member, can modulate the transcriptional ability of MyoD on the Ankrd2 promoter. Another novel finding was the interaction between Ankrd2 and proteins with PDZ and SH3 domains, further supporting its role in signaling. It is noteworthy that we demonstrated that transcription factors PAX6, LHX2, NFIL3 and MECP2, were able to bind both the Ankrd2 protein and its promoter indicating the presence of a regulatory feedback loop mechanism. Conclusions/Significance: In conclusion we demonstrate that Ankrd2 is a potent regulator in muscle cells affecting a multitude of pathways and processes.

Published
2011

171. The DNA sequence of cosmid 14-13b from chromosome XIV of S. cerevisiae reveals an unusually high number of overlapping ORFs

Author

DE ANTONI, A., D'Angelo, M., DAL PERO, F., Sartorello, F., Pallavicini, A., Pandolfo, D., Lanfranchi, Gerolamo, Valle, Giorgio, DE ANTONI, A., D'Angelo, M., DAL PERO, F., Sartorello, F., Pallavicini, Alberto, Pandolfo, D., Lanfranchi, G., and Valle, G.

Subjects
genome sequencing, Yeast
Abstract

This work is part of the effort for sequencing chromosome XIV of Saccharomyces cerevisiae. Cosmid 14-13b contains a 37.8 kb insert derived from a partial Sau3A digestion of the genome, cloned into the BamHI site of the vector Pou6. The strategy used for sequencing is based on the fragmentation of the whole cosmid by sonication, followed by shotgun sequencing on an Applied Biosystem DNA sequencer. The clones with inserts corresponding to the vector were identified by dot-blot hybridization, without the need of sequencing. The analysis of the DNA sequence reveals 29 open reading frames (ORFs) longer than 300 bases. Nine ORFs are internal to some other ORFs. Similarity searches against DNA and protein data banks show that six ORFs correspond to already known yeast genes (OMP1, PSU1, MLS1, RPC19, DBP2, CYB5) and one ORF matches the sequence of a putative yeast gene (ESBP6).

Published
1997

174. First Survey of the Wheat Chromosome 5A Composition through a Next Generation Sequencing Approach

Author

Vitulo, Nicola, primary, Albiero, Alessandro, additional, Forcato, Claudio, additional, Campagna, Davide, additional, Dal Pero, Francesca, additional, Bagnaresi, Paolo, additional, Colaiacovo, Moreno, additional, Faccioli, Primetta, additional, Lamontanara, Antonella, additional, Šimková, Hana, additional, Kubaláková, Marie, additional, Perrotta, Gaetano, additional, Facella, Paolo, additional, Lopez, Loredana, additional, Pietrella, Marco, additional, Gianese, Giulio, additional, Doležel, Jaroslav, additional, Giuliano, Giovanni, additional, Cattivelli, Luigi, additional, Valle, Giorgio, additional, and Stanca, A. Michele, additional

Published
2011
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178. Physical mapping in highly heterozygous genomes: a physical contig map of the Pinot Noir grapevine cultivar

Author

Scalabrin, Simone, primary, Troggio, Michela, additional, Moroldo, Marco, additional, Pindo, Massimo, additional, Felice, Nicoletta, additional, Coppola, Giuseppina, additional, Prete, Giacomo, additional, Malacarne, Giulia, additional, Marconi, Raffaella, additional, Faes, Giorgia, additional, Jurman, Irena, additional, Grando, Stella, additional, Jesse, Taco, additional, Segala, Cinzia, additional, Valle, Giorgio, additional, Policriti, Alberto, additional, Fontana, Paolo, additional, Morgante, Michele, additional, and Velasco, Riccardo, additional

Published
2010
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179. Erratum to: High throughput approaches reveal splicing of primary microRNA transcripts and tissue specific expression of mature microRNAs in Vitis vinifera

Author

Mica, Erica, primary, Piccolo, Viviana, additional, Delledonne, Massimo, additional, Ferrarini, Alberto, additional, Pezzotti, Mario, additional, Casati, Cesare, additional, Del Fabbro, Cristian, additional, Valle, Giorgio, additional, Policriti, Alberto, additional, Morgante, Michele, additional, Pesole, Graziano, additional, Pè, M Enrico, additional, and Horner, David S, additional

Published
2010
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181. Functional profiling of the Saccharomyces cerevisiae genome.

Author

UCL - SST/ISV - Institut des sciences de la vie, Giaever, Guri, Chu, Angela M, Ni, Li, Connelly, Carla, Riles, Linda, Véronneau, Steeve, Dow, Sally, Lucau-Danila, Ankuta, Anderson, Keith, André, Bruno, Arkin, Adam P, Astromoff, Anna, El-Bakkoury, Mohamed, Bangham, Rhonda, Benito, Rocio, Brachat, Sophie, Campanaro, Stefano, Curtiss, Matt, Davis, Karen, Deutschbauer, Adam, Entian, Karl-Dieter, Flaherty, Patrick, Foury, Françoise, Garfinkel, David J, Gerstein, Mark, Gotte, Deanna, Güldener, Ulrich, Hegemann, Johannes H, Hempel, Svenja, Herman, Zelek, Jaramillo, Daniel F, Kelly, Diane E, Kelly, Steven L, Kötter, Peter, LaBonte, Darlene, Lamb, David C, Lan, Ning, Liang, Hong, Liao, Hong, Liu, Lucy, Luo, Chuanyun, Lussier, Marc, Mao, Rong, Menard, Patrice, Ooi, Siew Loon, Revuelta, Jose L, Roberts, Christopher J, Rose, Matthias, Ross-Macdonald, Petra, Scherens, Bart, Schimmack, Greg, Shafer, Brenda, Shoemaker, Daniel D, Sookhai-Mahadeo, Sharon, Storms, Reginald K, Strathern, Jeffrey N, Valle, Giorgio, Voet, Marleen, Volckaert, Guido, Wang, Ching-yun, Ward, Teresa R, Wilhelmy, Julie, Winzeler, Elizabeth A, Yang, Yonghong, Yen, Grace, Youngman, Elaine, Yu, Kexin, Bussey, Howard, Boeke, Jef D, Snyder, Michael, Philippsen, Peter, Davis, Ronald W, Johnston, Mark, UCL - SST/ISV - Institut des sciences de la vie, Giaever, Guri, Chu, Angela M, Ni, Li, Connelly, Carla, Riles, Linda, Véronneau, Steeve, Dow, Sally, Lucau-Danila, Ankuta, Anderson, Keith, André, Bruno, Arkin, Adam P, Astromoff, Anna, El-Bakkoury, Mohamed, Bangham, Rhonda, Benito, Rocio, Brachat, Sophie, Campanaro, Stefano, Curtiss, Matt, Davis, Karen, Deutschbauer, Adam, Entian, Karl-Dieter, Flaherty, Patrick, Foury, Françoise, Garfinkel, David J, Gerstein, Mark, Gotte, Deanna, Güldener, Ulrich, Hegemann, Johannes H, Hempel, Svenja, Herman, Zelek, Jaramillo, Daniel F, Kelly, Diane E, Kelly, Steven L, Kötter, Peter, LaBonte, Darlene, Lamb, David C, Lan, Ning, Liang, Hong, Liao, Hong, Liu, Lucy, Luo, Chuanyun, Lussier, Marc, Mao, Rong, Menard, Patrice, Ooi, Siew Loon, Revuelta, Jose L, Roberts, Christopher J, Rose, Matthias, Ross-Macdonald, Petra, Scherens, Bart, Schimmack, Greg, Shafer, Brenda, Shoemaker, Daniel D, Sookhai-Mahadeo, Sharon, Storms, Reginald K, Strathern, Jeffrey N, Valle, Giorgio, Voet, Marleen, Volckaert, Guido, Wang, Ching-yun, Ward, Teresa R, Wilhelmy, Julie, Winzeler, Elizabeth A, Yang, Yonghong, Yen, Grace, Youngman, Elaine, Yu, Kexin, Bussey, Howard, Boeke, Jef D, Snyder, Michael, Philippsen, Peter, Davis, Ronald W, and Johnston, Mark

Abstract

Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete collection of gene-deletion mutants (96% of annotated open reading frames, or ORFs) of the yeast Saccharomyces cerevisiae. DNA sequences dubbed 'molecular bar codes' uniquely identify each strain, enabling their growth to be analysed in parallel and the fitness contribution of each gene to be quantitatively assessed by hybridization to high-density oligonucleotide arrays. We show that previously known and new genes are necessary for optimal growth under six well-studied conditions: high salt, sorbitol, galactose, pH 8, minimal medium and nystatin treatment. Less than 7% of genes that exhibit a significant increase in messenger RNA expression are also required for optimal growth in four of the tested conditions. Our results validate the yeast gene-deletion collection as a valuable resource for functional genomics.

Published
2002

183. High throughput approaches reveal splicing of primary microRNA transcripts and tissue specific expression of mature microRNAs in Vitis vinifera

Author

Mica, Erica, primary, Piccolo, Viviana, additional, Delledonne, Massimo, additional, Ferrarini, Alberto, additional, Pezzotti, Mario, additional, Casati, Cesare, additional, Del Fabbro, Cristian, additional, Valle, Giorgio, additional, Policriti, Alberto, additional, Morgante, Michele, additional, Pesole, Graziano, additional, Pè, M Enrico, additional, and Horner, David S, additional

Published
2009
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185. Muscle Research and Gene Ontology: New standards for improved data integration

Author

Feltrin, Erika, primary, Campanaro, Stefano, additional, Diehl, Alexander D, additional, Ehler, Elisabeth, additional, Faulkner, Georgine, additional, Fordham, Jennifer, additional, Gardin, Chiara, additional, Harris, Midori, additional, Hill, David, additional, Knoell, Ralph, additional, Laveder, Paolo, additional, Mittempergher, Lorenza, additional, Nori, Alessandra, additional, Reggiani, Carlo, additional, Sorrentino, Vincenzo, additional, Volpe, Pompeo, additional, Zara, Ivano, additional, Valle, Giorgio, additional, and Deegan née Clark, Jennifer, additional

Published
2009
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186. Characterization of Human Skeletal Muscle Ankrd2

Author

Pallavicini, Alberto, Kojić, Snežana, Bean, Camilla, Vainzof, Mariz, Salamon, Michela, Ievolella, Chiara, Bortoletto, Gladis, Pacchioni, Beniamima, Zatz, Mayana, Lanfranchi, Gerolamo, Faulkner, Georgine, Valle, Giorgio, Pallavicini, Alberto, Kojić, Snežana, Bean, Camilla, Vainzof, Mariz, Salamon, Michela, Ievolella, Chiara, Bortoletto, Gladis, Pacchioni, Beniamima, Zatz, Mayana, Lanfranchi, Gerolamo, Faulkner, Georgine, and Valle, Giorgio

Abstract

Human Ankrd2 transcript encodes a 37-kDa protein that is similar to mouse Ankrd2 recently shown to be involved in hypertrophy of skeletal muscle. These novel ankyrin-rich proteins are related to C-193/CARP/MARP, a cardiac protein involved in the control of cardiac hypertrophy. A human genomic region of 14,300 bp was sequenced revealing a gene organization similar to mouse Ankrd2 with nine exons, four of which encode ankyrin repeats. The intracellular localization of Ankrd2 was unknown since no protein studies had been reported. In this paper we studied the intracellular localization of the protein and its expression on differentiation using polyclonal and monoclonal antibodies produced to human Ankrd2. In adult skeletal muscle Ankrd2 is found in slow fibers; however, not all of the slow fibers express Ankrd2 at the same level. This is particularly evident in dystrophic muscles, where the expression of Ankrd2 in slow fibers seems to be severely reduced.

Published
2001

190. Annotating genomes with massive-scale RNA sequencing

Author

Denoeud, France, primary, Aury, Jean-Marc, additional, Da Silva, Corinne, additional, Noel, Benjamin, additional, Rogier, Odile, additional, Delledonne, Massimo, additional, Morgante, Michele, additional, Valle, Giorgio, additional, Wincker, Patrick, additional, Scarpelli, Claude, additional, Jaillon, Olivier, additional, and Artiguenave, François, additional

Published
2008
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191. The complete sequence of the yeast chromosome III

Author

Oliver, S. G., van der Aart, Q. J. M., Agostoni Carbone, M. L., Aigle, M., Alberghina, L., Alexandraki, D., Antoine, G., Anwar, R., Ballesta, J. P. G., Benit, P., Berben, G., Bergantino, Elisabetta, Biteau, N., Bolle, P. A., Bolotin Fukuhara, M., Brown, A., Brown, A. J. P., Buhler, J. M., Carcano, C., Carignani, G., Cederberg, H., Chanet, R., Contreras, R., Crouzet, M., Daignan Fornier, B., Defoor, E., Delgado, M., Demolder, J., Doira, C., Dubois, E., Dujon, B., Dusterhoft, A., Erdmann, D., Esteban, M., Fabre, F., Fairhead, C., Faye, G., Feldmann, H., Fiers, W., Francingues Gaillard, M. C., Franco, L., Frontali, L., Fukuhara, H., Fuller, L. J., Galland, P., Gent, M. E., Gigot, D., Gilliquet, V., Glansdorff, N., Goffeau, A., Grenson, M., Grisanti, P., Grivell, L. A., de Haan, M., Haasemann, M., Hatat, D., Hoenicka, J., Hegemann, J., Herbert, C. J., Hilger, F., Hohmann, S., Hollenberg, C. P., Huse, K., Iborra, F., Indje, K. J., Isono, K., Jacq, C., Jacquet, M., James, C. M., Jauniaux, J. C., Jia, Y., Jimenez, A., Kelly, A., Kleinhans, U., Kreisl, P., Lanfranchi, Gerolamo, Lewis, C, Vanderlinden, C. G., Lucchini, G., Lutzenkirchen, K, Maat, M. J., Mallet, L., Mannhaupet, G., Martegani, E., Mathieu, A., Maurer, C. T. C., Mcconnell, D., Mckee, R. A., Messenguy, F., Mewes, H. W., Molemans, F., Montague, M. A., Muzi Falconi, M., Navas, L., Newlon, C. S., Noone, D., Pallier, C., Panzeri, L., Pearson, B. M., Perea, J., Philippsen, P., Pierard, A., Planta, R. J., Plevani, P., Poetsch, B., Pohl, F., Purnelle, B., Ramezani Rad, M., Rasmussen, S. W., Raynal, A., Remacha, M., Richterich, P., Roberts, A. B., Rodriguez, F., Sanz, E., Schaaff Gerstenschlager, I., Scherens, B., Schweitzer, B., Shu, Y., Skala, J., Slonimski, P. P., Sor, F., Soustelle, C., Spiegelberg, R., Stateva, L. I., Steensma, S., Steiner, H. Y., Thierry, A., Thireos, G., Tzermia, M., Urrestarazu, L. A., Valle, Giorgio, Vetter, I., van Vliet Reedijk, J. C., Voet, M., Volckaert, G., Vreken, P., Wang, H., Warmington, J. R., von Wettstein, D., Wicksteed, B. L., Wilson, C., Wurst, H., Xu, G., Yoshikawa, A., Zimmermann, F. K., and Sgouros, J. G.

Published
1992

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