987 results on '"Trigo, M."'
Search Results
152. Feasibility and reliability of the Assessing Levels of Physical Activity health‐related fitness test battery in adults with intellectual disabilities
- Author
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Cabeza‐Ruiz, R., primary, Sánchez‐López, A. M., additional, Trigo, M. E., additional, and Gómez‐Píriz, P. T., additional
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- 2020
- Full Text
- View/download PDF
153. Discovery of a thermonuclear Type I X-ray burst in infrared: new limits on the orbital period of 4U 1728-34
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Vincentelli, F M, primary, Cavecchi, Y, primary, Casella, P, primary, Migliari, S, primary, Altamirano, D, primary, Belloni, T, primary, and Diaz-Trigo, M, primary
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- 2020
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154. Analysis of the internet use and students' Web 2.0 digital competence in a Russian university
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Lopez, Ruth Martinez, primary, Domínguez, Carmen Yot, additional, and Trigo, M. Eva, additional
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- 2020
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155. Ultrafast Acoustic Phonon Dynamics in the Weyl Semimetal TaAs Probed by Time-Resolved X-ray Diffraction
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Lee, Min-Cheol, primary, Sirica, N., additional, Teitelbaum, S. W., additional, Maznev, A., additional, de la Pena Munoz, G. A., additional, Krapivin, V., additional, Huang, Y., additional, Shi, J., additional, Tutchton, R., additional, Zhu, J.-X., additional, Zhao, L. X., additional, Chen, G. F., additional, Xu, B., additional, Yang, R., additional, Qiu, X. G., additional, Yarotski, D. A., additional, Nelson, K. A., additional, Trigo, M., additional, Reis, D. A., additional, and Prasankumar, R. P., additional
- Published
- 2020
- Full Text
- View/download PDF
156. Simultaneous detection of an intrinsic absorber and a compact jet emission in the X-ray binary IGR J17091−3624 during a hard accretion state
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Gatuzz, E, primary, Díaz Trigo, M, additional, Miller-Jones, J C A, additional, and Migliari, S, additional
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- 2019
- Full Text
- View/download PDF
157. Carcinoma basocelular agresivo del párpado inferior: ventaja del vismodegib neoadyuvante
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Monteiro, A.F., primary, Rato, M., additional, Trigo, M., additional, and Martins, C., additional
- Published
- 2019
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158. New Science Opportunities Enabled by LCLS-II X-Ray Lasers
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Abbamonte, P., primary, Abild-Pedersen, Frank, additional, Adams, P., additional, Ahmed, M., additional, Albert, F., additional, Mori, R., additional, Anfinrud, P., additional, Aquila, A., additional, Armstrong, M., additional, Arthur, J., additional, Bargar, J., additional, Barty, A., additional, Bergmann, U., additional, Berrah, N., additional, Blaj, G., additional, Bluhm, H., additional, Bolme, C., additional, Bostedt, C., additional, Boutet, S., additional, Brown, G., additional, Bucksbaum, P., additional, Cargnello, M., additional, Carini, G., additional, Cavalleri, A., additional, Cherezov, V., additional, Chiu, W., additional, Chuang, Y., additional, Cocco, D., additional, Coffee, R., additional, Collins, G., additional, Cordones-Hahn, A., additional, Cryan, J., additional, Dakovski, G., additional, Dantus, M., additional, Demirci, H., additional, Denes, P., additional, Devereaux, T., additional, Ding, Y., additional, Doniach, S., additional, Dorner, R., additional, Dunne, M., additional, Durr, H., additional, Egami, T., additional, Eisenberg, D., additional, Emma, P., additional, Fadley, C., additional, Falcone, R., additional, Feng, Y., additional, Fischer, P., additional, Fiuza, F., additional, Fletcher, L., additional, Foucar, L., additional, Frank, M., additional, Fraser, J., additional, Frei, H., additional, Fritz, D., additional, Fromme, P., additional, Fry, A., additional, Fuchs, M., additional, Fuoss, P., additional, Gaffney, K., additional, Gamboa, E., additional, Gessner, O., additional, Ghimire, S., additional, Gleason, A., additional, Glenzer, S., additional, Gorkhover, T., additional, Gray, A., additional, Guehr, M., additional, Guo, J., additional, Hajdu, J., additional, Hansen, S., additional, Hart, P., additional, Hashimoto, M., additional, Hastings, J., additional, Haxton, D., additional, Heimann, P., additional, Heinz, T., additional, Hexemer, A., additional, Hill, J., additional, Himpsel, F., additional, Ho, P., additional, Hogue, B., additional, Huang, Z., additional, Hunter, M., additional, Hura, G., additional, Huse, N., additional, Hussain, Z., additional, Ilchen, M., additional, Jacobsen, C., additional, Kenney, C., additional, Kern, J., additional, Kevan, S., additional, Kim, J., additional, Kim, H., additional, Kirchmann, P., additional, Kirian, R., additional, Kivelson, S., additional, Kliewer, C., additional, Koralek, J., additional, Kovacsova, G., additional, Lanzara, A., additional, LaRue, J., additional, Lee, H., additional, Lee, J., additional, Lee, W., additional, Lee, Y., additional, Lindau, I., additional, Lindenberg, A., additional, Liu, Z., additional, Lu, D., additional, Lundstrom, U., additional, MacDowell, A., additional, Mao, W., additional, Marangos, J., additional, Marcus, G., additional, Martinez, T., additional, McCurdy, W., additional, McDermott, G., additional, McGuffey, C., additional, Minitti, M., additional, Miyabe, S., additional, Moeller, S., additional, Moore, R., additional, Mukamel, S., additional, Nass, K., additional, Natan, A., additional, Nelson, K., additional, Nemsak, S., additional, Neumark, D., additional, Neutze, R., additional, Nilsson, A., additional, Nordlund, D., additional, Norskov, J., additional, Nozawa, S., additional, Ogasawara, H., additional, Ohldag, H., additional, Orville, A., additional, Osborn, D., additional, Osipov, T., additional, Ourmazd, A., additional, Parkinson, D., additional, Pellegrini, C., additional, Phillips, G., additional, Rasing, T., additional, Raubenheimer, T., additional, Recigno, T., additional, Reid, A., additional, Reis, D., additional, Robert, A., additional, Robinson, J., additional, Rolles, D., additional, Rost, J., additional, Roy, S., additional, Rudenko, A., additional, Russell, T., additional, Sandberg, R., additional, Sandhu, A., additional, Sauter, N., additional, Schlichting, I., additional, Schlogl, R., additional, Schlotter, W., additional, Schmidt, M., additional, Schneider, J., additional, Schoenlein, R., additional, Schoeffler, M., additional, Scholl, A., additional, Shen, Z., additional, Shpyrko, O., additional, Silva, T., additional, Sinha, S., additional, Slaughter, D., additional, Sobota, J., additional, Sokaras, D., additional, Sokolowski-Tinten, K., additional, Southworth, S., additional, Spence, J., additional, Stan, C., additional, Stohr, J., additional, Stroud, R., additional, Sundstrom, V., additional, Taatjes, C., additional, Thomas, A., additional, Trigo, M., additional, Tsui, Y., additional, Turner, J., additional, van Buuren, A., additional, Vinko, S., additional, Wakatsuki, S., additional, Wark, J., additional, Weber, P., additional, Weber, T., additional, Wei, M., additional, Weiss, T., additional, Wernet, P., additional, White, W., additional, Willmott, P., additional, Wilson, K., additional, Wurth, W., additional, Yachandra, V., additional, Yano, J., additional, Yarotski, D., additional, Young, L., additional, Zhu, Y., additional, Zhu, D., additional, and Zwart, P., additional
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- 2015
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159. Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals
- Author
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Roc, L., de Mendoza, C., Fernandez-Alonso, M., Reina, G., Soriano, V., Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M.D., Caballero, E., Molina, I., Aguilera, A., Rodriguez-Calvino, J.J., Navarro, D., Rivero, C., Vilarino, M.D., Benito, R., Algarate, S., Gil, J., de Lejarazu, R.O., Rojo, S., Eiros, J.M., San Miguel, A., Manzardo, C., Miro, J.M., Garcia, J., Paz, I., Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Rodriguez-Iglesias, M., Hernandez-Betancor, A., Martin, A.M., Ramos, J.M., Gimeno, A., Gutierrez, F., Rodriguez, J.C., Sanchez, V., Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A.M., Gomez-Sirvent, J.L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J.L., Penaranda, M., Hernaez-Crespo, S., Montejo, J.M., Martinez-Sapina, A., Viciana, I., Cabezas, T., Lozano, A., Fernandez, J.M., Garcia-Bermejo, I., Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I., Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I., Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gutierrez, L., Cuervas-Mons, V., Barreiro, P., Corral, O., and Gomez-Gallego, F.
- Abstract
Two kidney transplant recipients from a single donor became infected with HTLV-1 (human T-lymphotropic virus type 1) in Spain. One developed myelopathy 8 months following surgery despite early prescription of antiretroviral therapy. The allograft was removed from the second recipient at month 8 due to rejection and immunosuppressors discontinued. To date, 3 years later, this patient remains infected but asymptomatic. HTLV-1 infection was recognized retrospectively in the donor, a native Spaniard who had sex partners from endemic regions. Our findings call for a reappraisal of screening policies on donor-recipient organ transplantation. Based on the high risk of disease development and the large flux of persons from HTLV-1 endemic regions, pre-transplant HTLV-1 testing should be mandatory in Spain.
- Published
- 2019
160. The Effect of Wheat Bran on the Total Apparent Digestibility of Dry Matter, NDF, ADF and CP in Goat Diets
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Arias, R., G. Muro, M., S. Trigo, M., Eirin, M., Boyezuk, D., and A. Cordiviola, C.
- Subjects
food and beverages - Abstract
The aim of this study was to evaluate the effect of wheat bran in increasing amounts on the total apparent dry matter digestibility (DM), the fiber (NDF, ADF) and the protein (CP) in goat diets. Eight Criollo x Nubian goats were used in a 4x4 Latin square experimental design. Four diets were provided: alfalfa hay (D0); alfalfa hay + wheat bran (WB) (0.5% of BW/day) (D1), alfalfa hay + WB (1% of BW/day) (D2) and alfalfa hay + WB (1.5% of BW/day) (D3). All the treatments consisted of alfalfa hay delivered ad libitum. In vivo total apparent digestibility of the DM intake and its fractions was calculated as a result of the difference between the ingested and excreted amounts in relation to the intake. Forage intake and the relation forage/concentrate decreased linearly (p < 0.05) with the increase of the concentrate. Energy intake increased linearly (p < 0.05) with larger amounts of WB. The total apparent digestibility of the ingested DM showed a significant linear increase (p < 0.05) with the increase of concentrate. The digestibility of NDF, ADF and CP registered no differences (p > 0.05) with the WB increase in the different treatments. We can conclude that the addition of WB in Criollo x Nubian goats improved the total apparent digestibility of the ingested DM by replacing hay for concentrate, without altering NDF, ADF and CP fractions.Read Complete Article at ijSciences: V82019092182 AND DOI: http://dx.doi.org/10.18483/ijSci.2182
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- 2019
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161. HTLV-1 infection in solid organ transplant donors and recipients in Spain
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de Mendoza, Carmen, Roc, Lourdes, Benito, Rafael, Reina, Gabriel, Manuel Ramos, Jose, Gomez, Cesar, Aguilera, Antonio, Rodriguez-Iglesias, Manuel, Garcia-Costa, Juan, Fernandez-Alonso, Miriam, Soriano, Vicente, Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M. D., Caballero, E., Molina, I., Rodriguez-Calvino, J. J., Navarro, D., Rivero, C., Vilarino, M. D., Algarate, S., Gil, J., Ortiz de Lejarazu, R., Rojo, S., Eiros, J. M., San Miguel, A., Manzardo, C., Miro, J. M., Garcia, J., Paz, I., Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Hernandez-Betancor, A., Martin, A. M., Gimeno, A., Gutierrez, F., Rodriguez, J. C., Sanchez, V., Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A. M., Gomez-Sirvent, J. L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J. L., Penaranda, M., Hernaez-Crespo, S., Montejo, J. M., Martinez-Sapina, A., Viciana, I., Cabezas, T., Lozano, A., Fernandez, J. M., Garcia-Bermejo, I., Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I., Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I., Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gu-tierrez, L., Cuervas-Mons, V., Barreiro, P., Soriano, V., Corral, O., Gomez-Gallego, F., Spanish HTLV Network, Bioquímica y Biología Molecular, Microbiología, Medicina Preventiva, Salud Pública, Soriano, Vicente [0000-0002-4624-5199], Soriano, Vicente, [Mendoza C] Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Universidad CEU-San Pablo, Madrid, Spain. [Roc L] Hospital Miguel Servet, Zaragoza, Spain. [Benito R] Hospital Lozano Blesa, Zaragoza, Spain. [Reina G] Clínica Universitaria de Navarra, Pamplona, Spain. [Ramos JM] Hospital General Universitario, Alicante, Spain. [Gómez C] Complejo Hospitalario, Toledo, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
0301 basic medicine ,2420 Virología ,medicine.medical_treatment ,humanos ,Myelopathy ,Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies::Retrospective Studies [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,0302 clinical medicine ,Medical microbiology ,Tropical spastic paraparesis ,Infeccions per retrovirus ,030212 general & internal medicine ,Trasplantació d'òrgans, teixits, etc - Espanya ,mediana edad ,anciano ,Leukemia ,Leucèmia ,Immunosuppression ,adulto ,Middle Aged ,Tissue Donors ,Geographic Locations::Europe::Spain [GEOGRAPHICALS] ,Infectious Diseases ,trasplante de órganos ,virosis::infecciones por virus ARN::infecciones por Retroviridae::infecciones por Deltaretrovirus::infecciones por HTLV-I [ENFERMEDADES] ,Cèl·lules T ,Screening ,Paraparesia espástica tropical ,Raonament basat en casos ,Ubicaciones Geográficas::Europa (Continente)::España [DENOMINACIONES GEOGRÁFICAS] ,Female ,medicine.symptom ,Research Article ,Adult ,medicine.medical_specialty ,Virus Diseases::RNA Virus Infections::Retroviridae Infections::Deltaretrovirus Infections::HTLV-I Infections [DISEASES] ,030106 microbiology ,técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes::estudios retrospectivos [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,T cells ,Asymptomatic ,Health Surveillance of Health Services::Delivery of Health Care::Patient Care::Therapeutics::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Tissue and Organ Harvesting::Organ Transplantation [HEALTH SURVEILLANCE] ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Leucemia de células T adultas ,Internal medicine ,medicine ,VIH (Virus) ,Humans ,Adult T-cell leukaemia ,lcsh:RC109-216 ,Dialysis ,Aged ,Retrospective Studies ,Transplantation ,business.industry ,HIV (Viruses) ,estudios retrospectivos ,donantes de tejidos ,Organ Transplantation ,medicine.disease ,HTLV-I Infections ,Spain ,HTLV-1 ,vigilancia sanitaria de los servicios de salud::prestación sanitaria::asistencia al paciente::terapéutica::técnicas y procedimientos diagnósticos::técnicas de laboratorio clínico::extracción de tejidos y órganos::trasplante de órganos [VIGILANCIA SANITARIA] ,Trasplante ,HTLV-1 Infection ,infecciones por HTLV-I ,business - Abstract
Consortia on behalf of the Spanish HTLV Network: C. Rodríguez, M. Vera, J. del Romero, G. Marcaida, M. D. Ocete, E. Caballero, I. Molina, A. Aguilera, J. J. Rodríguez-Calviño, D. Navarro, C. Rivero, M. D. Vilariño, R. Benito, S. Algarate, J. Gil, R. Ortiz de Lejarazu, S. Rojo, J. M. Eirós, A. San Miguel, C. Manzardo, J. M. Miró, J. García, I. Paz, E. Poveda, E. Calderón, D. Escudero, M. Trigo, J. Diz, M. García-Campello, M. Rodríguez Iglesias, A. Hernández Betancor, A. M. Martín, J. M. Ramos, A. Gimeno, F. Gutiérrez, J. C. Rodríguez, V. Sánchez, C. Gómez Hernando, G. Cilla, E. Pérez Trallero, J. López Aldeguer, L. Fernández Pereira, J. Niubó, M. Hernández, A. M. López Lirola, J. L. Gómez Sirvent, L. Force, C. Cifuentes, S. Pérez, L. Morano, C. Raya, A. González Praetorius, J. L. Pérez, M. Peñaranda, S. Hernáez Crespo, J. M. Montejo, L. Roc, A. Martínez Sapiña, I. Viciana, T. Cabezas, A. Lozano, J. M. Fernández, I. García-Bermejo, G. Gaspar, R. García, M. Górgolas, C. Vegas, J. Blas, P. Miralles, M. Valeiro, T. Aldamiz, N. Margall, C. Guardia, E. do Pico, I. Polo, A. Aguinaga, C. Ezpeleta, S. Sauleda, M. Pirón, R. González, L. Barea, A. Jiménez, L. Blanco, A. Suárez, I. Rodríguez Avial, A. Pérez Rivilla, P. Parra, M. Fernández, M. Fernández Alonso, A. Treviño, S. Requena, L. Benítez Gutiérrez, V. Cuervas Mons, C. de Mendoza, P. Barreiro, V. Soriano, O. Corral & F. Gómez-Gallego, [Background]: HTLV-1 infection is a neglected disease, despite infecting 10–15 million people worldwide and severe illnesses develop in 10% of carriers lifelong. Acknowledging a greater risk for developing HTLV-1 associated illnesses due to immunosuppression, screening is being widely considered in the transplantation setting. Herein, we report the experience with universal HTLV testing of donors and recipients of solid organ transplants in a survey conducted in Spain., [Methods]: All hospitals belonging to the Spanish HTLV network were invited to participate in the study. Briefly, HTLV antibody screening was performed retrospectively in all specimens collected from solid organ donors and recipients attended since the year 2008., [Results]: A total of 5751 individuals were tested for HTLV antibodies at 8 sites. Donors represented 2312 (42.2%), of whom 17 (0.3%) were living kidney donors. The remaining 3439 (59.8%) were recipients. Spaniards represented nearly 80%. Overall, 9 individuals (0.16%) were initially reactive for HTLV antibodies. Six were donors and 3 were recipients. Using confirmatory tests, HTLV-1 could be confirmed in only two donors, one Spaniard and another from Colombia. Both kidneys of the Spaniard were inadvertently transplanted. Subacute myelopathy developed within 1 year in one recipient. The second recipient seroconverted for HTLV-1 but the kidney had to be removed soon due to rejection. Immunosuppression was stopped and 3 years later the patient remains in dialysis but otherwise asymptomatic., [Conclusion]: The rate of HTLV-1 is low but not negligible in donors/recipients of solid organ transplants in Spain. Universal HTLV screening should be recommended in all donor and recipients of solid organ transplantation in Spain. Evidence is overwhelming for very high virus transmission and increased risk along with the rapid development of subacute myelopathy.
- Published
- 2019
162. Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals
- Author
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Roc, Lourdes, de Mendoza, Carmen, Fernandez-Alonso, Miriam, Reina, Gabriel, Soriano, Vicente, Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M. D., Caballero, E., Molina, I, Aguilera, A., Rodriguez-Calvino, J. J., Navarro, D., Rivero, C., Vilarino, M. D., Benito, R., Algarate, S., Gil, J., Ortiz de Lejarazu, R., Rojo, S., Eiros, J. M., San Miguel, A., Manzardo, C., Miro, J. M., Garcia, J., Paz, I, Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Rodriguez-Iglesias, M., Hernandez-Betancor, A., Martin, A. M., Ramos, J. M., Gimeno, A., Gutierrez, F., Rodriguez, J. C., Sanchez, V, Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A. M., Gomez-Sirvent, J. L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J. L., Penaranda, M., Hernaez-Crespo, S., Montejo, J. M., Martinez-Sapina, A., Viciana, I, Cabezas, T., Lozano, A., Fernandez, J. M., Garcia-Bermejo, I, Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I, Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I, Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gutierrez, L., Cuervas-Mons, V, Barreiro, P., Corral, O., Gomez-Gallego, F., and Spanish HTLV Network
- Subjects
0301 basic medicine ,medicine.medical_specialty ,030106 microbiology ,Case Report ,Infectious and parasitic diseases ,RC109-216 ,030230 surgery ,Gastroenterology ,03 medical and health sciences ,Myelopathy ,0302 clinical medicine ,Two kidney ,myelopathy ,Internal medicine ,medicine ,Pharmacology (medical) ,antiretroviral drugs ,Kidney transplantation ,business.industry ,screening ,medicine.disease ,Transplantation ,Infectious Diseases ,Virus type ,HTLV-1 ,business ,transplantation - Abstract
Two kidney transplant recipients from a single donor became infected with HTLV-1 (human T-lymphotropic virus type 1) in Spain. One developed myelopathy 8 months following surgery despite early prescription of antiretroviral therapy. The allograft was removed from the second recipient at month 8 due to rejection and immunosuppressors discontinued. To date, 3 years later, this patient remains infected but asymptomatic. HTLV-1 infection was recognized retrospectively in the donor, a native Spaniard who had sex partners from endemic regions. Our findings call for a reappraisal of screening policies on donor–recipient organ transplantation. Based on the high risk of disease development and the large flux of persons from HTLV-1 endemic regions, pre-transplant HTLV-1 testing should be mandatory in Spain.
- Published
- 2019
163. Hydration and cooking behaviour of three Portuguese Chickpea (Cicer arietinum L.) cultivars
- Author
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Ramos, A. Cristina, Ferreira, Armando, Sousa, Beatriz, Trigo, M. João, Duarte, Isabel, and Esteves, M. Paula
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food and beverages - Abstract
Seeds of three Portuguese kabuli type chickpea cultivars (Elvar, Eldorado and Elixir) were studied for their physicochemical characteristics (biometry, hydration, swelling, texture) and traditional cooking behaviour. A commercial non-identified cultivar from Argentina was used for comparison purposes. Significant differences in seed weight and firmness were observed between the commercial variety and the Portuguese ones. Concerning hydration capacity there are no significant differences between cultivars, however, Eldorado had the lowest hydration and swelling capacities when soaked for 6h at 20ºC. Furthermore, Eldorado seeds tend to soften with cooking more than the other cultivars.
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- 2019
164. Effect of alga Undaria pinnatifida ('wakame') extract on the quality evolution of chilled megrim (Lepidorhombus whiffiagonis)
- Author
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Carmen Campos, Miranda, J. M., Trigo, M., Barros-Velázquez, J., and Aubourg, S. P.
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Microbial activity ,Wakame ,Lipid hydrolysis ,Lepidorhombus whiffiagonis ,Chilling ,Lipid oxidation - Abstract
7 pages, 2 tables, 1 figure, The current study represents an attempt to apply the alga Undaria pinnatifida for the quality enhancement of fish products. For it, ethanolic extracts of this alga were included in the icing system during the chilling storage of megrim (Lepidorhombus whiffiagonis). Lipid damage and microbial activity were analysed in megrim muscle after 0, 2, 6 and 9 days. An inhibitory effect (p < 0.05) on lipid hydrolysis (free fatty acids assessment) development could be observed as a result of the alga presence in the icing medium. In this study, a low formation of primary (i.e., peroxides) and secondary (thiobarbituric acid reactive substances) lipid oxidation compounds was inferred in both control and treated fish samples. However, determination of fluorescent compounds (tertiary lipid oxidation compounds) revealed lower average scores for treated megrim at advanced storage periods (6-9 days), so that a partial inhibition of lipid oxidation development could be concluded as a result of the presence of the alga extract in the icing medium. Compositional analyses revealed a polyphenol content of 11±1 mg gallic acid equivalent g-1 of lyophilised alga and an antioxidant capacity of 27 % (DPPH assay). Interestingly, aerobes, proteolytic and lipolytic bacteria growth was partly slowed down as compared to their control counterparts. Consequently, the proposed novel employment of U. pinnatifida can be considered a promising strategy to enhance seafood quality, This work was supported by the 2013 Cooperation Program “CONICET (Argentine)-CSIC (Spain)” and by the Project PIE 2013-70E001 (CSIC, Spain)
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- 2019
165. Clinical Presentation of Individuals With Human T-Cell Leukemia Virus Type-1 Infection in Spain
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de Mendoza, C, Piron, M, Gonzalez, R, Jimenez, A, Caballero, E, Roc, L, Benito, R, Ramos, JM, Soriano, V, Rodriguez, C, Vera, M, del Romero, J, Marcaida, G, Ocete, MD, Molina, I, Aguilera, A, Rodriguez-Calvino, JJ, Navarro, D, Rivero, C, Vilarino, MD, Algarate, S, Gil, J, de Lejarazu, RO, Rojo, S, Eiros, JM, San Miguel, A, Manzardo, C, Miro, JM, Garcia, J, Paz, I, Poveda, E, Calderon, E, Escudero, D, Trigo, M, Diz, J, Garcia-Campello, M, Rodriguez-Iglesias, M, Hernandez-Betancor, A, Martin, AM, Gimeno, A, Gutierrez, F, Rodriguez, JC, Sanchez, V, Gomez-Hernando, C, Cilla, G, Perez-Trallero, E, Lopez-Aldeguer, J, Fernandez-Pereira, L, Niubo, J, Hernandez, M, Lopez-Lirola, AM, Gomez-Sirvent, JL, Force, L, Cifuentes, C, Perez, S, Morano, L, Raya, C, Gonzalez-Praetorius, A, Perez, JL, Penaranda, M, Hernaez-Crespo, S, Montejo, JM, Martinez-Sapina, A, Viciana, I, Cabezas, T, Lozano, A, Fernandez, JM, Garcia-Bermejo, I, Gaspar, G, Garcia, R, Gorgolas, M, Vegas, C, Blas, J, Miralles, P, Valeiro, M, Aldamiz, T, Margall, N, Guardia, C, do Pico, E, Polo, I, Aguinaga, A, Ezpeleta, C, Sauleda, S, Torres, P, Blanco, L, Suarez, A, Rodriguez-Avial, I, Perez-Rivilla, A, Parra, P, Fernandez, M, Fernandez-Alonso, M, Trevino, A, Requena, S, Benitez-Gutierrez, L, Cuervas-Mons, V, Barreiro, P, Corral, O, and Gomez-Gallego, F
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myelopathy ,adult T-cell leukemia ,HTLV-1 ,screening ,epidemiology - Abstract
Background. Although only 8%-10% of persons infected with human T-cell leukemia virus type 1 (HTLV-1) may develop virus-associated diseases lifelong, misdiagnosis of asymptomatic infected carriers frequently leads to late diagnoses. Methods. A nationwide HTLV-1 register was created in Spain in 1989. A total of 351 infected persons had been reported by the end of 2017. We examined all new HTLV-1 diagnoses during the last decade and compared their clinical presentation. Results. A total of 247 individuals with HTLV-1 infection had been reported in Spain since year 2008. The incidence has remained stable with 20-25 new diagnoses yearly. Women represented 62%. Only 12% were native Spaniards, most of whom were foreigners from Latin America (72.5%). Up to 57 (23%) individuals presented clinically with HTLV-1-associated conditions, including subacute myelopathy (n = 24; 42.1%), T-cell lymphoma (n = 19; 33.3%), or Strongyloides stercoralis infestation (n = 8; 14%). Human T-cell leukemia virus type 1 diagnosis had been made either at blood banks (n = 109; 44%) or at clinics (n = 138; 56%). It is interesting to note that Spaniards and especially Africans were overrepresented among patients presenting with HTLV-1-associated illnesses, suggesting that misdiagnosis and late presentation are more frequent in these populations compared to Latin Americans. Conclusions. Given that 23% of new HTLV-1 diagnoses in Spain are symptomatic, underdiagnosis must be common. Although screening in blood banks mostly identifies asymptomatic Latin American carriers, a disproportionately high number of Spaniards and Africans are unveiled too late, that is, they already suffer from classic HTLV-1 illnesses.
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- 2019
166. HIV co-infection in HTLV-1 carriers in Spain
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de Mendoza, C, Caballero, E, Aguilera, A, Benito, R, Macia, D, Garcia-Costa, J, Soriano, V, Rodriguez, C, Vera, M, del Romero, J, Marcaida, G, Ocete, MD, Molina, I, Rodriguez-Calvino, JJ, Navarro, D, Rivero, C, Vilarino, MD, Algarate, S, Gil, J, de Lejarazu, RO, Rojo, S, Eiros, JM, San Miguel, A, Manzardo, C, Mira, JM, Garcia, J, Paz, I, Poveda, E, Calderon, E, Escudero, D, Trigo, M, Diz, J, Garcia-Campello, M, Rodriguez-Iglesias, M, Hernandez-Betancor, A, Martin, AM, Ramos, JM, Gimeno, A, Gutierrez, F, Rodriguez, JC, Sanchez, V, Gomez-Hernando, C, Cilla, G, Perez-Trallero, E, Lopez-Aldeguer, J, Fernandez-Pereira, L, Niubo, J, Hernandez, M, Lopez-Lirola, AM, Gomez-Sirvent, JL, Force, L, Cifuentes, C, Raya, C, Gonzalez-Praetorius, A, Perez, JL, Penaranda, M, Hernaez-Crespo, S, Montejo, JM, Roc, L, Martinez-Sapina, A, Viciana, I, Cabezas, T, Lozano, A, Fernandez, JM, Garcia-Bermejo, I, Gaspar, G, Garcia, R, Gorgolas, M, Vegas, C, Blas, J, Miralles, P, Valeiro, M, Aldamiz, T, Margall, N, Guardia, C, do Pico, E, Polo, I, Aguinaga, A, Ezpeleta, C, Sauleda, S, Piron, M, Gonzalez, R, Barea, L, Jimenez, A, Blanco, L, Suarez, A, Rodriguez-Avial, I, Perez-Rivilla, A, Parra, P, Fernandez, M, Fernandez-Alonso, M, Reina, G, Trevino, A, Requena, S, Benitez-Gutierrez, L, Cuervas-Mons, V, Barreiro, P, Corral, O, Gomez-Gallego, F, Perez, S, Morano, L, and Spanish HTLV Network
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AIDS ,Epidemiology ,Tropical spastic paraparesis ,Adult T-cell leukemia ,virus diseases ,HIV ,HTLV ,Co-infection ,Antiretroviral therapy ,Late diagnosis - Abstract
Background: Human retroviruses HIV and HTLV share transmission routes. HIV widely spread in Spain during the 80 s through injection drug use and sex, and nowadays HIV rates in Spain account for one of the largest in Europe. In contrast, HTLV-1 is not endemic in Spain, despite hosting huge numbers of migrants from highly endemic regions. Herein, we report the rate and main features of the HIV-HTLV co-infected population in Spain. Methods: A national registry exists in Spain for HTLV since year 1989. Data from standardized case report forms and one centralized lab repository were reviewed, especially for the subset with HTLV-HIV co-infection. Results: Up to December 2018, a total of 369 individuals with HTLV-1 had been diagnosed in Spain. 64% of the population were females, and Latin American individuals accounted for 64.5%. Classical HTLV-associated illnesses were found in 12.7% (myelopathy) and 7.6% (leukemia). HIV coinfection was found in 12 (3.2%). Of those, 3 patients (25%) were female and 39 (75%) were of non Spanish origin. All but two harbored HIV-1 subtype B, being non-B variants found in the two West Africans. Exposure had been sexual in most cases, being 4 homosexual men. Seven HTLV-HIV co-infected patients had developed AIDS and two had developed myelopathy. There was no evidence for increased HTLV-1 clinical pathogenicity due to HIV coinfection. Conclusion: HIV coinfection is infrequent (< 5%) among HTLV-1 carriers in Spain. More than half of co-infected patients come from Latin America. Sexual contact is the most frequent risk behavior, being MSM one third of cases. Late diagnosis explains the high rate (9/12) of clinical manifestations in our HIV-HTLV co-infected population.
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- 2019
167. HTLV testing of solid organ transplant donors
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de Mendoza, C, Roc, L, Fernandez-Alonso, M, Soriano, V, Rodriguez, C, Vera, M, del Romero, J, Marcaida, G, Ocete, MD, Caballero, E, Aguilera, A, Rodriguez-Calvino, JJ, Rivero, C, Vilarino, MD, Benito, R, Algarate, S, de Lejarazu, RO, Rojo, S, Eiros, JM, Ramos, C, Manzardo, C, Miro, JM, Garcia-Costa, J, Calderon, E, Escudero, D, Trigo, M, Diz, J, Garcia-Campello, M, Rodriguez-Iglesias, M, Hernandez-Betancor, A, Martin, AM, Ramos, JM, Gimeno, A, Sanchez, V, Guzman, M, Gomez-Hernando, C, Echeverria, MJ, Cilla, G, Fernandez-Pereira, L, Hernandez, M, Lopez-Lirola, AM, Gomez-Sirvent, JL, Force, L, Cifuentes, C, Perez, S, Morano, L, Raya, C, Gonzalez-Praetorius, A, Penaranda, M, Nieto, MC, Montejo, JM, Viciana, I, Cabezas, T, Lozano, A, Perez-Camacho, I, Fernandez, JM, Garcia-Bermejo, I, Gaspar, G, Tellez, R, Gorgolas, M, Perez, L, Monsalvo, S, Valeiro, M, Aldamiz, T, Margall, N, Guardia, C, do Pico, E, Sauleda, S, Piron, M, Gonzalez, R, Richart, A, Barea, L, Jimenez, A, Blanco, L, Suarez, A, Rodriguez-Avial, I, Parra, P, Fernandez, M, Reina, G, Trevino, A, Requena, S, Benitez-Gutierrez, L, Cuervas-Mons, V, Barreiro, P, Corral, O, and Gomez-Gallego, F
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- 2019
168. Treatment outcome in dually HIV-1 and HIV-2 coinfected patients living in Spain
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Requena S, Caballero E, Lozano A, Rios-Villegas M, Benito R, Rojo S, Cabezas T, Macia M, Nieto M, Soriano V, de Mendoza C, Rodriguez C, Vera M, del Romero J, Ocete M, Aguilera A, Amengual M, Cervantes M, Algarate S, de Lejarazu R, Eiros J, Ramos C, Garcia-Costa J, Calderon E, Trigo M, Diz J, Garcia-Campello M, Rodriguez-Iglesias M, Hernandez-Betancor A, Ramos J, Gimeno A, Sanchez V, Gomez-Hernando C, Echeverria M, Cilla G, Perez-Trallero E, Fernandez-Pereira L, Niubo J, Margall N, Hernandez M, Lopez-Lirola A, Gomez-Sirvent J, Force L, Sauca M, Perez S, Morano L, Raya C, Praetorius A, Cifuentes C, Penaranda M, Montejo J, Roc L, Martinez-Sapina A, Viciana I, Perez-Camacho I, Fernandez-Fuertes E, Fernandez J, Bermejo I, Gaspar G, Gorgolas M, Vegas C, Blas J, Tellez R, Perez L, Valeiro M, Aldamiz T, Garcia F, Suarez A, Rodriguez-Avial I, Barreiro P, Gomez-Gallego F, Corral O, Benitez-Gutierrez L, and Cuervas-Mons V
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HIV-2 ,HIV-1 ,virus diseases ,antiretrovirals - Abstract
Background: Whereas HIV-1 has spread globally, HIV-2 is mainly found in West Africa where dual HIV-1/HIV-2 coinfection is nowadays uncommon. Herein, we report the rate, main characteristics, and treatment outcomes of all dually infected patients living in Spain. Methods: We identified retrospectively all persons coinfected with HIV-1 recorded at the Spanish HIV-2 registry. Dual infection had been confirmed using PCR in plasma and/or cells, and/or using discriminatory serological tests. Results: From a total of 373 individuals with HIV-2 recorded at the Spanish registry, 34 (9.1%) were coinfected with HIV-1. Compared with HIV-2 monoinfected persons, dually infected patients were more often male (67.6%), presented with lower median CD4(+) cell counts (204 cells/mu l), and had developed more frequently AIDS events (26.5%). Although 61.7% came from West Africa, 6 (17.6%) were native Spaniards. HIV-1 non-B subtypes were recognized in 75% of coinfected patients, being the most prevalent CRF02_AG. At baseline, 45% of dually infected patients had undetectable plasma HIV-2 RNA. After a median follow-up of 32 (13-48) months on antiretroviral therapy, dually infected patients achieved undetectable viremia in 85% for HIV-1, in 80% for HIV-2; and in 70% for both viruses. Median CD4(+) cell counts reached up to 418 cells/mu l. Conclusion: Roughly 9% of individuals with HIV-2 infection living in Spain are coinfected with HIV-1. Overall, 70% of dually infected patients achieved viral suppression for both viruses under antiretroviral therapy. Given the relatively large population of West Africans living in Spain and the continuous migration flow from HIV-2 endemic areas, HIV-1/HIV-2 coinfection should always be excluded at first diagnosis in all HIV-seroreactive persons. Copyright (C) 2019 Wolters Kluwer Health, Inc. All rights reserved.
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- 2019
169. Clinical experience with integrase inhibitors in HIV-2-infected individuals in Spain
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Requena, S, Lozano, A B, Caballero, E, García, F, Nieto, M C, Téllez, R, Fernández, J M, Trigo, M, Rodríguez-Avial, I, Martín-Carbonero, L, Miralles, P, Soriano, V, de Mendoza, C, and HIV-2 Spanish Study Group
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0301 basic medicine ,Microbiology (medical) ,Adult ,Male ,medicine.medical_specialty ,Adolescent ,030106 microbiology ,Integrase inhibitor ,Viremia ,HIV Infections ,Drug resistance ,Microbial Sensitivity Tests ,Virus ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Drug Resistance, Viral ,medicine ,Humans ,Pharmacology (medical) ,030212 general & internal medicine ,HIV Integrase Inhibitors ,Treatment Failure ,Retrospective Studies ,Pharmacology ,biology ,business.industry ,virus diseases ,Retrospective cohort study ,Middle Aged ,medicine.disease ,3. Good health ,Integrase ,CD4 Lymphocyte Count ,Infectious Diseases ,Spain ,Cohort ,HIV-2 ,Mutation ,biology.protein ,RNA, Viral ,Observational study ,Female ,business - Abstract
Background HIV-2 is a neglected virus despite estimates of 1-2 million people being infected worldwide. The virus is naturally resistant to some antiretrovirals used to treat HIV-1 and therapeutic options are limited for patients with HIV-2. Methods In this retrospective observational study, we analysed all HIV-2-infected individuals treated with integrase strand transfer inhibitors (INSTIs) recorded in the Spanish HIV-2 cohort. Demographics, treatment modalities, laboratory values, quantitative HIV-2 RNA and CD4 counts as well as drug resistance were analysed. Results From a total of 354 HIV-2-infected patients recruited by the Spanish HIV-2 cohort as of December 2017, INSTIs had been given to 44, in 18 as first-line therapy and in 26 after failing other antiretroviral regimens. After a median follow-up of 13 months of INSTI-based therapy, undetectable viraemia for HIV-2 was achieved in 89% of treatment-naive and in 65.4% of treatment-experienced patients. In parallel, CD4 gains were 82 and 126 cells/mm3, respectively. Treatment failure occurred in 15 patients, 2 being treatment-naive and 13 treatment-experienced. INSTI resistance changes were recognized in 12 patients: N155H (5), Q148H/R (3), Y143C/G (3) and R263K (1). Conclusions Combinations based on INSTIs are effective and safe treatment options for HIV-2-infected individuals. However, resistance mutations to INSTIs are selected frequently in failing patients, reducing the already limited treatment options.
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- 2019
170. Clinical experience with integrase inhibitors in HIV-2-infected individuals in Spain
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Garcia F, Martin-Carbonero L, Rodriguez C, Vera M, del Romero J, Marcaida G, Ocete M, Caballero E, Aguilera A, Benito R, de Lejarazu R, Rojo S, Eiros J, Ramos C, Garcia J, Paz I, Trigo M, Diz J, Garcia-Campello M, Rodriguez-Iglesias M, Hernandez-Betancor A, Martin A, Ramos J, Gimeno A, Sanchez V, Gomez-Hernando C, Cilla G, Perez-Trallero E, Fernandez-Pereira L, Niubo J, Hernandez M, Lopez-Lirola A, Gomez-Sirvent J, Force L, Cabrera J, Perez S, Morano L, Raya C, Gonzalez-Praetorius A, Cifuentes C, Penaranda M, Nieto M, Montejo J, Roc L, Viciana I, Lozano A, Fernandez-Fuertes E, Fernandez J, Garcia-Bermejo I, Gaspar G, Tellez R, Gorgolas M, Diaz J, Miralles P, Perez L, Valeiro M, Aldamiz T, Margall N, Suarez A, Rodriguez-Avial I, Requena S, Benitez-Gutierrez L, Cuervas-Mons V, de Mendoza C, Barreiro P, and Soriano V
- Abstract
Background: HIV-2 is a neglected virus despite estimates of 1-2 million people being infected worldwide. The virus is naturally resistant to some antiretrovirals used to treat HIV-1 and therapeutic options are limited for patients with HIV-2. Methods: In this retrospective observational study, we analysed all HIV-2-infected individuals treated with integrase strand transfer inhibitors (INSTIs) recorded in the Spanish HIV-2 cohort. Demographics, treatment modalities, laboratory values, quantitative HIV-2 RNA and CD4 counts as well as drug resistance were analysed. Results: From a total of 354 HIV-2-infected patients recruited by the Spanish HIV-2 cohort as of December 2017, INSTIs had been given to 44, in 18 as first-line therapy and in 26 after failing other antiretroviral regimens. After a median follow-up of 13 months of INSTI-based therapy, undetectable viraemia for HIV-2 was achieved in 89% of treatment-naive and in 65.4% of treatment-experienced patients. In parallel, CD4 gains were 82 and 126 cells/mm(3), respectively. Treatment failure occurred in 15 patients, 2 being treatment-naive and 13 treatment-experienced. INSTI resistance changes were recognized in 12 patients: N155H (5), Q148H/R (3), Y143C/G (3) and R263K (1). Conclusions: Combinations based on INSTIs are effective and safe treatment options for HIV-2-infected individuals. However, resistance mutations to INSTIs are selected frequently in failing patients, reducing the already limited treatment options.
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- 2019
171. Detection of airborne allergen (Ole e 1) in relation to Olea europaea pollen in S Spain
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De Linares, C., Nieto-Lugilde, D., Alba, F., de la Guardia, C. Díaz, Galán, C., and Trigo, M. M.
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- 2007
172. Comportamento de três cultivares portuguesas de grão-de-bico (Cicer arietinum L.) durante os processos de hidratação e cocção
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Ramos,A. Cristina, Ferreira,Armando, Sousa,Beatriz, Trigo,M. João, Duarte,Isabel, and Esteves,M. Paula
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swelling ,firmeza ,cooking ,intumescimento ,chickpea ,grão-de-bico ,food and beverages ,hidratação ,cozimento ,firmness ,hydration - Abstract
Seeds of three Portuguese kabuli type chickpea cultivars (Elvar, Eldorado and Elixir) were studied for their physicochemical characteristics (biometry, hydration, swelling, texture) and traditional cooking behaviour. A commercial non-identified cultivar from Argentina was used for comparison purposes. Significant differences in seed weight and firmness were observed between the commercial variety and the Portuguese ones. Concerning hydration capacity there are no significant differences between cultivars, however, Eldorado had the lowest hydration and swelling capacities when soaked for 6h at 20ºC. Furthermore, Eldorado seeds tend to soften with cooking more than the other cultivars., Revista de Ciências Agrárias, vol. 41 n.º 4 (2018)
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- 2018
173. Chandra high-resolution spectra of 4U 1630-47: the disappearance of the wind
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Gatuzz, E., Trigo, M., Miller-Jones, James, Migliari, S., Gatuzz, E., Trigo, M., Miller-Jones, James, and Migliari, S.
- Abstract
We present the analysis of six Chandra X-ray high-resolution observations of the black hole low-mass X-ray binary 4U 1630-47 taken during its 2012–2013 outburst. Fe XXVI K α, K β, Fe XXV K α, K β, and Ca XX K α blueshifted absorption lines were identified in the first four observations, which correspond to soft accretion states. The remaining observations, associated to intermediate and possibly hard accretion states, do not show significant absorption features down to equivalent width of 1 eV for both Fe XXVI and Fe XXV. We inferred wind launching radii between 1.2 − 2.0 (1012 cm/n) × 1011 cm and column densities N(H) > 1023 cm−2. In the first four observations, we found that thermal pressure is likely to be the dominant launching mechanism for the wind, although such conclusions depend on the assumed density. We used the spectral energy distributions obtained from our continuum modelling to compute thermal stability curves for all observations using the XSTAR photoionization code. We found that the absence of lines in the transitional state cannot be attributed to an evolution of the plasma caused by thermal instabilities derived from the change in the continuum spectrum. In contrast, the disappearance of the wind could indicate an acceleration of the flow or that the plasma has been exhausted during the soft state.
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- 2019
174. Coronary Microcirculation Downstream Non-Infarct-Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology-Guided Revascularization
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Mejia-Renteria, H., Lee, J.M., Hoeven, N.W. Van Der, Gonzalo, N., Jimenez-Quevedo, P., Nombela-Franco, L., Nunez-Gil, I.J., Salinas, P., Trigo, M. Díaz, Cerrato, E., Royen, N. van, Knaapen, P., Koo, B.K., Macaya, C., Fernandez-Ortiz, A., Escaned, J., Mejia-Renteria, H., Lee, J.M., Hoeven, N.W. Van Der, Gonzalo, N., Jimenez-Quevedo, P., Nombela-Franco, L., Nunez-Gil, I.J., Salinas, P., Trigo, M. Díaz, Cerrato, E., Royen, N. van, Knaapen, P., Koo, B.K., Macaya, C., Fernandez-Ortiz, A., and Escaned, J.
- Abstract
Contains fulltext : 209416.pdf (publisher's version ) (Open Access), Background Concerns exist about reliability of pressure-wire-guided coronary revascularization of non-infarct-related arteries (non- IRA ). We investigated whether physiological assessment of non- IRA during the subacute phase of myocardial infarction might be flawed by microcirculatory dysfunction. Methods and Results We analyzed non- IRA that underwent fractional flow reserve, coronary flow reserve, and the index of microcirculatory resistance assessment. Microcirculation and hyperemic response were evaluated in 49 acute myocardial infarction patients (59 non- IRA ) and compared with a matched control group of 46 stable angina ( SA ) patients (59 vessels). Time between acute myocardial infarction to physiological interrogation was 5.9+/-2.4 days. Fractional flow reserve was similar in both groups (0.79+/-0.11 in non- IRA versus 0.80+/-0.13 in SA vessels, P=0.527). Lower coronary flow reserve values were found in non- IRA compared with SA vessels (1.77 [1.25-2.76] versus 2.44 [1.63-4.00], P=0.018), primarily driven by an increased baseline flow in non- IRA (rest mean transit time 0.58 [0.32-0.83] versus 0.65 s [0.39-1.20], P=0.045), whereas the hyperemic flow was similar (hyperemic mean transit time 0.26 [0.20-0.42] versus 0.26 s [0.18-0.35], P=0.873). No differences were found regarding index of microcirculatory resistance (15.6 [10.4-21.8] in non- IRA versus 16.7 [11.6-23.6] U in SA vessels, P=0.559). During adenosine infusion, the hyperemic response was similar in both groups (non- IRA versus SA vessels) in terms of the resistive reserve ratio (3.1+/-2.1 versus 3.7+/-2.2, P=0.118). Conclusions In the subacute phase of myocardial infarction, non- IRA show an increased baseline flow that may cause abnormal coronary flow reserve despite preserved hyperemic flow. In non- IRA , microcirculatory resistance and adenosine-induced hyperemic response are similar to those found in SA patients. From a physiological perspective, these findings support the use of fractional f
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- 2019
175. Femtosecond x-ray diffraction reveals a liquid–liquid phase transition in phase-change materials
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German Research Foundation, European Commission, RWTH Aachen University, Department of Energy (US), Swedish Research Council, Ministerio de Ciencia, Innovación y Universidades (España), Zalden, P., Quirin, F., Schumacher, M., Siegel, Jan, Wei, S., Koc, A., Nicoul, M., Trigo, M., Andreasson, P., Enquist, H., Shu, M.J., Pardini, T., Chollet, M., Zhu, D., Lemke, H., Ronneberger, I., Larsson, J., Lindenberg, A.M., Fischer, H. E., Hau-Riege, S., Reis, D.A., Mazzarello, R., Wuttig, Matthias, Sokolowski-Tinten, K., German Research Foundation, European Commission, RWTH Aachen University, Department of Energy (US), Swedish Research Council, Ministerio de Ciencia, Innovación y Universidades (España), Zalden, P., Quirin, F., Schumacher, M., Siegel, Jan, Wei, S., Koc, A., Nicoul, M., Trigo, M., Andreasson, P., Enquist, H., Shu, M.J., Pardini, T., Chollet, M., Zhu, D., Lemke, H., Ronneberger, I., Larsson, J., Lindenberg, A.M., Fischer, H. E., Hau-Riege, S., Reis, D.A., Mazzarello, R., Wuttig, Matthias, and Sokolowski-Tinten, K.
- Abstract
In phase-change memory devices, a material is cycled between glassy and crystalline states. The highly temperature-dependent kinetics of its crystallization process enables application in memory technology, but the transition has not been resolved on an atomic scale. Using femtosecond x-ray diffraction and ab initio computer simulations, we determined the time-dependent pair-correlation function of phase-change materials throughout the melt-quenching and crystallization process. We found a liquid–liquid phase transition in the phase-change materials AgInSbTe and GeSb at 660 and 610 kelvin, respectively. The transition is predominantly caused by the onset of Peierls distortions, the amplitude of which correlates with an increase of the apparent activation energy of diffusivity. This reveals a relationship between atomic structure and kinetics, enabling a systematic optimization of the memory-switching kinetics.
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- 2019
176. evolving radio jet from the neutron star X-ray binary 4U 1820−30.
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Russell, T D, Degenaar, N, den Eijnden, J van, Del Santo, M, Segreto, A, Altamirano, D, Beri, A, Díaz Trigo, M, and Miller-Jones, J C A
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X-ray binaries ,NEUTRON stars ,SYNCHROTRON radiation ,STELLAR oscillations ,ACCRETION disks ,RADIO jets (Astrophysics) ,SOFT X rays - Abstract
The persistently bright ultracompact neutron star low-mass X-ray binary 4U 1820−30 displays an ∼170 d accretion cycle, evolving between phases of high and low X-ray modes, where the 3–10 keV X-ray flux changes by a factor of up to ≈8. The source is generally in a soft X-ray spectral state, but may transition to a harder state in the low X-ray mode. Here, we present new and archival radio observations of 4U 1820−30 during its high and low X-ray modes. For radio observations taken within a low mode, we observed a flat radio spectrum consistent with 4U 1820−30 launching a compact radio jet. However, during the high X-ray modes the compact jet was quenched and the radio spectrum was steep, consistent with optically thin synchrotron emission. The jet emission appeared to transition at an X-ray luminosity of |$L_{\rm X (3-10\, keV)} \sim 3.5 \times 10^{37} (D/\rm {7.6\, kpc})^{2}$| erg s
−1 . We also find that the low-state radio spectrum appeared consistent regardless of X-ray hardness, implying a connection between jet quenching and mass accretion rate in 4U 1820−30, possibly related to the properties of the inner accretion disc or boundary layer. [ABSTRACT FROM AUTHOR]- Published
- 2021
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- View/download PDF
177. Ultrafast laser-induced melting and ablation studied by time-resolved diffuse X-ray scattering
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Meyer zu Heringdorf F., Payer T., Meyer S., Becker T., Larsson J., Gaffney K.J., Fuchs M., Trigo M., Ghimire S., Chen J., Reis D.A., Lemke H., Chollet M., Zhu D., Barty A., Fritz D.M., Lindenberg A.M., Quirin F., Nicoul M., Horn von Hoegen M., Jerman M., and Sokolowski-Tinten K.
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Physics ,QC1-999 - Abstract
Time-resolved diffuse X-ray scattering with 50 fs, 9.5 keV X-ray pulses from the Linear Coherent Light Source was used to study the structural dynamics in materials undergoing rapid melting and ablation after fs laser excitation.
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- 2013
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178. Measuring 3D magnetic correlations during the photo-induced melting of electronic order in La0.5Sr1.5MnO4
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Wilkins S. B., Cavalieri A.L., Moore R., Chuang Y. D., Lee W. S., Krupin O., Trigo M., Schlotter W., Turner J.J., Khanna V., Bromberger H., Först M., Wall S., Tobey R.I., Zeng H., Mitchell J. F., Dhesi S.S., Cavalleri A., and Hill J. P.
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Physics ,QC1-999 - Abstract
Time-resolved x-ray diffraction measures the dynamics of antiferromagnetic correlations by reconstructing the reciprocal-space scattering volume for the magnetic Bragg peak. Modifications in the scattering line shape along the three principal reciprocal lattice directions are measured.
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- 2013
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179. The 4-(4′-nitrophenylsulphonyl)phenyl group for carboxyl activation in peptide synthesis
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Amaral-Trigo, M. J. S. A., primary, Santos, M. I. A. Oliveira, additional, and Franco, M. M. T. B. A., additional
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- 1995
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180. Use of Ionophores in Goat Feeding
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G. Muro, M., Arias, R., S. Trigo, M., A. Eirin, M., C. Cattáneo, A., Steffen, K., and A. Cordiviola, C.
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Goats ,Intake ,Monensin - Abstract
The objective of this study was to evaluate the effect of monensin addition on the total dry matter intake, in goat diets, composed of 30 % alfalfa hay and 70 % corn. Four fistulated cross breed goats (Nubian x Creole), 39.77 ± 1.07 kg live body weight (BW), were used in experimental design. Two experiments were carried out: I) Determining total dry matter intake (TDMI), pasture dry matter intake (PDMI), total daily and hourly intake (TDHI) and total dry matter digestibility (TDMD); II) Determining ruminal pH. Treatments consisted of an instance without monensin (D0), and another one with monensin (D1). In both cases, intake level was adjusted to 3 % of BW. There were no significant effects (p < 0.05) on TDMI, PDMI, TDHI, TDMD and BW. The registered TDHI during the 12 h after feed had an effect on time. The area below the curve, with a 5.8 and 6 pH threshold, proved a significant linear drop-off (p < 0.05) for D1. As regards the hours with pH value below pH threshold, there were no significant differences (p > 0.05) between treatments, only a tendency (p = 0,074) to keep pH values below 5.8 for a greater number hours in D0. The average pH of the day showed a tendency to be higher (p = 0,056) for D1. The lowest ruminal pH was observed between the 8 and 12 h after food intake, and with significant differences (p > 0.05) between hours, but the treatment had no effects on the evolution of pH in time. Therefore, we can conclude that the addition of monensin in highly energetic diets for goats had a moderating effect in the ruminal pH, and in the number of daily food concentrate meals. However, there was no register of acute acidosis with these diets.Read Complete Article at ijSciences: V72018061706 AND DOI: http://dx.doi.org/10.18483/ijSci.1706
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- 2018
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181. A bright mid-infrared excess in MAXI J1820+070
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Russell, D.M., Baglio, M.C., Bright, J., Fender, R., Al Qaissieh, T., Palado, A., Gabuya, A., Asmus, D., Belloni, T., Bel, M.C., Casella, P., Ceccobello, C., Corbel, S., Diaz Trigo, M., Gallo, E., Gandhi, P., Homan, J., Koljonen, K., Lewis, F., Markoff, S., Miller-Jones, J.C.A., O'Brien, K., Russell, T.D., Saikia, P., Sivakoff, G., Shahbaz, T., Soria, R., Tetarenko, A., van den Ancker, M., and High Energy Astrophys. & Astropart. Phys (API, FNWI)
- Abstract
MAXI J1820+070 (ASASSN-18ey) is a black hole candidate X-ray binary (e.g. ATel #11399, #11418, #11420). It is currently in a bright, hard spectral state (ATel #11423, #11427, #11439).
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- 2018
182. QuantiFERON-TB Gold In-Tube as a Confirmatory Test for Tuberculin Skin Test in Tuberculosis Contact Tracing: A Noninferiority Clinical Trial
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Muñoz L, Santin M, Alcaide F, Ruíz-Serrano MJ, Gijón P, Bermúdez E, Domínguez-Castellano A, Navarro MD, Ramírez E, Pérez-Escolano E, López-Prieto MD, Gutiérrez-Rodriguez J, Anibarro L, Calviño L, Trigo M, Cifuentes C, García-Gasalla M, Payeras A, Gasch O, Espasa M, Agüero R, Ferrer D, Casas X, Gonzalez-Cuevas MA, García-Zamalloa A, Bikuña E, Lecuona M, Galindo R, Ramírez-Lapausa M, and Carrillo R
- Subjects
latent tuberculosis infection ,preventive therapy ,interferon-gamma release assays ,tuberculin skin test - Abstract
BACKGROUND: Screening strategies based on interferon-? release assays in tuberculosis contact tracing may reduce the need for preventive therapy without increasing subsequent active disease. METHODS: We conducted an open-label, randomized trial to test the noninferiority of a 2-step strategy with the tuberculin skin test (TST) followed by QuantiFERON-TB Gold In-Tube (QFT-GIT) as a confirmatory test (the TST/QFT arm) to the standard TST-alone strategy (TST arm) for targeting preventive therapy in household contacts of patients with tuberculosis. Participants were followed for 24 months after randomization. The primary endpoint was the development of tuberculosis, with a noninferiority margin of 1.5 percentage points. RESULTS: A total of 871 contacts were randomized. Four contacts in the TST arm and 2 in the TST/QFT arm developed tuberculosis. In the modified intention-to-treat analysis, this accounted for 0.99% in the TST arm and 0.51% in the TST/QFT arm (-0.48% difference; 97.5% confidence interval [CI], -1.86% to 0.90%); in the per-protocol analysis, the corresponding rates were 1.67% and 0.82% in the TST and TST/QFT arms, respectively (-0.85% difference; 97.5% CI, -3.14% to 1.43%). Of the 792 contacts analyzed, 65.3% in the TST arm and 42.2% in the TST/QFT arm were diagnosed with tuberculosis infection (23.1% difference; 95% CI, 16.4% to 30.0%). CONCLUSIONS: In low-incidence settings, screening household contacts with the TST and using QFT-GIT as a confirmatory test is not inferior to TST-alone for preventing active tuberculosis, allowing a safe reduction of preventive treatments. CLINICAL TRIALS REGISTRATION: NCT01223534.
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- 2018
183. Predicting Disengagement from Judicial Proceedings by Female Victims of Intimate Partner Violence in Spain: A Systematic Replication With Prospective Data
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García-Jiménez, María, primary, Cala-Carrillo, María Jesús, additional, and Trigo, M. Eva, additional
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- 2019
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184. P5613Proportional relationship between early mobilization of bone marrow progenitor cells and the extent of vascular injury during coronary stenting: insights on the role of systemic mechanisms of vascular
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Jimenez-Quevedo, P, primary, Bernardo, E, additional, Del Trigo, M, additional, Otsuki, S, additional, Nombela Franco, L, additional, Brugaletta, S, additional, Ortega Pozi, A, additional, Salinas, P, additional, Nunez Gil, I, additional, Megia Renteria, H, additional, Fernandez Ortiz, A, additional, Macaya, C, additional, Escaned, J, additional, Sabate, M, additional, and Gonzalo, N, additional
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- 2019
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185. Near-ground effect of height on pollen exposure
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Rojo, Jesús, primary, Oteros, Jose, additional, Pérez-Badia, Rosa, additional, Cervigón, Patricia, additional, Ferencova, Zuzana, additional, Gutiérrez-Bustillo, A. Monserrat, additional, Bergmann, Karl-Christian, additional, Oliver, Gilles, additional, Thibaudon, Michel, additional, Albertini, Roberto, additional, Rodríguez-De la Cruz, David, additional, Sánchez-Reyes, Estefanía, additional, Sánchez-Sánchez, José, additional, Pessi, Anna-Mari, additional, Reiniharju, Jukka, additional, Saarto, Annika, additional, Calderón, M. Carmen, additional, Guerrero, César, additional, Berra, Daniele, additional, Bonini, Maira, additional, Chiodini, Elena, additional, Fernández-González, Delia, additional, García, José, additional, Trigo, M. Mar, additional, Myszkowska, Dorota, additional, Fernández-Rodríguez, Santiago, additional, Tormo-Molina, Rafael, additional, Damialis, Athanasios, additional, Kolek, Franziska, additional, Traidl-Hoffmann, Claudia, additional, Severova, Elena, additional, Caeiro, Elsa, additional, Ribeiro, Helena, additional, Magyar, Donát, additional, Makra, László, additional, Udvardy, Orsolya, additional, Alcázar, Purificación, additional, Galán, Carmen, additional, Borycka, Katarzyna, additional, Kasprzyk, Idalia, additional, Newbigin, Ed, additional, Adams-Groom, Beverley, additional, Apangu, Godfrey P., additional, Frisk, Carl A., additional, Skjøth, Carsten A., additional, Radišić, Predrag, additional, Šikoparija, Branko, additional, Celenk, Sevcan, additional, Schmidt-Weber, Carsten B., additional, and Buters, Jeroen, additional
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- 2019
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186. Discovery of millihertz quasi-periodic oscillations in the X-ray binary EXO 0748−676
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Mancuso, G C, primary, Altamirano, D, additional, García, F, additional, Lyu, M, additional, Méndez, M, additional, Combi, J A, additional, Díaz-Trigo, M, additional, and in’t Zand, J J M, additional
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- 2019
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187. Coherent order parameter dynamics in SmTe3
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Trigo, M., primary, Giraldo-Gallo, P., additional, Kozina, M. E., additional, Henighan, T., additional, Jiang, M. P., additional, Liu, H., additional, Clark, J. N., additional, Chollet, M., additional, Glownia, J. M., additional, Zhu, D., additional, Katayama, T., additional, Leuenberger, D., additional, Kirchmann, P. S., additional, Fisher, I. R., additional, Shen, Z. X., additional, and Reis, D. A., additional
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- 2019
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188. The Effect of Wheat Bran on the Total Apparent Digestibility of Dry Matter, NDF, ADF and CP in Goat Diets
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Arias, R., primary, G. Muro, M., additional, S. Trigo, M., additional, Eirin, M., additional, Boyezuk, D., additional, and A. Cordiviola, C., additional
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- 2019
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189. Activated 4-(4’,-nitrophenylthio)phenyl esters in peptide synthesis
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Trigo, M. J. S. A. Amaral, primary, Santos, M. I. A. Oliveira, additional, Franco, M. M. T. B. A., additional, Teixeira, M. P. S. V. R., additional, and van Zanden, M. N. A., additional
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- 1993
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190. Modelling the disc atmosphere of the low mass X-ray binary EXO 0748-676
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Psaradaki, I., primary, Costantini, E., additional, Mehdipour, M., additional, and Díaz Trigo, M., additional
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- 2018
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191. The 2-(4-nitrophenylsulphonyl)ethyl ester of L-cysteine in the synthesis of peptides
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Amaral Trigo, M. J. S. A., primary and Gomes, M. J. R., additional
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- 1991
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192. RAST-INHIBITION AND RHINOMANOMETRY IN RICINUS COMMUNIS POLLEN SENSITIZED PATIENTS : 154
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Garcia, J. J., Bartolomé, B., Carmona, M. J., Barceló, J. M., Fernández, S., Negro, M. A., Trigo, M. M., Torrecillas, M., Miranda, A., and Vega, J. M.
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- 1997
193. Pollinosis due to Australian pine (Casuarina): an aerobiologic and clinical study in southern Spain
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García, J. J., Trigo, M. M., Cabezudo, B., Recio, M., Vega, J. M., Barber, D., Carmona, M. J., Cervera, J. A., Toro, F. J., and Miranda, A.
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- 1997
194. RICINUS COMMUNIS POLLEN SENSITIZATION : P 378
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García, J. J., Bartolomé, B., Trigo, M. M., Cabezudo, B., Muñoz, M. A., Barceló, J. M., Fernández, S., and Cervera, J. A.
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- 1996
195. Ultrafast terahertz field control of electronic and structural interactions in vanadium dioxide
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Gray, A. X., Hoffmann, M. C., Jeong, J., Aetukuri, N. P., Zhu, D., Hwang, H. Y., Brandt, N. C., Wen, H., Sternbach, A. J., Bonetti, S., Reid, A. H., Kukreja, R., Graves, C., Wang, T., Granitzka, P., Chen, Z., Higley, D. J., Chase, T., Jal, E., Abreu, E., Liu, M. K., Weng, T-C, Sokaras, D., Nordlund, D., Chollet, M., Alonso-Mori, R., Lemke, H., Glownia, J. M., Trigo, M., Zhu, Y., Ohldag, H., Freeland, J. W., Samant, M. G., Berakdar, J., Averitt, R. D., Nelson, K. A., Parkin, S. S. P., Dürr, Hermann, Gray, A. X., Hoffmann, M. C., Jeong, J., Aetukuri, N. P., Zhu, D., Hwang, H. Y., Brandt, N. C., Wen, H., Sternbach, A. J., Bonetti, S., Reid, A. H., Kukreja, R., Graves, C., Wang, T., Granitzka, P., Chen, Z., Higley, D. J., Chase, T., Jal, E., Abreu, E., Liu, M. K., Weng, T-C, Sokaras, D., Nordlund, D., Chollet, M., Alonso-Mori, R., Lemke, H., Glownia, J. M., Trigo, M., Zhu, Y., Ohldag, H., Freeland, J. W., Samant, M. G., Berakdar, J., Averitt, R. D., Nelson, K. A., Parkin, S. S. P., and Dürr, Hermann
- Abstract
Vanadium dioxide (VO2), an archetypal correlated-electron material, undergoes an insulator-metal transition near room temperature that exhibits electron-correlation-driven and structurally driven physics. Using ultrafast temperature- and fluence-dependent optical spectroscopy and x-ray scattering, we show that multiple interrelated electronic and structural processes in the nonequilibrium dynamics in VO2 can be disentangled in the time domain. Specifically, following intense subpicosecond terahertz (THz) electric-field excitation, a partial collapse of the insulating gap occurs within the first picosecond. At temperatures sufficiently close to the transition temperature and for THz peak fields above a threshold of approximately 1 MV/cm, this electronic reconfiguration initiates a change in lattice symmetry taking place on a slower timescale. We identify the kinetic energy increase of electrons tunneling in the strong electric field as the driving force, illustrating a promising method to control electronic and structural interactions in correlated materials on an ultrafast timescale.
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- 2018
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196. Influence of Microcirculatory Dysfunction on Angiography-Based Functional Assessment of Coronary Stenoses
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Mejia-Renteria, H., Lee, J.M., Lauri, F., Hoeven, N.W. Van Der, Waard, G.A. de, Macaya, F., Perez-Vizcayno, M.J., Gonzalo, N., Jimenez-Quevedo, P., Nombela-Franco, L., Salinas, P., Nunez-Gil, I., Trigo, M. Díaz, Goto, S., Lee, H.J., Liontou, C., Fernandez-Ortiz, A., Macaya, C., Royen, N. van, Koo, B.K., Escaned, J., Mejia-Renteria, H., Lee, J.M., Lauri, F., Hoeven, N.W. Van Der, Waard, G.A. de, Macaya, F., Perez-Vizcayno, M.J., Gonzalo, N., Jimenez-Quevedo, P., Nombela-Franco, L., Salinas, P., Nunez-Gil, I., Trigo, M. Díaz, Goto, S., Lee, H.J., Liontou, C., Fernandez-Ortiz, A., Macaya, C., Royen, N. van, Koo, B.K., and Escaned, J.
- Abstract
Item does not contain fulltext, OBJECTIVES: The authors sought to evaluate the influence of coronary microcirculatory dysfunction (CMD) on the diagnostic performance of the quantitative flow ratio (QFR). BACKGROUND: Functional angiographic assessment of coronary stenoses based on fluid dynamics, such as QFR, constitutes an attractive alternative to fractional flow reserve (FFR). However, it is unknown whether CMD affects the reliability of angiography-based functional indices. METHODS: FFR and the index of microcirculatory resistance (IMR) were measured in 300 vessels (248 patients) as part of a multicenter international registry. QFR was calculated at a blinded core laboratory. Vessels were classified into 2 groups according to microcirculatory status: low IMR (<23 U), and high IMR (>/=23 U, CMD). The impact of CMD on the diagnostic performance of QFR, as well as on incremental value of QFR over quantitative angiography, was assessed using FFR as reference. RESULTS: Percent diameter stenosis (%DS) and FFR were similar in low- and high-IMR groups (%DS 51 +/- 12% vs. 53 +/- 11%; p = 0.16; FFR 0.80 +/- 0.11 vs. 0.81 +/- 0.11; p = 0.23, respectively). In the overall cohort, classification agreement (CA) between QFR and FFR and diagnostic efficiency of QFR (area under the receiver-operating characteristics curve [AUC]) were high (CA: 88%; AUC: 0.93 [95% confidence interval (CI): 0.90 to 0.96]). However, when assessed according to microcirculatory status, a significantly lower CA and AUC of QFR were found in the high-IMR group as compared with the low-IMR group (CA: 76% vs. 92%; p < 0.001; AUC: 0.88 [95% CI: 0.79 to 0.94] vs. 0.96 [95% CI: 0.92 to 0.98]; p < 0.05). Compared with angiographic assessment, QFR increased by 0.20 (p < 0.001) and by 0.16 (p < 0.001) the AUC of %DS in low- and high-IMR groups, respectively. Independent predictors of misclassification between QFR and FFR were high IMR and acute coronary syndrome. CONCLUSIONS: CMD decreases the diagnostic performance of QFR. However, even in th
- Published
- 2018
197. Ultrafast terahertz field control of electronic and structural interactions in vanadium dioxide
- Author
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Massachusetts Institute of Technology. Department of Chemistry, Hwang, Harold Y., Brandt, Nathaniel Curran, Nelson, Keith Adam, Gray, A. X., Hoffmann, M. C., Jeong, J., Aetukuri, N. P., Zhu, D., Wen, H., Sternbach, A. J., Bonetti, S., Reid, A. H., Kukreja, R., Graves, C., Wang, T., Granitzka, P., Chen, Z., Higley, D. J., Chase, T., Jal, E., Abreu, E., Liu, M. K., Weng, T.-C., Sokaras, D., Nordlund, D., Chollet, M., Alonso-Mori, R., Lemke, H., Glownia, J. M., Trigo, M., Zhu, Y., Ohldag, H., Freeland, J. W., Samant, M. G., Berakdar, J., Averitt, R. D., Parkin, S. S. P., Dürr, H. A., Massachusetts Institute of Technology. Department of Chemistry, Hwang, Harold Y., Brandt, Nathaniel Curran, Nelson, Keith Adam, Gray, A. X., Hoffmann, M. C., Jeong, J., Aetukuri, N. P., Zhu, D., Wen, H., Sternbach, A. J., Bonetti, S., Reid, A. H., Kukreja, R., Graves, C., Wang, T., Granitzka, P., Chen, Z., Higley, D. J., Chase, T., Jal, E., Abreu, E., Liu, M. K., Weng, T.-C., Sokaras, D., Nordlund, D., Chollet, M., Alonso-Mori, R., Lemke, H., Glownia, J. M., Trigo, M., Zhu, Y., Ohldag, H., Freeland, J. W., Samant, M. G., Berakdar, J., Averitt, R. D., Parkin, S. S. P., and Dürr, H. A.
- Abstract
Vanadium dioxide (VO₂), an archetypal correlated-electron material, undergoes an insulator-metal transition near room temperature that exhibits electron-correlation-driven and structurally driven physics. Using ultrafast temperature- and fluence-dependent optical spectroscopy and x-ray scattering, we show that multiple interrelated electronic and structural processes in the nonequilibrium dynamics in VO₂ can be disentangled in the time domain. Specifically, following intense subpicosecond terahertz (THz) electric-field excitation, a partial collapse of the insulating gap occurs within the first picosecond. At temperatures sufficiently close to the transition temperature and for THz peak fields above a threshold of approximately 1 MV/cm, this electronic reconfiguration initiates a change in lattice symmetry taking place on a slower timescale. We identify the kinetic energy increase of electrons tunneling in the strong electric field as the driving force, illustrating a promising method to control electronic and structural interactions in correlated materials on an ultrafast timescale., United States. Office of Naval Research (Grant N00014-13-1-0509), National Science Foundation (U.S.) (Grant CHE-1111557)
- Published
- 2018
198. A Wildly Flickering Jet in the Black Hole X-Ray Binary MAXI J1535-571
- Author
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Cristina Baglio, M., Russell, D., Casella, P., Al Noori, H., Al Yazeedi, A., Belloni, T., Buckley, D., Cadolle Bel, M., Ceccobello, C., Corbel, S., Coti Zelati, F., Díaz Trigo, M., Fender, R., Gallo, E., Gandhi, P., Homan, J., Koljonen, K., Lewis, F., Maccarone, T., Malzac, J., Markoff, S., Miller-Jones, James, O'Brien, K., Russell, T., Saikia, P., Shahbaz, T., Sivakoff, G., Soria, Roberto, Testa, V., Tetarenko, A., Van Den Ancker, M., Vincentelli, F., Cristina Baglio, M., Russell, D., Casella, P., Al Noori, H., Al Yazeedi, A., Belloni, T., Buckley, D., Cadolle Bel, M., Ceccobello, C., Corbel, S., Coti Zelati, F., Díaz Trigo, M., Fender, R., Gallo, E., Gandhi, P., Homan, J., Koljonen, K., Lewis, F., Maccarone, T., Malzac, J., Markoff, S., Miller-Jones, James, O'Brien, K., Russell, T., Saikia, P., Shahbaz, T., Sivakoff, G., Soria, Roberto, Testa, V., Tetarenko, A., Van Den Ancker, M., and Vincentelli, F.
- Abstract
We report on the results of optical, near-infrared (NIR), and mid-infrared observations of the black hole X-ray binary candidate (BHB) MAXI J1535-571 during its 2017/2018 outburst. During the first part of the outburst (MJD 58004-58012), the source shows an optical-NIR spectrum that is consistent with an optically thin synchrotron power law from a jet. After MJD 58015, however, the source faded considerably, the drop in flux being much more evident at lower frequencies. Before the fading, we measure a dereddened flux density of 100 mJy in the mid-infrared, making MAXI J1535-571 one of the brightest mid-infrared BHBs known so far. A significant softening of the X-ray spectrum is evident contemporaneous with the infrared fade. We interpret it as being due to the suppression of the jet emission, similar to the accretion-ejection coupling seen in other BHBs. However, MAXI J1535-571 did not transition smoothly to the soft state, instead showing X-ray hardness deviations associated with infrared flaring. We also present the first mid-IR variability study of a BHB on minute timescales, with a fractional rms variability of the light curves of ~15%-22%, which is similar to that expected from the internal shock jet model, and much higher than the optical fractional rms (?7%). These results represent an excellent case of multiwavelength jet spectral timing and demonstrate how rich, multiwavelength time-resolved data of X-ray binaries over accretion state transitions can help in refining models of the disk-jet connection and jet launching in these systems.
- Published
- 2018
199. The evolving jet spectrum of the neutron star X-ray binary Aql X-1 in transitional states during its 2016 outburst
- Author
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Díaz Trigo, M., Altamirano, D., Dinçer, T., Miller-Jones, James, Russell, D., Sanna, A., Bailyn, C., Lewis, F., Migliari, S., Rahoui, F., Díaz Trigo, M., Altamirano, D., Dinçer, T., Miller-Jones, James, Russell, D., Sanna, A., Bailyn, C., Lewis, F., Migliari, S., and Rahoui, F.
- Abstract
We report on quasi-simultaneous observations from radio to X-ray frequencies of the neutron star X-ray binary Aql X-1 over accretion state transitions during its 2016 outburst. All the observations show radio to millimetre spectra consistent with emission from a jet, with a spectral break from optically thick to optically thin synchrotron emission that decreases from ~100 GHz to <5.5 GHz during the transition from a hard to a soft accretion state. The 5.5 GHz radio flux density as the source reaches the soft state, 0.82 ± 0.03 mJy, is the highest recorded to date for this source. During the decay of the outburst, the jet spectral break is detected again at a frequency of ~30-100 GHz. The flux density is 0.75 ± 0.03 mJy at 97.5 GHz at this stage. This is the first time that a change in the frequency of the jet break of a neutron star X-ray binary has been measured, indicating that the processes at play in black holes are also present in neutron stars, supporting the idea that the internal properties of the jet rely most critically on the conditions of the accretion disc and corona around the compact object, rather than the black hole mass or spin or the neutron star surface or magnetic field.
- Published
- 2018
200. Detection of Three Allelic Variants in the Rabbit Growth Hormone Gene
- Author
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C. Cattáneo, A., S. Trigo, M., O. Perez, L., A. Cordiviola, C., and G. Antonini, A.
- Subjects
Animal Production ,FOS: Biological sciences ,FOS: Animal and dairy science ,Genetics ,Single nucleotide polymorphism - Abstract
Background: The aim of this study was to identify molecular variants in a DNA fragment of the rabbit growth hormone gene and assess their relative contribution in trials with different dietary protein sources and protein levels. We studied 52 rabbits from 22 matings at the Experimental Unit of the School of Agricultural Sciences and Forestry, National University of La Plata. Diets contained two protein levels (14 and 17%) and three protein sources (meat, fish and feather meal). We evaluated the different single nucleotide polymorphism (SNP) alleles and existing genotypes, and recorded the following productive variables: weaning weight (WW), weight at 45 days (W45), weight at slaughter (WS) and hot carcass weight (HCW). Results; Three SNP variants (c.-49C>A, c.-33A>G and c.66G>A) were detected in the DNA fragment analyzed with two alleles. Whereas c.-49C>A (CC, AC) and c.66G>A (GG, AG) had only two genotypes, and C-33A> G had the three possible ones. Molecular variants were in equilibrium and two showed association (pA alleles associated with the growth hormone gene. Conclusions: The results reported in this study show the greater impact of changes in the levels and sources of protein in the diet on the percentage of variation in productivity than the presence or absence of a particular allele.Read Complete Article at ijSciences: V62017031208 AND DOI: http://dx.doi.org/10.18483/ijSci.1208
- Published
- 2017
- Full Text
- View/download PDF
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