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5,279 results on '"Titus, M."'

152. Deformation-Induced Planar Defects in Immm Ni2(Cr, Mo, W) Strengthened HAYNES® 244® Superalloy.

Author

Mann, T. R., Fahrmann, M. G., and Titus, M. S.

Subjects
HEAT resistant alloys, CREEP (Materials), STRAIN rate, SUPERLATTICES, ANTIPHASE boundaries, TRANSMISSION electron microscopy
Abstract

Precipitate shearing mechanisms during quasi-static elevated temperature tensile deformation and high temperature creep of Immm Ni2(Cr, Mo, W) strengthened HAYNES® 244® alloy have been investigated. Interrupted tensile tests from room temperature to 760 °C (1400 °F) and creep tests at 138 to 693 MPa (20 to 100 ksi) and 649 °C to 760 °C (1200 °F to 1400 °F) were conducted to experimentally determine the active deformation mechanisms under relevant operating conditions. Stacking faults were observed to form in precipitates at the start of deformation by transmission electron microscopy diffraction contrast analysis. During subsequent deformation in these conditions, these stacking faults thickened into deformation microtwins at higher strains to accommodate plastic strain, which is contrary to many other Ni-based alloy systems where superlattice intrinsic and extrinsic stacking faults or coupled antiphase boundary shearing take place. This microtwinning deformation offers unique advantages to ductility and prevents debits in yield strength due to over aging. Microtwinning was observed across all strain rates, stresses, and temperatures investigated. The relative fault energies for the formation of these planar defects are discussed and compared to Density Functional Theory calculations. [ABSTRACT FROM AUTHOR]

Published
2023
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153. Roles for the RNA-Binding Protein Caper in Reproductive Output in Drosophila melanogaster.

Author

Tixtha, Erika J., Super, Meg K., Titus, M. Brandon, Bono, Jeremy M., and Olesnicky, Eugenia C.

Subjects
RNA-binding proteins, DROSOPHILA melanogaster, GENETIC regulation, OVARIAN follicle, NERVOUS system, EGGS
Abstract

RNA binding proteins (RBPs) play a fundamental role in the post-transcriptional regulation of gene expression within the germline and nervous system. This is underscored by the prevalence of mutations within RBP-encoding genes being implicated in infertility and neurological disease. We previously described roles for the highly conserved RBP Caper in neurite morphogenesis in the Drosophila larval peripheral system and in locomotor behavior. However, caper function has not been investigated outside the nervous system, although it is widely expressed in many different tissue types during embryogenesis. Here, we describe novel roles for Caper in fertility and mating behavior. We find that Caper is expressed in ovarian follicles throughout oogenesis but is dispensable for proper patterning of the egg chamber. Additionally, reduced caper function, through either a genetic lesion or RNA interference-mediated knockdown of caper in the female germline, results in females laying significantly fewer eggs than their control counterparts. Moreover, this phenotype is exacerbated with age. caper dysfunction also results in partial embryonic and larval lethality. Given that caper is highly conserved across metazoa, these findings may also be relevant to vertebrates. [ABSTRACT FROM AUTHOR]

Published
2023
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156. Phase separating RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions

Author

Mrityunjoy Kar, Furqan Dar, Timothy J. Welsh, Laura Vogel, Ralf Kühnemuth, Anupa Majumdar, Georg Krainer, Titus M. Franzmann, Simon Alberti, Claus A. M. Seidel, Tuomas P.J. Knowles, Anthony A. Hyman, and Rohit V. Pappu

Abstract

Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation, especially at low endogenous concentrations found in cells, are thought to follow the tenets of classical nucleation theory describing a sharp transition between a dense phase and a dilute phase characterized by dispersed monomers. Here, we usedin vitrobiophysical studies to study subsaturated solutions of phase separating RNA binding proteins with intrinsically disordered prion like domains (PLDs) and RNA binding domains (RBDs). Surprisingly, we find that subsaturated solutions are characterized by heterogeneous distributions of clusters comprising tens to hundreds of molecules. These clusters also include low abundance mesoscale species that are several hundreds of nanometers in diameter. Our results show that cluster formation in subsaturated solutions and phase separation in supersaturated solutions are strongly coupled via sequence-encoded interactions. Interestingly, however, cluster formation and phase separation can be decoupled from one another using solutes that impact the solubilities of phase separating proteins. They can also be decoupled by specific types of mutations. Overall, our findings implicate the presence of distinct, sequence-specific energy scales that contribute to the overall phase behaviors of RNA binding proteins. We discuss our findings in the context of theories of associative polymers.Significance StatementMembraneless biomolecular condensates are molecular communities with distinct compositional preferences and functions. Considerable attention has focused on phase separation as the process that gives rise to condensates. Here, we show that subsaturated solutions of RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions. The formation of clusters in subsaturated solutions and condensates in supersaturated solution are coupled through sequence-specific interactions. Given the low endogenous concentrations of phase separating proteins, our findings suggest that clusters in subsaturated conditions might be of functional relevance in cells.

Published
2022
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160. Correction: Deformation-Induced Planar Defects in Immm Ni2(Cr, Mo, W) Strengthened HAYNES® 244® Superalloy.

Author

Mann, T. R., Fahrmann, M. G., and Titus, M. S.

Subjects
HEAT resistant alloys, ACTIVATION energy
Abstract

This document is a correction notice for an article titled "Deformation-Induced Planar Defects in Immm Ni2(Cr, Mo, W) Strengthened HAYNES® 244® Superalloy" published in the journal Metallurgical & Materials Transactions. The correction involves updating Figure 13 in the article to improve the color scheme and enhance readers' understanding of the colored precipitates in relation to the plotted data. The corrected figure includes a graph showing interactions with different types of matrix dislocations and DFT calculations of slip pathways. The publisher, Springer Nature, maintains a neutral stance on jurisdictional claims and institutional affiliations. [Extracted from the article]

Published
2024
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163. Pediatric Ovarian Torsion

Author

Sims, Morgan J., primary, Price, Amanda B., additional, Hirsig, Leslie E., additional, Collins, Heather R., additional, Hill, Jeanne G., additional, and Titus, M. Olivia, additional

Published
2022
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168. Performance, Nutrient Digestibility and Carcass Characteristics of Red Sokoto Goats (Bucks) fed Gmelina arborea Leaf Meal substituting Soya Bean Meal.

Author

Njidda, A. A. and Titus, M.

Subjects
GMELINA arborea, GOATS, ANIMAL carcasses, SOYBEAN as feed, DRY matter in animal nutrition, TANNINS in animal nutrition
Abstract

An experiment was conducted to determine the performance, digestibility and carcass characteristics of goats fed Gmelina arborea mixed with cowpea husk. The goats in treatment 1 received 0% Gmelina arborea leaf meal (GLM), treatment 2, 3 and 4 received 10, 20, and 30% GLM, respectively. The GLM replaced soya bean meal (SBM) weight for weight. The results reveal that T4 had significantly (p>0.05) higher values for dry matter (902.10 g Kg-1 DM), ash. (832.00 g Kg-1 DM), crude protein ((203.30 g Kg-1 DM), ether extract (42.21 g Kg-1 DM), neutral detergent fibre (601.31 g Kg-1 DM), acid detergent fibre (481.31 g Kg-1 DM), acid detergent lignin (91.19 g Kg-1 DM) and cellulose (390.12 g Kg-1 DM). The tannin content of the dietary treatments ranged from 062 - 0.82 mg g-1 DM. The dry matter intake (DMI), DMI W0.75 and Average daily gain (ADG) were significantly higher for T4. There were significant (p<0.05) effect for apparent nutrient digestibility as a result of GLM inclusion for all the dietary treatments except for ADL and NFE. The results of carcass characteristics and organ weight were significantly (p>0.05) different except for carcass length, weight of hind limb, fore limb and lungs which were not significantly (p<0.05) different. The Dressing percentage (DP) was higher for T4 than the other treatment groups. It can be concluded that feeding Gmelina arborea upto 30% level of inclusion showed marked inprovemnt for all the parameters studied. GLM can be recommended for inclusion in the diet of goats especially during the long period of dry season in the semi-arid environment. [ABSTRACT FROM AUTHOR]

Published
2023

169. Paul Titus, M. D

Author

PAUL, TITUS

Subjects
History, Humans
Published
1951

175. Unearthing the Bible : 101 Archaeological Discoveries That Bring the Bible to Life

Author

Titus M Kennedy and Titus M Kennedy

Subjects
Bible--Antiquities
Abstract

“A much-needed resource for those serious about biblical studies.” —Mark M. Yarbrough, president, Dallas Theological SeminaryThe Bible has long been dismissed as a book of myths, legends, fairy tales, and propaganda. Yet when we examine the archaeological evidence, its accuracy comes to light. In Unearthing the Bible, Dr. Titus M. Kennedy presents 101 objects that provide compelling evidence for the historical reliability of Scripture from the dawn of civilization through the early church. Gathered from more than 50 museums, private collections, and archaeological sites, these pieces not only reinforce the reliability of the biblical narratives, but also provide rich cultural insights into the ancient world. Using this visual guide, you can find context for your faith as you make your way through the Bible. Dr. Kennedy's photographs and detailed descriptions enable you to examine each piece of fascinating evidence for yourself. From the earliest tablets of creation to artifacts connected with the life and resurrection of Jesus, Unearthing the Bible shows you can be confident there is an abundance of archaeological support for the history told in the Scriptures.

Published
2020

177. Proceedings of Thematic Sessions of the Twenty-Ninth Annual Meeting of the Society of Architectural Historians. Philadelphia, Pennsylvania, 19-24 May 1976

Author

Overby, Osmund, Koshino, Takeshi, Leedy,, Walter C., Heisner, Beverly, Maass, John, Merrill, David, Bryan, John M., Robinson, Willard B., Tomlan, Michael A., Fitch, James Marston, Hosmer, Charles B., Thompson, Eleanor, Rettig, Robert B., Berkeley, Ellen Perry, Candee, Richard, Rosebrock, Ellen, Glenn, Marsha, Sande, Theodore A., DeLony, Eric N., Eaton, Leonard K., Hildebrand, Grant, Karlowicz, Titus M., Davis, Julia Finette, Roth, Leland M., Richman, Michael, Kihlstedt, Folke T., Hinderliter, Edward T., Ross, Marion D., Bruegmann, Robert, Rhoads, William B., Wilson, Richard Guy, van Zanten, David T., Goeldner, Paul, Bacon, Edmund N., Henry, Jay C., Hines, Thomas S., Schalck, Harry G., Draper, Joan E., Henry, Jean, Anderson, Stanford, Vidler, Anthony, Tzonis, Alexander, MacLeod, Robert, Bletter, Rosemarie Haag, Glassie, Henry, Brunskill, Ronald W., Richman, Irwin, Vlach, John Michael, Marshall, Howard W., Goss, Peter L., Wheaton, Rodd L., Tinkcom, Margaret B., Betts, Richard J., Magaziner, Henry J., Webster, Richard J., Thomas, George E., Teitelman, Edward, Ames, Kenneth L., Trapp, Kenneth R., Miller, R. Craig, Koch, Robert, Menz, Katherine Boyd, Willis, Peter, Belden, Frederick L., Beiswanger, William, Hammond, Charles A., and Cantor, Jay

Published
1976
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179. CAPRIN1P512L causes aberrant protein aggregation and associates with early-onset ataxia.

Author

Delle Vedove, Andrea, Natarajan, Janani, Zanni, Ginevra, Eckenweiler, Matthias, Muiños-Bühl, Anixa, Storbeck, Markus, Guillén Boixet, Jordina, Barresi, Sabina, Pizzi, Simone, Hölker, Irmgard, Körber, Friederike, Franzmann, Titus M., Bertini, Enrico S., Kirschner, Janbernd, Alberti, Simon, Tartaglia, Marco, and Wirth, Brunhilde

Abstract

CAPRIN1 is a ubiquitously expressed protein, abundant in the brain, where it regulates the transport and translation of mRNAs of genes involved in synaptic plasticity. Here we describe two unrelated children, who developed early-onset ataxia, dysarthria, cognitive decline and muscle weakness. Trio exome sequencing unraveled the identical de novo c.1535C > T (p.Pro512Leu) missense variant in CAPRIN1, affecting a highly conserved residue. In silico analyses predict an increased aggregation propensity of the mutated protein. Indeed, overexpressed CAPRIN1P512L forms insoluble ubiquitinated aggregates, sequestrating proteins associated with neurodegenerative disorders (ATXN2, GEMIN5, SNRNP200 and SNCA). Moreover, the CAPRIN1P512L mutation in isogenic iPSC-derived cortical neurons causes reduced neuronal activity and altered stress granule dynamics. Furthermore, nano-differential scanning fluorimetry reveals that CAPRIN1P512L aggregation is strongly enhanced by RNA in vitro. These findings associate the gain-of-function Pro512Leu mutation to early-onset ataxia and neurodegeneration, unveiling a critical residue of CAPRIN1 and a key role of RNA–protein interactions. [ABSTRACT FROM AUTHOR]

Published
2022
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180. Integrative Clinical and Genomic Characterization of MTAP-deficient Metastatic Urothelial Cancer.

Author

Alhalabi O, Zhu Y, Hamza A, Qiao W, Lin Y, Wang RM, Shah AY, Campbell MT, Holla V, Kamat A, Wang WL, Wang J, Chen J, Meng J, Zhang M, Bondaruk J, Titus M, Genovese G, Czerniak BA, Shaw KR, Meric-Bernstam F, Guo CC, Logothetis CJ, Siefker-Radtke A, Msaouel P, Wang L, Liu J, and Gao J

Subjects
Humans, Prognosis, Genomics, Cisplatin therapeutic use, Proportional Hazards Models, Carcinoma, Transitional Cell drug therapy
Abstract

Deficiency of MTAP (MTAP def ) mainly occurs because of homozygous loss of chromosome 9p21, which is the most common copy-number loss in metastatic urothelial cancer (mUC). We characterized the clinical and genomic features of MTAP def mUC in 193 patients treated at MD Anderson Cancer Center (MDACC) and 298 patients from the phase 2 IMvigor210 trial, which investigated atezolizumab in cisplatin-ineligible and platinum-refractory disease. In the MDACC cohort, visceral metastases were significantly more common for MTAP def (n = 48) than for MTAP-proficient (MTAP prof ; n = 145) patients (75% vs 55.2%; p = 0.02). MTAP def was associated with poor prognosis (median overall survival [mOS] 12.3 vs 20.2 mo; p = 0.007) with an adjusted hazard ratio of 1.93 (95% confidence interval 1.35-2.98). Similarly, IMvigor210 patients with MTAP lo (n = 29) had a higher incidence of visceral metastases than those with MTAP hi tumors (n = 269; 86.2% vs 72.5%; p = 0.021) and worse prognosis (mOS 8.0 vs 11.3 mo; p = 0.042). Hyperplasia-associated genes were more frequently mutated in MTAP def tumors (FGFR3: 31% vs 8%; PI3KCA: 31% vs 19%), while alterations in dysplasia-associated genes were less common in MTAP def tumors (TP53: 41% vs 67%; RB1: 0% vs 16%). Our findings support a distinct biology in MTAP def mUC that is associated with early visceral disease and worse prognosis. PATIENT SUMMARY: We investigated the outcomes for patients with the most common gene loss (MTAP gene) in metastatic cancer of the urinary tract. We found that this loss correlates with worse prognosis and a higher risk of metastasis in internal organs. There seems to be distinct tumor biology for urinary tract cancer with MTAP gene loss and this could be a potential target for treatment., (Copyright © 2021 European Association of Urology. Published by Elsevier B.V. All rights reserved.)

Published
2023
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181. Comparison of Donor Corneal Endothelial Cell Density Determined by Eye Banks and by a Central Image Analysis Reading Center Using the Same Image Analysis Method.

Author

Huang H, Benetz BA, Clover JM, Titus M, O'Brien RC, Menegay HJ, and Lass JH

Subjects
Adult, Aged, Cell Count, Corneal Endothelial Cell Loss diagnosis, Endothelial Cells, Endothelium, Corneal, Female, Humans, Middle Aged, Tissue Donors, Eye Banks, Reading
Abstract

Purpose: The purpose of this study was to evaluate agreement between eye banks (EBs) and an image analysis reading center on endothelial cell density (ECD) determinations using the same image analysis method., Methods: The Cornea Image Analysis Reading Center (CIARC) determined ECD with a single experienced analyst on EB-obtained central endothelial images from donors intended for keratoplasty from 2 eye banks, Eversight and Lions VisionGift, using the Konan center analysis method. The EBs performed ECD determination on their respective sets of images using the same analysis method with experienced eye bank technicians., Results: The mean age of the 200 donors was 54 years (range 30-75 years). Seventy (35%) of the 200 patients were women, and 57 (29%) were diabetic. The mean ECD was 10 cells/mm2 greater by the EBs than by CIARC (P = 0.39), with 95% limits of agreement of [-304 to 323 cells/mm2]. The mean difference was not substantially changed when the difference between EBs and CIARC ECD was adjusted for sex, donor age, donor diabetes, CV, HEX, number of cells analyzed, and EBs as a random effect (estimated mean difference of 20 cells/mm2 after adjustment in a linear mixed model; P = 0.73). The EB-determined preoperative ECD was within 10% of the CIARC-determined ECD for 178 (89%) image sets, with 15 (8%) higher by >10% and 7 (3%) lower by >10%., Conclusions: Well-trained eye bank technicians achieve comparable results for ECD determination with an experienced image analyst from an image analysis reading center when the same image analysis method is used., Competing Interests: The authors have no funding or conflicts of interest to disclose., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2022
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183. Abstracts of Papers Presented at the Twenty-Fourth Annual Meeting of the Society of Architectural Historians

Author

McCormick, Thomas J., Shelby, Lon R., Foster, Philip, Otto, Christian F., Cunningham, Anna K., Hinderliter, Edward T., Serenyi, Peter, Neil, J. Meredith, Fairfax, Geoffrey W., Denney, Reuel, Moss,, Roger W., Smith, Robert C., Kirkbride, Beatrice H., Schless, Nancy Halverson, Liggett, Barbara, Hawley, Henry, Hackenbroch, Yvonne, Mitter, Partha, Eaton, Leonard K., Donnelly, Marian C., Brooks, H. Allen, Teitelman, Edward, Rohrer, Judith C., Maass, John, Ames, Kenneth, Ames, Winslow, Karlowicz, Titus M., and Lewis, Arnold

Published
1971
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185. First M87 Event Horizon Telescope Results. VIII. Magnetic Field Structure near the Event Horizon

Author

Akiyama, K. Algaba, J.C. Alberdi, A. Alef, W. Anantua, R. Asada, K. Azulay, R. Baczko, A.-K. Ball, D. Baloković, M. Barrett, J. Benson, B.A. Bintley, D. Blackburn, L. Blundell, R. Boland, W. Bouman, K.L. Bower, G.C. Boyce, H. Bremer, M. Brinkerink, C.D. Brissenden, R. Britzen, S. Broderick, A.E. Broguiere, D. Bronzwaer, T. Byun, D.-Y. Carlstrom, J.E. Chael, A. Chan, C.-K. Chatterjee, S. Chatterjee, K. Chen, M.-T. Chen, Y. Chesler, P.M. Cho, I. Christian, P. Conway, J.E. Cordes, J.M. Crawford, T.M. Crew, G.B. Cruz-Osorio, A. Cui, Y. Davelaar, J. De Laurentis, M. Deane, R. Dempsey, J. Desvignes, G. Dexter, J. Doeleman, S.S. Eatough, R.P. Falcke, H. Farah, J. Fish, V.L. Fomalont, E. Ford, H.A. Fraga-Encinas, R. Friberg, P. Fromm, C.M. Fuentes, A. Galison, P. Gammie, C.F. Garciá, R. Gelles, Z. Gentaz, O. Georgiev, B. Goddi, C. Gold, R. Gómez, J.L. Gómez-Ruiz, A.I. Gu, M. Gurwell, M. Hada, K. Haggard, D. Hecht, M.H. Hesper, R. Himwich, E. Ho, L.C. Ho, P. Honma, M. Huang, C.-W.L. Huang, L. Hughes, D.H. Ikeda, S. Inoue, M. Issaoun, S. James, D.J. Jannuzi, B.T. Janssen, M. Jeter, B. Jiang, W. Jimenez-Rosales, A. Johnson, M.D. Jorstad, S. Jung, T. Karami, M. Karuppusamy, R. Kawashima, T. Keating, G.K. Kettenis, M. Kim, D.-J. Kim, J.-Y. Kim, J. Kim, J. Kino, M. Koay, J.Y. Kofuji, Y. Koch, P.M. Koyama, S. Kramer, M. Kramer, C. Krichbaum, T.P. Kuo, C.-Y. Lauer, T.R. Lee, S.-S. Levis, A. Li, Y.-R. Li, Z. Lindqvist, M. Lico, R. Lindahl, G. Liu, J. Liu, K. Liuzzo, E. Lo, W.-P. Lobanov, A.P. Loinard, L. Lonsdale, C. Lu, R.-S. Macdonald, N.R. Mao, J. Marchili, N. Markoff, S. Marrone, D.P. Marscher, A.P. Martí-Vidal, I. Matsushita, S. Matthews, L.D. Medeiros, L. Menten, K.M. Mizuno, I. Mizuno, Y. Moran, J.M. Moriyama, K. Moscibrodzka, M. Müller, C. Musoke, G. Mejiás, A.M. Michalik, D. Nadolski, A. Nagai, H. Nagar, N.M. Nakamura, M. Narayan, R. Narayanan, G. Natarajan, I. Nathanail, A. Neilsen, J. Neri, R. Ni, C. Noutsos, A. Nowak, M.A. Okino, H. Olivares, H. Ortiz-León, G.N. Oyama, T. zel, F. Palumbo, D.C.M. Park, J. Patel, N. Pen, U.-L. Pesce, D.W. Piétu, V. Plambeck, R. Popstefanija, A. Porth, O. Pötzl, F.M. Prather, B. Preciado-López, J.A. Psaltis, D. Pu, H.-Y. Ramakrishnan, V. Rao, R. Rawlings, M.G. Raymond, A.W. Rezzolla, L. Ricarte, A. Ripperda, B. Roelofs, F. Rogers, A. Ros, E. Rose, M. Roshanineshat, A. Rottmann, H. Roy, A.L. Ruszczyk, C. Rygl, K.L.J. Sánchez, S. Sánchez-Arguelles, D. Sasada, M. Savolainen, T. Schloerb, F.P. Schuster, K.-F. Shao, L. Shen, Z. Small, D. Sohn, B.W. Soohoo, J. Sun, H. Tazaki, F. Tetarenko, A.J. Tiede, P. Tilanus, R.P.J. Titus, M. Toma, K. Torne, P. Trent, T. Traianou, E. Trippe, S. Bemmel, I.V. Van Langevelde, H.J. Van Rossum, D.R. Wagner, J. Ward-Thompson, D. Wardle, J. Weintroub, J. Wex, N. Wharton, R. Wielgus, M. Wong, G.N. Wu, Q. Yoon, D. Young, A. Young, K. Younsi, Z. Yuan, F. Yuan, Y.-F. Zensus, J.A. Zhao, G.-Y. Zhao, S.-S.

Subjects
Astrophysics::High Energy Astrophysical Phenomena, Astrophysics::Cosmology and Extragalactic Astrophysics, Astrophysics::Galaxy Astrophysics
Abstract

Event Horizon Telescope (EHT) observations at 230 GHz have now imaged polarized emission around the supermassive black hole in M87 on event-horizon scales. This polarized synchrotron radiation probes the structure of magnetic fields and the plasma properties near the black hole. Here we compare the resolved polarization structure observed by the EHT, along with simultaneous unresolved observations with the Atacama Large Millimeter/submillimeter Array, to expectations from theoretical models. The low fractional linear polarization in the resolved image suggests that the polarization is scrambled on scales smaller than the EHT beam, which we attribute to Faraday rotation internal to the emission region. We estimate the average density n e ∼ 104-7 cm-3, magnetic field strength B ∼ 1-30 G, and electron temperature T e ∼ (1-12) 1010 K of the radiating plasma in a simple one-zone emission model. We show that the net azimuthal linear polarization pattern may result from organized, poloidal magnetic fields in the emission region. In a quantitative comparison with a large library of simulated polarimetric images from general relativistic magnetohydrodynamic (GRMHD) simulations, we identify a subset of physical models that can explain critical features of the polarimetric EHT observations while producing a relativistic jet of sufficient power. The consistent GRMHD models are all of magnetically arrested accretion disks, where near-horizon magnetic fields are dynamically important. We use the models to infer a mass accretion rate onto the black hole in M87 of (3-20) 10-4 M o˙ yr-1. © 2021. The Author(s). Published by the American Astronomical Society..

Published
2021

186. Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign

Author

Algaba, J.C. Anczarski, J. Asada, K. Baloković, M. Chandra, S. Cui, Y.-Z. Falcone, A.D. Giroletti, M. Goddi, C. Hada, K. Haggard, D. Jorstad, S. Kaur, A. Kawashima, T. Keating, G. Kim, J.-Y. Kino, M. Komossa, S. Kravchenko, E.V. Krichbaum, T.P. Lee, S.-S. Lu, R.-S. Lucchini, M. Markoff, S. Neilsen, J. Nowak, M.A. Park, J. Principe, G. Ramakrishnan, V. Reynolds, M.T. Sasada, M. Savchenko, S.S. Williamson, K.E. Akiyama, K. Alberdi, A. Alef, W. Anantua, R. Azulay, R. Baczko, A.-K. Ball, D. Barrett, J. Bintley, D. Benson, B.A. Blackburn, L. Blundell, R. Boland, W. Bouman, K.L. Bower, G.C. Boyce, H. Bremer, M. Brinkerink, C.D. Brissenden, R. Britzen, S. Broderick, A.E. Broguiere, D. Bronzwaer, T. Byun, D.-Y. Carlstrom, J.E. Chael, A. Chan, C.-K. Chatterjee, S. Chatterjee, K. Chen, M.-T. Chen, Y. Chesler, P.M. Cho, I. Christian, P. Conway, J.E. Cordes, J.M. Crawford, T.M. Crew, G.B. Cruz-Osorio, A. Davelaar, J. De Laurentis, M. Deane, R. Dempsey, J. Desvignes, G. Dexter, J. Doeleman, S.S. Eatough, R.P. Falcke, H. Farah, J. Fish, V.L. Fomalont, E. Ford, H.A. Fraga-Encinas, R. Friberg, P. Fromm, C.M. Fuentes, A. Galison, P. Gammie, C.F. García, R. Gentaz, O. Georgiev, B. Gold, R. Gómez, J.L. Gómez-Ruiz, A.I. Gu, M. Gurwell, M. Hecht, M.H. Hesper, R. Ho, L.C. Ho, P. Honma, M. Huang, C.-W.L. Huang, L. Hughes, D.H. Ikeda, S. Inoue, M. Issaoun, S. James, D.J. Jannuzi, B.T. Janssen, M. Jeter, B. Jiang, W. Jiménez-Rosales, A. Johnson, M.D. Jung, T. Karami, M. Karuppusamy, R. Kettenis, M. Kim, D.-J. Kim, J. Kim, J. Koay, J.Y. Kofuji, Y. Koch, P.M. Koyama, S. Kramer, M. Kramer, C. Kuo, C.-Y. Lauer, T.R. Levis, A. Li, Y.-R. Li, Z. Lindqvist, M. Lico, R. Lindahl, G. Liu, J. Liu, K. Liuzzo, E. Lo, W.-P. Lobanov, A.P. Loinard, L. Lonsdale, C. Macdonald, N.R. Mao, J. Marchili, N. Marrone, D.P. Marscher, A.P. Martí-Vidal, I. Matsushita, S. Matthews, L.D. Medeiros, L. Menten, K.M. Mizuno, I. Mizuno, Y. Moran, J.M. Moriyama, K. Moscibrodzka, M. Müller, C. Musoke, G. Mejías, A.M. Nagai, H. Nagar, N.M. Nakamura, M. Narayan, R. Narayanan, G. Natarajan, I. Nathanail, A. Neri, R. Ni, C. Noutsos, A. Okino, H. Olivares, H. Ortiz-León, G.N. Oyama, T. Ozel, F. Palumbo, D.C.M. Patel, N. Pen, U.-L. Pesce, D.W. Piétu, V. Plambeck, R. Popstefanija, A. Porth, O. Pötzl, F.M. Prather, B. Preciado-López, J.A. Psaltis, D. Pu, H.-Y. Rao, R. Rawlings, M.G. Raymond, A.W. Rezzolla, L. Ricarte, A. Ripperda, B. Roelofs, F. Rogers, A. Ros, E. Rose, M. Roshanineshat, A. Rottmann, H. Roy, A.L. Ruszczyk, C. Rygl, K.L.J. Sánchez, S. Sánchez-Arguelles, D. Savolainen, T. Schloerb, F.P. Schuster, K.-F. Shao, L. Shen, Z. Small, D. Sohn, B.W. Soohoo, J. Sun, H. Tazaki, F. Tetarenko, A.J. Tiede, P. Tilanus, R.P.J. Titus, M. Toma, K. Torne, P. Trent, T. Traianou, E. Trippe, S. Van Bemmel, I. Van Langevelde, H.J. Van Rossum, D.R. Wagner, J. Ward-Thompson, D. Wardle, J. Weintroub, J. Wex, N. Wharton, R. Wielgus, M. Wong, G.N. Wu, Q. Yoon, D. Young, A. Young, K. Younsi, Z. Yuan, F. Yuan, Y.-F. Zensus, J.A. Zhao, G.-Y. Zhao, S.-S. Principe, G. Giroletti, M. D'Ammando, F. Orienti, M. Abdalla, H. Adam, R. Aharonian, F. Benkhali, F.A. Angüner, E.O. Arcaro, C. Armand, C. Armstrong, T. Ashkar, H. Backes, M. Baghmanyan, V. Barbosa Martins, V. Barnacka, A. Barnard, M. Becherini, Y. Berge, D. Bernlöhr, K. Bi, B. Böttcher, M. Boisson, C. Bolmont, J. De Bony De Lavergne, M. Breuhaus, M. Brun, F. Brun, P. Bryan, M. Büchele, M. Bulik, T. Bylund, T. Caroff, S. Carosi, A. Casanova, S. Chand, T. Chen, A. Cotter, G. Curyło, M. Damascene Mbarubucyeye, J. Davids, I.D. Davies, J. Deil, C. Devin, J. Dewilt, P. Dirson, L. Djannati-Ataï, A. Dmytriiev, A. Donath, A. Doroshenko, V. Duffy, C. Dyks, J. Egberts, K. Eichhorn, F. Einecke, S. Emery, G. Ernenwein, J.-P. Feijen, K. Fegan, S. Fiasson, A. De Clairfontaine, G.F. Fontaine, G. Funk, S. Füßling, M. Gabici, S. Gallant, Y.A. Giavitto, G. Giunti, L. Glawion, D. Glicenstein, J.F. Gottschall, D. Grondin, M.-H. Hahn, J. Haupt, M. Hermann, G. Hinton, J.A. Hofmann, W. Hoischen, C. Holch, T.L. Holler, M. Hörbe, M. Horns, D. Huber, D. Jamrozy, M. Jankowsky, D. Jankowsky, F. Jardin-Blicq, A. Joshi, V. Jung-Richardt, I. Kasai, E. Kastendieck, M.A. Katarzyński, K. Katz, U. Khangulyan, D. Khélifi, B. Klepser, S. Kluźniak, W. Komin, N. Konno, R. Kosack, K. Kostunin, D. Kreter, M. Lamanna, G. Lemiere, A. Lemoine-Goumard, M. Lenain, J.-P. Levy, C. Lohse, T. Lypova, I. Mackey, J. Majumdar, J. Malyshev, D. Malyshev, D. Marandon, V. Marchegiani, P. Marcowith, A. Mares, A. Martí-Devesa, G. Marx, R. Maurin, G. Meintjes, P.J. Meyer, M. Moderski, R. Mohamed, M. Mohrmann, L. Montanari, A. Moore, C. Morris, P. Moulin, E. Muller, J. Murach, T. Nakashima, K. Nayerhoda, A. De Naurois, M. Ndiyavala, H. Niederwanger, F. Niemiec, J. Oakes, L. O'Brien, P. Odaka, H. Ohm, S. Olivera-Nieto, L. De Ona Wilhelmi, E. Ostrowski, M. Panter, M. Panny, S. Parsons, R.D. Peron, G. Peyaud, B. Piel, Q. Pita, S. Poireau, V. Noel, A.P. Prokhorov, D.A. Prokoph, H. Pühlhofer, G. Punch, M. Quirrenbach, A. Rauth, R. Reichherzer, P. Reimer, A. Reimer, O. Remy, Q. Renaud, M. Rieger, F. Rinchiuso, L. Romoli, C. Rowell, G. Rudak, B. Ruiz-Velasco, E. Sahakian, V. Sailer, S. Sanchez, D.A. Santangelo, A. Sasaki, M. Scalici, M. Schutte, H.M. Schwanke, U. Schwemmer, S. Seglar-Arroyo, M. Senniappan, M. Seyffert, A.S. Shafi, N. Shiningayamwe, K. Simoni, R. Sinha, A. Sol, H. Specovius, A. Spencer, S. Spir-Jacob, M. Stawarz, Ł. Sun, L. Steenkamp, R. Stegmann, C. Steinmassl, S. Steppa, C. Takahashi, T. Tavernier, T. Taylor, A.M. Terrier, R. Tiziani, D. Tluczykont, M. Tomankova, L. Trichard, C. Tsirou, M. Tuffs, R. Uchiyama, Y. Van Der Walt, D.J. Van Eldik, C. Van Rensburg, C. Van Soelen, B. Vasileiadis, G. Veh, J. Venter, C. Vincent, P. Vink, J. Völk, H.J. Vuillaume, T. Wadiasingh, Z. Wagner, S.J. Watson, J. Werner, F. White, R. Wierzcholska, A. Wong, Y.W. Yusafzai, A. Zacharias, M. Zanin, R. Zargaryan, D. Zdziarski, A.A. Zech, A. Zhu, S.J. Zorn, J. Zouari, S. Żywucka, N. Acciari, V.A. Ansoldi, S. Antonelli, L.A. Engels, A.A. Artero, M. Asano, K. Baack, D. Babić, A. Baquero, A. De Almeida, U.B. Barrio, J.A. Becerra González, J. Bednarek, W. Bellizzi, L. Bernardini, E. Bernardos, M. Berti, A. Besenrieder, J. Bhattacharyya, W. Bigongiari, C. Biland, A. Blanch, O. Bonnoli, G. Bošnjak, Ž. Busetto, G. Carosi, R. Ceribella, G. Cerruti, M. Chai, Y. Chilingarian, A. Cikota, S. Colak, S.M. Colombo, E. Contreras, J.L. Cortina, J. Covino, S. D'Amico, G. D'Elia, V. Da Vela, P. Dazzi, F. De Angelis, A. De Lotto, B. Delfino, M. Delgado, J. Delgado Mendez, C. Depaoli, D. Di Pierro, F. Di Venere, L. Do Souto Espineira, E. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Elsaesser, D. Fallah Ramazani, V. Fattorini, A. Ferrara, G. Fonseca, M.V. Font, L. Fruck, C. Fukami, S. García López, R.J. Garczarczyk, M. Gasparyan, S. Gaug, M. Giglietto, N. Giordano, F. Gliwny, P. Godinović, N. Green, J.G. Green, D. Hadasch, D. Hahn, A. Heckmann, L. Herrera, J. Hoang, J. Hrupec, D. Hütten, M. Inada, T. Inoue, S. Ishio, K. Iwamura, Y. Jiménez, I. Jormanainen, J. Jouvin, L. Kajiwara, Y. Karjalainen, M. Kerszberg, D. Kobayashi, Y. Kubo, H. Kushida, J. Lamastra, A. Lelas, D. Leone, F. Lindfors, E. Lombardi, S. Longo, F. López-Coto, R. López-Moya, M. López-Oramas, A. Loporchio, S. Machado De Oliveira Fraga, B. Maggio, C. Majumdar, P. Makariev, M. Mallamaci, M. Maneva, G. Manganaro, M. Mannheim, K. Maraschi, L. Mariotti, M. Martínez, M. Mazin, D. Menchiari, S. Mender, S. Mićanović, S. Miceli, D. Miener, T. Minev, M. Miranda, J.M. Mirzoyan, R. Molina, E. Moralejo, A. Morcuende, D. Moreno, V. Moretti, E. Neustroev, V. Nigro, C. Nilsson, K. Nishijima, K. Noda, K. Nozaki, S. Ohtani, Y. Oka, T. Otero-Santos, J. Paiano, S. Palatiello, M. Paneque, D. Paoletti, R. Paredes, J.M. Pavletić, L. Penil, P. Perennes, C. Persic, M. Moroni, P.G.P. Prandini, E. Priyadarshi, C. Puljak, I. Rhode, W. Ribó, M. Rico, J. Righi, C. Rugliancich, A. Saha, L. Sahakyan, N. Saito, T. Sakurai, S. Satalecka, K. Saturni, F.G. Schleicher, B. Schmidt, K. Schweizer, T. Sitarek, J. Šnidarić, I. Sobczynska, D. Spolon, A. Stamerra, A. Strom, D. Strzys, M. Suda, Y. Surić, T. Takahashi, M. Tavecchio, F. Temnikov, P. Terzić, T. Teshima, M. Tosti, L. Truzzi, S. Tutone, A. Ubach, S. Van Scherpenberg, J. Vanzo, G. Vazquez Acosta, M. Ventura, S. Verguilov, V. Vigorito, C.F. Vitale, V. Vovk, I. Will, M. Wunderlich, C. Zarić, D. Adams, C.B. Benbow, W. Brill, A. Capasso, M. Christiansen, J.L. Chromey, A.J. Daniel, M.K. Errando, M. Farrell, K.A. Feng, Q. Finley, J.P. Fortson, L. Furniss, A. Gent, A. Giuri, C. Hassan, T. Hervet, O. Holder, J. Hughes, G. Humensky, T.B. Jin, W. Kaaret, P. Kertzman, M. Kieda, D. Kumar, S. Lang, M.J. Lundy, M. Maier, G. Moriarty, P. Mukherjee, R. Nieto, D. Nievas-Rosillo, M. O'Brien, S. Ong, R.A. Otte, A.N. Patel, S. Pfrang, K. Pohl, M. Prado, R.R. Pueschel, E. Quinn, J. Ragan, K. Reynolds, P.T. Ribeiro, D. Richards, G.T. Roache, E. Rulten, C. Ryan, J.L. Santander, M. Sembroski, G.H. Shang, R. Weinstein, A. Williams, D.A. Williamson, T.J. Hirota, T. Cui, L. Niinuma, K. Ro, H. Sakai, N. Sawada-Satoh, S. Wajima, K. Wang, N. Liu, X. Yonekura, Y.

Subjects
Astrophysics::High Energy Astrophysical Phenomena, Astrophysics::Cosmology and Extragalactic Astrophysics
Abstract

In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations for a weakly accreting supermassive black hole of mass ∼6.5 × 109 M o˙. The EHTC also partnered with several international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at high energies, making it possible to combine core flux constraints with the more spatially precise very long baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the basic source properties, but conclude that a structured jet is necessary to explain M87's spectrum. We can exclude that the simultaneous γ-ray emission is produced via inverse Compton emission in the same region producing the EHT mm-band emission, and further conclude that the γ-rays can only be produced in the inner jets (inward of HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and secondaries cannot yet be excluded. © 2021. The Author(s). Published by the American Astronomical Society..

Published
2021

187. Constraints on black-hole charges with the 2017 EHT observations of M87∗

Author

Kocherlakota, P. Rezzolla, L. Falcke, H. Fromm, C.M. Kramer, M. Mizuno, Y. Nathanail, A. Olivares, H. Younsi, Z. Akiyama, K. Alberdi, A. Alef, W. Algaba, J.C. Anantua, R. Asada, K. Azulay, R. Baczko, A.-K. Ball, D. Baloković, M. Barrett, J. Benson, B.A. Bintley, D. Blackburn, L. Blundell, R. Boland, W. Bouman, K.L. Bower, G.C. Boyce, H. Bremer, M. Brinkerink, C.D. Brissenden, R. Britzen, S. Broderick, A.E. Broguiere, D. Bronzwaer, T. Byun, D.-Y. Carlstrom, J.E. Chael, A. Chan, C.-K. Chatterjee, S. Chatterjee, K. Chen, M.-T. Chen, Y. Chesler, P.M. Cho, I. Christian, P. Conway, J.E. Cordes, J.M. Crawford, T.M. Crew, G.B. Cruz-Osorio, A. Cui, Y. Davelaar, J. De Laurentis, M. Deane, R. Dempsey, J. Desvignes, G. Doeleman, S.S. Eatough, R.P. Farah, J. Fish, V.L. Fomalont, E. Fraga-Encinas, R. Friberg, P. Ford, H.A. Fuentes, A. Galison, P. Gammie, C.F. García, R. Gentaz, O. Georgiev, B. Goddi, C. Gold, R. Gómez, J.L. Gómez-Ruiz, A.I. Gu, M. Gurwell, M. Hada, K. Haggard, D. Hecht, M.H. Hesper, R. Ho, L.C. Ho, P. Honma, M. Huang, C.-W.L. Huang, L. Hughes, D.H. Ikeda, S. Inoue, M. Issaoun, S. James, D.J. Jannuzi, B.T. Janssen, M. Jeter, B. Jiang, W. Jimenez-Rosales, A. Johnson, M.D. Jorstad, S. Jung, T. Karami, M. Karuppusamy, R. Kawashima, T. Keating, G.K. Kettenis, M. Kim, D.-J. Kim, J.-Y. Kim, J. Kim, J. Kino, M. Koay, J.Y. Kofuji, Y. Koch, P.M. Koyama, S. Kramer, C. Krichbaum, T.P. Kuo, C.-Y. Lauer, T.R. Lee, S.-S. Levis, A. Li, Y.-R. Li, Z. Lindqvist, M. Lico, R. Lindahl, G. Liu, J. Liu, K. Liuzzo, E. Lo, W.-P. Lobanov, A.P. Loinard, L. Lonsdale, C. Lu, R.-S. Macdonald, N.R. Mao, J. Marchili, N. Markoff, S. Marrone, D.P. Marscher, A.P. Martí-Vidal, I. Matsushita, S. Matthews, L.D. Medeiros, L. Menten, K.M. Mizuno, I. Moran, J.M. Moriyama, K. Moscibrodzka, M. Müller, C. Musoke, G. Mejías, A.M. Nagai, H. Nagar, N.M. Nakamura, M. Narayan, R. Narayanan, G. Natarajan, I. Neilsen, J. Neri, R. Ni, C. Noutsos, A. Nowak, M.A. Okino, H. Ortiz-León, G.N. Oyama, T. Özel, F. Palumbo, D.C.M. Park, J. Patel, N. Pen, U.-L. Pesce, D.W. Piétu, V. Plambeck, R. Popstefanija, A. Porth, O. Pötzl, F.M. Prather, B. Preciado-López, J.A. Psaltis, D. Pu, H.-Y. Ramakrishnan, V. Rao, R. Rawlings, M.G. Raymond, A.W. Ricarte, A. Ripperda, B. Roelofs, F. Rogers, A. Ros, E. Rose, M. Roshanineshat, A. Rottmann, H. Roy, A.L. Ruszczyk, C. Rygl, K.L.J. Sánchez, S. Sánchez-Arguelles, D. Sasada, M. Savolainen, T. Schloerb, F.P. Schuster, K.-F. Shao, L. Shen, Z. Small, D. Sohn, B.W. Soohoo, J. Sun, H. Tazaki, F. Tetarenko, A.J. Tiede, P. Tilanus, R.P.J. Titus, M. Toma, K. Torne, P. Trent, T. Traianou, E. Trippe, S. Van Bemmel, I. Van Langevelde, H.J. Van Rossum, D.R. Wagner, J. Ward-Thompson, D. Wardle, J. Weintroub, J. Wex, N. Wharton, R. Wielgus, M. Wong, G.N. Wu, Q. Yoon, D. Young, A. Young, K. Yuan, F. Yuan, Y.-F. Zensus, J.A. Zhao, G.-Y. Zhao, S.-S. (EHT Collaboration)

Subjects
General Relativity and Quantum Cosmology, Astrophysics::High Energy Astrophysical Phenomena
Abstract

Our understanding of strong gravity near supermassive compact objects has recently improved thanks to the measurements made by the Event Horizon Telescope (EHT). We use here the M87∗ shadow size to infer constraints on the physical charges of a large variety of nonrotating or rotating black holes. For example, we show that the quality of the measurements is already sufficient to rule out that M87∗ is a highly charged dilaton black hole. Similarly, when considering black holes with two physical and independent charges, we are able to exclude considerable regions of the space of parameters for the doubly-charged dilaton and the Sen black holes. © 2021 authors. Published by the American Physical Society.

Published
2021

188. Event Horizon Telescope observations of the jet launching and collimation in Centaurus A

Author

Janssen, M. Falcke, H. Kadler, M. Ros, E. Wielgus, M. Akiyama, K. Baloković, M. Blackburn, L. Bouman, K.L. Chael, A. Chan, C.-K. Chatterjee, K. Davelaar, J. Edwards, P.G. Fromm, C.M. Gómez, J.L. Goddi, C. Issaoun, S. Johnson, M.D. Kim, J. Koay, J.Y. Krichbaum, T.P. Liu, J. Liuzzo, E. Markoff, S. Markowitz, A. Marrone, D.P. Mizuno, Y. Müller, C. Ni, C. Pesce, D.W. Ramakrishnan, V. Roelofs, F. Rygl, K.L.J. van Bemmel, I. Alberdi, A. Alef, W. Algaba, J.C. Anantua, R. Asada, K. Azulay, R. Baczko, A.-K. Ball, D. Barrett, J. Benson, B.A. Bintley, D. Blundell, R. Boland, W. Bower, G.C. Boyce, H. Bremer, M. Brinkerink, C.D. Brissenden, R. Britzen, S. Broderick, A.E. Broguiere, D. Bronzwaer, T. Byun, D.-Y. Carlstrom, J.E. Chatterjee, S. Chen, M.-T. Chen, Y. Chesler, P.M. Cho, I. Christian, P. Conway, J.E. Cordes, J.M. Crawford, T.M. Crew, G.B. Cruz-Osorio, A. Cui, Y. De Laurentis, M. Deane, R. Dempsey, J. Desvignes, G. Dexter, J. Doeleman, S.S. Eatough, R.P. Farah, J. Fish, V.L. Fomalont, E. Ford, H.A. Fraga-Encinas, R. Friberg, P. Fuentes, A. Galison, P. Gammie, C.F. García, R. Gelles, Z. Gentaz, O. Georgiev, B. Gold, R. Gómez-Ruiz, A.I. Gu, M. Gurwell, M. Hada, K. Haggard, D. Hecht, M.H. Hesper, R. Himwich, E. Ho, L.C. Ho, P. Honma, M. Huang, C.-W.L. Huang, L. Hughes, D.H. Ikeda, S. Inoue, M. James, D.J. Jannuzi, B.T. Jeter, B. Jiang, W. Jimenez-Rosales, A. Jorstad, S. Jung, T. Karami, M. Karuppusamy, R. Kawashima, T. Keating, G.K. Kettenis, M. Kim, D.-J. Kim, J.-Y. Kim, J. Kino, M. Kofuji, Y. Koyama, S. Kramer, M. Kramer, C. Kuo, C.-Y. Lauer, T.R. Lee, S.-S. Levis, A. Li, Y.-R. Li, Z. Lindqvist, M. Lico, R. Lindahl, G. Liu, K. Lo, W.-P. Lobanov, A.P. Loinard, L. Lonsdale, C. Lu, R.-S. MacDonald, N.R. Mao, J. Marchili, N. Marscher, A.P. Martí-Vidal, I. Matsushita, S. Matthews, L.D. Medeiros, L. Menten, K.M. Mizuno, I. Moran, J.M. Moriyama, K. Moscibrodzka, M. Musoke, G. Mejías, A.M. Nagai, H. Nagar, N.M. Nakamura, M. Narayan, R. Narayanan, G. Natarajan, I. Nathanail, A. Neilsen, J. Neri, R. Noutsos, A. Nowak, M.A. Okino, H. Olivares, H. Ortiz-León, G.N. Oyama, T. Özel, F. Palumbo, D.C.M. Park, J. Patel, N. Pen, U.-L. Piétu, V. Plambeck, R. PopStefanija, A. Porth, O. Pötzl, F.M. Prather, B. Preciado-López, J.A. Psaltis, D. Pu, H.-Y. Rao, R. Rawlings, M.G. Raymond, A.W. Rezzolla, L. Ricarte, A. Ripperda, B. Rogers, A. Rose, M. Roshanineshat, A. Rottmann, H. Roy, A.L. Ruszczyk, C. Sánchez, S. Sánchez-Arguelles, D. Sasada, M. Savolainen, T. Schloerb, F.P. Schuster, K.-F. Shao, L. Shen, Z. Small, D. Sohn, B.W. SooHoo, J. Sun, H. Tazaki, F. Tetarenko, A.J. Tiede, P. Tilanus, R.P.J. Titus, M. Torne, P. Trent, T. Traianou, E. Trippe, S. van Bemmel, I. van Langevelde, H.J. van Rossum, D.R. Wagner, J. Ward-Thompson, D. Wardle, J. Weintroub, J. Wex, N. Wharton, R. Wong, G.N. Wu, Q. Yoon, D. Young, A. Young, K. Younsi, Z. Yuan, F. Yuan, Y.-F. Zensus, J.A. Zhao, G.-Y. Zhao, S.-S. The Event Horizon Telescope Collaboration

Abstract

Very-long-baseline interferometry (VLBI) observations of active galactic nuclei at millimetre wavelengths have the power to reveal the launching and initial collimation region of extragalactic radio jets, down to 10–100 gravitational radii (rg ≡ GM/c2) scales in nearby sources1. Centaurus A is the closest radio-loud source to Earth2. It bridges the gap in mass and accretion rate between the supermassive black holes (SMBHs) in Messier 87 and our Galactic Centre. A large southern declination of −43° has, however, prevented VLBI imaging of Centaurus A below a wavelength of 1 cm thus far. Here we show the millimetre VLBI image of the source, which we obtained with the Event Horizon Telescope at 228 GHz. Compared with previous observations3, we image the jet of Centaurus A at a tenfold higher frequency and sixteen times sharper resolution and thereby probe sub-lightday structures. We reveal a highly collimated, asymmetrically edge-brightened jet as well as the fainter counterjet. We find that the source structure of Centaurus A resembles the jet in Messier 87 on ~500 rg scales remarkably well. Furthermore, we identify the location of Centaurus A’s SMBH with respect to its resolved jet core at a wavelength of 1.3 mm and conclude that the source’s event horizon shadow4 should be visible at terahertz frequencies. This location further supports the universal scale invariance of black holes over a wide range of masses5,6. © 2021, The Author(s).

Published
2021

189. Polarimetric Properties of Event Horizon Telescope Targets from ALMA

Author

Goddi, C. Martí-Vidal, I. Messias, H. Bower, G.C. Broderick, A.E. Dexter, J. Marrone, D.P. Moscibrodzka, M. Nagai, H. Algaba, J.C. Asada, K. Crew, G.B. Gómez, J.L. Impellizzeri, C.M.V. Janssen, M. Kadler, M. Krichbaum, T.P. Lico, R. Matthews, L.D. Nathanail, A. Ricarte, A. Ros, E. Younsi, Z. Akiyama, K. Alberdi, A. Alef, W. Anantua, R. Azulay, R. Baczko, A.-K. Ball, D. Baloković, M. Barrett, J. Benson, B.A. Bintley, D. Blackburn, L. Blundell, R. Boland, W. Bouman, K.L. Boyce, H. Bremer, M. Brinkerink, C.D. Brissenden, R. Britzen, S. Broguiere, D. Bronzwaer, T. Byun, D.-Y. Carlstrom, J.E. Chael, A. Chan, C.-K. Chatterjee, S. Chatterjee, K. Chen, M.-T. Chen, Y. Chesler, P.M. Cho, I. Christian, P. Conway, J.E. Cordes, J.M. Crawford, T.M. Cruz-Osorio, A. Cui, Y. Davelaar, J. De Laurentis, M. Deane, R. Dempsey, J. Desvignes, G. Doeleman, S.S. Eatough, R.P. Falcke, H. Farah, J. Fish, V.L. Fomalont, E. Ford, H.A. Fraga-Encinas, R. Freeman, W.T. Friberg, P. Fromm, C.M. Fuentes, A. Galison, P. Gammie, C.F. Garciá, R. Gentaz, O. Georgiev, B. Gold, R. Gómez-Ruiz, A.I. Gu, M. Gurwell, M. Hada, K. Haggard, D. Hecht, M.H. Hesper, R. Ho, L.C. Ho, P. Honma, M. Huang, C.-W.L. Huang, L. Hughes, D.H. Inoue, M. Issaoun, S. James, D.J. Jannuzi, B.T. Jeter, B. Jiang, W. Jimenez-Rosales, A. Johnson, M.D. Jorstad, S. Jung, T. Karami, M. Karuppusamy, R. Kawashima, T. Keating, G.K. Kettenis, M. Kim, D.-J. Kim, J.-Y. Kim, J. Kim, J. Kino, M. Koay, J.Y. Kofuji, Y. Koch, P.M. Koyama, S. Kramer, M. Kramer, C. Kuo, C.-Y. Lauer, T.R. Lee, S.-S. Levis, A. Li, Y.-R. Li, Z. Lindqvist, M. Lindahl, G. Liu, J. Liu, K. Liuzzo, E. Lo, W.-P. Lobanov, A.P. Loinard, L. Lonsdale, C. Lu, R.-S. Macdonald, N.R. Mao, J. Marchili, N. Markoff, S. Marscher, A.P. Matsushita, S. Medeiros, L. Menten, K.M. Mizuno, I. Mizuno, Y. Moran, J.M. Moriyama, K. Müller, C. Musoke, G. Mejiás, A.M. Nagar, N.M. Nakamura, M. Narayan, R. Narayanan, G. Natarajan, I. Neilsen, J. Neri, R. Ni, C. Noutsos, A. Nowak, M.A. Okino, H. Olivares, H. Ortiz-León, G.N. Oyama, T. zel, F. Palumbo, D.C.M. Park, J. Patel, N. Pen, U.-L. Pesce, D.W. Piétu, V. Plambeck, R. Popstefanija, A. Porth, O. Pötzl, F.M. Prather, B. Preciado-López, J.A. Psaltis, D. Pu, H.-Y. Ramakrishnan, V. Rao, R. Rawlings, M.G. Raymond, A.W. Rezzolla, L. Ripperda, B. Roelofs, F. Rogers, A. Rose, M. Roshanineshat, A. Rottmann, H. Roy, A.L. Ruszczyk, C. Rygl, K.L.J. Sánchez, S. Sánchez-Arguelles, D. Sasada, M. Savolainen, T. Schloerb, F.P. Schuster, K.-F. Shao, L. Shen, Z. Small, D. Sohn, B.W. Soohoo, J. Sun, H. Tazaki, F. Tetarenko, A.J. Tiede, P. Tilanus, R.P.J. Titus, M. Toma, K. Torne, P. Trent, T. Traianou, E. Trippe, S. Bemmel, I.V. Van Langevelde, H.J. Van Rossum, D.R. Wagner, J. Ward-Thompson, D. Wardle, J. Weintroub, J. Wex, N. Wharton, R. Wielgus, M. Wong, G.N. Wu, Q. Yoon, D. Young, A. Young, K. Yuan, F. Yuan, Y.-F. Zensus, J.A. Zhao, G.-Y. Zhao, S.-S. Bruni, G. Gopakumar, A. Hernández-Gómez, A. Herrero-Illana, R. Ingram, A. Komossa, S. Kovalev, Y.Y. Muders, D. Perucho, M. Rösch, F. Valtonen, M.

Abstract

We present the results from a full polarization study carried out with the Atacama Large Millimeter/submillimeter Array (ALMA) during the first Very Long Baseline Interferometry (VLBI) campaign, which was conducted in 2017 April in the λ3 mm and λ1.3 mm bands, in concert with the Global mm-VLBI Array (GMVA) and the Event Horizon Telescope (EHT), respectively. We determine the polarization and Faraday properties of all VLBI targets, including Sgr A∗, M87, and a dozen radio-loud active galactic nuclei (AGNs), in the two bands at several epochs in a time window of 10 days. We detect high linear polarization fractions (2%-15%) and large rotation measures (RM > 103.3-105.5 rad m-2), confirming the trends of previous AGN studies at millimeter wavelengths. We find that blazars are more strongly polarized than other AGNs in the sample, while exhibiting (on average) order-of-magnitude lower RM values, consistent with the AGN viewing angle unification scheme. For Sgr A∗ we report a mean RM of (-4.2 0.3) 105 rad m-2 at 1.3 mm, consistent with measurements over the past decade and, for the first time, an RM of (-2.1 0.1) 105 rad m-2 at 3 mm, suggesting that about half of the Faraday rotation at 1.3 mm may occur between the 3 mm photosphere and the 1.3 mm source. We also report the first unambiguous measurement of RM toward the M87 nucleus at millimeter wavelengths, which undergoes significant changes in magnitude and sign reversals on a one year timescale, spanning the range from -1.2 to 0.3 105 rad m-2 at 3 mm and -4.1 to 1.5 105 rad m-2 at 1.3 mm. Given this time variability, we argue that, unlike the case of Sgr A∗, the RM in M87 does not provide an accurate estimate of the mass accretion rate onto the black hole. We put forward a two-component model, comprised of a variable compact region and a static extended region, that can simultaneously explain the polarimetric properties observed by both the EHT (on horizon scales) and ALMA (which observes the combined emission from both components). These measurements provide critical constraints for the calibration, analysis, and interpretation of simultaneously obtained VLBI data with the EHT and GMVA. © 2021. The American Astronomical Society.

Published
2021

190. Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign

Author

Algaba, J. C., Anczarski, J., Asada, K., Baloković, M., Chandra, S., Cui, Y. -Z, Falcone, A. D., Giroletti, M., Goddi, C., Hada, K., Haggard, D., Jorstad, S., Kaur, A., Kawashima, T., Keating, G., Kim, J. -Y, Kino, M., Komossa, S., Kravchenko, E. V., Krichbaum, T. P., Lee, S. -S, Lu, R. -S, Lucchini, M., Markoff, S., Neilsen, J., Nowak, M. A., Park, J., Principe, G., Ramakrishnan, V., Reynolds, M. T., Sasada, M., Savchenko, S. S., Williamson, K. E., Akiyama, K., Alberdi, A., Alef, W., Anantua, R., Azulay, R., Baczko, A. -K, Ball, D., Barrett, J., Bintley, D., Benson, B. A., Blackburn, L., Blundell, R., Boland, W., Bouman, K. L., Bower, G. C., Boyce, H., Bremer, M., Brinkerink, C. D., Brissenden, R., Britzen, S., Broderick, A. E., Broguiere, D., Bronzwaer, T., Byun, D. -Y, Carlstrom, J. E., Chael, A., Chan, C. -K, Chatterjee, S., Chatterjee, K., Chen, M. -T, Chen, Y., Chesler, P. M., Cho, I., Christian, P., Conway, J. E., Cordes, J. M., Crawford, T. M., Crew, G. B., Cruz-Osorio, A., Davelaar, J., De Laurentis, M., Deane, R., Dempsey, J., Desvignes, G., Dexter, J., Doeleman, S. S., Eatough, R. P., Falcke, H., Farah, J., Fish, V. L., Fomalont, E., Ford, H. A., Fraga-Encinas, R., Friberg, P., Fromm, C. M., Fuentes, A., Galison, P., Gammie, C. F., García, R., Gentaz, O., Georgiev, B., Gold, R., Gómez, J. L., Gómez-Ruiz, A. I., Gu, M., Gurwell, M., Hecht, M. H., Hesper, R., Ho, L. C., Ho, P., Honma, M., Huang, C. -WL., Huang, L., Hughes, D. H., Ikeda, S., Inoue, M., Issaoun, S., James, D. J., Jannuzi, B. T., Janssen, M., Jeter, B., Jiang, W., Jiménez-Rosales, A., Johnson, M. D., Jung, T., Karami, M., Karuppusamy, R., Kettenis, M., Kim, D. -J, Kim, J., Koay, J. Y., Kofuji, Y., Koch, P. M., Koyama, S., Kramer, M., Kramer, C., Kuo, C. -Y, Lauer, T. R., Levis, A., Li, Y. -R, Li, Z., Lindqvist, M., Lico, R., Lindahl, G., Liu, J., Liu, K., Liuzzo, E., Lo, W. -P, Lobanov, A. P., Loinard, L., Lonsdale, C., Macdonald, N. R., Mao, J., Marchili, N., Marrone, D. P., Marscher, A. P., Martí-Vidal, I., Matsushita, S., Matthews, L. D., Medeiros, L., Menten, K. M., Mizuno, I., Mizuno, Y., Moran, J. M., Moriyama, K., Moscibrodzka, M., MÃŒller, C., Musoke, G., Mejías, A. M., Nagai, H., Nagar, N. M., Nakamura, M., Narayan, R., Narayanan, G., Natarajan, I., Nathanail, A., Neri, R., Ni, C., Noutsos, A., Okino, H., Olivares, H., Ortiz-León, G. N., Oyama, T., Ozel, F., Palumbo, D. C. M., Patel, N., Pen, U. -L, Pesce, D. W., Piétu, V., Plambeck, R., Popstefanija, A., Porth, O., Pötzl, F. M., Prather, B., Preciado-López, J. A., Psaltis, D., Pu, H. -Y, Rao, R., Rawlings, M. G., Raymond, A. W., Rezzolla, L., Ricarte, A., Ripperda, B., Roelofs, F., Rogers, A., Ros, E., Rose, M., Roshanineshat, A., Rottmann, H., Roy, A. L., Ruszczyk, C., Rygl, K. L. J., Sánchez, S., Sánchez-Arguelles, D., Savolainen, T., Schloerb, F. P., Schuster, K. -F, Shao, L., Shen, Z., Small, D., Sohn, B. W., Soohoo, J., Sun, H., Tazaki, F., Tetarenko, A. J., Tiede, P., Tilanus, R. P. J., Titus, M., Toma, K., Torne, P., Trent, T., Traianou, E., Trippe, S., Van Bemmel, I., Van Langevelde, H. J., Van Rossum, D. R., Wagner, J., Ward-Thompson, D., Wardle, J., Weintroub, J., Wex, N., Wharton, R., Wielgus, M., Wong, G. N., Wu, Q., Yoon, D., Young, A., Young, K., Younsi, Z., Yuan, F., Yuan, Y. -F, Zensus, J. A., Zhao, G. -Y, Zhao, S. -S, D’Ammando, F., Orienti, M., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. A., AngÃŒner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Barbosa Martins, V., Barnacka, A., Barnard, M., Becherini, Yvonne, Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., De Bony De Lavergne, M., Breuhaus, M., Brun, F., Brun, P., Bryan, M., BÃŒchele, M., Bulik, T., Bylund, Tomas, Caroff, S., Carosi, A., Casanova, S., Chand, T., Chen, A., Cotter, G., CuryÅ‚o, M., Damascene Mbarubucyeye, J., Davids, I. D., Davies, J., Deil, C., Devin, J., Dewilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P, Feijen, K., Fegan, S., Fiasson, A., De Clairfontaine, G. F., Fontaine, G., Funk, S., FÌßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H, Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., KatarzyÅ„ski, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, N., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemiere, A., Lemoine-Goumard, M., Lenain, J. -P, Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., De Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O’Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., De Ona Wilhelmi, E., Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. P., Prokhorov, D. A., Prokoph, H., PÃŒhlhofer, G., Punch, Michael, Quirrenbach, A., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., Van Der Walt, D. J., Van Eldik, C., Van Rensburg, C., Van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Y. W., Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Å»ywucka, N., Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. A., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., De Almeida, U. B., Barrio, J. A., Becerra González, J., Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., BoÅ¡njak, Åœ., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D’Amico, G., D’Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Delgado Mendez, C., Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espineira, E., Dominis Prester, D., Donini, A., Dorner, D., Doro, M., Elsaesser, D., Fallah Ramazani, V., Fattorini, A., Ferrara, G., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., García López, R. J., Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., HÃŒtten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jiménez, I., Jormanainen, J., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Machado De Oliveira Fraga, B., Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., Penil, P., Perennes, C., Persic, M., Moroni, P. G. P., Prandini, E., Priyadarshi, C., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schweizer, T., Sitarek, J., Å nidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., Van Scherpenberg, J., Vanzo, G., Vazquez Acosta, M., Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Zarić, D., Adams, C. B., Benbow, W., Brill, A., Capasso, M., Christiansen, J. L., Chromey, A. J., Daniel, M. K., Errando, M., Farrell, K. A., Feng, Q., Finley, J. P., Fortson, L., Furniss, A., Gent, A., Giuri, C., Hassan, T., Hervet, O., Holder, J., Hughes, G., Humensky, T. B., Jin, W., Kaaret, P., Kertzman, M., Kieda, D., Kumar, S., Lang, M. J., Lundy, M., Maier, G., Moriarty, P., Mukherjee, R., Nieto, D., Nievas-Rosillo, M., O’Brien, S., Ong, R. A., Otte, A. N., Patel, S., Pfrang, K., Pohl, M., Prado, R. R., Pueschel, E., Quinn, J., Ragan, K., Reynolds, P. T., Ribeiro, D., Richards, G. T., Roache, E., Rulten, C., Ryan, J. L., Santander, M., Sembroski, G. H., Shang, R., Weinstein, A., Williams, D. A., Williamson, T. J., Hirota, T., Cui, L., Niinuma, K., Ro, H., Sakai, N., Sawada-Satoh, S., Wajima, K., Wang, N., Liu, X., Yonekura, Y., Algaba, J. C., Anczarski, J., Asada, K., Baloković, M., Chandra, S., Cui, Y. -Z, Falcone, A. D., Giroletti, M., Goddi, C., Hada, K., Haggard, D., Jorstad, S., Kaur, A., Kawashima, T., Keating, G., Kim, J. -Y, Kino, M., Komossa, S., Kravchenko, E. V., Krichbaum, T. P., Lee, S. -S, Lu, R. -S, Lucchini, M., Markoff, S., Neilsen, J., Nowak, M. A., Park, J., Principe, G., Ramakrishnan, V., Reynolds, M. T., Sasada, M., Savchenko, S. S., Williamson, K. E., Akiyama, K., Alberdi, A., Alef, W., Anantua, R., Azulay, R., Baczko, A. -K, Ball, D., Barrett, J., Bintley, D., Benson, B. A., Blackburn, L., Blundell, R., Boland, W., Bouman, K. L., Bower, G. C., Boyce, H., Bremer, M., Brinkerink, C. D., Brissenden, R., Britzen, S., Broderick, A. E., Broguiere, D., Bronzwaer, T., Byun, D. -Y, Carlstrom, J. E., Chael, A., Chan, C. -K, Chatterjee, S., Chatterjee, K., Chen, M. -T, Chen, Y., Chesler, P. M., Cho, I., Christian, P., Conway, J. E., Cordes, J. M., Crawford, T. M., Crew, G. B., Cruz-Osorio, A., Davelaar, J., De Laurentis, M., Deane, R., Dempsey, J., Desvignes, G., Dexter, J., Doeleman, S. S., Eatough, R. P., Falcke, H., Farah, J., Fish, V. L., Fomalont, E., Ford, H. A., Fraga-Encinas, R., Friberg, P., Fromm, C. M., Fuentes, A., Galison, P., Gammie, C. F., García, R., Gentaz, O., Georgiev, B., Gold, R., Gómez, J. L., Gómez-Ruiz, A. I., Gu, M., Gurwell, M., Hecht, M. H., Hesper, R., Ho, L. C., Ho, P., Honma, M., Huang, C. -WL., Huang, L., Hughes, D. H., Ikeda, S., Inoue, M., Issaoun, S., James, D. J., Jannuzi, B. T., Janssen, M., Jeter, B., Jiang, W., Jiménez-Rosales, A., Johnson, M. D., Jung, T., Karami, M., Karuppusamy, R., Kettenis, M., Kim, D. -J, Kim, J., Koay, J. Y., Kofuji, Y., Koch, P. M., Koyama, S., Kramer, M., Kramer, C., Kuo, C. -Y, Lauer, T. R., Levis, A., Li, Y. -R, Li, Z., Lindqvist, M., Lico, R., Lindahl, G., Liu, J., Liu, K., Liuzzo, E., Lo, W. -P, Lobanov, A. P., Loinard, L., Lonsdale, C., Macdonald, N. R., Mao, J., Marchili, N., Marrone, D. P., Marscher, A. P., Martí-Vidal, I., Matsushita, S., Matthews, L. D., Medeiros, L., Menten, K. M., Mizuno, I., Mizuno, Y., Moran, J. M., Moriyama, K., Moscibrodzka, M., MÃŒller, C., Musoke, G., Mejías, A. M., Nagai, H., Nagar, N. M., Nakamura, M., Narayan, R., Narayanan, G., Natarajan, I., Nathanail, A., Neri, R., Ni, C., Noutsos, A., Okino, H., Olivares, H., Ortiz-León, G. N., Oyama, T., Ozel, F., Palumbo, D. C. M., Patel, N., Pen, U. -L, Pesce, D. W., Piétu, V., Plambeck, R., Popstefanija, A., Porth, O., Pötzl, F. M., Prather, B., Preciado-López, J. A., Psaltis, D., Pu, H. -Y, Rao, R., Rawlings, M. G., Raymond, A. W., Rezzolla, L., Ricarte, A., Ripperda, B., Roelofs, F., Rogers, A., Ros, E., Rose, M., Roshanineshat, A., Rottmann, H., Roy, A. L., Ruszczyk, C., Rygl, K. L. J., Sánchez, S., Sánchez-Arguelles, D., Savolainen, T., Schloerb, F. P., Schuster, K. -F, Shao, L., Shen, Z., Small, D., Sohn, B. W., Soohoo, J., Sun, H., Tazaki, F., Tetarenko, A. J., Tiede, P., Tilanus, R. P. J., Titus, M., Toma, K., Torne, P., Trent, T., Traianou, E., Trippe, S., Van Bemmel, I., Van Langevelde, H. J., Van Rossum, D. R., Wagner, J., Ward-Thompson, D., Wardle, J., Weintroub, J., Wex, N., Wharton, R., Wielgus, M., Wong, G. N., Wu, Q., Yoon, D., Young, A., Young, K., Younsi, Z., Yuan, F., Yuan, Y. -F, Zensus, J. A., Zhao, G. -Y, Zhao, S. -S, D’Ammando, F., Orienti, M., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. A., AngÃŒner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Barbosa Martins, V., Barnacka, A., Barnard, M., Becherini, Yvonne, Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., De Bony De Lavergne, M., Breuhaus, M., Brun, F., Brun, P., Bryan, M., BÃŒchele, M., Bulik, T., Bylund, Tomas, Caroff, S., Carosi, A., Casanova, S., Chand, T., Chen, A., Cotter, G., CuryÅ‚o, M., Damascene Mbarubucyeye, J., Davids, I. D., Davies, J., Deil, C., Devin, J., Dewilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P, Feijen, K., Fegan, S., Fiasson, A., De Clairfontaine, G. F., Fontaine, G., Funk, S., FÌßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H, Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., KatarzyÅ„ski, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, N., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemiere, A., Lemoine-Goumard, M., Lenain, J. -P, Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., De Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O’Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., De Ona Wilhelmi, E., Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. P., Prokhorov, D. A., Prokoph, H., PÃŒhlhofer, G., Punch, Michael, Quirrenbach, A., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., Van Der Walt, D. J., Van Eldik, C., Van Rensburg, C., Van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Y. W., Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Å»ywucka, N., Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. A., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., De Almeida, U. B., Barrio, J. A., Becerra González, J., Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., BoÅ¡njak, Åœ., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D’Amico, G., D’Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Delgado Mendez, C., Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espineira, E., Dominis Prester, D., Donini, A., Dorner, D., Doro, M., Elsaesser, D., Fallah Ramazani, V., Fattorini, A., Ferrara, G., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., García López, R. J., Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., HÃŒtten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jiménez, I., Jormanainen, J., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Machado De Oliveira Fraga, B., Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., Penil, P., Perennes, C., Persic, M., Moroni, P. G. P., Prandini, E., Priyadarshi, C., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schweizer, T., Sitarek, J., Å nidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., Van Scherpenberg, J., Vanzo, G., Vazquez Acosta, M., Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Zarić, D., Adams, C. B., Benbow, W., Brill, A., Capasso, M., Christiansen, J. L., Chromey, A. J., Daniel, M. K., Errando, M., Farrell, K. A., Feng, Q., Finley, J. P., Fortson, L., Furniss, A., Gent, A., Giuri, C., Hassan, T., Hervet, O., Holder, J., Hughes, G., Humensky, T. B., Jin, W., Kaaret, P., Kertzman, M., Kieda, D., Kumar, S., Lang, M. J., Lundy, M., Maier, G., Moriarty, P., Mukherjee, R., Nieto, D., Nievas-Rosillo, M., O’Brien, S., Ong, R. A., Otte, A. N., Patel, S., Pfrang, K., Pohl, M., Prado, R. R., Pueschel, E., Quinn, J., Ragan, K., Reynolds, P. T., Ribeiro, D., Richards, G. T., Roache, E., Rulten, C., Ryan, J. L., Santander, M., Sembroski, G. H., Shang, R., Weinstein, A., Williams, D. A., Williamson, T. J., Hirota, T., Cui, L., Niinuma, K., Ro, H., Sakai, N., Sawada-Satoh, S., Wajima, K., Wang, N., Liu, X., and Yonekura, Y.

Abstract

In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations for a weakly accreting supermassive black hole of mass ∌6.5 × 109 M oË™. The EHTC also partnered with several international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at high energies, making it possible to combine core flux constraints with the more spatially precise very long baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the basic source properties, but conclude that a structured jet is necessary to explain M87’s spectrum. We can exclude that the simultaneous γ-ray emission is produced via inverse Compton emission in the same region producing the EHT mm-band emission, and further conclude that the γ-rays can only be produced in the inner jets (inward of HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and secondaries cannot yet be excluded. © 2021. The Author(s). Published by the American Astronomical Society..

Published
2021
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196. Structural and functional analysis of the DEAF-1 and BS69 MYND domains.

Author

Fatiha Kateb, Helene Perrin, Konstantinos Tripsianes, Peijian Zou, Roberta Spadaccini, Matthew Bottomley, Titus M Franzmann, Johannes Buchner, Stephane Ansieau, and Michael Sattler

Subjects
Medicine, Science
Abstract

DEAF-1 is an important transcriptional regulator that is required for embryonic development and is linked to clinical depression and suicidal behavior in humans. It comprises various structural domains, including a SAND domain that mediates DNA binding and a MYND domain, a cysteine-rich module organized in a Cys(4)-Cys(2)-His-Cys (C4-C2HC) tandem zinc binding motif. DEAF-1 transcription regulation activity is mediated through interactions with cofactors such as NCoR and SMRT. Despite the important biological role of the DEAF-1 protein, little is known regarding the structure and binding properties of its MYND domain.Here, we report the solution structure, dynamics and ligand binding of the human DEAF-1 MYND domain encompassing residues 501-544 determined by NMR spectroscopy. The structure adopts a ββα fold that exhibits tandem zinc-binding sites with a cross-brace topology, similar to the MYND domains in AML1/ETO and other proteins. We show that the DEAF-1 MYND domain binds to peptides derived from SMRT and NCoR corepressors. The binding surface mapped by NMR titrations is similar to the one previously reported for AML1/ETO. The ligand binding and molecular functions of the related BS69 MYND domain were studied based on a homology model and mutational analysis. Interestingly, the interaction between BS69 and its binding partners (viral and cellular proteins) seems to require distinct charged residues flanking the predicted MYND domain fold, suggesting a different binding mode. Our findings demonstrate that the MYND domain is a conserved zinc binding fold that plays important roles in transcriptional regulation by mediating distinct molecular interactions with viral and cellular proteins.

Published
2013
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197. The eye lens chaperone [alpha]-crystallin forms defined globular assemblies

Author

Peschek, Jirka, Braun, Nathalie, Franzmann, Titus M., Georgalis, Yannis, Haslbeck, Martin, Weinkauf, Sevil, and Buchner, Johannes

Subjects
Heat shock proteins -- Physiological aspects, Heat shock proteins -- Structure, Heat shock proteins -- Research, Molecular chaperones -- Physiological aspects, Molecular chaperones -- Structure, Molecular chaperones -- Research, Science and technology
Abstract

[alpha]-Crystallins are molecular chaperones that protect vertebrate eye lens proteins from detrimental protein aggregation. [alpha]B-Crystallin, 1 of the 2 [alpha]-crystallin isoforms, is also associated with myopathies and neuropathological diseases, Despite the importance of [alpha]-crystallins in protein homeostasis, only little is known about their quaternary structures because of their seemingly polydisperse nature. Here, we analyzed the structures of recombinant [alpha]-crystallins using biophysical methods. In contrast to previous reports, we show that [alpha]B-crystallin assembles into defined oligomers consisting of 24 subunits. The 3-dimensional (3D) reconstruction of [alpha]B-crystallin by electron microscopy reveals a spherelike structure with large openings to the interior of the protein. [alpha]A-Crystallin forms, in addition to complexes of 24 subunits, also smaller oligomers and large clusters consisting of individual oligomers. This propensity might explain the previously reported polydisperse nature of [alpha]-crystallin. electron microscopy | molecular chaperone | protein aggregation | small heat shock protein | stress response

Published
2009

198. Ubiquitin protein helps cells to recover from stress

Author

Titus M. Franzmann and Simon Alberti

Subjects
Stress (mechanics), Multidisciplinary, Stress granule, Ubiquitin, biology, Chemistry, biology.protein, RNA, Cell biology
Abstract

In stressed cells, proteins and RNA molecules cluster together to form stress granules. It emerges that the small protein modifier ubiquitin is needed to disassemble stress granules in recovering cells. Disassembly of stress granules is enabled by ubiquitination.

Published
2021
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200. The conserved alternative splicing factor caper regulates neuromuscular phenotypes during development and aging

Author

Titus, M. Brandon, primary, Wright, Ethan G., additional, Bono, Jeremy M., additional, Poliakon, Andrea K., additional, Goldstein, Brandon R., additional, Super, Meg K., additional, Young, Lauren A., additional, Manaj, Melpomeni, additional, Litchford, Morgan, additional, Reist, Noreen E., additional, Killian, Darrell J., additional, and Olesnicky, Eugenia C., additional

Published
2021
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