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3,282 results on '"Prasad, Ram"'

159. Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension

Author

Kumar, Sushil, primary, Mickael, Claudia, additional, Kumar, Rahul, additional, Prasad, Ram Raj, additional, Campbell, Nzali V., additional, Zhang, Hui, additional, Li, Min, additional, McKeon, B. Alexandre, additional, Allen, Thaddeus E., additional, Graham, Brian B., additional, Yu, Yen-Rei A., additional, and Stenmark, Kurt R., additional

Published
2024
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163. Developing a framework for understanding policy decision-making behaviors in the transition of a HIV prevention program towards sustainability: a case study from Zambia’s voluntary medical male circumcision program

Author

Gantayat, Nishan, primary, Baer, James, additional, Gangaramany, Alok, additional, Kretschmer, Steve, additional, Surana, Rasi, additional, Samona, Alick, additional, Mukambe, Njekwa, additional, Jere, Bright, additional, Chinsenga, Tina, additional, Prasad, Ram, additional, Goetschius, Stephen, additional, and Sharma, Saransh, additional

Published
2024
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178. List of contributors

Author

Adassooriya, Nadeesh M., primary, Azcune, Germán, additional, Banerjee, Priyabrata, additional, Barrantes, Kenia, additional, Bej, Sourav, additional, Bhattacharyya, Liza Handique, additional, Bhattacharyya, Pranaba N., additional, Borah, Siddhartha Narayan, additional, Campana, Eloiza H., additional, Chacón, Luz, additional, Chande, Othman, additional, Cid, Ángeles, additional, Coelho, Susana, additional, Colazzo, Marcos, additional, Dhir, Bhupinder, additional, Esperanza, Marta, additional, Eunice, Mureithi, additional, García-Córcoles, María Teresa, additional, Ghahari, Saeid, additional, Ghahari, Sajjad, additional, Ghahari, Somayeh, additional, Gómez-Regalado, María del Carmen, additional, Grobelak, Anna, additional, Gündoğdu, Sedat, additional, Harimawan, Ardiyan, additional, Hazra, Abhijit, additional, Herrero, Concepción, additional, Hossein, Miraji, additional, Indarto, Antonius, additional, Islam, Nazim Forid, additional, Karwal, Preeti, additional, Khan, Farhan R., additional, Koch, Niharika, additional, Kowalska, Aneta, additional, Madanayake, Nadun H., additional, Mançano, Stella M.C.N., additional, Markley, Laura A., additional, Martín-Bueno, Julia, additional, Martín-Pozo, Laura, additional, Mihai, Florin-Constantin, additional, Mittal, Pooja, additional, Mondal, Amita, additional, Mondal, Udayan, additional, Moscoso-Ruiz, Inmaculada, additional, Moura, Leonardo, additional, Muela, Agustina, additional, Nag, Somrita, additional, Nagar, Garima, additional, Nematzadeh, Ghorban Ali, additional, Ngassapa, Faustin, additional, Olivelli, Arianna, additional, Pareja, Lucía, additional, Pastorinho, M. Ramiro, additional, Pathak, Pankaj, additional, Paul, Suparna, additional, Perera, Niranjalie, additional, Pérez-Parada, Andrés, additional, Picão, Renata C., additional, Prasad, Ram, additional, Reyes, Liliana, additional, Rioboo, Carmen, additional, Rivera-Montero, Luis, additional, Saikia, Rashmi Rekha, additional, Sarma, Hemen, additional, Sen, Suparna, additional, Seoane, Marta, additional, Setiadi, Tjandra, additional, Sharma, Poonam, additional, Singh, Archana, additional, Singh, Indrakant K., additional, Sonowal, Songita, additional, Sousa, Ana Catarina A., additional, Sumampouw, Giovanni A., additional, Sungur, Şana, additional, Sushil, Kumar, additional, Tripathi, Charu, additional, Valente, João Vasco, additional, van Emmerik, Tim, additional, and Zafra-Gómez, Alberto, additional

Published
2022
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194. Modulated Self-Assembly of Catalytically Active Metal-Organic Nanosheets Containing Zr6 Clusters and Dicarboxylate Ligands

Author

Prasad, Ram R. R., Boyadjieva, Sophia S., Zhou, Guojun, Tan, Jiangtian, Firth, Francesca C. N., Ling, Sanliang, Huang, Zhehao, Cliffe, Matthew J., Foster, Jonathan A., Forgan, Ross S., Prasad, Ram R. R., Boyadjieva, Sophia S., Zhou, Guojun, Tan, Jiangtian, Firth, Francesca C. N., Ling, Sanliang, Huang, Zhehao, Cliffe, Matthew J., Foster, Jonathan A., and Forgan, Ross S.

Abstract

Two-dimensional metal–organic nanosheets (MONs) have emerged as attractive alternatives to their three-dimensional metal–organic framework (MOF) counterparts for heterogeneous catalysis due to their greater external surface areas and higher accessibility of catalytically active sites. Zr MONs are particularly prized because of their chemical stability and high Lewis and Brønsted acidities of the Zr clusters. Herein, we show that careful control over modulated self-assembly and exfoliation conditions allows the isolation of the first example of a two-dimensional nanosheet wherein Zr6 clusters are linked by dicarboxylate ligands. The hxl topology MOF, termed GUF-14 (GUF = Glasgow University Framework), can be exfoliated into monolayer thickness hns topology MONs, and acid-induced removal of capping modulator units yields MONs with enhanced catalytic activity toward the formation of imines and the hydrolysis of an organophosphate nerve agent mimic. The discovery of GUF-14 serves as a valuable example of the undiscovered MOF/MON structural diversity extant in established metal–ligand systems that can be accessed by harnessing the power of modulated self-assembly protocols.

Published
2024
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198. An Immunoinformatic‐Based In Silico Identification on the Creation of a Multiepitope‐Based Vaccination Against the Nipah Virus.

Author

Kaur, Beant, Karnwal, Arun, Bansal, Anu, Malik, Tabarak, and Prasad, Ram

Subjects
IMMUNIZATION, PARAMYXOVIRUSES
Abstract

The zoonotic viruses pose significant threats to public health. Nipah virus (NiV) is an emerging virus transmitted from bats to humans. The NiV causes severe encephalitis and acute respiratory distress syndrome, leading to high mortality rates, with fatality rates ranging from 40% to 75%. The first emergence of the disease was found in Malaysia in 1998–1999 and later in Bangladesh, Cambodia, Timor‐Leste, Indonesia, Singapore, Papua New Guinea, Vietnam, Thailand, India, and other South and Southeast Asian nations. Currently, no specific vaccines or antiviral drugs are available. The potential advantages of epitope‐based vaccines include their ability to elicit specific immune responses while minimizing potential side effects. The epitopes have been identified from the conserved region of viral proteins obtained from the UniProt database. The selection of conserved epitopes involves analyzing the genetic sequences of various viral strains. The present study identified two B cell epitopes, seven cytotoxic T lymphocyte (CTL) epitopes, and seven helper T lymphocyte (HTL) epitope interactions from the NiV proteomic inventory. The antigenic and physiological properties of retrieved protein were analyzed using online servers ToxinPred, VaxiJen v2.0, and AllerTOP. The final vaccine candidate has a total combined coverage range of 80.53%. The tertiary structure of the constructed vaccine was optimized, and its stability was confirmed with the help of molecular simulation. Molecular docking was performed to check the binding affinity and binding energy of the constructed vaccine with TLR‐3 and TLR‐5. Codon optimization was performed in the constructed vaccine within the Escherichia coli K12 strain, to eliminate the danger of codon bias. However, these findings must require further validation to assess their effectiveness and safety. The development of vaccines and therapeutic approaches for virus infection is an ongoing area of research, and it may take time before effective interventions are available for clinical use. [ABSTRACT FROM AUTHOR]

Published
2024
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