Search

Your search keyword '"Randazzo, Antonio"' showing total 792 results
Start Over Author "Randazzo, Antonio"
792 results on '"Randazzo, Antonio"'

153. Cyclic phosphate-linked oligosaccharides (CYPLOS): synthesis and conformational behaviour of novel oligosaccharide analogues

Author

DI FABIO, GIOVANNI, RANDAZZO, ANTONIO, J. DONOFRIO, C. AUSIN, A. GRANDAS, E. PEDROSO, DE NAPOLI, LORENZO, MONTESARCHIO, DANIELA, DI FABIO, Giovanni, Randazzo, Antonio, J., Donofrio, C., Ausin, A., Granda, E., Pedroso, DE NAPOLI, Lorenzo, and Montesarchio, Daniela

Subjects
cyclic oligosaccharide, phosphotriester methodology, phosphodiester bond, NMR analysis, phosphoramidite chemistry
Abstract

CyPLOS (cyclic phosphate-linked oligosaccharides), that is, novel cyclic oligosaccharide surrogates, consisting of two, three, and four phenyl-â-D-glucopyranoside units, 4,6-linked through stable phosphodiester bonds, were prepared by a straightforward and efficient solid-phase protocol. The assembly of the linear precursors was achieved by standard phosphoramidite chemistry on an automated DNA synthesizer, using a suitably protected 4-phosphoramidite derivative of D-glucose as the building block. For the crucial cyclization step a phosphotriester methodology was exploited, followed by a mild basic treatment releasing the desired cyclic molecules in solution in a highly pure form. The cyclic dimer and trimer were also independently prepared by classical solution synthesis, basically following the same approach. The solution structural preferences of the cyclic dimer and trimer, obtained by detailed NMR analysis, are also reported.

Published
2006

155. Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

Author

Amato, Jussara, primary, Morigi, Rita, additional, Pagano, Bruno, additional, Pagano, Alessia, additional, Ohnmacht, Stephan, additional, De Magis, Alessio, additional, Tiang, Yee-Peng, additional, Capranico, Giovanni, additional, Locatelli, Alessandra, additional, Graziadio, Alessandra, additional, Leoni, Alberto, additional, Rambaldi, Mirella, additional, Novellino, Ettore, additional, Neidle, Stephen, additional, and Randazzo, Antonio, additional

Published
2016
Full Text
View/download PDF

156. Everolimus induces Met inactivation by disrupting the FKBP12/Met complex

Author

Raimondo, Lucia, primary, D’Amato, Valentina, additional, Servetto, Alberto, additional, Rosa, Roberta, additional, Marciano, Roberta, additional, Formisano, Luigi, additional, Di Mauro, Concetta, additional, Orsini, Roberta Clara, additional, Cascetta, Priscilla, additional, Ciciola, Paola, additional, De Maio, Ana Paula, additional, Di Renzo, Maria Flavia, additional, Cosconati, Sandro, additional, Bruno, Agostino, additional, Randazzo, Antonio, additional, Napolitano, Filomena, additional, Montuori, Nunzia, additional, Veneziani, Bianca Maria, additional, De Placido, Sabino, additional, and Bianco, Roberto, additional

Published
2016
Full Text
View/download PDF

159. Binding of distamycin and analogues to quadruplex structures

Author

PAGANO, BRUNO, RANDAZZO, ANTONIO, MAYOL, LUCIANO, GIANCOLA, CONCETTA, V. Esposito, C. A. Mattia, G. Barone, Pagano, Bruno, V., Esposito, Randazzo, Antonio, C. A., Mattia, G., Barone, Mayol, Luciano, and Giancola, Concetta

Published
2005

161. Stabilità di una quadrupla elica di LNA

Author

PETRACCONE, LUIGI, ERRA, EVA, ESPOSITO, VERONICA, RANDAZZO, ANTONIO, MAYOL, LUCIANO, BARONE, GUIDO, GIANCOLA, CONCETTA, Petraccone, Luigi, Erra, Eva, Esposito, Veronica, Randazzo, Antonio, Mayol, Luciano, Barone, Guido, and Giancola, Concetta

Subjects
quadruple eliche di DNA, stabilità termodinamica, oligonucleotidi modificati
Abstract

The design of modified nucleic acid aptamers is improved by considering thermodynamics and kinetics of their association/dissociation processes. Locked Nucleic Acids (LNA) is a promising class of nucleic acid analogs. In this work the thermodynamic and kinetic properties of a LNA quadruplex formed by the TGGGT sequence, containing only conformationally restricted LNA residues, are reported and compared to those of 2'-OMe-RNA (O-RNA) and DNA quadruplexes. The thermodynamic analysis indicates that the sugar-modified quadruplexes (LNA and O-RNA) are stabilized by entropic effects. The kinetic analysis shows that LNA and O-RNA quadruplexes are characterized by a slower dissociation and a faster association with respect to DNA quadruplex. Interestingly, the LNA quadruplex formation process shows a second-order kinetics with respect to single strand concentration and has a negative activation energy. To explain these data, a mechanism for tetramer formation with two intermediate states was proposed.

Published
2005

162. A Unique Capsular Polysaccharide Structure from the Psychrophilic Marine Bacterium Colwellia psychrerythraea 34H That Mimics Antifreeze (Glyco)proteins

Author

Carillo, Sara, Casillo, Angela, Pieretti, Giuseppina, Parrilli, Ermenegilda, Sannino, Filomena, Bayer-Giraldi, Maddalena, Cosconati, Sandro, Novellino, Ettore, Ewert, Marcela, Deming, Jody W., Lanzetta, Rosa, Marino, Gennaro, Parrilli, Michelangelo, Randazzo, Antonio, Tutino, Maria Luisa, Corsaro, Maria Michela, Carillo, Sara, Casillo, Angela, Pieretti, Giuseppina, Parrilli, Ermenegilda, Sannino, Filomena, Bayer-Giraldi, Maddalena, Cosconati, Sandro, Novellino, Ettore, Ewert, Marcela, Deming, Jody W., Lanzetta, Rosa, Marino, Gennaro, Parrilli, Michelangelo, Randazzo, Antonio, Tutino, Maria Luisa, and Corsaro, Maria Michela

Abstract

The low temperatures of polar regions and high-altitude environments, especially icy habitats, present challenges for many microorganisms. Their ability to live under subfreezing conditions implies the production of compounds conferring cryotolerance. Colwellia psychrerythraea 34H, a γ-proteobacterium isolated from subzero Arctic marine sediments, provides a model for the study of life in cold environments. We report here the identification and detailed molecular primary and secondary structures of capsular polysaccharide from C. psychrerythraea 34H cells. The polymer was isolated in the water layer when cells were extracted by phenol/water and characterized by one- and two-dimensional NMR spectroscopy together with chemical analysis. Molecular mechanics and dynamics calculations were also performed. The polysaccharide consists of a tetrasaccharidic repeating unit containing two amino sugars and two uronic acids bearing threonine as substituent. The structural features of this unique polysaccharide resemble those present in antifreeze proteins and glycoproteins. These results suggest a possible correlation between the capsule structure and the ability of C. psychrerythraea to colonize subfreezing marine environments.

Published
2015

164. Physico-chemical studies of quadruple helices of modified human telomeric DNA

Author

ERRA, EVA, PETRACCONE, LUIGI, RANDAZZO, ANTONIO, GALEONE, ALDO, ESPOSITO, VERONICA, BARONE, GUIDO, GIANCOLA, CONCETTA, Erra, Eva, Petraccone, Luigi, Randazzo, Antonio, Galeone, Aldo, Esposito, Veronica, Barone, Guido, and Giancola, Concetta

Subjects
quadruple eliche di DNA, chimica-fisica, biofisica
Abstract

The ends of chromosomes, termed telomeres, is composed of telomeric DNA and various telomere-associated proteins. Although most of telomeric DNA is double-stranded, the extreme 3'-end of the telomere consists of single-stranded G-rich DNA overhangs [1]. Human telomeric DNA contains tandem repeats of the sequence TTAGGG and the guanine-rich strand folds into an intramolecular quadruplex structure in Na+ solution. The structure of the telomeric DNA has been extensively studied in recent years due to the identification of a possible biological role and potential biotechnological and therapeutic applications. These structures seem to be involved in the recombination at G-rich sequences, telomere protection and elongation and transcriptional regulation [2]. The ability to chemically synthesize oligonucleotide analogues has opened up the opportunity to observe changes in their structures and activities that occur even upon single residue substitution [3]. The incorporation of modified bases into oligonucleotides may indeed produce useful changes in physical and biological properties of the resulting DNA fragments. In this work, the physico-chemical properties of quadruplex structures of the human telomeric repeat oligonucleotide d(TAGGGT), d(AGGGT) and modified sequences were compared. The adenine was substituted by 2'-deoxy-8-(propyn-1-yl)adenosine (AAPr) and by 8-bromodeoxyadenosine (A ABr).

Published
2004

165. RELATIVE STABILITY OF QUADRUPLEXES CONTAING DIFFERENT NUMBER OF G-TETRADS

Author

BARONE, GUIDO, GIANCOLA, CONCETTA, PETRACCONE, LUIGI, RANDAZZO, ANTONIO, MAYOL, LUCIANO, I. DURO, ERRA E, ESPOSITO, VERONICA, MATTIA C. A., Barone, Guido, Giancola, Concetta, I., Duro, Petraccone, Luigi, Erra, E, Esposito, Veronica, Randazzo, Antonio, Mayol, Luciano, and Mattia, C. A.

Published
2004

166. Configuration assignment in small organic molecules via residual dipolar couplings

Author

MANGONI, ALFONSO, ESPOSITO, VERONICA, RANDAZZO, ANTONIO, Mangoni, Alfonso, Esposito, Veronica, and Randazzo, Antonio

Abstract

Here we propose a new method to assign relative configurations of stereocenters in small organic molecules by using residual dipolar couplings; the main advantage of this method is that spatial proximity of the stereocenters is not required.

Published
2003

169. Molecular basis of phospholipase A2 inhibition by petrosaspongiolide M

Author

DAL PIAZ, F, Casapullo, A, Riccio, R, Marino, G, GOMEZ PALOMA, L., RANDAZZO, ANTONIO, PUCCI, PIETRO, DAL PIAZ, F, Casapullo, A, Randazzo, Antonio, Riccio, R, Pucci, Pietro, Marino, G, and GOMEZ PALOMA, L.

Subjects
inhibitor, enzyme, natural products, anti-inflammatory compound, mass spectrometry
Abstract

Petrosaspongiolide M (PM) is an anti-inflammatory marine metabolite that displays a potent inhibitory activity toward group II and III secretory phospholipase A2 (PLA2) enzymes. The details of the mechanism, which leads to a covalent adduct between PLA2 and γ-hydroxybutenolide-containing molecules such as PM, are still a matter of debate. In this paper the covalent binding of PM to bee venom PLA2 has been investigated by mass spectrometry and molecular modeling. The mass increment observed for the PM-PLA2 adduct is consistent with the formation of a Schiff base by reaction of a PLA2 amino group with the hemiacetal function (masked aldehyde) at the C-25 atom of the PM γ-hydroxybutenolide ring. Proteolysis of the modified PLA2 by the endoprotease LysC followed by HPLC MS analysis allowed us to establish that the PLA2 α-amino terminal group of the lle-1 residue was the only covalent binding site for PM. The stoichiometry of the reaction between PM and PLA2 was also monitored and results showed that even with excess inhibitor, the prevalent product is a 1:1 (inhibitor:enzyme) adduct, although a 2:1 adduct is present as a minor component. The 2:1 adduct was also characterized, which showed that the second site of reaction is located at the ε-amino group of the Lys-85 residue. Similar results in terms of the reaction profile, mass increments, and location of the PLA2 binding site were obtained for manoalide, a paradigm for irreversible PLA2 inhibitors, which suggests that the present results may be considered of more general interest within the field of anti-inflammatory sesterterpenes that contain the γ-hydroxybutenolide pharmacophore. Finally, a 3D model, constrained by the above experimental results, was obtained by docking the inhibitor molecule into the PLA2 binding site through AFFINITY calculations. The model provides an interesting insight into the PM-PLA2 inhibition process and may prove useful in the design of new anti-inflammatory agents that target PLA2 secretory enzymes.

Published
2002

170. Bioactive macrolides and cyclopeptides from South Pacific sponges

Author

C. Bassarello, A. Napolitano, G. Bifulco, I. Bruno, A. Casapullo, R. Riccio, L. Gomez Paloma, RANDAZZO, ANTONIO, ZAMPELLA, ANGELA, C., Bassarello, A., Napolitano, G., Bifulco, I., Bruno, A., Casapullo, Randazzo, Antonio, Zampella, Angela, R., Riccio, and L., Gomez Paloma

Published
2000

171. Sphinxolides E-G and Redispongiolide C: Four New Cytotoxic Macrolides from the New Caledonian Lithistida Sponges Neosiphonia superstes and Redispongia coerulea

Author

S. CARBONELLI, L. GOMEZ PALOMA, ZAMPELLA, ANGELA, RANDAZZO, ANTONIO, S., Carbonelli, Zampella, Angela, Randazzo, Antonio, and L., GOMEZ PALOMA

Abstract

Four new macrolides (7-10), structurally related to known sphinxolides (1-4) and reidispongiolides (5-6), have been isolated following a reinvestigation of Neosiphonia superstes and Reidispongia coerulea, two Lithistida sponges collected in the deep waters off New Caledonia. In this paper we report their structure elucidation based on spectral data (mainly 2D-NMR and MS) as well as their cytotoxicity determined on a panel of 60 human cancer cell lines.

Published
1999

172. Effects of Petrosaspongiolide M, a Novel Human Synovial Phospholipase A2 Inhibitor, on Acute and Chronic Inflammation

Author

P. GARCIA PASTOR, LUIGI GOMEZ PALOMA, MARIA J. ALCARAZ, M. PAYA, RANDAZZO, ANTONIO, P., GARCIA PASTOR, Randazzo, Antonio, LUIGI GOMEZ, Paloma, MARIA J., Alcaraz, and M., Paya

Abstract

The marine product petrosaspongiolide M is a novel inhibitor of phospholipase A(2) (PLA(2)), showing selectivity for secretory PLA, Versus cytosolic PLA(2), with a potency on the human synovial enzyme (group II) similar to that of manoalide. This compound was more potent than manoalide on bee venom PLA, (group III) and had no effect on group I enzymes (Naja naja and porcine pancreatic PLA(2)). Inhibition of PLA(2) was also observed in vivo in the zymosan-injected rat air pouch, on the secretory enzyme accumulated in the pouch exudate. Petrosaspongiolide M decreased carrageenan paw edema in mice after the oral administration of 5, 10, or 20 mg/kg. This marine metabolite (0.01-1.0 mu mol/pouch) induced a dose-dependent reduction in the levels of prostaglandin (PG)E-2, leukotriene B-4, and tumor necrosis factor-alpha in the mouse air pouch injected with zymosan 4 h after the stimulus. It also had a weaker effect on cell migration. The inflammatory response of adjuvant arthritis was reduced by petrosaspongiolide M, which also inhibited leukotriene B-4 levels in serum and PGE(2) levels in paw homogenates. In contrast with indomethacin, this marine compound did not reduce PGE(2) levels in stomach homogenates. Petrosaspongiolide M is a new inhibitor of secretory PLA(2) in vitro and in vivo, with anti-inflammatory properties in acute and chronic inflammation.

Published
1999

173. Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

Author

Zizza, Pasquale, primary, Cingolani, Chiara, additional, Artuso, Simona, additional, Salvati, Erica, additional, Rizzo, Angela, additional, D'Angelo, Carmen, additional, Porru, Manuela, additional, Pagano, Bruno, additional, Amato, Jussara, additional, Randazzo, Antonio, additional, Novellino, Ettore, additional, Stoppacciaro, Antonella, additional, Gilson, Eric, additional, Stassi, Giorgio, additional, Leonetti, Carlo, additional, and Biroccio, Annamaria, additional

Published
2015
Full Text
View/download PDF

174. Src inhibitors act through different mechanisms in Non-Small Cell Lung Cancer models depending on EGFR and RAS mutational status

Author

Formisano, Luigi, primary, D'Amato, Valentina, additional, Servetto, Alberto, additional, Brillante, Simona, additional, Raimondo, Lucia, additional, Di Mauro, Concetta, additional, Marciano, Roberta, additional, Orsini, Roberta Clara, additional, Cosconati, Sandro, additional, Randazzo, Antonio, additional, Parsons, Sarah J., additional, Montuori, Nunzia, additional, Veneziani, Bianca Maria, additional, De Placido, Sabino, additional, Rosa, Roberta, additional, and Bianco, Roberto, additional

Published
2015
Full Text
View/download PDF

178. A Unique Capsular Polysaccharide Structure from the Psychrophilic Marine Bacterium Colwellia psychrerythraea 34H That Mimics Antifreeze (Glyco)proteins

Author

Carillo, Sara, primary, Casillo, Angela, additional, Pieretti, Giuseppina, additional, Parrilli, Ermenegilda, additional, Sannino, Filomena, additional, Bayer-Giraldi, Maddalena, additional, Cosconati, Sandro, additional, Novellino, Ettore, additional, Ewert, Marcela, additional, Deming, Jody W., additional, Lanzetta, Rosa, additional, Marino, Gennaro, additional, Parrilli, Michelangelo, additional, Randazzo, Antonio, additional, Tutino, Maria L., additional, and Corsaro, M. Michela, additional

Published
2015
Full Text
View/download PDF

179. Identification of novel interactors of human telomeric G-quadruplex DNA

Author

Pagano, Bruno, primary, Margarucci, Luigi, additional, Zizza, Pasquale, additional, Amato, Jussara, additional, Iaccarino, Nunzia, additional, Cassiano, Chiara, additional, Salvati, Erica, additional, Novellino, Ettore, additional, Biroccio, Annamaria, additional, Casapullo, Agostino, additional, and Randazzo, Antonio, additional

Published
2015
Full Text
View/download PDF

180. Axinellins A and B: New Proline-Containg Antiproliferative Cyclopeptides from the Vanuatu Sponge Axinella carteri

Author

RANDAZZO, ANTONIO, FABRIZIO DAL PIAZ, STEFANIA ORRÙ, P. CÉCILE DEBITUS, CHRISTOS ROUSSAKIS, PIERO PUCCI, LUIGI GOMEZ PALOMA, Randazzo, Antonio, FABRIZIO DAL PIAZ, Stefania, Orrù, CÉCILE DEBITUS, P., Christos, Roussaki, Pucci, Pietro, and LUIGI GOMEZ PALOMA

Abstract

Two new bioactive cyclopeptides, named axinellins A (1) and B (2) have been isolated from the marine sponge Axinella carteri. Their structure elucidation was based on two-dimensional (2D) NMR (500 MHz) as well as HRFABMS and ESMS/MS data. All amino acid residues derived from a;axinellins A and B were found to possess L configuration at Co by HPLC analysis of their FDAA derivatives (Marfey's method). The amino acid sequence of 1 and 2 was established on the basis of tandem mass spectrometry data (ESMS/MS) and on H-1-H-1 through-space connectivities observed in NOESY and ROESY spectra. Axinellins A (1) and B (2) exhibited moderate in vitro antitumor activity against human broncopulmonary non-small-cell-lung-carcinoma lines (NSCLC-NG) with IC50 values of 3.0 and 7.3 mu g/ml, respectively.

Published
1998

181. Metaboliti secondari ad attività citotossica, antivirale ed antiinfiammatoria da invertebrati marini del Sud Pacifico

Author

D'AURIA, MARIA VALERIA, DE MARINO, SIMONA, RANDAZZO, ANTONIO, ZAMPELLA, ANGELA, ZOLLO, FRANCO, G. Bifulco, I. Bruno, A. Casapullo, C. Giannini, L. Gomez Paloma, M. Iorizzi, R. Riccio, Comitato scientifico e organizzatore del congresso, D'Auria, MARIA VALERIA, G., Bifulco, I., Bruno, A., Casapullo, DE MARINO, Simona, C., Giannini, L., Gomez Paloma, M., Iorizzi, Randazzo, Antonio, R., Riccio, Zampella, Angela, and Zollo, Franco

Published
1998

189. Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

Author

Salvati, Erica, primary, Zizza, Pasquale, additional, Rizzo, Angela, additional, Iachettini, Sara, additional, Cingolani, Chiara, additional, D’Angelo, Carmen, additional, Porru, Manuela, additional, Randazzo, Antonio, additional, Pagano, Bruno, additional, Novellino, Ettore, additional, Pisanu, Maria Elena, additional, Stoppacciaro, Antonella, additional, Spinella, Francesca, additional, Bagnato, Anna, additional, Gilson, Eric, additional, Leonetti, Carlo, additional, and Biroccio, Annamaria, additional

Published
2013
Full Text
View/download PDF

190. Exploring the Chemical Space of G-Quadruplex Binders: Discovery of a Novel Chemotype Targeting the Human Telomeric Sequence

Author

Di Leva, Francesco Saverio, primary, Zizza, Pasquale, additional, Cingolani, Chiara, additional, D’Angelo, Carmen, additional, Pagano, Bruno, additional, Amato, Jussara, additional, Salvati, Erica, additional, Sissi, Claudia, additional, Pinato, Odra, additional, Marinelli, Luciana, additional, Cavalli, Andrea, additional, Cosconati, Sandro, additional, Novellino, Ettore, additional, Randazzo, Antonio, additional, and Biroccio, Annamaria, additional

Published
2013
Full Text
View/download PDF

192. NMR spectrometers as 'magnetic tongues': prediction of sensory descriptors in canned tomatoes

Author

Malmendal, Anders, Amoresano, Claudia, Trotta, Roberta, Lauri, Ilaria, De Tito, Stefano, Novellino, Ettore, Randazzo, Antonio, Malmendal, Anders, Amoresano, Claudia, Trotta, Roberta, Lauri, Ilaria, De Tito, Stefano, Novellino, Ettore, and Randazzo, Antonio

Abstract

The perception of odor and flavor of food is a complicated physiological and psychological process that cannot be explained by simple models. Quantitative descriptive analysis is a technique used to describe sensory features. Nevertheless, the availability of a number of instrumental techniques has opened up the possibility to calibrate the sensory perception. In this frame, we have tested the potentiality of nuclear magnetic resonance spectroscopy as a predictive tool to measure sensory descriptors. In particular, we have used an NMR metabolomic approach that allowed us to differentiate the analyzed samples based on their chemical composition. We were able to correlate the NMR metabolomic fingerprints recorded for canned tomato samples to the sensory descriptors bitterness, sweetness, sourness, saltiness, tomato and metal taste, redness, and density, suggesting that NMR might be a very useful tool for the characterization of sensory features of tomatoes.

Published
2011

193. Fluorescence Enhancement upon G-Quadruplex Folding: Synthesis, Structure, and Biophysical Characterization of a Dansyl/Cyclodextrin-Tagged Thrombin Binding Aptamer

Author

De Tito, Stefano, primary, Morvan, François, additional, Meyer, Albert, additional, Vasseur, Jean-Jacques, additional, Cummaro, Annunziata, additional, Petraccone, Luigi, additional, Pagano, Bruno, additional, Novellino, Ettore, additional, Randazzo, Antonio, additional, Giancola, Concetta, additional, and Montesarchio, Daniela, additional

Published
2013
Full Text
View/download PDF

194. The G‐Triplex DNA

Author

Limongelli, Vittorio, primary, De Tito, Stefano, additional, Cerofolini, Linda, additional, Fragai, Marco, additional, Pagano, Bruno, additional, Trotta, Roberta, additional, Cosconati, Sandro, additional, Marinelli, Luciana, additional, Novellino, Ettore, additional, Bertini, Ivano, additional, Randazzo, Antonio, additional, Luchinat, Claudio, additional, and Parrinello, Michele, additional

Published
2013
Full Text
View/download PDF

196. Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

Author

Cosconati, Sandro, primary, Rizzo, Angela, additional, Trotta, Roberta, additional, Pagano, Bruno, additional, Iachettini, Sara, additional, De Tito, Stefano, additional, Lauri, Ilaria, additional, Fotticchia, Iolanda, additional, Giustiniano, Mariateresa, additional, Marinelli, Luciana, additional, Giancola, Concetta, additional, Novellino, Ettore, additional, Biroccio, Annamaria, additional, and Randazzo, Antonio, additional

Published
2012
Full Text
View/download PDF

197. State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders

Author

Pagano, Bruno, primary, Cosconati, Sandro, additional, Gabelica, Valerie, additional, Petraccone, Luigi, additional, De Tito, Stefano, additional, Marinelli, Luciana, additional, La Pietra, Valeria, additional, Saverio di Leva, Francesco, additional, Lauri, Ilaria, additional, Trotta, Roberta, additional, Novellino, Ettore, additional, Giancola, Concetta, additional, and Randazzo, Antonio, additional

Published
2012
Full Text
View/download PDF

200. The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: Biophysical and molecular modeling studies

Author

Petraccone, Luigi, primary, Fotticchia, Iolanda, additional, Cummaro, Annunziata, additional, Pagano, Bruno, additional, Ginnari-Satriani, Luca, additional, Haider, Shozeb, additional, Randazzo, Antonio, additional, Novellino, Ettore, additional, Neidle, Stephen, additional, and Giancola, Concetta, additional

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results