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Your search keyword '"Šafránek, David"' showing total 155 results
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155 results on '"Šafránek, David"'

151. Integrating Time-Series Data in Large-Scale Discrete Cell-Based Models

Author

Fitime, Louis Fippo, Schuster, Christian, Angel, Peter, Roux, Olivier, Guziolowski, Carito, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Abate, Alessandro, editor, and Šafránek, David, editor

Published
2015
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152. Approximate Probabilistic Verification of Hybrid Systems

Author

Gyori, Benjamin M., Liu, Bing, Paul, Soumya, Ramanathan, R., Thiagarajan, P. S., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Abate, Alessandro, editor, and Šafránek, David, editor

Published
2015
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153. Comparative Statistical Analysis of Qualitative Parametrization Sets

Author

Streck, Adam, Thobe, Kirsten, Siebert, Heike, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Abate, Alessandro, editor, and Šafránek, David, editor

Published
2015
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154. Reconstructing Statistics of Promoter Switching from Reporter Protein Population Snapshot Data

Author

Cinquemani, Eugenio, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Abate, Alessandro, editor, and Šafránek, David, editor

Published
2015
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155. The architecture of regulatory network of metabolism

Author

Geryk, Jan, Flegr, Jaroslav, Cvrčková, Fatima, and Šafránek, David

Subjects
regulační síť metabolismu, metabolic network, metabolická síť, alosteric regulation of enzymes, modularity, graph theory, modularita, regulatory network of metabolism, alosterické regulace enzymů, teorie grafů
Abstract

The thesis focus on the modularity of metabolic network and foremost on the architecture of regulatory network representing direct regulatory interactions between metabolites and enzymes. I focus on the "modularity measure" in my first work. Modularity measure is quantitative measure of network modularity commonly used for module identification. It was showed that algorithms using this measure can produce modules that are composed of two clearly pronounced sub-modules. Maximum size of module for which there is a risk that is is composed of two sub-modules is called resolution limit of modularity measure. In my first work I generalize resolution limit of modularity measure. The generalized version provide insight to the origin of resolution limit in the null-model used by modularity measure. Moreover it is showed that the risk of omitting of sub-modular structures applies for bigger modules than mentioned in the original publication. The second work is focused on the question how does the modular structure of E. coli metabolic network change if we add regulatory interactions. I find that the modularity of modular core of network slightly increase after regulatory edges addition. The modularity increase is significant with respect to randomized ensemble of regulatory networks. Identified modules...

Published
2013

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