437 results on '"Rummel-Kluge, Christine"'
Search Results
152. Caregiver psychoeducation for schizophrenia: Is gender important? – Comments on the study by McWilliams et al., 2007
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Pitschel-Walz, Gabriele, primary, Rummel-Kluge, Christine, additional, Reichhart, Tatjana, additional, Bäuml, Josef, additional, and Kissling, Werner, additional
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- 2007
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153. Quetiapine versus other atypical antipsychotics for schizophrenia
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Komossa, Katja, primary, Hunger, Heike, additional, Schmidt, Franziska, additional, Schwarz, Sandra, additional, Leucht, Stefan, additional, Srisurapanont, Manit, additional, and Rummel-Kluge, Christine, additional
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- 2007
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154. Risperidone versus other atypical antipsychotics for schizophrenia
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Komossa, Katja, primary, Hunger, Heike, additional, Schmidt, Franziska, additional, Schwarz, Sandra, additional, Leucht, Stefan, additional, and Rummel-Kluge, Christine, additional
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- 2007
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155. Olanzapine versus other atypical antipsychotics for schizophrenia
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Komossa, Katja, primary, Rummel-Kluge, Christine, additional, Hunger, Heike, additional, Schmid, Franziska, additional, Schwarz, Sandra, additional, Duggan, Lorna, additional, Kissling, Werner, additional, and Leucht, Stefan, additional
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- 2007
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156. Ziprasidone versus other atypical antipsychotics for schizophrenia
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Komossa, Katja, primary, Rummel-Kluge, Christine, additional, Hunger, Heike, additional, Schmidt, Franziska, additional, Schwarz, Sandra, additional, Bhoopathi, Paranthaman Seth S, additional, and Leucht, Stefan, additional
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- 2007
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157. Aripiprazole versus other atypical antipsychotics for schizophrenia
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Komossa, Katja, primary, Rummel-Kluge, Christine, additional, Schmidt, Franziska, additional, Hunger, Heike, additional, Schwarz, Sandra, additional, El-Sayeh, Hany George G, additional, Kissling, Werner, additional, and Leucht, Stefan, additional
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- 2007
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158. Clozapine versus other atypical antipsychotics for schizophrenia
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Asenjo Lobos, Claudia, primary, Komossa, Katja, additional, Rummel-Kluge, Christine, additional, Hunger, Heike, additional, Schmid, Franziska, additional, Schwarz, Sandra, additional, and Leucht, Stefan, additional
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- 2007
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159. Antidepressants for the negative symptoms of schizophrenia
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Rummel-Kluge, Christine, primary, Kissling, Werner, additional, and Leucht, Stefan, additional
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- 2006
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160. Antipsychotic combinations for schizophrenia
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Correll, Christoph U, primary, Kissling, Werner, additional, Rummel-Kluge, Christine, additional, and Leucht, Stefan, additional
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- 2003
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161. New generation antipsychotics for first episode schizophrenia
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Hamann, Johannes, primary, Kissling, Werner, additional, Leucht, Stefan, additional, and Rummel-Kluge, Christine, additional
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- 2003
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162. Innovative Strategien zur Förderung der Compliance von Patienten mit Schizophrenie – „Peer–to–peer–Psychoedukation” und „Peer–to–peer–Sprechstunde”
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Rummel–Kluge, Christine and Hansen, Wulf–Peter
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- 2008
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163. Efficacy of a Guided Web-Based Self-Management Intervention for Depression or Dysthymia: Randomized Controlled Trial With a 12-Month Follow-Up Using an Active Control Condition.
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Oehler, Caroline, Görges, Frauke, Rogalla, Mandy, Rummel-Kluge, Christine, and Hegerl, Ulrich
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Background: An increasing number of studies suggest that web-based interventions for patients with depression can reduce their symptoms and are expected to fill currently existing treatment gaps. However, evidence for their efficacy has mainly been derived from comparisons with wait-list or treatment as usual controls. In particular, designs using wait-list controls are unlikely to induce hope and may even have nocebo effects, making it difficult to draw conclusions about the intervention's efficacy. Studies using active controls are rare and have not yielded conclusive results.Objective: The main objective of this study is to assess the acute and long-term antidepressant efficacy of a 6-week, guided, web-based self-management intervention building on the principles of cognitive behavioral therapy (iFightDepression tool) for patients with depression compared with web-based progressive muscle relaxation as an active control condition.Methods: A total of 348 patients with mild-to-moderate depressive symptoms or dysthymia (according to the Mini International Neuropsychiatric Interview) were recruited online and randomly assigned to 1 of the 2 intervention arms. Acute antidepressant effects after 6 weeks and long-term effects at 3-, 6-, and 12-month follow-up were studied using the Inventory of Depressive Symptomatology-self-rating as a primary outcome parameter and change in quality of life (Short Form 12) and user satisfaction (client satisfaction questionnaire) as secondary outcome parameters. Treatment effects were assessed using mixed model analyses.Results: Over the entire observation period, a greater reduction in symptoms of depression (P=.01) and a greater improvement of life quality (P<.001) was found in the intervention group compared with the active control group. Separate tests for each time point revealed significant effects on depressive symptoms at the 3-month follow-up (d=0.281; 95% CI 0.069 to 0.493), but not after 6 weeks (main outcome:d=0.192; 95% CI -0.020 to 0.404) and 6 and 12 months. The intervention was significantly superior to the control condition with respect to user satisfaction (25.31 vs 21.97; t259=5.804; P<.01).Conclusions: The fact that antidepressant effects have been found for a guided self-management tool in comparison with an active control strengthens the evidence base for the efficacy of web-based interventions. The antidepressant effect became most prominent at the 3-month follow-up. After 6 weeks of intervention, significant positive effects were observed on life quality but not on depressive symptoms. Although the effect size of such web-based interventions on symptoms of depression might be smaller than that suggested by earlier studies using wait-list control conditions, they can be a cost-effective addition to antidepressants and face-to-face psychotherapy.Trial Registration: International Clinical Trials Registry Platform ICTRP080-15-09032015; https://apps.who.int/trialsearch/Trial2.aspx?TrialID=DRKS00009323. [ABSTRACT FROM AUTHOR]- Published
- 2020
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164. Intentions and barriers to help-seeking in adolescents and young adults differing in depression severity: cross-sectional results from a school-based mental health project.
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Baldofski, Sabrina, Scheider, Jelena, Kohls, Elisabeth, Klemm, Sarah-Lena, Koenig, Julian, Bauer, Stephanie, Moessner, Markus, Kaess, Michael, Eschenbeck, Heike, Lehner, Laya, Becker, Katja, Krämer, Jennifer, Diestelkamp, Silke, Thomasius, Rainer, and Rummel-Kluge, Christine
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CROSS-sectional method , *HIGH schools , *HEALTH literacy , *FEAR , *QUALITATIVE research , *AUTONOMY (Psychology) , *DATA analysis , *QUESTIONNAIRES , *CONTENT analysis , *SOCIAL factors , *KRUSKAL-Wallis Test , *HELP-seeking behavior , *SEVERITY of illness index , *DESCRIPTIVE statistics , *CHI-squared test , *ANALYSIS of covariance , *TEENAGERS' conduct of life , *INTENTION , *SCHOOL mental health services , *RESEARCH , *STATISTICS , *COMPARATIVE studies , *DATA analysis software , *SHAME , *MENTAL depression , *SOCIAL stigma - Abstract
Background: Mental health problems, such as depression, have a high prevalence in young people. However, the majority of youths suffering from depression do not seek professional help. This study aimed to compare help-seeking behavior, intentions and perceived barriers between youthswith different levels of depressive symptoms. Methods: This cross-sectional study is part of a large-scale, multi-center project. Participants were n = 9509 youths who were recruited in German schools and completed a baseline screening questionnaire. Based on their depressive symptoms, youths were allocated to the following three subgroups: (a) without depressive symptoms, (b) with subclinical symptoms, (c) with clinical symptoms (measured by PHQ-A). Quantitative analyses compared previous help-seeking behavior, help-seeking intentions and perceived barriers (Barriers questionnaire) between these subgroups. An additional exploratory qualitative content analysis examined text answers on other perceived barriers to help-seeking. Results: Participants were mostly female (n = 5575, 58.6%) and 12 to 24 years old (M = 15.09, SD 2.37). Participants with different levels of depressive symptoms differed significantly in help-seeking behavior, intentions and perceived barriers. Specifically, participants with clinical depressive symptoms reported more previous help-seeking, but lower intentions to seek help compared to participants without symptoms (all p < 0.05). Participants with subclinical depressive symptoms reported a similar frequency of previous help-seeking, but higher intentions to seek help compared to participants without symptoms (all p < 0.05). Perception of barriers was different across subgroups: participants with clinical and subclinical depressive symptoms perceived the majority of barriers such as stigma, difficulties in accessibility, and family-related barriers as more relevant than participants without depressive symptoms. Across all subgroups, participants frequently mentioned intrapersonal reasons, a high need for autonomy, and a lack of mental health literacy as barriers to help-seeking. Conclusions: Youths with higher levels of depressive symptoms are more reluctant to seek professional help and perceive higher barriers. This underlines the need for effective and low-threshold interventions to tackle barriers, increase help-seeking, and lower depressive symptoms in adolescents and young adults differing in depression severity. Trial registration: DRKS00014685. [ABSTRACT FROM AUTHOR]
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- 2024
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165. Efficacy of an internet-based self-management intervention for depression or dysthymia – a study protocol of an RCT using an active control condition.
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Oehler, Caroline, Görges, Frauke, Böttger, Daniel, Hug, Juliane, Koburger, Nicole, Kohls, Elisabeth, and Rummel-Kluge, Christine
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DYSTHYMIC disorder ,CLINICAL trial registries ,RANDOMIZED controlled trials - Abstract
Background: The treatment of major depressive disorder, a highly prevalent disorder associated with pronounced burden, is a large challenge to healthcare systems worldwide. Internet based self-management interventions seem to be a cost effective way to complement the treatment of depressed patients, but the accumulating evidence is mainly based on the comparison to waitlist controls and treatment as usual, which might lead to an overestimation of effects. Furthermore, studies assessing long-term effects and possible negative outcomes are still rare. Methods/Design: The proposed study evaluates the efficacy of the German version of the iFightDepression® tool in comparison to an active control condition. A total of 360 patients with mild to moderate depressive symptoms are included into a two-armed randomized controlled trial. They receive one of two six week interventions; either the iFightDepression® tool or progressive muscle relaxation serving as the control condition. Both intervention groups receive information material, weekly tasks via the internet and regular phone calls as part of the intervention. The primary outcome is change in depressive symptoms after the intervention period, as measured with the Inventory of Depressive Symptomatology. Satisfaction with the program, usability, changes in perceived quality of life, and possible negative effects are assessed as secondary outcomes. Discussion: This study represents the first randomized controlled trial on the iFightDepression® self-management tool in its German version, aiming at efficacy, but also at providing new insights into so far understudied aspects of E-mental health programs, namely the specificity of the treatment effect compared to an active control condition, it's continuity over a time course of 12 months, and possible negative effects of these internet based interventions. Trial registration: International trial-registration took place through the "international clinical trials registry platform" (WHO) with the secondary ID 080–15-09032015. German Clinical Trial Registration: DRKS00009323 (DRKS.de, registered on 25 February 2016). [ABSTRACT FROM AUTHOR]
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- 2019
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166. Effectiveness of a web-based screening and brief intervention with weekly text-message-initiated individualised prompts for reducing risky alcohol use among teenagers: study protocol of a randomised controlled trial within the ProHEAD consortium.
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Diestelkamp, Silke, Wartberg, Lutz, Kaess, Michael, Bauer, Stephanie, Rummel-Kluge, Christine, Becker, Katja, Eschenbeck, Heike, Salize, Hans-Joachim, Moessner, Markus, Baldus, Christiane, Arnaud, Nicolas, Thomasius, Rainer, and ProHEAD consortium
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ALCOHOL drinking ,RANDOMIZED controlled trials ,BINGE drinking ,ADOLESCENCE ,MENTAL health ,QUALITY of life ,ALCOHOL drinking prevention ,BEHAVIOR ,CLINICAL trials ,EXPERIMENTAL design ,INTERNET ,HEALTH outcome assessment ,RESEARCH funding ,STATISTICS ,TEXT messages ,SAMPLE size (Statistics) ,DATA analysis ,PATIENT selection - Abstract
Background: Early and excessive alcohol use is a significant threat to healthy development. Evidence supports the effectiveness of electronic alcohol interventions for young drinkers. However, effects are typically small and studies targeting under 18-year-olds are scarce. This trial is the first to evaluate the effectiveness of a single-session, brief, motivational, web-based intervention (ProWISE) plus weekly text-message-initiated individualised prompts (TIPs) in reducing alcohol consumption and alcohol-related harm among children and adolescents aged ≥ 12 years. TIPs are designed to decrease risky alcohol use by reaching youth in the contexts of their everyday lives and by providing individualised feedback on drinking intentions, actual drinking and succession in achieving personal goals for low-risk drinking or abstinence.Methods/design: The trial is part of the multicentre consortium ProHEAD testing e-interventions for mental health problems in children and adolescents. Participants in grades 6-13 aged ≥ 12 years will be recruited in schools which participate in ProHEAD (target N = 15,000). Main criterion for inclusion in the ProWISE-TIP trial is a positive screening for at-risk alcohol use in the CRAFFT-d questionnaire (target n = 1076). In a multicentre, four-arm, randomised controlled design the following groups will be compared: (A) web-based intervention plus TIPs for 12 weeks; (B) web-based intervention plus text-message-initiated assessment of alcohol consumption for 12 weeks; (C) web-based intervention only; and (D) alcohol-related psychoeducation. TIPs will be delivered shortly before and after high-risk situations for excessive alcohol use and will be tailored to age, gender, drinking motives and alcohol consumption. Study participants will be followed up at three, six and nine months in the ProWISE-TIP trial and at one and two years in the ProHEAD consortium. Primary outcome is alcohol use in the past 30 days at nine months after enrolment. Secondary outcomes are alcohol-related problems, co-occurring substance use, health service utilisation, mental health problems and quality of life.Discussion: Trial results will generate important evidence on how to enhance effectiveness of single-session, web-based alcohol interventions for youth. The ProWISE-TIP intervention, if effective, can be used as a stand-alone alcohol intervention or as an add-on to school-based or community-based alcohol prevention programs.Trial Registration: German Clinical Trials Register, DRKS00014606 Registered on 20 April 2018. [ABSTRACT FROM AUTHOR]- Published
- 2019
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167. School-based mental health promotion in children and adolescents with StresSOS using online or face-to-face interventions: study protocol for a randomized controlled trial within the ProHEAD Consortium.
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Eschenbeck, Heike, Lehner, Laya, Hofmann, Hanna, Bauer, Stephanie, Becker, Katja, Diestelkamp, Silke, Kaess, Michael, Moessner, Markus, Rummel-Kluge, Christine, Salize, Hans-Joachim, and ProHEAD Consortium
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MENTAL health ,SCHOOL environment ,TEENAGERS ,RANDOMIZED controlled trials ,STRESS management - Abstract
Background: Schools are an ideal setting in which to promote health. However, empirical data on the effectiveness of school-based mental health promotion programs are rare, and research on universal Internet-based prevention in schools is almost non-existent. Following the life skills approach, stress management training is an important component of health promotion. Mental health literacy is also associated with mental health status, and it facilitates formal help-seeking by children and adolescents (C&A). The main objectives of this study are (1) the development and evaluation of an Internet-based version of a universal school-based health promotion program called StresSOS and (2) demonstrating non-inferiority of the online setting compared to the face-to-face setting. StresSOS aims to improve stress management and mental health literacy in C&A.Methods/design: A school-based sample of 15,000 C&A (grades 6-13 and older than 12 years) will be recruited in five regions of Germany within the ProHEAD Consortium. Those with a screening result at baseline indicating no mental health problems will be invited to participate in a randomized controlled trial comparing StresSOS online to an active online control condition (Study A). In addition, 420 adolescents recruited as a separate school-based sample will participate in the StresSOS face-to-face intervention. Participants in both intervention groups (online or face-to-face) will receive the same eight treatment modules to allow for the comparison of both methods of delivery (Study B). The primary outcome is the number of C&A with symptoms of mental health problems at a 12 months follow-up. Secondary outcomes are related to stress/coping (i.e., knowledge, symptoms of stress, coping resources), mental health literacy (knowledge and attitudes toward mental disorders and help-seeking), program usage patterns, cost-effectiveness, and acceptability of the intervention.Discussion: This study represents the first adequately powered non-inferiority trial in the area of school-based mental health promotion. If online StresSOS proves efficacious and non-inferior to face-to-face delivery, this offers great potential for health promotion in youths, both in and outside the school environment.Trial Registration: German Clinical Trials Register, DRKS00014693 . Registered on 14 May 2018. [ABSTRACT FROM AUTHOR]- Published
- 2019
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168. Efficacy and cost-effectiveness of two online interventions for children and adolescents at risk for depression (E.motion trial): study protocol for a randomized controlled trial within the ProHEAD consortium.
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Baldofski, Sabrina, Kohls, Elisabeth, Bauer, Stephanie, Becker, Katja, Bilic, Sally, Eschenbeck, Heike, Kaess, Michael, Moessner, Markus, Salize, Hans Joachim, Diestelkamp, Silke, Voß, Elke, Rummel-Kluge, Christine, and ProHEAD consortium
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DEPRESSION in children ,MENTAL depression ,DEPRESSION in adolescence ,HELP-seeking behavior ,COST effectiveness ,TREATMENT effectiveness - Abstract
Background: Depression is a serious mental health problem and is common in children and adolescents. Online interventions are promising in overcoming the widespread undertreatment of depression and in improving the help-seeking behavior in children and adolescents.Methods: The multicentre, randomized controlled E.motion trial is part of the German ProHEAD consortium (Promoting Help-seeking using E-technology for ADolescents). The objective of the trial is to investigate the efficacy and cost-effectiveness of two online interventions to reduce depressive symptomatology in high-risk children and adolescents with subsyndromal symptoms of depression in comparison to an active control group. Participants will be randomized to one of three conditions: (1) Intervention 1, a clinician-guided self-management program (iFightDepression®); (2) Intervention 2, a clinician-guided group chat intervention; and (3) Control intervention, a psycho-educational website on depressive symptoms. Interventions last six weeks. In total, N = 363 children and adolescents aged ≥ 12 years with Patient Health Questionnaire-9 modified for Adolescents (PHQ-A) scores in the range of 5-9 will be recruited at five study sites across Germany. Online questionnaires will be administered before onset of the intervention, at the end of the intervention, and at the six-month follow-up. Further, children and adolescents will participate in the baseline screening and the one- and two-year school-based follow-up assessments integrated in the ProHEAD consortium. The primary endpoint is depression symptomatology at the end of intervention as measured by the PHQ-A score. Secondary outcomes include depression symptomatology at all follow-ups, help-seeking attitudes, and actual face-to-face help-seeking, adherence to and satisfaction with the interventions, depression stigma, and utilization and cost of interventions.Discussion: This study represents the first randomized controlled trial (RCT) investigating efficacy and cost-effectiveness of two online interventions in children and adolescents aged ≥ 12 years at risk for depression. It aims to provide a better understanding of the help-seeking behavior of children and adolescents, potential benefits of E-mental health interventions for this age group, and new insights into so far understudied aspects of E-mental health programs, such as potential negative effects of online interventions. This knowledge will be used to tailor and improve future help offers and programs for children and adolescents and ways of treatment allocation.Trial Registration: German Register for Clinical Trials (DRKS), DRKS00014668 . Registered on 4 May 2018. International trial registration took place through the "international clinical trials registry platform" with the secondary ID S-086/2018. [ABSTRACT FROM AUTHOR]- Published
- 2019
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169. International and domestic university students' mental health over the course of the COVID-19 pandemic in Germany: Comparison between 2020, 2021, and 2022.
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Prado, Aneliana da Silva, Baldofski, Sabrina, Kohls, Elisabeth, and Rummel-Kluge, Christine
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MENTAL health services , *COVID-19 pandemic , *COLLEGE students , *MENTAL health of students , *FOREIGN students , *MENTAL depression - Abstract
Background: The COVID-19 pandemic affected university students' mental health worldwide. International students were presenting high levels of stress, anxiety, and depressive symptoms before the pandemic. This study aimed to investigate (i) differences between various timepoints of the COVID-19 pandemic (2020, 2021, and 2022) in mental health outcomes and social and emotional aspects in domestic and international students, separately, (ii) differences between international and domestic students between the three timepoints on mental health outcomes and social and emotional aspects, and (iii) possible moderation effects of timepoints on mental health outcomes and social and emotional aspects of domestic and international students. Material and methods: Data from three cross-sectional anonymous online surveys conducted in German universities were analyzed and compared. Data were collected in 2020, 2021, and 2022, respectively, with a total N = 14,498. Depressive symptoms, hazardous alcohol use, social support, self-efficacy, resilience, perceived stress, and loneliness were assessed through standardized self-report instruments. Differences between domestic and international students in mental health outcomes, and social and emotional aspects across three timepoints were assessed with one-way and two-way ANCOVAs. Results: Regardless of the timepoint, international students presented more depressive symptoms and perceived stress, lower perceived social support and resilience, but higher levels of self-efficacy and less alcohol consumption compared to domestic students. A significant interaction effect between timepoint and student status emerged only for loneliness. Conclusions: International students generally presented poorer mental health outcomes than domestic students. Mental health care and prevention such as low-threshold, online counseling should address university students, especially international students. [ABSTRACT FROM AUTHOR]
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- 2024
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170. Info-Telefon Depression – eine explorative Analyse von Anruferdaten eines bundesweiten Informationsangebots zu depressiven Erkrankungen.
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Görges, Frauke, Gravert, Christian, Rummel-Kluge, Christine, and Hegerl, Ulrich
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- 2020
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171. Differences in Help-Seeking Behavior among University Students during the COVID-19 Pandemic Depending on Mental Health Status: Results from a Cross-Sectional Survey.
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Guenthner, Lukas, Baldofski, Sabrina, Kohls, Elisabeth, Schuhr, Jan, Brock, Tanja, and Rummel-Kluge, Christine
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MENTAL health services , *HELP-seeking behavior , *COVID-19 pandemic , *MENTAL health , *STUDENT health services , *MENTAL health of students , *SUICIDE victims - Abstract
Background: Current evidence suggests that a significant proportion of university students are affected by mental disorders and suicidal ideation. Despite this, a treatment gap exists. Therefore, the present study assessed students' knowledge and past use of on- and off-campus mental health services and help-seeking intentions. Furthermore, resilience was investigated as a potential barrier to help-seeking behavior. Methods: Data were collected between April and May 2022 from N = 5510 students from Saxony, Germany. To compare dependent variables, subgroups were computed according to students' mental health status. Variables were assessed using standardized questionnaires. Chi-square tests were used for comparisons between groups. Multiple regression models were used to investigate the influence of resilience on help-seeking behavior. Results: Between 34 and 38% (depending on the subgroup) of participants indicated that they were not aware of their universities' psychosocial counseling services. Furthermore, between 17 and 19% of participants indicated that they were not willing to seek help from professional mental health services. Finally, the previously found negative effect of resilience on help-seeking behavior was confirmed. Conclusion: The results showed a lack of awareness regarding universities' mental health services and a treatment gap among university students. Universities and healthcare providers need to educate students about mental health services and how to access them. Further research is needed to elucidate the differential impact of resilience on mental health and help-seeking. [ABSTRACT FROM AUTHOR]
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- 2023
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172. How are Brazilian university students coping with the COVID-19 pandemic? Results of an online survey on psychosocial well-being, perceived burdens, and attitudes toward social distancing and vaccination.
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Prado, Aneliana da Silva, Kohls, Elisabeth, Baldofski, Sabrina, Bianchi, Alessandra Sant'Anna, Trindade, Luciano Imar Palheta, Freitas, Joanneliese de Lucas, and Rummel-Kluge, Christine
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COVID-19 pandemic , *SOCIAL attitudes , *HEALTH attitudes , *MEDICAL personnel , *SOCIAL distancing - Abstract
Background: The COVID-19 pandemic caused significant disruption to education systems worldwide, increasing pre-existing concerns regarding university students' mental health. Brazil was among the countries most affected by COVID-19 cases and deaths and was considered a pandemic epicenter. This study aimed to investigate Brazilian university students' mental health status and perceived burdens during the COVID-19 pandemic. Material and methods: From November 2021 to March 2022, a cross-sectional and anonymous online survey was conducted among students of a Brazilian federal university. Mental health status (depressive symptoms, alcohol and drug consumption) and social and emotional aspects in the pandemic context (social support, perceived stress, loneliness, resilience, and self-efficacy) were assessed with standardized measures. Students' attitudes toward the COVID-19 pandemic and vaccination and perceived burdens of the pandemic were also investigated. Results: A total of N = 2,437 students completed the online survey. The PHQ-9 mean sum score was 12.85 (SD = 7.40), while n = 1,488 (61.10%) participants reported a sum score of 10 or more, indicating clinically relevant depressive symptoms. Further, n = 808 (33.1%) of the total sample reported suicidal thoughts. Levels of depressive symptoms, perceived stress, and loneliness were higher among undergraduate/bachelor students than doctoral students. Almost all participants (97.3%) reported being fully vaccinated against COVID-19. Multiple regression analyses showed that being single, having an income decreased during the pandemic, having a previous mental illness, having a chronic somatic condition, not finding positive aspects in the pandemic, lower self-efficacy, lower social support, lower resilience, and higher experienced loneliness were significantly associated with higher levels of depression. Conclusions: The study showed high levels of depressive symptoms and suicidal ideation among Federal University of Parana students. Therefore, health care providers and universities need to recognize and address mental health issues; psychosocial policies must be enhanced to mitigate the impact of the pandemic on students' mental health and wellbeing. [ABSTRACT FROM AUTHOR]
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- 2023
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173. Help‐seeking attitudes and behaviours for mental health problems in adolescents before and during the first COVID‐19 school closures in Germany.
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Lustig, Sophia, Koenig, Julian, Bauer, Stephanie, Moessner, Markus, Bonnet, Sabrina, Becker, Katja, Diestelkamp, Silke, Eschenbeck, Heike, Hiery, Alisa, Kohls, Elisabeth, Lehner, Laya, Rummel‐Kluge, Christine, Thomasius, Rainer, and Kaess, Michael
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COVID-19 pandemic , *HEALTH behavior , *MENTAL illness , *HELP-seeking behavior , *SCHOOL closings , *ATTITUDES toward illness - Abstract
Aim: Comparing measures of psychological wellbeing and help‐seeking in youths before and within the first school closures due to the coronavirus disease 2019 (COVID‐19) pandemic enables a better understanding of the effects the pandemic has for those seeking professional help for mental health problems. Methods: Data were obtained from the Germany‐based ProHEAD school study. Pre‐lockdown and lockdown samples (n = 648) were compared regarding pupils' psychological wellbeing, help‐seeking attitudes and help‐seeking behaviour. Results: Participants from the lockdown sample showed greater positive attitudes towards seeking professional help, whereas psychological wellbeing and help‐seeking behaviour remained stable. Conclusions: Possible explanations may include an increased public discourse on mental health or self‐selection bias for participation during lockdown. [ABSTRACT FROM AUTHOR]
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- 2023
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174. Review: extrapyramidal side effects vary between different second-generation antipsychotic drugs.
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Rummel-Kluge, Christine and Caroff, Stanley N.
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- 2012
175. The impact of COVID-19 related lockdown measures on self-reported psychopathology and health-related quality of life in German adolescents.
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Koenig, Julian, Kohls, Elisabeth, Moessner, Markus, Lustig, Sophia, Bauer, Stephanie, Becker, Katja, Thomasius, Rainer, Eschenbeck, Heike, Diestelkamp, Silke, Gillé, Vera, Hiery, Alisa, Rummel-Kluge, Christine, Kaess, Michael, Bonnet, Sabrina, Hammon, Stella, Richter, Regina, Bertsch, Katja, Brunner, Romuald, Feldhege, Johannes, and Gallinat, Christina
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SELF-evaluation , *HEALTH status indicators , *ADOLESCENT health , *QUALITY of life , *PATHOLOGICAL psychology , *DESCRIPTIVE statistics , *RESEARCH funding , *STAY-at-home orders , *STATISTICAL sampling , *COVID-19 pandemic - Abstract
The impact of school-closings on adolescents' mental health and well-being in the management of the ongoing COVID-19 pandemic is subject to ongoing public debate. Reliable data to inform a balanced discussion are limited. Drawing on a large ongoing multi-site project in Germany, we assessed differences in self-reported psychopathology in a matched convenience-sample of adolescents assessed pre- (November 26, 2018 to March 13, 2020; n = 324) and post the first lockdown (March 18, 2020 to August 29, 2020; n = 324) early 2020 in Germany. We found no evidence for an increase in emotional and behavioral problems, depression, thoughts of suicide or suicide attempts, eating disorder symptoms, or a decrease in general health-related quality of life. Reported suicide plans significantly decreased from 6.14 to 2.16%. Similarly, conduct problems decreased in the post-lockdown period. Family risk-factors did not moderate these findings. The influence of socioeconomic status on emotional and behavioral problems as well as depression decreased during the lockdown. Based on the present findings, the first school-closing in Germany had no immediate and severe impact on adolescents' well-being. However, caution is warranted as our data covers a fairly small, affluent sample over a limited time-span and long-term consequences cannot be ruled out. [ABSTRACT FROM AUTHOR]
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- 2023
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176. Efficacy of computer- and/or internet-based cognitive-behavioral guided self-management for depression in adults: a systematic review and meta-analysis of randomized controlled trials.
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Mamukashvili-Delau, Megi, Koburger, Nicole, Dietrich, Sandra, and Rummel-Kluge, Christine
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RANDOMIZED controlled trials , *SELF-help techniques , *TELEPHONE calls , *MENTAL depression , *GREY literature , *ADULTS - Abstract
Background: Depression is a worldwide disease. CBT-based self-help treatment allows patients with mild to moderate depression symptoms to improve their depression or to bridge the waiting- or pandemic period until they receive further clinical treatment. Objective: This systematic review and meta-analysis aims to explore the efficacy, acceptability and improvement in quality of life of computer-delivered and/or internet-based CBT self-help interventions with minimal guidance (up to 10 min) for depression. The second aim was to compare the effectiveness of reducing depression symptoms at post-treatment of treatment by the type of minimal guidance: (1) e-mail, (2) telephone calls, (3) e-mail and telephone together, or (4) face-to-face. Methods: The Cochrane depression, anxiety, and neurosis review group's specialized register electronic searches, grey literature, reference lists and correspondence were used to search for published and unpublished RCTs that reported efficacy of computer- and/or internet-based CBT self-help treatments for depression with minimal guidance up to 10 min per week. Methodological quality of included studies was evaluated with Cochrane Collaboration tools for assessing risk of bias. The meta-analysis was accomplished using the RevMen software. Results: In total, 2809 study abstracts were checked for eligibility. Out of these, 19 studies (21 samples) with a total of 3226 participants were included. The results showed that concerning efficacy, the treatment group is superior to the control group with a medium to large effect size of 0.65. Also, treatment groups with combined guidance by e-mail and telephone calls together had greater effects (SMD -0.76) than groups with other types of minimal guidance (guided by e-mail SMD -0.63; guided face to-face SMD – 0.66; guided by telephone calls SMD -0.49). Findings showed also, that iCBT with minimal guidance had small but statistically significant effect size of 0.28 in improving quality of life. Moreover, there were higher drop-out rates in the treatment condition (RR 1.36) than in the control groups. Conclusions: The results of this meta-analysis support the efficacy of computer- and/or internet-based CBT self-help programs with minimal weekly guidance up to only 10 min for improving depression symptoms at post-treatment for adults. In addition, the results are pointing towards two practical implications. Firstly, depressed persons can use self-help treatment with minimal guidance at home to improve their symptoms or to bridge the waiting time – or pandemic period – before they receive professional face-to-face treatment. Secondly, it can help clinicians to make the decision about using CBT-based self-help treatments for patients that do not need urgent professional treatment, or to combine it with face-to-face therapy. [ABSTRACT FROM AUTHOR]
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- 2022
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177. Stable through the COVID-19 pandemic: Results from a longitudinal telephone interview study in psychiatric outpatients.
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Kertzscher, Lisa, Baldofski, Sabrina, Kohls, Elisabeth, Schomerus, Georg, and Rummel-Kluge, Christine
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COVID-19 pandemic , *TELEPHONE interviewing , *MEDICAL care , *ATTENTION-deficit hyperactivity disorder , *SOCIAL attitudes , *DEEP brain stimulation - Abstract
Background: The COVID-19 pandemic was associated with far-reaching changes all over the world. Health care systems were and are also affected. Little is known about the impact of these changes and the duration of the pandemic on people with mental disorders. The aim of this longitudinal follow-up study was to investigate the mental health status, medical care provision, and attitudes towards the pandemic of these people at the end of the second pandemic lockdown in Germany in 2021, and to compare these findings with the results of 2020. Methods: People with mental disorders currently receiving treatment in the psychiatric outpatient department of the University Hospital Leipzig, Germany, were asked about depressive symptoms (PHQ-9), self-reported medical care provision, attitudes and social and emotional aspects of the pandemic (social support [ESSI], perceived stress [PSS-4], loneliness [UCLA-3-LS], and resilience [BRS]) using structured telephone interviews. Results: In total, N = 75 participants who had already participated in the first survey in 2020 took part in the follow-up telephone interviews. The most frequent clinician-rated diagnoses were attention deficit disorder/attention deficit hyperactivity disorder (n = 21; 28.0%) and obsessive-compulsive disorder (n = 16; 21.3%). In comparison to 2020, a significantly higher proportion of participants reported no problems in receiving medical care provision. Compared to the previous year, the resilience of the participants had significantly decreased. Depressive symptoms, social support, perceived stress, and loneliness remained stable. Significantly more participants felt restricted by the pandemic-related government measures in 2021 than in 2020. Conclusions: This study highlights the importance for continued efforts to maintain stable medical care provision for people with mental disorders during the COVID-19 pandemic, as except for a decrease in resilience, mental health status remained stable. Nonetheless there is still a need for continued treatment to stabilise and improve this status. [ABSTRACT FROM AUTHOR]
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- 2022
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178. Celebrity suicide on the railway network: Can one case trigger international effects?
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Koburger, Nicole, Mergl, Roland, Rummel-Kluge, Christine, Ibelshäuser, Angela, Meise, Ullrich, Postuvan, Vita, Roskar, Saska, Székely, András, Ditta Tóth, Mónika, van der Feltz-Cornelis, Christina, and Hegerl, Ulrich
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COPYCAT suicide , *SOCCER goalkeepers , *JOINT use of railroad facilities , *FAME - Abstract
Background After the railway suicide of the German national goalkeeper Robert Enke in 2009, a significant increase of railway suicides was observed nationally. This study analyses whether this incident also triggered copycat effects in other European countries. Additionally, media coverage proxied by Google Trends and long-term changes taking into account general changes in suicide rates and kilometres driven by trains were examined. Methods The numbers of railway suicides before and after Enke´s suicide were analysed for short and long-term periods (2 weeks and 2 years post-event) across five European countries. Incidence ratios and resulting percentage changes were computed. Results Similar to Germany, there were significant short and long-term effects for the combined data of the four other countries (increase of 93.9%; p =0.004 and 16.7%; p =0.003). There was no indication that long-term effects are a mere reflection of an overall increase in suicide frequencies or due to increased numbers of kilometres driven by trains. Analyses on country level revealed heterogeneous results. Limitations Due to incomplete data, analyses regarding age and gender were not performed. Media coverage was only proxied by a Google Trends analysis. The study includes a small sample of European countries. Conclusions Enke's suicide in 2009 was followed by increasing train suicide numbers in Europe. Although this incident may have reinforced an existing European trend of growing railway suicides, an international copycat effect and/or an increased overall awareness about this particular suicide method appears to be one likely explanation for the changes. [ABSTRACT FROM AUTHOR]
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- 2015
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179. Personal and perceived stigmatization of depression: A comparison of data from the general population, participants of a depression congress and job placement officers in Germany.
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Dietrich, Sandra, Mergl, Roland, and Rummel-Kluge, Christine
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SOCIAL stigma , *MENTAL depression , *SENSORY perception , *COLLEGE placement services , *GENDER differences (Psychology) ,PSYCHIATRIC research - Abstract
Personal and perceived depression stigma was assessed with Griffiths and colleagues׳ Depression Stigma Scale in 1509 German adults. The sample comprised three groups of participants: attendees of a depression congress, job placement officers and a representative general population sample. In all groups, personal stigma was lower than perceived stigma. Personal stigma was significantly higher in the general population than in the placement officers, and lowest in congress attendees. Perceived stigma was lower in congress attendees than in the general population. Personal stigma was lower in women decreased with age. The finding of lower personal stigma compared to perceived stigma might reflect effects of social desirability. Those with less contact with persons with depression, i.e. job placement officers and the general population, may be less tolerant and lack understanding of depression, resulting in higher levels of personal stigma. These findings support the notion that depression campaigns should be tailor-made to address gender and age-specific differences in personal and perceived stigma. [ABSTRACT FROM AUTHOR]
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- 2014
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180. „iFightDepression" im stationären Setting: Evaluation eines internetbasierten, therapeutenbegleiteten Selbstmanagementprogramms auf einer Spezialstation für affektive Störungen.
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Schwarz, Julian, Mauche, Nicole, Oehler, Caroline, Rummel-Kluge, Christine, Hegerl, Ulrich, and Strauß, Maria
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COGNITIVE therapy - Abstract
Background: E‑mental health mainly plays a role in the outpatient treatment of patients with depressive disorders. The goal of this study was to implement and evaluate the web-based, therapist-guided self-management tool "iFightDepression" (iFD) to clarify if there is a benefit for inpatient use. Material and methods: In this study 78 inpatients with affective disorders (ICD-10 F32.0‑3, F33.0-3) or dysthymia (F34) were recruited. The intervention duration with the iFD tool went from admission until discharge, therapeutic support was granted by the ward staff. Symptom severity, intervention expectations and experience with therapy were processed in an online questionnaire before the intervention (T0) while intervention satisfaction was captured after the intervention shortly before discharge (T1) in a paper-pencil questionnaire. Results: Out of 78 participating inpatients 42 used the iFD tool at least once. Moderate to high levels of expectation regarding the iFD tool and mildly above-average level of satisfaction after the intervention were observed. Of the active users 67% indicated they would continue to use the iFD tool after discharge. The main reasons for not using the iFD tool were short duration of stay, severity of disease and lack of digital literacy. Conclusion: An implementation of the iFD tool is feasible on principle. Active users gave positive feedback concerning the intervention and most participants claimed to continue using the iFD tool after discharge; however, low usage rates among study participants (42/78, 54%) showed barriers of implementation that have to be addressed and underline the importance of adaptations regarding the use of the intervention in a clinical setting. [ABSTRACT FROM AUTHOR]
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- 2022
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181. One followed by many?—Long-term effects of a celebrity suicide on the number of suicidal acts on the German railway net
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Hegerl, Ulrich, Koburger, Nicole, Rummel-Kluge, Christine, Gravert, Christian, Walden, Martin, and Mergl, Roland
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FOLLOW-up studies (Medicine) , *SUICIDAL behavior , *FAME , *JOINT use of railroad facilities , *COPYCAT crimes , *CONFIDENCE intervals - Abstract
Abstract: Background: Following the railway suicide of Robert Enke, a famous German football goal keeper, short-term copycat effects have been found. Main aims of the present study were to analyze long-term effects of this incidence and to compare them with overall national suicide data, as well as to investigate possible “anniversary effects”. Methods: For long-term effects, the number of railway suicidal acts in the two years before and after Robert Enke''s suicide (10th November 2009) were compared. For anniversary effects, the corresponding 2-week-periods in 2009, 2010 and 2011 were analyzed. Incidence ratios with 95% confidence intervals were computed. Results: Compared to the two years before Enke''s suicide the incidence ratio of the number of railway suicidal acts in the 2-year-period following this event increased by 18.8% (95% confidence interval (CI)=11.0–27.1%; p<0.001). The median number of suicidal acts per day increased from 2 to 3 (p<0.001). This effect remains significant after excluding short-term 2-week effects of Enke''s suicide. An anniversary effect was not present. The increase of fatal railway suicides between 2007 and 2010 (25%) was significantly different from that for the total number of suicides in Germany (6.6%) (p<0.0001). Limitations: Due to missing data, analyses regarding gender were limited and regarding age not feasible. Conclusions: Long-term effects of Enke''s suicide on railway suicidal acts in Germany in the sense of copycat behavior are probable as this increase cannot be explained by corresponding changes of the total number of suicides in Germany. [Copyright &y& Elsevier]
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- 2013
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182. Depression stigma and management of suicidal callers: a cross-sectional survey of crisis hotline counselors.
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Heinz, Ines, Mergl, Roland, Hegerl, Ulrich, Rummel-Kluge, Christine, and Kohls, Elisabeth
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- 2019
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183. Promoting Help-seeking using E-technology for ADolescents with mental health problems: study protocol for a randomized controlled trial within the ProHEAD Consortium.
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Kaess, Michael, Ritter, Sabrina, Lustig, Sophia, Bauer, Stephanie, Becker, Katja, Eschenbeck, Heike, Moessner, Markus, Rummel-Kluge, Christine, Salize, Hans-Joachim, Thomasius, Rainer, Resch, Franz, Koenig, Julian, and the ProHEAD Consortium
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MENTAL health of teenagers , *HELP-seeking behavior , *ADOLESCENT psychiatry , *ADOLESCENT psychology , *MENTAL health services , *MEDICAL technology - Abstract
Background: The highest incidence and prevalence of mental health problems across the lifespan as well as the first onset of most long-term mental health conditions are reported for youths between 14 and 25 years of age. At the same time, only 25% of adolescents with mental health problems receive professional treatment. One explanation for poor treatment access in youths is their low help-seeking behavior. Barriers that can keep children and adolescents (C&A) from seeking professional help include a lack of perceived need, structural barriers, or stigma. Interventions based on e-technology might present an effective approach, overcoming these barriers by reducing stigma and providing low-threshold access with enhanced reach, ultimately facilitating help-seeking for mental health problems among youths.Methods: The study is designed as a multi-center, randomized controlled trial. In total, an estimated number of n = 1,500 C&A with mental health problems, drawn from a school-based sample of n = 15,000 pupils attending school grades 6 to 13 (≥ 12 years of age), recruited in five regions of Germany, will be randomized either to an intervention (ProHEAD online) or a control condition. C&A in the intervention group will receive online access to tailored information and individual advice on where to seek professional help for their specific needs close to their place of living, case reports of and interaction with peers, as well as the opportunity for online and telephone counseling. C&A in the control intervention will receive a recommendation to seek help and online information on where to find professional help. All participants will be asked to complete questionnaires concerning their help-seeking behavior at baseline, during the intervention (monitoring), and also at a 1 and 2 year follow-up. The primary endpoint is the number of C&A seeking conventional face-to-face professional help in the real-world setting within 1 year after their initial screening.Discussion: The trial will investigate if an Internet-based intervention can increase professional help-seeking in C&A with mental health problems. With its randomized controlled design and large-scale school-based sampling, the study aims to overcome the shortages of previous research. The intervention has the potential to narrow the treatment gap in C&A and to ultimately improve the mental health care system.Trial Registration: German Clinical Trials Register, DRKS00014685 . Registered on 7 July, 2018. [ABSTRACT FROM AUTHOR]- Published
- 2019
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184. Peer counseling in depression care: A pilot study in a psychiatric inpatient setting.
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Kohls, Elisabeth, Hug, Juliane, Stahl, Marlen, Driessen, Pia, Roemer, Christel, Wollschlaeger, Elke, Moldenhauer, Katrin, and Rummel-Kluge, Christine
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PEER counseling , *MENTAL health counselors , *PILOT projects - Abstract
Highlights • It is a pilot on acceptance and effects of peer-counseling in patients and peers. • Patients described the peer-intervention as a positive experience. • Patients especially valued the counselor's personal experiences. • A significant improvement of self-rated mood after the counseling was found. • Overall findings suggest inpatient peer-counselling as a useful, additional offer. Abstract To evaluate in a pilot study whether peer counseling is feasible and accepted for inpatients with depression. A one-to-one peer counseling intervention was implemented in an inpatient psychiatric department. Patients were invited to ask questions concerning their illness. Three trained counselors with a history of depressive episodes supervised peers. The patients evaluated the counseling and their mood. The peer counselors evaluated the counseling; in addition their depression stigma was assessed. Twenty-nine patients (F32 or F33 according to ICD-10, mean age 43 years, 58% female, hospitalized for three weeks minimum) participated. Main topics addressed were 'the patient himself' and 'treatment options, offers and services in the local area'. 94% would recommend peer counseling, 72% would like to take part again. Self-rated mood was significantly higher after than before the counseling. The findings suggest that peer counseling is a useful, additional offer for inpatients with depression as it appears to meet needs yet not addressed. Patients especially valued the counselor's personal experiences. Routine care of depression can be enhanced with peer counseling, e.g. by smoothing the transition from inpatient to outpatient treatment. Further, RCTs on peer counseling in depression should be conducted prospectively. [ABSTRACT FROM AUTHOR]
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- 2018
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185. Nutzen, Nutzung und Nebenwirkungen von digitalen Interventionen in der Behandlung von Menschen mit Depressionen
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Oehler, Caroline, Rummel-Kluge, Christine, Riedel-Heller, Steffi G., Mehnert-Theuerkauf, Anja, and Universität Leipzig
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Depression, digitale Intervention, iCBT, online Behandlung ,ddc:610 - Abstract
Die Wirksamkeit digitaler Interventionen für Depression ist mittlerweile gut belegt, wobei die beste Evidenz aus Metaanalysen stammt, die Vergleiche zu Face-to-Face Behandlungen zusammenfassen (Cuijpers et al., 2019). Studien, die Wartelisten (WL) oder Treatment-as-Usual (TAU) als Kontrollgruppe (KG) verwenden, sind kritisch zu betrachten, da bei Depression Erwartungseffekte sowie Hoffnungslosigkeit bei Randomisierung in eine KG die Effektstärken künstlich vergrößern können. Gleichzeitig sind bei WL-Kontrollen in der Langzeitbetrachtung nur noch intraindividuelle Vergleiche möglich, was die Aussagekraft begrenzt. Im Folgenden werden vier Publikationen zusammengefasst, die die Evidenz zur Wirksamkeit, Nutzung und zu potenziellen Nebenwirkungen digitaler Interventionen am Beispiel des iFightDepression Tools erweitern. Dabei werden im ersten Teil zwei Publikationen zu Daten aus einer randomisierten kontrollierten Studie (RCT) mit einer aktiven KG betrachtet (Get.Started Studie) und im zweiten Teil werden Analysen von Nutzungsdaten, sogenannten Log-Daten, beschrieben, die in der Routineversorgung in Deutschland gewonnen wurden. Die Get.Started Studie – Wirksamkeitsstudie Die Get.Started Studie ist ein RCT, bei dem sechs Wochen begleitete iFightDepression (iFD) Nutzung mit sechs Wochen begleitetem Online-Entspannungstraining (PMR) verglichen wurden. Insgesamt wurden 347 Patient:innen mit aktuell leicht- bis mittelschweren Depressionen in eine der beiden Gruppen randomisiert. Sie erhielten in fünf kurzen Telefonaten Begleitung und Unterstützung durch das Studienteam und wurden gebeten vor Beginn der Intervention, nach drei Wochen sowie nach sechs Wochen Online-Fragebögen auszufüllen. Zusätzlich wurden nach drei, sechs, und zwölf Monate Follow-Up Messungen durchgeführt. Erfasst wurde dabei die depressive Symptomatik im Selbstbericht (IDS-SR) als primäres Outcome sowie die gesundheitsbezogene Lebensqualität (SF-12) als sekundäres Outcome. Anhand dieser Studie wurden die folgenden Fragen untersucht: 1) Kann die Wirksamkeit des iFightDepression Tools im Vergleich zu einer aktiven KG gezeigt werden und bleibt ein möglicher Behandlungseffekt über einen längeren Zeitraum stabil? Mithilfe eines linearen gemischten Modells wurde der Interventionseffekt im Vergleich zur Kontrollgruppe statistisch geprüft. Insgesamt verringerten sich die Depressionssymptome, gemessen mit dem IDS-SR, in beiden Gruppen über die Zeit (t(1196.2) = -3.934; p.60). Die am häufigsten berichteten Nebenwirkungen laut INEP waren „nicht ernst genommen“ fühlen, sowie „längere Zeiten in denen es schlechter ging“. Die analysierten Freitextantworten bildeten ergänzende unerwünschte Effekte, spezifisch für das digitale Format, ab. Es wurden z.B. technische Probleme und Zeitdruck benannt. Die berichteten Nebenwirkungen wurden durch die Teilnehmer:innen meist als „leicht“ eingestuft und waren vorrübergehend. Interpretation: Auch bei multimethodaler Betrachtung ergaben sich keine Hinweise auf schwerwiegende Nebenwirkungen. Wenn auch die Häufigkeit negativer Effekte niedriger oder vergleichbar zu Face-to-Face Psychotherapie waren, können diese thematisch anders gelagert sein. Log-Daten Analysen – iFightDepression in der Regelversorgung Eine Implementierung in die Regelversorgung scheint basierend auf diesen Ergebnissen sinnvoll, birgt jedoch weitere Herausforderungen. Besonders eine häufig gering ausgeprägte Adhärenz beim Einsatz digitaler Interventionen außerhalb von Studien limitiert die potentielle Wirksamkeit solcher Interventionen. Um weitere Erkenntnisse zu Nutzung und Nutzen von iFD in der Regelversorgung zu erhalten wurden für die folgenden zwei Publikationen die automatisiert gespeicherten Log-Daten des iFD Tools analysiert. Enthalten sind die Angaben aus dem Eingangsfragebogen (minimale soziodemographische Angaben), die Summenwerte der im iFD Tool ausgefüllten PHQ-9 Symptomfragebögen sowie Logs der angeklickten Inhalte mit Zeitstempel, aus denen die Nutzungsparameter berechnet wurden. Anhand dieser Daten können naturalistische Beobachtungen über das Nutzer:innenverhalten außerhalb von Studiensettings angestellt werden, ohne dass extra Befragungen durch ein Studienteam durchgeführt werden müssen. 3) Hängt die Adhärenz in der Regelversorgung vom Beruf des Begleiters/der Begleiterin ab und kann ein Einfluss auf die Wirksamkeit gefunden werden? Betrachtet wurde ein Datensatz von 2184 TN (59.8 % weiblich, Durchschnittsalter 38.69 Jahre (SD = 13.57), die vor dem 29.06.2020 zur Nutzung von iFD eingeladen wurden. Begleitet wurden davon 512 TN (23,4 %) durch Fachärzt:innen, 838 TN (38,4 %) durch Allgemeinärzt:innen und 834 TN (38,8 %) durch psychologischen Psychotherapeut:innen. In multiplen logistischen Regressionen wurde geprüft, ob verschiedene Nutzungsparameter (z.B. Anzahl der bearbeiteten Workshops und Anzahl der Sessions) statistisch signifikant mit dem Beruf/Arbeitssetting des Begleiters/der Begleiterin assoziiert waren. Bei TN, die von psychologischen Psychotherapeut:innen begleitet wurden, lagen statistisch signifikant höhere Nutzungsparameter im Vergleich zur Begleitung durch Allgemeinärzt:innen (OR’s: 0,502-0,625, alle ps
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- 2022
186. Negative perceptions of ageing predict the onset and persistence of depression and anxiety: Findings from a prospective analysis of the Irish Longitudinal Study on Ageing (TILDA).
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Freeman, Aislinné Theresa, Santini, Ziggi Ivan, Tyrovolas, Stefanos, Rummel-Kluge, Christine, Haro, Josep Maria, and Koyanagi, Ai
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MENTAL depression , *AGING , *ANXIETY , *SOCIETAL reaction , *LOGISTIC regression analysis , *SENSORY perception - Abstract
Background: Although there is a growing literature on the adverse health outcomes related with negative ageing perceptions, studies on their association with mental disorders such as depression and anxiety are scarce. Thus, the aim of the current study was to prospectively assess the association between negative ageing perceptions and incident/persistent depression and anxiety using nationally representative data from Ireland.Methods: Data from two consecutive waves of the Irish Longitudinal Study on Ageing (TILDA) were analysed. The analytical sample consisted of 6095 adults aged ≥50 years. Validated scales for negative ageing perceptions, depression, and anxiety were used. Multivariable logistic regression analyses were used to assess the association between negative ageing perceptions at baseline and the onset and persistence of depression and anxiety at two-year follow up.Results: After adjusting for potential confounders, negative ageing perceptions at baseline predicted the new onset of depression and anxiety at follow-up. Among those with depression or anxiety at baseline, negative ageing perceptions also predicted the persistence of these conditions at follow-up.Limitations: Baseline data on negative ageing perceptions were used for the analysis and it is possible that scores could have changed over time.Conclusions: Addressing negative perceptions towards ageing by developing interventions that activate positive ageing perceptions, and target societal attitudes by means of policy change, public campaigns, and community education programmes, may shift social perceptions and reduce the burden of depression and anxiety among the elderly. [ABSTRACT FROM AUTHOR]- Published
- 2016
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187. Internet-Delivered Disease Management for Recurrent Depression: A Multicenter Randomized Controlled Trial.
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Kordy, Hans, Wolf, Markus, aulich, Kai, Bürgy, Martin, Hegerl, Ulrich, Hüsing, Johannes, Puschner, Bernd, Rummel-Kluge, Christine, Vedder, Helmut, and Backenstrass, Matthias
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MENTAL depression , *THERAPEUTICS , *DISEASE management , *INTERNET & psychology , *MENTAL depression risk factors , *COMPARATIVE studies , *INTERNET , *RESEARCH methodology , *MEDICAL cooperation , *RESEARCH , *TELEMEDICINE , *DISEASE relapse , *EVALUATION research , *RANDOMIZED controlled trials - Abstract
Background: Strategies to improve the life of patients suffering from recurrent major depression have a high relevance. This study examined the efficacy of 2 Internet-delivered augmentation strategies that aim to prolong symptom-free intervals.Methods: Efficacy was tested in a 3-arm, multicenter, open-label, evaluator-blind, randomized controlled trial. Upon discharge from inpatient mental health care, 232 adults with 3 or more major depressive episodes were randomized to 1 of 2 intervention groups (SUMMIT or SUMMIT-PERSON) or to treatment as usual (TAU) alone. Over 12 months, participants in both intervention arms received, in addition to TAU, intense monitoring via e-mail or a smartphone, including signaling of upcoming crises, assistance with personal crisis management, and facilitation of early intervention. SUMMIT-PERSON additionally offered regular expert chats. The primary outcome was 'well weeks', i.e. weeks with at most mild symptoms assessed by the Longitudinal Interval Follow-Up Evaluation, during 24 months after the index treatment.Results: SUMMIT compared to TAU reduced the time with an unwell status (OR 0.48; 95% CI 0.23-0.98) through faster transitions from unwell to well (OR 1.44; 95% CI 0.83-2.50) and slower transitions from well to unwell (OR 0.69; 95% CI 0.44-1.09). Contrary to the hypothesis, SUMMIT-PERSON was not superior to either SUMMIT (OR 0.77; 95% CI 0.38-1.56) or TAU (OR 0.62; 95% CI 0.31-1.24). The efficacy of SUMMIT was strongest 8 months after the intervention.Conclusions: The fully automated Internet-delivered augmentation strategy SUMMIT has the potential to improve TAU by reducing the lifelong burden of patients with recurrent depression. The fact that the effects wear off suggests a time-unlimited extension. [ABSTRACT FROM AUTHOR]- Published
- 2016
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188. Psychiatric patients׳ internet use corresponds to the internet use of the general public.
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Trefflich, Friederike, Kalckreuth, Sophie, Mergl, Roland, and Rummel-Kluge, Christine
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PSYCHOTHERAPY patients , *INTERNET access , *PSYCHIATRY , *THERAPEUTICS , *INTERNET users , *MENTAL health , *MENTAL illness - Abstract
The use of Internet has grown in the past number of years, including the increased application of various therapy programs for psychiatric patients which can be accessed online. Few studies investigating psychiatric patients׳ Internet use exist. Therefore, the aim of this study was to examine the number of psychiatric patients that use the Internet in comparison to the general population. Since patients with mental health disorders frequently suffer from a variety of disadvantages in society, it was evaluated whether psychiatric patients were disadvantaged particularly concerning the use and access of the Internet. Three hundred and thirty-seven patients participated in the study and completed a 29-item questionnaire. A response rate of 66% was achieved. Descriptive statistics, analysis of variance and binary logistic regression analysis were used. Out of the participants, 79.5% were Internet users. This number corresponds to the Internet use of the general population. Young patients in particular were found to use online information, using mostly search engines to seek medical information. The results show that psychiatric patients do not rank below the general population concerning the frequency of Internet use, which is especially important for accessing health related information online or participating in online programs. [ABSTRACT FROM AUTHOR]
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- 2015
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189. Olanzapine and clozapine differently affect sleep in patients with schizophrenia: Results from a double-blind, polysomnographic study and review of the literature.
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Kluge, Michael, Schacht, Alexander, Himmerich, Hubertus, Rummel-Kluge, Christine, Wehmeier, Peter M., Dalal, Mira, Hinze-Selch, Dunja, Kraus, Thomas, Dittmann, Ralf W., Pollmächer, Thomas, and Schuld, Andreas
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OLANZAPINE , *CLOZAPINE , *SCHIZOPHRENIA treatment , *POLYSOMNOGRAPHY , *BLIND experiment , *MEDICAL literature , *SCHIZOPHRENIA , *RESTLESS legs syndrome - Abstract
Abstract: Schizophrenia is associated with impaired sleep continuity. The second generation antipsychotics clozapine and olanzapine have been reported to improve sleep continuity but also to rarely induce restless legs syndrome (RLS). The aims of this randomized double-blind study were to compare the effects of clozapine and olanzapine on sleep and the occurrence of RLS. Therefore, polysomnographies were recorded and RLS symptoms were assessed in 30 patients with schizophrenia before and after 2, 4 and 6weeks of treatment with either clozapine or olanzapine. Treatment with both antipsychotics increased total sleep time, sleep period time and sleep efficiency and decreased sleep onset latency. These changes were similar in both groups, occurred during the first 2 treatment weeks and were sustained. For example, sleep efficiency increased from 83% (olanzapine) and 82% (clozapine) at baseline to 95% at week 2 and 97% at week 6 in both treatment groups. Sleep architecture was differently affected: clozapine caused a significantly stronger increase of stage 2 sleep (44%) than olanzapine (11%) but olanzapine a significantly stronger increase of REM-sleep. Olanzapine caused an 80% increase of slow wave sleep whereas clozapine caused a 6% decrease. No patient reported any of 4 RLS defining symptoms at baseline. During treatment, 1 patient of each group reported at one visit all 4 symptoms, i.e. met the diagnosis of an RLS. In conclusion, sleep continuity similarly improved and sleep architecture changed more physiologically with olanzapine. Neither of the antipsychotics induced RLS symptoms that were clinically relevant. [Copyright &y& Elsevier]
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- 2014
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190. E-Mental Health- Eine Querschnitsstudie zur Nutzung des Internets und internetbasierter Interventionen bei Patienten mit psychischen ERkrankungen
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Webelhorst, Carolin, Rummel-Kluge, Christine, Riedel-Heller, Steffi G., Schomerus, Georg, and Universität Leipzig
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E-Mental Health, Internetnutzung, internetbasierte Interventionen, Psychiatrie ,ddc:610 - Abstract
Das Internet beeinflusst unser tägliches Leben; so erweitert es auch seit Jahren das therapeutische Spektrum in der Behandlung von Patienten mit einer psychischen Erkrankung. Dennoch gilt es aufgrund von vielen unübersichtlichen Angeboten, unzureichenden rechtlichen Rahmenbedingungen sowie keiner einheitlichen Behandlungsleitlinie weiterhin einige Hürden in der Implementierung in den therapeutischen Versorgungsalltag zu überwinden. Ziel unserer Untersuchung war es, das aktuelle Internetnutzungsverhalten bezüglich der eigenen Erkrankung sowie den allgemeinen Zugang zum Internet und den aktuellen Einsatz von Selbstmanagement-Interventionen zu untersuchen, um Angebote gezielter auf die Patientengruppen anzupassen. Dabei wurden im Rahmen einer einmaligen Untersuchung zwischen Januar 2018 und Januar 2019 mittels Fragebogen, Patienten (n=301) während ihrer stationären, teilstationären oder ambulanten Behandlung in der Klinik für Psychiatrie und Psychotherapie des Universitätsklinikums Leipzig befragt. Die Mehrheit der Patienten (98 %) nutzt das Internet, wobei die meisten Patienten über ein Smartphone (90 %) und/oder ein Tablet (37 %) mit mobilem Internetzugang verfügen. Während bisher nur ein kleiner Teil (10 %) der Stichprobe bereits Erfahrungen mit internetbasierten Selbsthilfeinterventionen in der Behandlung gesammelt hat, gibt es eine weit größere Gruppe (46 %), die daran Interesse zeigt. Dieses Interesse war bei Patienten größer, die jünger waren (p=.001), ein höheres Bildungsniveau haben (p=.003) oder die das Internet zuvor als hilfreich für den Umgang mit ihrer psychischen Erkrankung empfunden haben (p=.033). Es zeigte sich zudem, dass jüngere Patienten signifikant häufiger nach Informationen über Krankheiten (p
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- 2020
191. Sleep propensity at daytime as assessed by Multiple Sleep Latency Tests (MSLT) in patients with schizophrenia increases with clozapine and olanzapine
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Kluge, Michael, Himmerich, Hubertus, Wehmeier, Peter M., Rummel-Kluge, Christine, Dalal, Mira, Hinze-Selch, Dunja, Kraus, Thomas, Dittmann, Ralf W., Pollmächer, Thomas, and Schuld, Andreas
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SCHIZOPHRENIA , *PEOPLE with schizophrenia , *CLOZAPINE , *OLANZAPINE , *SLEEP , *ANTIPSYCHOTIC agents , *DROWSINESS , *CONSCIOUS sedation - Abstract
Abstract: Sleep propensity at daytime has not been investigated in untreated patients with schizophrenia. Furthermore, while the antipsychotics clozapine and olanzapine are considered to frequently cause ‘sleepiness’ or ‘sedation’, this has not been objectified yet. Therefore, 30 patients with schizophrenia were included in this randomized, double-blind study. Sleep propensity was assessed before and after 2, 4 and 6weeks of treatment with either clozapine or olanzapine using a Multiple Sleep Latency Test (MSLT); in the MSLT, sleep latencies of 5 nap opportunities of 20min during daytime are averaged. In addition, the number of sleep onsets was recorded. Mean sleep latency in untreated schizophrenic patients was 16.2±0.8min at baseline. Both antipsychotics induced an increase of sleep propensity as indicated by a shortened sleep latency and more sleep onsets during the treatment period as compared to baseline. These effects were strongest in the morning. Four patients receiving clozapine and 3 patients receiving olanzapine reported subjective sleepiness, in all but one commencing in the first treatment week and persisting until study end. While the mean sleep latency during treatment was significantly shorter in these patients (12.3±0.8min) than in those without subjective sleepiness (14.9±0.7min), a short sleep latency was not necessarily associated with subjective sleepiness. In conclusion, mean sleep latency was >36% longer (i.e. sleep propensity was lower) in untreated patients with schizophrenia than in healthy subjects previously consistently reported. Furthermore, clozapine and olanzapine increased sleep propensity in schizophrenic patients. A minority of patients reported subjective sleepiness. [Copyright &y& Elsevier]
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- 2012
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192. Das Internet als erkrankungsbezogene Informationsquelle und soziales Medium für PatientInnen mit psychischen Erkrankungen
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Kalckreuth, Sophie, Rummel-Kluge, Christine, Hegerl, Ulrich, Bauer, Stephanie, and Universität Leipzig
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Internet, Psychiatry, Availability, Information seeking, Social media, Internet based interventions ,ddc:610 ,Internet, Psychiatrie, Verfügbarkeit, Informationssuche, Soziale Medien, Internet-basierte Interventioen - Abstract
Hintergrund: Das Internet spielt heutzutage in Gesundheitsfragen eine große Rolle. Fast alle Internetnutzer greifen im Zusammenhang mit Erkrankungen auf Onlineangebote zurück, um beispielsweise Informationen über Krankheitsbilder oder Medikamente zu suchen. Speziell für den Bereich seelische Gesundheit verfügt das Internet darüber hinaus noch über weiteres Potential: Mit der Entwicklung von Online-Programmen wurden in den letzten Jahren neue Behandlungsmöglichkeiten für psychische Erkrankungen geschaffen. Diese verwenden die multimedialen Möglichkeiten des Internets zu therapeutischen Zwecken und konnten in zahlreichen Studien vielversprechende Ergebnisse zeigen. Für die Nutzung der Programme sind dabei regelmäßiger Internetzugang und Routine im Umgang mit unterschiedlichen Internetfunktionen notwendig - insbesondere mit sozialen Medien. Ausmaß und Muster der Internetnutzung psychiatrischer Patienten im Zusammenhang mit ihrer Erkrankung sind jedoch bislang kaum erforscht. Ziel der vorliegenden Arbeit ist es, das erkrankungsbezogene Internetnutzungsverhalten dieser Patientengruppe zu erfassen und zu analysieren. Methode: Patienten aller Stationen und Ambulanzen der Klinik und Poliklinik für Psychiatrie und Psychotherapie des Universitätsklinikums Leipzig wurden mit Hilfe eines Fragebogens zu ihrem Internetnutzungsverhalten befragt. Anhand von 29 Items wurden soziodemographische Daten, das allgemeine Internetnutzungsverhalten und die erkrankungsbezogene Internetnutzung (mental-health related Internet use) erfasst. Die Datenanalyse beinhaltete die Bestimmung von Häufigkeiten und Gruppenvergleiche. Hierzu wurde vornehmlich der Chi-Quadrat-Test verwendet. Ergebnisse: 337 Patienten nahmen an der Studie teil. 79.5% von ihnen waren Internetnutzer und wurden in Abhängigkeit von ihrer wöchentlichen Nutzungsdauer in die Subgruppen Wenig-, Mittel- und Vielnutzer eingeteilt. Soziale Medien wurden von weniger als der Hälfte der Nutzer verwendet: Soziale Netzwerke (47.8%), Foren (19.4%), Chats (18.7%), Blogs (12.3%). 70.9% nutzten das Internet im Kontext ihrer psychischen Erkrankung. Hierbei handelte es sich um folgende Inhalte: Informationen zu psychischen Erkrankungen (57.8%), Informationen zu Medikamenten (43.7%), Suche nach Psychiatern bzw. psychiatrischen Kliniken (38.8%), Erfahrungsaustausch mit anderen Betroffenen (19.8%), Nutzung von Foren mit Psychiatern (17.2%). Unterschiede im Nutzungsmuster zwischen Wenig-, Mittel- und Vielnutzern waren statistisch signifikant für alle Formen sozialer Medien (p
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- 2015
193. Charakteristika der allgemeinen Internetnutzung psychiatrischer Patienten
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Trefflich, Friederike, Rummel-Kluge, Christine, Kersting, Anette, Himmerich, Hubertus, and Universität Leipzig
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Internetnutzung psychiatrischer Patienten ,ddc:610 ,internet use psychiatric patients - Abstract
Die Arbeit befasst sich mit der Internetnutzung von psychiatrischen Patienten. Das Angebot an Therapien für Patienten mit psychiatrischen Erkrankungen steigt seit Jahren. Auch die Menge an Informationen, welche vor allem online zu bekommen sind, wird immer größer. Allerdings gibt es nur wenige Informationen zur Internetnutzung von psychiatrischen Patienten im Vergleich zur Gesamtbevölkerung. Sind psychiatrische Patienten bezüglich Zugang zum Internet und Nutzung von Internetinformationen und -therapien benachteiligt?
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- 2015
194. An examination of sociodemographic and clinical factors influencing help-seeking attitudes and behaviors among adolescents with mental health problems.
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Cavelti M, Ruppen NA, Sele S, Moessner M, Bauer S, Becker K, Krämer J, Eschenbeck H, Rummel-Kluge C, Thomasius R, Diestelkamp S, Gillé V, Baldofski S, Koenig J, and Kaess M
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This study investigated sociodemographic and clinical factors influencing help-seeking attitudes and behavior among adolescents with mental health problems. As part of the ProHEAD ("Promoting Help-seeking using E-technology for ADolescents") consortium a school-based, online assessment of sociodemographic information, psychopathology, risk-taking and self-harming behavior, help-seeking attitudes and behavior, and barriers to help-seeking was conducted in adolescents aged ≥ 12 years recruited from randomly selected schools in five regions of Germany. Linear regression analyses with the LMG formula were performed to explore predictors of help-seeking attitudes and behavior and assess their relative importance. Nine thousand five hundred and nine participants (95.5%) completed the online assessment (mean age: 15.1 years, 58.6% female). In total, 1606 participants (16.9%) showed relevant mental health problems (e.g., depressive and eating disorder symptoms, alcohol problems, and thoughts of self-harming behavior). Among them, 895 (55.7%) reported having sought help (lifetime), with higher rates for informal (n = 842, 52.4%) compared to professional (n = 380, 23.7%) sources. High help-seeking propensity emerged as the most important factor contributing to professional help-seeking, followed by elevated levels of psychopathology and perceived barriers, with sociodemographic factors being less impactful. Psychopathological severity also outweighed sociodemographic factors in predicting negative help-seeking attitudes. These findings indicate that attitudes towards seeking professional help, perceived barriers, and psychopathology severity critically influence limited adolescent help-seeking behavior. This emphasizes the need for initiatives that promote help-seeking, reduce negative attitudes, and address structural barriers in adolescent mental health care., (© 2024. The Author(s).)
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- 2024
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195. The Impact of Video-Based Microinterventions on Attitudes Toward Mental Health and Help Seeking in Youth: Web-Based Randomized Controlled Trial.
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Lemmer D, Moessner M, Arnaud N, Baumeister H, Mutter A, Klemm SL, König E, Plener P, Rummel-Kluge C, Thomasius R, Kaess M, and Bauer S
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- Adolescent, Adult, Female, Humans, Male, Young Adult, Help-Seeking Behavior, Mental Disorders psychology, Mental Disorders therapy, Mental Health, Patient Acceptance of Health Care psychology, Patient Acceptance of Health Care statistics & numerical data, Video Recording, Internet
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Background: Mental health (MH) problems in youth are prevalent, burdening, and frequently persistent. Despite the existence of effective treatment, the uptake of professional help is low, particularly due to attitudinal barriers., Objective: This study evaluated the effectiveness and acceptability of 2 video-based microinterventions aimed at reducing barriers to MH treatment and increasing the likelihood of seeking professional help in young people., Methods: This study was entirely web based and open access. The interventions addressed 5 MH problems: generalized anxiety disorder, depression, bulimia, nonsuicidal self-injury, and problematic alcohol use. Intervention 1 aimed to destigmatize and improve MH literacy, whereas intervention 2 aimed to induce positive outcome expectancies regarding professional help seeking. Of the 2435 participants who commenced the study, a final sample of 1394 (57.25%) participants aged 14 to 29 years with complete data and sufficient durations of stay on the video pages were randomized in a fully automated manner to 1 of the 5 MH problems and 1 of 3 conditions (control, intervention 1, and intervention 2) in a permuted block design. After the presentation of a video vignette, no further videos were shown to the control group, whereas a second, short intervention video was presented to the intervention 1 and 2 groups. Intervention effects on self-reported potential professional help seeking (primary outcome), stigma, and attitudes toward help seeking were examined using analyses of covariance across and within the 5 MH problems. Furthermore, we assessed video acceptability., Results: No significant group effects on potential professional help seeking were found in the total sample (F
2,1385 =0.99; P=.37). However, the groups differed significantly with regard to stigma outcomes and the likelihood of seeking informal help (F2,1385 =3.75; P=.02). Furthermore, separate analyses indicated substantial differences in intervention effects among the 5 MH problems., Conclusions: Interventions to promote help seeking for MH problems may require disorder-specific approaches. The study results can inform future research and public health campaigns addressing adolescents and young adults., Trial Registration: German Clinical Trials Register DRKS00023110; https://drks.de/search/de/trial/DRKS00023110., (©Diana Lemmer, Markus Moessner, Nicolas Arnaud, Harald Baumeister, Agnes Mutter, Sarah-Lena Klemm, Elisa König, Paul Plener, Christine Rummel-Kluge, Rainer Thomasius, Michael Kaess, Stephanie Bauer. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 24.04.2024.)- Published
- 2024
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196. Linguistic Variables and Gender Differences Within a Messenger-Based Psychosocial Chat Counseling Service for Children and Adolescents: Cross-Sectional Study.
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Efe Z, Baldofski S, Kohls E, Eckert M, Saee S, Thomas J, Wundrack R, and Rummel-Kluge C
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Background: Text messaging is widely used by young people for communicating and seeking mental health support through chat-based helplines. However, written communication lacks nonverbal cues, and language usage is an important source of information about a person's mental health state and is known to be a marker for psychopathology., Objective: The aim of the study was to investigate language usage, and its gender differences and associations with the presence of psychiatric symptoms within a chat counseling service for adolescents and young adults., Methods: For this study, the anonymized chat content of a German messenger-based psychosocial chat counseling service for children and adolescents ("krisenchat") between May 2020 and July 2021 was analyzed. In total, 661,131 messages from 6962 users were evaluated using Linguistic Inquiry and Word Count, considering the following linguistic variables: first-person singular and plural pronouns, negations, positive and negative emotion words, insight words, and causation words. Descriptive analyses were performed, and gender differences of those variables were evaluated. Finally, a binary logistic regression analysis examined the predictive value of linguistic variables on the presence of psychiatric symptoms., Results: Across all analyzed chats, first-person singular pronouns were used most frequently (965,542/8,328,309, 11.6%), followed by positive emotion words (408,087/8,328,309, 4.9%), insight words (341,460/8,328,309, 4.1%), negations (316,475/8,328,309, 3.8%), negative emotion words (266,505/8,328,309, 3.2%), causation words (241,520/8,328,309, 2.9%), and first-person plural pronouns (499,698/8,328,309, 0.6%). Female users and users identifying as diverse used significantly more first-person singular pronouns and insight words than male users (both P<.001). Negations were significantly more used by female users than male users or users identifying as diverse (P=.007). Similar findings were noted for negative emotion words (P=.01). The regression model of predicting psychiatric symptoms by linguistic variables was significant and indicated that increased use of first-person singular pronouns (odds ratio [OR] 1.05), negations (OR 1.11), and negative emotion words (OR 1.15) was positively associated with the presence of psychiatric symptoms, whereas increased use of first-person plural pronouns (OR 0.39) and causation words (OR 0.90) was negatively associated with the presence of psychiatric symptoms. Suicidality, self-harm, and depression showed the most significant correlations with linguistic variables., Conclusions: This study highlights the importance of examining linguistic features in chat counseling contexts. By integrating psycholinguistic findings into counseling practice, counselors may better understand users' psychological processes and provide more targeted support. For instance, certain linguistic features, such as high use of first-person singular pronouns, negations, or negative emotion words, may indicate the presence of psychiatric symptoms, particularly among female users and users identifying as diverse. Further research is needed to provide an in-depth look into language processes within chat counseling services., (©Zeki Efe, Sabrina Baldofski, Elisabeth Kohls, Melanie Eckert, Shadi Saee, Julia Thomas, Richard Wundrack, Christine Rummel-Kluge. Originally published in JMIR Formative Research (https://formative.jmir.org), 12.01.2024.)
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- 2024
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197. Reasons for non-participation of children and adolescents in a large-scale school-based mental health project.
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Baldofski S, Klemm SL, Kohls E, Mueller SME, Bauer S, Becker K, Diestelkamp S, Eschenbeck H, Hiery A, Kaess M, Koenig J, Lehner L, Moessner M, Thomasius R, and Rummel-Kluge C
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- Child, Humans, Adolescent, Cross-Sectional Studies, Germany, Parents, Mental Health, Schools
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Background: Non-participation in mental health studies is an under-explored but very important topic. Investigating reasons for non-participation holds promise for the planning of future study designs and recruitment strategies. This study aimed at investigating reasons for children and adolescents (C&A) not participating in a school-based mental health research project., Methods: Data collection took place within the school-based recruitment of a large-scale multi-site project ("ProHEAD-Promoting Help-seeking using E-technology for Adolescents") in Germany. Participants were N = 534 C&A aged ≥ 12 years attending secondary schools. The present cross-sectional study analyzed anonymous survey data of C&A who themselves or whose parents, respectively, did not provide written consent to participate in the mental health research project. The questionnaire consisted of 14 items covering potential reasons for non-participation, and four free text fields. Besides descriptive statistics, free text field answers were analyzed using qualitative content analysis., Results: Students indicated an average of M = 2.94 ( SD = 1.75) reasons for their non-participation in the project. In the descriptive analysis of indicated items, the three most frequently reported reasons for non-participation included students reporting to not be concerned by the topic "mental health" ( n = 290, 54.3%), not having returned the consent form to the teacher ( n = 175, 32.8%), and not having time for participation ( n = 149, 27.9%). In the qualitative content analysis, the most frequently assigned categories were organizational reasons ( n = 216, 57.1%), general disinterest in study participation ( n = 139, 36.8%), and personal attitudes toward the topic "mental health" ( n = 84, 22.2%), such as not being concerned with the topic "mental health" ( n = 23, 6.1%) or being too concerned with the topic "mental health" ( n = 16, 4.2%)., Conclusion: The study provides unique insights into reasons for C&A and their caregivers not participating in a large federally funded mental health research project. The results suggest that in order to increase participation rates, stigma should be reduced, parents as well as teachers should be involved where possible, and the use of incentives might be helpful. The study highlights the importance of assessing reasons for non-participation, especially in online intervention studies on mental health., Competing Interests: KB has received honorary from Georg Thieme Publisher during the last 5 years outside and independent of the submitted work. CR-K received lecture honoraria from Recordati and Servier outside and independent of the submitted work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Baldofski, Klemm, Kohls, Mueller, Bauer, Becker, Diestelkamp, Eschenbeck, Hiery, Kaess, Koenig, Lehner, Moessner, Thomasius and Rummel-Kluge.)
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- 2024
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198. Corrigendum: Acceptability, feasibility, and user satisfaction of a virtual reality relaxation intervention in a psychiatric outpatient setting during the COVID-19 pandemic.
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Humbert A, Kohls E, Baldofski S, Epple C, and Rummel-Kluge C
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[This corrects the article DOI: 10.3389/fpsyt.2023.1271702.]., (Copyright © 2024 Humbert, Kohls, Baldofski, Epple and Rummel-Kluge.)
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- 2024
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199. Acceptability, feasibility, and user satisfaction of a virtual reality relaxation intervention in a psychiatric outpatient setting during the COVID-19 pandemic.
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Humbert A, Kohls E, Baldofski S, Epple C, and Rummel-Kluge C
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Background: The COVID-19 pandemic was particularly difficult for individuals with mental disorders. Due to governmental restrictions, face-to-face offers for psychiatric outpatients like therapies, psychoeducational groups or relaxation courses were limited. Virtual reality (VR) might be a new possibility to support these patients by providing them with a home-based relaxation tool., Objective: The aim of this study was to evaluate the acceptability, feasibility, and user satisfaction of a supportive therapy-accompanying, relaxation VR intervention in psychiatric outpatients during the COVID-19 pandemic in Germany., Methods: The four-weeks VR intervention consisted of regular watching of relaxing videos in the participants' home environment. Sociodemographics, feasibility (frequency of use, user-friendliness), satisfaction (Client Satisfaction Questionnaire-8), depressive symptoms (Patient Health Questionnaire-9), quality of life (abbreviated World Health Organization Quality of Life assessment), and credibility and expectancy (Credibility Expectancy Questionnaire-8) were measured in an intention-to-treat (ITT) analysis and a per-protocol (PP) analysis of completers., Results: In total, N = 40 patients participated in the study. Most of the participants in the ITT analysis ( n = 30, 75.0%) used the VR device three or 4 weeks. A majority of the N = 29 completers (PP: n = 18, 62.1%) used it all 4 weeks. Most participants used the device two or more times a week (ITT: n = 30, 83.3%; PP: n = 26, 89.7%) and described the user-friendliness as rather or very easy (ITT: n = 33, 91.7%; PP: n = 26, 89.7%). User satisfaction was high (ITT: 19.42, SD = 4.08; PP: M = 20.00, SD = 4.19) and did not correlate with participants' sex or age (all p < 0.05). Depressive symptoms and psychological quality of life improved significantly from pre-to post-intervention (ITT and PP, all p < 0.05). Higher pre-intervention credibility significantly correlated with a better outcome of satisfaction (ITT and PP), depressive symptoms, physical, psychological, and social quality of life (PP; all p < 0.05)., Conclusion: A supportive therapy-accompanying VR relaxation intervention is feasible and acceptable in a psychiatric outpatient setting. Due to the high satisfaction and user-friendliness, VR can be an easy to implement relaxation tool to support psychiatric outpatients., Clinical Trial Registration: https://clinicaltrials.gov/, DRKS00027911., Competing Interests: CE is the managing director of Lab E GmbH. CR-K received lecture honoraria from Recordati and Servier outside and independent of the submitted work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision., (Copyright © 2023 Humbert, Kohls, Baldofski, Epple and Rummel-Kluge.)
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- 2023
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200. Acceptability and Feasibility of Online Support Groups for Mental Health Promotion in Brazilian Graduate Students During the COVID-19 Pandemic: Longitudinal Observational Study.
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Prado ADS, Kohls E, Baldofski S, Rummel-Kluge C, and Freitas JL
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Background: The outbreak of the COVID-19 pandemic in 2020 aggravated already existing difficulties and added new challenges for students. Owing to the gap between needed and available psychological services, group interventions may offer a helpful strategy for student mental health promotion., Objective: This study aimed to investigate the acceptability and feasibility of a 4-week online support group program designed for mental health promotion tailored to graduate students at a Brazilian public university in the context of the COVID-19 pandemic (May 2022 to June 2022)., Methods: Participants in the program took part in online support groups based on a pilot group facilitated by a trained clinical psychologist. Self-administered, standardized web-based questionnaires were assessed at the baseline (T0; before the intervention), postintervention (T2), and follow-up (T3; after 4-6 weeks) time points. We measured sociodemographic variables, treatment credibility and expectancy (Credibility and Expectancy Questionnaire), satisfaction (Client Satisfaction Questionnaire), negative effects of the intervention (Negative Effects Questionnaire), depressive symptoms (Patient Health Questionnaire-9 [PHQ-9]), and participants' quality of life (abbreviated World Health Organization Quality of Life assessment). A 9-answer option questionnaire and open-ended questions also assessed the group's perceived positive and negative outcomes., Results: The total sample comprised 32 participants. Most (23/32, 72%) were doctoral students. Credibility and expectancy scores were high. Participants' satisfaction (Client Satisfaction Questionnaire) with the program was high at the postintervention (T2) and follow-up (T3) evaluations (T2: mean 28.66, SD 3.02; T3: mean 27.91, SD 3.02). Most participants reported that they could learn from other participants' experiences (T2: 29/32, 91%; T3: 27/32, 84%) and felt encouraged to take better care of themselves (T2: 22/32, 69%; T3: 24/32, 75%). None of the participants reported that they had no benefits from the program. The PHQ-9 scores showed mild to moderate depressive symptoms (mean 9.59, SD 6.34), whereas the answers of 9% (3/32) of the participants to the PHQ-9 item 9 indicated suicidality at baseline (T0). Finally, the 4 domains of quality of life (physical: P=.01; psychological: P=.004; social: P=.02; and environmental: P<.001) showed a slight and statistically significant improvement at the postintervention evaluation (T0: mean 57.03, SD 15.39 to 59.64, SD 17.21; T2: mean 64.32, SD 11.97 to 68.75, SD 8.87)., Conclusions: Online support groups for the mental health promotion of graduate students are feasible and can be especially useful for universities with students allocated to different cities. They are also satisfactory and may positively influence participants' quality of life. Therefore, they can be considered a helpful mental health promotion strategy in the educational context. Further studies could evaluate these (or similar) programs under nonpandemic circumstances., (©Aneliana da Silva Prado, Elisabeth Kohls, Sabrina Baldofski, Christine Rummel-Kluge, Joanneliese de Lucas Freitas. Originally published in JMIR Formative Research (https://formative.jmir.org), 13.10.2023.)
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- 2023
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