28,447 results on '"Schirmer A"'
Search Results
152. Transcatheter aortic valve implantation in patients with significant septal hypertrophy
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Beyer, Martin, Demal, Till Joscha, Bhadra, Oliver D., Linder, Matthias, Ludwig, Sebastian, Grundmann, David, Voigtlaender-Buschmann, Lisa, Waldschmidt, Lara, Schirmer, Johannes, Schofer, Niklas, Pecha, Simon, Blankenberg, Stefan, Reichenspurner, Hermann, Conradi, Lenard, Seiffert, Moritz, and Schaefer, Andreas
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- 2024
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153. Comparison of a novel self-expanding transcatheter heart valve with two established devices for treatment of degenerated surgical aortic bioprostheses
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Nikolayevska, Olga, Conradi, Lenard, Schirmer, Johannes, Reichenspurner, Hermann, Deuschl, Florian, Blankenberg, Stefan, and Schäfer, Ulrich
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- 2024
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154. Euclid preparation. XXVII. A UV-NIR spectral atlas of compact planetary nebulae for wavelength calibration
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Euclid Collaboration, Paterson, K., Schirmer, M., Copin, Y., Cuillandre, J. -C., Gillard, W., Soto, L. A. Gutiérrez, Guzzo, L., Hoekstra, H., Kitching, T., Paltani, S., Percival, W. J., Scodeggio, M., Stanghellini, L., Appleton, P. N., Laureijs, R., Mellier, Y., Aghanim, N., Altieri, B., Amara, A., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Corcione, L., Courbin, F., Da Silva, A., Degaudenzi, H., Dinis, J., Douspis, M., Dubath, F., Dupac, X., Ferriol, S., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hornstrup, A., Hudelot, P., Jahnke, K., Kümmel, M., Kiessling, A., Kilbinger, M., Kohley, R., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Medinaceli, E., Mei, S., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Nakajima, R., Niemi, S. -M., Nightingale, J. W., Nutma, T., Padilla, C., Pasian, F., Pedersen, K., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Rix, H. -W., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Skottfelt, J., Stanco, L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Keihänen, E., Lindholm, V., Maino, D., Mauri, N., Scottez, V., Tenti, M., Zucca, E., Akrami, Y., Baccigalupi, C., Ballardini, M., Biviano, A., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Castro, T., Chambers, K. C., Cooray, A. R., Coupon, J., Courtois, H. M., Davini, S., De Lucia, G., Desprez, G., Escartin, J. A., Escoffier, S., Ferrero, I., Gabarra, L., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Magliocchetti, M., Mainetti, G., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Martins, C. J. A. P., Matthew, S., Maurin, L., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Patrizii, L., Pollack, J., Porciani, C., Potter, D., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schneider, A., Sefusatti, E., Sereno, M., Shulevski, A., Stadel, J., Steinwagner, J., Valieri, C., Valiviita, J., Veropalumbo, A., Viel, M., and Zinchenko, I. A.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The Euclid mission will conduct an extragalactic survey over 15000 deg$^2$ of the extragalactic sky. The spectroscopic channel of the Near-Infrared Spectrometer and Photometer (NISP) has a resolution of $R\sim450$ for its blue and red grisms that collectively cover the $0.93$--$1.89 $\micron;range. NISP will obtain spectroscopic redshifts for $3\times10^7$ galaxies for the experiments on galaxy clustering, baryonic acoustic oscillations, and redshift space distortion. The wavelength calibration must be accurate within $5$\AA to avoid systematics in the redshifts and downstream cosmological parameters. The NISP pre-flight dispersion laws for the grisms were obtained on the ground using a Fabry-Perot etalon. Launch vibrations, zero gravity conditions, and thermal stabilisation may alter these dispersion laws, requiring an in-flight recalibration. To this end, we use the emission lines in the spectra of compact planetary nebulae (PNe), which were selected from a PN data base. To ensure completeness of the PN sample, we developed a novel technique to identify compact and strong line emitters in Gaia spectroscopic data using the Gaia spectra shape coefficients. We obtained VLT/X-SHOOTER spectra from $0.3$ to $2.5$ \micron;for 19 PNe in excellent seeing conditions and a wide slit, mimicking Euclid's slitless spectroscopy mode but with 10 times higher spectral resolution. Additional observations of one northern PN were obtained in the $0.80$--$1.90$ \micron range with the GMOS and GNIRS instruments at the Gemini North observatory. The collected spectra were combined into an atlas of heliocentric vacuum wavelengths with a joint statistical and systematic accuracy of 0.1 \AA in the optical and 0.3 \AA in the near-infrared. The wavelength atlas and the related 1D and 2D spectra are made publicly available., Comment: Accepted in A&A
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- 2023
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155. Analyzing and Unifying Robustness Measures for Excitation Transfer Control in Spin Networks
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O'Neil, S. P., Khalid, I., Rompokos, A. A., Weidner, C. A., Langbein, F. C., Schirmer, S. G., and Jonckheere, E. A.
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Quantum Physics - Abstract
Recent achievements in quantum control have resulted in advanced techniques for designing controllers for applications in quantum communication, computing, and sensing. However, the susceptibility of such systems to noise and uncertainties necessitates robust controllers that perform effectively under these conditions to realize the full potential of quantum devices. The time-domain log-sensitivity and a recently introduced robustness infidelity measure (RIM) are two means to quantify controller robustness in quantum systems. The former can be found analytically, while the latter requires Monte-Carlo sampling. In this work, the correlation between the log-sensitivity and the RIM for evaluating the robustness of single excitation transfer fidelity in spin chains and rings in the presence of dephasing is investigated. We show that the expected differential sensitivity of the error agrees with the differential sensitivity of the RIM, where the expectation is over the error probability distribution. Statistical analysis also demonstrates that the log-sensitivity and the RIM are linked via the differential sensitivity, and that the differential sensitivity and RIM are highly concordant. This unification of two means (one analytic and one via sampling) to assess controller robustness in a variety of realistic scenarios provides a first step in unifying various tools to model and assess robustness of quantum controllers., Comment: 6 pages, 4 figures, 2 tables, comments welcome
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- 2023
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156. Lotus: Serverless In-Transit Data Processing for Edge-based Pub/Sub
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Wang, Minghe, Schirmer, Trever, Pfandzelter, Tobias, and Bermbach, David
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Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Publish-subscribe systems are a popular approach for edge-based IoT use cases: Heterogeneous, constrained edge devices can be integrated easily, with message routing logic offloaded to edge message brokers. Message processing, however, is still done on constrained edge devices. Complex content-based filtering, the transformation between data representations, or message extraction place a considerable load on these systems, and resulting superfluous message transfers strain the network. In this paper, we propose Lotus, adding in-transit data processing to an edge publish-subscribe middleware in order to offload basic message processing from edge devices to brokers. Specifically, we leverage the Function-as-a-Service paradigm, which offers support for efficient multi-tenancy, scale-to-zero, and real-time processing. With a proof-of-concept prototype of Lotus, we validate its feasibility and demonstrate how it can be used to offload sensor data transformation to the publish-subscribe messaging middleware.
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- 2023
157. Managing Data Replication and Distribution in the Fog with FReD
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Pfandzelter, Tobias, Japke, Nils, Schirmer, Trever, Hasenburg, Jonathan, and Bermbach, David
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Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
The heterogeneous, geographically distributed infrastructure of fog computing poses challenges in data replication, data distribution, and data mobility for fog applications. Fog computing is still missing the necessary abstractions to manage application data, and fog application developers need to re-implement data management for every new piece of software. Proposed solutions are limited to certain application domains, such as the IoT, are not flexible in regard to network topology, or do not provide the means for applications to control the movement of their data. In this paper, we present FReD, a data replication middleware for the fog. FReD serves as a building block for configurable fog data distribution and enables low-latency, high-bandwidth, and privacy-sensitive applications. FReD is a common data access interface across heterogeneous infrastructure and network topologies, provides transparent and controllable data distribution, and can be integrated with applications from different domains. To evaluate our approach, we present a prototype implementation of FReD and show the benefits of developing with FReD using three case studies of fog computing applications.
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- 2023
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158. Euclid preparation. XXX. Performance assessment of the NISP Red-Grism through spectroscopic simulations for the Wide and Deep surveys
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Euclid Collaboration, Gabarra, L., Mancini, C., Munoz, L. Rodriguez, Rodighiero, G., Sirignano, C., Scodeggio, M., Talia, M., Dusini, S., Gillard, W., Granett, B. R., Maiorano, E., Moresco, M., Paganin, L., Palazzi, E., Pozzetti, L., Renzi, A., Rossetti, E., Vergani, D., Allevato, V., Bisigello, L., Castignani, G., De Caro, B., Fumana, M., Ganga, K., Garilli, B., Hirschmann, M., La Franca, F., Laigle, C., Passalacqua, F., Schirmer, M., Stanco, L., Troja, A., Yung, L. Y. A., Zamorani, G., Zoubian, J., Aghanim, N., Amara, A., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Costille, A., Courbin, F., Da Silva, A., Degaudenzi, H., Dinis, J., Dubath, F., Dupac, X., Ealet, A., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Franzetti, P., Galeotta, S., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Holmes, W., Hornstrup, A., Hudelot, P., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kohley, R., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., Mei, S., Meneghetti, M., Meylan, G., Moscardini, L., Munari, E., Nichol, R. C., Niemi, S. -M., Nightingale, J., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Polenta, G., Poncet, M., Raison, F., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Saglia, R., Sapone, D., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirri, G., Surace, C., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Trifoglio, M., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Andreon, S., Aussel, H., Bardelli, S., Bolzonella, M., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Keihänen, E., Lindholm, V., Maino, D., Mauri, N., Mellier, Y., Neissner, C., Scottez, V., Tenti, M., Zucca, E., Akrami, Y., Baccigalupi, C., Ballardini, M., Bernardeau, F., Biviano, A., Borlaff, A. S., Borsato, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castro, T., Chambers, K., Cooray, A. R., Coupon, J., Courtois, H. M., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Ferrero, I., Finelli, F., Fotopoulou, S., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Muñoz, A. Jimenez, Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Martins, C. J. A. P., Matthew, S., Maurin, L., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schneider, A., Sefusatti, E., Sereno, M., Shulevski, A., Mancini, A. Spurio, Stadel, J., Steinwagner, J., Teyssier, R., Valiviita, J., Veropalumbo, A., Viel, M., and Zinchenko, I. A.
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Astrophysics - Astrophysics of Galaxies - Abstract
This work focuses on the pilot run of a simulation campaign aimed at investigating the spectroscopic capabilities of the Euclid Near-Infrared Spectrometer and Photometer (NISP), in terms of continuum and emission line detection in the context of galaxy evolutionary studies. To this purpose we constructed, emulated, and analysed the spectra of 4992 star-forming galaxies at $0.3 \leq z \leq 2.5$ using the NISP pixel-level simulator. We built the spectral library starting from public multi-wavelength galaxy catalogues, with value-added information on spectral energy distribution (SED) fitting results, and from Bruzual and Charlot (2003) stellar population templates. Rest-frame optical and near-IR nebular emission lines were included using empirical and theoretical relations. We inferred the 3.5$\sigma$ NISP red grism spectroscopic detection limit of the continuum measured in the $H$ band for star-forming galaxies with a median disk half-light radius of \ang{;;0.4} at magnitude $H= 19.5\pm0.2\,$AB$\,$mag for the Euclid Wide Survey and at $H = 20.8\pm0.6\,$AB$\,$mag for the Euclid Deep Survey. We found a very good agreement with the red grism emission line detection limit requirement for the Wide and Deep surveys. We characterised the effect of the galaxy shape on the detection capability of the red grism and highlighted the degradation of the quality of the extracted spectra as the disk size increases. In particular, we found that the extracted emission line signal to noise ratio (SNR) drops by $\sim\,$45$\%$ when the disk size ranges from \ang{;;0.25} to \ang{;;1}. These trends lead to a correlation between the emission line SNR and the stellar mass of the galaxy and we demonstrate the effect in a stacking analysis unveiling emission lines otherwise too faint to detect., Comment: 24 pages, 21 figures
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- 2023
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159. Euclid preparation. XXXII. Evaluating the weak lensing cluster mass biases using the Three Hundred Project hydrodynamical simulations
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Euclid Collaboration, Giocoli, C., Meneghetti, M., Rasia, E., Borgani, S., Despali, G., Lesci, G. F., Marulli, F., Moscardini, L., Sereno, M., Cui, W., Knebe, A., Yepes, G., Castro, T., Corasaniti, P. -S., Pires, S., Castignani, G., Ingoglia, L., Schrabback, T., Pratt, G. W., Brun, A. M. C. Le, Aghanim, N., Amendola, L., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Dinis, J., Dubath, F., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kilbinger, M., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Massey, R., Maurogordato, S., Mei, S., Merlin, E., Meylan, G., Moresco, M., Munari, E., Niemi, S. -M., Nightingale, J., Nutma, T., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Fabbian, G., Farina, M., Israel, H., Keihänen, E., Lindholm, V., Mauri, N., Neissner, C., Schirmer, M., Scottez, V., Tenti, M., Zucca, E., Akrami, Y., Baccigalupi, C., Ballardini, M., Bernardeau, F., Biviano, A., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Chambers, K. C., Cooray, A. R., Courtois, H. M., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., MU\{N}OZ, A. JIMENEZ, Joachimi, B., Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Martins, C. J. A. P., Matthew, S., Maurin, L., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Pollack, J., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schneider, A., Sefusatti, E., Shulevski, A., Mancini, A. Spurio, Stadel, J., Steinwagner, J., Valiviita, J., Veropalumbo, A., Viel, M., and Zinchenko, I. A.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
The photometric catalogue of galaxy clusters extracted from ESA Euclid data is expected to be very competitive for cosmological studies. Using state-of-the-art hydrodynamical simulations, we present systematic analyses simulating the expected weak lensing profiles from clusters in a variety of dynamic states and at wide range of redshifts. In order to derive cluster masses, we use a model consistent with the implementation within the Euclid Consortium of the dedicated processing function and find that, when jointly modelling mass and the concentration parameter of the Navarro-Frenk-White halo profile, the weak lensing masses tend to be, on average, biased low by 5-10% with respect to the true mass, up to z=0.5. Using a fixed value for the concentration $c_{200} = 3$, the mass bias is diminished below 5%, up to z=0.7, along with its relative uncertainty. Simulating the weak lensing signal by projecting along the directions of the axes of the moment of inertia tensor ellipsoid, we find that orientation matters: when clusters are oriented along the major axis, the lensing signal is boosted, and the recovered weak lensing mass is correspondingly overestimated. Typically, the weak lensing mass bias of individual clusters is modulated by the weak lensing signal-to-noise ratio, related to the redshift evolution of the number of galaxies used for weak lensing measurements: the negative mass bias tends to be larger toward higher redshifts. However, when we use a fixed value of the concentration parameter, the redshift evolution trend is reduced. These results provide a solid basis for the weak-lensing mass calibration required by the cosmological application of future cluster surveys from Euclid and Rubin., Comment: Accepted for publication in Astronomy & Astrophysics
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- 2023
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160. Euclid Preparation. XXVIII. Forecasts for ten different higher-order weak lensing statistics
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Euclid Collaboration, Ajani, V., Baldi, M., Barthelemy, A., Boyle, A., Burger, P., Cardone, V. F., Cheng, S., Codis, S., Giocoli, C., Harnois-Déraps, J., Heydenreich, S., Kansal, V., Kilbinger, M., Linke, L., Llinares, C., Martinet, N., Parroni, C., Peel, A., Pires, S., Porth, L., Tereno, I., Uhlemann, C., Vicinanza, M., Vinciguerra, S., Aghanim, N., Auricchio, N., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Di Giorgio, A. M., Dinis, J., Douspis, M., Dubath, F., Dupac, X., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Hoekstra, H., Holmes, W., Hornstrup, A., Hudelot, P., Jahnke, K., Jhabvala, M., Kümmel, M., Kitching, T., Kunz, M., Kurki-Suonio, H., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Mei, S., Mellier, Y., Meneghetti, M., Moresco, M., Moscardini, L., Niemi, S. -M., Nightingale, J., Nutma, T., Padilla, C., Paltani, S., Pedersen, K., Pettorino, V., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Schrabback, T., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Fabbian, G., Farina, M., Graciá-Carpio, J., Keihänen, E., Lindholm, V., Maino, D., Mauri, N., Neissner, C., Schirmer, M., Scottez, V., Zucca, E., Akrami, Y., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Blanchard, A., Borgani, S., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Castro, T., Chambers, K. C., Cooray, A. R., Coupon, J., Courtois, H. M., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Ferrero, I., Finelli, F., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Muñoz, A. Jimenez, Joachimi, B., Kajava, J. J. E., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maurin, L., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Popa, V., Potter, D., Pourtsidou, A., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schneider, A., Sefusatti, E., Sereno, M., Shulevski, A., Mancini, A. Spurio, Steinwagner, J., Teyssier, R., Valiviita, J., Veropalumbo, A., Viel, M., and Zinchenko, I. A.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Recent cosmic shear studies have shown that higher-order statistics (HOS) developed by independent teams now outperform standard two-point estimators in terms of statistical precision thanks to their sensitivity to the non-Gaussian features of large-scale structure. The aim of the Higher-Order Weak Lensing Statistics (HOWLS) project is to assess, compare, and combine the constraining power of ten different HOS on a common set of $Euclid$-like mocks, derived from N-body simulations. In this first paper of the HOWLS series, we computed the nontomographic ($\Omega_{\rm m}$, $\sigma_8$) Fisher information for the one-point probability distribution function, peak counts, Minkowski functionals, Betti numbers, persistent homology Betti numbers and heatmap, and scattering transform coefficients, and we compare them to the shear and convergence two-point correlation functions in the absence of any systematic bias. We also include forecasts for three implementations of higher-order moments, but these cannot be robustly interpreted as the Gaussian likelihood assumption breaks down for these statistics. Taken individually, we find that each HOS outperforms the two-point statistics by a factor of around two in the precision of the forecasts with some variations across statistics and cosmological parameters. When combining all the HOS, this increases to a $4.5$ times improvement, highlighting the immense potential of HOS for cosmic shear cosmological analyses with $Euclid$. The data used in this analysis are publicly released with the paper., Comment: 33 pages, 24 figures, main results in Fig. 19 & Table 5, version published in A&A
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- 2023
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161. Engineering Compounds for the Recovery of Critical Elements from Slags: Melt Characteristics of Li5AlO4, LiAlO2, and LiAl5O8
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Sven Hampel, Iyad Alabd Alhafez, Thomas Schirmer, Nina Merkert, Sophie Wunderlich, Alena Schnickmann, Haojie Li, Michael Fischlschweiger, and Ursula Elisabeth Adriane Fittschen
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Chemistry ,QD1-999 - Published
- 2024
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162. Archaeological and molecular evidence for ancient chickens in Central Asia
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Carli Peters, Kristine K. Richter, Shevan Wilkin, Sören Stark, Basira Mir-Makhamad, Ricardo Fernandes, Farhod Maksudov, Sirojidin Mirzaakhmedov, Husniddin Rahmonov, Stefanie Schirmer, Kseniia Ashastina, Alisher Begmatov, Michael Frachetti, Sharof Kurbanov, Michael Shenkar, Taylor Hermes, Fiona Kidd, Andrey Omelchenko, Barbara Huber, Nicole Boivin, Shujing Wang, Pavel Lurje, Madelynn von Baeyer, Rita Dal Martello, and Robert N. Spengler
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Science - Abstract
Abstract The origins and dispersal of the chicken across the ancient world remains one of the most enigmatic questions regarding Eurasian domesticated animals. The lack of agreement concerning timing and centers of origin is due to issues with morphological identifications, a lack of direct dating, and poor preservation of thin, brittle bird bones. Here we show that chickens were widely raised across southern Central Asia from the fourth century BC through medieval periods, likely dispersing along the ancient Silk Road. We present archaeological and molecular evidence for the raising of chickens for egg production, based on material from 12 different archaeological sites spanning a millennium and a half. These eggshells were recovered in high abundance at all of these sites, suggesting that chickens may have been an important part of the overall diet and that chickens may have lost seasonal egg-laying
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- 2024
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163. Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination
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Kapell, Hannah, Fazio, Luca, Dyckow, Julia, Schwarz, Sophia, Cruz-Herranz, Andrés, Mayer, Christina, Campos, Joaquin, D´Este, Elisa, Möbius, Wiebke, Cordano, Christian, Pröbstel, Anne-Katrin, Gharagozloo, Marjan, Zulji, Amel, Naik, Venu Narayanan, Delank, Anna-Katharina, Cerina, Manuela, Müntefering, Thomas, Lerma-Martin, Celia, Sonner, Jana K, Sin, Jung H, Disse, Paul, Rychlik, Nicole, Sabeur, Khalida, Chavali, Manideep, Srivastava, Rajneesh, Heidenreich, Matthias, Fitzgerald, Kathryn C, Seebohm, Guiscard, Stadelmann, Christine, Hemmer, Bernhard, Platten, Michael, Jentsch, Thomas J, Engelhardt, Maren, Budde, Thomas, Nave, Klaus-Armin, Calabresi, Peter A, Friese, Manuel A, Green, Ari J, Acuna, Claudio, Rowitch, David H, Meuth, Sven G, and Schirmer, Lucas
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Neurosciences ,Brain Disorders ,Multiple Sclerosis ,Autoimmune Disease ,Neurodegenerative ,1.1 Normal biological development and functioning ,Underpinning research ,Neurological ,Mice ,Animals ,Humans ,Ranvier's Nodes ,Potassium ,Neurons ,Oligodendroglia ,Encephalomyelitis ,Autoimmune ,Experimental ,Inflammation ,Multiple sclerosis ,Neurodegeneration ,Neuroscience ,Potassium channels ,Medical and Health Sciences ,Immunology - Abstract
Multiple sclerosis (MS) is a progressive inflammatory demyelinating disease of the CNS. Increasing evidence suggests that vulnerable neurons in MS exhibit fatal metabolic exhaustion over time, a phenomenon hypothesized to be caused by chronic hyperexcitability. Axonal Kv7 (outward-rectifying) and oligodendroglial Kir4.1 (inward-rectifying) potassium channels have important roles in regulating neuronal excitability at and around the nodes of Ranvier. Here, we studied the spatial and functional relationship between neuronal Kv7 and oligodendroglial Kir4.1 channels and assessed the transcriptional and functional signatures of cortical and retinal projection neurons under physiological and inflammatory demyelinating conditions. We found that both channels became dysregulated in MS and experimental autoimmune encephalomyelitis (EAE), with Kir4.1 channels being chronically downregulated and Kv7 channel subunits being transiently upregulated during inflammatory demyelination. Further, we observed that pharmacological Kv7 channel opening with retigabine reduced neuronal hyperexcitability in human and EAE neurons, improved clinical EAE signs, and rescued neuronal pathology in oligodendrocyte-Kir4.1-deficient (OL-Kir4.1-deficient) mice. In summary, our findings indicate that neuron-OL compensatory interactions promoted resilience through Kv7 and Kir4.1 channels and identify pharmacological activation of nodal Kv7 channels as a neuroprotective strategy against inflammatory demyelination.
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- 2023
164. Fleischwissen: Zur Verdinglichung des Lebendigen in globalisierten Märkten
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Gunther Hirschfelder, Lars Winterberg, René John, Jana Rückert-John, Corinna Schirmer, Gunther Hirschfelder, Lars Winterberg, René John, Jana Rückert-John, Corinna Schirmer and Gunther Hirschfelder, Lars Winterberg, René John, Jana Rückert-John, Corinna Schirmer, Gunther Hirschfelder, Lars Winterberg, René John, Jana Rückert-John, Corinna Schirmer
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- 2024
165. Tops und Flops, Mythen und Hypes im automobilen Marketing
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Schirmer, Armin, primary
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- 2024
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166. Big Data: Vom Datenmüll zum Datengold, oder umgekehrt?
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Schirmer, Armin, primary
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- 2024
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167. Holistic Assembly Planning Framework for Dynamic Human-Robot Collaboration
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Schirmer, Fabian, primary, Kranz, Philipp, additional, Rose, Chad G., additional, Schmitt, Jan, additional, and Kaupp, Tobias, additional
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- 2024
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168. Bevölkerungsschutzrecht post corona – nach der Katastrophe ist vor der Katastrophe?
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Schirmer, Jakob, primary
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- 2024
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169. Powerful yet lonely: Is 3C 297 a high-redshift fossil group?
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Missaglia, Valentina, Madrid, Juan P., Schirmer, Mischa, Massaro, Francesco, Rodriguez-Ardila, Alberto, Donzelli, Carlos J., Valencia, Martell, Paggi, Alessandro, Kraft, Ralph P., Stuardi, Chiara, and Wilkes, Belinda J.
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Astrophysics - Astrophysics of Galaxies - Abstract
The environment of the high-redshift (z=1.408), powerful radio-loud galaxy 3C 297 has several distinctive features of a galaxy cluster. Among them, a characteristic halo of hot gas revealed by Chandra X-ray observations. In addition, a radio map obtained with the Very Large Array (VLA) shows a bright hotspot in the northwestern direction, created by the interaction of the AGN jet arising from 3C 297 with its environment. In the X-ray images, emission cospatial with the northwestern radio lobe is detected, and peaks at the position of the radio hotspot. The extended, complex X-ray emission observed with our new Chandra data is largely unrelated to its radio structure. Despite having attributes of a galaxy cluster, no companion galaxies have been identified from 39 new spectra of neighboring targets of 3C 297 obtained with the Gemini Multi-Object Spectrograph. None of the 19 galaxies for which a redshift was determined lies at the same distance as 3C 297. The optical spectral analysis of the new Gemini spectrum of 3C 297 reveals an isolated Type-II radio-loud AGN. We also detected line broadening in [O II](3728) with a FWHM about 1700 km/s and possible line shifts of up to 500-600 km/s. We postulate that the host galaxy of 3C 297 is a fossil group, in which most of the stellar mass has merged into a single object, leaving behind an X-ray halo., Comment: The Astrophysical Journal Supplement Series, in press
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- 2022
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170. Topological superconductivity induced by spin-orbit coupling, perpendicular magnetic field and superlattice potential
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Schirmer, Jonathan, Jain, J. K., and Liu, C. -X.
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Condensed Matter - Superconductivity ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Strongly Correlated Electrons - Abstract
Topological superconductors support Majorana modes, which are quasiparticles that are their own antiparticles and which obey non-Abelian statistics in which successive exchanges of particles do not always commute. Here we investigate whether a two-dimensional superconductor with ordinary s-wave pairing can be rendered topological by the application of a strong magnetic field. To address this, we obtain the self-consistent solutions to the mean field Bogoliubov-de Gennes equations, which are a large set of nonlinearly coupled equations, for electrons moving on a lattice. We find that the topological "quantum Hall superconductivity" is facilitated by a combination of spin-orbit coupling, which locks an electron's spin to its momentum as it moves through a material, and a coupling to an external periodic potential which gives a dispersion to the Landau levels and also distorts the Abrikosov lattice. We find that, for a range of parameters, the Landau levels broadened by the external periodic potential support topological superconductivity, which is typically accompanied by a lattice of "giant" $h/e$ vortices as opposed to the familiar lattice of $h/2e$ Abrikosov vortices. In the presence of a periodic potential, we find it necessary to use an ansatz for the pairing potential of the form $\Delta(\vec{r})e^{i2\vec{Q}\cdot\vec{r}}$ where $\Delta(\vec{r})$ has a periodicity commensurate with the periodic potential. However, despite this form of the pairing potential, the current in the ground state is zero. In the region of ordinary superconductivity, we typically find a lattice of dimers of $h/2e$ vortices. Our work suggests a realistic proposal for achieving topological superconductivity, as well as a helical order parameter and unusual Abrikosov lattices., Comment: 19 + 9 pages
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- 2022
171. Euclid preparation. XXVII. Covariance model validation for the 2-point correlation function of galaxy clusters
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Euclid Collaboration, Fumagalli, A., Saro, A., Borgani, S., Castro, T., Costanzi, M., Monaco, P., Munari, E., Sefusatti, E., Aghanim, N., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Dubath, F., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Franzetti, P., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hornstrup, A., Hudelot, P., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Mei, S., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Raison, F., Rebolo-Lopez, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Fabbian, G., Farina, M., Lindholm, V., Maino, D., Mauri, N., Neissner, C., Scottez, V., Zucca, E., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Blanchard, A., Borlaff, A. S, Burigana, C., Cabanac, R., Carvalho, C. S., Casas, S., Castignani, G., Chambers, K., Cooray, A. R., Coupon, J., Courtois, H. M., Davini, S., de la Torre, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Ferreira, P. G., Finelli, F., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Muňoz, A. Jimenez, Joachimi, B., Kansal, V., Keihänen, E., Kirkpatrick, C. C., Loureiro, A., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Pollack, J. E., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schirmer, M., Sereno, M., Mancini, A. Spurio, Stadel, J., Steinwagner, J., Valieri, C., Valiviita, J., Veropalumbo, A., and Viel, M.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,85A40 - Abstract
Aims. We validate a semi-analytical model for the covariance of real-space 2-point correlation function of galaxy clusters. Methods. Using 1000 PINOCCHIO light cones mimicking the expected Euclid sample of galaxy clusters, we calibrate a simple model to accurately describe the clustering covariance. Then, we use such a model to quantify the likelihood analysis response to variations of the covariance, and investigate the impact of a cosmology-dependent matrix at the level of statistics expected for the Euclid survey of galaxy clusters. Results. We find that a Gaussian model with Poissonian shot-noise does not correctly predict the covariance of the 2-point correlation function of galaxy clusters. By introducing few additional parameters fitted from simulations, the proposed model reproduces the numerical covariance with 10 per cent accuracy, with differences of about 5 per cent on the figure of merit of the cosmological parameters $\Omega_{\rm m}$ and $\sigma_8$. Also, we find that the cosmology-dependence of the covariance adds valuable information that is not contained in the mean value, significantly improving the constraining power of cluster clustering. Finally, we find that the cosmological figure of merit can be further improved by taking mass binning into account. Our results have significant implications for the derivation of cosmological constraints from the 2-point clustering statistics of the Euclid survey of galaxy clusters., Comment: 18 pages, 14 figures
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- 2022
172. Time Domain Sensitivity of the Tracking Error
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O'Neil, S., Schirmer, S. G., Langbein, F. C., Weidner, C. A., and Jonckheere, E.
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Quantum Physics ,Electrical Engineering and Systems Science - Systems and Control - Abstract
A strictly time-domain formulation of the log-sensitivity of the error signal to structured plant uncertainty is presented and analyzed through simple but representative classical and quantum systems. Results demonstrate that across a wide range of physical systems, maximization of performance (minimization of the error signal) asymptotically or at a specific time comes at the cost of increased log-sensitivity, implying a time-domain constraint analogous to the frequency-domain identity $\mathbf{S(s) + T(s) = I}$. While of limited value in classical problems based on asymptotic stabilization or tracking, such a time-domain formulation is valuable in assessing the reduced robustness cost concomitant with high-fidelity quantum control schemes predicated on time-based performance measures., Comment: 12 pages, 10 figures, 1 table. in IEEE Transactions on Automatic Control. Scheduled for publication Feb 2024
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- 2022
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173. Euclid Near Infrared Spectrometer and Photometer instrument flight model presentation, performance and ground calibration results summary
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Maciaszek, T., Ealet, A., Gillard, W., Jahnke, K., Barbier, R., Prieto, E., Bon, W., Bonnefoi, A., Caillat, A., Carle, M., Costille, A., Ducret, F., Fabron, C., Foulon, B., Gimenez, J. L., Grassi, E., Jaquet, M., Mignant, D. Le, Martin, L., Pamplona, T., Sanchez, P., Clémens, J. C., Caillat, L., Niclas, M., Secroun, A., Kubik, B., Ferriol, S., Berthe, M., Barrière, J. C., Fontigne, J., Valenziano, L., Auricchio, N., Battaglia, P., De Rosa, A., Farinelli, R., Franceschi, E., Medinaceli, E., Morgante, G., Sortino, F., Trifoglio, M., Corcione, L., Capobianco, V., Ligori, S., Dusini, S., Borsato, E., Corso, F. Dal, Laudisio, F., Sirignano, C., Stanco, L., Ventura, S., Patrizii, L., Chiarusi, T., Fornari, F., Giacomini, F., Margiotta, A., Mauri, N., Pasqualini, L., Sirri, G., Spurio, M., Tenti, M., Travaglini, R., Bonoli, C., Bortoletto, F., Balestra, A., D'Alessandro, M., Grupp, F., Penka, D., Steinwagner, J., Hormuth, F., Schirmer, M., Seidel, G., Padilla, C., Casas, R., Lloro, I., Toledo-Moreo, R., Gomez, J., Colodro-Conde, C., Lizán, D., Diaz, J. J., Lilje, P. B., Andersen, M. I., Andersen, J., Sørensen, A., Hornstrup, A., Jessen, N. C., Thizy, C., Holmes, W., Pniel, M., Jhabvala, M., Pravdo, S., Seiffert, M., Waczynski, A., Laureijs, R. J., Racca, G., Salvignol, J. C., Boenke, T., Strada, P., and Mellier, Y.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The NISP (Near Infrared Spectrometer and Photometer) is one of the two Euclid instruments. It operates in the near-IR spectral region (950-2020nm) as a photometer and spectrometer. The instrument is composed of: a cold (135 K) optomechanical subsystem consisting of a Silicon carbide structure, an optical assembly, a filter wheel mechanism, a grism wheel mechanism, a calibration unit, and a thermal control system, a detection system based on a mosaic of 16 H2RG with their front-end readout electronic, and a warm electronic system (290 K) composed of a data processing / detector control unit and of an instrument control unit that interfaces with the spacecraft via a 1553 bus for command and control and via Spacewire links for science data. This paper presents: the final architecture of the flight model instrument and subsystems, and the performance and the ground calibration measurement done at NISP level and at Euclid Payload Module level at operational cold temperature., Comment: 18 pages, to appear in Proceedings of the SPIE
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- 2022
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174. Superconductivity in a system of interacting spinful semions
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Kudo, Koji and Schirmer, Jonathan
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Condensed Matter - Superconductivity ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Strongly Correlated Electrons - Abstract
Non-interacting particles obeying certain fractional statistics have been predicted to exhibit superconductivity. We discuss the issue in an attractively interacting system of spinful semions on a lattice by numerically investigating the presence of off-diagonal long-range order at zero temperature. For this purpose, we construct a Hubbard model wherein two semions with opposite spin can virtually coincide while maintaining consistency with the fractional braiding statistics. Clear off-diagonal long range order is seen in the strong coupling limit, consistent with the expectation that a pair of semions obeys Bose statistics. We find that the semion system behaves similarly to a system of fermions with the same attractive Hubbard $U$ interaction for a wide range of $U$, suggesting that semions also undergo a BCS to BEC crossover as a function of $U$., Comment: 11 pages, 10 figures
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- 2022
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175. The association between preoperative epidural steroid injections and postoperative cervical and lumbar surgical site infections: A systematic review and meta-analysis
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David Sherwood, DO, Jakob Dovgan, MD, Derek Schirmer, DO, R. Sterling Haring, DO, MPH, and Byron Schneider, MD
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Spine ,Infection ,Epidural ,Steroid ,Spinal stenosis ,Surgery ,Orthopedic surgery ,RD701-811 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
ABSTRACT: Background: Is there a statistically significant association between preoperative epidural steroid injections (ESI) and postoperative cervical and lumbar spinal surgery infections (SSI)? Methods: A systematic review and meta-analysis was completed of patients 18 years or older who underwent elective cervical or lumbar spinal surgery. Those who underwent surgery with preoperative ESI were compared to those without. We assessed for differences in postoperative SSI incidence. Electronic literature databases were searched through October 2022. Peer-reviewed publications that included raw data regarding epidural exposure and non-exposure were included. Case reports, case series, abstracts, editorials, or publications that did not include raw data were excluded. Odd's ratios (OR) were calculated from the raw data collected. Meta-analysis was done using RevMan v5 with a fixed effects model. Results: We identified 16 articles for inclusion. When not controlling for the type of surgery and time from ESI to surgery, there was a statistically significant OR between preoperative ESI and postoperative SSI. The association persisted when the ESI was performed within 30 days or 31-90 days of the surgery. No association was discovered when evaluating only cervical spine surgeries. The evidence is assigned a “moderate” GRADE rating. Conclusions: Our analysis shows a small, time-dependent, statistically significant association between preoperative ESI and postoperative lumbar SSI may exist. However, the OR produced, while statistically significant, are close enough to 1.0 that clinically, the effect size is “small.” The number needed to treat for an ESI in the appropriate clinical setting is, at worst, 3. The number needed to harm, meaning the number of patients who undergo an ESI at any time before their spine surgery and then develop a SSI, is 111 patients. Ultimately, the surgical sparing potential from an ESI outweighs the SSI risk based on our findings.
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- 2024
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176. Multimodal treatment according to the NPC‐GPOH trials in adult patients with nasopharyngeal cancer—Analysis based on a single‐center experience
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Martin Leu, Hanibal Bohnenberger, Manuel Guhlich, Markus Anton Schirmer, Yiannis Pilavakis, Hendrik Andreas Wolff, Stefan Rieken, and Leif Hendrik Dröge
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antiviral treatment ,interferon‐β ,nasopharyngeal cancer ,NPC‐GPOH trials ,radiochemotherapy ,WHO histological type ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background and Aim The German NPC‐GPOH trials introduced treatment including neoadjuvant chemotherapy, radiochemotherapy (RCT) and antiviral treatment in patients aged 25 years or younger with nasopharyngeal cancer (NPC). We conducted a retrospective study on outcomes of patients at the age of ≥26 years treated accordingly at our institution. Methods Consecutive patients who received primary RCT for NPC were included. The Kaplan–Meier method was used to calculate survival probabilities, and the Cox regression analysis was used to test for an influence of the variables on outcomes. Acute and late toxicity were evaluated via CTCAE criteria and LENT/SOMA criteria, respectively. Results In total, 30 patients were included. Diagnosis was made from 09/1994 to 11/2016. The median 5 year overall survival (OS), disease‐free survival (DFS), cancer‐specific survival (CSS) and locoregional recurrence‐free survival (LRC) were 75%, 56%, 83%, and 85%, respectively. We found a negative impact on outcomes (p
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- 2024
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177. Fusarioid fungi in soils of agroecological polycultures and tropical dry forest in rural Triunfo, Brazil: Insights into sustainable agricultural management
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Amanda Lucia Alves, Thiago Vitor da Silva, Jorge Luiz Schirmer de Mattos, Ana Carla da Silva Santos, Roger Fagner Ribeiro Melo, and Patricia Vieira Tiago
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Agroforestry ,Family farming ,Intensive Agriculture ,Soil quality indicators ,Trophobiosis. ,Botany ,QK1-989 - Abstract
Abstract This study aimed to identify fusarioid fungi in the soils of sustainably managed agricultural areas and a fragment of the Brazilian Caatinga, both in a semi-arid region of Brazil. We provide a survey of peer-reviewed papers reporting the substrates, hosts, and geographic regions in Brazil in which the identified species were of agricultural interest. Soil samples were collected in July 2019, February 2020, and July 2020 from different agroecosystems and a fragment of the Brazilian Caatinga in rural Triunfo, Brazil. Fusarioid fungi were obtained by serial dilution of soil and colony purification using single-conidial culturing. Maximum likelihood evaluation (ML) based on sequences from the tef1-α gene was used to identify fusarioid fungi. The distribution of these species in other agroecosystems and the natural environment in Brazil was assessed by an extensive search of the literature available in public databases. Fusarium annulatum, F. verticillioides, F. lacertarum, and Neocosmospora vasinfecta were identified. These species are distributed throughout Brazil and are registered as plant pathogens, mainly in areas with conventional agriculture. These data reinforce the importance of sustainable soil management in agricultural areas and expand our knowledge of the behavior of these microorganisms in environments without human interference.
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- 2024
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178. What do patients with heart failure disclose about medication adherence at home to their hospital and primary care doctors? Exploratory interaction-based observational cohort study
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Henrik Schirmer, Torbjørn Wisløff, Pål Gulbrandsen, Julia Menichetti, Christine Frigaard, Herman Bjørnstad, Tone Breines Simonsen, and Jennifer Gerwing
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Medicine - Abstract
Objectives The main objective of this study was twofold: to investigate what kind of information patients with heart failure (HF) tell their doctors about their medication adherence at home, and how often such information is provided in consultations where medication reconciliation is recommended. To meet these objectives, we developed an analysis to recognise, define, and count (1) patient utterances including medication adherence disclosures in clinical interactions (MADICI), (2) MADICI including red-flags for non-adherence, and (3) MADICI initiated by patients without prompts from their doctor.Design Exploratory interaction-based observational cohort study. Inductive microanalysis of authentic patient–doctor consultations, audio-recorded at three time-points for each patient: (1) first ward visit in hospital, (2) discharge visit from hospital, and (3) follow-up visit with general practitioner (GP).Setting Norway (2022–2023).Participants 25 patients with HF (+65 years) and their attending doctors (23 hospital doctors, 25 GPs).Results We recognised MADICI by two criteria: (1) they are about medication prescribed for use at home, AND (2) they involve patients’ action, experience, or stance regarding medications. Using these criteria, we identified 427 MADICIs in 25 patient trajectories: 143 (34%) at first ward visit (min–max=0–35, median=3), 57 (13%) at discharge visit (min–max=0–8, median=2), 227 (53%) at GP-visit (min–max=2–24, median=7). Of 427 MADICIs, 235 (55%) included red-flags for non-adherence. Bumetanide and atorvastatin were most frequently mentioned as problematic. Patients initiated 146 (34%) of 427 MADICIs. Of 235 ‘red-flag MADICIs’, 101 (43%) were initiated by patients.Conclusions Self-managing older patients with HF disclosed information about their use of medications at home, often including red-flags for non-adherence. Patients who disclosed information that signals adherence problems tended to do so unprompted. Such disclosures generate opportunities for doctors to assess and support patients’ medication adherence at home.
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- 2024
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179. Quality of life in patients with statin intolerance: a multicentre prospective registry studyResearch in context
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Paulina E. Stürzebecher, Ioanna Gouni-Berthold, Christina Mateev, Ole Frenzel, Stephan Erbe, Jes-Niels Boeckel, Markus Scholz, Ulrike Schatz, Oliver Weingärtner, Ursula Kassner, Ulrich Laufs, A. Baessler, K. Borucki, G. Heine, G. Hoh, R. Klingenberg, W. Koenig, K. Parhofer, V. Rettig-Ewen, V. Schettler, S. Schirmer, S. Seiler-Mußler, K. Stach-Jablonski, J. Taggeselle, A. Tamm, and A. Vogt
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Statin ,Intolerance ,Muscle ,Symptoms ,Pain ,Women ,Public aspects of medicine ,RA1-1270 - Abstract
Summary: Background: Statin intolerance is associated with increased cardiovascular risk. Symptoms and patients’ characteristics are incompletely known. We aimed to analyse the health-related quality of life (QOL) associated with statin intolerance. Methods: The Statin Intolerance Registry (SIR) is an observational, prospective, multicentre study that included 1111 patients, with intolerance to at least two different statins, between 2021 and 2023 in Germany. SIR baseline data were compared to individuals with and without statin therapy of the population-based LIFE-Adult Study (n = 9983). Findings: The mean age in SIR was 66.1 years (standard deviation (SD) 9.9). The cohort was characterized by a higher proportion of women compared to patients on statins in LIFE-Adult (57.7% vs. 38.2%). SIR patients had impaired QOL (mean EQ VAS score of 64.9 (SD 18.1)) as measured by EuroQol (EQ-5D-5L)), which further deteriorated with age. Muscle symptoms were frequent (95.8%) and were associated with severe pain in 43.2% and intake of pain medication in 32.3% of statin intolerant patients. 10.3% had a diagnosis of depression. Women reported more pronounced symptoms than men. A data-driven k-means analysis, based on variables predicting severity of pain while on statin therapy, identified five clusters of SIR patients. The clusters differed in sex, prevalence of depression, QOL, comorbidities, and expectations to tolerate statin therapy. Interpretation: Statin intolerance is associated with impaired QOL. Women are more frequently and severely affected. The identified clusters may help to identify patients at risk and to develop individualized strategies to improve patient trajectories and outcomes. Funding: Leipzig University, research grants from Daiichi Sankyo, Novartis, and Amgen to Leipzig University.
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- 2024
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180. Investigating the increase of violent speech in Incel communities with human-guided GPT-4 prompt iteration
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Daniel Matter, Miriam Schirmer, Nir Grinberg, and Jürgen Pfeffer
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GPT-4 ,violent language ,Incels ,annotator agreement ,time analysis ,Psychology ,BF1-990 - Abstract
This study investigates the prevalence of violent language on incels.is. It evaluates GPT models (GPT-3.5 and GPT-4) for content analysis in social sciences, focusing on the impact of varying prompts and batch sizes on coding quality for the detection of violent speech. We scraped over 6.9M posts from incels.is and categorized a random sample into non-violent, explicitly violent, and implicitly violent content. Two human coders annotated 3, 028 posts, which we used to tune and evaluate GPT-3.5 and GPT-4 models across different prompts and batch sizes regarding coding reliability. The best-performing GPT-4 model annotated an additional 45, 611 posts for further analysis. We find that 21.91% of the posts on the forum contain some form of violent language. Within the overall forum, 18.12% of posts include explicit violence, while 3.79% feature implicit violence. Our results show a significant rise in violent speech on incels.is, both at the community and individual level. This trend is particularly pronounced among users with an active posting behavior that lasts for several hours up to one month. While the use of targeted violent language decreases, general violent language increases. Additionally, mentions of self-harm decline, especially for users who have been active on the site for over 2.5 years. We find substantial agreement between both human coders (κ = 0.65), while the best GPT-4 model yields good agreement with both human coders (κ = 0.54 for Human A and κ = 0.62 for Human B). Overall, this research offers effective ways to pinpoint violent language on a large scale, helping with content moderation and facilitating further research into causal mechanisms and potential mitigations of violent expression and online radicalization in communities like incels.is.
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- 2024
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181. KoPro - Configurable Process Chains for Human-Robot Collaborative Assembly.
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Philipp Kranz, Fabian Schirmer, Adrian Müller 0001, Usama Ali, Jan Schmitt, and Tobias Kaupp
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- 2024
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182. Sensitivity Bounds for Quantum Control and Time-Domain Performance Guarantees.
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Sean O'Neil, Edmond A. Jonckheere, and Sophie G. Schirmer
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- 2024
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183. Time-Domain Sensitivity of the Tracking Error.
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Sean O'Neil, Sophie G. Schirmer, Frank C. Langbein, Carrie Ann Weidner, and Edmond A. Jonckheere
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- 2024
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184. Prospective study on embolization of intracranial aneurysms with the pipeline device (PREMIER study): 3-year results with the application of a flow diverter specific occlusion classification
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Hanel, Ricardo A, Cortez, Gustavo M, Lopes, Demetrius Klee, Nelson, Peter Kim, Siddiqui, Adnan H, Jabbour, Pascal, Pereira, Vitor Mendes, István, Istvan Szikora, Zaidat, Osama O, Bettegowda, Chetan, Colby, Geoffrey P, Mokin, Maxim, Schirmer, Clemens M, Hellinger, Frank R, Given, Curtis, Krings, Timo, Taussky, Philipp, Toth, Gabor, Fraser, Justin F, Chen, Michael, Priest, Ryan, Kan, Peter, Fiorella, David, Frei, Donald, Aagaard-Kienitz, Beverly, Diaz, Orlando, Malek, Adel M, Cawley, C Michael, Puri, Ajit S, and Kallmes, David F
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Biomedical and Clinical Sciences ,Clinical Sciences ,Hematology ,Clinical Research ,Stroke ,Neurosciences ,Clinical Trials and Supportive Activities ,Humans ,Cerebral Angiography ,Embolization ,Therapeutic ,Follow-Up Studies ,Intracranial Aneurysm ,Prospective Studies ,Retrospective Studies ,Treatment Outcome ,aneurysm ,flow diverter ,intervention ,Clinical sciences - Abstract
BackgroundThe pipeline embolization device (PED; Medtronic) has presented as a safe and efficacious treatment for small- and medium-sized intracranial aneurysms. Independently adjudicated long-term results of the device in treating these lesions are still indeterminate. We present 3-year results, with additional application of a flow diverter specific occlusion scale.MethodsPREMIER (prospective study on embolization of intracranial aneurysms with pipeline embolization device) is a prospective, single-arm trial. Inclusion criteria were patients with unruptured wide-necked intracranial aneurysms ≤12 mm. Primary effectiveness (complete aneurysm occlusion) and safety (major neurologic event) endpoints were independently monitored and adjudicated.ResultsAs per the protocol, of 141 patients treated with a PED, 25 (17.7%) required angiographic follow-up after the first year due to incomplete aneurysm occlusion. According to the Core Radiology Laboratory review, three (12%) of these patients progressed to complete occlusion, with an overall rate of complete aneurysm occlusion at 3 years of 83.3% (115/138). Further angiographic evaluation using the modified Cekirge-Saatci classification demonstrated that complete occlusion, neck residual, or aneurysm size reduction occurred in 97.1%. The overall combined safety endpoint at 3 years was 2.8% (4/141), with only one non-debilitating major event occurring after the first year. There was one case of aneurysm recurrence but no cases of delayed rupture in this series.ConclusionsThe PED device presents as a safe and effective modality in treating small- and medium-sized intracranial aneurysms. The application of a flow diverter specific occlusion classification attested the long-term durability with higher rate of successful aneurysm occlusion and no documented aneurysm rupture.Trial registrationNCT02186561.
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- 2023
185. Euclid preparation: XXII. Selection of Quiescent Galaxies from Mock Photometry using Machine Learning
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Euclid Collaboration, Humphrey, A., Bisigello, L., Cunha, P. A. C., Bolzonella, M., Fotopoulou, S., Caputi, K., Tortora, C., Zamorani, G., Papaderos, P., Vergani, D., Brinchmann, J., Moresco, M., Amara, A., Auricchio, N., Baldi, M., Bender, R., Bonino, D., Branchini, E., Brescia, M., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Fumana, M., Gomez-Alvarez, P., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Holmes, W., Hormuth, F., Jahnke, K., Kummel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kohley, R., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., McCracken, H. J., Medinaceli, E., Melchior, M., Meneghetti, M., Merlin, E., Meylan, G., Moscardini, L., Munari, E., Nakajima, R., Niemi, S. M., Nightingale, J., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Scaramella, R., Schneider, P., Scodeggio, M., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespi, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zoubian, J., Andreon, S., Bardelli, S., Boucaud, A., Farinelli, R., Gracia-Carpio, J., Maino, D., Mauri, N., Mei, S., Morisset, N., Sureau, F., Tenti, M., Tramacere, A., Zucca, E., Baccigalupi, C., Balaguera-Antolinez, A., Biviano, A., Blanchard, A., Borgani, S., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Colodro-Conde, C., Cooray, A. R., Coupon, J., Courtois, H. M., Cucciati, O., Davini, S., De Lucia, G., Dole, H., Escartin, J. A., Escoffier, S., Fabricius, M., Farina, M., Finelli, F., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hook, I., Huertas-Company, M., Joachimi, B., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Lindholm, V., Mainetti, G., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Maturi, M., Metcalf, R. B., Morgante, G., Nucita, A. A., Patrizii, L., Peel, A., Pollack, J. E., Popa, V., Porciani, C., Potter, D., Reimberg, P., Sanchez, A. G., Schirmer, M., Schultheis, M., Scottez, V., Sefusatti, E., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Viel, M., Calura, F., and Hildebrandt, H.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
The Euclid Space Telescope will provide deep imaging at optical and near-infrared wavelengths, along with slitless near-infrared spectroscopy, across ~15,000 sq deg of the sky. Euclid is expected to detect ~12 billion astronomical sources, facilitating new insights into cosmology, galaxy evolution, and various other topics. To optimally exploit the expected very large data set, there is the need to develop appropriate methods and software. Here we present a novel machine-learning based methodology for selection of quiescent galaxies using broad-band Euclid I_E, Y_E, J_E, H_E photometry, in combination with multiwavelength photometry from other surveys. The ARIADNE pipeline uses meta-learning to fuse decision-tree ensembles, nearest-neighbours, and deep-learning methods into a single classifier that yields significantly higher accuracy than any of the individual learning methods separately. The pipeline has `sparsity-awareness', so that missing photometry values are still informative for the classification. Our pipeline derives photometric redshifts for galaxies selected as quiescent, aided by the `pseudo-labelling' semi-supervised method. After application of the outlier filter, our pipeline achieves a normalized mean absolute deviation of ~< 0.03 and a fraction of catastrophic outliers of ~< 0.02 when measured against the COSMOS2015 photometric redshifts. We apply our classification pipeline to mock galaxy photometry catalogues corresponding to three main scenarios: (i) Euclid Deep Survey with ancillary ugriz, WISE, and radio data; (ii) Euclid Wide Survey with ancillary ugriz, WISE, and radio data; (iii) Euclid Wide Survey only. Our classification pipeline outperforms UVJ selection, in addition to the Euclid I_E-Y_E, J_E-H_E and u-I_E,I_E-J_E colour-colour methods, with improvements in completeness and the F1-score of up to a factor of 2. (Abridged), Comment: 37 pages (including appendices), 26 figures; accepted for publication in Astronomy & Astrophysics
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- 2022
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186. Euclid preparation XXVI. The Euclid Morphology Challenge. Towards structural parameters for billions of galaxies
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Euclid Collaboration, Bretonnière, H., Kuchner, U., Huertas-Company, M., Merlin, E., Castellano, M., Tuccillo, D., Buitrago, F., Conselice, C. J., Boucaud, A., Häußler, B., Kümmel, M., Hartley, W. G., Ayllon, A. Alvarez, Bertin, E., Ferrari, F., Ferreira, L., Gavazzi, R., Hernández-Lang, D., Lucatelli, G., Robotham, A. S. G., Schefer, M., Wang, L., Cabanac, R., Sánchez, H. Domínguez, Duc, P. -A., Fotopoulou, S., Kruk, S., La Marca, A., Margalef-Bentabol, B., Marleau, F. R., Tortora, C., Aghanim, N., Amara, A., Auricchio, N., Azzollini, R., Baldi, M., Bender, R., Bodendorf, C., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Dinis, J., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kohley, R., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., McCracken, H. J., Medinaceli, E., Melchior, M., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W., Pettorino, V., Polenta, G., Poncet, M., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rosset, C., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Skottfelt, J., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Lindholm, V., Mauri, N., Mei, S., Scottez, V., Zucca, E., Baccigalupi, C., Ballardini, M., Bernardeau, F., Biviano, A., Borgani, S., Borlaff, A. S., Burigana, C., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A. R., Coupon, J., Courtois, H. M., Davini, S., De Lucia, G., Desprez, G., Escartin, J. A., Escoffier, S., Fabricius, M., Farina, M., Fontana, A., Ganga, K., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Ilić, S., Joachimi, B., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Maturi, M., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valiviita, J., van Mierlo, S. E., Veropalumbo, A., Viel, M., Weaver, J. R., and Scott, D.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The various Euclid imaging surveys will become a reference for studies of galaxy morphology by delivering imaging over an unprecedented area of 15 000 square degrees with high spatial resolution. In order to understand the capabilities of measuring morphologies from Euclid-detected galaxies and to help implement measurements in the pipeline, we have conducted the Euclid Morphology Challenge, which we present in two papers. While the companion paper by Merlin et al. focuses on the analysis of photometry, this paper assesses the accuracy of the parametric galaxy morphology measurements in imaging predicted from within the Euclid Wide Survey. We evaluate the performance of five state-of-the-art surface-brightness-fitting codes DeepLeGATo, Galapagos-2, Morfometryka, Profit and SourceXtractor++ on a sample of about 1.5 million simulated galaxies resembling reduced observations with the Euclid VIS and NIR instruments. The simulations include analytic S\'ersic profiles with one and two components, as well as more realistic galaxies generated with neural networks. We find that, despite some code-specific differences, all methods tend to achieve reliable structural measurements (10% scatter on ideal S\'ersic simulations) down to an apparent magnitude of about 23 in one component and 21 in two components, which correspond to a signal-to-noise ratio of approximately 1 and 5 respectively. We also show that when tested on non-analytic profiles, the results are typically degraded by a factor of 3, driven by systematics. We conclude that the Euclid official Data Releases will deliver robust structural parameters for at least 400 million galaxies in the Euclid Wide Survey by the end of the mission. We find that a key factor for explaining the different behaviour of the codes at the faint end is the set of adopted priors for the various structural parameters., Comment: Accepted by A&A. 30 pages, 23+6 figures, Euclid pre-launch key paper. Companion paper: Euclid Collaboration XXV: Merlin et al. 2022 Minor corrections after journal review
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- 2022
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187. Euclid preparation. XXV. The Euclid Morphology Challenge -- Towards model-fitting photometry for billions of galaxies
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Euclid Collaboration, Merlin, E., Castellano, M., Bretonnière, H., Huertas-Company, M., Kuchner, U., Tuccillo, D., Buitrago, F., Peterson, J. R., Conselice, C. J., Caro, F., Dimauro, P., Nemani, L., Fontana, A., Kümmel, M., Häußler, B., Hartley, W. G., Ayllon, A. Alvarez, Bertin, E., Dubath, P., Ferrari, F., Ferreira, L., Gavazzi, R., Hernández-Lang, D., Lucatelli, G., Robotham, A. S. G., Schefer, M., Tortora, C., Aghanim, N., Amara, A., Amendola, L., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Branchini, E., Brescia, M., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Dinis, J., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Franzetti, P., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kitching, T., Kohley, R., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., McCracken, H. J, Medinaceli, E., Melchior, M., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Polenta, G., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Skottfelt, J., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Tutusaus, I., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Boucaud, A., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Lindholm, V., Mauri, N., Mei, S., Neissner, C., Scottez, V., Tramacere, A., Zucca, E., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Borgani, S., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A. R., Coupon, J., Courtois, H. M., Cucciati, O., Davini, S., De Lucia, G., Desprez, G., Escartin, J. A., Escoffier, S., Farina, M., Ganga, K., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Ilic, S., Joachimi, B., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maturi, M., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., van Mierlo, S. E., Veropalumbo, A., Viel, M., Weaver, J. R., and Scott, D.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ESA Euclid mission will provide high-quality imaging for about 1.5 billion galaxies. A software pipeline to automatically process and analyse such a huge amount of data in real time is being developed by the Science Ground Segment of the Euclid Consortium; this pipeline will include a model-fitting algorithm, which will provide photometric and morphological estimates of paramount importance for the core science goals of the mission and for legacy science. The Euclid Morphology Challenge is a comparative investigation of the performance of five model-fitting software packages on simulated Euclid data, aimed at providing the baseline to identify the best suited algorithm to be implemented in the pipeline. In this paper we describe the simulated data set, and we discuss the photometry results. A companion paper (Euclid Collaboration: Bretonni\`ere et al. 2022) is focused on the structural and morphological estimates. We created mock Euclid images simulating five fields of view of 0.48 deg2 each in the $I_E$ band of the VIS instrument, each with three realisations of galaxy profiles (single and double S\'ersic, and 'realistic' profiles obtained with a neural network); for one of the fields in the double S\'ersic realisation, we also simulated images for the three near-infrared $Y_E$, $J_E$ and $H_E$ bands of the NISP-P instrument, and five Rubin/LSST optical complementary bands ($u$, $g$, $r$, $i$, and $z$). To analyse the results we created diagnostic plots and defined ad-hoc metrics. Five model-fitting software packages (DeepLeGATo, Galapagos-2, Morfometryka, ProFit, and SourceXtractor++) were compared, all typically providing good results. (cut), Comment: 29 pages, 33 figures. Euclid pre-launch key paper. Companion paper: Bretonniere et al. 2022
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- 2022
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188. Nano-grain depletion in photon-dominated regions
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Schirmer, T., Ysard, N., Habart, E., Jones, A. P., Abergel, A., and Verstraete, L.
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Astrophysics - Astrophysics of Galaxies - Abstract
Context. Carbonaceous nano-grains play a fundamental role in the physico-chemistry of the interstellar medium (ISM) and especially of photon-dominated regions (PDRs). Their properties vary with the local physical conditions and affect the local chemistry and dynamics. Aims. We aim to highlight the evolution of carbonaceous nano-grains in three different PDRs and propose a scenario of dust evolution as a response to the physical conditions. Methods. We used Spitzer/IRAC (3.6, 4.5, 5.8, and 8 $\mu$m) and Spitzer/MIPS (24 $\mu$m) together with Herschel/PACS (70 $\mu$m) to map dust emission in IC63 and the Orion Bar. To assess the dust properties, we modelled the dust emission in these regions using the radiative transfer code SOC together with the THEMIS dust model. Results. Regardless of the PDR, we find that nano-grains are depleted and that their minimum size is larger than in the diffuse ISM (DISM), which suggests that the mechanisms that lead nano-grains to be photo-destroyed are very efficient below a given critical size limit. The evolution of the nano-grain dust-to-gas mass ratio with both G0 and the effective temperature of the illuminating star indicates a competition between the nano-grain formation through the fragmentation of larger grains and nano-grain photo-destruction. We modelled dust collisions driven by radiative pressure with a classical 1D approach to show that this is a viable scenario for explaining nano-grain formation through fragmentation and, thus, the variations observed in nano-grain dust-to-gas mass ratios from one PDR to another. Conclusions. We find a broad variation in the nano-grain dust properties from one PDR to another, along with a general trend of nano-grain depletion in these regions. We propose a viable scenario of nano-grain formation through fragmentation of large grains due to radiative pressure-induced collisions.
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- 2022
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189. Multiresolution Neural Networks for Imaging
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Paz, Hallison, Novello, Tiago, Silva, Vinicius, Schirmer, Luiz, Schardong, Guilherme, Chagas, Fabio, Lopes, Helio, and Velho, Luiz
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Graphics ,Computer Science - Machine Learning ,68T07, 68U10 ,I.4.10 ,I.3.3 - Abstract
We present MR-Net, a general architecture for multiresolution neural networks, and a framework for imaging applications based on this architecture. Our coordinate-based networks are continuous both in space and in scale as they are composed of multiple stages that progressively add finer details. Besides that, they are a compact and efficient representation. We show examples of multiresolution image representation and applications to texturemagnification, minification, and antialiasing. This document is the extended version of the paper [PNS+22]. It includes additional material that would not fit the page limitations of the conference track for publication.
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- 2022
190. Extending empirical constraints on the SZ-mass scaling relation to higher redshifts via HST weak lensing measurements of nine clusters from the SPT-SZ survey at $z\gtrsim1$
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Zohren, Hannah, Schrabback, Tim, Bocquet, Sebastian, Sommer, Martin, Raihan, Fatimah, Hernández-Martín, Beatriz, Marggraf, Ole, Ansarinejad, Behzad, Bayliss, Matthew B., Bleem, Lindsey E., Erben, Thomas, Hoekstra, Henk, Floyd, Benjamin, Gladders, Michael D., Kleinebreil, Florian, McDonald, Michael A., Schirmer, Mischa, Scognamiglio, Diana, Sharon, Keren, and Wright, Angus H.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a Hubble Space Telescope (HST) weak gravitational lensing study of nine distant and massive galaxy clusters with redshifts $1.0 \lesssim z \lesssim 1.7$ ($z_\mathrm{median} = 1.4$) and Sunyaev Zel'dovich (SZ) detection significance $\xi > 6.0$ from the South Pole Telescope Sunyaev Zel'dovich (SPT-SZ) survey. We measured weak lensing galaxy shapes in HST/ACS F606W and F814W images and used additional observations from HST/WFC3 in F110W and VLT/FORS2 in $U_\mathrm{HIGH}$ to preferentially select background galaxies at $z\gtrsim 1.8$, achieving a high purity. We combined recent redshift estimates from the CANDELS/3D-HST and HUDF fields to infer an improved estimate of the source redshift distribution. We measured weak lensing masses by fitting the tangential reduced shear profiles with spherical Navarro-Frenk-White (NFW) models. We obtained the largest lensing mass in our sample for the cluster SPT-CLJ2040$-$4451, thereby confirming earlier results that suggest a high lensing mass of this cluster compared to X-ray and SZ mass measurements. Combining our weak lensing mass constraints with results obtained by previous studies for lower redshift clusters, we extended the calibration of the scaling relation between the unbiased SZ detection significance $\zeta$ and the cluster mass for the SPT-SZ survey out to higher redshifts. We found that the mass scale inferred from our highest redshift bin ($1.2 < z < 1.7$) is consistent with an extrapolation of constraints derived from lower redshifts, albeit with large statistical uncertainties. Thus, our results show a similar tendency as found in previous studies, where the cluster mass scale derived from the weak lensing data is lower than the mass scale expected in a Planck $\nu\Lambda$CDM (i.e. $\nu$ $\Lambda$ Cold Dark Matter) cosmology given the SPT-SZ cluster number counts., Comment: 23 pages, 10 figures + appendix (9 pages, 9 figures); accepted for publication in A&A
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- 2022
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191. Hardless: A Generalized Serverless Compute Architecture for Hardware Processing Accelerators
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Werner, Sebastian and Schirmer, Trever
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Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
The increasing use of hardware processing accelerators tailored for specific applications, such as the Vision Processing Unit (VPU) for image recognition, further increases developers' configuration, development, and management overhead. Developers have successfully used fully automated elastic cloud services such as serverless computing to counter these additional efforts and shorten development cycles for applications running on CPUs. Unfortunately, current cloud solutions do not yet provide these simplifications for applications that require hardware acceleration. However, as the development of specialized hardware acceleration continues to provide performance and cost improvements, it will become increasingly important to enable ease of use in the cloud. In this paper, we present an initial design and implementation of Hardless, an extensible and generalized serverless computing architecture that can support workloads for arbitrary hardware accelerators. We show how Hardless can scale across different commodity hardware accelerators and support a variety of workloads using the same execution and programming model common in serverless computing today., Comment: Preprint - will be presented at IC2E 2022
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- 2022
192. Euclid preparation. XXIV. Calibration of the halo mass function in $\Lambda(\nu)$CDM cosmologies
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Euclid Collaboration, Castro, T., Fumagalli, A., Angulo, R. E., Bocquet, S., Borgani, S., Carbone, C., Dakin, J., Dolag, K., Giocoli, C., Monaco, P., Ragagnin, A., Saro, A., Sefusatti, E., Costanzi, M., Brun, A. M. C. Le, Corasaniti, P. -S., Amara, A., Amendola, L., Baldi, M., Bender, R., Bodendorf, C., Branchini, E., Brescia, M., Camera, S., Capobianco, V., Carretero, J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Haugan, S. V. H., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kermiche, S., Kitching, T., Kunz, M., Kurki-Suonio, H., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Marulli, F., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Seidel, G., Sirri, G., Stanco, L., Crespí, P. Tallada, Taylor, A. N., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Andreon, S., Bardelli, S., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Lindholm, V., Neissner, C., Scottez, V., Tenti, M., Zucca, E., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Blanchard, A., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Finelli, F., Ganga, K., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilić, S., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maturi, M., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schirmer, M., Sereno, M., Mancini, A. Spurio, Teyssier, R., Valiviita, J., Veropalumbo, A., and Viel, M.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Euclid's photometric galaxy cluster survey has the potential to be a very competitive cosmological probe. The main cosmological probe with observations of clusters is their number count, within which the halo mass function (HMF) is a key theoretical quantity. We present a new calibration of the analytic HMF, at the level of accuracy and precision required for the uncertainty in this quantity to be subdominant with respect to other sources of uncertainty in recovering cosmological parameters from Euclid cluster counts. Our model is calibrated against a suite of N-body simulations using a Bayesian approach taking into account systematic errors arising from numerical effects in the simulation. First, we test the convergence of HMF predictions from different N-body codes, by using initial conditions generated with different orders of Lagrangian Perturbation theory, and adopting different simulation box sizes and mass resolution. Then, we quantify the effect of using different halo-finder algorithms, and how the resulting differences propagate to the cosmological constraints. In order to trace the violation of universality in the HMF, we also analyse simulations based on initial conditions characterised by scale-free power spectra with different spectral indexes, assuming both Einstein--de Sitter and standard $\Lambda$CDM expansion histories. Based on these results, we construct a fitting function for the HMF that we demonstrate to be sub-percent accurate in reproducing results from 9 different variants of the $\Lambda$CDM model including massive neutrinos cosmologies. The calibration systematic uncertainty is largely sub-dominant with respect to the expected precision of future mass-observation relations; with the only notable exception of the effect due to the halo finder, that could lead to biased cosmological inference., Comment: 25 pages, 21 figures, 5 tables, 3 appendixes; v2 matches published version
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- 2022
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193. Applying classical control techniques to quantum systems: entanglement versus stability margin and other limitations
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Weidner, C. A., Schirmer, S. G., Langbein, F. C., and Jonckheere, E. A.
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Quantum Physics - Abstract
Development of robust quantum control has been challenging and there are numerous obstacles to applying classical robust control to quantum system including bilinearity, marginal stability, state preparation errors, nonlinear figures of merit. The requirement of marginal stability, while not satisfied for closed quantum systems, can be satisfied for open quantum systems where Lindbladian behavior leads to non-unitary evolution, and allows for nonzero classical stability margins, but it remains difficult to extract physical insight when classical robust control tools are applied to these systems. We consider a straightforward example of the entanglement between two qubits dissipatively coupled to a lossy cavity and analyze it using the classical stability margin and structured perturbations. We attempt, where possible, to extract physical insight from these analyses. Our aim is to highlight where classical robust control can assist in the analysis of quantum systems and identify areas where more work needs to be done to develop specific methods for quantum robust control., Comment: Accepted to IEEE CDC 2022
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- 2022
194. Behaviour indicative of coprophagy in zoo-managed porcupine (Hystrix indica)
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Polotzek, Martin, Schirmer, Jasmin, Schindler, Judith, and Clauss, Marcus
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- 2023
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195. Characterization of the robotic surgery experience in minimally invasive surgery fellowships from 2010 to 2021
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Haywood, Nathan, Scott, Joshua, Zhang, Aimee, Hallowell, Peter, and Schirmer, Bruce
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- 2023
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196. Histamine H1- and H4-receptor expression in human colon-derived cell lines
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Schrammel, Jasper Carsten, König, Martin, Frommer, Miriam, Andersen, Kaya Saskia, Kirsten, Marla, Seifert, Roland, Neumann, Detlef, and Schirmer, Bastian
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- 2023
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197. Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis
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Hofmann, Annika, Krajnc, Nik, Dal-Bianco, Assunta, Riedl, Christian J., Zrzavy, Tobias, Lerma-Martin, Celia, Kasprian, Gregor, Weber, Claudia E., Pezzini, Francesco, Leutmezer, Fritz, Rommer, Paulus, Bsteh, Gabriel, Platten, Michael, Gass, Achim, Berger, Thomas, Eisele, Philipp, Magliozzi, Roberta, Schirmer, Lucas, and Hametner, Simon
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- 2023
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198. Kardiovaskuläre Therapie bei chronischer Nierenerkrankung
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Brandenburg, Vincent, Saritas, Turgay, Schirmer, Stephan H., Rogacev, Kyrill, and Heine, Gunnar Henrik
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- 2023
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199. Associations between cognitive test scores and pain tolerance: The Tromsø study
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Melum Tonje Anita, Steingrímsdóttir Ólöf A., Jacobsen Henrik B., Johnsen Bente, Stubhaug Audun, Schirmer Henrik, Mathiesen Ellisiv B., and Nielsen Christopher S.
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pain ,cognition ,experimental pain ,cold pressor test ,cuff pressure algometry ,immediate recall test ,digit symbol coding test ,mini-mental state examination ,Special situations and conditions ,RC952-1245 ,Medicine (General) ,R5-920 - Abstract
Previous studies have suggested that experimental pain sensitivity is associated with cognitive function. The aim of this study is to assess this relationship in a large population-based sample.
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- 2024
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200. Acceleration of new medicines–CMC lessons learned from emergency use authorizations
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James Bernstein, Kim Huynh-Ba, Patrick Lynch, Thomas Oliver, Reza Oliyai, Scott W. Roberts, Andrea Schirmer, David Schwinke, Kin Tang, and Jessica Ursin
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Emergency use authorization ,Accelerated regulatory pathways ,Chemistry, Manufacturing, and Controls ,COVID-19 ,Therapeutics. Pharmacology ,RM1-950 ,Pharmacy and materia medica ,RS1-441 - Abstract
Abstract The American Association of Pharmaceutical Scientists (AAPS) Chemistry, Manufacturing, and Control (CMC) Community hosted a virtual panel discussion on July 15, 2022, to provide a forum to discuss industry and regulator CMC challenges associated with emergency use authorizations.
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- 2024
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