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2,906 results on '"Polak, M"'

152. Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study

Author

Bowman P., Sulen A., Barbetti F., Beltrand J., Svalastoga P., Codner E., Tessmann E. H., Juliusson P. B., Skrivarhaug T., Pearson E. R., Flanagan S. E., Babiker T., Thomas N. J., Shepherd M. H., Ellard S., Klimes I., Szopa M., Polak M., Iafusco D., Hattersley A. T., Njolstad P. R., Aisenberg J., Akkurt I., Abdul-Latif H., Al-Abdullah A., Barak L., Van Den Bergh J., Bertrand A. -M., Bizzarri C., Bonfanti R., Bruel H., Burrows A., Cadario F., Cameron F. J., Carson D., Cartigny M., Cauvin V., Cave H., Chakera A., Chetan R., Chiari G., Couch B., Coutant R., Cummings E., Dankovcikova A., Davis L., Deiss D., Delvecchio M., Faleschini E., Fauret A. -L., Finn R., Ford T., Franco E. D., Gallen B. D., Gasperikova D., Guntamukkala P., Hakeem V., Hasegawa S., Hathout E. H., Heffernan E., Hill D., Ho J., Hoarau M., Holl R., Hoddinott R., Houghton J., Howard N., Hughes N., Hunter I., Hogasen A. K., Kuulasmaa H., Ioacara S., Iotova V., Irgens H., Jaap A., Jones K., Kapellen T., Kaufman E., Klinge A., Klupa T., Krishnaswamy R., Lafferty T., LeGault L., Lambert P., Malecki M. T., Malievsky O., Mathew R., Mathews F., McVie R., Menzel U., Metz C., Meulen J. V. D., Modgil G., Mul D., Muther S., Nuboer R., O'Connell S. M., O'Riordan S., Palko M., Patel K. A., Pesavento R., Piccinno E., Pillai J. K., Pruhova S., Punthakee Z., Rabbone I., Raile K., Rincon M., Rose D., Sanchez J., Sandereson S., Saxena V., Schebek M., Schmidt D., Shehadeh N., Shiels J. P. H., Silva J. M. C. L., Stanik J., Tinklin T., Tjora E., Tumini S., Tuomi T., Uehara A., Velde R. V. D., Vermeulen G., Visser U., Voorhoeve P., Walker J., Weill J., Weisner T., Werner A., Williams T., Woodhead H., oddegard R., Bowman, Pamela, Sulen, Åsta, Barbetti, Fabrizio, Beltrand, Jacque, Svalastoga, Pernille, Codner, Ethel, Tessmann, Ellen H, Juliusson, Petur B, Skrivarhaug, Torild, Pearson, Ewan R, Flanagan, Sarah E, Babiker, Tarig, Thomas, Nicholas J, Shepherd, Maggie H, Ellard, Sian, Klimes, Iwar, Szopa, Magdalena, Polak, Michel, Iafusco, Dario, Hattersley, Andrew T, Njølstad, Pål R, Aisenberg, Javier, Akkurt, Ilker, Abdul-Latif, Hussein, Al-Abdullah, Anee, Barak, Lubomir, Van Den Bergh, Joop, Bertrand, Anne-Marie, Bizzarri, Carla, Bonfanti, Riccardo, Bruel, Henri, Burrows, Anthony, Cadario, Francesco, Cameron, Fergus J., Carson, Denni, Cartigny, Maryse, Cauvin, Vittoria, Cave, Helene, Chakera, Ali, Chetan, Ravi, Chiari, Giovanni, Couch, Bob, Coutant, Régi, Cummings, Elizabeth, Dankovcikova, Adriana, Davis, Liz, Deiss, Dorothee, Delvecchio, Maurizio, Faleschini, Elena, Fauret, Anne-Laure, Finn, Roisin, Ford, Tamsin, Franco, Elisa De, Gallen, Bastian De, Gasperíková, Daniela, Guntamukkala, Padma, Hakeem, Vaseem, Hasegawa, Shinji, Hathout, Eba H., Heffernan, Emmeline, Hill, David, Ho, Josephine, Hoarau, Marie, Holl, Reinhard, Hoddinott, Rebecca, Houghton, Jane, Howard, Neville, Hughes, Natalie, Hunter, Ian, Høgåsen, Anne Kirsti, Kuulasmaa, Helena, Iocara, Sorin, Iotova, Violeta, Irgens, Henrik, Jaap, Alan, Jones, Kenneth, Kapellen, Thoma, Kaufman, Ellen, Klinge, Andrea, Klupa, Tomasz, Krishnaswamy, Ramaiyer, Lafferty, Tony, Legault, Laurent, Lambert, Paul, Malecki, Maciej T, Malievsky, Olag, Mathew, Revi, Mathews, France, Mcvie, Robert, Menzel, Ulrike, Metz, Chantale, Meulen, John Van Der, Modgil, Gita, Mul, Dick, Muther, Silvia, Nuboer, Roo, O'Connell, Susan M., O'Riordan, Stephen, Palko, Miroslav, Patel, Kashyap Amratlal, Pesavento, Roberta, Piccinno, Elvira, Pillai, Janani Kumaraguru, Pruhova, Stephanka, Punthakee, Zubin, Rabbone, Ivana, Raile, Klemen, Rincon, Marielisa, Rose, Danette, Sanchez, Janine, Sandereson, Susan, Saxena, Vinay, Schebek, Martin, Schmidt, Dorothee, Shehadeh, Naim, Shiels, Julian P. H., Silva, Jose M. C. L, Stanik, Juraj, Tinklin, Tracy, Tjora, Erling, Tumini, Stefano, Tuomi, Tiinamaija, Uehara, Akiko, Velde, Robert Van der, Vermeulen, Guido, Visser, Uma, Voorhoeve, Paul, Walker, Jan, Weill, Jaque, Weisner, Tobia, Werner, Andrea, Williams, Toni, Woodhead, Helen, Øddegård, Rønnaug, Bowman, P., Sulen, A., Barbetti, F., Beltrand, J., Svalastoga, P., Codner, E., Tessmann, E. H., Juliusson, P. B., Skrivarhaug, T., Pearson, E. R., Flanagan, S. E., Babiker, T., Thomas, N. J., Shepherd, M. H., Ellard, S., Klimes, I., Szopa, M., Polak, M., Iafusco, D., Hattersley, A. T., Njolstad, P. R., Aisenberg, J., Akkurt, I., Abdul-Latif, H., Al-Abdullah, A., Barak, L., Van Den Bergh, J., Bertrand, A. -M., Bizzarri, C., Bonfanti, R., Bruel, H., Burrows, A., Cadario, F., Cameron, F. J., Carson, D., Cartigny, M., Cauvin, V., Cave, H., Chakera, A., Chetan, R., Chiari, G., Couch, B., Coutant, R., Cummings, E., Dankovcikova, A., Davis, L., Deiss, D., Delvecchio, M., Faleschini, E., Fauret, A. -L., Finn, R., Ford, T., Franco, E. D., Gallen, B. D., Gasperikova, D., Guntamukkala, P., Hakeem, V., Hasegawa, S., Hathout, E. H., Heffernan, E., Hill, D., Ho, J., Hoarau, M., Holl, R., Hoddinott, R., Houghton, J., Howard, N., Hughes, N., Hunter, I., Hogasen, A. K., Kuulasmaa, H., Ioacara, S., Iotova, V., Irgens, H., Jaap, A., Jones, K., Kapellen, T., Kaufman, E., Klinge, A., Klupa, T., Krishnaswamy, R., Lafferty, T., Legault, L., Lambert, P., Malecki, M. T., Malievsky, O., Mathew, R., Mathews, F., Mcvie, R., Menzel, U., Metz, C., Meulen, J. V. D., Modgil, G., Mul, D., Muther, S., Nuboer, R., O'Connell, S. M., O'Riordan, S., Palko, M., Patel, K. A., Pesavento, R., Piccinno, E., Pillai, J. K., Pruhova, S., Punthakee, Z., Rabbone, I., Raile, K., Rincon, M., Rose, D., Sanchez, J., Sandereson, S., Saxena, V., Schebek, M., Schmidt, D., Shehadeh, N., Shiels, J. P. H., Silva, J. M. C. L., Stanik, J., Tinklin, T., Tjora, E., Tumini, S., Tuomi, T., Uehara, A., Velde, R. V. D., Vermeulen, G., Visser, U., Voorhoeve, P., Walker, J., Weill, J., Weisner, T., Werner, A., Williams, T., Woodhead, H., and Oddegard, R.

Subjects
Endocrinology, Endocrinology, Diabetes and Metabolism, Internal Medicine
Abstract

Background: KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potassium channel activation. 90% of patients successfully transfer from insulin to oral sulfonylureas with excellent initial glycaemic control; however, whether this control is maintained in the long term is unclear. Sulfonylurea failure is seen in about 44% of people with type 2 diabetes after 5 years of treatment. Therefore, we did a 10-year multicentre follow-up study of a large international cohort of patients with KCNJ11 permanent neonatal diabetes to address the key questions relating to long-term efficacy and safety of sulfonylureas in these patients. Methods: In this multicentre, international cohort study, all patients diagnosed with KCNJ11 permanent neonatal diabetes at five laboratories in Exeter (UK), Rome (Italy), Bergen (Norway), Paris (France), and Krakow (Poland), who transferred from insulin to oral sulfonylureas before Nov 30, 2006, were eligible for inclusion. Clinicians collected clinical characteristics and annual data relating to glycaemic control, sulfonylurea dose, severe hypoglycaemia, side-effects, diabetes complications, and growth. The main outcomes of interest were sulfonylurea failure, defined as permanent reintroduction of daily insulin, and metabolic control, specifically HbA 1c and sulfonylurea dose. Neurological features associated with KCNJ11 permanent neonatal diabetes were also assessed. This study is registered with ClinicalTrials.gov, number NCT02624817. Findings: 90 patients were identified as being eligible for inclusion and 81 were enrolled in the study and provided long-term (>5·5 years cut-off) outcome data. Median follow-up duration for the whole cohort was 10·2 years (IQR 9·3–10·8). At most recent follow-up (between Dec 1, 2012, and Oct 4, 2016), 75 (93%) of 81 participants remained on sulfonylurea therapy alone. Excellent glycaemic control was maintained for patients for whom we had paired data on HbA 1c and sulfonylurea at all time points (ie, pre-transfer [for HbA 1c ], year 1, and most recent follow-up; n=64)—median HbA 1c was 8·1% (IQR 7·2–9·2; 65·0 mmol/mol [55·2–77·1]) before transfer to sulfonylureas, 5·9% (5·4–6·5; 41·0 mmol/mol [35·5–47·5]; p

Published
2018

155. The ITER toroidal field model coil project

Author

Ulbricht, A., Duchateau, J.L., Fietz, W.H., Ciazynski, D., Fillunger, H., Fink, S., Heller, R., Maix, R., Nicollet, S., Raff, S., Ricci, M., Salpietro, E., Zahn, G., Zanino, R., Bagnasco, M., Besette, D., Bobrov, E., Bonicelli, T., Bruzzone, P., Darweschsad, M.S., Decool, P., Dolgetta, N., della Corte, A., Formisano, A., Grünhagen, A., Hertout, P., Herz, W., Huguet, M., Hurd, F., Ilyin, Yu., Komarek, P., Libeyre, P., Marchese, V., Marinucci, C., Martinez, A., Martone, R., Martovetsky, N., Michael, P., Mitchell, N., Nijhuis, A., Nöther, G., Nunoya, Y., Polak, M., Portone, A., Savoldi Richard, L., Spadoni, M., Süßer, M., Turtú, S., Vostner, A., Takahashi, Y., Wüchner, F., and Zani, L.

Published
2005
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162. Strain and Band-Gap Engineering in Ge-Sn Alloys via P Doping

Author

Prucnal, S., Berencén, Y., Wang, M., Grenzer, J., Voelskow, M., Hübner, R., Yamamoto, Y., Scheit, A., Bärwolf, F., Zviagin, V., Schmidt-Grund, R., Grundmann, M., Żuk, J., Turek, M., Droździel, A., Pyszniak, K., Kudrawiec, R., Polak, M. P., Rebohle, L., Skorupa, W., Helm, M., and Zhou, S.

Subjects
GeSn, Condensed Matter::Materials Science, Condensed Matter - Materials Science, Ge, strain, x-ray diffraction, Raman spectroscopy, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences, ion implantation, n-type doping
Abstract

Ge with a quasi-direct band gap can be realized by strain engineering, alloying with Sn, or ultrahigh n-type doping. In this work, we use all three approaches together to fabricate direct-band-gap Ge-Sn alloys. The heavily doped n-type Ge-Sn is realized with CMOS-compatible nonequilibrium material processing. P is used to form highly doped n-type Ge-Sn layers and to modify the lattice parameter of P-doped Ge-Sn alloys. The strain engineering in heavily-P-doped Ge-Sn films is confirmed by x-ray diffraction and micro Raman spectroscopy. The change of the band gap in P-doped Ge-Sn alloy as a function of P concentration is theoretically predicted by density functional theory and experimentally verified by near-infrared spectroscopic ellipsometry. According to the shift of the absorption edge, it is shown that for an electron concentration greater than 1x10^20 cm-3 the band-gap renormalization is partially compensated by the Burstein-Moss effect. These results indicate that Ge-based materials have high potential for use in near-infrared optoelectronic devices, fully compatible with CMOS technology., 20 pages, 6 figures

Published
2019

164. Band gap renormalization in n-type Ge and GeSn alloys made by millisecond range flash lamp annealing

Author

Prucnal, S., Berencen, Y., Wang, M., Rebohle, L., Kudrawiec, R., Polak, M., Zviagin, V., Schmidt-Grund, R., Grundmann, M., Grenzer, J., Turek, M., Droździel, A., Pyszniak, K., Zuk, J., Helm, M., Skorupa, W., and Zhou, S.

Subjects
GeSn, Ge, FLA, ion implantation, Raman
Abstract

The last missing piece of puzzle for the full functionalization of group IV optoelectronic devices is the direct band gap semiconductor made by CMOS compatible technology. Here we report on the fabrication of GeSn alloys with a Sn concentration of up to 6 % using ion implantation followed by ms-range explosive solid phase epitaxy. The n-type single crystalline GeSn alloys are made by co-doping of Sn and P into Ge. Both the activation of P and the formation of GeSn are performed during a single-step flash lamp annealing for 3 ms. The band gap engineering in ultra-doped n-type Ge and GeSn alloys is theoretically predicted by density functional theory and experimentally verified using ellipsometric spectroscopy. We demonstrate that both the diffusion and the segregation of Sn and P atoms in Ge are fully supressed by ms-range non-equilibrium thermal processing.

Published
2019

165. Terra sigillata van het Thermenterrein in Heerlen

Author

Niemeijer, R.A.J. and Polak, M.

Subjects
Auxiliaria, Europe in a Changing World, The Ancient World
Abstract

Contains fulltext : 209374pub.pdf (Publisher’s version ) (Open Access) 141 p.

Published
2019

169. Direct optical transitions at K- and H-point of Brillouin zone in bulk MoS2, MoSe2, WS2, and WSe2.

Author

Kopaczek, J., Polak, M. P., Scharoch, P., Wu, K., Chen, B., Tongay, S., and Kudrawiec, R.

Subjects
*REFLECTANCE, *BRILLOUIN scattering, *BRILLOUIN zones, *ELECTRONIC band structure, *WAVE mechanics, *ENERGY-band theory of solids
Abstract

Modulated reflectance (contactless electroreflectance (CER), photoreflectance (PR), and piezoreflectance (PzR)) has been applied to study direct optical transitions in bulk MoS2, MoSe2, WS2, and WSe2. In order to interpret optical transitions observed in CER, PR, and PzR spectra, the electronic band structure for the four crystals has been calculated from the first principles within the density functional theory for various points of Brillouin zone including K and H points. It is clearly shown that the electronic band structure at H point of Brillouin zone is very symmetric and similar to the electronic band structure at K point, and therefore, direct optical transitions at H point should be expected in modulated reflectance spectra besides the direct optical transitions at the K point of Brillouin zone. This prediction is confirmed by experimental studies of the electronic band structure of MoS2, MoSe2, WS2, and WSe2 crystals by CER, PR, and PzR spectroscopy, i.e., techniques which are very sensitive to critical points of Brillouin zone. For the four crystals besides the A transition at K point, an AH transition at H point has been observed in CER, PR, and PzR spectra a few tens of meV above the A transition. The spectral difference between A and AH transition has been found to be in a very good agreement with theoretical predictions. The second transition at the H point of Brillouin zone (BH transition) overlaps spectrally with the B transition at K point because of small energy differences in the valence (conduction) band positions at H and K points. Therefore, an extra resonance which could be related to the BH transition is not resolved in modulated reflectance spectra at room temperature for the four crystals. [ABSTRACT FROM AUTHOR]

Published
2016
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170. Direct optical transitions at K- and H-point of Brillouin zone in bulk MoS2, MoSe2, WS2, and WSe2.

Author

Kopaczek, J., Polak, M. P., Scharoch, P., Wu, K., Chen, B., Tongay, S., and Kudrawiec, R.

Subjects
REFLECTANCE, BRILLOUIN scattering, BRILLOUIN zones, ELECTRONIC band structure, WAVE mechanics, ENERGY-band theory of solids
Abstract

Modulated reflectance (contactless electroreflectance (CER), photoreflectance (PR), and piezoreflectance (PzR)) has been applied to study direct optical transitions in bulk MoS2, MoSe2, WS2, and WSe2. In order to interpret optical transitions observed in CER, PR, and PzR spectra, the electronic band structure for the four crystals has been calculated from the first principles within the density functional theory for various points of Brillouin zone including K and H points. It is clearly shown that the electronic band structure at H point of Brillouin zone is very symmetric and similar to the electronic band structure at K point, and therefore, direct optical transitions at H point should be expected in modulated reflectance spectra besides the direct optical transitions at the K point of Brillouin zone. This prediction is confirmed by experimental studies of the electronic band structure of MoS2, MoSe2, WS2, and WSe2 crystals by CER, PR, and PzR spectroscopy, i.e., techniques which are very sensitive to critical points of Brillouin zone. For the four crystals besides the A transition at K point, an AH transition at H point has been observed in CER, PR, and PzR spectra a few tens of meV above the A transition. The spectral difference between A and AH transition has been found to be in a very good agreement with theoretical predictions. The second transition at the H point of Brillouin zone (BH transition) overlaps spectrally with the B transition at K point because of small energy differences in the valence (conduction) band positions at H and K points. Therefore, an extra resonance which could be related to the BH transition is not resolved in modulated reflectance spectra at room temperature for the four crystals. [ABSTRACT FROM AUTHOR]

Published
2016
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172. Contributors to Volume 10

Author

Adams, D.A., primary, Andersen, J.N., additional, Baddeley, C.J., additional, Bardi, U., additional, Barnes, C.J., additional, Bertolini, J.C., additional, Bozzolo, G., additional, Garces, J.E., additional, Hrbek, J., additional, Jugnet, Y., additional, Polak, M., additional, Niehus, H., additional, NØrskov, J.K., additional, Rodriguez, J.A., additional, Ruban, A.V., additional, Rubinovich, L., additional, Schmid, M., additional, Skriver, H.L., additional, Speller, S., additional, Varga, P., additional, Vlieg, E., additional, and Woodruff, D.P., additional

Published
2002
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178. Abstracts of papers and posters Pharmacological Meeting

Author

Adan, Roger A. H., Peter, J., Burbach, H., Gispen, Willem -Hendrik, Bax, Willem A., Saxena, Pramod R., Beenen, O. H. M., Pfaffendorf, M., van Zwieten, P. A., Biewenga, G. Ph., Nicastia, A. J., Haenen, G. R. M. M., Bast, A., Bouwknecht, J. A., Molewijk, H. E., van der Poel, A. M., Mos, J., Olivier, B., Broersen, L. M., Heinsbroek, R. P. W., de Bruin, J. P. C., Brouwers, D. L., Nelissen-Vrancken, H. J. M. G., Smits, J. F. M., Bruning, T. A., Kemme, M. J. B., Chang, P. C., Muizert, Y., Buckley, Theresa L., Nijkamp, Frans P., Cappendijk, S. L. T., Duval, S. Y., De Vries, R., Dzoljic, M. R., Compaan, J. C., Groenink, L., van der Gugten, J., Cox, E. H., van Hemert, A. G. N., de Jong, E., Danhof, M., Crijns, F. R. L., Wolffenbuttel, B. H. R., van Essen, H., Boudier, H. A. J. Struijker, Dam, J. P. M., Doornekamp, F. N. G., Velema, E., Post, M. J., Borst, C., de Boer, J., Meurs, H., Bottone, A. E., Koopal, M., Visser, J. C., Zaagsma, J., de Lannoy, L. M., Danser, A. H. J., Bouhuizen, A. M. B., Schoemaker, R. G., Saxena, P. R., Schalekamp, M. A. D. H., de Vlieger, J. F., van den Wijngaard, P., Koster, A. Sj., Buckley, T. L., Wilting, J., van Heuven-Nolsen, D., Nijkamp, F., Du, X. Y., Bos, E., Dubois, E. A., Vermeulen, R. J., Janssen, A. F. M., van Royen, E. A., Gaillard, P. J., de Boer, A. G., Breimer, D. D., Garrelds, I. M., de Graaf-in't Veld, C., van Wijk, R. Gerth, Zijlstra, F. J., Gerrits, Mirjam A. F. M., Patkina, Nadezda, Zvartau, Edwin E., van Ree, Jan M., Gho, B. C. G., Verdouw, P. D., Gingras, M. A., Cools, A. R., Gommans, J., Hijzen, T., Maes, R. A., Verdouw, P. M., Herremans, A. H. J., Hijzen, T. H., Slangen, J. L., Hoiting, B. H., Schuiling, M., Elzinga, C. R. S., Hoogstraate, A. J., Verhoef, J., Schrijvers, A. H. G. J., Pijpers, A., van Leengoed, L. A. M. G., Verheijden, J. H. M., Junginger, H. E., Boddé, H. E., Hüsken, B. C. P., Joordens, R. J. E., Kalkman, E. A. J., Bilgin, M. Y., Kam, K. L., Kraneveld, A. D., Muis, T., Nijkamp, F. P., Madretsma, G. S., van Dijk, A. P. M., Wilson, J. H. P., Mohede, C. M., Van Oosterhout, J. M., Niikamp, F. P., Nestby, P., Visser, D., Wardeh, G., Hogenboom, F., Mulder, A. H., Schoffelmeer, A. N. M., Oosting, J., Struijker Boudier, H. A. J., Janssen, B. J. A., Passier, P. C. J. J., Verluyten, M. J. A., Drexler, H., Daemen, M. J. A. P., Hashjin, Gudarz Sadeghi, Henricks, Paul A. J., Folkerts, Gert, Shirmohammadi, Mahnaz, Niikamp, Frans P., Santing, R. E., Olymulder, C. G., van der Molen, K., Scheerens, Heleen, Van Loveren, Henk, Sipma, H., den Hertog, A., Nelemans, A., Smit, J., Coppes, R. P., Tintelen, E. J. J. v., Roffel, A. F., Smit, M. J., Leurs, Rob, Timmerman, H., Stam, W. B., Avezaat, C. J. J., Stolte, J., Schiffers, P. M. H., Boudier, H. A. J. Struyker, ten Berge, R. E. J., Krikke, M., Teisman, B. C. H., Tjon, G. H. K., Michiels, N., Voorn, P., van Bergen, P., De Wildt, D. J., Versteeg, D. H. G., van den Tweel, M. C., Bloemen, P. G. M., Henricks, P. A. J., Engels, F., Blomjous, F. J., van der Geest, R., van Laar, T., Roos, R. A. C., van de Velde, M. J., van Kats, J. P., Sassen, L. M. A., Polak, M. P. J., Derkx, F. H. M., van Kesteren, C. A. M., Lamers, J. M. J., van Heugten, H. A. A., van Meeteren, N. L. U., Frankhuyzen-Sierevogel, A., Brakkee, J. H., Wiegant, V. M., Gispen, W. H., Vroom, M. B., van Wezel, H. B., Timmenga, E. J. F., van der Horst, C. M. A. M., Winkler Prins, E. A., Zwavelina, J., Maas, A., Zhang, J., Zwaveling, J., Jansen, F. P., Mochizuki, T., Yamatodani, A., Masereeuw, R., Moons, W. M., Russel, F. G. M., van de Meent, H., van den Berg, C., Wemer, J., Vleeming, W., Kasbergen, C. M., van der Aa, E. M., Wouterse, A. C., Peereboom-Stegeman, J. H. J. Copius, Hessel, E. M., Van Oosterhout, A. J. M., de Bie, J. J., Hofman, G., and Van Loveren, H.

Published
1994
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179. The effect of the maximum processing temperature on the microstructure and electrical properties of melt processed Ag-sheathed Bi2Sr2CaCu2Ox tape

Author

Polak, M., Zhang, W., Polyanskii, A., Pashitski, A., Hellstrom, E.E., and Larbalestier, D.C.

Subjects
Microstructure -- Research, Magnetic tapes -- Research, Density currents -- Research, Business, Electronics, Electronics and electrical industries
Abstract

A study was conducted on the influence of the maximum processing temperature (MPT) on the electrical properties and microstructure of melt processed Ag-sheathed Bi2Sr2CaCu2Ox tapes. Results reveal that the optimum MPT was 894-896-degrees celsius and that this decreases through variations of +/-2-degrees celsius. For tapes that were processed at the optimum MPT, the density and Vickers hardness of the oxide core were found to be at a maximum.

Published
1997

180. Study of the effect of the Sr/Ca ratio on the microstructure and critical current density of BSCCO 2212 Ag-sheathed tapes

Author

zhang, W., Pupysheva, O.V., Ma, Y., Polak, M., Hellstrom, E.E., and Larbalestier, D.C.

Subjects
Magnetic tapes -- Research, Microstructure -- Research, Density currents -- Research, Business, Electronics, Electronics and electrical industries
Abstract

An analysis was conducted on the influence of the Sr/Ca ratio on the critical current density and microstructure of BSCCO 2212 silver-sheathed tapes. Modifications in the Sr/Ca ration was found to change the 2212 phase melting temperature, the phase assemblages in the melt and the fully processed tape's nonsuperconducting phases. The most homogeneous microstructure and highest critical current density were observed in tapes with overall composition 2.1:2:1:2.

Published
1997

184. Electromagnetic properties of Bi-2223/Ag concentric tapes

Author

Majoros, M., Polak, M., Kvitkovic, J., Suchon, D., Martini, L., Ottoboni, V., and Zannella, S.

Subjects
High temperature superconductors -- Evaluation, Electric conductors -- Evaluation, Electrical cables -- Evaluation, Business, Electronics, Electronics and electrical industries
Abstract

It is well established that near the silver interface highly textured Bi-2223 layers compared to the inner ceramic core may be obtained. Thus Bi-2223 multilayered concentric tapes with silver matrix are very promising in increasing transport critical current densities. In the present work we report on the electromagnetic characterization of short tapes having in their cross-section a very thin HTS flattened ring with Ag inside and outside of it. The samples were prepared by the powder in tube method and have self-field critical current densities [J.sub.c] of the order of 3x[10.sup.4] A/[cm.sup.2] at 77 K. Transport and SQUID magnetization measurements revealed weak link nature of the samples in low magnetic fields. Large transport [J.sub.c](B) hysteresis was observed at 4.2 K and magnetic fields up to 20 T. Magnetic field profiles measurements with miniature Hall sensors are in qualitative accordance with model calculations supposing homogeneous current density distribution across the superconducting core.

Published
1996

186. Effectiveness and safety of the tri-iodothyronine analogue Triac in children and adults with MCT8 deficiency: an international, single-arm, open-label, phase 2 trial

Author

Groeneweg, S., Peeters, R.P., Moran, C., Stoupa, A., Auriol, F., Tonduti, D., Dica, A., Paone, L., Rozenkova, K., Malikova, J., Walt, A. van der, Coo, I.F.M. de, McGowan, A., Lyons, G., Aarsen, F.K., Barca, D., Beynum, I.M. van, Knoop, M.M. van der, Jansen, J, Manshande, M., Lunsing, R.J., Nowak, S., Uil, C.A. den, Zillikens, M.C., Visser, F.E., Vrijmoeth, P., Wit, M.C. de, Wolf, N.I., Zandstra, A., Ambegaonkar, G., Singh, Y., Rijke, Y.B. de, Medici, M., Bertini, E.S., Depoorter, S., Lebl, J., Cappa, M., Meirleir, L. de, Krude, H., Craiu, D., Zibordi, F., Petit, I., Polak, M, Chatterjee, K., Visser, T.J., Visser, W.E., Groeneweg, S., Peeters, R.P., Moran, C., Stoupa, A., Auriol, F., Tonduti, D., Dica, A., Paone, L., Rozenkova, K., Malikova, J., Walt, A. van der, Coo, I.F.M. de, McGowan, A., Lyons, G., Aarsen, F.K., Barca, D., Beynum, I.M. van, Knoop, M.M. van der, Jansen, J, Manshande, M., Lunsing, R.J., Nowak, S., Uil, C.A. den, Zillikens, M.C., Visser, F.E., Vrijmoeth, P., Wit, M.C. de, Wolf, N.I., Zandstra, A., Ambegaonkar, G., Singh, Y., Rijke, Y.B. de, Medici, M., Bertini, E.S., Depoorter, S., Lebl, J., Cappa, M., Meirleir, L. de, Krude, H., Craiu, D., Zibordi, F., Petit, I., Polak, M, Chatterjee, K., Visser, T.J., and Visser, W.E.

Abstract

Contains fulltext : 215609.pdf (publisher's version ) (Closed access), BACKGROUND: Deficiency of the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) causes severe intellectual and motor disability and high serum tri-iodothyronine (T3) concentrations (Allan-Herndon-Dudley syndrome). This chronic thyrotoxicosis leads to progressive deterioration in bodyweight, tachycardia, and muscle wasting, predisposing affected individuals to substantial morbidity and mortality. Treatment that safely alleviates peripheral thyrotoxicosis and reverses cerebral hypothyroidism is not yet available. We aimed to investigate the effects of treatment with the T3 analogue Triac (3,3',5-tri-iodothyroacetic acid, or tiratricol), in patients with MCT8 deficiency. METHODS: In this investigator-initiated, multicentre, open-label, single-arm, phase 2, pragmatic trial, we investigated the effectiveness and safety of oral Triac in male paediatric and adult patients with MCT8 deficiency in eight countries in Europe and one site in South Africa. Triac was administered in a predefined escalating dose schedule-after the initial dose of once-daily 350 mug Triac, the daily dose was increased progressively in 350 mug increments, with the goal of attaining serum total T3 concentrations within the target range of 1.4-2.5 nmol/L. We assessed changes in several clinical and biochemical signs of hyperthyroidism between baseline and 12 months of treatment. The prespecified primary endpoint was the change in serum T3 concentrations from baseline to month 12. The co-primary endpoints were changes in concentrations of serum thyroid-stimulating hormone (TSH), free and total thyroxine (T4), and total reverse T3 from baseline to month 12. These analyses were done in patients who received at least one dose of Triac and had at least one post-baseline evaluation of serum throid function. This trial is registered with ClinicalTrials.gov, number NCT02060474. FINDINGS: Between Oct 15, 2014, and June 1, 2017, we screened 50 patients, all of whom were eligible. Of these patient

Published
2019

187. Band gap renormalization in n-type Ge and GeSn alloys made by millisecond range flash lamp annealing

Author

(0000-0002-4088-6032) Prucnal, S., (0000-0003-3529-0207) Berencen, Y., (0000-0003-4606-7203) Wang, M., (0000-0002-8066-6392) Rebohle, L., Kudrawiec, R., Polak, M., Zviagin, V., Schmidt-Grund, R., Grundmann, M., Grenzer, J., Turek, M., Droździel, A., Pyszniak, K., Zuk, J., Helm, M., Skorupa, W., (0000-0002-4885-799X) Zhou, S., (0000-0002-4088-6032) Prucnal, S., (0000-0003-3529-0207) Berencen, Y., (0000-0003-4606-7203) Wang, M., (0000-0002-8066-6392) Rebohle, L., Kudrawiec, R., Polak, M., Zviagin, V., Schmidt-Grund, R., Grundmann, M., Grenzer, J., Turek, M., Droździel, A., Pyszniak, K., Zuk, J., Helm, M., Skorupa, W., and (0000-0002-4885-799X) Zhou, S.

Abstract

The last missing piece of puzzle for the full functionalization of group IV optoelectronic devices is the direct band gap semiconductor made by CMOS compatible technology. Here we report on the fabrication of GeSn alloys with a Sn concentration of up to 6 % using ion implantation followed by ms-range explosive solid phase epitaxy. The n-type single crystalline GeSn alloys are made by co-doping of Sn and P into Ge. Both the activation of P and the formation of GeSn are performed during a single-step flash lamp annealing for 3 ms. The band gap engineering in ultra-doped n-type Ge and GeSn alloys is theoretically predicted by density functional theory and experimentally verified using ellipsometric spectroscopy. We demonstrate that both the diffusion and the segregation of Sn and P atoms in Ge are fully supressed by ms-range non-equilibrium thermal processing.

Published
2019

191. Superconducting dc/ac magnetic system for loss and magnetization experiments operating up to 50/60 Hz

Author

Polak, M., Pitel, J., Majoros, M., Kokavec, J., Suchon, D., Kedrova, M., Kvitkovic, J., Fikis, H., and Kirchmayr, H.

Subjects
Electric measurements -- Equipment and supplies, Superconducting magnets -- Design and construction, Measuring instruments -- Design and construction, Business, Electronics, Electronics and electrical industries
Abstract

The use of two coaxial ac coils is proposed as a means of solving the problem of ac-dc coil coupling in apparatus used to carry out loss and magnetization measurements. The approach has been implemented in a dc-ac superconducting magnet system for operation at 50 Hz and 60 Hz. The instrument generates an ac field ranging from 0.4 T to 1.1 T which is superimposed on a dc magnetic field of up to four tesla.

Published
1995

194. Electric field and losses at AC self field mode in MF composites

Author

Fukui, S., Hlasnik, I., Tsukamoto, O., Amemiya, N., Polak, M., and Kottman, P.

Subjects
Electric fields -- Research, Magnetic fields -- Research, Alternating current -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Studies of the current-voltage characteristics of typical superconducting wires under static and dynamic conditions up to 50 Hz frequency have revealed much higher instantaneous local loss power densities in an external DC magnetic field than those which occur by magnetization in a transverse AC magnetic field. In this paper, the measured loss characteristics are compared with theoretical ones derived from the critical state model, and the self field AC losses are also estimated. Possible errors that can result by applying the critical state model are discussed.

Published
1994

195. Peculiarities in electromagnetic behavior of MF NbTi composites for AC use

Author

Hlasnik, I., Fukui, S., Amemiya, N., Tsukamoto, O., Ikeda, N., Suzuki, E., Kumano, T., Polak, M., Kokavec, J., Krempasky, L., and Kottman, P.

Subjects
Electromagnetism -- Research, Alternating current -- Research, Niobium alloys -- Research, Titanium alloys -- Research, Business, Electronics, Electronics and electrical industries
Abstract

The paper presents results obtained in the study of the current-voltage characteristics, critical and quenching currents as well as of the AC transport current and magnetization losses in four series of fine filament NbTi composites prepared by Showa Electric Wire & Cable Co., Japan. Complementary measurements have been made also on a commercially available type T AC superconducting wire produced by GEC Alsthom Company, France. The samples differ in filament diameter, matrix thickness between filaments and in the number and structure of filament bundles in the composite. In two series of samples barrier type artificial pinning centers have been introduced to increase [J.sub.c] and decrease the normalized magnetization losses. The conclusions concerning the optimization of multifilamentary composites and cables for AC use at low working magnetic field are briefly reviewed.

Published
1994

197. Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy

Author

Van Maldergem, L, Magré, J, Khallouf, T E, Gedde-Dahl, T, Jr, Delépine, M, Trygstad, O, Seemanova, E, Stephenson, T, Albott, C S, Bonnici, F, Panz, V R, Medina, J-L, Bogalho, P, Huet, F, Savasta, S, Verloes, A, Robert, J-J, Loret, H, de Kerdanet, M, Tubiana-Rufi, N, Mégarbané, A, Maassen, J, Polak, M, Lacombe, D, Kahn, C R, Silveira, E L, D’Abronzo, F H, Grigorescu, F, Lathrop, M, Capeau, J, and O’Rahilly, S

Published
2002

198. Magnetic flux distribution in polycrystalline Bi, Pb-Sr-Ca-Cu-O superconductors in a cyclic state

Author

Paasi, J., Polak, M., Lahtinen, M., Eriksson, J.-T., and Plechacek, V.

Subjects
High temperature superconductors -- Research, Magnetic flux -- Research, Polycrystalline semiconductors -- Research, Business, Electronics, Electronics and electrical industries
Abstract

The utilization of various stages of an external external magnetic field cycle in the characterization of the magnetic flux distribution of polycrystalline Bi, Pb-Sr-Ca-Cu-O superconductors at 77 degrees kelvin is discussed. This involves the utilization of a movable miniature Hall sensor with a small air gap located between two identical cylindrical superconductors. Results show that the presence of inter- and intragranular currents in the polycrystalline superconductors causes incorrect critical current density estimations during standard magnetization measurements.

Published
1993

199. Influence of structure of fine filament NbTi composite on ITS electromagnetic characteristics

Author

Hlasnik, I., Tsukamoto, O., Fukui, S., Kumano, T., Polak, M., Kokavec, J., Majoros, M., Suzuki, E., and Krempasky

Subjects
Superconductors -- Research, Electromagnetic measurements -- Research, Niobium alloys -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Changes in the electromagnetic characteristics of fine filament NbTi composites due to filament diameter, filament spacing and losses in critical current density were investigated. Derived theoretical results were experimentally verified by a sample series involving modern ultrafine NbTi multifilamentary compositescombined with sheet-type artificial pinning centers. Smaller experimental values were obtained compared to its theoretical counterparts.

Published
1993

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