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This is a descriptive study done in a qualitative perspective. It aims to describe the conceptions of health care units' managers about the work in public health. The subjects perceptions are that this work goes from interdisciplinary thought with a preventive focus to the curative practice of ambulatory care. On what concerns Nursing, nurses' management functions and auxiliaries assistance activities are pointed out. They believe that strategies to approximate to the SUS principles are necessary in the context of Public Health.

We determined the genotypes of the alcohol dehydrogenase (ALDH) and aldehyde dehydrogenase (ALDH2) loci of different ethnic groups living in Brazil, using saliva DNA amplified by PCR and allele-specific oligonucleotides. Self-reports of flushing reaction after drinking were also studied. The allelic frequencies of ADH2 and ALDH2 were found to be lower than those reported other authors, which might be a result of the admixture origin of the Brazilian population. Variability in facial flushing reaction suggests that other factors play a role in the expression of alcohol-induced flushing.

It approaches the influences of family relationship in the construction of the gender identity process, through the Theory of Objectal Relationship referential, proposed by Chorodow (1979). This theoretical support, emphasizes that the gender identity is basically influenced by the primary bonds established between child and adults, through the continuous personal relationship developing mother and father role. It points out that the gender construction for the boy and for the girl happens in a different way. It concludes pointing out some lines to be adopted by the nurse in the practice with families, as well as, some limitation of the Theory of Objectal Relationship.

The use of microcomputers in medical education to assess the training process in Primary Health Care is analyzed. The experimental study consisted of 8 modules related to immunization campaigns, nursing care of healthy children, sanitation, nursing care of women, epidemiology and statistics, and nursing care of those diseases presenting the highest prevalence. The program is based on the basic software "Evaluation of Training", and designed in basic language. Each module consisted of a set of questions and each set had 3 different forms of feedback: the given form, the controlled form, and the form for searching. The independent variable of this investigation was the evaluation of training by microcomputers, and the dependent variable was the cognitive domain and development. The sample comprises 16 individuals studying on the eighth semester of a nursing course, and each group is made up by 8 students (a control group and an experimental group). Data obtained from this investigation were assessed by the test of nonparametric indicators. Results evidenced that the evaluation of training by a microcomputer provided a significantly higher performance in comparison with noncomputer assisted evaluation. Students were satisfied regarding the interaction with the microcomputer and with the performance of the evaluation. Further investigations in this field are recommended.

Self reports of flushing reaction after drinking, cutaneous sensitivity to alcohol (patch test), and genotypic determination of ADH2, ADH3, and ALDH2 were studied in 53 Brazilian volunteers of different ethnic groups. Genotypes were determined using single-strand conformation polymorphism in discontinuous buffer electrophoresis. Analysis of the results indicated several cases of a reported flushing reaction among ALDH2 1/1 individuals, while all but 2 cases of ALDH2 heterozygotes reported a flushing reaction. The latter subjects also had a negative result in the patch test. These preliminary results indicate that variability in the facial flushing reaction to alcohol seems to be a phenomenon resulting not only from the presence of a deficient ALDH2*2 allele, but also from other polymorphisms of alcohol-metabolizing enzymes.

In order to describe the changing patterns of risk factors for HIV-1 transmission of patients using hospital services at an AIDS referral centre in Porto Alegre, southern Brazil, data on demographic characteristics, referral patterns and risk factors at time of first presentation were collected prospectively on 405 patients between October 1985 and September 1991. Overall HIV-related patient workload increased during the study period, as did the proportion of infected female patients seen (P < 0.05). Of all patients, 147 (36%) presented with symptomatic HIV disease and 77 (19%) presented with an AIDS defining condition; men were more likely to present with symptomatic disease than women. Approximately 156 (44%) of men were self-referred compared with 4 (8%) of the women (P < 0.0001). Of the 357 infected men, 82 (23%) were bisexuals; of the 26 heterosexually infected women, 7 (24%) had bisexual male partners. These data suggest the increasing importance of heterosexual HIV transmission in this hitherto 'low' prevalence area, with male bisexuals constituting an important route through which heterosexual females are being infected in this area. The data also suggest that heterosexual women in Southern Brazil do not perceive themselves to be at risk for HIV-1 infection.

The study aims to explore the utilization of the Formative Evaluation by the microcomputer in the teaching of primary attention to the health. The experiment is composed of eight modules, programmed in Basic software "Formative Evaluation". For each module, a "Question Bank" with three sorts of feedbacks was organized. The sample includes 16 subjects. The results show that the Formative Evaluation by Microcomputer proportioned to the students a cognitive domain significantly higher than the traditional instruction. However, it didn't provide a significantly superior performance to the students who experienced this system.

It has been suggested that exposure to the elevated plus-maze (EPM) apparatus induces antinociceptive effects in mice as measured by the tail-flick assay, which are not blocked by the opiate antagonist naltrexone. The present study performed on 3-month old male EPM-M1 albino mice (12-14 animals per group) was designed to assess a) if exposure limited to the open or to the enclosed arm of the EPM would alter this effect; b) whether or not pharmacologically induced anxiety (1.0 mg/kg pentylenetetrazole, PTZ) would also reduce nociception; c) if exposure to the EPM would alter visceral pain, as measured by the abdominal contortion test. The simultaneous exposure to both the open and enclosed arms of the EPM, but not the exposure limited to each type of arm, led to statistically significant increases in tail withdrawal latencies (TWL). Indeed, 10 min after exposure to both arms, TWL values (mean +/- SEM) were 10.31 +/- 0.87 s as compared to a baseline value of 5.46 +/- 0.53 s. The acute administration of PTZ significantly increased TWL. Conversely, EPM-induced antinociception was not detected by the abdominal contortion test. These results confirm the existence of EPM-induced antinociceptive effects demonstrated by others and show that they may be influenced by multiple determinants.

The effects of nutritional copper deficiency on weight gain, food intake and fertility of pregnant and non-pregnant adult Wistar rats, and weight of newborns, were studied. The adult animals were subjected to diets with different copper content (control-5 ppm; moderate deficiency -1.2 ppm; severe deficiency -0.3 ppm) for six weeks (non-pregnant) and nine weeks (pregnant). No effect on weight gain or appetite was seen in the groups of animals subjected to copper deficiency. Fertility, as evaluated by the number of conceptuses and liverborns of the pregnant animals, and weight of newborns also, were not impaired. These data show that not only the extent of deficiency, but also the period during which it is imposed, as well as its duration, condition the appearance of alterations of this deficiency.

The study does a critical analysis about the nurse's insertion and role in the informatic applied to health. It brings up the importance of nurse's envolvement in the implantation projects of the automatized systems information, the necessity of acquiriment knowledge and control about this technology so that it can be used as a useful work instrument, aiding the decision process and rationalizing the work, with the main objective to improve the nursing practice.

The introduction of informatic tools directed to the Assistence and Administration's support will be able to bring important benefits to Brazilian Nursing. Based on American literature the authors expose some specific applications of the computer in the assistence and administration's actives of nursing, demonstrating the various ways to these actives, in order otimize the assistence rended to the patient.