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162. Cadmium Highlights Common and Specific Responses of Two Freshwater Sentinel Species, Dreissena polymorpha and Dreissena rostriformis bugensis

Author

Florence Bultelle, Aimie Le Saux, Elise David, Arnaud Tanguy, Simon Devin, Stéphanie Olivier, Agnès Poret, Philippe Chan, Fanny Louis, Laurence Delahaut, Sandrine Pain-Devin, Romain Péden, David Vaudry, Frank Le Foll, and Béatrice Rocher

Subjects
quagga mussel, zebra mussel, proteoforms, stress, biomonitoring, Microbiology, QR1-502
Abstract

Zebra mussel (ZM), Dreissena polymorpha, commonly used as a sentinel species in freshwater biomonitoring, is now in competition for habitat with quagga mussel (QM), Dreissena rostriformis bugensis. This raises the question of the quagga mussel’s use in environmental survey. To better characterise QM response to stress compared with ZM, both species were exposed to cadmium (100 µg·L−1), a classic pollutant, for 7 days under controlled conditions. The gill proteomes were analysed using two-dimensional electrophoresis coupled with mass spectrometry. For ZM, 81 out of 88 proteoforms of variable abundance were identified using mass spectrometry, and for QM, 105 out of 134. Interestingly, the proteomic response amplitude varied drastically, with 5.6% of proteoforms of variable abundance (DAPs) in ZM versus 9.4% in QM. QM also exhibited greater cadmium accumulation. Only 12 common DAPs were observed. Several short proteoforms were detected, suggesting proteolysis. Functional analysis is consistent with the pleiotropic effects of the toxic metal ion cadmium, with alterations in sulphur and glutathione metabolisms, cellular calcium signalling, cytoskeletal dynamics, energy production, chaperone activation, and membrane events with numerous proteins involved in trafficking and endocytosis/exocytosis processes. Beyond common responses, the sister species display distinct reactions, with cellular response to stress being the main category involved in ZM as opposed to calcium and cytoskeleton alterations in QM. Moreover, QM exhibited greater evidence of proteolysis and cell death. Overall, these results suggest that QM has a weaker stress response capacity than ZM.

Published
2024
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163. The Early Data Release of the Dark Energy Spectroscopic Instrument

Author

DESI Collaboration, A. G. Adame, J. Aguilar, S. Ahlen, S. Alam, G. Aldering, D. M. Alexander, R. Alfarsy, C. Allende Prieto, M. Alvarez, O. Alves, A. Anand, F. Andrade-Oliveira, E. Armengaud, J. Asorey, S. Avila, A. Aviles, S. Bailey, A. Balaguera-Antolínez, O. Ballester, C. Baltay, A. Bault, J. Bautista, J. Behera, S. F. Beltran, S. BenZvi, L. Beraldo e Silva, J. R. Bermejo-Climent, A. Berti, R. Besuner, F. Beutler, D. Bianchi, C. Blake, R. Blum, A. S. Bolton, S. Brieden, A. Brodzeller, D. Brooks, Z. Brown, E. Buckley-Geer, E. Burtin, L. Cabayol-Garcia, Z. Cai, R. Canning, L. Cardiel-Sas, A. Carnero Rosell, F. J. Castander, J. L. Cervantes-Cota, S. Chabanier, E. Chaussidon, J. Chaves-Montero, S. Chen, X. Chen, C. Chuang, T. Claybaugh, S. Cole, A. P. Cooper, A. Cuceu, T. M. Davis, K. Dawson, R. de Belsunce, R. de la Cruz, A. de la Macorra, J. Della Costa, A. de Mattia, R. Demina, U. Demirbozan, J. DeRose, A. Dey, B. Dey, G. Dhungana, J. Ding, Z. Ding, P. Doel, R. Doshi, K. Douglass, A. Edge, S. Eftekharzadeh, D. J. Eisenstein, A. Elliott, J. Ereza, S. Escoffier, P. Fagrelius, X. Fan, K. Fanning, V. A. Fawcett, S. Ferraro, B. Flaugher, A. Font-Ribera, J. E. Forero-Romero, D. Forero-Sánchez, C. S. Frenk, B. T. Gänsicke, L. Á. García, J. García-Bellido, C. Garcia-Quintero, L. H. Garrison, H. Gil-Marín, J. Golden-Marx, S. Gontcho A Gontcho, A. X. Gonzalez-Morales, V. Gonzalez-Perez, C. Gordon, O. Graur, D. Green, D. Gruen, J. Guy, B. Hadzhiyska, C. Hahn, J. J. Han, M. M. S Hanif, H. K. Herrera-Alcantar, K. Honscheid, J. Hou, C. Howlett, D. Huterer, V. Iršič, M. Ishak, A. Jacques, A. Jana, L. Jiang, J. Jimenez, Y. P. Jing, S. Joudaki, R. Joyce, E. Jullo, S. Juneau, N. G. Karaçaylı, T. Karim, R. Kehoe, S. Kent, A. Khederlarian, S. Kim, D. Kirkby, T. Kisner, F. Kitaura, N. Kizhuprakkat, J. Kneib, S. E. Koposov, A. Kovács, A. Kremin, A. Krolewski, B. L’Huillier, O. Lahav, A. Lambert, C. Lamman, T.-W. Lan, M. Landriau, D. Lang, J. U. Lange, J. Lasker, A. Leauthaud, L. Le Guillou, M. E. Levi, T. S. Li, E. Linder, A. Lyons, C. Magneville, M. Manera, C. J. Manser, D. Margala, P. Martini, P. McDonald, G. E. Medina, L. Medina-Varela, A. Meisner, J. Mena-Fernández, J. Meneses-Rizo, M. Mezcua, R. Miquel, P. Montero-Camacho, J. Moon, S. Moore, J. Moustakas, E. Mueller, J. Mundet, A. Muñoz-Gutiérrez, A. D. Myers, S. Nadathur, L. Napolitano, R. Neveux, J. A. Newman, J. Nie, R. Nikutta, G. Niz, P. Norberg, H. E. Noriega, E. Paillas, N. Palanque-Delabrouille, A. Palmese, Z. Pan, D. Parkinson, S. Penmetsa, W. J. Percival, A. Pérez-Fernández, I. Pérez-Ràfols, M. Pieri, C. Poppett, A. Porredon, S. Pothier, F. Prada, R. Pucha, A. Raichoor, C. Ramírez-Pérez, S. Ramirez-Solano, M. Rashkovetskyi, C. Ravoux, A. Rocher, C. Rockosi, A. J. Ross, G. Rossi, R. Ruggeri, V. Ruhlmann-Kleider, C. G. Sabiu, K. Said, A. Saintonge, L. Samushia, E. Sanchez, C. Saulder, E. Schaan, E. F. Schlafly, D. Schlegel, D. Scholte, M. Schubnell, H. Seo, A. Shafieloo, R. Sharples, W. Sheu, J. Silber, F. Sinigaglia, M. Siudek, Z. Slepian, A. Smith, M. T. Soumagnac, D. Sprayberry, L. Stephey, J. Suárez-Pérez, Z. Sun, T. Tan, G. Tarlé, R. Tojeiro, L. A. Ureña-López, R. Vaisakh, D. Valcin, F. Valdes, M. Valluri, M. Vargas-Magaña, A. Variu, L. Verde, M. Walther, B. Wang, M. S. Wang, B. A. Weaver, N. Weaverdyck, R. H. Wechsler, M. White, Y. Xie, J. Yang, C. Yèche, J. Yu, S. Yuan, H. Zhang, Z. Zhang, C. Zhao, Z. Zheng, R. Zhou, Z. Zhou, H. Zou, S. Zou, and Y. Zu

Subjects
Astronomy data reduction, Observational cosmology, Astronomy databases, Astronomy data analysis, Astronomy software, Surveys, Astronomy, QB1-991
Abstract

The Dark Energy Spectroscopic Instrument (DESI) completed its 5 month Survey Validation in 2021 May. Spectra of stellar and extragalactic targets from Survey Validation constitute the first major data sample from the DESI survey. This paper describes the public release of those spectra, the catalogs of derived properties, and the intermediate data products. In total, the public release includes good-quality spectral information from 466,447 objects targeted as part of the Milky Way Survey, 428,758 as part of the Bright Galaxy Survey, 227,318 as part of the Luminous Red Galaxy sample, 437,664 as part of the Emission Line Galaxy sample, and 76,079 as part of the Quasar sample. In addition, the release includes spectral information from 137,148 objects that expand the scope beyond the primary samples as part of a series of secondary programs. Here, we describe the spectral data, data quality, data products, Large-Scale Structure science catalogs, access to the data, and references that provide relevant background to using these spectra.

Published
2024
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164. Validation of the Scientific Program for the Dark Energy Spectroscopic Instrument

Author

DESI Collaboration, A. G. Adame, J. Aguilar, S. Ahlen, S. Alam, G. Aldering, D. M. Alexander, R. Alfarsy, C. Allende Prieto, M. Alvarez, O. Alves, A. Anand, F. Andrade-Oliveira, E. Armengaud, J. Asorey, S. Avila, A. Aviles, S. Bailey, A. Balaguera-Antolínez, O. Ballester, C. Baltay, A. Bault, J. Bautista, J. Behera, S. F. Beltran, S. BenZvi, L. Beraldo e Silva, J. R. Bermejo-Climent, A. Berti, R. Besuner, F. Beutler, D. Bianchi, C. Blake, R. Blum, A. S. Bolton, S. Brieden, A. Brodzeller, D. Brooks, Z. Brown, E. Buckley-Geer, E. Burtin, L. Cabayol-Garcia, Z. Cai, R. Canning, L. Cardiel-Sas, A. Carnero Rosell, F. J. Castander, J. L. Cervantes-Cota, S. Chabanier, E. Chaussidon, J. Chaves-Montero, S. Chen, X. Chen, C. Chuang, T. Claybaugh, S. Cole, A. P. Cooper, A. Cuceu, T. M. Davis, K. Dawson, R. de Belsunce, R. de la Cruz, A. de la Macorra, A. de Mattia, R. Demina, U. Demirbozan, J. DeRose, A. Dey, B. Dey, G. Dhungana, J. Ding, Z. Ding, P. Doel, R. Doshi, K. Douglass, A. Edge, S. Eftekharzadeh, D. J. Eisenstein, A. Elliott, S. Escoffier, P. Fagrelius, X. Fan, K. Fanning, V. A. Fawcett, S. Ferraro, J. Ereza, B. Flaugher, A. Font-Ribera, D. Forero-Sánchez, J. E. Forero-Romero, C. S. Frenk, B. T. Gänsicke, L. Á. García, J. García-Bellido, C. Garcia-Quintero, L. H. Garrison, H. Gil-Marín, J. Golden-Marx, S. Gontcho A Gontcho, A. X. Gonzalez-Morales, V. Gonzalez-Perez, C. Gordon, O. Graur, D. Green, D. Gruen, J. Guy, B. Hadzhiyska, C. Hahn, J. J. Han, M. M. S Hanif, H. K. Herrera-Alcantar, K. Honscheid, J. Hou, C. Howlett, D. Huterer, V. Iršič, M. Ishak, A. Jana, L. Jiang, J. Jimenez, Y. P. Jing, S. Joudaki, E. Jullo, R. Joyce, S. Juneau, N. Kizhuprakkat, N. G. Karaçaylı, T. Karim, R. Kehoe, S. Kent, A. Khederlarian, S. Kim, D. Kirkby, T. Kisner, F. Kitaura, J. Kneib, S. E. Koposov, A. Kovács, A. Kremin, A. Krolewski, B. L’Huillier, O. Lahav, A. Lambert, C. Lamman, T.-W. Lan, M. Landriau, D. Lang, J. U. Lange, J. Lasker, L. Le Guillou, A. Leauthaud, M. E. Levi, T. S. Li, E. Linder, A. Lyons, C. Magneville, M. Manera, C. J. Manser, D. Margala, P. Martini, P. McDonald, G. E. Medina, L. Medina-Varela, A. Meisner, J. Mena-Fernández, J. Meneses-Rizo, M. Mezcua, R. Miquel, P. Montero-Camacho, J. Moon, S. Moore, J. Moustakas, E. Mueller, J. Mundet, A. Muñoz-Gutiérrez, A. D. Myers, S. Nadathur, L. Napolitano, R. Neveux, J. A. Newman, J. Nie, G. Niz, P. Norberg, H. E. Noriega, E. Paillas, N. Palanque-Delabrouille, A. Palmese, P. Zhiwei, D. Parkinson, S. Penmetsa, W. J. Percival, A. Pérez-Fernández, I. Pérez-Ràfols, M. Pieri, C. Poppett, A. Porredon, F. Prada, R. Pucha, A. Raichoor, C. Ramírez-Pérez, S. Ramirez-Solano, M. Rashkovetskyi, C. Ravoux, A. Rocher, C. Rockosi, A. J. Ross, G. Rossi, R. Ruggeri, V. Ruhlmann-Kleider, C. G. Sabiu, K. Said, A. Saintonge, L. Samushia, E. Sanchez, C. Saulder, E. Schaan, E. F. Schlafly, D. Schlegel, D. Scholte, M. Schubnell, H. Seo, A. Shafieloo, R. Sharples, W. Sheu, J. Silber, F. Sinigaglia, M. Siudek, Z. Slepian, A. Smith, D. Sprayberry, L. Stephey, J. Suárez-Pérez, Z. Sun, T. Tan, G. Tarlé, R. Tojeiro, L. A. Ureña-López, R. Vaisakh, D. Valcin, F. Valdes, M. Valluri, M. Vargas-Magaña, A. Variu, L. Verde, M. Walther, B. Wang, M. S. Wang, B. A. Weaver, N. Weaverdyck, R. H. Wechsler, M. White, Y. Xie, J. Yang, C. Yèche, J. Yu, S. Yuan, H. Zhang, Z. Zhang, C. Zhao, Z. Zheng, R. Zhou, Z. Zhou, H. Zou, S. Zou, and Y. Zu

Subjects
Cosmology, Redshift surveys, Astronomy, QB1-991
Abstract

The Dark Energy Spectroscopic Instrument (DESI) was designed to conduct a survey covering 14,000 deg ^2 over 5 yr to constrain the cosmic expansion history through precise measurements of baryon acoustic oscillations (BAO). The scientific program for DESI was evaluated during a 5 month survey validation (SV) campaign before beginning full operations. This program produced deep spectra of tens of thousands of objects from each of the stellar Milky Way Survey (MWS), Bright Galaxy Survey (BGS), luminous red galaxy (LRG), emission line galaxy (ELG), and quasar target classes. These SV spectra were used to optimize redshift distributions, characterize exposure times, determine calibration procedures, and assess observational overheads for the 5 yr program. In this paper, we present the final target selection algorithms, redshift distributions, and projected cosmology constraints resulting from those studies. We also present a One-Percent Survey conducted at the conclusion of SV covering 140 deg ^2 using the final target selection algorithms with exposures of a depth typical of the main survey. The SV indicates that DESI will be able to complete the full 14,000 deg ^2 program with spectroscopically confirmed targets from the MWS, BGS, LRG, ELG, and quasar programs with total sample sizes of 7.2, 13.8, 7.46, 15.7, and 2.87 million, respectively. These samples will allow exploration of the Milky Way halo, clustering on all scales, and BAO measurements with a statistical precision of 0.28% over the redshift interval z < 1.1, 0.39% over the redshift interval 1.1 < z < 1.9, and 0.46% over the redshift interval 1.9 < z < 3.5.

Published
2024
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165. Effectiveness Assessment of Cyber-Physical Systems

Author

Rocher, Gérald, Tigli, Jean-Yves, Lavirotte, Stéphane, and Thanh, Nhan Le

Subjects
Computer Science - Artificial Intelligence
Abstract

By achieving their purposes through interactions with the physical world, Cyber-Physical Systems (CPS) pose new challenges in terms of dependability. Indeed, the evolution of the physical systems they control with transducers can be affected by surrounding physical processes over which they have no control and which may potentially hamper the achievement of their purposes. While it is illusory to hope for a comprehensive model of the physical environment at design time to anticipate and remove faults that may occur once these systems are deployed, it becomes necessary to evaluate their degree of effectiveness in vivo. In this paper, the degree of effectiveness is formally defined and generalized in the context of the measure theory. The measure is developed in the context of the Transferable Belief Model (TBM), an elaboration on the Dempster-Shafer Theory (DST) of evidence so as to handle epistemic and aleatory uncertainties respectively pertaining the users' expectations and the natural variability of the physical environment. The TBM is used in conjunction with the Input/Output Hidden Markov Modeling framework (we denote by Ev-IOHMM) to specify the expected evolution of the physical system controlled by the CPS and the tolerances towards uncertainties. The measure of effectiveness is then obtained from the forward algorithm, leveraging the conflict entailed by the successive combinations of the beliefs obtained from observations of the physical system and the beliefs corresponding to its expected evolution. The proposed approach is applied to autonomous vehicles and show how the degree of effectiveness can be used for bench-marking their controller relative to the highway code speed limitations and passengers' well-being constraints, both modeled through an Ev-IOHMM., Comment: Preprint submitted to International Journal of Approximate Reasoning

Published
2019

168. Recommandations conjointes du réseau National ENDOCAN-COMETE, de l’Association francophone de chirurgie endocrinienne et de la Société française d’urologie pour la prise en charge du carcinome corticosurrénalien

Author

Libé, Rossella, Haissaguerre, Magalie, Renaudin, Karine, Faron, Matthieu, Decaussin-Petrucci, Myriam, Deschamps, Fréderic, Gimenez-Roqueplo, Anne-Paule, Mirallie, Eric, Murez, Thibaut, Pattou, François, Rocher, Laurence, Taïeb, David, Savoie, Pierre Henri, Tabarin, Antoine, Bertherat, Jérôme, Baudin, Eric, and de la Fouchardière, Christelle

Published
2023
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169. Free and kerogen‐bound biomarkers from late Tonian sedimentary rocks record abundant eukaryotes in mid‐Neoproterozoic marine communities

Author

Zumberge, J Alex, Rocher, Don, and Love, Gordon D

Subjects
Life Below Water, Biomarkers, Cholestanes, Eukaryota, Geologic Sediments, Photosynthesis, eukaryotes, HyPy, lipid biomarkers, Neoproterozoic, steranes, Geochemistry, Geology, Ecology, Geochemistry & Geophysics
Abstract

Lipid biomarker assemblages preserved within the bitumen and kerogen phases of sedimentary rocks from the ca. 780-729 Ma Chuar and Visingsö Groups facilitate paleoenvironmental reconstructions and reveal fundamental aspects of emerging mid-Neoproterozoic marine communities. The Chuar and Visingsö Groups were deposited offshore of two distinct paleocontinents (Laurentia and Baltica, respectively) during the Tonian Period, and the rock samples used had not undergone excessive metamorphism. The major polycyclic alkane biomarkers detected in the rock bitumens and kerogen hydropyrolysates consist of tricyclic terpanes, hopanes, methylhopanes, and steranes. Major features of the biomarker assemblages include detectable and significant contribution from eukaryotes, encompassing the first robust occurrences of kerogen-bound regular steranes from Tonian rocks, including 21-norcholestane, 27-norcholestane, cholestane, ergostane, and cryostane, along with a novel unidentified C30 sterane series from our least thermally mature Chuar Group samples. Appreciable values for the sterane/hopane (S/H) ratio are found for both the free and kerogen-bound biomarker pools for both the Chuar Group rocks (S/H between 0.09 and 1.26) and the Visingsö Group samples (S/H between 0.03 and 0.37). The more organic-rich rock samples generally yield higher S/H ratios than for organic-lean substrates, which suggests a marine nutrient control on eukaryotic abundance relative to bacteria. A C27 sterane (cholestane) predominance among total C26 -C30 steranes is a common feature found for all samples investigated, with lower amounts of C28 steranes (ergostane and crysotane) also present. No traces of known ancient C30 sterane compounds; including 24-isopropylcholestanes, 24-n-propylcholestanes, or 26-methylstigmastanes, are detectable in any of these pre-Sturtian rocks. These biomarker characteristics support the view that the Tonian Period was a key interval in the history of life on our planet since it marked the transition from a bacterially dominated marine biosphere to an ocean system which became progressively enriched with eukaryotes. The eukaryotic source organisms likely encompassed photosynthetic primary producers, marking a rise in red algae, and consumers in a revamped trophic structure predating the Sturtian glaciation.

Published
2020

172. Explainable Electrocardiogram Analysis with Wave Decomposition: Application to Myocardial Infarction Detection

Author

Yang, Yingyu, Rocher, Marie, Moceri, Pamela, Sermesant, Maxime, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Camara, Oscar, editor, Puyol-Antón, Esther, editor, Qin, Chen, editor, Sermesant, Maxime, editor, Suinesiaputra, Avan, editor, Wang, Shuo, editor, and Young, Alistair, editor

Published
2022
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173. Semantic Inferences Towards Smart IoT-Based Systems Actuation Conflicts Management

Author

Rocher, Gérald, Tigli, Jean-Yves, Lavirotte, Stéphane, Rannenberg, Kai, Editor-in-Chief, Soares Barbosa, Luís, Editorial Board Member, Goedicke, Michael, Editorial Board Member, Tatnall, Arthur, Editorial Board Member, Neuhold, Erich J., Editorial Board Member, Stiller, Burkhard, Editorial Board Member, Tröltzsch, Fredi, Editorial Board Member, Pries-Heje, Jan, Editorial Board Member, Kreps, David, Editorial Board Member, Reis, Ricardo, Editorial Board Member, Furnell, Steven, Editorial Board Member, Mercier-Laurent, Eunika, Editorial Board Member, Winckler, Marco, Editorial Board Member, Malaka, Rainer, Editorial Board Member, Camarinha-Matos, Luis M., editor, Ribeiro, Luis, editor, and Strous, Leon, editor

Published
2022
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174. Low-Cost Sensor to Detect the Blood in Urine

Author

Viciano-Tudela, Sandra, Rocher, Javier, Basterrechea, Daniel A., Parra, Lorena, Lloret, Jaime, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Balas, Valentina E., editor, and Ezziyyani, Mostafa, editor

Published
2022
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175. Species and functional responses of ants to inter-row tillage and vegetation in organic Mediterranean vineyards

Author

Léo Rocher, Romane Blaya, Chloé Blaise, Armin Bischoff, and Olivier Blight

Subjects
Ants, Agroecology, Community ecology, Functional traits, Ecology, QH540-549.5
Abstract

Ants are arthropods providing crucial ecosystem services such as soil structuring, nutrient cycling, seed dispersal and pest predation. Thus, their abundance and diversity need to be considered in approaches to improve sustainability of land use such as Mediterranean viticulture. In our study, we tested whether (1) inter-row vegetation and the absence of tillage increase the species richness and/or functional diversity of ants in vineyards and (2) ground cover vegetation drives ant species composition. We included 23 Mediterranean organic vineyards in our analyses and distinguished three types of inter-row management: all inter-rows tilled, half of the inter-rows tilled, and all inter-rows are untilled and covered by vegetation. The occurrence of ant species was analysed in six pitfall traps per vineyard. Around each trap, the floristic composition of inter-row vegetation was analysed in 2 × 2 m² plots. We found that inter-row tillage significantly affected ant species richness, being higher in partially than in fully tilled vineyards whereas untilled vineyards were not different from the other tillage types. Grass cover and the perennial/annual rate were positively correlated with ant species richness. Ant functional diversity and the frequency of most predatory ants were not correlated neither with plant functional groups nor with tillage type. In conclusion, ant communities benefit from inter-row vegetation and/or absence of soil disturbance but partial inter-row tillage of vineyards may be tolerated and even benefit several species. In particular, grasses and perennial plant species favour ants in our system and need to be considered in inter-row sowing.

Published
2022
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176. The behaviour of metals in deep fluids of NE Iceland

Author

Marion Saby, Vincent van Hinsberg, Daniele L. Pinti, Kim Berlo, Bjarni Gautason, Ásgerður Sigurðardóttir, Kevin Brown, and Océane Rocher

Subjects
Medicine, Science
Abstract

Abstract In this contribution, we present some of the first data on the elemental signature of deep crustal fluids in a basalt-hosted, low-chloride magmatic-hydrothermal system. Down-hole fluid samples (850–1600 m) from wells in the Theistareykir and Krafla geothermal fields in the Northern Volcanic Zone of Iceland were combined with well-head samples of condensed vapor, cuttings of altered rock, and fresh basalt (being some of the first concentration data for volatile and semi-volatile elements (Sb, Tl, Bi, Cd and As) for this area of Iceland). Results show that the deep fluids are relatively enriched in base metals and (semi)-volatile metals (in particular Te, Hg, Re and Tl) compared to local basalt. We interpret this enrichment in volatile metals to reflect a significant element input from magma degassing. Boiling of this deep fluid results in a well-head fluid composition that is significantly depleted in most elements. This well-head fluid has a distinct elemental signature, including a depletion in Sb that is mirrored in the altered rocks, and a depletion in the base metals that shows their selective sequestration in scale minerals, likely sulphides. As expected, the element content and patterns in surface fluids can thus not be interpreted to directly reflect that of the deep reservoir fluid. The behaviour of elements in Theistareykir and Krafla fluids is consistent, and largely agrees with similar data obtained for the Reykjanes geothermal system in SW Iceland. We therefore posit that our results are representative for this geological setting and indicate a significant magmatic degassing cation input to deep fluids, variably modified by water–rock interaction.

Published
2022
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177. Re-examining the relationship between mindfulness facets, attentional control, and dispositional reinforcement sensitivity

Author

Andrew R. du Rocher

Subjects
mindfulness, reinforcement sensitivity, bis, bas, fffs, attentional control, Psychology, BF1-990
Abstract

This study re-examines the relationships between the five mindfulness facets of observing, describing, acting-with-awareness, non-judging, and non-reactivity, and the affective personality measures inspired by the revised Reinforcement Sensitivity Theory (rRST). The rRST measures assess behavioural inhibition sensitivity, fight-flight-freeze sensitivity, and the behavioural approach sensitivity components of reward interest, goal-drive-persistence, reward reactivity, and impulsivity. Research has suggested that relationships exist between specific mindfulness facets and specific rRST constructs. However, some non-significant relationships were reported, possibly due to the small sample used. Also included in the analyses is (self-reported) attentional control, a variable that has not been accounted for in rRST and mindfulness research, but is inter-correlated with mindfulness and anxiety. In a sample of 641 participants, behavioral inhibition sensitivity shared a negative relationship with the describing, acting with awareness, non-judging, and non-reactivity components of mindfulness, and the impulsivity component of behavioural approach sensitivity shared a negative relationship with the acting with awareness facet of mindfulness. This is consistent with previous research. Attentional control shared a positive relationship with the describing, acting with awareness. and non-judging facets of mindfulness. In conclusion, specific reinforcement sensitivity personality constructs and attentional control relate to specific mindfulness components. Trait mindfulness and/or the efficacy of mindfulness interventions could be affected by variations in reinforcement sensitivity and attentional control ability.

Published
2022
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178. Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia

Author

Jérôme Salles, Audrey Chanet, Christelle Guillet, Anouk MM. Vaes, Elske M. Brouwer-Brolsma, Christophe Rocher, Christophe Giraudet, Véronique Patrac, Emmanuelle Meugnier, Christophe Montaurier, Philippe Denis, Olivier Le Bacquer, Adeline Blot, Marion Jourdan, Yvette Luiking, Matthew Furber, Miriam Van Dijk, Nicolas Tardif, Y. Yves Boirie, and Stéphane Walrand

Subjects
Biology (General), QH301-705.5
Abstract

Vitamin D has an impact on mitochondrial biogenesis and oxidative activity in skeletal muscle both in vitro and in vivo, and vitamin D supplementation in older people may improve muscle mass and strength.

Published
2022
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182. Bathing Activities and Microbiological River Water Quality in the Paris Area: A Long-Term Perspective

Author

Mouchel, Jean-Marie, Lucas, Françoise S., Moulin, Laurent, Wurtzer, Sébastien, Euzen, Agathe, Haghe, Jean-Paul, Rocher, Vincent, Azimi, Sam, Servais, Pierre, Hutzinger, Otto, Founding Editor, Barceló, Damià, Series Editor, Kostianoy, Andrey G., Series Editor, de Boer, Jacob, Editorial Board Member, Garrigues, Philippe, Editorial Board Member, Gu, Ji-Dong, Editorial Board Member, Jones, Kevin C., Editorial Board Member, Knepper, Thomas P., Editorial Board Member, Negm, Abdelazim M., Editorial Board Member, Newton, Alice, Editorial Board Member, Nghiem, Duc Long, Editorial Board Member, Garcia-Segura, Sergi, Editorial Board Member, Flipo, Nicolas, editor, Labadie, Pierre, editor, Lestel, Laurence, editor, Alligant, S., With Contri. by, Alliot, F., With Contri. by, Anglade, J., With Contri. by, Ansart, P., With Contri. by, Ayrault, S., With Contri. by, Azimi, S., With Contri. by, Baratelli, F., With Contri. by, Barjhoux, I., With Contri. by, Barles, S., With Contri. by, Beaudoin, N., With Contri. by, Belliard, J., With Contri. by, Benedetti, M. F., With Contri. by, Berthe, T., With Contri. by, Beslagic, S., With Contri. by, Bigot-Clivot, A., With Contri. by, Billen, G., With Contri. by, Blanchard, M., With Contri. by, Blanchoud, H., With Contri. by, Boé, J., With Contri. by, Bonnard, M., With Contri. by, Bonnet, R., With Contri. by, Boust, D., With Contri. by, Bressy, A., With Contri. by, Briand, C., With Contri. by, Brignon, J.-M., With Contri. by, Budzinski, H., With Contri. by, Carré, C., With Contri. by, Chevreuil, M., With Contri. by, Chong, N., With Contri. by, Collard, F., With Contri. by, Cordier, M.-A., With Contri. by, Dedourge-Geffard, O., With Contri. by, Derenne, S., With Contri. by, Deroubaix, J.-F., With Contri. by, Desportes, A., With Contri. by, Dris, R., With Contri. by, Eschbach, D., With Contri. by, Esculier, F., With Contri. by, Euzen, A., With Contri. by, Gallois, N., With Contri. by, Flipo, N., With Contri. by, Garnier, J., With Contri. by, Gasperi, J., With Contri. by, Gateuille, D., With Contri. by, Geffard, A., With Contri. by, Gelabert, A., With Contri. by, Gob, F., With Contri. by, Goffin, A., With Contri. by, Goutte, A., With Contri. by, Groleau, A., With Contri. by, Guigon, E., With Contri. by, Guillon, S., With Contri. by, Guo, Y., With Contri. by, Habets, F., With Contri. by, Haghe, J.-P., With Contri. by, Labadie, P., With Contri. by, Labarthe, B., With Contri. by, Le Noë, J., With Contri. by, Le Pichon, C., With Contri. by, Léonard, J., With Contri. by, Lestel, L., With Contri. by, Lorgeoux, C., With Contri. by, Louis, Y., With Contri. by, Lucas, F. S., With Contri. by, Marescaux, A., With Contri. by, Mary, B., With Contri. by, Matar, Z., With Contri. by, Meybeck, M., With Contri. by, Mignolet, C., With Contri. by, Moilleron, R., With Contri. by, Mouchel, J.-M., With Contri. by, Moulin, L., With Contri. by, Muresan, B., With Contri. by, Nguyen, P. T., With Contri. by, Oziol, L., With Contri. by, Palos-Ladeiro, M., With Contri. by, Parlanti, E., With Contri. by, Passy, P., With Contri. by, Petit, F., With Contri. by, Puech, T., With Contri. by, Queyrel, W., With Contri. by, Raimonet, M., With Contri. by, Riviére, A., With Contri. by, Rocher, V., With Contri. by, Schott, C., With Contri. by, Schuite, J., With Contri. by, Seguin, L., With Contri. by, Servais, P., With Contri. by, Silvestre, M., With Contri. by, Soares-Pereira, C., With Contri. by, Tales, E., With Contri. by, Tallec, G., With Contri. by, Tassin, B., With Contri. by, Teil, M.-J., With Contri. by, Théry, S., With Contri. by, Thevenot, D., With Contri. by, Thieu, V., With Contri. by, Tournebize, J., With Contri. by, Tramoy, R., With Contri. by, Treilles, R., With Contri. by, Varrault, G., With Contri. by, Viennot, P., With Contri. by, Vilmin, L., With Contri. by, and Wurtzer, S., With Contri. by

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2021
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183. Ecological Functioning of the Seine River: From Long-Term Modelling Approaches to High-Frequency Data Analysis

Author

Garnier, J., Marescaux, A., Guillon, S., Vilmin, L., Rocher, V., Billen, G., Thieu, V., Silvestre, M., Passy, P., Raimonet, M., Groleau, A., Théry, S., Tallec, G., Flipo, N., Hutzinger, Otto, Founding Editor, Barceló, Damià, Series Editor, Kostianoy, Andrey G., Series Editor, de Boer, Jacob, Editorial Board Member, Garrigues, Philippe, Editorial Board Member, Gu, Ji-Dong, Editorial Board Member, Jones, Kevin C., Editorial Board Member, Knepper, Thomas P., Editorial Board Member, Negm, Abdelazim M., Editorial Board Member, Newton, Alice, Editorial Board Member, Nghiem, Duc Long, Editorial Board Member, Garcia-Segura, Sergi, Editorial Board Member, Flipo, Nicolas, editor, Labadie, Pierre, editor, Lestel, Laurence, editor, Alligant, S., With Contri. by, Alliot, F., With Contri. by, Anglade, J., With Contri. by, Ansart, P., With Contri. by, Ayrault, S., With Contri. by, Azimi, S., With Contri. by, Baratelli, F., With Contri. by, Barjhoux, I., With Contri. by, Barles, S., With Contri. by, Beaudoin, N., With Contri. by, Belliard, J., With Contri. by, Benedetti, M. F., With Contri. by, Berthe, T., With Contri. by, Beslagic, S., With Contri. by, Bigot-Clivot, A., With Contri. by, Billen, G., With Contri. by, Blanchard, M., With Contri. by, Blanchoud, H., With Contri. by, Boé, J., With Contri. by, Bonnard, M., With Contri. by, Bonnet, R., With Contri. by, Boust, D., With Contri. by, Bressy, A., With Contri. by, Briand, C., With Contri. by, Brignon, J.-M., With Contri. by, Budzinski, H., With Contri. by, Carré, C., With Contri. by, Chevreuil, M., With Contri. by, Chong, N., With Contri. by, Collard, F., With Contri. by, Cordier, M.-A., With Contri. by, Dedourge-Geffard, O., With Contri. by, Derenne, S., With Contri. by, Deroubaix, J.-F., With Contri. by, Desportes, A., With Contri. by, Dris, R., With Contri. by, Eschbach, D., With Contri. by, Esculier, F., With Contri. by, Euzen, A., With Contri. by, Gallois, N., With Contri. by, Flipo, N., With Contri. by, Garnier, J., With Contri. by, Gasperi, J., With Contri. by, Gateuille, D., With Contri. by, Geffard, A., With Contri. by, Gelabert, A., With Contri. by, Gob, F., With Contri. by, Goffin, A., With Contri. by, Goutte, A., With Contri. by, Groleau, A., With Contri. by, Guigon, E., With Contri. by, Guillon, S., With Contri. by, Guo, Y., With Contri. by, Habets, F., With Contri. by, Haghe, J.-P., With Contri. by, Labadie, P., With Contri. by, Labarthe, B., With Contri. by, Le Noë, J., With Contri. by, Le Pichon, C., With Contri. by, Léonard, J., With Contri. by, Lestel, L., With Contri. by, Lorgeoux, C., With Contri. by, Louis, Y., With Contri. by, Lucas, F. S., With Contri. by, Marescaux, A., With Contri. by, Mary, B., With Contri. by, Matar, Z., With Contri. by, Meybeck, M., With Contri. by, Mignolet, C., With Contri. by, Moilleron, R., With Contri. by, Mouchel, J.-M., With Contri. by, Moulin, L., With Contri. by, Muresan, B., With Contri. by, Nguyen, P. T., With Contri. by, Oziol, L., With Contri. by, Palos-Ladeiro, M., With Contri. by, Parlanti, E., With Contri. by, Passy, P., With Contri. by, Petit, F., With Contri. by, Puech, T., With Contri. by, Queyrel, W., With Contri. by, Raimonet, M., With Contri. by, Riviére, A., With Contri. by, Rocher, V., With Contri. by, Schott, C., With Contri. by, Schuite, J., With Contri. by, Seguin, L., With Contri. by, Servais, P., With Contri. by, Silvestre, M., With Contri. by, Soares-Pereira, C., With Contri. by, Tales, E., With Contri. by, Tallec, G., With Contri. by, Tassin, B., With Contri. by, Teil, M.-J., With Contri. by, Théry, S., With Contri. by, Thevenot, D., With Contri. by, Thieu, V., With Contri. by, Tournebize, J., With Contri. by, Tramoy, R., With Contri. by, Treilles, R., With Contri. by, Varrault, G., With Contri. by, Viennot, P., With Contri. by, Vilmin, L., With Contri. by, and Wurtzer, S., With Contri. by

Published
2021
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184. Aquatic Organic Matter in the Seine Basin: Sources, Spatio-Temporal Variability, Impact of Urban Discharges and Influence on Micro-pollutant Speciation

Author

Varrault, G., Parlanti, E., Matar, Z., Garnier, J., Nguyen, P. T., Derenne, S., Rocher, V., Muresan, B., Louis, Y., Soares-Pereira, C., Goffin, A., Benedetti, M. F., Bressy, A., Gelabert, A., Guo, Y., Cordier, M.-A., Hutzinger, Otto, Founding Editor, Barceló, Damià, Series Editor, Kostianoy, Andrey G., Series Editor, de Boer, Jacob, Editorial Board Member, Garrigues, Philippe, Editorial Board Member, Gu, Ji-Dong, Editorial Board Member, Jones, Kevin C., Editorial Board Member, Knepper, Thomas P., Editorial Board Member, Negm, Abdelazim M., Editorial Board Member, Newton, Alice, Editorial Board Member, Nghiem, Duc Long, Editorial Board Member, Garcia-Segura, Sergi, Editorial Board Member, Flipo, Nicolas, editor, Labadie, Pierre, editor, Lestel, Laurence, editor, Alligant, S., With Contri. by, Alliot, F., With Contri. by, Anglade, J., With Contri. by, Ansart, P., With Contri. by, Ayrault, S., With Contri. by, Azimi, S., With Contri. by, Baratelli, F., With Contri. by, Barjhoux, I., With Contri. by, Barles, S., With Contri. by, Beaudoin, N., With Contri. by, Belliard, J., With Contri. by, Benedetti, M. F., With Contri. by, Berthe, T., With Contri. by, Beslagic, S., With Contri. by, Bigot-Clivot, A., With Contri. by, Billen, G., With Contri. by, Blanchard, M., With Contri. by, Blanchoud, H., With Contri. by, Boé, J., With Contri. by, Bonnard, M., With Contri. by, Bonnet, R., With Contri. by, Boust, D., With Contri. by, Bressy, A., With Contri. by, Briand, C., With Contri. by, Brignon, J.-M., With Contri. by, Budzinski, H., With Contri. by, Carré, C., With Contri. by, Chevreuil, M., With Contri. by, Chong, N., With Contri. by, Collard, F., With Contri. by, Cordier, M.-A., With Contri. by, Dedourge-Geffard, O., With Contri. by, Derenne, S., With Contri. by, Deroubaix, J.-F., With Contri. by, Desportes, A., With Contri. by, Dris, R., With Contri. by, Eschbach, D., With Contri. by, Esculier, F., With Contri. by, Euzen, A., With Contri. by, Gallois, N., With Contri. by, Flipo, N., With Contri. by, Garnier, J., With Contri. by, Gasperi, J., With Contri. by, Gateuille, D., With Contri. by, Geffard, A., With Contri. by, Gelabert, A., With Contri. by, Gob, F., With Contri. by, Goffin, A., With Contri. by, Goutte, A., With Contri. by, Groleau, A., With Contri. by, Guigon, E., With Contri. by, Guillon, S., With Contri. by, Guo, Y., With Contri. by, Habets, F., With Contri. by, Haghe, J.-P., With Contri. by, Labadie, P., With Contri. by, Labarthe, B., With Contri. by, Le Noë, J., With Contri. by, Le Pichon, C., With Contri. by, Léonard, J., With Contri. by, Lestel, L., With Contri. by, Lorgeoux, C., With Contri. by, Louis, Y., With Contri. by, Lucas, F. S., With Contri. by, Marescaux, A., With Contri. by, Mary, B., With Contri. by, Matar, Z., With Contri. by, Meybeck, M., With Contri. by, Mignolet, C., With Contri. by, Moilleron, R., With Contri. by, Mouchel, J.-M., With Contri. by, Moulin, L., With Contri. by, Muresan, B., With Contri. by, Nguyen, P. T., With Contri. by, Oziol, L., With Contri. by, Palos-Ladeiro, M., With Contri. by, Parlanti, E., With Contri. by, Passy, P., With Contri. by, Petit, F., With Contri. by, Puech, T., With Contri. by, Queyrel, W., With Contri. by, Raimonet, M., With Contri. by, Riviére, A., With Contri. by, Rocher, V., With Contri. by, Schott, C., With Contri. by, Schuite, J., With Contri. by, Seguin, L., With Contri. by, Servais, P., With Contri. by, Silvestre, M., With Contri. by, Soares-Pereira, C., With Contri. by, Tales, E., With Contri. by, Tallec, G., With Contri. by, Tassin, B., With Contri. by, Teil, M.-J., With Contri. by, Théry, S., With Contri. by, Thevenot, D., With Contri. by, Thieu, V., With Contri. by, Tournebize, J., With Contri. by, Tramoy, R., With Contri. by, Treilles, R., With Contri. by, Varrault, G., With Contri. by, Viennot, P., With Contri. by, Vilmin, L., With Contri. by, and Wurtzer, S., With Contri. by

Published
2021
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185. Contaminants of Emerging Concern in the Seine River Basin: Overview of Recent Research

Author

Labadie, Pierre, Alligant, Soline, Berthe, Thierry, Budzinski, Hélène, Bigot-Clivot, Aurélie, Collard, France, Dris, Rachid, Gasperi, Johnny, Guigon, Elodie, Petit, Fabienne, Rocher, Vincent, Tassin, Bruno, Tramoy, Romain, Treilles, Robin, Hutzinger, Otto, Founding Editor, Barceló, Damià, Series Editor, Kostianoy, Andrey G., Series Editor, de Boer, Jacob, Editorial Board Member, Garrigues, Philippe, Editorial Board Member, Gu, Ji-Dong, Editorial Board Member, Jones, Kevin C., Editorial Board Member, Knepper, Thomas P., Editorial Board Member, Negm, Abdelazim M., Editorial Board Member, Newton, Alice, Editorial Board Member, Nghiem, Duc Long, Editorial Board Member, Garcia-Segura, Sergi, Editorial Board Member, Flipo, Nicolas, editor, Labadie, Pierre, editor, Lestel, Laurence, editor, Alligant, S., With Contri. by, Alliot, F., With Contri. by, Anglade, J., With Contri. by, Ansart, P., With Contri. by, Ayrault, S., With Contri. by, Azimi, S., With Contri. by, Baratelli, F., With Contri. by, Barjhoux, I., With Contri. by, Barles, S., With Contri. by, Beaudoin, N., With Contri. by, Belliard, J., With Contri. by, Benedetti, M. F., With Contri. by, Berthe, T., With Contri. by, Beslagic, S., With Contri. by, Bigot-Clivot, A., With Contri. by, Billen, G., With Contri. by, Blanchard, M., With Contri. by, Blanchoud, H., With Contri. by, Boé, J., With Contri. by, Bonnard, M., With Contri. by, Bonnet, R., With Contri. by, Boust, D., With Contri. by, Bressy, A., With Contri. by, Briand, C., With Contri. by, Brignon, J.-M., With Contri. by, Budzinski, H., With Contri. by, Carré, C., With Contri. by, Chevreuil, M., With Contri. by, Chong, N., With Contri. by, Collard, F., With Contri. by, Cordier, M.-A., With Contri. by, Dedourge-Geffard, O., With Contri. by, Derenne, S., With Contri. by, Deroubaix, J.-F., With Contri. by, Desportes, A., With Contri. by, Dris, R., With Contri. by, Eschbach, D., With Contri. by, Esculier, F., With Contri. by, Euzen, A., With Contri. by, Gallois, N., With Contri. by, Flipo, N., With Contri. by, Garnier, J., With Contri. by, Gasperi, J., With Contri. by, Gateuille, D., With Contri. by, Geffard, A., With Contri. by, Gelabert, A., With Contri. by, Gob, F., With Contri. by, Goffin, A., With Contri. by, Goutte, A., With Contri. by, Groleau, A., With Contri. by, Guigon, E., With Contri. by, Guillon, S., With Contri. by, Guo, Y., With Contri. by, Habets, F., With Contri. by, Haghe, J.-P., With Contri. by, Labadie, P., With Contri. by, Labarthe, B., With Contri. by, Le Noë, J., With Contri. by, Le Pichon, C., With Contri. by, Léonard, J., With Contri. by, Lestel, L., With Contri. by, Lorgeoux, C., With Contri. by, Louis, Y., With Contri. by, Lucas, F. S., With Contri. by, Marescaux, A., With Contri. by, Mary, B., With Contri. by, Matar, Z., With Contri. by, Meybeck, M., With Contri. by, Mignolet, C., With Contri. by, Moilleron, R., With Contri. by, Mouchel, J.-M., With Contri. by, Moulin, L., With Contri. by, Muresan, B., With Contri. by, Nguyen, P. T., With Contri. by, Oziol, L., With Contri. by, Palos-Ladeiro, M., With Contri. by, Parlanti, E., With Contri. by, Passy, P., With Contri. by, Petit, F., With Contri. by, Puech, T., With Contri. by, Queyrel, W., With Contri. by, Raimonet, M., With Contri. by, Riviére, A., With Contri. by, Rocher, V., With Contri. by, Schott, C., With Contri. by, Schuite, J., With Contri. by, Seguin, L., With Contri. by, Servais, P., With Contri. by, Silvestre, M., With Contri. by, Soares-Pereira, C., With Contri. by, Tales, E., With Contri. by, Tallec, G., With Contri. by, Tassin, B., With Contri. by, Teil, M.-J., With Contri. by, Théry, S., With Contri. by, Thevenot, D., With Contri. by, Thieu, V., With Contri. by, Tournebize, J., With Contri. by, Tramoy, R., With Contri. by, Treilles, R., With Contri. by, Varrault, G., With Contri. by, Viennot, P., With Contri. by, Vilmin, L., With Contri. by, and Wurtzer, S., With Contri. by

Published
2021
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186. Mass Balance of PAHs at the Scale of the Seine River Basin

Author

Gateuille, D., Gasperi, J., Briand, C., Guigon, E., Alliot, F., Blanchard, M., Teil, M.-J., Chevreuil, M., Rocher, V., Azimi, S., Thevenot, D., Moilleron, R., Brignon, J.-M., Meybeck, M., Mouchel, J.-M., Hutzinger, Otto, Founding Editor, Barceló, Damià, Series Editor, Kostianoy, Andrey G., Series Editor, de Boer, Jacob, Editorial Board Member, Garrigues, Philippe, Editorial Board Member, Gu, Ji-Dong, Editorial Board Member, Jones, Kevin C., Editorial Board Member, Knepper, Thomas P., Editorial Board Member, Negm, Abdelazim M., Editorial Board Member, Newton, Alice, Editorial Board Member, Nghiem, Duc Long, Editorial Board Member, Garcia-Segura, Sergi, Editorial Board Member, Flipo, Nicolas, editor, Labadie, Pierre, editor, Lestel, Laurence, editor, Alligant, S., With Contri. by, Alliot, F., With Contri. by, Anglade, J., With Contri. by, Ansart, P., With Contri. by, Ayrault, S., With Contri. by, Azimi, S., With Contri. by, Baratelli, F., With Contri. by, Barjhoux, I., With Contri. by, Barles, S., With Contri. by, Beaudoin, N., With Contri. by, Belliard, J., With Contri. by, Benedetti, M. F., With Contri. by, Berthe, T., With Contri. by, Beslagic, S., With Contri. by, Bigot-Clivot, A., With Contri. by, Billen, G., With Contri. by, Blanchard, M., With Contri. by, Blanchoud, H., With Contri. by, Boé, J., With Contri. by, Bonnard, M., With Contri. by, Bonnet, R., With Contri. by, Boust, D., With Contri. by, Bressy, A., With Contri. by, Briand, C., With Contri. by, Brignon, J.-M., With Contri. by, Budzinski, H., With Contri. by, Carré, C., With Contri. by, Chevreuil, M., With Contri. by, Chong, N., With Contri. by, Collard, F., With Contri. by, Cordier, M.-A., With Contri. by, Dedourge-Geffard, O., With Contri. by, Derenne, S., With Contri. by, Deroubaix, J.-F., With Contri. by, Desportes, A., With Contri. by, Dris, R., With Contri. by, Eschbach, D., With Contri. by, Esculier, F., With Contri. by, Euzen, A., With Contri. by, Gallois, N., With Contri. by, Flipo, N., With Contri. by, Garnier, J., With Contri. by, Gasperi, J., With Contri. by, Gateuille, D., With Contri. by, Geffard, A., With Contri. by, Gelabert, A., With Contri. by, Gob, F., With Contri. by, Goffin, A., With Contri. by, Goutte, A., With Contri. by, Groleau, A., With Contri. by, Guigon, E., With Contri. by, Guillon, S., With Contri. by, Guo, Y., With Contri. by, Habets, F., With Contri. by, Haghe, J.-P., With Contri. by, Labadie, P., With Contri. by, Labarthe, B., With Contri. by, Le Noë, J., With Contri. by, Le Pichon, C., With Contri. by, Léonard, J., With Contri. by, Lestel, L., With Contri. by, Lorgeoux, C., With Contri. by, Louis, Y., With Contri. by, Lucas, F. S., With Contri. by, Marescaux, A., With Contri. by, Mary, B., With Contri. by, Matar, Z., With Contri. by, Meybeck, M., With Contri. by, Mignolet, C., With Contri. by, Moilleron, R., With Contri. by, Mouchel, J.-M., With Contri. by, Moulin, L., With Contri. by, Muresan, B., With Contri. by, Nguyen, P. T., With Contri. by, Oziol, L., With Contri. by, Palos-Ladeiro, M., With Contri. by, Parlanti, E., With Contri. by, Passy, P., With Contri. by, Petit, F., With Contri. by, Puech, T., With Contri. by, Queyrel, W., With Contri. by, Raimonet, M., With Contri. by, Riviére, A., With Contri. by, Rocher, V., With Contri. by, Schott, C., With Contri. by, Schuite, J., With Contri. by, Seguin, L., With Contri. by, Servais, P., With Contri. by, Silvestre, M., With Contri. by, Soares-Pereira, C., With Contri. by, Tales, E., With Contri. by, Tallec, G., With Contri. by, Tassin, B., With Contri. by, Teil, M.-J., With Contri. by, Théry, S., With Contri. by, Thevenot, D., With Contri. by, Thieu, V., With Contri. by, Tournebize, J., With Contri. by, Tramoy, R., With Contri. by, Treilles, R., With Contri. by, Varrault, G., With Contri. by, Viennot, P., With Contri. by, Vilmin, L., With Contri. by, and Wurtzer, S., With Contri. by

Published
2021
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187. Cardiomuscular Biomarkers in the Diagnosis and Prognostication of Immune Checkpoint Inhibitor Myocarditis

Author

Lehmann, Lorenz H., Heckmann, Markus B., Bailly, Guillaume, Finke, Daniel, Procureur, Adrien, Power, John R., Stein, Frederic, Bretagne, Marie, Ederhy, Stephane, Fenioux, Charlotte, Hamwy, Omar, Funck-Brentano, Elisa, Romano, Emanuela, Pieroni, Laurence, Münster, Jan P., Allenbach, Yves, Anquetil, Céline, Leonard-Louis, Sarah, Palaskas, Nicolas L., Hayek, Salim S., Katus, Hugo A., Giannitsis, Evangelos, Frey, Norbert, Kaya, Ziya, Moslehi, Javid, Prifti, Edi, Salem, Joe-Elie, Thuny, Franck, Crusz, Shanthini, Asnani, Aarti, Karlstaedt, Anja, Rocher, Fanny, Paven, Elise, Obeid, Michel, Chan, Wei Ting, Flint, Danette L, Arangalage, Dimitri, Courand, Pierre-Yves, Nicol, Martin, Cariou, Eve, Tamura, Yuichi, Florido, Roberta, Francis, Sanjeev, Leong, Darryl, Piriou, Nicolas, Akhter, Nausheen, Shahneen, Sandhu, Itzhaki Ben Zadok, Osnat, Habib, Manhal, Vachhani, Pankit, Peretto, Giovanni, Zhu, Han, Laufer Perl, Michal, Aras, Mandar, Alexandre, Joachim, Lenneman, Carrie, Levenson, Joshua, Deswal, Anita, Zaha, Vlad G., Gaughan, Elizabeth M, Ewer, Steven, Johnson, Douglas, and Baldassarre, Lauren A

Published
2023
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188. A comprehensive urban programme to reduce energy poverty and its effects on health and wellbeing of citizens in six European countries: study protocol of a controlled trial

Author

Merel Stevens, Hein Raat, Maite Ferrando, Beatriz Vallina, Rebeca Lucas, Lucie Middlemiss, Josep Rédon, Elena Rocher, and Amy van Grieken

Subjects
Energy poverty, Social-ecological model, Health-related quality of life, Health inequity, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Nearly 11% of the European population is affected by energy poverty. Energy poverty is defined by the European Commission (2016) as the inability to afford basic energy services to guarantee a decent standard of living. Energy poverty is considered a complex, multidimensional problem that affects environment, housing, urban development, and health. Living in energy poverty conditions is associated with poorer human health and wellbeing. Hence, the WELLBASED intervention programme aims to design, implement and evaluate a comprehensive urban programme, based on the social-ecological model, to reduce energy poverty and its effects on the citizens’ health and wellbeing in six European urban study sites: Valencia, Spain; Heerlen, The Netherlands; Leeds, United Kingdom; Edirne, Turkey; Obuda, Hungary, and; Jelgava, Latvia. Methods A controlled trial is performed. A total of 875 participants are recruited (125–177 per study site) to receive the WELLBASED intervention programme for 12 months (intervention condition) and 875 participants act as controls (control condition). Data will be collected with a baseline measurement at inclusion (T0), and follow-up measurements after 6 months (T1), 12 months (T2), and 18 months (T3). In both study arms, effects of the WELLBASED intervention programme are measured: health-related quality of life (HR-QoL), mental health, frailty in older adults, self-perceived health, chronic conditions, and care utilization. At the same time points, household expenditure on energy and energy consumption are obtained. In the intervention arm, health-monitoring data (i.e. peak flow, oxygen saturation, blood pressure, and heart rate) are obtained monthly and sleep quality with a three-month interval. Household data with regard to temperature, humidity and air quality are collected near real-time by home sensors. Qualitative interviews are conducted in each study site to evaluate the impacts of the WELLBASED intervention programme and to help explain findings. Discussion The WELLBASED intervention programme will provide new insights into the effectiveness of a comprehensive urban programme to tackle energy poverty and its effects on health and wellbeing across Europe. Hence, this study can contribute to European-wide replicable solutions for policy-makers and city practitioners to alleviate energy poverty. Trial registration ISRCTN registry number is ISRCTN14905838 . Date of registration is 15/02/2022.

Published
2022
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189. Modelling the benefits of urine source separation scenarios on wastewater treatment plants within an urban water basin

Author

Gerald Matar, Mathilde Besson, Jennifer Mas, Sam Azimi, Vincent Rocher, and Mathieu Sperandio

Subjects
influent generator, nitrogen removal, urine source separation, wastewater treatment, Environmental technology. Sanitary engineering, TD1-1066
Abstract

Stringent discharge regulations are encouraging researchers to create innovative and sustainable wastewater treatment solutions. Urine source separation (USS) is among the potent approaches that may reduce nutrient peak loads in the influent wastewater and improve nutrient recovery. A phenomenological model was used to simulate dynamic influent properties and predict the advantages gained from implementing USS in an urban water basin. Several scenarios were investigated assuming different levels of deployment: at the entire city, or specifically in office buildings for men's urine only, or for both men and women employees. The results confirmed that all scenarios of urine source separation offered benefits at the treatment plant in terms of reducing nitrogen influent load. The economic benefits in terms of reducing energy consumption for nitrification and decreasing methanol addition for denitrification were quantified, and results confirmed environmental advantages gained from different USS scenarios. Despite larger advantages gained from a global USS rate in an entire city, implementation of a specific USS in office buildings would remain more feasible from a logistical perspective. A significant benefit in terms of reducing greenhouse gas emissions is demonstrated and this was especially due to the high level of N2O emissions avoided in nitrifying biological aerated filter. HIGHLIGHTS A methodology for modelling different urine separation scenarios in an urban area is shown.; An influent generator was calibrated and gives the variation of effluent quality.; Savings in aeration and methanol are quantified at the treatment plant.; Important reduction of greenhouse gas emissions is shown for different recovery techniques.; The benefits are related to the reduction in N2O emissions and N fertilizer substitution.;

Published
2022
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190. Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis

Author

Lingzi Li, Janina Freitag, Christian Asbrand, Bogdan Munteanu, Bei-Tzu Wang, Ekaterina Zezina, Michel Didier, Gilbert Thill, Corinne Rocher, Matthias Herrmann, and Nadine Biesemann

Subjects
Medicine, Science
Abstract

Abstract Rheumatoid arthritis (RA) is characterized by joint infiltration of immune cells and synovial inflammation which leads to progressive disability. Current treatments improve the disease outcome, but the unmet medical need is still high. New discoveries over the last decade have revealed the major impact of cellular metabolism on immune cell functions. So far, a comprehensive understanding of metabolic changes during disease development, especially in the diseased microenvironment, is still limited. Therefore, we studied the longitudinal metabolic changes during the development of murine arthritis by integrating metabolomics and transcriptomics data. We identified an early change in macrophage pathways which was accompanied by oxidative stress, a drop in NAD+ level and induction of glucose transporters. We discovered inhibition of SIRT1, a NAD-dependent histone deacetylase and confirmed its dysregulation in human macrophages and synovial tissues of RA patients. Mining this database should enable the discovery of novel metabolic targets and therapy opportunities in RA.

Published
2022
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191. Supplementary material to "Global Methane Budget 2000–2020"

Author

Saunois, Marielle, primary, Martinez, Adrien, additional, Poulter, Benjamin, additional, Zhang, Zhen, additional, Raymond, Peter, additional, Regnier, Pierre, additional, Canadell, Joseph G., additional, Jackson, Robert B., additional, Patra, Prabir K., additional, Bousquet, Philippe, additional, Ciais, Philippe, additional, Dlugokencky, Edward J., additional, Lan, Xin, additional, Allen, George H., additional, Bastviken, David, additional, Beerling, David J., additional, Belikov, Dmitry A., additional, Blake, Donald R., additional, Castaldi, Simona, additional, Crippa, Monica, additional, Deemer, Bridget R., additional, Dennison, Fraser, additional, Etiope, Giuseppe, additional, Gedney, Nicola, additional, Höglund-Isaksson, Lena, additional, Holgerson, Meredith A., additional, Hopcroft, Peter O., additional, Hugelius, Gustaf, additional, Ito, Akihito, additional, Jain, Atul K., additional, Janardanan, Rajesh, additional, Johnson, Matthew S., additional, Kleinen, Thomas, additional, Krummel, Paul, additional, Lauerwald, Ronny, additional, Li, Tingting, additional, Liu, Xiangyu, additional, McDonald, Kyle C., additional, Melton, Joe R., additional, Mühle, Jens, additional, Müller, Jurek, additional, Murguia-Flores, Fabiola, additional, Niwa, Yosuke, additional, Noce, Sergio, additional, Pan, Shufen, additional, Parker, Robert J., additional, Peng, Changhui, additional, Ramonet, Michel, additional, Riley, William J., additional, Rocher-Ros, Gerard, additional, Rosentreter, Judith A., additional, Sasakawa, Motoki, additional, Segers, Arjo, additional, Smith, Steven J., additional, Stanley, Emily H., additional, Thanwerdas, Joel, additional, Tian, Hanquin, additional, Tsuruta, Aki, additional, Tubiello, Francesco N., additional, Weber, Thomas S., additional, van der Werf, Guido, additional, Worthy, Doug E., additional, Xi, Yi, additional, Yoshida, Yukio, additional, Zhang, Wenxin, additional, Zheng, Bo, additional, Zhu, Qing, additional, Zhu, Qiuan, additional, and Zhuang, Qianlai, additional

Published
2024
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192. Global Methane Budget 2000–2020

Author

Saunois, Marielle, primary, Martinez, Adrien, additional, Poulter, Benjamin, additional, Zhang, Zhen, additional, Raymond, Peter, additional, Regnier, Pierre, additional, Canadell, Joseph G., additional, Jackson, Robert B., additional, Patra, Prabir K., additional, Bousquet, Philippe, additional, Ciais, Philippe, additional, Dlugokencky, Edward J., additional, Lan, Xin, additional, Allen, George H., additional, Bastviken, David, additional, Beerling, David J., additional, Belikov, Dmitry A., additional, Blake, Donald R., additional, Castaldi, Simona, additional, Crippa, Monica, additional, Deemer, Bridget R., additional, Dennison, Fraser, additional, Etiope, Giuseppe, additional, Gedney, Nicola, additional, Höglund-Isaksson, Lena, additional, Holgerson, Meredith A., additional, Hopcroft, Peter O., additional, Hugelius, Gustaf, additional, Ito, Akihito, additional, Jain, Atul K., additional, Janardanan, Rajesh, additional, Johnson, Matthew S., additional, Kleinen, Thomas, additional, Krummel, Paul, additional, Lauerwald, Ronny, additional, Li, Tingting, additional, Liu, Xiangyu, additional, McDonald, Kyle C., additional, Melton, Joe R., additional, Mühle, Jens, additional, Müller, Jurek, additional, Murguia-Flores, Fabiola, additional, Niwa, Yosuke, additional, Noce, Sergio, additional, Pan, Shufen, additional, Parker, Robert J., additional, Peng, Changhui, additional, Ramonet, Michel, additional, Riley, William J., additional, Rocher-Ros, Gerard, additional, Rosentreter, Judith A., additional, Sasakawa, Motoki, additional, Segers, Arjo, additional, Smith, Steven J., additional, Stanley, Emily H., additional, Thanwerdas, Joel, additional, Tian, Hanquin, additional, Tsuruta, Aki, additional, Tubiello, Francesco N., additional, Weber, Thomas S., additional, van der Werf, Guido, additional, Worthy, Doug E., additional, Xi, Yi, additional, Yoshida, Yukio, additional, Zhang, Wenxin, additional, Zheng, Bo, additional, Zhu, Qing, additional, Zhu, Qiuan, additional, and Zhuang, Qianlai, additional

Published
2024
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